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Shinya Sakai

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Orthomyxoviridae Infections

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Takako Nakagawa; Hiroshi Oka; Shinya Sakai; Makoto Fujimoto; Hirozo Goto; Michiko Jo; Yutaka Shimada; Izumi Tashiro; Naotoshi Shibahara
Keishibukuryogan reduces renal injury in the early stage of renal failure in the remnant kidney model.
Nobuko Imanishi; Tsugunobu Andoh; Naoki Mantani; Shinya Sakai; Katsutoshi Terasawa; Yutaka Shimada; Miyuki Sato; Yuko Katada; Kyouka Ueda; Hiroshi Ochiai
Macrophage-mediated inhibitory effect of Zingiber officinale Rosc, a traditional oriental herbal medicine, on the growth of influenza A/Aichi/2/68 virus.
Nobuko Imanishi; Tsugunobu Andoh; Shinya Sakai; Miyuki Satoh; Yuko Katada; Kyouka Ueda; Katsutoshi Terasawa; Hiroshi Ochiai
Induction of inducible nitric oxide (NO) synthase mRNA and NO production in macrophages infected with influenza A/PR/8 virus and stimulated with its ether-split product.

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2011: Takako Nakagawa; Hiroshi Oka; Shinya Sakai; Makoto Fujimoto; Hirozo Goto; Michiko Jo; Yutaka Shimada; Izumi Tashiro; Naotoshi Shibahara
Keishibukuryogan reduces renal injury in the early stage of renal failure in the remnant kidney model.
Evidence-based complementary and alternative medicine : eCAM 2011;2011():914249.
2006: Nobuko Imanishi; Tsugunobu Andoh; Naoki Mantani; Shinya Sakai; Katsutoshi Terasawa; Yutaka Shimada; Miyuki Sato; Yuko Katada; Kyouka Ueda; Hiroshi Ochiai
Macrophage-mediated inhibitory effect of Zingiber officinale Rosc, a traditional oriental herbal medicine, on the growth of influenza A/Aichi/2/68 virus.
The American journal of Chinese medicine 2006;34(1):157-69.
2005: Nobuko Imanishi; Tsugunobu Andoh; Shinya Sakai; Miyuki Satoh; Yuko Katada; Kyouka Ueda; Katsutoshi Terasawa; Hiroshi Ochiai
Induction of inducible nitric oxide (NO) synthase mRNA and NO production in macrophages infected with influenza A/PR/8 virus and stimulated with its ether-split product.
Microbiology and immunology 2005;49(1):41-8.
2004: Nobuyasu Sekiya; Yutaka Shimada; Atsushi Niizawa; Toshiaki Kogure; Naoki Mantani; Shinya Sakai; Hiroaki Hikiami; Katsutoshi Terasawa
Suppressive effects of Stephania tetrandra on the neutrophil function in patients with rheumatoid arthritis.
Phytotherapy research : PTR 2004;18(3):247-9.
2004: Nobuko Imanishi; Naoki Mantani; Shinya Sakai; Miyuki Sato; Yuko Katada; Kyouka Ueda; Katsutoshi Terasawa; Hiroshi Ochiai
Inducible activity of ginger rhizome (Zingiber offifinale Rosc.) on the mRNA expression of macrophage-inducible nitric oxide (NO) synthase and NO production in a macrophage cell line, RAW264.7 cells.
The American journal of Chinese medicine 2004;32(5):727-35.
2004: Mosaburo Kainuma; Shinya Sakai; Nobuyasu Sekiya; Naoki Mantani; N Ogata; Yutaka Shimada; Katsutoshi Terasawa
The effects of a herbal medicine (Mao-to) in patients with chronic hepatitis C after injection of IFN-beta.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2004;11(1):5-10.
2003: Naoki Mantani; Toshiaki Kogure; Shinya Sakai; Yutaka Shimada; Katutoshi Tarasawa
Reexamination of the relation between menstrual cycle and kampo diagnosis, yin-yang.
The American journal of Chinese medicine 2003;31(1):137-40.
2002: Shinya Sakai; Naoki Mantani; Toshiaki Kogure; Hiroshi Ochiai; Yutaka Shimada; Katsutoshi Terasawa
Gene expression of cell surface antigens in the early phase of murine influenza pneumonia determined by a cDNA expression array technique.
Mediators of inflammation 2002;11(6):359-61.
2002: Naoki Mantani; Toshiaki Kogure; Shinya Sakai; Mosaburo Kainuma; Yuji Kasahara; Atsushi Niizawa; Yutaka Shimada; Katsutoshi Terasawa
A comparative study between excess-dose users and regular-dose users of rhubarb contained in Kampo medicines.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2002;9(5):373-6.
2002: Naoki Mantani; Nobuyasu Sekiya; Shinya Sakai; Toshiaki Kogure; Yutaka Shimada; Katsutoshi Terasawa
Rhubarb use in patients treated with Kampo medicines--a risk for gastric cancer?
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2002;122(6):403-5.
2002: Naoki Mantani; Shinya Sakai; Toshiaki Kogure; Hirozo Goto; Naotoshi Shibahara; Toshiaki Kita; Yutaka Shimada; Katsutoshi Terasawa
Herbal medicine and false-positive results on lymphocyte transformation test.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2002;122(6):399-402.
2002: Naoki Mantani; Toshiaki Kogure; Shinya Sakai; Hirozo Goto; Naotoshi Shibahara; Toshiaki Kita; Yutaka Shimada; Katsutoshi Terasawa
Incidence and clinical features of liver injury related to Kampo (Japanese herbal) medicine in 2,496 cases between 1979 and 1999: problems of the lymphocyte transformation test as a diagnostic method.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2002;9(4):280-7.
2002: Mosaburo Kainuma; Jun Hayashi; Shinya Sakai; Kazuaki Imai; Naoki Mantani; Kazufumi Kohta; Tadamichi Mitsuma; Yutaka Shimada; Seizaburo Kashiwagi; Katsutoshi Terasawa
The efficacy of herbal medicine (kampo) in reducing the adverse effects of IFN-beta in chronic hepatitis C.
The American journal of Chinese medicine 2002;30(2-3):355-67.
2001: Shinya Sakai; Hiroshi Ochiai; Naoki Mantani; Toshiaki Kogure; Naotoshi Shibahara; Katsutoshi Terasawa
Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice.
Mediators of inflammation 2001;10(2):93-6.
2001: Chiharu Kishimoto; H Kawamata; Shinya Sakai; H Shinohara; Hiroshi Ochiai
Enhanced production of macrophage inflammatory protein 2 (MIP-2) by in vitro and in vivo infections with encephalomyocarditis virus and modulation of myocarditis with an antibody against MIP-2.
Journal of virology 2001;75(3):1294-300.
2000: Chiharu Kishimoto; H Kawamata; Shinya Sakai; H Shinohara; Hiroshi Ochiai
Role of MIP-2 in coxsackievirus B3 myocarditis.
Journal of molecular and cellular cardiology 2000;32(4):631-8.
2000: Shinya Sakai; H Kawamata; Naoki Mantani; Toshiaki Kogure; Yutaka Shimada; Katsutoshi Terasawa; T Sakai; Nobuko Imanishi; Hiroshi Ochiai
Therapeutic effect of anti-macrophage inflammatory protein 2 antibody on influenza virus-induced pneumonia in mice.
Journal of virology 2000;74(5):2472-6.
1999: Shinya Sakai; H Kawamata; Toshiaki Kogure; Naoki Mantani; Katsutoshi Terasawa; M Umatake; Hiroshi Ochiai
Inhibitory effect of ferulic acid and isoferulic acid on the production of macrophage inflammatory protein-2 in response to respiratory syncytial virus infection in RAW264.7 cells.
Mediators of inflammation 1999;8(3):173-5.
1997: Shinya Sakai; Hiroshi Ochiai; H Kawamata; Toshiaki Kogure; Yutaka Shimada; K Nakajima; Katsutoshi Terasawa
Contribution of tumor necrosis factor alpha and interleukin-1 alpha on the production of macrophage inflammatory protein-2 in response to respiratory syncytial virus infection in a murine macrophage cell line, RAW264.7.
Journal of medical virology 1997;53(2):145-9.
1997: Shinya Sakai; Hiroshi Ochiai; K Nakajima; Katsutoshi Terasawa
Inhibitory effect of ferulic acid on macrophage inflammatory protein-2 production in a murine macrophage cell line, RAW264.7.
Cytokine 1997;9(4):242-8.
1996: Hiroshi Ochiai; Shinya Sakai; Toshiaki Kogure; T Hirabaytashi; K Nakajima; Katsutoshi Terasawa
Development and some applications of enzyme-linked immunosorbent assay system for murine macrophage inflammatory protein-2 (MIP-2).
Mediators of inflammation 1996;5(3):206-9.
1995: T Hirabayashi; Hiroshi Ochiai; Shinya Sakai; K Nakajima; Katsutoshi Terasawa
Inhibitory effect of ferulic acid and isoferulic acid on murine interleukin-8 production in response to influenza virus infections in vitro and in vivo.
Planta medica 1995;61(3):221-6.