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Naomi Sakashita

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Takenobu Nakagawa; Koji Ohnishi; Naomi Sakashita; Yoshihiro Komohara; Motohiro Takeya
Imprint cytological feature of large cell neuroendocrine carcinoma of the gallbladder: A case report.
Shahzada Khan; Hisao Ogawa; Tatsuya Okamoto; Kohta Oyama; Naomi Sakashita; Tomohiro Sawa; Motohiro Takeya; Hiroshige Yamabe; Koji Enomoto; Shigemoto Fujii; Takaaki Akaike
Potential association of Helicobacter cinaedi with atrial arrhythmias and atherosclerosis.
Koji Ohnishi; Naomi Sakashita; Kenichi Takemura; Yukio Fujiwara; Yoshihiro Komohara; XiaoFeng Lei; Takenobu Nakagawa; Motohiro Takeya
Suppression of TLR4-mediated inflammatory response by macrophage class A scavenger receptor (CD204).

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All Publications

2013: Takenobu Nakagawa; Koji Ohnishi; Naomi Sakashita; Yoshihiro Komohara; Motohiro Takeya
Imprint cytological feature of large cell neuroendocrine carcinoma of the gallbladder: A case report.
The journal of medical investigation : JMI 2013;60(1-2):149-53.
2012: Shahzada Khan; Hisao Ogawa; Tatsuya Okamoto; Kohta Oyama; Naomi Sakashita; Tomohiro Sawa; Motohiro Takeya; Hiroshige Yamabe; Koji Enomoto; Shigemoto Fujii; Takaaki Akaike
Potential association of Helicobacter cinaedi with atrial arrhythmias and atherosclerosis.
Microbiology and immunology 2012;56(3):145-54.
2011: Koji Ohnishi; Naomi Sakashita; Kenichi Takemura; Yukio Fujiwara; Yoshihiro Komohara; XiaoFeng Lei; Takenobu Nakagawa; Motohiro Takeya
Suppression of TLR4-mediated inflammatory response by macrophage class A scavenger receptor (CD204).
Biochemical and biophysical research communications 2011;411(3):516-22.
2011: Yukio Fujiwara; Akinori Hayashida; Keiichiro Tsurushima; Ryoji Nagai; Makiko Yoshitomi; Norika Daiguji; Naomi Sakashita; Motohiro Takeya; Sachiko Tsukamoto; Tsuyoshi Ikeda
Triterpenoids isolated from Zizyphus jujuba inhibit foam cell formation in macrophages.
Journal of agricultural and food chemistry 2011;59(9):4544-52.
2011: Yukio Fujiwara; Naoko Kiyota; Keiichiro Tsurushima; Makiko Yoshitomi; Katsumi Mera; Naomi Sakashita; Motohiro Takeya; Tsuyoshi Ikeda; Tomohiro Araki; Toshihiro Nohara; Ryoji Nagai
Natural compounds containing a catechol group enhance the formation of Nε-(carboxymethyl)lysine of the Maillard reaction.
Free radical biology & medicine 2011;50(7):883-91.
2010: XiaoFeng Lei; Yukio Fujiwara; Catherine C Y Chang; Ta-Yuan Chang; Motohiro Takeya; Naomi Sakashita
Association of ACAT1-positive vesicles with late endosomes/ lysosomes in cholesterol-rich human macrophages.
Journal of atherosclerosis and thrombosis 2010;17(7):740-50.
2010: Naomi Sakashita; Catherine C Y Chang; Xiaofeng Lei; Yukio Fujiwara; Motohiro Takeya; Ta-Yuan Chang
Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity.
Journal of lipid research 2010;51(6):1263-72.
2010: Kenichi Takemura; Naomi Sakashita; Yukio Fujiwara; Yoshihiro Komohara; Xiaofeng Lei; Koji Ohnishi; Hiroshi Suzuki; Tatsuhiko Kodama; Hiroshi Mizuta; Motohiro Takeya
Class A scavenger receptor promotes osteoclast differentiation via the enhanced expression of receptor activator of NF-kappaB (RANK).
Biochemical and biophysical research communications 2010;391(4):1675-80.
2010: Koji Ohnishi; Yoshihiro Komohara; Naomi Sakashita; Ken-Ichi Iyama; Toshihiko Murayama; Motohiro Takeya
Macrophages in Langerhans cell histiocytosis are differentiated toward M2 phenotype: their possible involvement in pathological processes.
Pathology international 2010;60(1):27-34.
2009: Yoshihiro Komohara; Kenichi Takemura; Xiao Feng Lei; Naomi Sakashita; Mamoru Harada; Hiroshi Suzuki; Tatsuhiko Kodama; Motohiro Takeya
Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to upregulation of nitric oxide and interferon-gamma production by tumor-associated macrophages.
Cancer science 2009;100(11):2160-6.
2008: Seiya Inoue; Mika Ohta; Zhenghua Li; Gang Zhao; Yutaka Takaoka; Naomi Sakashita; Kazuhisa Miyakawa; Koji Takada; Hajime Tei; Misao Suzuki; Michio Masuoka; Yoshiyuki Sakaki; Kiyoshi Takahashi; Ken-Ichi Yamamura
Specific pathogen free conditions prevent transthyretin amyloidosis in mouse models.
Transgenic research 2008;17(5):817-26.
2008: Nobuaki Shiraki; Kahoko Umeda; Naomi Sakashita; Motohiro Takeya; Kazuhiko Kume; Shoen Kume
Differentiation of mouse and human embryonic stem cells into hepatic lineages.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(7):731-46.
2008: Naomi Sakashita; Motohiro Yamada; Takenobu Nakagawa; Hideki Yamasaki; Motohiro Takeya
A leiomyomatoid angiomatous neuroendocrine tumor of the myometrium: case study with ultrastructural analysis.
Human pathology 2008;39(5):788-92.
2008: Tsuyoshi Honda; Koichi Kaikita; Kenichi Tsujita; Takanori Hayasaki; Masakazu Matsukawa; Shunichiro Fuchigami; Seigo Sugiyama; Naomi Sakashita; Hisao Ogawa; Motohiro Takeya
Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates myocardial ischemia-reperfusion injury in mice with metabolic disorders.
Journal of molecular and cellular cardiology 2008;44(5):915-26.
2008: Ryoji Nagai; Yukio Fujiwara; Katsumi Mera; Kazuya Yamagata; Naomi Sakashita; Motohiro Takeya
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody.
Journal of immunological methods 2008;332(1-2):112-20.
2007: Naomi Sakashita; Chiharu Yokose; Kazuhiko Fujii; Mitsuhiro Matsumoto; Koji Ohnishi; Motohiro Takeya
Pulmonary tumor thrombotic microangiopathy resulting from metastatic signet ring cell carcinoma of the stomach.
Pathology international 2007;57(6):383-7.
2007: Hironori Kobayashi; Naomi Sakashita; Toshiyuki Okuma; Yasuhiro Terasaki; Kenichi Tsujita; Hiroshi Suzuki; Tatsuhiko Kodama; H Nomori; Michio Kawasuji; Motohiro Takeya
Class A scavenger receptor (CD204) attenuates hyperoxia-induced lung injury by reducing oxidative stress.
The Journal of pathology 2007;212(1):38-46.
2007: Kenichi Tsujita; Koichi Kaikita; Takanori Hayasaki; Tsuyoshi Honda; Hironori Kobayashi; Naomi Sakashita; Hiroshi Suzuki; Tatsuhiko Kodama; Hisao Ogawa; Motohiro Takeya
Targeted deletion of class A macrophage scavenger receptor increases the risk of cardiac rupture after experimental myocardial infarction.
Circulation 2007;115(14):1904-11.
2006: Toshiyuki Okuma; Yasuhiro Terasaki; Naomi Sakashita; Koichi Kaikita; Hironori Kobayashi; Takanori Hayasaki; William Kuziel; Hideo Baba; Motohiro Takeya
MCP-1/CCR2 signalling pathway regulates hyperoxia-induced acute lung injury via nitric oxide production.
International journal of experimental pathology 2006;87(6):475-83.
2006: Naomi Sakashita; Yukio Ando; Katsuki Haraoka; Hisayasu Terazaki; Taro Yamashita; Masaaki Nakamura; Motohiro Takeya
Severe congestive heart failure with cardiac liver cirrhosis 10 years after orthotopic liver transplantation for familial amyloidotic polyneuropathy.
Pathology international 2006;56(7):408-12.
2006: Yoshihiro Komohara; Junko Hirahara; Tomohiro Horikawa; Kyoko Kawamura; Emi Kiyota; Naomi Sakashita; Norie Araki; Motohiro Takeya
AM-3K, an anti-macrophage antibody, recognizes CD163, a molecule associated with an anti-inflammatory macrophage phenotype.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(7):763-71.
2006: Catherine Chang; Ruhong Dong; Akira Miyazaki; Naomi Sakashita; Yi Zhang; Jay Liu; Michael Guo; Bo-Liang Li; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis.
Acta biochimica et biophysica Sinica 2006;38(3):151-6.
2004: Mika Yoshimatsu; Yasuhiro Terasaki; Naomi Sakashita; Emi Kiyota; Hiroo Sato; Luc J van der Laan; Motohiro Takeya
Induction of macrophage scavenger receptor MARCO in nonalcoholic steatohepatitis indicates possible involvement of endotoxin in its pathogenic process.
International journal of experimental pathology 2004;85(6):335-43.
2004: Satoru Suzuki; Seigo Sugiyama; Hiroki Usuku; Nobutaka Hirai; Koichi Kaikita; Naomi Sakashita; Tomohiro Sakamoto; Michihiro Yoshimura; Hisao Ogawa
Heart failure with silent coronary artery spasm exhibiting microscopic focal myocardial necrosis and amyloid-deposition.
Internal medicine (Tokyo, Japan) 2004;43(3):199-203.
2004: Patrick C Reid; Naomi Sakashita; Shigeki Sugii; Yoshiko Ohno-Iwashita; Yukiko Shimada; William F Hickey; Ta-Yuan Chang
A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain.
Journal of lipid research 2004;45(3):582-91.
2003: Naomi Sakashita; Akira Miyazaki; Catherine C Y Chang; Ta-Yuan Chang; Emi Kiyota; Maki Satoh; Yoshihiro Komohara; Peter M Morganelli; Seikoh Horiuchi; Motohiro Takeya
Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: in vivo and in vitro studies.
Laboratory investigation; a journal of technical methods and pathology 2003;83(11):1569-81.
2003: Jun Nishio; Hiroshi Iwasaki; Naomi Sakashita; Seiji Haraoka; Teruto Isayama; Masatoshi Naito; Haruhiko Miyayama; Yuuya Yamashita; Masahiro Kikuchi
Undifferentiated (embryonal) sarcoma of the liver in middle-aged adults: smooth muscle differentiation determined by immunohistochemistry and electron microscopy.
Human pathology 2003;34(3):246-52.
2002: Kazumichi Yamada; Masaki Miura; Haruhiko Miyayama; Naomi Sakashita; Masato Kochi; Yukitaka Ushio
Brain metastases from asymptomatic adenocarcinoma of the pancreas: an autopsy case report.
Surgical neurology 2002;58(5):332-6; discussion 336-7.
2001: Naomi Sakashita; Yukio Ando; Katsunori Jinnouchi; M Yoshimatsu; Hisayasu Terazaki; Konen Obayashi; Motohiro Takeya
Familial amyloidotic polyneuropathy (ATTR Val30Met) with widespread cerebral amyloid angiopathy and lethal cerebral hemorrhage.
Pathology international 2001;51(6):476-80.
2001: X Ling; Ryoji Nagai; Naomi Sakashita; Motohiro Takeya; Seikoh Horiuchi; Kiyoshi Takahashi
Immunohistochemical distribution and quantitative biochemical detection of advanced glycation end products in fetal to adult rats and in rats with streptozotocin-induced diabetes.
Laboratory investigation; a journal of technical methods and pathology 2001;81(6):845-61.
2000: K Yamada; M Miura; Haruhiko Miyayama; Naomi Sakashita; Masato Kochi; Yukitaka Ushio
Diffuse brainstem glioma in a patient with Laurence-Moon-(Bardet-)Biedl syndrome.
Pediatric neurosurgery 2000;33(6):323-7.
2000: Catherine C Y Chang; Naomi Sakashita; Kim Ornvold; Oneil Lee; ET Chang; Ruhong Dong; Song Lin; C Y Lee; Stephen C Strom; R Kashyap; J J Fung; R V Farese; Jean-François Patoiseau; André Delhon; Ta-Yuan Chang
Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine.
The Journal of biological chemistry 2000;275(36):28083-92.
2000: Takeshi Yamashita; Yukio Ando; Konen Obayashi; Hisayasu Terazaki; Naomi Sakashita; K Uchida; E Ohama; Masayuki Ando; Makoto Uchino
Oxidative injury is present in Purkinje cells in patients with olivopontocerebellar atrophy.
Journal of the neurological sciences 2000;175(2):107-10.
2000: Naomi Sakashita; Yukio Ando; Konen Obayashi; Hisayasu Terazaki; Takeshi Yamashita; M Takei; M Kinjo; K Takahashi
Familial amyloidotic polyneuropathy (ATTR Ser50Ile): the first autopsy case report.
Virchows Archiv : an international journal of pathology 2000;436(4):345-50.
2000: Takeshi Yamashita; Yukio Ando; O Bernt Suhr; Masaaki Nakamura; Naomi Sakashita; Per-Ingvar Ohlsson; Hisayasu Terazaki; Konen Obayashi; Makoto Uchino; Masayuki Ando
A new diagnostic procedure to detect unknown transthyretin (TTR) mutations in familial amyloidotic polyneuropathy (FAP).
Journal of the neurological sciences 2000;173(2):154-9.
2000: Naomi Sakashita; Akira Miyazaki; Motohiro Takeya; Seikoh Horiuchi; Catherine C Y Chang; Ta-Yuan Chang; Kiyoshi Takahashi
Localization of human acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissues.
The American journal of pathology 2000;156(1):227-36.
1999: Intissar Anan; Magdy El-Salhy; Yukio Ando; S Forsgren; N Nyhlin; Hisayasu Terazaki; Naomi Sakashita; Ole B Suhr
Colonic enteric nervous system in patients with familial amyloidotic neuropathy.
Acta neuropathologica 1999;98(1):48-54.
1999: Intissar Anan; Magdy El-Salhy; Yukio Ando; N Nyhlin; Hisayasu Terazaki; Naomi Sakashita; Ole B Suhr
Colonic endocrine cells in patients with familial amyloidotic polyneuropathy.
Journal of internal medicine 1999;245(5):469-73.
1999: Naomi Sakashita; Motohiro Takeya; T Kishida; T M Stackhouse; B Zbar; K Takahashi
Expression of von Hippel-Lindau protein in normal and pathological human tissues.
The Histochemical journal 1999;31(2):133-44.
1998: X Ling; Naomi Sakashita; Motohiro Takeya; Ryoji Nagai; Seikoh Horiuchi; Kiyoshi Takahashi
Immunohistochemical distribution and subcellular localization of three distinct specific molecular structures of advanced glycation end products in human tissues.
Laboratory investigation; a journal of technical methods and pathology 1998;78(12):1591-606.
1998: Naomi Sakashita; Yukio Ando; S L Marklund; P Nilsson; K Tashima; Takeshi Yamashita; K Takahashi
Familial amyloidotic polyneuropathy type I with extracellular superoxide dismutase mutation: a case report.
Human pathology 1998;29(10):1169-72.
1998: Akira Miyazaki; Naomi Sakashita; Oneil Lee; Kiyoshi Takahashi; Seikoh Horiuchi; Hideki Hakamata; Peter M Morganelli; Catherine C Y Chang; Ta-Yuan Chang
Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(10):1568-74.
1998: Hideki Hakamata; H Sakaguchi; C Zhang; Naomi Sakashita; Hiroshi Suzuki; Akira Miyazaki; Motohiro Takeya; Kiyoshi Takahashi; N Kitamura; Seikoh Horiuchi
The very low- and intermediate-density lipoprotein fraction isolated from apolipoprotein E-knockout mice transforms macrophages to foam cells through an apolipoprotein E-independent pathway.
Biochemistry 1998;37(39):13720-7.
1998: H Matsuda; Hideki Hakamata; T Kawasaki; Naomi Sakashita; Akira Miyazaki; Kiyoshi Takahashi; Motoaki Shichiri; Seikoh Horiuchi
Molecular cloning, functional expression and tissue distribution of rat acyl-coenzyme A:cholesterol acyltransferase.
Biochimica et biophysica acta 1998;1391(2):193-203.
1998: Shunji Yoshimatsu; Yukio Ando; Hisayasu Terazaki; Naomi Sakashita; S Tada; Takeshi Yamashita; Moritaka Suga; Makoto Uchino; Masayuki Ando
Endoscopic and pathological manifestations of the gastrointestinal tract in familial amyloidotic polyneuropathy type I (Met30).
Journal of internal medicine 1998;243(1):65-72.
1997: K Takahashi; Naomi Sakashita; Yukio Ando; Moritaka Suga; Masayuki Ando
Late onset type I familial amyloidotic polyneuropathy: presentation of three autopsy cases in comparison with 19 autopsy cases of the ordinary type.
Pathology international 1997;47(6):353-9.
1997: Takeshi Yamashita; Yukio Ando; Naomi Sakashita; K Hirayama; Y Tanaka; K Tashima; Makoto Uchino; Masayuki Ando
Role of nitric oxide in the cerebellar degeneration during methylmercury intoxication.
Biochimica et biophysica acta 1997;1334(2-3):303-11.
1995: Yukio Ando; Y Tanaka; Takeshi Yamashita; K Tashima; Naomi Sakashita; Masaaki Nakamura; Makoto Uchino; Masayuki Ando
[Familial amyloidotic polyneuropathy (FAP) type I and the therapies].
Rinshō shinkeigaku = Clinical neurology 1995;35(12):1430-2.
1995: Yukio Ando; S Fujii; Naomi Sakashita; Makoto Uchino; Masayuki Ando
Acquired idiopathic generalized anhidrosis: clinical manifestations and histochemical studies.
Journal of the neurological sciences 1995;132(1):80-3.
1995: Yukio Ando; Y Tanaka; M Nakazato; Bo-Göran Ericzon; Takeshi Yamashita; K Tashima; Naomi Sakashita; Moritaka Suga; Makoto Uchino; Masayuki Ando
Change in variant transthyretin levels in patients with familial amyloidotic polyneuropathy type I following liver transplantation.
Biochemical and biophysical research communications 1995;211(2):354-8.
1995: Yukio Ando; Tomomi Gotoh; Y Kawaguchi; Y Tanaka; Naomi Sakashita; Masayuki Ando
Intranasal L-threo-3,4,-dihydroxyphenylserine in treating diarrhea associated with familial amyloidotic polyneuropathy.
Pharmacotherapy 1995;15(3):345-9.
1995: T Arima; Yukio Ando; Eiko Ando; R Okamura; Naomi Sakashita; Y Tanaka; Makoto Uchino; Masayuki Ando
Secondary amyloidosis with severe autonomic dysfunctions.
Journal of the autonomic nervous system 1995;52(1):77-81.
1994: Yukio Ando; Takeshi Yamashita; Y Tanaka; K Tashima; T Yonehara; Tomomi Gotoh; Naomi Sakashita; Makoto Uchino; Masayuki Ando
Role of nitric oxide in the peripheral vessels of patients with familial amyloidotic polyneuropathy (FAP) type I.
Journal of the autonomic nervous system 1994;50(1):79-85.
1994: Yukio Ando; K Tashima; Y Tanaka; M Nakazato; Bo-Göran Ericzon; Frans Duraj; Naomi Sakashita; E Kimura; Eiko Ando; T Yonehara
Treatment of a Japanese patient with familial amyloidotic polyneuropathy with orthotopic liver transplantation.
Internal medicine (Tokyo, Japan) 1994;33(11):730-2.
1994: Naomi Sakashita; Yukio Ando; T Yonehara; Y Tanaka; Keizo Sato; Makoto Uchino; Masayuki Ando
Role of superoxide dismutase and nitric oxide on the interaction between brain and systemic circulation during brain ischemia.
Biochimica et biophysica acta 1994;1227(1-2):67-73.
1993: Yukio Ando; Y Tanaka; H Ueyama; Naomi Sakashita; T Yonehara; K Higuchi; S Araki
Low plasma apolipoprotein AII levels in human and mouse amyloidosis with mutant transthyretin (Met-30) gene.
Annals of neurology 1993;33(1):101-3.