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Linda Birnbaum

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TOP 3
Linda S Birnbaum; John R Bucher; Kristina A Thayer; Mary S Wolfe
Implementing systematic review at the national toxicology program: status and next steps.
Linda S Birnbaum
State of the science of endocrine disruptors.
Thaddeus T Schug; Nigel J Walker; Christopher Weis; David M Balshaw; Stavros Garantziotis; Anne F Johnson; Srikanth S Nadadur; Linda S Birnbaum
ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials.

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All Publications

2013: Linda S Birnbaum; John R Bucher; Kristina A Thayer; Mary S Wolfe
Implementing systematic review at the national toxicology program: status and next steps.
Environmental health perspectives 2013;121(4):A108-9.
2013: Linda S Birnbaum
State of the science of endocrine disruptors.
Environmental health perspectives 2013;121(4):A107.
2013: Thaddeus T Schug; Nigel J Walker; Christopher Weis; David M Balshaw; Stavros Garantziotis; Anne F Johnson; Srikanth S Nadadur; Linda S Birnbaum
ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials.
Environmental health perspectives 2013;121(4):410-4, 414e1-5.
2013: Linda S Birnbaum
15 years out: reinventing ICCVAM.
Environmental health perspectives 2013;121(2):a40.
2013: John MATTHEW Balbus; Robert Barouki; Linda S Birnbaum; Ruth A Etzel; Peter D Gluckman; Philippe Grandjean; Christine Hancock; Mark A Hanson; Jerrold J Heindel; Kate Hoffman; Génon K Jensen; Ann Keeling; Maria Neira; Cristina Rabadán-Diehl; Johanna Ralston; Kwok-Cho Tang
Early-life prevention of non-communicable diseases.
Lancet 2013;381(9860):3-4.
2013: Linda S Birnbaum
Designing safer chemicals.
Environmental health perspectives 2013;121(1):A9.
2012: Linda S Birnbaum; John R Bucher; Gwen Collman; Anne F Johnson; Thaddeus T Schug; Darryl C Zeldin; Jerrold J Heindel
Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A.
Environmental health perspectives 2012;120(12):1640-4.
2012: Ila Cote; David J Dix; Stephen Wilton Edwards; Paul T Anastas; Linda S Birnbaum; Rebecca M Clark; Peter W Preuss
Advancing the next generation of health risk assessment.
Environmental health perspectives 2012;120(11):1499-502.
2012: Linda S Birnbaum
NIEHS's new strategic plan.
Environmental health perspectives 2012;120(8):a298.
2012: Christina H Drew; Liam R O'Fallon; Kristianna G Pettibone; Gwen Collman; Linda S Birnbaum
Measuring partnership activities: partnerships in environmental public health evaluation metrics manual.
Environmental health perspectives 2012;120(7):a261-2.
2012: Linda S Birnbaum
Environmental chemicals: evaluating low-dose effects.
Environmental health perspectives 2012;120(4):A143-4.
2011: David T Szabo; Janet J Diliberto; Janice K Huwe; Linda S Birnbaum
Differences in tissue distribution of HBCD alpha and gamma between adult and developing mice.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(1):256-63.
2011: David Taylor Szabo; Janet J Diliberto; Heldur Hakk; Janice K Huwe; Linda S Birnbaum
Toxicokinetics of the flame retardant hexabromocyclododecane alpha: effect of dose, timing, route, repeated exposure, and metabolism.
Toxicological sciences : an official journal of the Society of Toxicology 2011;121(2):234-44.
2011: John R Bucher; Kristina A Thayer; Linda S Birnbaum
The Office of Health Assessment and Translation: a problem-solving resource for the National Toxicology Program.
Environmental health perspectives 2011;119(5):A196-7.
2010: Linda S Birnbaum; Ake Bergman
Brominated and chlorinated flame retardants: the San Antonio Statement.
Environmental health perspectives 2010;118(12):A514-5.
2010: Linda S Birnbaum; D S Staskal-Wikoff
5th International PCB Workshop--summary and implications.
Environment international 2010;36(8):814-8.
2010: David T Szabo; Janet J Diliberto; Heldur Hakk; Janice K Huwe; Linda S Birnbaum
Toxicokinetics of the flame retardant hexabromocyclododecane gamma: effect of dose, timing, route, repeated exposure, and metabolism.
Toxicological sciences : an official journal of the Society of Toxicology 2010;117(2):282-93.
2010: Linda S Birnbaum; Paul Jung
Evolution in environmental health: incorporating the infectious disease paradigm.
Environmental health perspectives 2010;118(8):a327-8.
2010: Michele La Merrill; Rachel Harper; Linda S Birnbaum; Robert Cardiff; David Threadgill
Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.
Environmental health perspectives 2010;118(5):596-601.
2010: Linda S Birnbaum
Applying research to public health questions: biologically relevant exposures.
Environmental health perspectives 2010;118(4):A152.
2010: Ronald Hines; Dana Sargent; Herman Autrup; Linda S Birnbaum; Robert L Brent; Nancy G Doerrer; Elaine A Cohen Hubal; Daland R Juberg; Christian Laurent; Robert Luebke; Klaus Olejniczak; Christopher J Portier; William Slikker
Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population.
Toxicological sciences : an official journal of the Society of Toxicology 2010;113(1):4-26.
2009: Michele La Merrill; Bittu S Kuruvilla; Daniel Pomp; Linda S Birnbaum; David Threadgill
Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors.
Environmental health perspectives 2009;117(9):1414-9.
2009: Laura L F Scott; Daniele F Staskal; E Spencer Williams; William J Luksemburg; Jon D Urban; Ly M Nguyen; Laurie C Haws; Linda S Birnbaum; Dennis J Paustenbach; Mark A Harris
Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in southern Mississippi catfish and estimation of potential health risks.
Chemosphere 2009;74(7):1002-10.
2008: Daniele F Staskal; Laura L F Scott; Laurie C Haws; William J Luksemburg; Linda S Birnbaum; Jon D Urban; E Spencer Williams; Dennis J Paustenbach; Mark A Harris
Assessment of polybrominated diphenyl ether exposures and health risks associated with consumption of southern Mississippi catfish.
Environmental science & technology 2008;42(17):6755-61.
2008: Yo-Chan Jeong; Nigel J Walker; DE Burgin; Grace Kissling; Mayetri Gupta; Lawrence Kupper; Linda S Birnbaum; James A Swenberg
Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons.
Free radical biology & medicine 2008;45(5):585-91.
2008: Ralph J Smialowicz; Michael J DeVito; Wanda C Williams; Linda S Birnbaum
Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS.
Toxicology and applied pharmacology 2008;227(3):477-84.
2008: VM Richardson; Daniele F Staskal; DG Ross; Janet J Diliberto; Michael J DeVito; Linda S Birnbaum
Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener.
Toxicology and applied pharmacology 2008;226(3):244-50.
2007: Janice A Dye; Marta Venier; Lingyan Zhu; Cynthia R Ward; Ronald A Hites; Linda S Birnbaum
Elevated PBDE levels in pet cats: sentinels for humans?
Environmental science & technology 2007;41(18):6350-6.
2006: Linda S Birnbaum; Elaine A Cohen Hubal
Polybrominated diphenyl ethers: a case study for using biomonitoring data to address risk assessment questions.
Environmental health perspectives 2006;114(11):1770-5.
2006: Daniele F Staskal; Heldur Hakk; Daniel Bauer; Janet J Diliberto; Linda S Birnbaum
Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice.
Toxicological sciences : an official journal of the Society of Toxicology 2006;94(1):28-37.
2006: Martin van den Berg; Linda S Birnbaum; Michael S Denison; Mike De Vito; William H Farland; Mark Feeley; Hans-Peter Fiedler; Helen Hakansson; Annika Hanberg; Laurie Haws; Martin Rose; Stephen Safe; Dieter Schrenk; Chiharu Tohyama; Angelika Tritscher; Jouko Tuomisto; Mats Tysklind; Nigel Walker; Richard E Peterson
The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds.
Toxicological sciences : an official journal of the Society of Toxicology 2006;93(2):223-41.
2006: Claude Emond; Linda S Birnbaum; Michael J DeVito
Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD.
Environmental health perspectives 2006;114(9):1394-400.
2006: Daniele F Staskal; Janet J Diliberto; Linda S Birnbaum
Disposition of BDE 47 in developing mice.
Toxicological sciences : an official journal of the Society of Toxicology 2006;90(2):309-16.
2006: Daniele F Staskal; Janet J Diliberto; Linda S Birnbaum
Impact of repeated exposure on the toxicokinetics of BDE 47 in mice.
Toxicological sciences : an official journal of the Society of Toxicology 2006;89(2):380-5.
2006: Laurie C Haws; Steave H Su; Mark Harris; Michael J DeVito; Nigel J Walker; William H Farland; Brent L Finley; Linda S Birnbaum
Development of a refined database of mammalian relative potency estimates for dioxin-like compounds.
Toxicological sciences : an official journal of the Society of Toxicology 2006;89(1):4-30.
2005: Claude Emond; Joel Michalek; Linda S Birnbaum; Michael J DeVito
Comparison of the use of a physiologically based pharmacokinetic model and a classical pharmacokinetic model for dioxin exposure assessments.
Environmental health perspectives 2005;113(12):1666-8.
2005: Prasada Rao S Kodavanti; Thomas R Ward; Gabriele Ludewig; Larry W Robertson; Linda S Birnbaum
Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(1):181-92.
2005: Daniele F Staskal; Janet J Diliberto; Michael J DeVito; Linda S Birnbaum
Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals.
Toxicological sciences : an official journal of the Society of Toxicology 2005;84(2):225-31.
2005: Daniele F Staskal; Janet J Diliberto; Michael J DeVito; Linda S Birnbaum
Toxicokinetics of BDE 47 in female mice: effect of dose, route of exposure, and time.
Toxicological sciences : an official journal of the Society of Toxicology 2005;83(2):215-23.
2004: Claude Emond; Linda S Birnbaum; Michael J DeVito
Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(1):115-33.
2004: Ralph J Smialowicz; DE Burgin; Wanda C Williams; Janet J Diliberto; R Woodrow Setzer; Linda S Birnbaum
CYP1A2 is not required for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunosuppression.
Toxicology 2004;197(1):15-22.
2004: Linda S Birnbaum; Daniele F Staskal
Brominated flame retardants: cause for concern?
Environmental health perspectives 2004;112(1):9-17.
2003: Linda S Birnbaum; Daniele F Staskal; Janet J Diliberto
Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs).
Environment international 2003;29(6):855-60.
2003: Jonathan T Hamm; C-Y Chen; Linda S Birnbaum
A mixture of dioxins, furans, and non-ortho PCBs based upon consensus toxic equivalency factors produces dioxin-like reproductive effects.
Toxicological sciences : an official journal of the Society of Toxicology 2003;74(1):182-91.
2003: Linda S Birnbaum; Suzanne E Fenton
Cancer and developmental exposure to endocrine disruptors.
Environmental health perspectives 2003;111(4):389-94.
2002: Suzanne E Fenton; Jonathan T Hamm; Linda S Birnbaum; Geri L. Youngblood
Persistent abnormalities in the rat mammary gland following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Toxicological sciences : an official journal of the Society of Toxicology 2002;67(1):63-74.
2002: Chia-Yang Chen; Jonathan T Hamm; J Ronald Hass; Phillip W Albro; Linda S Birnbaum
A mixture of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and non-ortho polychlorinated biphenyls (PCBs) changed the lipid content of pregnant Long Evans rats.
Chemosphere 2002;46(9-10):1501-4.
2002: BP Slezak; Jonathan T Hamm; J Reyna; Christopher H Hurst; Linda S Birnbaum
TCDD-mediated oxidative stress in male rat pups following perinatal exposure.
Journal of biochemical and molecular toxicology 2002;16(2):49-52.
2002: Linda S Birnbaum; Audrey M Cummings
Dioxins and endometriosis: a plausible hypothesis.
Environmental health perspectives 2002;110(1):15-21.
2002: Christopher H Hurst; Barbara D Abbott; Judith E Schmid; Linda S Birnbaum
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts early morphogenetic events that form the lower reproductive tract in female rat fetuses.
Toxicological sciences : an official journal of the Society of Toxicology 2002;65(1):87-98.
2001: DE Burgin; Janet J Diliberto; Ethel C Derr-Yellin; N Kannan; Prasada Rao S Kodavanti; Linda S Birnbaum
Differential effects of two lots of aroclor 1254 on enzyme induction, thyroid hormones, and oxidative stress.
Environmental health perspectives 2001;109(11):1163-8.
2001: Prasada Rao S Kodavanti; N Kannan; N Yamashita; Ethel C Derr-Yellin; Thomas R Ward; DE Burgin; Hugh A Tilson; Linda S Birnbaum
Differential effects of two lots of aroclor 1254: congener-specific analysis and neurochemical end points.
Environmental health perspectives 2001;109(11):1153-61.
2001: C Y Chen; Jonathan T Hamm; J R Hass; Linda S Birnbaum
Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant long evans rats and the transfer to offspring.
Toxicology and applied pharmacology 2001;173(2):65-88.
2001: Janet J Diliberto; Michael J DeVito; DG Ross; Linda S Birnbaum
Subchronic Exposure of [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism.
Toxicological sciences : an official journal of the Society of Toxicology 2001;61(2):241-55.
2000: Christopher H Hurst; Michael J DeVito; Linda S Birnbaum
Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing long-evans rats following subchronic exposure.
Toxicological sciences : an official journal of the Society of Toxicology 2000;57(2):275-83.
2000: Michael J DeVito; M G Ménache; Janet J Diliberto; DG Ross; Linda S Birnbaum
Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls.
Toxicology and applied pharmacology 2000;167(3):157-72.
2000: X Wang; MJ Santostefano; Michael J DeVito; Linda S Birnbaum
Extrapolation of a PBPK model for dioxins across dosage regimen, gender, strain, and species.
Toxicological sciences : an official journal of the Society of Toxicology 2000;56(1):49-60.
2000: Linda S Birnbaum; J Tuomisto
Non-carcinogenic effects of TCDD in animals.
Food additives and contaminants 2000;17(4):275-88.
2000: Jonathan T Hamm; Barney R Sparrow; D Wolf; Linda S Birnbaum
In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters postnatal development of seminal vesicle epithelium.
Toxicological sciences : an official journal of the Society of Toxicology 2000;54(2):424-30.
2000: BP Slezak; Gary E Hatch; Michael J DeVito; Janet J Diliberto; Ralph Slade; Kay Crissman; Ezdihar A Hassoun; Linda S Birnbaum
Oxidative stress in female B6C3F1 mice following acute and subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Toxicological sciences : an official journal of the Society of Toxicology 2000;54(2):390-8.
2000: Christopher H Hurst; Michael J DeVito; R Woodrow Setzer; Linda S Birnbaum
Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentrations with developmental effects.
Toxicological sciences : an official journal of the Society of Toxicology 2000;53(2):411-20.
1999: Audrey M Cummings; J M Hedge; Linda S Birnbaum
Effect of prenatal exposure to TCDD on the promotion of endometriotic lesion growth by TCDD in adult female rats and mice.
Toxicological sciences : an official journal of the Society of Toxicology 1999;52(1):45-9.
1999: MJ Santostefano; VM Richardson; Nigel J Walker; J Blanton; K O Lindros; George W Lucier; S K Alcasey; Linda S Birnbaum
Dose-dependent localization of TCDD in isolated centrilobular and periportal hepatocytes.
Toxicological sciences : an official journal of the Society of Toxicology 1999;52(1):9-19.
1999: BP Slezak; Janet J Diliberto; Linda S Birnbaum
2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated oxidative stress in CYP1A2 knockout (CYP1A2-/-) mice.
Biochemical and biophysical research communications 1999;264(2):376-9.
1999: Linda S Birnbaum; B T Culpepper
Research integrity: a government perspective.
Quality assurance (San Diego, Calif.) 1999;7(4):217-24.
1999: Janet J Diliberto; DE Burgin; Linda S Birnbaum
Effects of CYP1A2 on disposition of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran, and 2,2',4,4',5,5'-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice.
Toxicology and applied pharmacology 1999;159(1):52-64.
1999: Linda S Birnbaum; BP Slezak
Dietary exposure to PCBs and dioxins in children.
Environmental health perspectives 1999;107(1):1.
1998: Jonathan T Hamm; DG Ross; VM Richardson; Janet J Diliberto; Linda S Birnbaum
Methoxyresorufin: an inappropriate substrate for CYP1A2 in the mouse.
Biochemical pharmacology 1998;56(12):1657-60.
1998: Michael J DeVito; DG Ross; A E Dupuy; J Ferrario; D McDaniel; Linda S Birnbaum
Dose-response relationships for disposition and hepatic sequestration of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls following subchronic treatment in mice.
Toxicological sciences : an official journal of the Society of Toxicology 1998;46(2):223-34.
1998: Martin van den Berg; Linda S Birnbaum; Albertus T C Bosveld; B Brunström; P Cook; Mark Feeley; John P Giesy; Annika Hanberg; R Hasegawa; SW Kennedy; T Kubiak; JC Larsen; FX van Leeuwen; A K Liem; C Nolt; Richard E Peterson; Lorenz Poellinger; Stephen Safe; Dieter Schrenk; Donald E Tillitt; Mats Tysklind; M Younes; F Waern; Timothy R Zacharewski
Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife.
Environmental health perspectives 1998;106(12):775-92.
1998: VM Richardson; MJ Santostefano; Linda S Birnbaum
Daily cycle of bHLH-PAS proteins, Ah receptor and Arnt, in multiple tissues of female Sprague-Dawley rats.
Biochemical and biophysical research communications 1998;252(1):225-31.
1998: Christopher H Hurst; Barbara D Abbott; Michael J DeVito; Linda S Birnbaum
2,3,7,8-Tetrachlorodibenzo-p-dioxin in pregnant Long Evans rats: disposition to maternal and embryo/fetal tissues.
Toxicological sciences : an official journal of the Society of Toxicology 1998;45(2):129-36.
1998: MJ Santostefano; X Wang; VM Richardson; DG Ross; Michael J DeVito; Linda S Birnbaum
A pharmacodynamic analysis of TCDD-induced cytochrome P450 gene expression in multiple tissues: dose- and time-dependent effects.
Toxicology and applied pharmacology 1998;151(2):294-310.
1998: J A Jackson; Linda S Birnbaum; Janet J Diliberto
Effects of age, sex, and pharmacologic agents on the biliary elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in F344 rats.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(7):714-9.
1998: Richard Pollenz; MJ Santostefano; Eric L Klett; VM Richardson; Brian Necela; Linda S Birnbaum
Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung.
Toxicological sciences : an official journal of the Society of Toxicology 1998;42(2):117-28.
1998: Ezdihar A Hassoun; S C Wilt; Michael J DeVito; A Van Birgelen; Naser Z Alsharif; Linda S Birnbaum; Sidney J Stohs
Induction of oxidative stress in brain tissues of mice after subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicological sciences : an official journal of the Society of Toxicology 1998;42(1):23-7.
1997: Michael J DeVito; Janet J Diliberto; DG Ross; M G Menache; Linda S Birnbaum
Dose-response relationships for polyhalogenated dioxins and dibenzofurans following subchronic treatment in mice. I. CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin.
Toxicology and applied pharmacology 1997;147(2):267-80.
1997: X Wang; MJ Santostefano; Marina V Evans; VM Richardson; Janet J Diliberto; Linda S Birnbaum
Determination of parameters responsible for pharmacokinetic behavior of TCDD in female Sprague-Dawley rats.
Toxicology and applied pharmacology 1997;147(1):151-68.
1997: Janet J Diliberto; DE Burgin; Linda S Birnbaum
Role of CYP1A2 in hepatic sequestration of dioxin: studies using CYP1A2 knock-out mice.
Biochemical and biophysical research communications 1997;236(2):431-3.
1997: K L Johnson; Audrey M Cummings; Linda S Birnbaum
Promotion of endometriosis in mice by polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls.
Environmental health perspectives 1997;105(7):750-5.
1997: Ralph J Smialowicz; Michael J DeVito; M M Riddle; Wanda C Williams; Linda S Birnbaum
Opposite effects of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antibody response to sheep erythrocytes in mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1997;37(2):141-9.
1997: MJ Santostefano; DG Ross; U Savas; Colin R Jefcoate; Linda S Birnbaum
Differential time-course and dose-response relationships of TCDD-induced CYP1B1, CYP1A1, and CYP1A2 proteins in rats.
Biochemical and biophysical research communications 1997;233(1):20-4.
1996: MJ Santostefano; K L Johnson; N A Whisnant; VM Richardson; Michael J DeVito; Janet J Diliberto; Linda S Birnbaum
Subcellular localization of TCDD differs between the liver, lungs, and kidneys after acute and subchronic exposure: species/dose comparisons and possible mechanism.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;34(2):265-75.
1996: A P van Birgelen; DG Ross; Michael J DeVito; Linda S Birnbaum
Interactive effects between 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,2',4,4',5,5'-hexachlorobiphenyl in female B6C3F1 mice: tissue distribution and tissue-specific enzyme induction.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;34(1):118-31.
1996: A P van Birgelen; Michael J DeVito; J M Akins; DG Ross; Janet J Diliberto; Linda S Birnbaum
Relative potencies of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls derived from hepatic porphyrin accumulation in mice.
Toxicology and applied pharmacology 1996;138(1):98-109.
1996: M J DeVito; L E Beebe; M Menache; Linda S Birnbaum
Relationship between CYP1A enzyme activities and protein levels in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Journal of toxicology and environmental health 1996;47(4):379-94.
1995: M J DeVito; Linda S Birnbaum
Dioxins: model chemicals for assessing receptor-mediated toxicity.
Toxicology 1995;102(1-2):115-23.
1995: R A Pegram; J J Diliberto; T C Moore; P Gao; Linda S Birnbaum
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) distribution and cytochrome P4501A induction in young adult and senescent male mice.
Toxicology letters 1995;76(2):119-26.
1995: Linda S Birnbaum
Workshop on perinatal exposure to dioxin-like compounds. V. Immunologic effects.
Environmental health perspectives 1995;103 Suppl 2():157-60.
1995: J J Diliberto; P I Akubue; Robert W Luebke; Linda S Birnbaum
Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice.
Toxicology and applied pharmacology 1995;130(2):197-208.
1994: Robert W Luebke; Carey B Copeland; J J Diliberto; P I Akubue; D L Andrews; M M Riddle; Wanda C Williams; Linda S Birnbaum
Assessment of host resistance to Trichinella spiralis in mice following preinfection exposure to 2,3,7,8-TCDD.
Toxicology and applied pharmacology 1994;125(1):7-16.
1994: M J DeVito; X Ma; J G Babish; M Menache; Linda S Birnbaum
Dose-response relationships in mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: CYP1A1, CYP1A2, estrogen receptor, and protein tyrosine phosphorylation.
Toxicology and applied pharmacology 1994;124(1):82-90.
1994: L B Kedderis; J A Jackson; Donald G Patterson; J Grainger; Janet J Diliberto; Linda S Birnbaum
Chemical characterization and disposition studies with 1,2,7,8-tetrabromodibenzofuran in the rat.
Journal of toxicology and environmental health 1994;41(1):53-69.
1994: Melvin Andersen; J J Mills; TR Fox; Thomas L Goldsworthy; Rory B Conolly; Linda S Birnbaum
Receptor-mediated toxicity and implications for risk assessment.
Progress in clinical and biological research 1994;387():295-310.
1993: L B Kedderis; Melvin Andersen; Linda S Birnbaum
Effect of dose, time, and pretreatment on the biliary excretion and tissue distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;21(4):405-11.
1993: L B Kedderis; J J Mills; Melvin Andersen; Linda S Birnbaum
A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat: tissue distribution and CYP1A induction.
Toxicology and applied pharmacology 1993;121(1):87-98.
1993: Janet J Diliberto; L B Kedderis; J A Jackson; Linda S Birnbaum
Effects of dose and routes of exposure on the disposition of 2,3,7,8-[3H]tetrabromodibenzo-p-dioxin (TBDD) in the rat.
Toxicology and applied pharmacology 1993;120(2):315-26.
1993: Y B Anderson; J A Jackson; Linda S Birnbaum
Maturational changes in dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Fischer 344 rats.
Toxicology and applied pharmacology 1993;119(2):214-20.
1993: Melvin Andersen; J J Mills; Michael L Gargas; L Kedderis; Linda S Birnbaum; D Neubert; William F Greenlee
Modeling receptor-mediated processes with dioxin: implications for pharmacokinetics and risk assessment.
Risk analysis : an official publication of the Society for Risk Analysis 1993;13(1):25-36.
1992: R E Morrissey; M W Harris; Janet J Diliberto; Linda S Birnbaum
Limited PCB antagonism of TCDD-induced malformations in mice.
Toxicology letters 1992;60(1):19-25.
1991: T F McMahon; Linda S Birnbaum
Age-related changes in disposition and metabolism of benzene in male C57BL/6N mice.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(6):1052-7.
1991: L B Kedderis; Janet J Diliberto; P Linko; J A Goldstein; Linda S Birnbaum
Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: biliary excretion and induction of cytochromes CYP1A1 and CYP1A2.
Toxicology and applied pharmacology 1991;111(1):163-72.
1991: L B Kedderis; Janet J Diliberto; Linda S Birnbaum
Disposition and excretion of intravenous 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in rats.
Toxicology and applied pharmacology 1991;108(3):397-406.
1991: F H Lin; S J Stohs; Linda S Birnbaum; G Clark; George W Lucier; Joyce A Goldstein
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the hepatic estrogen and glucocorticoid receptors in congenic strains of Ah responsive and Ah nonresponsive C57BL/6J mice.
Toxicology and applied pharmacology 1991;108(1):129-39.
1991: T F McMahon; S A Stefanski; Ralph E Wilson; P C Blair; A M Clark; Linda S Birnbaum
Comparative acute nephrotoxicity of salicylic acid, 2,3-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid in young and middle aged Fischer 344 rats.
Toxicology 1991;66(3):297-311.
1991: L Couture-Haws; M W Harris; M M McDonald; A C Lockhart; Linda S Birnbaum
Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery.
Toxicology and applied pharmacology 1991;107(3):413-28.
1991: L Couture-Haws; M W Harris; A C Lockhart; Linda S Birnbaum
Evaluation of the persistence of hydronephrosis induced in mice following in utero and/or lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicology and applied pharmacology 1991;107(3):402-12.
1991: F H Lin; G Clark; Linda S Birnbaum; George W Lucier; Joyce A Goldstein
Influence of the Ah locus on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the hepatic epidermal growth factor receptor.
Molecular pharmacology 1991;39(3):307-13.
1991: Barbara D Abbott; Linda S Birnbaum
TCDD exposure of human embryonic palatal shelves in organ culture alters the differentiation of medial epithelial cells.
Teratology 1991;43(2):119-32.
1991: Y B Banks; Linda S Birnbaum
Absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) after low dose dermal exposure.
Toxicology and applied pharmacology 1991;107(2):302-10.
1991: Linda S Birnbaum; R E Morrissey; M W Harris
Teratogenic effects of 2,3,7,8-tetrabromodibenzo-p-dioxin and three polybrominated dibenzofurans in C57BL/6N mice.
Toxicology and applied pharmacology 1991;107(1):141-52.
1990: S J Stohs; Barbara D Abbott; F H Lin; Linda S Birnbaum
Induction of ethoxyresorufin-O-deethylase and inhibition of glucocorticoid receptor binding in skin and liver of haired and hairless HRS/J mice by topically applied 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicology 1990;65(1-2):123-36.
1990: Barbara D Abbott; Linda S Birnbaum
TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD.
Toxicology and applied pharmacology 1990;106(3):418-32.
1990: L A Couture; Barbara D Abbott; Linda S Birnbaum
A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism.
Teratology 1990;42(6):619-27.
1990: Barbara D Abbott; Linda S Birnbaum
Retinoic acid-induced alterations in the expression of growth factors in embryonic mouse palatal shelves.
Teratology 1990;42(6):597-610.
1990: C D Hébert; Q L Cao; Linda S Birnbaum
Role of transforming growth factor beta in the proliferative effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on human squamous carcinoma cells.
Cancer research 1990;50(22):7190-7.
1990: Janet J Diliberto; P Srinivas; D Overstreet; G Usha; Leo T Burka; Linda S Birnbaum
Metabolism of citral, an alpha,beta-unsaturated aldehyde, in male F344 rats.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):866-75.
1990: T F McMahon; Linda S Birnbaum
Age-related changes in toxicity and biotransformation of potassium cyanide in male C57BL/6N mice.
Toxicology and applied pharmacology 1990;105(2):305-14.
1990: C D Hébert; Q L Cao; Linda S Birnbaum
Inhibition of high-density growth arrest in human squamous carcinoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Carcinogenesis 1990;11(8):1335-42.
1990: MA Medinsky; William E Bechtold; Linda S Birnbaum; J A Bond; D G Burt; Y S Cheng; N A Gillett; D K Gulati; Charles H Hobbs; J A Pickrell
Effect of inhaled azodicarbonamide on F344/N rats and B6C3F1 mice with 2-week and 13-week inhalation exposures.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(2):308-19.
1990: Linda S Birnbaum; M M McDonald; P C Blair; A M Clark; M W Harris
Differential toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57BL/6J mice congenic at the Ah Locus.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(1):186-200.
1990: Y B Banks; D W Brewster; Linda S Birnbaum
Age-related changes in dermal absorption of 2,3,7, 8-tetrachlorodibenzo-p-dioxin and 2,3,4,7,8-pentachlorodibenzofuran.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(1):163-73.
1990: L A Couture; M W Harris; Linda S Birnbaum
Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(1):142-50.
1990: T F McMahon; Janet J Diliberto; Linda S Birnbaum
Effects of age and dose on disposition and metabolism of salicylic acid in male Fischer 344 rats.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(4):494-503.
1990: Barbara D Abbott; Linda S Birnbaum
Rat embryonic palatal shelves respond to TCDD in organ culture.
Toxicology and applied pharmacology 1990;103(3):441-51.
1990: Barbara D Abbott; L G Hill; Linda S Birnbaum
Processes involved in retinoic acid production of small embryonic palatal shelves and limb defects.
Teratology 1990;41(3):299-310.
1990: C D Hébert; M W Harris; Michael R Elwell; Linda S Birnbaum
Relative toxicity and tumor-promoting ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,4,7,8-pentachlorodibenzofuran (PCDF), and 1,2,3,4,7,8-hexachlorodibenzofuran (HCDF) in hairless mice.
Toxicology and applied pharmacology 1990;102(2):362-77.
1990: Barbara D Abbott; Linda S Birnbaum
Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation.
Teratology 1990;41(1):71-84.
1990: Joyce A Goldstein; F H Lin; S J Stohs; M Graham; G Clarke; Linda S Birnbaum; George W Lucier
The effects of TCDD on receptors for epidermal growth factor, glucocorticoid, and estrogen in Ah-responsive and -nonresponsive congenic mice and the effects of TCDD on estradiol metabolism in a liver tumor promotion model in female rats.
Progress in clinical and biological research 1990;331():187-202.
1989: Barbara D Abbott; M W Harris; Linda S Birnbaum
Etiology of retinoic acid-induced cleft palate varies with the embryonic stage.
Teratology 1989;40(6):533-53.
1989: M W Harris; L C Uraih; Linda S Birnbaum
Acute toxicity of perfluorodecanoic acid in C57BL/6 mice differs from 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1989;13(4):723-36.
1989: T F McMahon; Janet J Diliberto; Linda S Birnbaum
Age-related changes in the disposition of benzyl acetate. A model compound for glycine conjugation.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(5):506-12.
1989: Barbara D Abbott; Janet J Diliberto; Linda S Birnbaum
2,3,7,8-Tetrachlorodibenzo-p-dioxin alters embryonic palatal medial epithelial cell differentiation in vitro.
Toxicology and applied pharmacology 1989;100(1):119-31.
1989: D W Brewster; Linda S Birnbaum
The biochemical toxicity of perfluorodecanoic acid in the mouse is different from that of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicology and applied pharmacology 1989;99(3):544-54.
1989: Barbara D Abbott; Linda S Birnbaum
Cellular alterations and enhanced induction of cleft palate after coadministration of retinoic acid and TCDD.
Toxicology and applied pharmacology 1989;99(2):287-301.
1989: Barbara D Abbott; Linda S Birnbaum
TCDD alters medial epithelial cell differentiation during palatogenesis.
Toxicology and applied pharmacology 1989;99(2):276-86.
1989: C D Hébert; Linda S Birnbaum
Lack of correlation between sensitivity to growth inhibition and receptor number for transforming growth factor beta in human squamous carcinoma cell lines.
Cancer research 1989;49(12):3196-202.
1989: Linda S Birnbaum; M W Harris; L M Stocking; A M Clark; R E Morrissey
Retinoic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin selectively enhance teratogenesis in C57BL/6N mice.
Toxicology and applied pharmacology 1989;98(3):487-500.
1989: R P Ryan; G I Sunahara; George W Lucier; Linda S Birnbaum; K G Nelson
Decreased ligand binding to the hepatic glucocorticoid and epidermal growth factor receptors after 2,3,4,7,8-pentachlorodibenzofuran and 1,2,3,4,7,8-hexachlorodibenzofuran treatment of pregnant mice.
Toxicology and applied pharmacology 1989;98(3):454-64.
1989: M W Harris; Linda S Birnbaum
Developmental toxicity of perfluorodecanoic acid in C57BL/6N mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1989;12(3):442-8.
1989: L A Couture; M W Harris; Linda S Birnbaum
Developmental toxicity of 2,3,4,7,8-pentachlorodibenzofuran in the Fischer 344 rat.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1989;12(2):358-66.
1989: D W Brewster; Y B Banks; A M Clark; Linda S Birnbaum
Comparative dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin and three polychlorinated dibenzofurans.
Toxicology and applied pharmacology 1989;97(1):156-66.
1988: D W Brewster; Linda S Birnbaum
Disposition of 1,2,3,7,8-pentachlorodibenzofuran in the rat.
Toxicology and applied pharmacology 1988;95(3):490-8.
1988: Janet J Diliberto; G Usha; Linda S Birnbaum
Disposition of citral in male Fischer rats.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(5):721-7.
1988: D W Brewster; L C Uraih; Linda S Birnbaum
The acute toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4PeCDF) in the male Fischer rat.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1988;11(2):236-49.
1988: D W Brewster; Michael R Elwell; Linda S Birnbaum
Toxicity and disposition of 2,3,4,7,8-pentachlorodibenzofuran (4PeCDF) in the rhesus monkey (Macaca mulatta).
Toxicology and applied pharmacology 1988;93(2):231-46.
1988: G N Rao; Linda S Birnbaum; J J Collins; R W Tennant; L C Skow
Mouse strains for chemical carcinogenicity studies: overview of a workshop.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1988;10(3):385-94.
1988: L A Couture; Michael R Elwell; Linda S Birnbaum
Dioxin-like effects observed in male rats following exposure to octachlorodibenzo-p-dioxin (OCDD) during a 13-week study.
Toxicology and applied pharmacology 1988;93(1):31-46.
1988: Linda S Birnbaum; L A Couture
Disposition of octachlorodibenzo-p-dioxin (OCDD) in male rats.
Toxicology and applied pharmacology 1988;93(1):22-30.
1988: S J Borghoff; S A Stefanski; Linda S Birnbaum
The effect of age on the glucuronidation and toxicity of 4,4'-thiobis(6-t-butyl-m-cresol).
Toxicology and applied pharmacology 1988;92(3):453-66.
1987: Linda S Birnbaum; M W Harris; D D Crawford; R E Morrissey
Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice.
Toxicology and applied pharmacology 1987;91(2):246-55.