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Alan Salama

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Anti-Glomerular Basement Membrane Disease

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Ruth J Pepper; Charles D Pusey; Alan D Salama; Ruth Tarzi; Michael Walsh; Alina Casian; Dimitrios Chanouzas; Lorraine Harper; Mark A Little
Intravenous cyclophosphamide and plasmapheresis in dialysis-dependent ANCA-associated vasculitis.
Ruth J Pepper; Alan D Salama
Classifying and predicting outcomes in ANCA-associated glomerulonephritis.
John Reynolds; Alan D Salama; Jennifer Smith; Susan Tadros; Jonathan Tee; Timothy J Aitman; Jacques Behmoaras; Gurjeet Bhangal; H Terence Cook; Paul R Cook; David J Evans; Charles D Pusey
Genetic susceptibility to experimental autoimmune glomerulonephritis in the Wistar Kyoto rat.

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All Publications

2013: Ruth J Pepper; Charles D Pusey; Alan D Salama; Ruth Tarzi; Michael Walsh; Alina Casian; Dimitrios Chanouzas; Lorraine Harper; Mark A Little
Intravenous cyclophosphamide and plasmapheresis in dialysis-dependent ANCA-associated vasculitis.
Clinical journal of the American Society of Nephrology : CJASN 2013;8(2):219-24.
2012: Ruth J Pepper; Alan D Salama
Classifying and predicting outcomes in ANCA-associated glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(6):2135-7.
2012: John Reynolds; Alan D Salama; Jennifer Smith; Susan Tadros; Jonathan Tee; Timothy J Aitman; Jacques Behmoaras; Gurjeet Bhangal; H Terence Cook; Paul R Cook; David J Evans; Charles D Pusey
Genetic susceptibility to experimental autoimmune glomerulonephritis in the Wistar Kyoto rat.
The American journal of pathology 2012;180(5):1843-51.
2012: Mary-Jane C J Guerry; Lorraine Harper; Paul Brogan; Ian N Bruce; David P D'Cruz; Raashid Luqmani; Charles D Pusey; Alan D Salama; Caroline O S Savage; David G I Scott; Richard Watts; David R W Jayne
Recommendations for the use of rituximab in anti-neutrophil cytoplasm antibody-associated vasculitis.
Rheumatology (Oxford, England) 2012;51(4):634-43.
2012: Anisha Tanna; Alan D Salama; Paul Brookes; Charles D Pusey
Familial granulomatosis with polyangiitis: three cases of this rare disorder in one Indoasian family carrying an identical HLA DPB1 allele.
BMJ case reports 2012;2012():.
2011: Lavnish Joshi; Sue L Lightman; Charles D Pusey; Alan D Salama; Amy Lee Shirodkar; Simon R J Taylor
Rituximab in refractory ophthalmic Wegener's granulomatosis: PR3 titers may predict relapse, but repeat treatment can be effective.
Ophthalmology 2011;118(12):2498-503.
2011: N J Holden; Matthew David Morgan; R J Pepper; Alan D Salama; A Challa; J Gordon; Lorraine Harper; Julie Williams; Caroline O S Savage
ANCA-stimulated neutrophils release BLyS and promote B cell survival: a clinically relevant cellular process.
Annals of the rheumatic diseases 2011;70(12):2229-33.
2011: Nishkantha Arulkumaran; Gill Gaskin; Philip W Ind; Naomi Periselneris; Charles D Pusey; Nicola Strickland; Alan D Salama
Interstitial lung disease and ANCA-associated vasculitis: a retrospective observational cohort study.
Rheumatology (Oxford, England) 2011;50(11):2035-43.
2011: Nicholas Mansfield; Charles D Pusey; Ruth Tarzi; Tom Cairns; H Terence Cook; Megan Griffith; Anne-Marie Habib; Sally Hamour; Jeremy Levy; Alan D Salama
Prolonged disease-free remission following rituximab and low-dose cyclophosphamide therapy for renal ANCA-associated vasculitis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(10):3280-6.
2011: Nishkantha Arulkumaran; Paul Brogan; Lorraine Harper; Susan Jawad; Charles D Pusey; Stuart W Smith; Alan D Salama
Long- term outcome of paediatric patients with ANCA vasculitis.
Pediatric rheumatology online journal 2011;9():12.
2010: Konstantia-Maria Chavele; Luisa Martinez-Pomares; Jan Domin; Samantha Pemberton; Stuart M Haslam; Anne Dell; H Terence Cook; Charles D Pusey; Siamon Gordon; Alan D Salama
Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice.
The Journal of clinical investigation 2010;120(5):1469-78.
2010: Sally Hamour; Alan D Salama; Charles D Pusey
Management of ANCA-associated vasculitis: Current trends and future prospects.
Therapeutics and clinical risk management 2010;6():253-64.
2010: Nicholas M P Annear; H Terence Cook; Mark Atkins; Charles D Pusey; Alan D Salama
Non-hepatitis virus associated mixed essential cryoglobulinemia.
Kidney international 2010;77(2):161-4.
2009: Mark Little; Lucy Smyth; Alan D Salama; Sriparna Mukherjee; Jennifer Smith; Dorian Haskard; Sussan Nourshargh; H Terence Cook; Charles D Pusey
Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis.
The American journal of pathology 2009;174(4):1212-20.
2008: Alan D Salama; H Terence Cook; Charles D Pusey; Ruth J Pepper
A case of treated ANCA-associated vasculitis with recurrent renal failure.
Clinical journal of the American Society of Nephrology : CJASN 2008;3(2):637-45.
2007: Alan D Salama
How high is the risk of ANCA-associated vasculitis recurring after renal transplantation?
Nature clinical practice. Nephrology 2007;3(10):538-9.
2007: Alan D Salama; Karl L Womer; Mohamed H Sayegh
Clinical transplantation tolerance: many rivers to cross.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5419-23.
2005: Sigrid E Sandner; Michael R Clarkson; Alan D Salama; Alberto Sanchez-Fueyo; Christoph Domenig; Antje Habicht; Nader Najafian; Hideo Yagita; Miyuki Azuma; Laurence A Turka; Mohamed H Sayegh
Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3408-15.
2005: Akira Yamada; Alan D Salama; Masayuki Sho; Nader Najafian; Toshiro Ito; John P Forman; Reshma Kewalramani; Sigrid E Sandner; Hiroshi Harada; Michael R Clarkson; Didier A Mandelbrot; Arlene H Sharpe; Hideo Oshima; Hideo Yagita; Geetha Chalasani; Fadi G Lakkis; Hugh Auchincloss; Mohamed H Sayegh
CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1357-64.
2005: Sigrid E Sandner; Michael R Clarkson; Alan D Salama; Alberto Sanchez-Fueyo; Hideo Yagita; Laurence A Turka; Mohamed H Sayegh
Mechanisms of tolerance induced by donor-specific transfusion and ICOS-B7h blockade in a model of CD4+ T-cell-mediated allograft rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(1):31-9.
2004: Tanuja Chitnis; Alan D Salama; Michael J Grusby; Mohamed H Sayegh; Samia J Khoury
Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4260-5.
2003: Alan D Salama; Jeremy Levy
Tolerance and autoimmunity in anti-GBM disease.
Journal of the American Society of Nephrology : JASN 2003;14(11):2988-9.
2003: Alan D Salama; Afzal N Chaudhry; Kathryn A Holthaus; Karen L Mosley; Raghu Kalluri; Mohamed H Sayegh; Robert I Lechler; Charles D Pusey; Liz Lightstone
Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease.
Kidney international 2003;64(5):1685-94.
2003: Nader Najafian; Tanuja Chitnis; Alan D Salama; Bing Zhu; Christina Benou; Xueli Yuan; Michael R Clarkson; Mohamed H Sayegh; Samia J Khoury
Regulatory functions of CD8+CD28- T cells in an autoimmune disease model.
The Journal of clinical investigation 2003;112(7):1037-48.
2003: Sigrid E Sandner; Alan D Salama; Stuart L Houser; Ed Palmer; Laurence A Turka; Mohamed H Sayegh
New TCR transgenic model for tracking allospecific CD4 T-cell activation and tolerance in vivo.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(10):1242-50.
2003: Alan D Salama; Tanuja Chitnis; Jaime Imitola; Mohammed Javeed I Ansari; Hisaya Akiba; Fumihiko Tushima; Miyuki Azuma; Hideo Yagita; Mohamed H Sayegh; Samia J Khoury
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2003;198(1):71-8.
2003: Mohammed Javeed I Ansari; Alan D Salama; Tanuja Chitnis; Rex Smith; Hideo Yagita; Hisaya Akiba; Yamazaki Tomohide; Miyuki Azuma; Hideyuki Iwai; Samia J Khoury; Hugh Auchincloss; Mohamed H Sayegh
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine 2003;198(1):63-9.
2003: Hiroshi Harada; Alan D Salama; Masayuki Sho; Atsushi Izawa; Sigrid E Sandner; Toshiro Ito; Hisaya Akiba; Hideo Yagita; Arlene H Sharpe; Gordon J Freeman; Mohamed H Sayegh
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity.
The Journal of clinical investigation 2003;112(2):234-43.
2003: Alan D Salama; Nader Najafian; Michael R Clarkson; William E Harmon; Mohamed H Sayegh
Regulatory CD25+ T cells in human kidney transplant recipients.
Journal of the American Society of Nephrology : JASN 2003;14(6):1643-51.
2003: Alan D Salama; Xueli Yuan; Ali Nayer; Anil Chandraker; Manabu Inobe; Toshimutsu Uede; Mohamed H Sayegh
Interaction between ICOS-B7RP1 and B7-CD28 costimulatory pathways in alloimmune responses in vivo.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(4):390-5.
2003: Xueli Yuan; Alan D Salama; Victor M Dong; Isabela Schmitt; Nader Najafian; Anil Chandraker; Hisaya Akiba; Hideo Yagita; Mohamed H Sayegh
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2949-55.
2002: Masayuki Sho; Sigrid E Sandner; Nader Najafian; Alan D Salama; Victor M Dong; Akira Yamada; Koji Kishimoto; Hiroshi Harada; Isabela Schmitt; Mohamed H Sayegh
New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs.
Annals of surgery 2002;236(5):667-75.
2002: Masayuki Sho; Akira Yamada; Nader Najafian; Alan D Salama; Hiroshi Harada; Sigrid E Sandner; Alberto Sanchez-Fueyo; Xin Xiao Zheng; Terry B Strom; Mohamed H Sayegh
Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25+ cells, and the alloreactive T cell clone size.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3744-51.
2002: Xueli Yuan; Victor M Dong; Ana J Coito; Ana Maria Waaga; Alan D Salama; Christopher D Benjamin; Mohamed H Sayegh; Anil Chandraker
A novel CD154 monoclonal antibody in acute and chronic rat vascularized cardiac allograft rejection.
Transplantation 2002;73(11):1736-42.
2002: Alan D Salama; Tammy Dougan; Jeremy Levy; H Terence Cook; Steve H Morgan; Sarah Naudeer; Geoff Maidment; Andrew J T George; David Evans; Liz Lightstone; Charles D Pusey
Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;39(6):1162-7.
2002: Alan D Salama; Charles D Pusey
Immunology of anti-glomerular basement membrane disease.
Current opinion in nephrology and hypertension 2002;11(3):279-86.
2002: Akira Yamada; Alan D Salama; Mohamed H Sayegh
The role of novel T cell costimulatory pathways in autoimmunity and transplantation.
Journal of the American Society of Nephrology : JASN 2002;13(2):559-75.
2002: Nader Najafian; Alan D Salama; Eugenia V Fedoseyeva; Gilles Benichou; Mohamed H Sayegh
Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: potential novel assay for prediction of outcomes for renal transplant recipients.
Journal of the American Society of Nephrology : JASN 2002;13(1):252-9.
2001: Masayuki Sho; Alan D Salama; Akira Yamada; Nader Najafian; Mohamed H Sayegh
Physiologic regulation of alloimmune responses in vivo: the role of CTLA4 and TH1/TH2 cytokines.
Transplantation proceedings 2001;33(7-8):3826-8.
2001: Akira Yamada; Alan D Salama; Nader Najafian; Hugh Auchincloss; Mohamed H Sayegh
TNF:TNF-R T-Cell costimulatory pathways in transplantation.
Transplantation proceedings 2001;33(7-8):3070-1.
2001: Alan D Salama; Giuseppe Remuzzi; W E Harmon; Mohamed H Sayegh
Challenges to achieving clinical transplantation tolerance.
The Journal of clinical investigation 2001;108(7):943-8.
2001: Alan D Salama; Jeremy Levy; Liz Lightstone; Charles D Pusey
Goodpasture's disease.
Lancet 2001;358(9285):917-20.
2001: Alan D Salama; Alexandros Delikouras; Charles D Pusey; H Terence Cook; Gurjeet Bhangal; Robert I Lechler; Anthony Dorling
Transplant accommodation in highly sensitized patients: a potential role for Bcl-xL and alloantibody.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2001;1(3):260-9.
2001: Tanuja Chitnis; Nader Najafian; Christina Benou; Alan D Salama; Michael J Grusby; Mohamed H Sayegh; Samia J Khoury
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2001;108(5):739-47.
2001: Alan D Salama; Afzal N Chaudhry; J J Ryan; E Eren; Jeremy Levy; Charles D Pusey; Liz Lightstone; R I Lechler
In Goodpasture's disease, CD4(+) T cells escape thymic deletion and are reactive with the autoantigen alpha3(IV)NC1.
Journal of the American Society of Nephrology : JASN 2001;12(9):1908-15.
2001: Akira Yamada; Koji Kishimoto; Victor M Dong; Masayuki Sho; Alan D Salama; Natalie Anosova; Gilles Benichou; Didier A Mandelbrot; Arlene H Sharpe; Laurence A Turka; Hugh Auchincloss; Mohamed H Sayegh
CD28-independent costimulation of T cells in alloimmune responses.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):140-6.