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Moin Saleem

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M Amjad Khan; Paula Murphy; A V Ramanan; Moin A Saleem
Renal hypertension: an unusual cause for a common problem.
Moin A Saleem
New developments in steroid-resistant nephrotic syndrome.
Jessica J Harris; HeeGyung Kang; Hugh J McCarthy; Lan Ni; Gavin I Welsh; Jack F Wetzels; Matthew Wherlock; Moin A Saleem
Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1.

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All Publications

2013: M Amjad Khan; Paula Murphy; A V Ramanan; Moin A Saleem
Renal hypertension: an unusual cause for a common problem.
European journal of pediatrics 2013;172(5):711-2.
2013: Moin A Saleem
New developments in steroid-resistant nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) 2013;28(5):699-709.
2013: Jessica J Harris; HeeGyung Kang; Hugh J McCarthy; Lan Ni; Gavin I Welsh; Jack F Wetzels; Matthew Wherlock; Moin A Saleem
Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1.
The Journal of pathology 2013;229(5):660-71.
2013: Hugh J McCarthy; Milos Ognjanovic; Moin A Saleem; Manish D Sinha; Nicholas J A Webb; Gavin I Welsh; Matt Wherlock; Margaret M Williams; Agnieszka Bierzynska; Martin Christian; Sally Feather; Rodney David Gilbert; Shivaram Hegde; Caroline Jones; Larissa Kerecuk; Ania Koziell; Leah Krischock; Stephen Marks
Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.
Clinical journal of the American Society of Nephrology : CJASN 2013;8(4):637-48.
2013: Mervi Ristola; Moin A Saleem; Toshibumi Shimokawa; Jukka Tienari; Satu Arpiainen; Harry Holthöfer; Chisei Ra; Sanna Lehtonen
Regulation of nephrin gene by the Ets transcription factor, GA-binding protein.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2013;28(4):846-55.
2013: Tarak Srivastava; Kok-Hooi Yew; Uri S Alon; Patricia A Cudmore; R Scott Duncan; Alexander Kats; Ellen T McCarthy; Moin A Saleem; Mukut Sharma; Ram Sharma; Christopher J Harrison
LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: changes in TLR profile.
Journal of cell communication and signaling 2013;7(1):49-60.
2013: Partab Rai; Moin A Saleem; Kamesh R Ayasolla; Amrita K Chawla; Mohammad Husain; Dileep Kumar; Ashwani Malhotra; Peter W Mathieson; Shresh Pathak; Andrei Plagov; Pravin C Singhal
Rapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN.
Experimental and molecular pathology 2013;94(1):255-61.
2013: Raymond Tan; Pranai Tandon; Poornima Upadhya; Mohammad Husain; Liming Luan; Ashwani Malhotra; Peter W Mathieson; Hitesh Patni; Moin A Saleem; Divya Salhan; Bipin Sharma; Pravin C Singhal
Nef interaction with actin compromises human podocyte actin cytoskeletal integrity.
Experimental and molecular pathology 2013;94(1):51-7.
2013: Xiqian Lan; Rivka Lederman; Ashwani Malhotra; Peter W Mathieson; Partab Rai; Moin A Saleem; Nirupama Chandel; Kang Cheng; John T Crosson; Kalpna Gupta; Mohammad Husain; Pravin C Singhal
Morphine induces albuminuria by compromising podocyte integrity.
PloS one 2013;8(3):e55748.
2013: Daniel E Henao; Angela Patricia Cadavid; Moin A Saleem
Exogenous vascular endothelial growth factor supplementation can restore the podocyte barrier-forming capacity disrupted by sera of preeclamptic women.
The journal of obstetrics and gynaecology research 2013;39(1):46-52.
2012: Himanshu Vashistha; Anna Wilk; Pier Giuseppe Pelicci; Francesca Peruzzi; Krzysztof Reiss; Moin A Saleem; Surya Seshan; Pravin C Singhal; Oliver Smithies; Luis Delvalle; Marco Giorgio; Mohammad Husain; Masao Kakoki; Hyung-Suk Kim; Cyril Kuriakose; Ashwani Malhotra; Peter Mathieson; Leonard G Meggs
Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.
American journal of physiology. Renal physiology 2012;303(12):F1629-40.
2012: Moin A Saleem
The phenomenon of focal segmental glomerulosclerosis post-transplantation--a one-hit wonder?
Pediatric nephrology (Berlin, Germany) 2012;27(12):2163-6.
2012: Sadie C Slater; Kate Uttridge; Gavin I Welsh; Paul A Cahill; Peter W Mathieson; Raina D Ramnath; Moin A Saleem; Simon C Satchell
Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes.
The international journal of biochemistry & cell biology 2012;44(9):1482-90.
2012: Katsuyuki Tanabe; Christopher J Rivard; Moin A Saleem; George F Schreiner; Richard J Johnson; Wataru Kitagawa; Jelena Klawitter; Miguel A Lanaspa; Hirofumi Makino; Peter W Mathieson; Makoto Miyazaki; Takahiko Nakagawa
Nicorandil as a novel therapy for advanced diabetic nephropathy in the eNOS-deficient mouse.
American journal of physiology. Renal physiology 2012;302(9):F1151-60.
2012: Mervi Ristola; Moin A Saleem; Satu Arpiainen; Harry Holthöfer; Sanna Lehtonen
Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(5):1737-45.
2012: Simran Khurana; Minh Lam; Yu Liu; Peter W Mathieson; Moin A Saleem; Yu-Ting Su; Xuan Zhao; Leslie A Bruggeman; Sharmistha Chakraborty; Hung-Ying Kao
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.
The Journal of biological chemistry 2012;287(15):12027-35.
2012: Claire Rigothier; Jean Ripoche; Moin A Saleem; Gavin I Welsh; Patrick Auguste; Colette Deminière; Sébastien Lepreux; Peter W Mathieson; Christian Combe
IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro.
PloS one 2012;7(5):e37695.
2012: Lindsay Keir; Feike van Moorsel; Moin A Saleem; Anna Richards
Beware renal adverse effects of anti-vascular endothelial growth factor treatment.
BMJ (Clinical research ed.) 2012;344():e3838.
2012: Michiko Shimada; David T Wymer; Hideaki Yamabe; Eduardo H Garin; Takuji Ishimoto; Miguel A Lanaspa; Pui Y Lee; Peter W Mathieson; Christopher J Rivard; Carlos A Roncal-Jimenez; Moin A Saleem; Richard J Johnson
Toll-like receptor 3 ligands induce CD80 expression in human podocytes via an NF-κB-dependent pathway.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(1):81-9.
2011: Yoichi Oshima; Susan E Quaggin; Mariyo Sakoda; Moin A Saleem; Ge-Hong Sun-Wada; Minoru Takemoto; Yoh Wada; Taketo Yamada; Kenichiro Kinouchi; Asako Kurauchi-Mito; Hideaki Kurosawa; Tatsuya Narita; Kanako Bokuda; Atsuhiro Ichihara; Hiroshi Itoh
Prorenin receptor is essential for normal podocyte structure and function.
Journal of the American Society of Nephrology : JASN 2011;22(12):2203-12.
2011: Ramadan M Sarrab; Gavin I Welsh; Matthew D Wherlock; Rachel Lennon; Lan Ni; Moin A Saleem
Establishment of conditionally immortalized human glomerular mesangial cells in culture, with unique migratory properties.
American journal of physiology. Renal physiology 2011;301(5):F1131-8.
2011: Shuang Zhao; Gregory Coates; Lynn J Groome; Yang Gu; Peter W Mathieson; Moin A Saleem; Yuping Wang
Altered nephrin and podoplanin distribution is associated with disturbed polarity protein PARD-3 and PARD-6 expressions in podocytes from preeclampsia.
Reproductive sciences (Thousand Oaks, Calif.) 2011;18(8):772-80.
2011: Maria D Sanchez-Niño; Ana B Sanz; Susana Carrasco; Moin A Saleem; Peter W Mathieson; José M Valdivielso; Marta Ruiz-Ortega; jesus egido; Alberto Ortiz
Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(6):1797-802.
2011: Britta George; Beate Vollenbröker; Moin A Saleem; Tobias B Huber; Hermann Pavenstädt; Thomas Weide
GSK3β inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility.
American journal of physiology. Renal physiology 2011;300(5):F1152-62.
2011: Hong Qu; Yizeng Tu; Xiaohua Shi; Hannu Larjava; Moin A Saleem; Sanford J Shattil; Koichi Fukuda; Jun Qin; Matthias Kretzler; Chuanyue Wu
Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins.
Journal of cell science 2011;124(Pt 6):879-91.
2011: Betty S van der Veen; Min Chen; Ralf Müller; Mirjan M van Timmeren; Arjen H Petersen; Patrice A Lee; Simon C Satchell; Peter W Mathieson; Moin A Saleem; Coen A Stegeman; Jochen Zwerina; Grietje Molema; Peter Heeringa
Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo.
Annals of the rheumatic diseases 2011;70(2):356-65.
2011: Thaneas Prabakaran; Moin A Saleem; Søren S Sørensen; Pierre J Verroust; Ulla Feldt-Rasmussen; Jakob V Larsen; Rikke Nielsen; Claus M Petersen; Erik I Christensen
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease.
PloS one 2011;6(9):e25065.
2011: Sadie C Slater; Bo Su; Gavin I Welsh; Xuejun Wen; Daming Zhang; Vince Beachley; Thomas Hayes; Peter W Mathieson; Moin A Saleem; Simon C Satchell
An in vitro model of the glomerular capillary wall using electrospun collagen nanofibres in a bioartificial composite basement membrane.
PloS one 2011;6(6):e20802.
2011: Hugh J McCarthy; Moin A Saleem
Genetics in clinical practice: nephrotic and proteinuric syndromes.
Nephron. Experimental nephrology 2011;118(1):e1-8.
2011: Richard J M Coward; Moin A Saleem
Podocytes as a target of insulin.
Current diabetes reviews 2011;7(1):22-7.
2010: Shaun A Summers; Betty S van der Veen; Kim M O'Sullivan; Poh-Yi Gan; Joshua D Ooi; Peter Heeringa; Simon C Satchell; Peter W Mathieson; Moin A Saleem; Kumar Visvanathan; Stephen R Holdsworth; A Richard Kitching
Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis.
Kidney international 2010;78(12):1263-74.
2010: Gavin I Welsh; Lorna J Hale; Vera Eremina; Marie Jeansson; Yoshiro Maezawa; Rachel Lennon; Deborah A Pons; Rachel J Owen; Simon C Satchell; Mervyn J Miles; Christopher J Caunt; Craig A McArdle; Hermann Pavenstädt; Jeremy M Tavaré; Andrew M Herzenberg; C Ronald Kahn; Peter W Mathieson; Susan E Quaggin; Moin A Saleem; Richard J M Coward
Insulin signaling to the glomerular podocyte is critical for normal kidney function.
Cell metabolism 2010;12(4):329-40.
2010: Takayuki Matsumoto; Sonja Hess; Hiroshi Kajiyama; Toru Sakairi; Moin A Saleem; Peter W Mathieson; Yoshihisa Nojima; Jeffrey B Kopp
Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product.
American journal of physiology. Renal physiology 2010;299(4):F776-84.
2010: Anusha G Edwards; Hugh McCarthy; Justin D Morgan; Moin A Saleem
Paediatric non-heart-beating renal transplantation.
Archives of disease in childhood 2010;95(10):843-4.
2010: Fiona Wu; Moin A Saleem; Nicole B Kampik; Timothy Satchwell; Rosalind C Williamson; Simone M Blattner; Lan Ni; Tibor Toth; Graham White; Mark T Young; Mark D Parker; Seth L Alper; Carsten A Wagner; Ashley M Toye
Anion exchanger 1 interacts with nephrin in podocytes.
Journal of the American Society of Nephrology : JASN 2010;21(9):1456-67.
2010: Chun-Liang Lin; Feng-Sheng Wang; Yen-Chen Hsu; Cheng-Nan Chen; Min-Jen Tseng; Moin A Saleem; Pey-Jium Chang; Jeng-Yi Wang
Modulation of notch-1 signaling alleviates vascular endothelial growth factor-mediated diabetic nephropathy.
Diabetes 2010;59(8):1915-25.
2010: Rebecca Rachael Foster; Gavin I Welsh; Simon C Satchell; Robin D Marlow; Mathew D Wherlock; Debora Pons; Peter W Mathieson; David O Bates; Moin A Saleem
Functional distinctions in cytosolic calcium regulation between cells of the glomerular filtration barrier.
Cell calcium 2010;48(1):44-53.
2010: Chunsun Dai; Moin A Saleem; Lawrence B Holzman; Peter Mathieson; Youhua Liu
Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria.
Kidney international 2010;77(11):962-73.
2010: Mariyo Sakoda; Atsuhiro Ichihara; Asako Kurauchi-Mito; Tatsuya Narita; Kenichiro Kinouchi; Kanako Murohashi-Bokuda; Moin A Saleem; Akira Nishiyama; Fumiaki Suzuki; Hiroshi Itoh
Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes.
American journal of hypertension 2010;23(5):575-80.
2010: Gavin I Welsh; Moin A Saleem
Nephrin-signature molecule of the glomerular podocyte?
The Journal of pathology 2010;220(3):328-37.
2010: Martijn J G Wilmer; Moin A Saleem; Rosalinde Masereeuw; Lan Ni; Thea J van der Velden; Frans G M Russel; Peter W Mathieson; Leo A Monnens; Lambertus P van den Heuvel; Elena N Levtchenko
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters.
Cell and tissue research 2010;339(2):449-57.
2010: Caroline Platt; Carol Inward; Mary McGraw; Jan Dudley; Jane Tizard; Christine Burren; Moin A Saleem
Middle-term use of Cinacalcet in paediatric dialysis patients.
Pediatric nephrology (Berlin, Germany) 2010;25(1):143-8.
2010: Daniel E Henao; Moin A Saleem; Angela Patricia Cadavid
Glomerular disturbances in preeclampsia: disruption between glomerular endothelium and podocyte symbiosis.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2010;29(1):10-20.
2009: Rachel Lennon; Deborah Pons; Matthew A Sabin; Christina Wei; Julian P Shield; Richard J Coward; Jeremy M Tavaré; Peter W Mathieson; Moin A Saleem; Gavin I Welsh
Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(11):3288-96.
2009: Shitij Arora; Mohammad Husain; Dileep Kumar; Hitesh Patni; Shresh Pathak; Devi Mehrotra; Vivek Kathi Reddy; Lalit Rajeev Reddy; Divya Salhan; Anju Yadav; Peter W Mathieson; Moin A Saleem; Praveen N Chander; Pravin Singhal
Human immunodeficiency virus downregulates podocyte apoE expression.
American journal of physiology. Renal physiology 2009;297(3):F653-61.
2009: Ulf Nilsson; Kjell Hultenby; Sara Ek; Jonas Sjölund; Håkan Axelson; Karin Jirström; Moin A Saleem; Kristina Nilsson; Martin E Johansson
CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(7):2038-44.
2009: Mohammad Husain; Leonard G Meggs; Himanshu Vashistha; Sonia Simoes; Kevin O Griffiths; Dileep Kumar; Joanna Mikulak; Peter W Mathieson; Moin A Saleem; Luis Del Valle; Sergio Pina-Oviedo; Jin Ying Wang; Surya V Seshan; Ashwani Malhotra; Krzysztof Reiss; Pravin Singhal
Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis.
The Journal of biological chemistry 2009;284(24):16648-58.
2009: Alice C N Brown; Dalila Hallouane; William J Mawby; Fiona E Karet; Moin A Saleem; Alexander J Howie; Ashley M Toye
RhCG is the major putative ammonia transporter expressed in the human kidney, and RhBG is not expressed at detectable levels.
American journal of physiology. Renal physiology 2009;296(6):F1279-90.
2009: Hua-Xin Gao; Sean R Campbell; Linda C Burkly; Aniela Jakubowski; Irene Jarchum; Bernhard Banas; Moin A Saleem; Peter W Mathieson; Joan W Berman; Jennifer S Michaelson; Chaim Putterman
TNF-like weak inducer of apoptosis (TWEAK) induces inflammatory and proliferative effects in human kidney cells.
Cytokine 2009;46(1):24-35.
2009: Rebecca R Foster; Maryam A H Zadeh; Gavin I Welsh; Simon C Satchell; Yi Ye; Peter W Mathieson; David O Bates; Moin A Saleem
Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells.
Cell calcium 2009;45(4):384-90.
2009: Mitchell A Psotka; Fumiko Obata; Glynis L Kolling; Lisa K Gross; Moin A Saleem; Simon C Satchell; Peter W Mathieson; Tom Obrig
Shiga toxin 2 targets the murine renal collecting duct epithelium.
Infection and immunity 2009;77(3):959-69.
2009: Beate Vollenbröker; Britta George; Maria Wolfgart; Moin A Saleem; Hermann Pavenstädt; Thomas Weide
mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes.
American journal of physiology. Renal physiology 2009;296(2):F418-26.
2009: Maria-Dolores Sanchez-Niño; Ana Belen Sanz; Pekka Ihalmo; Markus Lassila; Harry Holthofer; Sergio Mezzano; Claudio Aros; Per-Henrik Groop; Moin A Saleem; Peter W Mathieson; Robyn G Langham; Matthias Kretzler; Viji Nair; Kevin V Lemley; Robert G Nelson; Eero Mervaala; Deborah Mattinzoli; Maria Pia Rastaldi; Marta Ruiz-Ortega; Jose Luis Martin-Ventura; Jesus Egido; alberto ortiz
The MIF receptor CD74 in diabetic podocyte injury.
Journal of the American Society of Nephrology : JASN 2009;20(2):353-62.
2009: Mervi Ristola; Satu Arpiainen; Moin A Saleem; Peter W Mathieson; Gavin I Welsh; Sanna Lehtonen; Harry Holthöfer
Regulation of Neph3 gene in podocytes--key roles of transcription factors NF-kappaB and Sp1.
BMC molecular biology 2009;10():83.
2009: Nicholas J A Webb; Sylwester Prokurat; Karel Vondrak; Alan R Watson; David A Hughes; Stephen D Marks; Nadeem E Moghal; Maggie M Fitzpatrick; David V Milford; Moin A Saleem; Caroline A Jones; Styrbjorn Friman; Rita Van Damme-Lombaerts; Francoise Janssen; Clare Hamer; Sarah Rhodes
Multicentre prospective randomised trial of tacrolimus, azathioprine and prednisolone with or without basiliximab: two-year follow-up data.
Pediatric nephrology (Berlin, Germany) 2009;24(1):177-82.
2008: Rachel Lennon; Anurag Singh; Gavin I Welsh; Richard J M Coward; Simon C Satchell; Lan Ni; Peter W Mathieson; Winston W Bakker; Moin A Saleem
Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes.
Journal of the American Society of Nephrology : JASN 2008;19(11):2140-9.
2008: Dawid Nowak; Jeanette Woolard; Elianna Mohamed Amin; Olga Konopatskaya; Moin A Saleem; Amanda J Churchill; Michael R Ladomery; Steven J Harper; David O Bates
Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors.
Journal of cell science 2008;121(Pt 20):3487-95.
2008: Moin A Saleem; Jiri Zavadil; Maryse Bailly; Karen McGee; Ian R Witherden; Hermann Pavenstadt; Hsianghao Hsu; Julia Sanday; Simon C Satchell; Rachel Lennon; Lan Ni; Erwin P Bottinger; Peter Mundel; Peter W Mathieson
The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells.
American journal of physiology. Renal physiology 2008;295(4):F959-70.
2008: Kerstin Duning; Eva-Maria Schurek; Marc Schlüter; Michael Bayer; Hans-Christian Reinhardt; Albrecht Schwab; Liliana Schaefer; Thomas Benzing; Bernhard Schermer; Moin A Saleem; Tobias B Huber; Sebastian Bachmann; Joachim Kremerskothen; Thomas Weide; Hermann Pavenstädt
KIBRA modulates directional migration of podocytes.
Journal of the American Society of Nephrology : JASN 2008;19(10):1891-903.
2008: Avril Morrison; Rebecca L Viney; Moin A Saleem; Michael R Ladomery
New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes.
American journal of physiology. Renal physiology 2008;295(1):F12-7.
2008: Kar Neng Lai; Joseph C K Leung; Loretta Y Y Chan; Moin A Saleem; Peter W Mathieson; Fernand M Lai; Sydney C W Tang
Activation of podocytes by mesangial-derived TNF-alpha: glomerulo-podocytic communication in IgA nephropathy.
American journal of physiology. Renal physiology 2008;294(4):F945-55.
2008: Corina M Borza; Dorin-Bogdan Borza; Vadim Pedchenko; Moin A Saleem; Peter W Mathieson; Yoshikazu Sado; Heather M Hudson; Ambra Pozzi; Juan Saus; Dale R Abrahamson; Roy Zent; Billy G Hudson
Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network.
Journal of the American Society of Nephrology : JASN 2008;19(4):677-84.
2008: Daniel E Henao; Luis F Arias; Peter W Mathieson; Lan Ni; Gavin I Welsh; Julio C Bueno; Bernardo Agudelo; Angela Patricia Cadavid; Moin A Saleem
Preeclamptic sera directly induce slit-diaphragm protein redistribution and alter podocyte barrier-forming capacity.
Nephron. Experimental nephrology 2008;110(3):e73-81.
2007: Simon C Satchell; Olena Buchatska; Sarah B Khan; Gurjeet Bhangal; Candida H Tasman; Moin A Saleem; Darren P Baker; Roy R Lobb; Jennifer Smith; H Terence Cook; Peter W Mathieson; Charles D Pusey
Interferon-beta reduces proteinuria in experimental glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2007;18(11):2875-84.
2007: Kazutomo Sawai; Masashi Mukoyama; Kiyoshi Mori; Masato Kasahara; Masao Koshikawa; Hideki Yokoi; Tetsuro Yoshioka; Yoshihisa Ogawa; Akira Sugawara; Hiroyuki Nishiyama; Shigehito Yamada; Takashi Kuwahara; Moin A Saleem; Kohei Shiota; Osamu Ogawa; Mikiya Miyazato; Kenji Kangawa; Kazuwa Nakao
Expression of CCN1 (CYR61) in developing, normal, and diseased human kidney.
American journal of physiology. Renal physiology 2007;293(4):F1363-72.
2007: Minola Manea; AnnCharlotte Kristoffersson; Reinhard Schneppenheim; Moin A Saleem; Peter W Mathieson; Matthias Mörgelin; Peter Björk; Lars Holmberg; Diana Karpman
Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura.
British journal of haematology 2007;138(5):651-62.
2007: Gaddameedi R Reddy; Mary J Pushpanathan; Richard F Ransom; Lawrence B Holzman; Frank C Brosius III; Maria Diakonova; Peter Mathieson; Moin A Saleem; Edward O List; John J Kopchick; Stuart J Frank; Ramkumar Menon
Identification of the glomerular podocyte as a target for growth hormone action.
Endocrinology 2007;148(5):2045-55.
2007: Daniel E Henao; Peter W Mathieson; Moin A Saleem; Julio C Bueno; Angela Cadavid
A novel renal perspective of preeclampsia: a look from the podocyte.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(5):1477.
2007: Richard J M Coward; Gavin I Welsh; Ania Koziell; Sagair Hussain; Rachel Lennon; Lan Ni; Jeremy M Tavaré; Peter W Mathieson; Moin A Saleem
Nephrin is critical for the action of insulin on human glomerular podocytes.
Diabetes 2007;56(4):1127-35.
2007: Rebecca L Viney; Avril Morrison; Lambert P van den Heuvel; Lan Ni; Peter W Mathieson; Moin A Saleem; Michael R Ladomery
A proteomic investigation of glomerular podocytes from a Denys-Drash syndrome patient with a mutation in the Wilms tumour suppressor gene WT1.
Proteomics 2007;7(5):804-15.
2007: Jeanette Eyre; Kyriakos Ioannou; Blair D Grubb; Moin A Saleem; Peter W Mathieson; Nigel J Brunskill; Erik I Christensen; Peter S Topham
Statin-sensitive endocytosis of albumin by glomerular podocytes.
American journal of physiology. Renal physiology 2007;292(2):F674-81.
2006: A Björnson Granqvist; K Ebefors; Moin A Saleem; P W Mathieson; Borje Haraldsson; Ulf Nilsson
Podocyte proteoglycan synthesis is involved in the development of nephrotic syndrome.
American journal of physiology. Renal physiology 2006;291(4):F722-30.
2006: C-Y Xing; Moin A Saleem; Richard J M Coward; Lan Ni; Ian R Witherden; Peter W Mathieson
Direct effects of dexamethasone on human podocytes.
Kidney international 2006;70(6):1038-45.
2006: Kazutomo Sawai; Masashi Mukoyama; Kiyoshi Mori; Hideki Yokoi; Masao Koshikawa; Tetsuro Yoshioka; Ryuji Takeda; Akira Sugawara; Takashi Kuwahara; Moin A Saleem; Osamu Ogawa; Kazuwa Nakao
Redistribution of connexin43 expression in glomerular podocytes predicts poor renal prognosis in patients with type 2 diabetes and overt nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(9):2472-7.
2006: Rebecca R Foster; Simon C Satchell; J Seckley; M S Emmett; KD Joory; C Y Xing; Moin A Saleem; Peter W Mathieson; David O Bates; Steven J Harper
VEGF-C promotes survival in podocytes.
American journal of physiology. Renal physiology 2006;291(1):F196-207.
2006: Simon C Satchell; Candida H Tasman; A Singh; Lan Ni; J Geelen; C J von Ruhland; M J O'Hare; Moin A Saleem; L P van den Heuvel; Peter W Mathieson
Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF.
Kidney international 2006;69(9):1633-40.
2006: Clemens D Cohen; Andreas Klingenhoff; Anissa Boucherot; Almut Nitsche; Anna Henger; Bodo Brunner; Holger Schmid; Monika Merkle; Moin A Saleem; Klaus-Peter Koller; Thomas Werner; Hermann-Josef Gröne; Peter J Nelson; Matthias Kretzler
Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5682-7.
2006: Max C Liebau; D Lang; J Böhm; N Endlich; Martin J Bek; Ian R Witherden; Peter W Mathieson; Moin A Saleem; Hermann Pavenstädt; Karl-Georg Fischer
Functional expression of the renin-angiotensin system in human podocytes.
American journal of physiology. Renal physiology 2006;290(3):F710-9.
2006: Joanna Marszal; Moin A Saleem
The bioactivity of plasma factors in focal segmental glomerulosclerosis.
Nephron. Experimental nephrology 2006;104(1):e1-5.
2005: Shuyu Ren; Cuiyan Xin; Karl-Friedrich Beck; Moin A Saleem; Peter Mathieson; Hermann Pavenstädt; Josef Pfeilschifter; Andrea Huwiler
PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism.
Biochemical and biophysical research communications 2005;338(4):1818-24.
2005: Richard J M Coward; Gavin I Welsh; Jing Yang; Candida H Tasman; Rachel Lennon; Ania Koziell; Simon C Satchell; Geoffrey D Holman; Dontscho Kerjaschki; Jeremy M Tavaré; Peter W Mathieson; Moin A Saleem
The human glomerular podocyte is a novel target for insulin action.
Diabetes 2005;54(11):3095-102.
2005: Vadim Pedchenko; Sergei V Chetyrkin; Peale Chuang; Amy-Joan L Ham; Moin A Saleem; Peter W Mathieson; Billy G Hudson; Paul A Voziyan
Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy.
Diabetes 2005;54(10):2952-60.
2005: Bart Janssen; Daniela Hohenadel; Paul T Brinkkoetter; Verena Peters; Nina Rind; Christine Fischer; Ivan Rychlik; Marie Cerna; Marianna Romzova; Emile de Heer; Hans Baelde; Stephan J L Bakker; Mahmoud Zirie; Eric Rondeau; Peter Mathieson; Moin A Saleem; Jochen Meyer; Hannes Köppel; Sibylle Sauerhoefer; Claus R Bartram; Peter Nawroth; Hans-Peter Hammes; Benito A Yard; Johannes Zschocke; Fokko J van der Woude
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.
Diabetes 2005;54(8):2320-7.
2005: Clemens D Cohen; Peter P Doran; Simone M Blattner; Monika Merkle; Guo Q Wang; Holger Schmid; Peter W Mathieson; Moin A Saleem; Anna Henger; Maria Pia Rastaldi; Matthias Kretzler
Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor.
Journal of the American Society of Nephrology : JASN 2005;16(7):1958-65.
2005: Richard J M Coward; Rebecca R Foster; David Patton; Lan Ni; Rachel Lennon; David O Bates; Steven J Harper; Peter W Mathieson; Moin A Saleem
Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes.
Journal of the American Society of Nephrology : JASN 2005;16(3):629-37.
2005: Rebecca R Foster; Moin A Saleem; Peter W Mathieson; David O Bates; Steven J Harper
Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes.
American journal of physiology. Renal physiology 2005;288(1):F48-57.
2004: Michael J Morton; Katie Hutchinson; Peter W Mathieson; Ian R Witherden; Moin A Saleem; Malcolm Hunter
Human podocytes possess a stretch-sensitive, Ca2+-activated K+ channel: potential implications for the control of glomerular filtration.
Journal of the American Society of Nephrology : JASN 2004;15(12):2981-7.
2004: Janette C Cansick; Rachel Lennon; Carole Cummins; Alexander J Howie; Mary McGraw; Moin A Saleem; E Jane Tizard; Sally-Anne Hulton; David V Milford; C Mark Taylor
Prognosis, treatment and outcome of childhood mesangiocapillary (membranoproliferative) glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(11):2769-77.
2003: Tobias B Huber; Matias Simons; Björn Hartleben; Leonie Sernetz; Miriam Schmidts; Enken Gundlach; Moin A Saleem; Gerd Walz; Thomas Benzing
Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains.
Human molecular genetics 2003;12(24):3397-405.
2003: Rebecca R Foster; Rachel Hole; Karen Anderson; Simon C Satchell; Richard J M Coward; Peter W Mathieson; David Gillatt; Moin A Saleem; David O Bates; Steven J Harper
Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes.
American journal of physiology. Renal physiology 2003;284(6):F1263-73.
2003: Moin A Saleem
Urine--a mirror of the (glomerular) soul?
Nephron. Clinical practice 2003;95(3):c75-6.
2003: Moin A Saleem
Biology of the human podocyte.
Nephron. Experimental nephrology 2003;95(3):e87-92.
2002: Moin A Saleem; Lan Ni; Ian R Witherden; Karl Tryggvason; Vesa Ruotsalainen; Peter Mundel; Peter W Mathieson
Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation.
The American journal of pathology 2002;161(4):1459-66.
2002: Tobias B Huber; Hans Christian Reinhardt; Markus Exner; Jan A Burger; Dontscho Kerjaschki; Moin A Saleem; Hermann Pavenstädt
Expression of functional CCR and CXCR chemokine receptors in podocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6244-52.
2002: Moin A Saleem; Michael J O'Hare; Jochen Reiser; Richard J M Coward; Carol D Inward; Timothy Farren; Chang Ying Xing; Lan Ni; Peter W Mathieson; Peter Mundel
A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.
Journal of the American Society of Nephrology : JASN 2002;13(3):630-8.
2002: Simon C Satchell; Steven J Harper; John E Tooke; Dontscho Kerjaschki; Moin A Saleem; Peter W Mathieson
Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor.
Journal of the American Society of Nephrology : JASN 2002;13(2):544-50.