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Elizabeth Birzin
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
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Research Profile (preview)
Chemicals & Drugs
Concepts & Ideas
Living Beings
Anatomy
Genes & Molecular Sequences
Phenomena
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Network (preview)
39
Rohrer, Susan
28
Schaeffer, James
26
Hammond, Milton
20
Chan, Wanda
17
Mosley, Ralph
16
DiNinno, Frank
15
Hayes, Edward
12
Blizzard, Timothy
12
Yang, Yi Tien
11
Pai, Lee-Yuh
10
DaSilva, Carolyn
9
Kim, Seongkon
8
Morgan, Jerry
7
Patchett, Arthur
6
Wu, Jane
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All Publications
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2009: Opas Evan E; Scafonas Angela; Nantermet Pascale V; Wilkening Robert R; Birzin Elizabeth T; Wilkinson Hilary; Colwell Lawrence F; Schaeffer James M; Towler Dwight A; Rodan Gideon A; Schmidt Azriel
Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand.
Maturitas 2009;64(1):46-51.
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2008: Scafonas Angela; Reszka Alfred A; Kimmel Donald B; Hou Xiaoli Shirley; Su Qin; Birzin Elizabeth T; Kim Seongkon; Chen Helen Y; Tan Qiang; Roher Susan P; Dininno Frank; Hammond Milton L; Rodan Gideon A; Towler Dwight A; Schmidt Azriel
Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus.
The Journal of steroid biochemistry and molecular biology 2008;110(3-5):197-206.
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2007: Blizzard Timothy A; Gude Candido; Morgan Jerry D; Chan Wanda; Birzin Elizabeth T; Mojena Marina; Tudela Consuelo; Chen Fang; Knecht Kristin; Su Qin; Kraker Bryan; Mosley Ralph T; Holmes Mark A; Rohrer Susan P; Hammond Milton L
Androstene-3,5-dienes as ER-beta selective SERMs.
Bioorganic & medicinal chemistry letters 2007;17(22):6295-8.
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2007: Blizzard Timothy A; Gude Candido; Chan Wanda; Birzin Elizabeth T; Mojena Marina; Tudela Consuelo; Chen Fang; Knecht Kristin; Su Qin; Kraker Bryan; Holmes Mark A; Rohrer Susan P; Hammond Milton L
Bridged androstenediol analogs as ER-beta selective SERMs.
Bioorganic & medicinal chemistry letters 2007;17(10):2944-8.
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2007: Dykstra Kevin D; Guo Liangqin; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Hayes Edward C; DaSilva Carolyn A; Pai Lee-Yuh; Mosley Ralph T; Kraker Bryan; Fitzgerald Paula M D; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha.
Bioorganic & medicinal chemistry letters 2007;17(8):2322-8.
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2006: Strowski Mathias Z; Cashen Doreen E; Birzin Elizabeth T; Yang Lihu; Singh Vandana; Jacks Thomas M; Nowak Krzysztof W; Rohrer Susan P; Patchett Arthur A; Smith Roy G; Schaeffer James M
Antidiabetic activity of a highly potent and selective nonpeptide somatostatin receptor subtype-2 agonist.
Endocrinology 2006;147(10):4664-73.
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2006: Wildonger Kenneth J; Ratcliffe Ronald W; Mosley Ralph T; Hammond Milton L; Birzin Elizabeth T; Rohrer Susan P
Tetrahydrofluorenones with conformationally restricted side chains as selective estrogen receptor beta ligands.
Bioorganic & medicinal chemistry letters 2006;16(17):4462-6.
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2006: Parker Dann L; Meng Dongfang; Ratcliffe Ronald W; Wilkening Robert R; Sperbeck Donald M; Greenlee Mark L; Colwell Lawrence F; Lambert Sherrie; Birzin Elizabeth T; Frisch Katalin; Rohrer Susan P; Nilsson Stefan; Thorsell Ann-Gerd; Hammond Milton L
Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists.
Bioorganic & medicinal chemistry letters 2006;16(17):4652-6.
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2006: Wilkening R R; Ratcliffe R W; Fried A K; Meng D; Sun W; Colwell L; Lambert S; Greenlee M; Nilsson S; Thorsell A; Mojena M; Tudela C; Frisch K; Chan W; Birzin E T; Rohrer S P; Hammond M L
Estrogen receptor beta-subtype selective tetrahydrofluorenones: use of a fused pyrazole as a phenol bioisostere.
Bioorganic & medicinal chemistry letters 2006;16(15):3896-901.
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2006: Wilkening R R; Ratcliffe R W; Tynebor E C; Wildonger K J; Fried A K; Hammond M L; Mosley R T; Fitzgerald P M D; Sharma N; McKeever B M; Nilsson S; Carlquist M; Thorsell A; Locco L; Katz R; Frisch K; Birzin E T; Wilkinson H A; Mitra S; Cai S; Hayes E C; Schaeffer J M; Rohrer S P
The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands.
Bioorganic & medicinal chemistry letters 2006;16(13):3489-94.
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2006: Sun Wanying; Cama Lovji D; Birzin Elizabeth T; Warrier Sudha; Locco Louis; Mosley Ralph; Hammond Milton L; Rohrer Susan P
6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.
Bioorganic & medicinal chemistry letters 2006;16(6):1468-72.
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2006: Lipfert Lorraine; Fisher John E; Wei Nan; Scafonas Angela; Su Qin; Yudkovitz Joel; Chen Fang; Warrier Sudha; Birzin Elizabeth T; Kim Seongkon; Chen Helen Y; Tan Qiang; Schmidt Azriel; Dininno Frank; Rohrer Susan P; Hammond Milton L; Rodan Gideon A; Freedman Leonard P; Reszka Alfred A
Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation.
Molecular endocrinology (Baltimore, Md.) 2006;20(3):516-33.
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2006: Blizzard Timothy A; Gude Candido; Morgan Jerry D; Chan Wanda; Birzin Elizabeth T; Mojena Marina; Tudela Consuelo; Chen Fang; Knecht Kristin; Su Qin; Kraker Bryan; Mosley Ralph T; Holmes Mark A; Sharma Nandini; Fitzgerald Paula M D; Rohrer Susan P; Hammond Milton L
Androstenediol analogs as ER-beta-selective SERMs.
Bioorganic & medicinal chemistry letters 2006;16(4):834-8.
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2005: Blizzard Timothy A; Morgan Jerry D; Chan Wanda; Birzin Elizabeth T; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; Mosley Ralph T; Yang Yi Tien; Rohrer Susan P; Dininno Frank; Hammond Milton L
Estrogen receptor ligands. Part 14: application of novel antagonist side chains to existing platforms.
Bioorganic & medicinal chemistry letters 2005;15(23):5124-8.
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2005: Chen Fang; Knecht Kristin; Birzin Elizabeth; Fisher John; Wilkinson Hilary; Mojena Marina; Moreno Consuelo Tudela; Schmidt Azriel; Harada Shun-ichi; Freedman Leonard P; Reszka Alfred A
Direct agonist/antagonist functions of dehydroepiandrosterone.
Endocrinology 2005;146(11):4568-76.
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2005: Blizzard Timothy A; DiNinno Frank; Chen Helen Y; Kim Seongkon; Wu Jane Y; Chan Wanda; Birzin Elizabeth T; Yang Yi Tien; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 13: Dihydrobenzoxathiin SERAMs with an optimized antagonist side chain.
Bioorganic & medicinal chemistry letters 2005;15(17):3912-6.
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2005: Neelamkavil Santhosh; Arison Byron; Birzin Elizabeth; Feng Jin-Jye; Chen Kuo-Hsin; Lin Atsui; Cheng Fong-Chi; Taylor Laurie; Thornton Edward R; Smith Amos B; Hirschmann Ralph
Replacement of Phe6, Phe7, and Phe11 of D-Trp8-somatostatin-14 with L-pyrazinylalanine. Predicted and observed effects on binding affinities at hSST2 and hSST4. An unexpected effect of the chirality of Trp8 on NMR spectra in methanol.
Journal of medicinal chemistry 2005;48(12):4025-30.
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2005: Angeles Angie R; Neagu Irina; Birzin Elizabeth T; Thornton Edward R; Smith Amos B; Hirschmann Ralph
Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1.
Organic letters 2005;7(6):1121-4.
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2005: Tan Qiang; Blizzard Timothy A; Morgan Jerry D; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; Warrier Sudha; Yudkovitz Joel; Wilkinson Hilary A; Sharma Nandini; Fitzgerald Paula M D; Li Susan; Colwell Lawrence; Fisher John E; Adamski Sharon; Reszka Alfred A; Kimmel Donald; DiNinno Frank; Rohrer Susan P; Freedman Leonard P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs.
Bioorganic & medicinal chemistry letters 2005;15(6):1675-81.
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2005: Liu Jian; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Pai Lee-Yuh; Dasilva Carolyn; Hayes Edward C; Mosley Ralph T; Dininno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 11: Synthesis and activity of isochromans and isothiochromans.
Bioorganic & medicinal chemistry letters 2005;15(3):715-8.
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2005: Blizzard Timothy A; Dininno Frank; Morgan Jerry D; Chen Helen Y; Wu Jane Y; Kim Seongkon; Chan Wanda; Birzin Elizabeth T; Yang Yi Tien; Pai Lee-Yuh; Fitzgerald Paula M D; Sharma Nandini; Li Ying; Zhang Zhoupeng; Hayes Edward C; Dasilva Carolyn A; Tang Wei; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorganic & medicinal chemistry letters 2005;15(1):107-13.
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2004: Blizzard Timothy A; DiNinno Frank; Morgan Jerry D; Wu Jane Y; Chen Helen Y; Kim Seongkon; Chan Wanda; Birzin Elizabeth T; Yang Yi Tien; Pai Lee-Yuh; Zhang Zhoupeng; Hayes Edward C; DaSilva Carolyn A; Tang Wei; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 8: Dihydrobenzoxathiin SERAMs with heteroatom-substituted side chains.
Bioorganic & medicinal chemistry letters 2004;14(15):3865-8.
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2004: Blizzard Timothy A; DiNinno Frank; Morgan Jerry D; Chen Helen Y; Wu Jane Y; Gude Candido; Kim Seongkon; Chan Wanda; Birzin Elizabeth T; Tien Yang Yi; Pai Lee-Yuh; Zhang Zhoupeng; Hayes Edward C; DaSilva Carolyn A; Tang Wei; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 7: Dihydrobenzoxathiin SERAMs with bicyclic amine side chains.
Bioorganic & medicinal chemistry letters 2004;14(15):3861-4.
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2004: Tan Qiang; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 6: Synthesis and binding affinity of dihydrobenzodithiins.
Bioorganic & medicinal chemistry letters 2004;14(14):3753-5.
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2004: Tan Qiang; Birzin Elizabeth T; Chan Wanda; Tien Yang Yi; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 5: The SAR of dihydrobenzoxathiins containing modified basic side chains.
Bioorganic & medicinal chemistry letters 2004;14(14):3747-51.
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2004: Kim Seongkon; Wu Jane; Chen Helen Y; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Colwell Lawrence; Li Susan; Dahllund Johanna; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs.
Bioorganic & medicinal chemistry letters 2004;14(11):2741-5.
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2004: Chen Helen Y; Kim Seongkon; Wu Jane Y; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Dahllund Johanna; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 3: The SAR of dihydrobenzoxathiin SERMs.
Bioorganic & medicinal chemistry letters 2004;14(10):2551-4.
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2004: Kim Seongkon; Wu Jane Y; Birzin Elizabeth T; Frisch Katalin; Chan Wanda; Pai Lee-Yuh; Yang Yi Tien; Mosley Ralph T; Fitzgerald Paula M D; Sharma Nandini; Dahllund Johanna; Thorsell Ann-Gerd; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators.
Journal of medicinal chemistry 2004;47(9):2171-5.
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2004: Chen Helen Y; Dykstra Kevin D; Birzin Elizabeth T; Frisch Katalin; Chan Wanda; Yang Yi T; Mosley Ralph T; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity.
Bioorganic & medicinal chemistry letters 2004;14(6):1417-21.
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2004: Blizzard Timothy A; Mosley Ralph T; Birzin Elizabeth T; Chan Wanda; Hammond Milton L
Comparison of 2-phenylspiroindenes and 2-phenylspiroindenediones as estrogen receptor ligands--modeling and binding data don't agree!
Bioorganic & medicinal chemistry letters 2004;14(5):1317-21.
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2003: Peekhaus Norbert T; Ferrer Marc; Chang Tina; Kornienko Oleg; Schneeweis Jonathan E; Smith Todd S; Hoffman Ira; Mitnaul Lyndon J; Chin Jayne; Fischer Paul A; Blizzard Tim A; Birzin Elizabeth T; Chan Wanda; Inglese James; Strulovici Berta; Rohrer Susan P; Schaeffer James M
A beta-lactamase-dependent Gal4-estrogen receptor beta transactivation assay for the ultra-high throughput screening of estrogen receptor beta agonists in a 3456-well format.
Assay and drug development technologies 2003;1(6):789-800.
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2003: Prasad Vidya; Birzin Elizabeth T; McVaugh Cheryl T; Van Rijn Rachel D; Rohrer Susan P; Chicchi Gary; Underwood Dennis J; Thornton Edward R; Smith Amos B; Hirschmann Ralph
Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents.
Journal of medicinal chemistry 2003;46(10):1858-69.
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2003: Blizzard Timothy A; Morgan Jerry D; Mosley Ralph T; Birzin Elizabeth T; Frisch Katalin; Rohrer Susan P; Hammond Milton L
2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs).
Bioorganic & medicinal chemistry letters 2003;13(3):479-83.
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2002: Birzin Elizabeth T; Rohrer Susan P
High-throughput receptor-binding methods for somatostatin receptor 2.
Analytical biochemistry 2002;307(1):159-66.
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2001: Zhou C; Guo L; Morriello G; Pasternak A; Pan Y; Rohrer S P; Birzin E T; Huskey S E; Jacks T; Schleim K D; Cheng K; Schaeffer J M; Patchett A A; Yang L
Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists.
Bioorganic & medicinal chemistry letters 2001;11(3):415-7.
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2000: Ye Z; Gao Y; Bakshi R K; Chen M H; Rohrer S P; Feighner S D; Pong S S; Howard A D; Blake A; Birzin E T; Locco L; Parmar R M; Chan W W; Schaeffer J M; Smith R G; Patchett A A; Nargund R P
Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.
Bioorganic & medicinal chemistry letters 2000;10(1):5-8.
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1999: Berk S C; Rohrer S P; Degrado S J; Birzin E T; Mosley R T; Hutchins S M; Pasternak A; Schaeffer J M; Underwood D J; Chapman K T
A combinatorial approach toward the discovery of non-peptide, subtype-selective somatostatin receptor ligands.
Journal of combinatorial chemistry 1999;1(5):388-96.
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1999: Pasternak A; Pan Y; Marino D; Sanderson P E; Mosley R; Rohrer S P; Birzin E T; Huskey S E; Jacks T; Schleim K D; Cheng K; Schaeffer J M; Patchett A A; Yang L
Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization.
Bioorganic & medicinal chemistry letters 1999;9(3):491-6.
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1998: Rohrer S P; Birzin E T; Mosley R T; Berk S C; Hutchins S M; Shen D M; Xiong Y; Hayes E C; Parmar R M; Foor F; Mitra S W; Degrado S J; Shu M; Klopp J M; Cai S J; Blake A; Chan W W; Pasternak A; Yang L; Patchett A A; Smith R G; Chapman K T; Schaeffer J M
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.
Science (New York, N.Y.) 1998;282(5389):737-40.
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1998: Yang L; Berk S C; Rohrer S P; Mosley R T; Guo L; Underwood D J; Arison B H; Birzin E T; Hayes E C; Mitra S W; Parmar R M; Cheng K; Wu T J; Butler B S; Foor F; Pasternak A; Pan Y; Silva M; Freidinger R M; Smith R G; Chapman K; Schaeffer J M; Patchett A A
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10836-41.
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1998: Yang L; Guo L; Pasternak A; Mosley R; Rohrer S; Birzin E; Foor F; Cheng K; Schaeffer J; Patchett A A
Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists.
Journal of medicinal chemistry 1998;41(13):2175-9.
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1996: Tsipouras A; Adefarati A A; Tkacz J S; Frazier E G; Rohrer S P; Birzin E; Rosegay A; Zink D L; Goetz M A; Singh S B; Schaeffer J M
Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity.
Bioorganic & medicinal chemistry 1996;4(4):531-6.
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1995: Rohrer S P; Birzin E T; Costa S D; Arena J P; Hayes E C; Schaeffer J M
Identification of neuron-specific ivermectin binding sites in Drosophila melanogaster and Schistocerca americana.
Insect biochemistry and molecular biology 1995;25(1):11-7.
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1994: Rohrer S P; Jacobson E B; Hayes E C; Birzin E T; Schaeffer J M
Immunoaffinity purification of avermectin-binding proteins from the free-living nematode Caenorhabditis elegans and the fruitfly Drosophila melanogaster.
The Biochemical journal 1994;302 ( Pt 2)():339-45.
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1994: Rohrer S P; Birzin E T; Eary C H; Schaeffer J M; Shoop W L
Ivermectin binding sites in sensitive and resistant Haemonchus contortus.
The Journal of parasitology 1994;80(3):493-7.
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