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Gino Salituro

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Christopher Sinz; Deborah Szalkowski; James R Tata; Laurie M Tota; Stella Vincent; Michael Wright; Shiyao Xu; Xiaodong Yang; Bei Zhang; Amy Bittner; Edward J Brady; Mari Candelore; Qing Dallas-Yang; Victor D H Ding; Guoqiang Jiang; Ronald Kim; Zhen Lin; Sajjad Qureshi; Gino M Salituro; Richard Saperstein; Jackie Shang; Emma R Parmee
Discovery of N-aryl-2-acylindole human glucagon receptor antagonists.
Christopher Sinz; Deborah Szalkowski; James R Tata; Laurie M Tota; Stella Vincent; Michael Wright; Shiyao Xu; Xiaodong Yang; Bei Zhang; Edward J Brady; Mari Candelore; Jiang Chang; Qing Dallas-Yang; Victor D H Ding; Guoqiang Jiang; Ronald Kim; Zhen Lin; Ashley Rouse Lins; Steve Mock; Sajjad Qureshi; Gino M Salituro; Richard Saperstein; Jackie Shang; Emma Parmee
Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists.
Shawn P Walsh; Alexandra Severino; Changyou Zhou; Jiafang He; Gui-Bai Liang; Carina P Tan; Jin Cao; George J Eiermann; Ling Xu; Gino M Salituro; Andrew D Howard; Sander G Mills; Lihu Yang
3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists.

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All Publications

2011: Christopher Sinz; Deborah Szalkowski; James R Tata; Laurie M Tota; Stella Vincent; Michael Wright; Shiyao Xu; Xiaodong Yang; Bei Zhang; Amy Bittner; Edward J Brady; Mari Candelore; Qing Dallas-Yang; Victor D H Ding; Guoqiang Jiang; Ronald Kim; Zhen Lin; Sajjad Qureshi; Gino M Salituro; Richard Saperstein; Jackie Shang; Emma R Parmee
Discovery of N-aryl-2-acylindole human glucagon receptor antagonists.
Bioorganic & medicinal chemistry letters 2011;21(23):7124-30.
2011: Christopher Sinz; Deborah Szalkowski; James R Tata; Laurie M Tota; Stella Vincent; Michael Wright; Shiyao Xu; Xiaodong Yang; Bei Zhang; Edward J Brady; Mari Candelore; Jiang Chang; Qing Dallas-Yang; Victor D H Ding; Guoqiang Jiang; Ronald Kim; Zhen Lin; Ashley Rouse Lins; Steve Mock; Sajjad Qureshi; Gino M Salituro; Richard Saperstein; Jackie Shang; Emma Parmee
Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists.
Bioorganic & medicinal chemistry letters 2011;21(23):7131-6.
2011: Shawn P Walsh; Alexandra Severino; Changyou Zhou; Jiafang He; Gui-Bai Liang; Carina P Tan; Jin Cao; George J Eiermann; Ling Xu; Gino M Salituro; Andrew D Howard; Sander G Mills; Lihu Yang
3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists.
Bioorganic & medicinal chemistry letters 2011;21(11):3390-4.
2011: Gregori J Morriello; Harvey R Wendt; Alka Bansal; Jerry Di Salvo; Scott Feighner; Jiafang He; Amanda L Hurley; Donna L Hreniuk; Gino M Salituro; Marat Vijay Reddy; Sheila M Galloway; Katherine K McGettigan; George Laws; Crystal McKnight; George A Doss; Nancy N Tsou; Regina M Black; Judy Morris; Richard G Ball; Anthony T Sanfiz; Eric Streckfuss; Mary Struthers; Scott D Edmondson
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonists.
Bioorganic & medicinal chemistry letters 2011;21(6):1865-70.
2010: Stephen D Goble; Liping Wang; K Lulu Howell; Alka Bansal; Richard Berger; Linda L Brockunier; Jerry DiSalvo; Scott Feighner; Bart Harper; Jiafang He; Amanda Hurley; Donna L Hreniuk; Emma Parmee; Michael Robbins; Gino M Salituro; Anthony Sanfiz; Eric Streckfuss; Eloisa Watkins; Ann E Weber; Mary Struthers; Scott D Edmondson
Heterocyclic acetamide and benzamide derivatives as potent and selective beta3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles.
Bioorganic & medicinal chemistry letters 2010;20(6):1895-9.
2010: Changyou Zhou; Cheng Tang; Eric Chang; Min Ge; Songnian Lin; Eric Cline; Carina P Tan; Yue Feng; Yun-Ping Zhou; George J Eiermann; Aleksandr Petrov; Gino M Salituro; Peter Meinke; Ralph T Mosley; Taro E Akiyama; Monica Einstein; Sanjeev Kumar; Joel P Berger; Andrew D Howard; Nancy A Thornberry; Sander G Mills; Lihu Yang
Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists.
Bioorganic & medicinal chemistry letters 2010;20(3):1298-301.
2009: H He; Kathryn A Lyons; Xiaolan Shen; Z Yao; K Bleasby; G Chan; M Hafey; X Li; Shiyao Xu; Gino M Salituro; L H Cohen; Wei Tang
Utility of unbound plasma drug levels and P-glycoprotein transport data in prediction of central nervous system exposure.
Xenobiotica; the fate of foreign compounds in biological systems 2009;39(9):687-93.
2002: Cameron J Smith; Nancy R Morin; Gerald F Bills; Anne W Dombrowski; Gino M Salituro; Scott K Smith; Annie Zhao; Douglas J MacNeil
Novel sesquiterpenoids from the fermentation of Xylaria persicaria are selective ligands for the NPY Y5 receptor.
The Journal of organic chemistry 2002;67(14):5001-4.
2002: Ellen L Air; Mathias Z Strowski; Stephen C Benoit; Stacey L Conarello; Gino M Salituro; Xiao-Ming Guan; Kun Liu; Stephen C Woods; Bei B Zhang
Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity.
Nature medicine 2002;8(2):179-83.
2001: Sheo B Singh; Hiranthi Jayasuriya; Gino M Salituro; Deborah L Zink; A Shafiee; B Heimbuch; Keith C Silverman; Russell Lingham; Olga Genilloud; Ana Teran; D Vilella; Peter J Felock; Daria J Hazuda
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I.
Journal of natural products 2001;64(7):874-82.
2001: Gino M Salituro; F Pelaez; Bei B Zhang
Discovery of a small molecule insulin receptor activator.
Recent progress in hormone research 2001;56():107-26.
2000: Michael A Weber; Anne Lidor; Subodh Arora; Gino M Salituro; B B Zhang; Anton N Sidawy
A novel insulin mimetic without a proliferative effect on vascular smooth muscle cells.
Journal of vascular surgery 2000;32(6):1118-26.
2000: Sajjad A Qureshi; Victor D H Ding; Zhihua Li; Deborah Szalkowski; Dawn E Biazzo-Ashnault; Dan Xie; Richard Saperstein; Edward J Brady; Su-Er W Huskey; Xiaolan Shen; Kun Liu; Libo Xu; Gino M Salituro; James V Heck; David E Moller; A Brian Jones; Bei B Zhang
Activation of insulin signal transduction pathway and anti-diabetic activity of small molecule insulin receptor activators.
The Journal of biological chemistry 2000;275(47):36590-5.
2000: Harold B Wood; R Black; Gino M Salituro; Deborah Szalkowski; Zhihua Li; Y Zhang; David E Moller; B Zhang; A Brian Jones
The basal SAR of a novel insulin receptor activator.
Bioorganic & medicinal chemistry letters 2000;10(11):1189-92.
1999: B Zhang; Gino M Salituro; Deborah Szalkowski; Zhihua Li; Y Zhang; Inmaculada Royo; D Vilella; M T Díez; Fernando Pelaez; Carolyn Ruby; R L Kendall; X Mao; P Griffin; JR Calaycay; J R Zierath; James V Heck; Roy G Smith; David E Moller
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice.
Science (New York, N.Y.) 1999;284(5416):974-7.