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Konstantin Salnikow

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Kazimierz S Kasprzak; Daniel L Logsdon; Bhalchandra A Diwan; Mathew J Fivash; Monika Z Kaczmarek; Konstantin Salnikow
Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice.
Monika Kaczmarek; Raul E Cachau; Igor A Topol; Kazimierz S Kasprzak; Andy Ghio; Konstantin Salnikow
Metal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha protein.
Konstantin Salnikow; Olga Aprelikova; Sergey Ivanov; Sean Tackett; Monika Kaczmarek; Aldona A Karaczyn; Herman Yee; Kazimierz S Kasprzak; John E Niederhuber
Regulation of hypoxia-inducible genes by ETS1 transcription factor.

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All Publications

2011: Kazimierz S Kasprzak; Daniel L Logsdon; Bhalchandra A Diwan; Mathew J Fivash; Monika Z Kaczmarek; Konstantin Salnikow
Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice.
Toxicology and applied pharmacology 2011;257(1):32-7.
2009: Monika Kaczmarek; Raul E Cachau; Igor A Topol; Kazimierz S Kasprzak; Andy Ghio; Konstantin Salnikow
Metal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha protein.
Toxicological sciences : an official journal of the Society of Toxicology 2009;107(2):394-403.
2008: Konstantin Salnikow; Olga Aprelikova; Sergey Ivanov; Sean Tackett; Monika Kaczmarek; Aldona A Karaczyn; Herman Yee; Kazimierz S Kasprzak; John E Niederhuber
Regulation of hypoxia-inducible genes by ETS1 transcription factor.
Carcinogenesis 2008;29(8):1493-9.
2008: Sergey V Ivanov; Alla V Ivanova; Konstantin Salnikow; Olga Timofeeva; Malayannan Subramaniam; Michael I Lerman
Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors.
Biochemical and biophysical research communications 2008;370(4):536-40.
2008: Arkadiusz Surazynski; Steven P Donald; Sandra K Cooper; Martin A Whiteside; Konstantin Salnikow; Yongmin Liu; James M Phang
Extracellular matrix and HIF-1 signaling: the role of prolidase.
International journal of cancer. Journal international du cancer 2008;122(6):1435-40.
2008: Konstantin Salnikow; Anatoly Zhitkovich
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium.
Chemical research in toxicology 2008;21(1):28-44.
2007: S P Doherty; Colette Prophete; Polina Maciejczyk; Konstantin Salnikow; Timothy Gould; Timothy Larson; Jane Koenig; P Jaques; Constantinos Sioutas; Judith T Zelikoff; Morton Lippmann; Mitchell D Cohen
Detection of changes in alveolar macrophage iron status induced by select PM2.5-associated components using iron-response protein binding activity.
Inhalation toxicology 2007;19(6-7):553-62.
2007: Monika Kaczmarek; Olga Timofeeva; Aldona A Karaczyn; Anatoli Malyguine; Kazimierz S Kasprzak; Konstantin Salnikow
The role of ascorbate in the modulation of HIF-1alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II).
Free radical biology & medicine 2007;42(8):1246-57.
2006: Colette Prophete; Polina Maciejczyk; Konstantin Salnikow; Timothy Gould; Timothy Larson; Jane Koenig; Peter Jaques; Constantinos Sioutas; Morton Lippmann; Mitchell Cohen
Effects of select PM-associated metals on alveolar macrophage phosphorylated ERK1 and -2 and iNOS expression during ongoing alteration in iron homeostasis.
Journal of toxicology and environmental health. Part A 2006;69(10):935-51.
2006: Aldona A Karaczyn; Sergey Ivanov; Mindy Reynolds; Anatoly Zhitkovich; Kazimierz S Kasprzak; Konstantin Salnikow
Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel.
Journal of cellular biochemistry 2006;97(5):1025-35.
2006: Igor A Topol; Alexander V Nemukhin; Konstantin Salnikow; Raul E Cachau; Yuri G Abashkin; Kazimierz S Kasprzak; Stanley K Burt
Quantum chemical modeling of reaction mechanism for 2-oxoglutarate dependent enzymes: effect of substitution of iron by nickel and cobalt.
The journal of physical chemistry. A 2006;110(12):4223-8.
2005: Renata Kowara; Aldona A Karaczyn; Robert Y S Cheng; Konstantin Salnikow; Kazimierz S Kasprzak
Microarray analysis of altered gene expression in murine fibroblasts transformed by nickel(II) to nickel(II)-resistant malignant phenotype.
Toxicology and applied pharmacology 2005;205(1):1-10.
2005: Konstantin Salnikow; Kazimierz S Kasprzak
Ascorbate depletion: a critical step in nickel carcinogenesis?
Environmental health perspectives 2005;113(5):577-84.
2005: David Zagzag; Konstantin Salnikow; Luis Chiriboga; Herman Yee; Li Lan; Mehboob Ali; Roberto Garcia; Sandra Demaria; Elizabeth W Newcomb
Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain.
Laboratory investigation; a journal of technical methods and pathology 2005;85(3):328-41.
2004: Konstantin Salnikow; Steven P Donald; Richard K Bruick; Anatoly Zhitkovich; James M Phang; Kazimierz S Kasprzak
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
The Journal of biological chemistry 2004;279(39):40337-44.
2004: Konstantin Salnikow; Xiaomei Li; Morton Lippmann
Effect of nickel and iron co-exposure on human lung cells.
Toxicology and applied pharmacology 2004;196(2):258-65.
2004: Renata Kowara; Konstantin Salnikow; Bhalchandra A Diwan; Robert M Bare; Michael P Waalkes; Kazimierz S Kasprzak
Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas.
Molecular and cellular biochemistry 2004;255(1-2):195-202.
2004: Robert P Caruso; Benjamin Levinson; Jonathan Melamed; Rosemary Wieczorek; Samir Taneja; David Polsky; Caroline Chang; Anne Zeleniuch-Jacquotte; Konstantin Salnikow; Herman Yee; Max Costa; Iman Osman
Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):222-7.
2004: Jianhua Zhao; Yan Yan; Konstantin Salnikow; Thomas Kluz; Max Costa
Nickel-induced down-regulation of serpin by hypoxic signaling.
Toxicology and applied pharmacology 2004;194(1):60-8.
2004: Patrick Maxwell; Konstantin Salnikow
HIF-1: an oxygen and metal responsive transcription factor.
Cancer biology & therapy 2004;3(1):29-35.
2003: Kazimierz S Kasprzak; F William Sunderman; Konstantin Salnikow
Nickel carcinogenesis.
Mutation research 2003;533(1-2):67-97.
2003: Todd Davidson; Konstantin Salnikow; Max Costa
Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel.
Molecular pharmacology 2003;64(6):1485-93.
2003: Qunwei Zhang; Konstantin Salnikow; Thomas Kluz; Lung Chi Chen; WC Su; Max Costa
Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A.
Toxicology and applied pharmacology 2003;192(3):201-11.
2003: Konstantin Salnikow; Todd Davidson; Qunwei Zhang; Lung Chi Chen; WC Su; Max Costa
The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.
Cancer research 2003;63(13):3524-30.
2003: Max Costa; Yan Yan; Daoji Zhao; Konstantin Salnikow
Molecular mechanisms of nickel carcinogenesis: gene silencing by nickel delivery to the nucleus and gene activation/inactivation by nickel-induced cell signaling.
Journal of environmental monitoring : JEM 2003;5(2):222-3.
2003: Konstantin Salnikow; Todd Davidson; Thomas Kluz; Haobin Chen; Daoji Zhou; Max Costa
GeneChip analysis of signaling pathways effected by nickel.
Journal of environmental monitoring : JEM 2003;5(2):206-9.
2003: Ivan Ding; Paul Okunieff; Konstantin Salnikow; Weimin Liu; Bruce Fenton
A new intrinsic hypoxia marker in esophageal cancer.
Advances in experimental medicine and biology 2003;540():227-33.
2002: Hakan Cangul; Konstantin Salnikow; Herman Yee; David Zagzag; Thérèse Commes; Max Costa
Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.
Environmental health perspectives 2002;110 Suppl 5():783-8.
2002: Konstantin Salnikow; Todd Davidson; Max Costa
The role of hypoxia-inducible signaling pathway in nickel carcinogenesis.
Environmental health perspectives 2002;110 Suppl 5():831-4.
2002: Maria Antonietta Zoroddu; Laura Schinocca; Teresa Kowalik-Jankowska; Henryk Kozlowski; Konstantin Salnikow; Max Costa
Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4.
Environmental health perspectives 2002;110 Suppl 5():719-23.
2002: Max Costa; Konstantin Salnikow; Jessica E Sutherland; Limor Broday; Wu Peng; Qunwei Zhang; Thomas Kluz
The role of oxidative stress in nickel and chromate genotoxicity.
Molecular and cellular biochemistry 2002;234-235(1-2):265-75.
2002: Qunwei Zhang; Thomas Kluz; Konstantin Salnikow; Max Costa
Comparison of the cytotoxicity, cellular uptake, and DNA-protein crosslinks induced by potassium chromate in lymphoblast cell lines derived from three different individuals.
Biological trace element research 2002;86(1):11-22.
2002: Konstantin Salnikow; Thomas Kluz; Max Costa; David Piquemal; Zoya N Demidenko; Keping Xie; Mikhail V Blagosklonny
The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia.
Molecular and cellular biology 2002;22(6):1734-41.
2002: Hakan Cangul; Limor Broday; Konstantin Salnikow; J Sutherland; Wu Peng; Qunwei Zhang; V Poltaratsky; Herman Yee; Maria Antonietta Zoroddu; Max Costa
Molecular mechanisms of nickel carcinogenesis.
Toxicology letters 2002;127(1-3):69-75.
2002: Konstantin Salnikow; Mitchell D Cohen
Backing into cancer: effects of arsenic on cell differentiation.
Toxicological sciences : an official journal of the Society of Toxicology 2002;65(2):161-3.
2002: Hakan Cangul; Konstantin Salnikow; Herman Yee; David Zagzag; Thérèse Commes; Max Costa
Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis.
Cell biology and toxicology 2002;18(2):87-96.
2001: Max Costa; Jessica E Sutherland; Wu Peng; Konstantin Salnikow; Limor Broday; Thomas Kluz
Molecular biology of nickel carcinogenesis.
Molecular and cellular biochemistry 2001;222(1-2):205-11.
2001: Maria Antonietta Zoroddu; Teresa Kowalik-Jankowska; Henryk Kozlowski; Konstantin Salnikow; Max Costa
Ni(II) and Cu(II) binding with a 14-aminoacid sequence of Cap43 protein, TRSRSHTSEGTRSR.
Journal of inorganic biochemistry 2001;84(1-2):47-54.
2001: J Azare; Irene Pankova-Kholmyansky; Konstantin Salnikow; D Cohen; Eliezer Flescher
Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein.
Oncology research 2001;12(8):315-23.
2000: Konstantin Salnikow; Max Costa; W D Figg; Mikhail V Blagosklonny
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.
Cancer research 2000;60(20):5630-4.
2000: Maria Antonietta Zoroddu; Teresa Kowalik-Jankowska; Henryk Kozlowski; H Molinari; Konstantin Salnikow; Limor Broday; Max Costa
Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail.
Biochimica et biophysica acta 2000;1475(2):163-8.
2000: Konstantin Salnikow; WC Su; Mikhail V Blagosklonny; Max Costa
Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism.
Cancer research 2000;60(13):3375-8.
2000: Limor Broday; Wu Peng; M H Kuo; Konstantin Salnikow; Maria Antonietta Zoroddu; Max Costa
Nickel compounds are novel inhibitors of histone H4 acetylation.
Cancer research 2000;60(2):238-41.
2000: Konstantin Salnikow; Max Costa
Epigenetic mechanisms of nickel carcinogenesis.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2000;19(3):307-18.
2000: Konstantin Salnikow; Mikhail V Blagosklonny; H Ryan; R Johnson; Max Costa
Carcinogenic nickel induces genes involved with hypoxic stress.
Cancer research 2000;60(1):38-41.
1999: Konstantin Salnikow; Thomas Kluz; Max Costa
Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression.
Toxicology and applied pharmacology 1999;160(2):127-32.
1999: Konstantin Salnikow; Won G An; Giovanni Melillo; Mikhail V Blagosklonny; Max Costa
Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors.
Carcinogenesis 1999;20(9):1819-23.
1998: D Zhou; Konstantin Salnikow; Max Costa
Cap43, a novel gene specifically induced by Ni2+ compounds.
Cancer research 1998;58(10):2182-9.
1998: Eliezer Flescher; H Tripoli; Konstantin Salnikow; F J Burns
Oxidative stress suppresses transcription factor activities in stimulated lymphocytes.
Clinical and experimental immunology 1998;112(2):242-7.
1997: Konstantin Salnikow; S Wang; Max Costa
Induction of activating transcription factor 1 by nickel and its role as a negative regulator of thrombospondin I gene expression.
Cancer research 1997;57(22):5060-6.
1997: Valery Krasnoperov; Mary A Bittner; Ronald C Beavis; Y Kuang; Konstantin Salnikow; Oleg G Chepurny; Roger Little; A N Plotnikov; D Wu; Ronald W Holz; Alexander G Petrenko
alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor.
Neuron 1997;18(6):925-37.
1995: Y W Lee; Catherine B Klein; B Kargacin; Konstantin Salnikow; J Kitahara; K Dowjat; Anatoly Zhitkovich; N T Christie; Max Costa
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens.
Molecular and cellular biology 1995;15(5):2547-57.
1994: Konstantin Salnikow; M Gao; V Voitkun; X Huang; Max Costa
Altered oxidative stress responses in nickel-resistant mammalian cells.
Cancer research 1994;54(24):6407-12.
1994: Max Costa; Konstantin Salnikow; S Cosentino; Catherine B Klein; X Huang; Z Zhuang
Molecular mechanisms of nickel carcinogenesis.
Environmental health perspectives 1994;102 Suppl 3():127-30.
1994: Max Costa; Z Zhuang; X Huang; S Cosentino; Catherine B Klein; Konstantin Salnikow
Molecular mechanisms of nickel carcinogenesis.
The Science of the total environment 1994;148(2-3):191-9.
1994: Konstantin Salnikow; S Cosentino; C Klein; Max Costa
Loss of thrombospondin transcriptional activity in nickel-transformed cells.
Molecular and cellular biology 1994;14(1):851-8.
1992: Konstantin Salnikow; Anatoly Zhitkovich; Max Costa
Analysis of the binding sites of chromium to DNA and protein in vitro and in intact cells.
Carcinogenesis 1992;13(12):2341-6.