Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Severo Salvadori

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Concepts & Ideas

Living Beings

Genes & Molecular Sequences

Amino Acid Sequence

Anatomy

Physiology

Competitive Binding

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Mabrouk O S; Marti M; Salvadori S; Morari M
The novel delta opioid receptor agonist UFP-512 dually modulates motor activity in hemiparkinsonian rats via control of the nigro-thalamic pathway.
Balboni Gianfranco; Trapella Claudio; Sasaki Yusuke; Ambo Akihiro; Marczak Ewa D; Lazarus Lawrence H; Salvadori Severo
Influence of the side chain next to C-terminal benzimidazole in opioid pseudopeptides containing the Dmt-Tic pharmacophore.
Giannini Elisa; Lattanzi Roberta; Nicotra Annalisa; Campese Antonio F; Grazioli Paola; Screpanti Isabella; Balboni Gianfranco; Salvadori Severo; Sacerdote Paola; Negri Lucia
The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Severo Salvadori (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Mabrouk O S; Marti M; Salvadori S; Morari M
The novel delta opioid receptor agonist UFP-512 dually modulates motor activity in hemiparkinsonian rats via control of the nigro-thalamic pathway.
Neuroscience 2009;164(2):360-9.
2009: Balboni Gianfranco; Trapella Claudio; Sasaki Yusuke; Ambo Akihiro; Marczak Ewa D; Lazarus Lawrence H; Salvadori Severo
Influence of the side chain next to C-terminal benzimidazole in opioid pseudopeptides containing the Dmt-Tic pharmacophore.
Journal of medicinal chemistry 2009;52(17):5556-9.
2009: Giannini Elisa; Lattanzi Roberta; Nicotra Annalisa; Campese Antonio F; Grazioli Paola; Screpanti Isabella; Balboni Gianfranco; Salvadori Severo; Sacerdote Paola; Negri Lucia
The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14646-51.
2009: Marczak Ewa D; Jinsmaa Yunden; Myers Page H; Blankenship Terry; Wilson Ralph; Balboni Gianfranco; Salvadori Severo; Lazarus Lawrence H
Orally administered H-Dmt-Tic-Lys-NH-CH2-Ph (MZ-2), a potent mu/delta-opioid receptor antagonist, regulates obese-related factors in mice.
European journal of pharmacology 2009;616(1-3):115-21.
2009: Trapella Claudio; Fischetti Carmela; Pela' Michela; Lazzari Ilaria; Guerrini Remo; Calo' Girolamo; Rizzi Anna; Camarda Valeria; Lambert David G; McDonald John; Regoli Domenico; Salvadori Severo
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide.
Bioorganic & medicinal chemistry 2009;17(14):5080-95.
2009: Guerrini Remo; Camarda Valeria; Trapella Claudio; Caló Girolamo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists.
Journal of medicinal chemistry 2009;52(13):4068-71.
2009: Fischetti Carmela; Camarda Valeria; Rizzi Anna; Pelà Michela; Trapella Claudio; Guerrini Remo; McDonald John; Lambert David G; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.
European journal of pharmacology 2009;614(1-3):50-7.
2009: Batuwangala Madura; Camarda Valeria; McDonald John; Marzola Erika; Lambert David G; Ng Leong L; Calo' Girolamo; Regoli Domenico; Trapella Claudio; Guerrini Remo; Salvadori Severo
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor.
Peptides 2009;30(6):1130-6.
2009: Camarda Valeria; Rizzi Anna; Ruzza Chiara; Zucchini Silvia; Marzola Giuliano; Marzola Erika; Guerrini Remo; Salvadori Severo; Reinscheid Rainer K; Regoli Domenico; Calò Girolamo
In vitro and in vivo pharmacological characterization of the neuropeptide s receptor antagonist [D-Cys(tBu)5]neuropeptide S.
The Journal of pharmacology and experimental therapeutics 2009;328(2):549-55.
2009: Guerrini Remo; Camarda Valeria; Trapella Claudio; Calò Girolamo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists.
Journal of medicinal chemistry 2009;52(2):524-9.
2009: Ballet Steven; Feytens Debby; Wachter Rien De; Vlaeminck Magali De; Marczak Ewa D; Salvadori Severo; Graaf Chris de; Rognan Didier; Negri Lucia; Lattanzi Roberta; Lazarus Lawrence H; Tourwé Dirk; Balboni Gianfranco
Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold.
Bioorganic & medicinal chemistry letters 2009;19(2):433-7.
2008: Balboni Gianfranco; Lazzari Ilaria; Trapella Claudio; Negri Lucia; Lattanzi Roberta; Giannini Elisa; Nicotra Annalisa; Melchiorri Pietro; Visentin Sergio; Nuccio Chiara De; Salvadori Severo
Triazine compounds as antagonists at Bv8-prokineticin receptors.
Journal of medicinal chemistry 2008;51(23):7635-9.
2008: Camarda Valeria; Trapella Claudio; Calo' Girolamo; Guerrini Remo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Structure-activity study at positions 3 and 4 of human neuropeptide S.
Bioorganic & medicinal chemistry 2008;16(19):8841-5.
2008: Jinsmaa Yunden; Marczak Ewa D; Balboni Gianfranco; Salvadori Severo; Lazarus Lawrence H
Inhibition of the development of morphine tolerance by a potent dual mu-delta-opioid antagonist, H-Dmt-Tic-Lys-NH-CH2-Ph.
Pharmacology, biochemistry, and behavior 2008;90(4):651-7.
2008: Savoia Dianella; Guerrini Remo; Marzola Erika; Salvadori Severo
Synthesis and antimicrobial activity of dermaseptin S1 analogues.
Bioorganic & medicinal chemistry 2008;16(17):8205-9.
2008: Chao Dongman; Bazzy-Asaad Alia; Balboni Gianfranco; Salvadori Severo; Xia Ying
Activation of DOR attenuates anoxic K+ derangement via inhibition of Na+ entry in mouse cortex.
Cerebral cortex (New York, N.Y. : 1991) 2008;18(9):2217-27.
2008: Balboni Gianfranco; Fiorini Stella; Baldisserotto Anna; Trapella Claudio; Sasaki Yusuke; Ambo Akihiro; Marczak Ewa D; Lazarus Lawrence H; Salvadori Severo
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic.
Journal of medicinal chemistry 2008;51(16):5109-17.
2008: Rizzi A; Vergura R; Marzola G; Ruzza C; Guerrini R; Salvadori S; Regoli D; Calo G
Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.
British journal of pharmacology 2008;154(2):471-9.
2008: Marzola Erika; Camarda Valeria; Batuwangala Madura; Lambert David G; Calo' Girolamo; Guerrini Remo; Trapella Claudio; Regoli Domenico; Tomatis Roberto; Salvadori Severo
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11).
Peptides 2008;29(5):674-9.
2008: Ryu Eun Kyoung; Wu Zhanhong; Chen Kai; Lazarus Lawrence H; Marczak Ewa D; Sasaki Yusuke; Ambo Akihiro; Salvadori Severo; Ren Chuancheng; Zhao Heng; Balboni Gianfranco; Chen Xiaoyuan
Synthesis of a potent and selective (18)F-labeled delta-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for positron emission tomography imaging.
Journal of medicinal chemistry 2008;51(6):1817-23.
2008: Salvadori Severo; Fiorini Stella; Trapella Claudio; Porreca Frank; Davis Peg; Sasaki Yusuke; Ambo Akihiro; Marczak Ewa D; Lazarus Lawrence H; Balboni Gianfranco
Role of benzimidazole (Bid) in the delta-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502).
Bioorganic & medicinal chemistry 2008;16(6):3032-8.
2008: Camarda Valeria; Trapella Claudio; Calo Girolamo; Guerrini Remo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Synthesis and biological activity of human neuropeptide S analogues modified in position 2.
Journal of medicinal chemistry 2008;51(3):655-8.
2008: Vergura Raffaella; Balboni Gianfranco; Spagnolo Barbara; Gavioli Elaine; Lambert David G; McDonald John; Trapella Claudio; Lazarus Lawrence H; Regoli Domenico; Guerrini Remo; Salvadori Severo; Caló Girolamo
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist.
Peptides 2008;29(1):93-103.
2007: Salvadori Severo; Trapella Claudio; Fiorini Stella; Negri Lucia; Lattanzi Roberta; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H; Balboni Gianfranco
A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-Tic.
Bioorganic & medicinal chemistry 2007;15(22):6876-81.
2007: Tancredi Teodorico; Guerrini Remo; Marzola Erika; Trapella Claudio; Calo Girolamo; Regoli Domenico; Reinscheid Rainer K; Camarda Valeria; Salvadori Severo; Temussi Piero Andrea
Conformation-activity relationship of neuropeptide S and some structural mutants: helicity affects their interaction with the receptor.
Journal of medicinal chemistry 2007;50(18):4501-8.
2007: Arduin Marika; Spagnolo Barbara; Calò Girolamo; Guerrini Remo; Carrà Giacomo; Fischetti Carmela; Trapella Claudio; Marzola Erika; McDonald John; Lambert David G; Regoli Domenico; Salvadori Severo
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Calpha,alpha-dialkylated amino acids.
Bioorganic & medicinal chemistry 2007;15(13):4434-43.
2007: Rizzi Anna; Spagnolo Barbara; Wainford Richard D; Fischetti Carmela; Guerrini Remo; Marzola Giuliano; Baldisserotto Anna; Salvadori Severo; Regoli Domenico; Kapusta Daniel R; Calo Girolamo
In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor.
Peptides 2007;28(6):1240-51.
2007: Pastore Annalisa; Salvadori Severo; Temussi Piero Andrea
Peptides and proteins in a confined environment: NMR spectra at natural isotopic abundance.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(5):342-7.
2007: Balboni Gianfranco; Onnis Valentina; Congiu Cenzo; Zotti Margherita; Sasaki Yusuke; Ambo Akihiro; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H; Lazzari Ilaria; Trapella Claudio; Salvadori Severo
Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore.
Bioorganic & medicinal chemistry 2007;15(9):3143-51.
2007: Nazzaro Cristiano; Rizzi Anna; Salvadori Severo; Guerrini Remo; Regoli Domenico; Zeilhofer Hanns Ulrich; Calo Girolamo
UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ: behavioral and electrophysiological studies in mice.
Peptides 2007;28(3):663-9.
2006: Vergura Raffaella; Valenti Elena; Hebbes Christopher P; Gavioli Elaine C; Spagnolo Barbara; McDonald John; Lambert David G; Balboni Gianfranco; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Dmt-Tic-NH-CH2-Bid (UFP-502), a potent DOP receptor agonist: in vitro and in vivo studies.
Peptides 2006;27(12):3322-30.
2006: Lazzeri Massimo; Calò Girolamo; Spinelli Michele; Malaguti Silvia; Guerrini Remo; Salvadori Severo; Beneforti Patrizia; Regoli Domenico; Turini Damiano
Daily intravesical instillation of 1 mg nociceptin/orphanin FQ for the control of neurogenic detrusor overactivity: a multicenter, placebo controlled, randomized exploratory study.
The Journal of urology 2006;176(5):2098-102.
2006: Neumeyer John L; Peng Xuemei; Knapp Brian I; Bidlack Jean M; Lazarus Lawrence H; Salvadori Severo; Trapella Claudio; Balboni Gianfranco
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores.
Journal of medicinal chemistry 2006;49(18):5640-3.
2006: Balboni Gianfranco; Onnis Valentina; Congiu Cenzo; Zotti Margherita; Sasaki Yusuke; Ambo Akihiro; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H; Trapella Claudio; Salvadori Severo
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore.
Journal of medicinal chemistry 2006;49(18):5610-7.
2006: Roth Adelheid L; Marzola Erika; Rizzi Anna; Arduin Marika; Trapella Claudio; Corti Corrado; Vergura Raffaella; Martinelli Prisca; Salvadori Severo; Regoli Domenico; Corsi Mauro; Cavanni Paolo; Caló Girolamo; Guerrini Remo
Structure-activity studies on neuropeptide S: identification of the amino acid residues crucial for receptor activation.
The Journal of biological chemistry 2006;281(30):20809-16.
2006: Ballet Steven; Salvadori Severo; Trapella Claudio; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H; Negri Lucia; Giannini Elisa; Lattanzi Roberta; Tourwé Dirk; Balboni Gianfranco
New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands.
Journal of medicinal chemistry 2006;49(13):3990-3.
2006: Vázquez M Eugenio; Blanco Juan B; Salvadori Severo; Trapella Claudio; Argazzi Roberto; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H; Negri Lucia; Giannini Elisa; Lattanzi Roberta; Colucci Mariantonella; Balboni Gianfranco
6-N,N-dimethylamino-2,3-naphthalimide: a new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides.
Journal of medicinal chemistry 2006;49(12):3653-8.
2006: Trapella Claudio; Guerrini Remo; Piccagli Laura; Calo' Girolamo; Carra' Giacomo; Spagnolo Barbara; Rubini Samantha; Fanton Giulia; Hebbes Christopher; McDonald John; Lambert David G; Regoli Domenico; Salvadori Severo
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.
Bioorganic & medicinal chemistry 2006;14(3):692-704.
2006: Camarda Valeria; Spagnol Martina; Song Wei; Vergura Raffaella; Roth Adelheid L; Thompson Jonathan P; Rowbotham David J; Guerrini Remo; Marzola Erika; Salvadori Severo; Cavanni Paolo; Regoli Domenico; Douglas Stephen A; Lambert David G; Calò Girolamo
In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5,DTrp7,Dab8]urotensin II(4-11) (UFP-803).
British journal of pharmacology 2006;147(1):92-100.
2005: Balboni Gianfranco; Guerrini Remo; Salvadori Severo; Negri Lucia; Giannini Elisa; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Conversion of the potent delta-opioid agonist H-Dmt-Tic-NH-CH(2)-bid into delta-opioid antagonists by N(1)-benzimidazole alkylation(1).
Journal of medicinal chemistry 2005;48(26):8112-4.
2005: Li Tingyou; Fujita Yoshio; Shiotani Kimitaka; Miyazaki Anna; Tsuda Yuko; Ambo Akihiro; Sasaki Yusuke; Jinsmaa Yunden; Marczak Ewa; Bryant Sharon D; Salvadori Severo; Lazarus Lawrence H; Okada Yoshio
Potent Dmt-Tic pharmacophoric delta- and mu-opioid receptor antagonists.
Journal of medicinal chemistry 2005;48(25):8035-44.
2005: Marti Matteo; Mela Flora; Fantin Martina; Zucchini Silvia; Brown Jeffrey M; Witta Jassir; Di Benedetto Manuela; Buzas Beata; Reinscheid Rainer K; Salvadori Severo; Guerrini Remo; Romualdi Patrizia; Candeletti Sanzio; Simonato Michele; Cox Brian M; Morari Michele
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(42):9591-601.
2005: Balboni Gianfranco; Cocco Maria Teresa; Salvadori Severo; Romagnoli Romeo; Sasaki Yusuke; Okada Yoshio; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
From the potent and selective mu opioid receptor agonist H-Dmt-d-Arg-Phe-Lys-NH(2) to the potent delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OH.
Journal of medicinal chemistry 2005;48(17):5608-11.
2005: Carra' G; Calo' G; Spagnolo B; Guerrini R; Arduin M; Marzola E; Trapella C; Regoli D; Salvadori S
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2.
The journal of peptide research : official journal of the American Peptide Society 2005;66(1):39-47.
2005: Marchetti Nicola; Dondi Francesco; Felinger Attila; Guerrini Remo; Salvadori Severo; Cavazzini Alberto
Modeling of overloaded gradient elution of nociceptin/orphanin FQ in reversed-phase liquid chromatography.
Journal of chromatography. A 2005;1079(1-2):162-72.
2005: Guerrini Remo; Caló Girolamo; Lambert David G; Carrá Giacomo; Arduin Marika; Barnes Tim A; McDonald John; Rizzi Daniela; Trapella Claudio; Marzola Erika; Rowbotham David J; Regoli Domenico; Salvadori Severo
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands.
Journal of medicinal chemistry 2005;48(5):1421-7.
2005: Tancredi Teodorico; Carrà Giacomo; Guerrini Remo; Arduin Marika; Calò Girolamo; Regoli Domenico; Salvadori Severo; Temussi Piero Andrea
The interaction of highly helical structural mutants with the NOP receptor discloses the role of the address domain of nociceptin/orphanin FQ.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(7):2061-70.
2005: Carrà Giacomo; Rizzi Anna; Guerrini Remo; Barnes Timothy A; McDonald John; Hebbes Christopher P; Mela Flora; Kenigs Velga A; Marzola Giuliano; Rizzi Daniela; Gavioli Elaine; Zucchini Silvia; Regoli Domenico; Morari Michele; Salvadori Severo; Rowbotham David J; Lambert David G; Kapusta Daniel R; Calo' Girolamo
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1114-23.
2005: Guerrini Remo; Camarda Valeria; Marzola Erika; Arduin Marika; Calo Girolamo; Spagnol Martina; Rizzi Anna; Salvadori Severo; Regoli Domenico
Structure-activity relationship study on human urotensin II.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(2):85-90.
2005: Calo Girolamo; Guerrini Remo; Rizzi Anna; Salvadori Severo; Burmeister Melissa; Kapusta Daniel R; Lambert David G; Regoli Domenico
UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor.
CNS drug reviews 2005;11(2):97-112.
2004: Balboni Gianfranco; Salvadori Severo; Dal Piaz Alessandro; Bortolotti Fabrizio; Argazzi Roberto; Negri Lucia; Lattanzi Roberta; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.
Journal of medicinal chemistry 2004;47(26):6541-6.
2004: Martin Stephen R; Biekofsky Rodolfo R; Skinner Murray A; Guerrini Remo; Salvadori Severo; Feeney James; Bayley Peter M
Interaction of calmodulin with the phosphofructokinase target sequence.
FEBS letters 2004;577(1-2):284-8.
2004: Vergura Raffaella; Camarda Valeria; Rizzi Anna; Spagnol Martina; Guerrini Remo; Calo' Girolamo; Salvadori Severo; Regoli Domenico
Urotensin II stimulates plasma extravasation in mice via UT receptor activation.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(5):347-52.
2004: Camarda Valeria; Song Wei; Marzola Erika; Spagnol Martina; Guerrini Remo; Salvadori Severo; Regoli Domenico; Thompson Jonathan P; Rowbotham David J; Behm David J; Douglas Stephen A; Calo' Girolamo; Lambert David G
Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors.
European journal of pharmacology 2004;498(1-3):83-6.
2004: D'Ursi Anna M; Armenante Maria R; Guerrini Remo; Salvadori Severo; Sorrentino Giuseppe; Picone Delia
Solution structure of amyloid beta-peptide (25-35) in different media.
Journal of medicinal chemistry 2004;47(17):4231-8.
2004: Marti Matteo; Mela Flora; Veronesi Carlo; Guerrini Remo; Salvadori Severo; Federici Mauro; Mercuri Nicola B; Rizzi Anna; Franchi Gianfranco; Beani Lorenzo; Bianchi Clementina; Morari Michele
Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(30):6659-66.
2004: Balboni Gianfranco; Salvadori Severo; Guerrini Remo; Negri Lucia; Giannini Elisa; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Direct influence of C-terminally substituted amino acids in the Dmt-Tic pharmacophore on delta-opioid receptor selectivity and antagonism.
Journal of medicinal chemistry 2004;47(16):4066-71.
2004: Gavioli E C; Vaughan C W; Marzola G; Guerrini R; Mitchell V A; Zucchini S; De Lima T C M; Rae G A; Salvadori S; Regoli D; Calo' G
Antidepressant-like effects of the nociceptin/orphanin FQ receptor antagonist UFP-101: new evidence from rats and mice.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(6):547-53.
2004: Guerrini R; Carra' G; Calo' G; Trapella C; Marzola E; Rizzi D; Regoli D; Salvadori S
Nonpeptide/peptide chimeric ligands for the nociceptin/orphanin FQ receptor: design, synthesis and in vitro pharmacological activity.
The journal of peptide research : official journal of the American Peptide Society 2004;63(6):477-84.
2004: Tancredi Teodorico; Pastore Annalisa; Salvadori Severo; Esposito Veronica; Temussi Piero A
Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin.
European journal of biochemistry / FEBS 2004;271(11):2231-40.
2004: Mela Flora; Marti Matteo; Ulazzi Linda; Vaccari Elvis; Zucchini Silvia; Trapella Claudio; Salvadori Severo; Beani Lorenzo; Bianchi Clementina; Morari Michele
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex.
The European journal of neuroscience 2004;19(5):1317-24.
2004: Salvadori Severo; Temussi Piero A
Antagonism in opioid peptides: the role of conformation.
Current topics in medicinal chemistry 2004;4(1):145-57.
2003: Balboni Gianfranco; Salvadori Severo; Guerrini Remo; Negri Lucia; Giannini Elisa; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Synthesis and opioid activity of N,N-dimethyl-Dmt-Tic-NH-CH(R)-R' analogues: acquisition of potent delta antagonism.
Bioorganic & medicinal chemistry 2003;11(24):5435-41.
2003: Okada Yoshio; Tsuda Yuko; Fujita Yoshio; Yokoi Toshio; Sasaki Yusuke; Ambo Akihiro; Konishi Ryoji; Nagata Mitsuhiro; Salvadori Severo; Jinsmaa Yunden; Bryant Sharon D; Lazarus Lawrence H
Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesia.
Journal of medicinal chemistry 2003;46(15):3201-9.
2003: Ingman Kimmo; Salvadori Severo; Lazarus Larry; Korpi Esa R; Honkanen Aapo
Selective delta-opioid receptor antagonist N,N(CH3)2-Dmt-Tic-OH does not reduce ethanol intake in alcohol-preferring AA rats.
Addiction biology 2003;8(2):173-9.
2003: Gavioli E C; Marzola G; Guerrini R; Bertorelli R; Zucchini S; De Lima T C M; Rae G A; Salvadori S; Regoli D; Calo G
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test.
The European journal of neuroscience 2003;17(9):1987-90.
2003: Tognetto Michele; D'Andrea Michael R; Trevisani Marcello; Guerrini Remo; Salvadori Severo; Spisani Lorella; Daniele Carlo; Andrade-Gordon Patricia; Geppetti Pierangelo; Harrison Selena
Proteinase-activated receptor-1 (PAR-1) activation contracts the isolated human renal artery in vitro.
British journal of pharmacology 2003;139(1):21-7.
2003: Lazzeri Massimo; Calò Girolamo; Spinelli Michele; Guerrini Remo; Salvadori Severo; Beneforti Patrizia; Sandri Sandro; Regoli Domenico; Turini Damiano
Urodynamic effects of intravesical nociceptin/orphanin FQ in neurogenic detrusor overactivity: a randomized, placebo-controlled, double-blind study.
Urology 2003;61(5):946-50.
2003: Guerrini Remo; Rizzi Daniela; Zucchini Marina; Tomatis Roberto; Regoli Domenico; Calo' Girolamo; Salvadori Severo
Nociceptin/Orphanin FQ(1-13)NH2 analogues modified in the Phe1-Gly2 peptide bond.
Bioorganic & medicinal chemistry letters 2003;13(3):365-8.
2003: Bryant Sharon D; Jinsmaa Yunden; Salvadori Severo; Okada Yoshio; Lazarus Lawrence H
Dmt and opioid peptides: a potent alliance.
Biopolymers 2003;71(2):86-102.
2002: Balboni Gianfranco; Salvadori Severo; Guerrini Remo; Negri Lucia; Giannini Elisa; Jinsmaa Yunden; Bryant Sharon D; Lazarus Lawrence H
Potent delta-opioid receptor agonists containing the Dmt-Tic pharmacophore.
Journal of medicinal chemistry 2002;45(25):5556-63.
2002: Bryant Sharon D; George Clifford; Flippen-Anderson Judith L; Deschamps Jeffrey R; Salvadori Severo; Balboni Gianfranco; Guerrini Remo; Lazarus Lawrence H
Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.
Journal of medicinal chemistry 2002;45(25):5506-13.
2002: Crescenzi Orlando; Tomaselli Simona; Guerrini Remo; Salvadori Severo; D'Ursi Anna M; Temussi Piero Andrea; Picone Delia
Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain.
European journal of biochemistry / FEBS 2002;269(22):5642-8.
2002: Camarda Valeria; Guerrini Remo; Kostenis Evi; Rizzi Anna; Calò Girolamo; Hattenberger Almut; Zucchini Marina; Salvadori Severo; Regoli Domenico
A new ligand for the urotensin II receptor.
British journal of pharmacology 2002;137(3):311-4.
2002: Amodeo Pietro; Guerrini Remo; Picone Delia; Salvadori Severo; Spadaccini Roberta; Tancredi Teodorico; Temussi Piero A
Solution structure of nociceptin peptides.
Journal of peptide science : an official publication of the European Peptide Society 2002;8(9):497-509.
2002: Rizzi Anna; Salis Maria Bonaria; Ciccocioppo Roberto; Marzola Giuliano; Bigoni Raffaella; Guerrini Remo; Massi Maurizio; Madeddu Paolo; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)NH2 analogues. 2. In vivo studies.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(6):450-6.
2002: Bigoni Raffaella; Rizzi Daniela; Rizzi Anna; Camarda Valeria; Guerrini Remo; Lambert David G; Hashiba Eiji; Berger Hartmut; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)amide analogues. 1. In vitro studies.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(6):442-9.
2002: Camarda V; Rizzi A; Calo G; Guerrini R; Salvadori S; Regoli D
Pharmacological profile of hemokinin 1: a novel member of the tachykinin family.
Life sciences 2002;71(4):363-70.
2002: Severini Cinzia; Improta Giovanna; Falconieri-Erspamer Giuliana; Salvadori Severo; Erspamer Vittorio
The tachykinin peptide family.
Pharmacological reviews 2002;54(2):285-322.
2002: Calo Girolamo; Rizzi Anna; Rizzi Daniela; Bigoni Raffaella; Guerrini Remo; Marzola Giuliano; Marti Matteo; McDonald John; Morari Michele; Lambert David G; Salvadori Severo; Regoli Domenico
[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.
British journal of pharmacology 2002;136(2):303-11.
2002: Calo' Girolamo; Rizzi Anna; Bigoni Raffaella; Guerrini Remo; Salvadori Severo; Regoli Domenico
Pharmacological profile of nociceptin/orphanin FQ receptors.
Clinical and experimental pharmacology & physiology 2002;29(3):223-8.
2002: Politou Anastasia S; Spadaccini Roberta; Joseph Catherine; Brannetti Barbara; Guerrini Remo; Helmer-Citterich Manuela; Salvadori Severo; Temussi Piero Andrea; Pastore Annalisa
The SH3 domain of nebulin binds selectively to type II peptides: theoretical prediction and experimental validation.
Journal of molecular biology 2002;316(2):305-15.
2002: Ciccocioppo Roberto; Polidori Carlo; Antonelli Lorena; Salvadori Severo; Guerrini Remo; Massi Maurizio
Pharmacological characterization of the nociceptin receptor which mediates reduction of alcohol drinking in rats.
Peptides 2002;23(1):117-25.
2002: Balboni Gianfranco; Guerrini Remo; Salvadori Severo; Bianchi Clementina; Rizzi Daniela; Bryant Sharon D; Lazarus Lawrence H
Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties.
Journal of medicinal chemistry 2002;45(3):713-20.
2001: Di Giannuario A; Rizzi A; Pieretti S; Guerrini R; Bertorelli R; Salvadori S; Regoli D; Calo G
Studies on the antinociceptive effect of [Nphe1]nociceptin(1-13)NH2 in mice.
Neuroscience letters 2001;316(1):25-8.
2001: Guerrini R; Caló G; Bigoni R; Rizzi D; Rizzi A; Zucchini M; Varani K; Hashiba E; Lambert D G; Toth G; Borea P A; Salvadori S; Regoli D
Structure-activity studies of the Phe(4) residue of nociceptin(1-13)-NH(2): identification of highly potent agonists of the nociceptin/orphanin FQ receptor.
Journal of medicinal chemistry 2001;44(23):3956-64.
2001: Rizzi A; Marzola G; Bigoni R; Guerrini R; Salvadori S; Mogil J S; Regoli D; Calò G
Endogenous nociceptin signaling and stress-induced analgesia.
Neuroreport 2001;12(14):3009-13.
2001: Santagada V; Caliendo G; Severino B; Perissutti E; Ceccarelli F; Giusti L; Mazzoni M R; Salvadori S; Temussi P A
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists.
Journal of peptide science : an official publication of the European Peptide Society 2001;7(7):374-85.
2001: Lovekamp T; Cooper P S; Hardison J; Bryant S D; Guerrini R; Balboni G; Salvadori S; Lazarus L H
Inhibition of human multidrug resistance P-glycoprotein 1 by analogues of a potent delta-opioid antagonist.
Brain research 2001;902(1):131-4.
2001: Marastoni M; Bazzaro M; Salvadori S; Bortolotti F; Tomatis R
HIV-1 protease inhibitors containing an N-hydroxyamino acid core structure.
Bioorganic & medicinal chemistry 2001;9(4):939-45.
2001: Guerrini R; Calo' G; Bigoni R; Rizzi D; Regoli D; Salvadori S
Structure-activity relationship of [Nphe1]-NC-(1-13)-NH2, a pure and selective nociceptin/orphanin FQ receptor antagonist.
The journal of peptide research : official journal of the American Peptide Society 2001;57(3):215-22.
2001: Rizzi A; Bigoni R; Marzola G; Guerrini R; Salvadori S; Regoli D; Calo' G
Characterization of the locomotor activity-inhibiting effect of nociceptin/orphanin FQ in mice.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(2):161-5.
2000: Santagada V; Balboni G; Caliendo G; Guerrini R; Salvadori S; Bianchi C; Bryant S D; Lazarus L H
Assessment of substitution in the second pharmacophore of Dmt-Tic analogues.
Bioorganic & medicinal chemistry letters 2000;10(24):2745-8.
2000: Balboni G; Salvadori S; Guerrini R; Bianchi C; Santagada V; Calliendo G; Bryant S D; Lazarus L H
Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei.
Peptides 2000;21(11):1663-71.
2000: Severini C; Salvadori S; Guerrini R; Falconieri-Erspamer G; Mignogna G; Erspamer V
Parallel bioassay of 39 tachykinins on 11 smooth muscle preparations. Structure and receptor selectivity/affinity relationship.
Peptides 2000;21(11):1587-95.
2000: Rizzi A; Bigoni R; Marzola G; Guerrini R; Salvadori S; Regoli D; Calo G
The nociceptin/orphanin FQ receptor antagonist, [Nphe1]NC(1-13)NH2, potentiates morphine analgesia.
Neuroreport 2000;11(11):2369-72.
2000: Calo' G; Bigoni R; Rizzi A; Guerrini R; Salvadori S; Regoli D
Nociceptin/orphanin FQ receptor ligands.
Peptides 2000;21(7):935-47.
2000: Guerrini R; Calo' G; Rizzi A; Bigoni R; Rizzi D; Regoli D; Salvadori S
Structure-activity relationships of nociceptin and related peptides: comparison with dynorphin A.
Peptides 2000;21(7):923-33.
2000: Guerrini R; Caló G; Bigoni R; Rizzi A; Varani K; Toth G; Gessi S; Hashiba E; Hashimoto Y; Lambert D G; Borea P A; Tomatis R; Salvadori S; Regoli D
Further studies on nociceptin-related peptides: discovery of a new chemical template with antagonist activity on the nociceptin receptor.
Journal of medicinal chemistry 2000;43(15):2805-13.
2000: Ricciardolo F L; Steinhoff M; Amadesi S; Guerrini R; Tognetto M; Trevisani M; Creminon C; Bertrand C; Bunnett N W; Fabbri L M; Salvadori S; Geppetti P
Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways.
American journal of respiratory and critical care medicine 2000;161(5):1672-80.
2000: Calo' G; Guerrini R; Rizzi A; Salvadori S; Regoli D
Pharmacology of nociceptin and its receptor: a novel therapeutic target.
British journal of pharmacology 2000;129(7):1261-83.
2000: Calo' G; Guerrini R; Bigoni R; Rizzi A; Marzola G; Okawa H; Bianchi C; Lambert D G; Salvadori S; Regoli D
Characterization of [Nphe(1)]nociceptin(1-13)NH(2), a new selective nociceptin receptor antagonist.
British journal of pharmacology 2000;129(6):1183-93.
2000: Crescenzi O; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi P A
Solution structure of nocistatin, a new peptide analgesic.
Biopolymers 2000;53(3):257-64.
1999: Rizzi A; Bigoni R; Caló G; Guerrini R; Salvadori S; Regoli D
[Nphe(1)]nociceptin-(1-13)-NH(2) antagonizes nociceptin effects in the mouse colon.
European journal of pharmacology 1999;385(2-3):R3-5.
1999: Salvadori S; Guerrini R; Balboni G; Bianchi C; Bryant S D; Cooper P S; Lazarus L H
Further studies on the Dmt-Tic pharmacophore: hydrophobic substituents at the C-terminus endow delta antagonists to manifest mu agonism or mu antagonism.
Journal of medicinal chemistry 1999;42(24):5010-9.
1999: Salvadori S; Guerrini R; Calo G; Regoli D
Structure-activity studies on nociceptin/orphanin FQ: from full agonist, to partial agonist, to pure antagonist.
Farmaco (Società chimica italiana : 1989) 1999;54(11-12):810-25.
1999: Varani K; Rizzi A; Calo G; Bigoni R; Toth G; Guerrini R; Gessi S; Salvadori S; Borea P A; Regoli D
Pharmacology of [Tyr1]nociceptin analogs: receptor binding and bioassay studies.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(3):270-7.
1999: Marastoni M; Bazzaro M; Bortolotti F; Salvadori S; Tomatis R
Symmetry-based inhibitors of HIV-1 protease. Design, synthesis and preliminary structure-activity studies of acylated 2,3-diamino-1-hydroxypropanes and 2,4 diamino-1-hydroxybutanes.
European journal of medicinal chemistry 1999;34(7-8):651-7.
1999: Negri L; Lattanzi R; Borsodi A; Toth G; Salvadori S
Differential knockdown of delta-opioid receptor subtypes in the rat brain by antisense oligodeoxynucleotides targeting mRNA.
Antisense & nucleic acid drug development 1999;9(2):203-11.
1999: Bigoni R; Giuliani S; Calo' G; Rizzi A; Guerrini R; Salvadori S; Regoli D; Maggi C A
Characterization of nociceptin receptors in the periphery: in vitro and in vivo studies.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(3):160-7.
1999: Lazarus L H; Bryant S D; Cooper P S; Salvadori S
What peptides these deltorphins be.
Progress in neurobiology 1999;57(4):377-420.
1999: Marastoni M; Guerrini R; Balboni G; Salvadori S; Fantin G; Fogagnolo M; Lazarus L H; Tomatis R
Opioid deltorphin C analogues containing cis- or trans-2- or 3- or 4-aminocyclohexanecarboxylic acid residues.
Arzneimittel-Forschung 1999;49(1):6-12.
1999: Rizzi A; Calò G; Trevisani M; Tognetto M; Fabbri L; Mapp C; Guerrini R; Salvadori S; Regoli D; Geppetti P
Nociceptin receptor activation inhibits tachykinergic non adrenergic non cholinergic contraction of guinea pig isolated bronchus.
Life sciences 1999;64(13):PL157-63.
1998: Varani K; Calo G; Rizzi A; Merighi S; Toth G; Guerrini R; Salvadori S; Borea P A; Regoli D
Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships.
British journal of pharmacology 1998;125(7):1485-90.
1998: Calò G; Rizzi A; Marzola G; Guerrini R; Salvadori S; Beani L; Regoli D; Bianchi C
Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay.
British journal of pharmacology 1998;125(2):373-8.
1998: Calo' G; Guerrini R; Bigoni R; Rizzi A; Bianchi C; Regoli D; Salvadori S
Structure-activity study of the nociceptin(1-13)-NH2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist.
Journal of medicinal chemistry 1998;41(18):3360-6.
1998: Marastoni M; Bortolotti F; Salvadori S; Tomatis R
Structure-activity relationships of HIV-1 protease inhibitors containing gem-diaminoserine core unit.
Arzneimittel-Forschung 1998;48(6):709-12.
1998: Bryant S D; Salvadori S; Cooper P S; Lazarus L H
New delta-opioid antagonists as pharmacological probes.
Trends in pharmacological sciences 1998;19(2):42-6.
1998: Guerrini R; Capasso A; Marastoni M; Bryant S D; Cooper P S; Lazarus L H; Temussi P A; Salvadori S
Rational design of dynorphin A analogues with delta-receptor selectivity and antagonism for delta- and kappa-receptors.
Bioorganic & medicinal chemistry 1998;6(1):57-62.
1998: Guerrini R; Calo G; Rizzi A; Bigoni R; Bianchi C; Salvadori S; Regoli D
A new selective antagonist of the nociceptin receptor.
British journal of pharmacology 1998;123(2):163-5.
1997: Capasso A; Amodeo P; Balboni G; Guerrini R; Lazarus L H; Temussi P A; Salvadori S
Design of mu selective opioid dipeptide antagonists.
FEBS letters 1997;417(1):141-4.
1997: Salvadori S; Balboni G; Guerrini R; Tomatis R; Bianchi C; Bryant S D; Cooper P S; Lazarus L H
Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
Journal of medicinal chemistry 1997;40(19):3100-8.
1997: Tomatis R; Marastoni M; Balboni G; Guerrini R; Capasso A; Sorrentino L; Santagada V; Caliendo G; Lazarus L H; Salvadori S
Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides.
Journal of medicinal chemistry 1997;40(18):2948-52.
1997: Bryant S D; Guerrini R; Salvadori S; Bianchi C; Tomatis R; Attila M; Lazarus L H
Helix-inducing alpha-aminoisobutyric acid in opioid mimetic deltorphin C analogues.
Journal of medicinal chemistry 1997;40(16):2579-87.
1997: Crescenzi O; Fraternali F; Picone D; Tancredi T; Balboni G; Guerrini R; Lazarus L H; Salvadori S; Temussi P A
Design and solution structure of a partially rigid opioid antagonist lacking the basic center--models of antagonism.
European journal of biochemistry / FEBS 1997;247(1):66-73.
1997: Calò G; Rizzi A; Bodin M; Neugebauer W; Salvadori S; Guerrini R; Bianchi C; Regoli D
Pharmacological characterization of nociceptin receptor: an in vitro study.
Canadian journal of physiology and pharmacology 1997;75(6):713-8.
1997: Marastoni M; Salvadori S; Bortolotti F; Tomatis R
HIV-1 protease inhibitors containing a novel C2 symmetrical hydroxyalkylgem-diamino core structure.
The journal of peptide research : official journal of the American Peptide Society 1997;49(6):538-44.
1997: Guerrini R; Calo G; Rizzi A; Bianchi C; Lazarus L H; Salvadori S; Temussi P A; Regoli D
Address and message sequences for the nociceptin receptor: a structure-activity study of nociceptin-(1-13)-peptide amide.
Journal of medicinal chemistry 1997;40(12):1789-93.
1997: Salvadori S; Picone D; Tancredi T; Guerrini R; Spadaccini R; Lazarus L H; Regoli D; Temussi P A
Solution conformation of nociceptin.
Biochemical and biophysical research communications 1997;233(3):640-3.
1997: Bryant S D; Balboni G; Guerrini R; Salvadori S; Tomatis R; Lazarus L H
Opioid diketopiperazines: refinement of the delta opioid antagonist pharmacophore.
Biological chemistry 1997;378(2):107-14.
1997: Balboni G; Guerrini R; Salvadori S; Tomatis R; Bryant S D; Bianchi C; Attila M; Lazarus L H
Opioid diketopiperazines: synthesis and activity of a prototypic class of opioid antagonists.
Biological chemistry 1997;378(1):19-29.
1996: Crescenzi O; Amodeo P; Cavicchioni G; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi P A
Delta-selective opioid peptides containing a single aromatic residue in the message domain: an NMR conformational analysis.
Journal of peptide science : an official publication of the European Peptide Society 1996;2(5):290-308.
1996: Calò G; Rizzi A; Bogoni G; Neugebauer V; Salvadori S; Guerrini R; Bianchi C; Regoli D
The mouse vas deferens: a pharmacological preparation sensitive to nociceptin.
European journal of pharmacology 1996;311(1):R3-5.
1996: Guerrini R; Capasso A; Sorrentino L; Anacardio R; Bryant S D; Lazarus L H; Attila M; Salvadori S
Opioid receptor selectivity alteration by single residue replacement: synthesis and activity profile of [Dmt1]deltorphin B.
European journal of pharmacology 1996;302(1-3):37-42.
1996: Breveglieri A; Guerrini R; Salvadori S; Bianchi C; Bryant S D; Attila M; Lazarus L H
Design and synthesis of 1-aminocycloalkane-1-carboxylic acid-substituted deltorphin analogues: unique delta and mu opioid activity in modified peptides.
Journal of medicinal chemistry 1996;39(3):773-80.
1996: Lazarus L H; Bryant S D; Salvadori S; Attila M; Sargent Jones L
Opioid infidelity: novel opioid peptides with dual high affinity for delta- and mu-receptors.
Trends in neurosciences 1996;19(1):31-5.
1996: Capasso A; Guerrini R; Balboni G; Sorrentino L; Temussi P; Lazarus L H; Bryant S D; Salvadori S
Dmt-Tic-OH a highly selective and potent delta-opioid dipeptide receptor antagonist after systemic administration in the mouse.
Life sciences 1996;59(8):PL93-8.
1995: Amodeo P; Balboni G; Crescenzi O; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi P A
Conformational analysis of potent and very selective delta opioid dipeptide antagonists.
FEBS letters 1995;377(3):363-7.
1995: Salvadori S; Attila M; Balboni G; Bianchi C; Bryant S D; Crescenzi O; Guerrini R; Picone D; Tancredi T; Temussi P A
Delta opioidmimetic antagonists: prototypes for designing a new generation of ultraselective opioid peptides.
Molecular medicine (Cambridge, Mass.) 1995;1(6):678-89.
1995: Ciajolo M R; Balboni G; Picone D; Salvadori S; Tancredi T; Temussi P A; Tuzi A
Solution and solid-state structure of the diketopiperazine of tyrosyl-tetrahydroisoquinoline-3-carboxylic acid.
International journal of peptide and protein research 1995;46(2):134-8.
1995: degli Uberti E C; Salvadori S; Trasforini G; Ambrosio M R; Margutti A; Bondanelli M; Rossi R; Valentini A
Differential effects of deltorphin on arginine and galanin-induced growth hormone secretion in healthy man.
Regulatory peptides 1995;58(1-2):41-6.
1995: Capasso S; Sica F; Mazzarella L; Balboni G; Guerrini R; Salvadori S
Acid catalysis in the formation of dioxopiperazines from peptides containing tetrahydroisoquinoline-3-carboxylic acid at position 2.
International journal of peptide and protein research 1995;45(6):567-73.
1995: Balboni G; Salvadori S; D'Angeli F; Marchetti P; Lazarus L H; Bryant S D; Bianchi C
Single diastereomeric desaminotyrosylalanyl tetra- and heptapeptides with opioid antagonistic activity.
International journal of peptide and protein research 1995;45(2):187-93.
1995: Marastoni M; Salvadori S; Balboni G; Scaranari V; Borea P A; Tomatis A
Synthesis and opioid activity of tyrosine sulfate containing dermorphin and deltorphin peptides.
Arzneimittel-Forschung 1995;45(2):116-9.
1995: degli Uberti E C; Petraglia F; Bondanelli M; Guo A L; Valentini A; Salvadori S; Criscuolo M; Nappi R E; Genazzani A R
Involvement of mu-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats.
Journal of endocrinological investigation 1995;18(1):1-7.
1994: Marastoni M; Salvadori S; Scaranari V; Spisani S; Reali E; Traniello S; Tomatis A
Synthesis and activity of new linear and cyclic peptide T derivatives.
Arzneimittel-Forschung 1994;44(9):1073-6.
1994: Tancredi T; Salvadori S; Amodeo P; Picone D; Lazarus L H; Bryant S D; Guerrini R; Marzola G; Temussi P A
Conversion of enkephalin and dermorphin into delta-selective opioid antagonists by single-residue substitution.
European journal of biochemistry / FEBS 1994;224(1):241-7.
1994: Lazarus L H; Bryant S D; Attila M; Salvadori S
Frog skin opioid peptides: a case for environmental mimicry.
Environmental health perspectives 1994;102(8):648-54.
1994: Bryant S D; Attila M; Salvadori S; Guerrini R; Lazarus L H
Molecular dynamics conformations of deltorphin analogues advocate delta opioid binding site models.
Peptide research 1994;7(4):175-84.
1994: Temussi P A; Salvadori S; Amodeo P; Bianchi C; Guerrini R; Tomatis R; Lazarus L H; Picone D; Tancredi T
Selective opioid dipeptides.
Biochemical and biophysical research communications 1994;198(3):933-9.
1993: degli Uberti E C; Ambrosio M R; Vergnani L; Portaluppi F; Bondanelli M; Trasforini G; Margutti A; Salvadori S
Stress-induced activation of sympathetic nervous system is attenuated by the delta-opioid receptor agonist deltorphin in healthy man.
The Journal of clinical endocrinology and metabolism 1993;77(6):1490-4.
1993: Attila M; Salvadori S; Balboni G; Bryant S D; Lazarus L H
Synthesis and receptor binding analysis of dermorphin hepta-, hexa- and pentapeptide analogues. Evidence for one- and two-side binding models for the mu-opioid receptor.
International journal of peptide and protein research 1993;42(6):550-9.
1993: Salvadori S; Bryant S D; Bianchi C; Balboni G; Scaranari V; Attila M; Lazarus L H
Phe3-substituted analogues of deltorphin C. Spatial conformation and topography of the aromatic ring in peptide recognition by delta opioid receptors.
Journal of medicinal chemistry 1993;36(24):3748-56.
1993: Marastoni M; Salvadori S; Balboni G; Scaranari V; Spisani S; Reali E; Traniello S; Tomatis R
Structure-activity relationships of cyclic and linear peptide T analogues.
International journal of peptide and protein research 1993;41(5):447-54.
1993: Fontani G; Vergnani L; Salvadori S; Voglino N; Aloisi A M; Portaluppi F; Degli Uberti E C
Effect of deltorphin on behavior and hippocampal electrical activity in rabbits.
Physiology & behavior 1993;53(2):285-90.
1993: Lazarus L H; Salvadori S; Attila M; Grieco P; Bundy D M; Wilson W E; Tomatis R
Interaction of deltorphin with opioid receptors: molecular determinants for affinity and selectivity.
Peptides 1993;14(1):21-8.
1993: Salvadori S; Bryant S D; Temussi P A; Bundy D M; Attila M; Tomatis R; Lazarus L H
Relationship between receptor affinity and topography of N-terminally extended and bridged [Tyr1-->Asp4]deltorphin C analogues: novel probes for the delta-opioid receptor.
European journal of pharmacology 1993;230(3):357-61.
1993: Fontani G; Vergnani L; Salvadori S; Voglino N; Aloisi A M; Portaluppi F; degli Uberti E C
Effect of dermorphin on behavior and hippocampal electrical activity in rabbits.
Life sciences 1993;52(3):323-8.
1992: degli Uberti E C; Salvadori S; Trasforini G; Margutti A; Ambrosio M R; Rossi R; Portaluppi F; Vergnani L; Pansini R
delta-Opioid receptors and the secretion of growth hormone in man: effect of opioid delta-receptor agonist deltorphin on GH responses to GH-releasing hormone and insulin-induced hypoglycemia.
Neuroendocrinology 1992;56(6):907-12.
1992: Salvadori S; Bianchi C; Lazarus L H; Scaranari V; Attila M; Tomatis R
Para-substituted Phe3 deltorphin analogues: enhanced selectivity of halogenated derivatives for delta opioid receptor sites.
Journal of medicinal chemistry 1992;35(25):4651-7.
1992: Salvadori S; Guerrini R; Borea P A; Tomatis R
Synthesis and pharmacological activity of the N-terminal dermorphin tetrapeptide analogs with CH2-NH peptide bond isosteres.
International journal of peptide and protein research 1992;40(5):437-44.
1992: Degli Uberti E C; Salvadori S; Trasforini G; Margutti A; Ambrosio M R; Rossi R; Portaluppi F; Pansini R
Effect of deltorphin on pituitary-adrenal response to insulin-induced hypoglycemia and ovine corticotropin-releasing hormone in healthy man.
The Journal of clinical endocrinology and metabolism 1992;75(2):370-4.
1992: Temussi P A; Picone D; Saviano G; Amodeo P; Motta A; Tancredi T; Salvadori S; Tomatis R
Conformational analysis of an opioid peptide in solvent media that mimic cytoplasm viscosity.
Biopolymers 1992;32(4):367-72.
1992: Lazarus L H; Salvadori S; Balboni G; Tomatis R; Wilson W E
Stereospecificity of amino acid side chains in deltorphin defines binding to opioid receptors.
Journal of medicinal chemistry 1992;35(7):1222-7.
1992: Amodeo P; Motta A; Tancredi T; Salvadori S; Tomatis R; Picone D; Saviano G; Temussi P A
Solution structure of deltorphin I at 265 K: a quantitative NMR study.
Peptide research 1992;5(1):48-55.
1991: Marastoni M; Scaranari V; Salvadori S; Tomatis R; Spisani S; Traniello S
Synthesis and antiaggregatory activity of antiflammin related peptides.
Farmaco (Società chimica italiana : 1989) 1991;46(11):1265-72.
1991: Marastoni M; Tomatis R; Balboni G; Salvadori S; Lazarus L H
On the degradation of the deltorphin peptides by plasma and brain homogenate.
Farmaco (Società chimica italiana : 1989) 1991;46(11):1273-9.
1991: Lazarus L H; Salvadori S; Tomatis R; Wilson W E
Opioid receptor selectivity reversal in deltorphin tetrapeptide analogues.
Biochemical and biophysical research communications 1991;178(1):110-5.
1991: Tancredi T; Temussi P A; Picone D; Amodeo P; Tomatis R; Salvadori S; Marastoni M; Santagada V; Balboni G
New insights on mu/delta selectivity of opioid peptides: conformational analysis of deltorphin analogues.
Biopolymers 1991;31(6):751-60.
1991: Salvadori S; Marastoni M; Balboni G; Borea P A; Morari M; Tomatis R
Synthesis and structure-activity relationships of deltorphin analogues.
Journal of medicinal chemistry 1991;34(5):1656-61.
1991: Lazarus L H; Salvadori S; Santagada V; Tomatis R; Wilson W E
Function of negative charge in the "address domain" of deltorphins.
Journal of medicinal chemistry 1991;34(4):1350-5.
1991: Marastoni M; Salvadori S; Balboni G; Scaranari V; Santagada V; Romualdi P; Ferri S; Tomatis R
Studies on the anti-phospholipase A2 and anti-inflammatory activities of a synthetic nonapeptide from uteroglobin.
Arzneimittel-Forschung 1991;41(3):240-3.
1990: Balboni G; Marastoni M; Picone D; Salvadori S; Tancredi T; Temussi P A; Tomatis R
New features of the delta opioid receptor: conformational properties of deltorphin I analogues.
Biochemical and biophysical research communications 1990;169(2):617-22.
1990: Marastoni M; Salvadori S; Balboni G; Spisani S; Gavioli R; Traniello S; Tomatis R
Synthesis, metabolic stability and chemotactic activity of peptide T and its analogues.
International journal of peptide and protein research 1990;35(2):81-8.
1989: Marastoni M; Balboni G; Tomatis R; Salvadori S; Borea P A; Uccelli L
Opioid peptides. Partially modified retro-inverso dermorphin analogues. XIII.
Farmaco (Società chimica italiana : 1989) 1989;44(11):1083-93.
1989: Marastoni M; Salvadori S; Balboni G; Spisani S; Gavioli R; Traniello S; Tomatis R
Structure-activity relationships of peptide T-related pentapeptides.
Arzneimittel-Forschung 1989;39(8):926-8.
1989: Marastoni M; Salvadori S; Balboni G; Borea P A; Tomatis R
Synthesis and activity of dermorphin-growth hormone releasing factor hybrid peptides.
Arzneimittel-Forschung 1989;39(6):639-41.
1989: Temussi P A; Picone D; Tancredi T; Tomatis R; Salvadori S; Marastoni M; Balboni G
Conformational properties of deltorphin: new features of the delta-opioid receptor.
FEBS letters 1989;247(2):283-8.
1989: Salvadori S; Marastoni M; Balboni G; Borea P; Tomatis R
Opioid peptides. Synthesis and binding properties of dermorphin related heptapeptides.
International journal of peptide and protein research 1989;33(2):94-102.
1989: Castiglione-Morelli M A; Saviano G; Temussi P A; Balboni G; Salvadori S; Tomatis R
NMR studies of a series of dehydrodermorphins.
Biopolymers 1989;28(1):129-38.
1988: Castiglione-Morelli M A; Tancredi T; Trivellone E; Balboni G; Marastoni M; Salvadori S; Tomatis R; Temussi P A
Structure-activity relationship of tetrapeptides related to dermorphin: a 500-MHz 1H-nmr study.
Biopolymers 1988;27(9):1353-61.
1987: Salvadori S; Marastoni M; Balboni G; Tomatis R; Borea P A
Opioid peptides. Synthesis and binding assays of desamino-Tyr1 dermorphin analogues. XII.
Il Farmaco; edizione scientifica 1987;42(12):931-40.
1987: Castiglione-Morelli M A; Lelj F; Pastore A; Salvadori S; Tancredi T; Tomatis R; Trivellone E; Temussi P A
A 500-MHz proton nuclear magnetic resonance study of mu opioid peptides in a simulated receptor environment.
Journal of medicinal chemistry 1987;30(11):2067-73.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Severo Salvadori

Research Profile (preview)

Chemicals & Drugs

Concepts & Ideas

Living Beings

Genes & Molecular Sequences

Anatomy

Physiology

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Severo Salvadori (preview)

All Publications