FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Christopher Salvatore

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Migraine Disorders

Concepts & Ideas

Co-author Network

Publications

TOP 3
Ian M Bell; Joseph G Bruno; Amy Calamari; Christine Fandozzi; Steven N Gallicchio; Samuel L Graham; Stefanie A Kane; Amanda L Kemmerer; Eric L Moore; Scott D Mosser; Nova Sain; Harold G Selnick; Donnette D Staas; Craig A Stump; Mark Urban; Joseph P Vacca; Rebecca B White; C Blair Zartman; Matthew M Zrada; Christopher A Salvatore
MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.
Eric L Moore; Christopher A Salvatore
Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.
C Blair Zartman; Ian M Bell; Steven N Gallicchio; Samuel L Graham; Stefanie A Kane; John J Mallee; Ruth Z Rutledge; Christopher A Salvatore; Joseph P Vacca; Theresa M Williams
Identification of a novel RAMP-independent CGRP receptor antagonist.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Christopher Salvatore (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Ian M Bell; Joseph G Bruno; Amy Calamari; Christine Fandozzi; Steven N Gallicchio; Samuel L Graham; Stefanie A Kane; Amanda L Kemmerer; Eric L Moore; Scott D Mosser; Nova Sain; Harold G Selnick; Donnette D Staas; Craig A Stump; Mark Urban; Joseph P Vacca; Rebecca B White; C Blair Zartman; Matthew M Zrada; Christopher A Salvatore
MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.
Bioorganic & medicinal chemistry letters 2012;22(12):3941-5.
2012: Eric L Moore; Christopher A Salvatore
Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.
British journal of pharmacology 2012;166(1):66-78.
2011: C Blair Zartman; Ian M Bell; Steven N Gallicchio; Samuel L Graham; Stefanie A Kane; John J Mallee; Ruth Z Rutledge; Christopher A Salvatore; Joseph P Vacca; Theresa M Williams
Identification of a novel RAMP-independent CGRP receptor antagonist.
Bioorganic & medicinal chemistry letters 2011;21(22):6705-8.
2011: Christopher A Salvatore; Stefanie A Kane
CGRP receptor antagonists: toward a novel migraine therapy.
Current pharmaceutical biotechnology 2011;12(10):1671-80.
2011: Daniel V Paone; Diem N Nguyen; Anthony W Shaw; Christopher S Burgey; Craig M Potteiger; James Z Deng; Scott D Mosser; Christopher A Salvatore; Sean Yu; Shane Roller; Stefanie A Kane; Harold G Selnick; Joseph P Vacca; Theresa M Williams
Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918.
Bioorganic & medicinal chemistry letters 2011;21(9):2683-6.
2010: Michael R Wood; Kathy M Schirripa; June J Kim; Rodney A Bednar; John F Fay; Joseph G Bruno; Eric L Moore; Scott D Mosser; Shane Roller; Christopher A Salvatore; Joseph P Vacca; Harold G Selnick
Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chirality.
Bioorganic & medicinal chemistry letters 2010;20(22):6827-30.
2010: Craig A Stump; Ian M Bell; Rodney A Bednar; John F Fay; Steven N Gallicchio; James C Hershey; Richard Jelley; Constantine Kreatsoulas; Eric L Moore; Scott D Mosser; Amy G Quigley; Shane A Roller; Christopher A Salvatore; Steven S Sharik; Cory R Theberge; C Blair Zartman; Stefanie A Kane; Samuel L Graham; Harold G Selnick; Joseph P Vacca; Theresa M Williams
Identification of potent, highly constrained CGRP receptor antagonists.
Bioorganic & medicinal chemistry letters 2010;20(8):2572-6.
2010: Christopher A Salvatore; Eric L Moore; Amy Calamari; Jacquelynn J Cook; Maria S Michener; Stacey O'Malley; Patricia J Miller; Cyrille Sur; David L Williams; Zhizhen Zeng; Andrew Danziger; Joseph J Lynch; Christopher P Regan; John F Fay; Yui S Tang; Chi-Chung Li; Nicole T Pudvah; Rebecca B White; Ian M Bell; Steven N Gallicchio; Samuel L Graham; Harold G Selnick; Joseph P Vacca; Stefanie A Kane
Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist.
The Journal of pharmacology and experimental therapeutics 2010;333(1):152-60.
2009: Christopher S Burgey; Craig M Potteiger; James Z Deng; Scott D Mosser; Christopher A Salvatore; Sean Yu; Shane Roller; Stefanie A Kane; Joseph P Vacca; Theresa M Williams
Optimization of azepanone calcitonin gene-related peptide (CGRP) receptor antagonists: development of novel spiropiperidines.
Bioorganic & medicinal chemistry letters 2009;19(22):6368-72.
2009: Ian M Bell; Rodney A Bednar; Halea A Corcoran; John F Fay; Steven N Gallicchio; Victor K Johnston; James C Hershey; Cynthia Miller-Stein; Eric L Moore; Scott D Mosser; Shane A Roller; Christopher A Salvatore; Cory R Theberge; Bradley K Wong; C Blair Zartman; Stefanie A Kane; Theresa M Williams; Samuel L Graham; Joseph P Vacca
The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.
Bioorganic & medicinal chemistry letters 2009;19(16):4740-2.
2009: Eric L Moore; Christopher S Burgey; Daniel V Paone; Anthony W Shaw; Yui S Tang; Stefanie A Kane; Christopher A Salvatore
Examining the binding properties of MK-0974: a CGRP receptor antagonist for the acute treatment of migraine.
European journal of pharmacology 2009;602(2-3):250-4.
2009: Theresa M Williams; Christopher S Burgey; Christopher A Salvatore
Calcitonin gene-related peptide receptor antagonists for the treatment of migraine.
Progress in medicinal chemistry 2009;47():1-35.
2008: Christopher A Salvatore; James C Hershey; Halea A Corcoran; John F Fay; Victor K Johnston; Eric L Moore; Scott D Mosser; Christopher S Burgey; Daniel V Paone; Anthony W Shaw; Samuel L Graham; Joseph P Vacca; Theresa M Williams; Kenneth S Koblan; Stefanie A Kane
Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine.
The Journal of pharmacology and experimental therapeutics 2008;324(2):416-21.
2008: Diem N Nguyen; Daniel V Paone; Anthony W Shaw; Christopher S Burgey; Scott D Mosser; Victor Johnston; Christopher A Salvatore; Yvonne M Leonard; Cynthia Miller-Stein; Stefanie A Kane; Kenneth S Koblan; Joseph P Vacca; Samuel L Graham; Theresa M Williams
Calcitonin gene-related peptide (CGRP) receptor antagonists: investigations of a pyridinone template.
Bioorganic & medicinal chemistry letters 2008;18(2):755-8.
2007: Daniel V Paone; Anthony W Shaw; Diem N Nguyen; Christopher S Burgey; James Z Deng; Stefanie A Kane; Kenneth S Koblan; Christopher A Salvatore; Scott D Mosser; Victor K Johnston; Bradley K Wong; Cynthia Miller-Stein; James C Hershey; Samuel L Graham; Joseph P Vacca; Theresa M Williams
Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine: discovery of N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974).
Journal of medicinal chemistry 2007;50(23):5564-7.
2007: Anthony W Shaw; Daniel V Paone; Diem N Nguyen; Craig A Stump; Christopher S Burgey; Scott D Mosser; Christopher A Salvatore; Ruth Z Rutledge; Stefanie A Kane; Kenneth S Koblan; Samuel L Graham; Joseph P Vacca; Theresa M Williams
Caprolactams as potent CGRP receptor antagonists for the treatment of migraine.
Bioorganic & medicinal chemistry letters 2007;17(17):4795-8.
2006: Ian M Bell; Rodney A Bednar; John F Fay; Steven N Gallicchio; Jerome H Hochman; Daniel R McMasters; Cynthia Miller-Stein; Eric L Moore; Scott D Mosser; Nicole T Pudvah; Amy G Quigley; Christopher A Salvatore; Craig A Stump; Cory R Theberge; Bradley K Wong; C Blair Zartman; Xu-Fang Zhang; Stefanie A Kane; Samuel L Graham; Joseph P Vacca; Theresa M Williams
Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonists.
Bioorganic & medicinal chemistry letters 2006;16(24):6165-9.
2006: Christopher S Burgey; Craig A Stump; Diem N Nguyen; James Z Deng; Amy G Quigley; Beth R Norton; Ian M Bell; Scott D Mosser; Christopher A Salvatore; Ruth Z Rutledge; Stefanie A Kane; Kenneth S Koblan; Joseph P Vacca; Samuel L Graham; Theresa M Williams
Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: optimization of the 4-substituted piperidine.
Bioorganic & medicinal chemistry letters 2006;16(19):5052-6.
2006: Theresa M Williams; Craig A Stump; Diem N Nguyen; Amy G Quigley; Ian M Bell; Steven N Gallicchio; C Blair Zartman; Bang-Lin Wan; Kimberly Della Penna; Priya Kunapuli; Stefanie A Kane; Kenneth S Koblan; Scott D Mosser; Ruth Z Rutledge; Christopher A Salvatore; John F Fay; Joseph P Vacca; Samuel L Graham
Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead.
Bioorganic & medicinal chemistry letters 2006;16(10):2595-8.
2006: Christopher A Salvatore; John J Mallee; Ian M Bell; C Blair Zartman; Theresa M Williams; Kenneth S Koblan; Stefanie A Kane
Identification and pharmacological characterization of domains involved in binding of CGRP receptor antagonists to the calcitonin-like receptor.
Biochemistry 2006;45(6):1881-7.
2005: James C Hershey; Halea A Corcoran; Elizabeth P Baskin; Christopher A Salvatore; Scott D Mosser; Theresa M Williams; Kenneth S Koblan; Richard Hargreaves; Stefanie A Kane
Investigation of the species selectivity of a nonpeptide CGRP receptor antagonist using a novel pharmacodynamic assay.
Regulatory peptides 2005;127(1-3):71-7.
2002: John J Mallee; Christopher A Salvatore; Beatrice LeBourdelles; Kevin R Oliver; Jenny Longmore; Kenneth S Koblan; Stefanie A Kane
Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists.
The Journal of biological chemistry 2002;277(16):14294-8.
2001: Kevin R Oliver; Stefanie A Kane; Christopher A Salvatore; John J Mallee; AM Kinsey; Kenneth S Koblan; N Keyvan-Fouladi; Robert P Heavens; Anna Wainwright; M Jacobson; Ian M Dickerson; Raymond G Hill
Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat.
The European journal of neuroscience 2001;14(4):618-28.
2000: Christopher A Salvatore; Stephen L Tilley; Anne M Latour; Daniel S Fletcher; Beverly H Koller; Marlene A Jacobson
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells.
The Journal of biological chemistry 2000;275(6):4429-34.
2000: Stephen L Tilley; V A Wagoner; Christopher A Salvatore; Marlene A Jacobson; Beverly H Koller
Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells.
The Journal of clinical investigation 2000;105(3):361-7.
1999: Peter D Williams; Mark G Bock; BE Evans; Roger M Freidinger; Steven N Gallicchio; MT Guidotti; Marlene A Jacobson; Michelle Kuo; M R Levy; Edward V Lis; Stuart R Michelson; Joseph M Pawluczyk; Debra S Perlow; Douglas J Pettibone; Amy G Quigley; Duane R Reiss; Christopher A Salvatore; Kenneth J Stauffer; CJ Woyden
Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency.
Bioorganic & medicinal chemistry letters 1999;9(9):1311-6.
1998: Christopher A Salvatore; CJ Woyden; MT Guidotti; Douglas J Pettibone; Marlene A Jacobson
Cloning and expression of the rhesus monkey oxytocin receptor.
Journal of receptor and signal transduction research 1998;18(1):15-24.