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Giuliana Salvatore

Research Profile

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Roberto Bellelli; Maria Carmela Cantisani; Maria Domenica Castellone; Tomas Alvarez Gago; Ginesa Garcia-Rostan; Tito Claudio Nappi; Carmelo Nucera; Peter M Sadow; Paolo Salerno; Giuliana Salvatore; Fulvio Basolo; Clara Ugolini; Massimo Santoro
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.
Katrin-Janine Heiliger; Julia Hess; Paolo Salerno; Giuliana Salvatore; Massimo Santoro; Isolde Summerer; Gerry Thomas; Clara Ugolini; Kristian Unger; Donata Vitagliano; Tatjana Bogdanova; Herbert Braselmann; Horst Zitzelsberger
Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.
Raffaella Faraonio; A Iaccio; Tito Claudio Nappi; F Passaro; Simona Romano; Paolo Salerno; Giuliana Salvatore; Massimo Santoro; C Sedia; R Bellelli; M Comegna; Filiberto Cimino
A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts.

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All Publications

2012: Roberto Bellelli; Maria Carmela Cantisani; Maria Domenica Castellone; Tomas Alvarez Gago; Ginesa Garcia-Rostan; Tito Claudio Nappi; Carmelo Nucera; Peter M Sadow; Paolo Salerno; Giuliana Salvatore; Fulvio Basolo; Clara Ugolini; Massimo Santoro
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.
Endocrine-related cancer 2012;19(5):695-710.
2012: Katrin-Janine Heiliger; Julia Hess; Paolo Salerno; Giuliana Salvatore; Massimo Santoro; Isolde Summerer; Gerry Thomas; Clara Ugolini; Kristian Unger; Donata Vitagliano; Tatjana Bogdanova; Herbert Braselmann; Horst Zitzelsberger
Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.
Endocrine-related cancer 2012;19(3):409-21.
2012: Raffaella Faraonio; A Iaccio; Tito Claudio Nappi; F Passaro; Simona Romano; Paolo Salerno; Giuliana Salvatore; Massimo Santoro; C Sedia; R Bellelli; M Comegna; Filiberto Cimino
A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts.
Cell death and differentiation 2012;19(4):713-21.
2011: Paolo Salerno; Ginesa Garcia-Rostan; Sara Piccinin; Tammaro Claudio Bencivenga; Gennaro Di Maro; Claudio Doglioni; Fulvio Basolo; Roberta Maestro; Alfredo Fusco; Massimo Santoro; Giuliana Salvatore
TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype.
The Journal of clinical endocrinology and metabolism 2011;96(5):E772-81.
2010: Paolo Salerno; Valentina De Falco; Anna Tamburrino; Tito Claudio Nappi; Giancarlo Vecchio; Rebecca E Schweppe; Gideon Bollag; Massimo Santoro; Giuliana Salvatore
Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells.
The Journal of clinical endocrinology and metabolism 2010;95(1):450-5.
2009: Marcello Mancini; Emilia Vergara; Giuliana Salvatore; Adelaide Greco; Giancarlo Troncone; Andrea Affuso; Raffaele Liuzzi; Paolo Salerno; Maria Scotto di Santolo; Massimo Santoro; Arturo Brunetti; Marco Salvatore
Morphological ultrasound microimaging of thyroid in living mice.
Endocrinology 2009;150(10):4810-5.
2009: Tito Claudio Nappi; Paolo Salerno; Horst Zitzelsberger; Francesca Carlomagno; Giuliana Salvatore; Massimo Santoro
Identification of Polo-like kinase 1 as a potential therapeutic target in anaplastic thyroid carcinoma.
Cancer research 2009;69(5):1916-23.
2008: Maria Domenica Castellone; Francesca Carlomagno; Giuliana Salvatore; Massimo Santoro
Receptor tyrosine kinase inhibitors in thyroid cancer.
Best practice & research. Clinical endocrinology & metabolism 2008;22(6):1023-38.
2008: Giuliana Salvatore; Francesca Carlomagno; Massimo Santoro
Pros and cons of cellular studies in developing new drugs for thyroid cancers.
Thyroid : official journal of the American Thyroid Association 2008;18(8):819-22.
2007: Valentina De Falco; Valentina Guarino; Elvira Avilla; Maria Domenica Castellone; Paolo Salerno; Giuliana Salvatore; Pinuccia Faviana; Fulvio Basolo; Massimo Santoro; Rosa Marina Melillo
Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer.
Cancer research 2007;67(24):11821-9.
2007: Giuliana Salvatore; Tito Claudio Nappi; Paolo Salerno; Yuan Jiang; Corrado Garbi; Clara Ugolini; Paolo Miccoli; Fulvio Basolo; Maria Domenica Castellone; Anna Maria Cirafici; Rosa Marina Melillo; Alfredo Fusco; Michael Bittner; Massimo Santoro
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.
Cancer research 2007;67(21):10148-58.
2007: Riccardo Giannini; Clara Ugolini; Cristiana Lupi; Agnese Proietti; Rossella Elisei; Giuliana Salvatore; Piero Berti; Gabriele Materazzi; Paolo Miccoli; Massimo Santoro; Fulvio Basolo
The heterogeneous distribution of BRAF mutation supports the independent clonal origin of distinct tumor foci in multifocal papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2007;92(9):3511-6.
2007: Clara Ugolini; Riccardo Giannini; Cristiana Lupi; Giuliana Salvatore; Paolo Miccoli; Agnese Proietti; Rossella Elisei; Massimo Santoro; Fulvio Basolo
Presence of BRAF V600E in very early stages of papillary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association 2007;17(5):381-8.
2006: Kerry J Rhoden; Kristian Unger; Giuliana Salvatore; Yesim Yilmaz; Volodymyr Vovk; Gennaro Chiappetta; Mazin B Qumsiyeh; Jay L Rothstein; Alfredo Fusco; Massimo Santoro; Horst Zitzelsberger; Giovanni Tallini
RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.
The Journal of clinical endocrinology and metabolism 2006;91(6):2414-23.
2006: Giuliana Salvatore; Valentina De Falco; Paolo Salerno; Tito Claudio Nappi; Stefano Pepe; Giancarlo Troncone; Francesca Carlomagno; Rosa Marina Melillo; Scott M Wilhelm; Massimo Santoro
BRAF is a therapeutic target in aggressive thyroid carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1623-9.
2006: Francesca Carlomagno; Suresh Anaganti; Teresa Guida; Giuliana Salvatore; Giancarlo Troncone; Scott M Wilhelm; Massimo Santoro
BAY 43-9006 inhibition of oncogenic RET mutants.
Journal of the National Cancer Institute 2006;98(5):326-34.
2005: Jorge Lima; Vítor Trovisco; Paula Soares; Valdemar Maximo; João Magalhães; Giuliana Salvatore; Massimo Santoro; Tetyana I Bogdanova; Mykola D Tronko; Alexander Abrosimov; Steve Jeremiah; Gerry Thomas; Dillwyn Williams; Manuel Sobrinho-Simões
Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.
Cancer letters 2005;230(1):149-50.
2005: Ginesa García-Rostán; Angela M Costa; Isabel Pereira-Castro; Giuliana Salvatore; Radhames Hernandez; Mario J A Hermsem; Agustin Herrero; Alfredo Fusco; José Cameselle-Teijeiro; Massimo Santoro
Mutation of the PIK3CA gene in anaplastic thyroid cancer.
Cancer research 2005;65(22):10199-207.
2005: Valentina Guarino; Pinuccia Faviana; Giuliana Salvatore; Maria Domenica Castellone; Anna Maria Cirafici; Valentina De Falco; Angela Celetti; Riccardo Giannini; Fulvio Basolo; Rosa Marina Melillo; Massimo Santoro
Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness.
The Journal of clinical endocrinology and metabolism 2005;90(9):5270-8.
2005: Teresa Guida; Giuliana Salvatore; Pinuccia Faviana; Riccardo Giannini; Ginesa Garcia-Rostan; Livia Provitera; Fulvio Basolo; Alfredo Fusco; Francesca Carlomagno; Massimo Santoro
Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2005;90(8):4703-9.
2005: Rosa Marina Melillo; Maria Domenica Castellone; Valentina Guarino; Valentina De Falco; Anna Maria Cirafici; Giuliana Salvatore; Fiorina Caiazzo; Fulvio Basolo; Riccardo Giannini; Mogens Kruhoffer; Torben F Orntoft; Alfredo Fusco; Massimo Santoro
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells.
The Journal of clinical investigation 2005;115(4):1068-81.
2005: Giuliana Salvatore; Gennaro Chiappetta; Yuri E Nikiforov; Myriam Decaussin-Petrucci; Alfredo Fusco; J Aidan Carney; Massimo Santoro
Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations.
European journal of cancer (Oxford, England : 1990) 2005;41(5):816-21.
2004: Giuliana Salvatore; Riccardo Giannini; Pinuccia Faviana; Alessia Caleo; Ilenia Migliaccio; James A Fagin; Yuri E Nikiforov; Giancarlo Troncone; Lucio Palombini; Fulvio Basolo; Massimo Santoro
Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2004;89(10):5175-80.
2004: Kristian Unger; Horst Zitzelsberger; Giuliana Salvatore; Massimo Santoro; Tetyana I Bogdanova; Herbert Braselmann; Peter Kastner; Lyudmilla Zurnadzhy; Nikolay Tronko; Peter Hutzler; Gerry Thomas
Heterogeneity in the distribution of RET/PTC rearrangements within individual post-Chernobyl papillary thyroid carcinomas.
The Journal of clinical endocrinology and metabolism 2004;89(9):4272-9.
2004: Jorge Lima; Vítor Trovisco; Paula Soares; Valdemar Maximo; João Magalhães; Giuliana Salvatore; Massimo Santoro; Tetyana I Bogdanova; Mykola D Tronko; Alexander Abrosimov; Steve Jeremiah; Gerry Thomas; Dillwyn Williams; Manuel Sobrinho-Simões
BRAF mutations are not a major event in post-Chernobyl childhood thyroid carcinomas.
The Journal of clinical endocrinology and metabolism 2004;89(9):4267-71.
2004: Marina N Nikiforova; Raffaele Ciampi; Giuliana Salvatore; Massimo Santoro; Manoj Gandhi; Jeffrey A Knauf; Gerry A Thomas; Steve Jeremiah; Tetyana I Bogdanova; Mykola D Tronko; James A Fagin; Yuri E Nikiforov
Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.
Cancer letters 2004;209(1):1-6.
2003: Marina N Nikiforova; Edna T Kimura; Manoj Gandhi; Paul Williams Biddinger; Jeffrey A Knauf; Fulvio Basolo; Zhaowen Zhu; Riccardo Giannini; Giuliana Salvatore; Alfredo Fusco; Massimo Santoro; James A Fagin; Yuri E Nikiforov
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas.
The Journal of clinical endocrinology and metabolism 2003;88(11):5399-404.
2003: Satoshi Nagata; Giuliana Salvatore; Ira Pastan
DNA immunization followed by a single boost with cells: a protein-free immunization protocol for production of monoclonal antibodies against the native form of membrane proteins.
Journal of immunological methods 2003;280(1-2):59-72.
2002: Giuliana Salvatore; Satoshi Nagata; Marc Billaud; Massimo Santoro; Giancarlo Vecchio; Ira Pastan
Generation and characterization of novel monoclonal antibodies to the Ret receptor tyrosine kinase.
Biochemical and biophysical research communications 2002;294(4):813-7.
2002: Giuliana Salvatore; Richard Beers; Inger Margulies; Robert J Kreitman; Ira Pastan
Improved cytotoxic activity toward cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):995-1002.
2002: Gustavo Baldassarre; Paola Bruni; Angelo Boccia; Giuliana Salvatore; Rosa Marina Melillo; Maria Letizia Motti; Maria Napolitano; Barbara Belletti; Alfredo Fusco; Massimo Santoro; Giuseppe Viglietto
Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27(kip1).
Oncogene 2002;21(11):1739-49.
2002: Tapan K Bera; Rangan Maitra; Carlo Iavarone; Giuliana Salvatore; Vasantha Kumar; James J Vincent; Bangalore K Sathyanarayana; Paul H Duray; B K Lee; Ira Pastan
PATE, a gene expressed in prostate cancer, normal prostate, and testis, identified by a functional genomic approach.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3058-63.
2002: Fulvio Basolo; Riccardo Giannini; Carmen Monaco; Rosa Marina Melillo; Francesca Carlomagno; Martina Pancrazi; Giuliana Salvatore; Gennaro Chiappetta; Furio Pacini; Rossella Elisei; Paolo Miccoli; Aldo Pinchera; Alfredo Fusco; Massimo Santoro
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma.
The American journal of pathology 2002;160(1):247-54.
2000: Domenico Salvatore; Maria Vittoria Barone; Giuliana Salvatore; Rosa Marina Melillo; Gennaro Chiappetta; Alba Mineo; Gianfranco Fenzi; Giancarlo Vecchio; Alfredo Fusco; Massimo Santoro
Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins.
The Journal of clinical endocrinology and metabolism 2000;85(10):3898-907.
2000: Giuseppe Viglietto; S Dolci; Paola Bruni; Gustavo Baldassarre; Lorenzo Chiariotti; Rosa Marina Melillo; Giuliana Salvatore; Gennaro Chiappetta; F Sferratore; Alfredo Fusco; Massimo Santoro
Glial cell line-derived neutrotrophic factor and neurturin can act as paracrine growth factors stimulating DNA synthesis of Ret-expressing spermatogonia.
International journal of oncology 2000;16(4):689-94.
2000: Riccardo Giannini; Giuliana Salvatore; Carmen Monaco; F Sferratore; Luca Pollina; Furio Pacini; Fulvio Basolo; Alfredo Fusco; Massimo Santoro
Identification of a novel subtype of H4-RET rearrangement in a thyroid papillary carcinoma and lymph node metastasis.
International journal of oncology 2000;16(3):485-9.
1999: Gerry A Thomas; H Bunnell; H A Cook; E Dillwyn Williams; A Nerovnya; ED Cherstvoy; Nikolay Tronko; Tetyana I Bogdanova; Gennaro Chiappetta; Giuseppe Viglietto; Francesca Pentimalli; Giuliana Salvatore; Alfredo Fusco; Massimo Santoro; Giancarlo Vecchio
High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant.
The Journal of clinical endocrinology and metabolism 1999;84(11):4232-8.
1999: Barbara Belletti; P Ferraro; Claudio Arra; Gustavo Baldassarre; Paola Bruni; stefania staibano; G De Rosa; Giuliana Salvatore; Alfredo Fusco; M Graziella Persico; Giuseppe Viglietto
Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene.
Oncogene 1999;18(34):4860-9.
1999: Massimo Santoro; Rosa Marina Melillo; Francesca Carlomagno; Roberta Visconti; Gabriella De Vita; Giuliana Salvatore; Alfredo Fusco; Giancarlo Vecchio
Different mutations of the RET gene cause different human tumoral diseases.
Biochimie 1999;81(4):397-402.
1999: Luca Cindolo; G Benvenuto; Paola Salvatore; Raffaela Pero; Giuliana Salvatore; Vincenzo Mirone; Domenico Prezioso; Vincenzo Altieri; Carmelo B Bruni; Lorenzo Chiariotti
galectin-1 and galectin-3 expression in human bladder transitional-cell carcinomas.
International journal of cancer. Journal international du cancer 1999;84(1):39-43.
1998: Francesca Carlomagno; Rosa Marina Melillo; Roberta Visconti; Giuliana Salvatore; Gabriella De Vita; Giovanni Lupoli; Yanbin Yu; Shuqian Jing; Giancarlo Vecchio; Alfredo Fusco; Massimo Santoro
Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.
Endocrinology 1998;139(8):3613-9.
1998: Massimo Santoro; Rosa Marina Melillo; Francesca Carlomagno; Roberta Visconti; Gabriella De Vita; Giuliana Salvatore; Giovanni Lupoli; Alfredo Fusco; Giancarlo Vecchio
Molecular biology of the MEN2 gene.
Journal of internal medicine 1998;243(6):505-8.
1998: Giovanni Tallini; M Santoro; M Helie; Francesca Carlomagno; Giuliana Salvatore; Gennaro Chiappetta; Maria Luisa Carcangiu; A Fusco
RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):287-94.
1997: Gustavo Baldassarre; A Romano; F Armenante; M Rambaldi; I Paoletti; C Sandomenico; Stefano Pepe; stefania staibano; Giuliana Salvatore; Gaetano De Rosa; M Graziella Persico; Giuseppe Viglietto
Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1.
Oncogene 1997;15(8):927-36.
1997: Anna Maria Cirafici; Giuliana Salvatore; Gabriella De Vita; Francesca Carlomagno; N A Dathan; Roberta Visconti; Rosa Marina Melillo; Alfredo Fusco; Massimo Santoro
Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential.
Endocrinology 1997;138(4):1450-5.
1997: Francesca Carlomagno; Giuliana Salvatore; Anna Maria Cirafici; Gabriella De Vita; Rosa Marina Melillo; Vittorio de Franciscis; Marc Billaud; Alfredo Fusco; Massimo Santoro
The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype.
Cancer research 1997;57(3):391-5.