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Daniela Salvemini

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TOP 3
T Doyle; E Esposito; L Bryant; Salvatore Cuzzocrea; Daniela Salvemini
NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice.
Daniela Salvemini; Sangwon F Kim; Vincenzo Mollace
Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications.
Daniela Salvemini; Timothy Doyle; Michaela Kress; Grant Nicol
Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain.

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All Publications

2013: T Doyle; E Esposito; L Bryant; Salvatore Cuzzocrea; Daniela Salvemini
NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice.
Neuroscience 2013;241():1-9.
2013: Daniela Salvemini; Sangwon F Kim; Vincenzo Mollace
Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications.
American journal of physiology. Regulatory, integrative and comparative physiology 2013;304(7):R473-87.
2013: Daniela Salvemini; Timothy Doyle; Michaela Kress; Grant Nicol
Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain.
Trends in pharmacological sciences 2013;34(2):110-8.
2013: Amanda Finley; Roger Sabbadini; Zhoumou Chen; Salvatore Cuzzocrea; Emanuela Esposito; Daniela Salvemini
Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism.
PloS one 2013;8(1):e55255.
2012: Timothy Doyle; Emanuela Esposito; Andrew Kamadulski; Carolina Muscoli; William L Neumann; Smita Rausaria; Jan Ryerse; Leesa Bryant; Zhoumou Chen; Salvatore Cuzzocrea; Concetta Dagostino; Daniela Salvemini
Targeting the overproduction of peroxynitrite for the prevention and reversal of paclitaxel-induced neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(18):6149-60.
2012: Zhoumou Chen; Tim Doyle; Kenneth Alan Jacobson; Kali Janes; Leesa Bryant; Collin Chen; Dilip K Tosh; Daniela Salvemini
Controlling murine and rat chronic pain through A3 adenosine receptor activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(5):1855-65.
2012: Kali Janes; William L Neumann; Daniela Salvemini
Anti-superoxide and anti-peroxynitrite strategies in pain suppression.
Biochimica et biophysica acta 2012;1822(5):815-21.
2011: Daniela Salvemini; Timothy Doyle; Joshua W Little; William L Neumann
Roles of reactive oxygen and nitrogen species in pain.
Free radical biology & medicine 2011;51(5):951-66.
2011: Tim Doyle; Lina M Obeid; Zhoumou Chen; Daniela Salvemini
Sphingosine-1-phosphate acting via the S1P₁ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia.
Neuroscience letters 2011;499(1):4-8.
2011: Wolfram E Samlowski; Muralidhar Kondapaneni; Shweta Tharkar; John R McGregor; Victor E Laubach; Daniela Salvemini
Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(5):419-27.
2011: Artak G Tovmasyan; Zrinka Rajic; Ivan Spasojevic; Julio S Reboucas; Xin Chen; Daniela Salvemini; Huaxin Sheng; David S Warner; Ludmil Benov; Ines Batinic-Haberle
Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.
Dalton transactions (Cambridge, England : 2003) 2011;40(16):4111-21.
2011: Tim Doyle; Amanda Finley; Zhoumou Chen; Daniela Salvemini
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.
Pain 2011;152(3):643-8.
2010: Carolina Muscoli; Tim Doyle; Concetta Dagostino; Leesa Bryant; Zhoumou Chen; Linda R Watkins; Jan Ryerse; Erhard Bieberich; William Neumman; Daniela Salvemini
Counter-regulation of opioid analgesia by glial-derived bioactive sphingolipids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(46):15400-8.
2010: Tim Doyle; Leesa Bryant; Carolina Muscoli; Salvatore Cuzzocrea; Emanuela Esposito; Zhoumou Chen; Daniela Salvemini
Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance.
Neuroscience letters 2010;483(2):85-9.
2010: Daniela Salvemini
Searching for new strategies for the pharmacological treatment of chronic pain.
Missouri medicine 2010;107(4):262-4.
2010: Daniela Salvemini; William Neumann
Targeting peroxynitrite driven nitroxidative stress with synzymes: A novel therapeutic approach in chronic pain management.
Life sciences 2010;86(15-16):604-14.
2010: Zhoumou Chen; Carolina Muscoli; Tim Doyle; L Bryant; Salvatore Cuzzocrea; Vincenzo Mollace; Rosanna Mastroianni; Emanuela Masini; Daniela Salvemini
NMDA-receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing.
Pain 2010;149(1):100-6.
2009: T Doyle; L Bryant; I Batinic-Haberle; J Little; Salvatore Cuzzocrea; Emanuela Masini; I Spasojevic; Daniela Salvemini
Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.
Neuroscience 2009;164(2):702-10.
2009: Leesa Bryant; Tim Doyle; Zhoumo Chen; Salvatore Cuzzocrea; Emanuela Masini; M Cristina Vinci; Emanuela Esposito; Emanuela Mazzon; Daniela Nicoleta Petrusca; Irina Petrache; Daniela Salvemini
Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance.
Neuroscience letters 2009;463(1):49-53.
2009: Ivan Kos; Júlio S Rebouças; Gilson DeFreitas-Silva; Daniela Salvemini; Zeljko Vujaskovic; Mark Dewhirst; Ivan Spasojević; Ines Batinić-Haberle
Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.
Free radical biology & medicine 2009;47(1):72-8.
2009: Salvatore Cuzzocrea; Hans-Peter Deigner; Tiziana Genovese; Emanuela Mazzon; Emanuela Esposito; Concetta Crisafulli; Rosanna Di Paola; Placido Bramanti; George Matuschak; Daniela Salvemini
Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury.
Shock (Augusta, Ga.) 2009;31(6):634-44.
2009: Daniela Salvemini
Peroxynitrite and opiate antinociceptive tolerance: a painful reality.
Archives of biochemistry and biophysics 2009;484(2):238-44.
2009: Emanuela Masini; E Ragazzo; Maria Cristina Vinci; Silvia Nistri; L Cinci; Rosanna Mastroianni; Robin Thurmond; Daniela Salvemini
A selective H4R antagonist prevents antigen-induced asthma-like reaction and airway inflammation in guinea pigs.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2009;58 Suppl 1():9-10.
2009: Michael M Ndengele; Salvatore Cuzzocrea; Emanuela Masini; M Cristina Vinci; Emanuela Esposito; Carolina Muscoli; Daniela Nicoleta Petrusca; Vincenzo Mollace; Emanuela Mazzon; Dechun Li; Irina Petrache; George M Matuschak; Daniela Salvemini
Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation.
The Journal of pharmacology and experimental therapeutics 2009;329(1):64-75.
2009: Salvatore Cuzzocrea; Tiziana Genovese; Emanuela Mazzon; Emanuela Esposito; Concetta Crisafulli; Rosanna Di Paola; Placido Bramanti; Daniela Salvemini
Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice.
Shock (Augusta, Ga.) 2009;31(2):170-7.
2009: Ines Batinić-Haberle; Salvatore Cuzzocrea; Júlio S Rebouças; Gerardo Ferrer-Sueta; Emanuela Mazzon; Rosanna Di Paola; Rafael Radi; Ivan Spasojević; Ludmil Benov; Daniela Salvemini
Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.
Free radical biology & medicine 2009;46(2):192-201.
2009: Ines Batinić-Haberle; Michael M Ndengele; Salvatore Cuzzocrea; Júlio S Rebouças; Ivan Spasojević; Daniela Salvemini
Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.
Free radical biology & medicine 2009;46(2):212-9.
2008: Salvatore Cuzzocrea; Rosanna Di Paola; Tiziana Genovese; Emanuela Mazzon; Emanuela Esposito; Concetta Crisafulli; Placido Bramanti; Daniela Salvemini
Anti-inflammatory and anti-apoptotic effects of fumonisin B1, an inhibitor of ceramide synthase, in a rodent model of splanchnic ischemia and reperfusion injury.
The Journal of pharmacology and experimental therapeutics 2008;327(1):45-57.
2008: Michael M Ndengele; Salvatore Cuzzocrea; Emanuela Esposito; Emanuela Mazzon; Rosanna Di Paola; George M Matuschak; Daniela Salvemini
Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3154-64.
2008: Muralidhar Kondapaneni; John R McGregor; Daniela Salvemini; Victor E Laubach; Wolfram E Samlowski
Inducible nitric oxide synthase (iNOS) is not required for IL-2-induced hypotension and vascular leak syndrome in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(4):325-33.
2008: Emanuela Masini; Lucia Giannini; Silvia Nistri; Lorenzo Cinci; Rosanna Mastroianni; Wei Xu; Suzy A A Comhair; Dechun Li; Salvatore Cuzzocrea; George M Matuschak; Daniela Salvemini
Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation.
The Journal of pharmacology and experimental therapeutics 2008;324(2):548-57.
2007: Carolina Muscoli; Salvatore Cuzzocrea; Michael M Ndengele; Vincenzo Mollace; Frank Porreca; Francesca Fabrizi; Emanuela Esposito; Emanuela Masini; George M Matuschak; Daniela Salvemini
Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice.
The Journal of clinical investigation 2007;117(11):3530-9.
2006: Daniela Salvemini; Timothy M Doyle; S Cuzzocrea
Superoxide, peroxynitrite and oxidative/nitrative stress in inflammation.
Biochemical Society transactions 2006;34(Pt 5):965-70.
2006: Salvatore Cuzzocrea; Emanuela Mazzon; Rosanna Di Paola; Emanuela Esposito; Heather Macarthur; George M Matuschak; Daniela Salvemini
A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock.
The Journal of pharmacology and experimental therapeutics 2006;319(1):73-81.
2005: Salvatore Cuzzocrea; Emanuela Mazzon; Rosanna Di Paola; Tiziana Genovese; Carmelo Muià; Achille P Caputi; Daniela Salvemini
Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance.
Arthritis and rheumatism 2005;52(12):3755-60.
2005: Emanuela Masini; Daniele Bani; Alfredo Vannacci; Simone Pierpaoli; Pier Francesco Mannaioni; Suzy A A Comhair; Weiling Xu; Carolina Muscoli; Serpil C Erzurum; Daniela Salvemini
Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic.
Free radical biology & medicine 2005;39(4):520-31.
2005: Salvatore Cuzzocrea; Emanuela Mazzon; Rosanna Di Paola; Tiziana Genovese; Carmelo Muià; Achille P Caputi; Daniela Salvemini
Effects of combination M40403 and dexamethasone therapy on joint disease in a rat model of collagen-induced arthritis.
Arthritis and rheumatism 2005;52(6):1929-40.
2005: Vincenzo Mollace; Carolina Muscoli; Emanuela Masini; Salvatore Cuzzocrea; Daniela Salvemini
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors.
Pharmacological reviews 2005;57(2):217-52.
2005: Michael M Ndengele; Carolina Muscoli; Zhi Qiang Wang; Timothy M Doyle; George M Matuschak; Daniela Salvemini
Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages.
Shock (Augusta, Ga.) 2005;23(2):186-93.
2004: Carolina Muscoli; Iolanda Sacco; Wanessa Alecce; Ernesto Palma; Robert Nisticò; Nicola Costa; Fabrizio Clementi; Domenicantonio Rotiroti; Francesco Romeo; Daniela Salvemini; Jawahar L Mehta; Vincenzo Mollace
The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1.
The Journal of pharmacology and experimental therapeutics 2004;311(1):44-50.
2004: Xizhong Cui; Chantal Parent; Heather Macarthur; Scott D Ochs; Eric Gerstenberg; Steve Solomon; Yvonne Fitz; Robert L Danner; Steven M Banks; Charles Natanson; Daniela Salvemini; Peter Q Eichacker
Severity of sepsis alters the effects of superoxide anion inhibition in a rat sepsis model.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;97(4):1349-57.
2004: Carolina Muscoli; Vincenzo Mollace; James Wheatley; Emanuela Masini; Michael M Ndengele; Zhi-Qiang Wang; Daniela Salvemini
Superoxide-mediated nitration of spinal manganese superoxide dismutase: a novel pathway in N-methyl-D-aspartate-mediated hyperalgesia.
Pain 2004;111(1-2):96-103.
2004: Salvatore Cuzzocrea; Tiziana Genovese; Emanuela Mazzon; Rosanna Di Paola; Carmelo Muià; Domenico Britti; Daniela Salvemini
Reduction in the development of cerulein-induced acute pancreatitis by treatment with M40401, a new selective superoxide dismutase mimetic.
Shock (Augusta, Ga.) 2004;22(3):254-61.
2004: Salvatore Cuzzocrea; Barbara Pisano; Laura Dugo; ANGELA IANARO; Michael M Ndengele; Daniela Salvemini
Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation.
Antioxidants & redox signaling 2004;6(4):699-704.
2004: Zhi-Qiang Wang; Frank Porreca; Salvatore Cuzzocrea; Karen Galen; Richard Lightfoot; Emanuela Masini; Carolina Muscoli; Vincenzo Mollace; Michael M Ndengele; Harry Ischiropoulos; Daniela Salvemini
A newly identified role for superoxide in inflammatory pain.
The Journal of pharmacology and experimental therapeutics 2004;309(3):869-78.
2004: Salvatore Cuzzocrea; Christoph Thiemermann; Daniela Salvemini
Potential therapeutic effect of antioxidant therapy in shock and inflammation.
Current medicinal chemistry 2004;11(9):1147-62.
2004: Salvatore Cuzzocrea; Emanuela Mazzon; Laura Dugo; Rosanna Di Paola; Achille P Caputi; Daniela Salvemini
Superoxide: a key player in hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):94-101.
2004: Salvatore Cuzzocrea; Emanuela Mazzon; Rosanna Di Paola; Tiziana Genovese; Ivana Serraino; Laura Dugo; Elisabetta Cuzzocrea; Francesco Fulia; Achille P Caputi; Daniela Salvemini
Protective effects of M40401, a selective superoxide dismutase mimetic, on zymosan-induced nonseptic shock.
Critical care medicine 2004;32(1):157-67.
2003: Carolina Muscoli; Salvatore Cuzzocrea; Dennis P Riley; Jay L Zweier; Christoph Thiemermann; Zhi-Qiang Wang; Daniela Salvemini
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies.
British journal of pharmacology 2003;140(3):445-60.
2003: Vincenzo Mollace; Michelangelo Iannone; Carolina Muscoli; Ernesto Palma; Teresa Granato; Andrea Modesti; Robert Nisticò; Domenicantonio Rotiroti; Daniela Salvemini
The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils.
BMC pharmacology 2003;3():8.
2003: Wolfram E Samlowski; Ryan Petersen; Salvatore Cuzzocrea; Heather Macarthur; Damali Burton; John R McGregor; Daniela Salvemini
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects.
Nature medicine 2003;9(6):750-5.
2003: Cosimo Marzocca; Alfredo Vannacci; Salvatore Cuzzocrea; Daniela Salvemini; Pier Francesco Mannaioni; Emanuela Masini
Effects of the SOD mimetic, M40403, on prostaglandin production in an in vivo model of ischemia and reperfusion in rat heart.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52 Suppl 1():S23-4.
2003: Vincenzo Mollace; Michelangelo Iannone; Carolina Muscoli; Ernesto Palma; Teresa Granato; Vincenzo Rispoli; Robert Nisticò; Domenicantonio Rotiroti; Daniela Salvemini
The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic.
Neuroscience letters 2003;335(3):163-6.
2003: Heather Macarthur; Daniel M Couri; Gerald H Wilken; Thomas C Westfall; Andrew J Lechner; George M Matuschak; Zhoumou Chen; Daniela Salvemini
Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines.
Critical care medicine 2003;31(1):237-45.
2002: Carolina Muscoli; Daniela Salvemini; Donatella Paolino; Michelangelo Iannone; Ernesto Palma; Antonio Cufari; Domenicantonio Rotiroti; Carlo Federico Perno; Stefano Aquaro; Vincenzo Mollace
Peroxynitrite decomposition catalyst prevents apoptotic cell death in a human astrocytoma cell line incubated with supernatants of HIV-infected macrophages.
BMC neuroscience 2002;3():13.
2002: Salvatore Cuzzocrea; Emanuela Mazzon; Laura Dugo; Ivana Serraino; Rosanna Di Paola; Domenico Britti; Angela De Sarro; Simone Pierpaoli; Achille Caputi; Emanuela Masini; Daniela Salvemini
A role for superoxide in gentamicin-mediated nephropathy in rats.
European journal of pharmacology 2002;450(1):67-76.
2002: Emanuela Masini; Salvatore Cuzzocrea; Emanuela Mazzon; Cosimo Marzocca; Pier Francesco Mannaioni; Daniela Salvemini
Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo.
British journal of pharmacology 2002;136(6):905-17.
2002: Daniela Salvemini; Dennis P Riley; Salvatore Cuzzocrea
SOD mimetics are coming of age.
Nature reviews. Drug discovery 2002;1(5):367-74.
2002: Vincenzo Mollace; Carolina Muscoli; Michelangelo Iannone; Ernesto Palma; Domenicantonio Rotiroti; Francesco Romeo; Robert Nisticò; Daniela Salvemini
Dexamethasone inhibits the inducible bioconversion of glyceryl trinitrate to nitric oxide.
Journal of cardiovascular pharmacology 2002;39(4):544-51.
2002: Daniela Salvemini; Carolina Muscoli; Dennis P Riley; Salvatore Cuzzocrea
Superoxide dismutase mimetics.
Pulmonary pharmacology & therapeutics 2002;15(5):439-47.
2002: Vincenzo Mollace; Daniela Salvemini; Dennis P Riley; Carolina Muscoli; Michelangelo Iannone; Teresa Granato; Laura Masuelli; Andrea Modesti; Domenicantonio Rotiroti; Robert Nisticó; Ada Bertoli; Carlo Federico Perno; Stefano Aquaro
The contribution of oxidative stress in apoptosis of human-cultured astroglial cells induced by supernatants of HIV-1-infected macrophages.
Journal of leukocyte biology 2002;71(1):65-72.
2001: Daniela Salvemini; E Mazzon; Laura Dugo; Ivana Serraino; A De Sarro; A P Caputi; S Cuzzocrea
Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic.
Arthritis and rheumatism 2001;44(12):2909-21.
2001: Salvatore Cuzzocrea; Emanuela Mazzon; Laura Dugo; Achille P Caputi; Dennis P Riley; Daniela Salvemini
Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis.
European journal of pharmacology 2001;432(1):79-89.
2001: Vincenzo Mollace; H S Nottet; P Clayette; M C Turco; Carolina Muscoli; Daniela Salvemini; Carlo Federico Perno
Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants.
Trends in neurosciences 2001;24(7):411-6.
2001: Salvatore Cuzzocrea; Dennis P Riley; Achille P Caputi; Daniela Salvemini
Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury.
Pharmacological reviews 2001;53(1):135-59.
2001: Daniela Salvemini; Emanuela Mazzon; Laura Dugo; Dennis P Riley; Ivana Serraino; Achille P Caputi; Salvatore Cuzzocrea
Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403.
British journal of pharmacology 2001;132(4):815-27.
2001: Salvatore Cuzzocrea; Emanuela Mazzon; Laura Dugo; Achille P Caputi; K Aston; Dennis P Riley; Daniela Salvemini
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion.
British journal of pharmacology 2001;132(1):19-29.
2000: Heather Macarthur; Thomas C Westfall; Dennis P Riley; TP Misko; Daniela Salvemini
Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9753-8.
2000: Anne H Cross; M San; MK Stern; RM Keeling; Daniela Salvemini; TP Misko
A catalyst of peroxynitrite decomposition inhibits murine experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2000;107(1):21-8.
2000: S Cuzzocrea; TP Misko; G Costantino; E Mazzon; A Micali; A P Caputi; Heather Macarthur; Daniela Salvemini
Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(9):1061-72.
1999: Emanuela Masini; Daniela Salvemini; JF Ndisang; P Gai; LA Berni; M Moncini; S Bianchi; Pier Francesco Mannaioni
Cardioprotective activity of endogenous and exogenous nitric oxide on ischaemia reperfusion injury in isolated guinea pig hearts.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(11):561-8.
1999: Daniela Salvemini; Zhi-Qiang Wang; Jay L Zweier; A Samouilov; Heather Macarthur; TP Misko; Mark G Currie; Salvatore Cuzzocrea; J A Sikorski; Dennis P Riley
A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats.
Science (New York, N.Y.) 1999;286(5438):304-6.
1999: Daniela Salvemini; Dennis P Riley; P J Lennon; Zhi-Qiang Wang; Mark G Currie; Heather Macarthur; TP Misko
Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage.
British journal of pharmacology 1999;127(3):685-92.
1998: TP Misko; M K Highkin; A W Veenhuizen; Pamela T Manning; MK Stern; Mark G Currie; Daniela Salvemini
Characterization of the cytoprotective action of peroxynitrite decomposition catalysts.
The Journal of biological chemistry 1998;273(25):15646-53.
1998: Daniela Salvemini; M P Jensen; Dennis P Riley; TP Misko
Therapeutic manipulations of peroxynitrite.
Drug news & perspectives 1998;11(4):204-14.
1998: Daniela Salvemini; Z Q Wang; MK Stern; Mark G Currie; TP Misko
Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2659-63.
1998: Daniela Salvemini; M H Marino
Inducible nitric oxide synthase and inflammation.
Expert opinion on investigational drugs 1998;7(1):65-75.
1996: Daniela Salvemini; Z Q Wang; P S Wyatt; D M Bourdon; M H Marino; Pamela T Manning; M G Currie
Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation.
British journal of pharmacology 1996;118(4):829-38.
1996: Daniela Salvemini; M G Currie; Vincenzo Mollace
Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators.
The Journal of clinical investigation 1996;97(11):2562-8.
1996: Daniela Salvemini; Z Q Wang; D M Bourdon; MK Stern; M G Currie; Pamela T Manning
Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema.
European journal of pharmacology 1996;303(3):217-20.
1996: Karen Seibert; Jaime L Masferrer; P Needleman; Daniela Salvemini
Pharmacological manipulation of cyclo-oxygenase-2 in the inflamed hydronephrotic kidney.
British journal of pharmacology 1996;117(6):1016-20.
1996: Emanuela Masini; Daniela Salvemini; L Mugnai; MG Bello; Daniele Bani; Pier Francesco Mannaioni
The effect of relaxin on myocardial ischaemia-reperfusion injury and histamine release in vitro and in vivo.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1996;45 Suppl 1():S27-8.
1996: Daniela Salvemini; Jaime L Masferrer
Interactions of nitric oxide with cyclooxygenase: in vitro, ex vivo, and in vivo studies.
Methods in enzymology 1996;269():12-25.
1995: Daniela Salvemini; Pamela T Manning; Ben S Zweifel; Karen Seibert; J Connor; M G Currie; P Needleman; Jaime L Masferrer
Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors.
The Journal of clinical investigation 1995;96(1):301-8.
1995: Daniela Salvemini; Steven L Settle; Jaime L Masferrer; Karen Seibert; M G Currie; P Needleman
Regulation of prostaglandin production by nitric oxide; an in vivo analysis.
British journal of pharmacology 1995;114(6):1171-8.
1995: Peter C Isakson; Karen Seibert; Jaime L Masferrer; Daniela Salvemini; L Lee; P Needleman
Discovery of a better aspirin.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():49-54.
1995: Daniela Salvemini; Karen Seibert; Jaime L Masferrer; Steven L Settle; TP Misko; M G Currie; P Needleman
Nitric oxide and the cyclooxygenase pathway.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():491-3.
1994: A Pistelli; Vincenzo Mollace; G Nistico; Daniela Salvemini; JR Vane
Nitroblue tetrazolium inhibits oxidation of glyceryl trinitrate to nitric oxide in bovine aortic smooth muscle cells.
Biochemical pharmacology 1994;47(10):1737-42.
1994: Daniela Salvemini; Karen Seibert; Jaime L Masferrer; TP Misko; M G Currie; P Needleman
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation.
The Journal of clinical investigation 1994;93(5):1940-7.
1993: Daniela Salvemini; A Pistelli; E Anggard
Vascular and anti-platelet actions of 1,2- and 1,3-glyceryl dinitrate.
British journal of pharmacology 1993;110(3):937-42.
1993: TP Misko; R J Schilling; Daniela Salvemini; William M Moore; M G Currie
A fluorometric assay for the measurement of nitrite in biological samples.
Analytical biochemistry 1993;214(1):11-6.
1993: Daniela Salvemini; TP Misko; Jaime L Masferrer; Karen Seibert; M G Currie; P Needleman
Nitric oxide activates cyclooxygenase enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7240-4.
1993: Daniela Salvemini; A Pistelli; Vincenzo Mollace
Release of nitric oxide from glyceryl trinitrate by captopril but not enalaprilat: in vitro and in vivo studies.
British journal of pharmacology 1993;109(2):430-6.
1993: Daniela Salvemini; R Botting
Modulation of platelet function by free radicals and free-radical scavengers.
Trends in pharmacological sciences 1993;14(2):36-42.
1993: Daniela Salvemini; A Pistelli; JR Vane
Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells.
British journal of pharmacology 1993;108(1):162-9.
1992: Daniela Salvemini; Vincenzo Mollace; A Pistelli; E Anggård; JR Vane
Cultured astrocytoma cells generate a nitric oxide-like factor from endogenous L-arginine and glyceryl trinitrate: effect of E. coli lipopolysaccharide.
British journal of pharmacology 1992;106(4):931-6.
1992: Ryszard J Gryglewski; A Zembowicz; Daniela Salvemini; G W Taylor; JR Vane
Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin.
British journal of pharmacology 1992;106(4):838-45.
1992: Daniela Salvemini; A Pistelli; Vincenzo Mollace; E Anggård; JR Vane
The metabolism of glyceryl trinitrate to nitric oxide in the macrophage cell line J774 and its induction by Escherichia coli lipopolysaccharide.
Biochemical pharmacology 1992;44(1):17-24.
1992: Daniela Salvemini; Vincenzo Mollace; A Pistelli; E Anggard; JR Vane
Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(3):982-6.
1991: Vincenzo Mollace; Daniela Salvemini; JR Vane
Studies on the importance of the proposed release of nitric oxide from platelets.
Thrombosis research 1991;64(5):533-42.
1991: Vincenzo Mollace; Daniela Salvemini; E Anggard; JR Vane
Nitric oxide from vascular smooth muscle cells: regulation of platelet reactivity and smooth muscle cell guanylate cyclase.
British journal of pharmacology 1991;104(3):633-8.
1991: Vincenzo Mollace; Daniela Salvemini; William C Sessa; JR Vane
Inhibition of human platelet aggregation by endothelium-derived relaxing factor, sodium nitroprusside or iloprost is potentiated by captopril and reduced thiols.
The Journal of pharmacology and experimental therapeutics 1991;258(3):820-3.
1991: E Masini; P F Mannaioni; A Pistelli; Daniela Salvemini; JR Vane
Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats.
Biochemical and biophysical research communications 1991;177(3):1178-82.
1991: Daniela Salvemini; W Radziszewski; Vincenzo Mollace; A Moore; D Willoughby; JR Vane
Diphenylene iodonium, an inhibitor of free radical formation, inhibits platelet aggregation.
European journal of pharmacology 1991;199(1):15-8.
1991: Emanuela Masini; Daniela Salvemini; A Pistelli; Pier Francesco Mannaioni; JR Vane
Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine.
Agents and actions 1991;33(1-2):61-3.
1991: Daniela Salvemini; G de Nucci; JR Vane
Superoxide dismutase cooperates with prostacyclin to inhibit platelet aggregation: a comparative study in washed platelets and platelet rich plasma.
Thrombosis and haemostasis 1991;65(4):421-4.
1991: Pier Francesco Mannaioni; Emanuela Masini; A Pistelli; Daniela Salvemini; JR Vane
Mast cells as a source of superoxide anions and nitric oxide-like factor: relevance to histamine release.
International journal of tissue reactions 1991;13(6):271-8.
1991: Pier Francesco Mannaioni; Emanuela Masini; A Pistelli; Daniela Salvemini; JR Vane
Rat mast cells inhibit platelet aggregation by releasing a nitric oxide-like factor: influence of histamine release.
Agents and actions. Supplements 1991;33():423-8.
1990: Daniela Salvemini; W Radziszewski; R Korbut; JR Vane
The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO-donors.
British journal of pharmacology 1990;101(4):991-5.
1990: Vincenzo Mollace; Daniela Salvemini; E Anggård; JR Vane
Cultured astrocytoma cells inhibit platelet aggregation by releasing a nitric oxide-like factor.
Biochemical and biophysical research communications 1990;172(2):564-9.
1990: Daniela Salvemini; E Masini; E Anggard; P F Mannaioni; JR Vane
Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: stimulation of guanylate cyclase and inhibition of platelet aggregation.
Biochemical and biophysical research communications 1990;169(2):596-601.
1990: Daniela Salvemini; R Korbut; E Anggård; JR Vane
Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2593-7.
1989: Daniela Salvemini; R Korbut; E Anggård; JR Vane
Lipopolysaccharide increases release of a nitric oxide-like factor from endothelial cells.
European journal of pharmacology 1989;171(1):135-6.
1989: Daniela Salvemini; G de Nucci; J M Sneddon; JR Vane
Superoxide anions enhance platelet adhesion and aggregation.
British journal of pharmacology 1989;97(4):1145-50.
1989: Daniela Salvemini; G de Nucci; R J Gryglewski; JR Vane
Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6328-32.