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Ali Samii

Research Profile

Disorders

Parkinson's Disease

Physiology

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Taryn O Hall; Kathleen F Kerr; Ignacio F Mata; John W Roberts; Ali Samii; Katherine W Snapinn; Jia Y Wan; Cyrus Zabetian; Pinky Agarwal; Karen L Edwards
Risk prediction for complex diseases: application to Parkinson disease.
Ignacio Mata; Pablo Mir; Pau Pastor; Joseph F Quinn; Shannon L Rhodes; Renee Ribacoba; Beate Ritz; John W Roberts; Ali Samii; María Sierra; Vivianna M Van Deerlin; Jia Y Wan; Dora Yearout; Pinky Agarwal; Victoria Alvarez; Harvey Checkoway; Kathryn A Chung; Amy Colcher; Karen L Edwards; Federico M Farin; Pilar Gómez-Garre; Carolyn M Hutter; Jon Infante; Hojoong M Kim; Oswaldo Lorenzo-Betancor; Erica Martinez; Cyrus Zabetian
Common variation in the LRRK2 gene is a risk factor for Parkinson's disease.
Taye H Hamza; Erin M Hill-Burns; Denise M Kay; Kenneth S Kendler; Victoria I Kusel; Jennifer S Montimurro; John G Nutt; Yikyung Park; Shannon L Rhodes; Beate Ritz; John W Roberts; Ali Samii; William Scott; Patricia Sheehan; Albert Tenesa; Jeffery Vance; Liyong Wang; Dora Yearout; Cyrus Zabetian; Pinky Agarwal; Silviu-Alin Bacanu; Yvette Bordelon; Honglei Chen; Muthukrishnan Eaaswarkhanth; Stewart A Factor; Jianjun Gao; Haydeh Payami
Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee.

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All Publications

2013: Taryn O Hall; Kathleen F Kerr; Ignacio F Mata; John W Roberts; Ali Samii; Katherine W Snapinn; Jia Y Wan; Cyrus Zabetian; Pinky Agarwal; Karen L Edwards
Risk prediction for complex diseases: application to Parkinson disease.
Genetics in medicine : official journal of the American College of Medical Genetics 2013;15(5):361-7.
2012: Ignacio Mata; Pablo Mir; Pau Pastor; Joseph F Quinn; Shannon L Rhodes; Renee Ribacoba; Beate Ritz; John W Roberts; Ali Samii; María Sierra; Vivianna M Van Deerlin; Jia Y Wan; Dora Yearout; Pinky Agarwal; Victoria Alvarez; Harvey Checkoway; Kathryn A Chung; Amy Colcher; Karen L Edwards; Federico M Farin; Pilar Gómez-Garre; Carolyn M Hutter; Jon Infante; Hojoong M Kim; Oswaldo Lorenzo-Betancor; Erica Martinez; Cyrus Zabetian
Common variation in the LRRK2 gene is a risk factor for Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(14):1822-5.
2011: Taye H Hamza; Erin M Hill-Burns; Denise M Kay; Kenneth S Kendler; Victoria I Kusel; Jennifer S Montimurro; John G Nutt; Yikyung Park; Shannon L Rhodes; Beate Ritz; John W Roberts; Ali Samii; William Scott; Patricia Sheehan; Albert Tenesa; Jeffery Vance; Liyong Wang; Dora Yearout; Cyrus Zabetian; Pinky Agarwal; Silviu-Alin Bacanu; Yvette Bordelon; Honglei Chen; Muthukrishnan Eaaswarkhanth; Stewart A Factor; Jianjun Gao; Haydeh Payami
Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee.
PLoS genetics 2011;7(8):e1002237.
2010: Ignacio Mata; Min Shi; Pinky Agarwal; Kathryn A Chung; Karen L Edwards; Stewart A Factor; Douglas Galasko; Carmen Ginghina; Alida Griffith; Donald S Higgins; Denise M Kay; Hojoong Kim; James B Leverenz; Joseph F Quinn; John W Roberts; Ali Samii; Katherine W Snapinn; Debby W Tsuang; Dora Yearout; Jing Zhang; Haydeh Payami; Cyrus Zabetian
SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.
Archives of neurology 2010;67(11):1350-6.
2010: Denise M Kay; C F Stevens; Taye H Hamza; Jennifer S Montimurro; Cyrus Zabetian; Stewart A Factor; Ali Samii; Alida Griffith; John W Roberts; E S Molho; Donald S Higgins; S Gancher; Lina Moses; S Zareparsi; Parvoneh Poorkaj-Navas; Thomas D Bird; John G Nutt; Gerard D Schellenberg; Haydeh Payami
A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2.
Neurology 2010;75(13):1189-94.
2010: Clement E Furlong; S M Suzuki; R C Stevens; J Marsillach; Rebecca J Richter; Gail P Jarvik; Harvey Checkoway; Ali Samii; Lucio G Costa; Alida Griffith; John W Roberts; Dora Yearout; Cyrus Zabetian
Human PON1, a biomarker of risk of disease and exposure.
Chemico-biological interactions 2010;187(1-3):355-61.
2010: Taye H Hamza; Cyrus P Zabetian; Albert Tenesa; Alain Laederach; Jennifer S Montimurro; Dora Yearout; Denise M Kay; Kimberly F Doheny; Justin Paschall; Elizabeth Pugh; Victoria I Kusel; Randall Collura; John Roberts; Alida Griffith; Ali Samii; William Scott; John G Nutt; Stewart A Factor; Haydeh Payami
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.
Nature genetics 2010;42(9):781-5.
2010: Parvoneh Poorkaj-Navas; Wendy H Raskind; James B Leverenz; Mark Matsushita; Cyrus P Zabetian; Ali Samii; Sophia Kim; Nayiry Gazi; John G Nutt; John Wolff; Dora Yearout; J Lynne Greenup; Ellen J Steinbart; Thomas D Bird
A novel X-linked four-repeat tauopathy with Parkinsonism and spasticity.
Movement disorders : official journal of the Movement Disorder Society 2010;25(10):1409-17.
2010: Valerie E Kelly; Shawn M Israel; Ali Samii; Jefferson C Slimp; Robert Goodkin; Anne Shumway-Cook
Assessing the effects of subthalamic nucleus stimulation on gait and mobility in people with Parkinson disease.
Disability and rehabilitation 2010;32(11):929-36.
2009: Kurt E Weaver; Todd L Richards; Olivia Liang; Mercy Y Laurino; Ali Samii; Elizabeth H Aylward
Longitudinal diffusion tensor imaging in Huntington's Disease.
Experimental neurology 2009;216(2):525-9.
2009: Ali Samii; Mahyar Etminan; Matthew O Wiens; Siavash Jafari
NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies.
Drugs & aging 2009;26(9):769-79.
2008: Ali Samii; Bruce C Carleton; Mahyar Etminan
Statin use and the risk of Parkinson disease: a nested case control study.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2008;15(11):1272-3.
2008: Denise M Kay; Stewart A Factor; Ali Samii; Donald S Higgins; Alida Griffith; John W Roberts; Berta C Leis; John G Nutt; Jennifer S Montimurro; Robert G Keefe; April J Atkins; Dora Yearout; Cyrus Zabetian; Haydeh Payami
Genetic association between alpha-synuclein and idiopathic Parkinson's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1222-30.
2008: Lucinda A Grande; John D Loeser; Ali Samii
Recurrent transient global amnesia with intrathecal baclofen.
Anesthesia and analgesia 2008;106(4):1284-7, table of contents.
2008: Colin C McCulloch; Denise M Kay; Stewart A Factor; Ali Samii; John G Nutt; Donald S Higgins; Alida Griffith; John W Roberts; Berta C Leis; Jennifer S Montimurro; Cyrus Zabetian; Haydeh Payami
Exploring gene-environment interactions in Parkinson's disease.
Human genetics 2008;123(3):257-65.
2008: Ignacio F Mata; Ali Samii; Seth H Schneer; John W Roberts; Alida Griffith; Berta C Leis; Gerard D Schellenberg; Ellen Sidransky; Thomas D Bird; James B Leverenz; Debby W Tsuang; Cyrus Zabetian
Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders.
Archives of neurology 2008;65(3):379-82.
2008: Carolyn M Hutter; Ali Samii; Stewart A Factor; John G Nutt; Donald S Higgins; Thomas D Bird; Alida Griffith; John W Roberts; Berta C Leis; Jennifer S Montimurro; Denise M Kay; Karen L Edwards; Haydeh Payami; Cyrus Zabetian
Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2008;15(2):134-9.
2008: Karen M Powers; Denise M Kay; Stewart A Factor; Cyrus Zabetian; Donald S Higgins; Ali Samii; John G Nutt; Alida Griffith; Berta Leis; John W Roberts; Erica D Martinez; Jennifer S Montimurro; Harvey Checkoway; Haydeh Payami
Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk.
Movement disorders : official journal of the Movement Disorder Society 2008;23(1):88-95.
2007: Cyrus Zabetian; Carolyn M Hutter; Stewart A Factor; John G Nutt; Donald S Higgins; Alida Griffith; John W Roberts; Berta C Leis; Denise M Kay; Dora Yearout; Jennifer S Montimurro; Karen L Edwards; Ali Samii; Haydeh Payami
Association analysis of MAPT H1 haplotype and subhaplotypes in Parkinson's disease.
Annals of neurology 2007;62(2):137-44.
2007: Ali Samii; Valerie E Kelly; Jefferson C Slimp; Anne Shumway-Cook; Robert Goodkin
Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(10):1476-81.
2007: Lani S Chun; Ali Samii; Carolyn M Hutter; Alida Griffith; John W Roberts; Berta C Leis; Anthony D Mosley; P Luke Wander; Karen L Edwards; Haydeh Payami; Cyrus Zabetian
DBH -1021C-->T does not modify risk or age at onset in Parkinson's disease.
Annals of neurology 2007;62(1):99-101.
2007: Melanie Walker; Hojoong Kim; Ali Samii
Holmes-like tremor of the lower extremity following brainstem hemorrhage.
Movement disorders : official journal of the Movement Disorder Society 2007;22(2):272-4.
2007: Ali Samii; Jefferson C Slimp; Janna L Friedly; Robert Goodkin
Spinal accessory neuropathy after deep brain stimulation for Parkinson's disease.
Stereotactic and functional neurosurgery 2007;85(6):296-8.
2006: Valerie E Kelly; Ali Samii; Jefferson C Slimp; Robert Price; Robert Goodkin; Anne Shumway-Cook
Gait changes in response to subthalamic nucleus stimulation in people with Parkinson disease: a case series report.
Journal of neurologic physical therapy : JNPT 2006;30(4):184-94.
2006: Alexis Elbaz; Lorene Nelson; Haydeh Payami; John Ioannidis; Brian Fiske; Grazia Annesi; Andrea Carmine Belin; Stewart A Factor; Carlo Ferrarese; Georgios M Hadjigeorgiou; Donald S Higgins; Hideshi Kawakami; Rejko Krüger; Karen Marder; Richard Mayeux; George D Mellick; John G Nutt; Beate Ritz; Ali Samii; Caroline M Tanner; Christine Van Broeckhoven; Stephen K Van Den Eeden; Karin Wirdefeldt; Cyrus Zabetian; Marie Dehem; Jennifer S Montimurro; Audrey Southwick; Richard Myers; Thomas A Trikalinos
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study.
Lancet neurology 2006;5(11):917-23.
2006: Cyrus Zabetian; Carolyn M Hutter; Dora Yearout; Alexis N Lopez; Stewart A Factor; Alida Griffith; Berta C Leis; Thomas D Bird; John G Nutt; Donald S Higgins; John W Roberts; Denise M Kay; Karen L Edwards; Ali Samii; Haydeh Payami
LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago.
American journal of human genetics 2006;79(4):752-8.
2006: Cyrus Zabetian; H Morino; H Ujike; M Yamamoto; M Oda; H Maruyama; Y Izumi; R Kaji; Alida Griffith; Berta C Leis; John W Roberts; Dora Yearout; Ali Samii; H Kawakami
Identification and haplotype analysis of LRRK2 G2019S in Japanese patients with Parkinson disease.
Neurology 2006;67(4):697-9.
2006: Denise M Kay; Cyrus Zabetian; Stewart A Factor; John G Nutt; Ali Samii; Alida Griffith; Thomas D Bird; Patricia L Kramer; Donald S Higgins; Haydeh Payami
Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics.
Movement disorders : official journal of the Movement Disorder Society 2006;21(4):519-23.
2006: Denise M Kay; Thomas D Bird; Cyrus Zabetian; Stewart A Factor; Ali Samii; Donald S Higgins; John G Nutt; John W Roberts; Alida Griffith; Berta C Leis; Jennifer S Montimurro; Sean Philpott; Haydeh Payami
Validity and utility of a LRRK2 G2019S mutation test for the diagnosis of Parkinson's disease.
Genetic testing 2006;10(3):221-7.
2006: Melanie Walker; Ali Samii
Chronic severe dystonia after single exposure to antiemetics.
The American journal of emergency medicine 2006;24(1):125-7.
2005: Cyrus Zabetian; Ali Samii; A D Mosley; John W Roberts; Berta C Leis; Dora Yearout; Wendy H Raskind; Alida Griffith
A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations.
Neurology 2005;65(5):741-4.
2005: Ali Samii; Jefferson C Slimp; Patrick J Hogan; Robert Goodkin
Deep brain stimulation in a patient on immunosuppressive therapy after renal transplant.
Parkinsonism & related disorders 2005;11(4):259-60.
2005: Ali Samii; Jefferson C Slimp; Robert Goodkin
Unilateral subthalamic nucleus deep brain stimulation contralateral to thalamic stimulation in Parkinson disease.
Parkinsonism & related disorders 2005;11(4):257-8.
2005: Snjezana Zaja-Milatovic; Dejan Milatovic; Aimee M Schantz; Jing Zhang; Kathleen S Montine; Ali Samii; Ariel Deutch; Thomas J Montine
Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease.
Neurology 2005;64(3):545-7.
2004: Melanie Walker; Ali Samii; Thomas D Bird
Coexistence of tuberous sclerosis and Friedreich ataxia.
Journal of the neurological sciences 2004;221(1-2):91-3.
2004: Melanie Walker; Ali Samii
Delayed onset of ataxia in a patient with short bowel syndrome: a case of vitamin E deficiency.
Nutritional neuroscience 2004;7(3):191-3.
2004: Ali Samii; John G Nutt; Bruce R Ransom
Parkinson's disease.
Lancet 2004;363(9423):1783-93.
2004: A Alex Mohit; Ali Samii; Jefferson C Slimp; M Sean Grady; Robert Goodkin
Mechanical failure of the electrode wire in deep brain stimulation.
Parkinsonism & related disorders 2004;10(3):153-6.
2003: Ali Samii; Debra D Dahlen; Alexander M Spence; Nicole C Maronian; Eric E Kraus; Vanda A Lennon
Paraneoplastic movement disorder in a patient with non-Hodgkin's lymphoma and CRMP-5 autoantibody.
Movement disorders : official journal of the Movement Disorder Society 2003;18(12):1556-8.
2003: Ali Samii; Monique L Giroux; Jefferson C Slimp; Robert Goodkin
Bilateral subthalamic nucleus stimulation after bilateral pallidotomies in a patient with advanced Parkinson's disease.
Parkinsonism & related disorders 2003;9(3):159-62.