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Melanie Samuel

Research Profile

Living Beings

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West Nile Fever

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Publications

TOP 3
Katherine L Hussmann; Kwang S Kim; Melanie A Samuel; Michael S Diamond; Brenda L Fredericksen
Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes.
Kristy Szretter; Melanie A Samuel; Susan Gilfillan; Anja Fuchs; Marco COLONna; Michael S Diamond
The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis.
Stephane Daffis; Melanie A Samuel; Mehul S Suthar; Michael Gale; Michael S Diamond
Toll-like receptor 3 has a protective role against West Nile virus infection.

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All Publications

2013: Katherine L Hussmann; Kwang S Kim; Melanie A Samuel; Michael S Diamond; Brenda L Fredericksen
Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes.
Journal of virology 2013;87(5):2814-22.
2009: Kristy Szretter; Melanie A Samuel; Susan Gilfillan; Anja Fuchs; Marco COLONna; Michael S Diamond
The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis.
Journal of virology 2009;83(18):9329-38.
2008: Stephane Daffis; Melanie A Samuel; Mehul S Suthar; Michael Gale; Michael S Diamond
Toll-like receptor 3 has a protective role against West Nile virus infection.
Journal of virology 2008;82(21):10349-58.
2008: Stephane Daffis; Melanie A Samuel; Mehul S Suthar; Brian C Keller; Michael Gale; Michael S Diamond
Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.
Journal of virology 2008;82(17):8465-75.
2007: Melanie A Samuel; Hong Wang; Venkatraman Siddharthan; John D Morrey; Michael S Diamond
Axonal transport mediates West Nile virus entry into the central nervous system and induces acute flaccid paralysis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17140-5.
2007: Stephane Daffis; Melanie A Samuel; Brian C Keller; Michael Gale; Michael S Diamond
Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms.
PLoS pathogens 2007;3(7):e106.
2007: Melanie A Samuel; John D Morrey; Michael S Diamond
Caspase 3-dependent cell death of neurons contributes to the pathogenesis of West Nile virus encephalitis.
Journal of virology 2007;81(6):2614-23.
2006: Brian C Keller; Brenda L Fredericksen; Melanie A Samuel; Richard E Mock; Peter W Mason; Michael S Diamond; Michael Gale
Resistance to alpha/beta interferon is a determinant of West Nile virus replication fitness and virulence.
Journal of virology 2006;80(19):9424-34.
2006: Melanie A Samuel; Michael S Diamond
Pathogenesis of West Nile Virus infection: a balance between virulence, innate and adaptive immunity, and viral evasion.
Journal of virology 2006;80(19):9349-60.
2006: Melanie A Samuel; Kevin Whitby; Brian C Keller; Anantha Marri; Winfried Barchet; Bryan R G Williams; Robert H Silverman; Michael Gale; Michael S Diamond
PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons.
Journal of virology 2006;80(14):7009-19.
2006: Bimmi Shrestha; Tian Wang; Melanie A Samuel; Kevin Whitby; Joe Craft; Erol Fikrig; Michael S Diamond
Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection.
Journal of virology 2006;80(11):5338-48.
2006: Sergey A Shiryaev; Boris I Ratnikov; Alexei V Chekanov; Sergey Sikora; Dmitri V Rozanov; Adam Godzik; Jun Wang; Jeffrey W Smith; Ziwei Huang; Iris Lindberg; Melanie A Samuel; Michael S Diamond; Alex Y Strongin
Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase.
The Biochemical journal 2006;393(Pt 2):503-11.
2006: Bimmi Shrestha; Melanie A Samuel; Michael S Diamond
CD8+ T cells require perforin to clear West Nile virus from infected neurons.
Journal of virology 2006;80(1):119-29.
2005: Melanie A Samuel; Michael S Diamond
Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival.
Journal of virology 2005;79(21):13350-61.
2005: Robyn S Klein; Eugene Lin; Bo Zhang; Andrew D Luster; Judy Tollett; Melanie A Samuel; Michael Engle; Michael S Diamond
Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis.
Journal of virology 2005;79(17):11457-66.
2005: Theodore C Pierson; Michael S Diamond; Asim A Ahmed; Laura E Valentine; Carl W Davis; Melanie A Samuel; Sheri L Hanna; Bridget A Puffer; Robert W Doms
An infectious West Nile virus that expresses a GFP reporter gene.
Virology 2005;334(1):28-40.