Jesús San Miguel

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Santamaría Carlos M; Chillón Maria C; García-Sanz Ramón; Pérez Cristina; Caballero María D; Ramos Fernando; de Coca Alfonso García; Alonso José M; Giraldo Pilar; Bernal Teresa; Queizán José A; Rodriguez Juan N; Fernández-Abellán Pascual; Bárez Abelardo; Peñarrubia María J; Vidriales María B; Balanzategui Ana; Sarasquete María E; Alcoceba Miguel; Díaz-Mediavilla Joaquín; San Miguel Jesús F; Gonzalez Marcos
High FOXO3a expression is associated with a poorer prognosis in AML with normal cytogenetics.
Paiva Bruno; Vidriales Maria-Belén; Pérez Jose J; Mateo Gema; Montalbán Maria Angeles; Mateos Maria Victoria; Bladé Joan; Lahuerta Juan José; Orfao Alberto; San Miguel Jesús F;
Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessment in myeloma patients.
Villanueva Fernanda N; Pérez-Simón Jose Antonio; Silva Fernando F; Caballero-Velázquez Teresa T; Sánchez-Guijo Fermin F; Cañizo Conzuelo C; Vázquez Lourdes L; Caballero Dolores D; San Miguel Jesús F
Oral beclomethasone dipropionate for the treatment of gastrointestinal chronic graft-versus-host disease.

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2009: Santamaría Carlos M; Chillón Maria C; García-Sanz Ramón; Pérez Cristina; Caballero María D; Ramos Fernando; de Coca Alfonso García; Alonso José M; Giraldo Pilar; Bernal Teresa; Queizán José A; Rodriguez Juan N; Fernández-Abellán Pascual; Bárez Abelardo; Peñarrubia María J; Vidriales María B; Balanzategui Ana; Sarasquete María E; Alcoceba Miguel; Díaz-Mediavilla Joaquín; San Miguel Jesús F; Gonzalez Marcos
High FOXO3a expression is associated with a poorer prognosis in AML with normal cytogenetics.
Leukemia research 2009;33(12):1706-9.
2009: Paiva Bruno; Vidriales Maria-Belén; Pérez Jose J; Mateo Gema; Montalbán Maria Angeles; Mateos Maria Victoria; Bladé Joan; Lahuerta Juan José; Orfao Alberto; San Miguel Jesús F;
Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessment in myeloma patients.
Haematologica 2009;94(11):1599-602.
2009: Villanueva Fernanda N; Pérez-Simón Jose Antonio; Silva Fernando F; Caballero-Velázquez Teresa T; Sánchez-Guijo Fermin F; Cañizo Conzuelo C; Vázquez Lourdes L; Caballero Dolores D; San Miguel Jesús F
Oral beclomethasone dipropionate for the treatment of gastrointestinal chronic graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(10):1331-6.
2009: Garayoa M; Garcia J L; Santamaria C; Garcia-Gomez A; Blanco J F; Pandiella A; Hernández J M; Sanchez-Guijo F M; del Cañizo M-C; Gutiérrez N C; San Miguel J F
Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(8):1515-27.
2009: Blanco Belén; Pérez-Simón José A; Sánchez-Abarca Luis I; Caballero-Velazquez Teresa; Gutierrez-Cossío Silvia; Hernández-Campo Pilar; Díez-Campelo María; Herrero-Sanchez Carmen; Rodriguez-Serrano Concepción; Santamaría Carlos; Sánchez-Guijo Fermín M; Del Cañizo Consuelo; San Miguel Jesús F
Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population.
Haematologica 2009;94(7):975-83.
2009: Santamaría Carlos M; Chillón María C; García-Sanz Ramón; Pérez Cristina; Caballero María D; Ramos Fernando; de Coca Alfonso García; Alonso José M; Giraldo Pilar; Bernal Teresa; Queizán José A; Rodriguez Juan N; Fernández-Abellán Pascual; Bárez Abelardo; Peñarrubia María J; Balanzategui Ana; Vidriales María B; Sarasquete María E; Alcoceba Miguel; Díaz-Mediavilla Joaquín; San Miguel Jesús F; Gonzalez Marcos
Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia.
Blood 2009;114(1):148-52.
2009: Stadtmauer Edward A; Weber Donna M; Niesvizky Ruben; Belch Andrew; Prince Miles H; San Miguel Jesús F; Facon Thierry; Olesnyckyj Marta; Yu Zhinuan; Zeldis Jerome B; Knight Robert D; Dimopoulos Meletios A
Lenalidomide in combination with dexamethasone at first relapse in comparison with its use as later salvage therapy in relapsed or refractory multiple myeloma.
European journal of haematology 2009;82(6):426-32.
2009: Lopez-Villar O; Garcia J L; Sanchez-Guijo F M; Robledo C; Villaron E M; Hernández-Campo P; Lopez-Holgado N; Diez-Campelo M; Barbado M V; Perez-Simon J A; Hernández-Rivas J M; San-Miguel J F; del Cañizo M-C
Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q- syndrome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(4):664-72.
2009: Ocio Enrique M; Maiso Patricia; Chen Xi; Garayoa Mercedes; Alvarez-Fernández Stela; San-Segundo Laura; Vilanova David; López-Corral Lucía; Montero Juan C; Hernández-Iglesias Teresa; de Alava Enrique; Galmarini Carlos; Avilés Pablo; Cuevas Carmen; San-Miguel Jesús F; Pandiella Atanasio
Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks.
Blood 2009;113(16):3781-91.
2009: Hernández José Angel; Rodríguez Ana Eugenia; González Marcos; Benito Rocío; Fontanillo Celia; Sandoval Virgilio; Romero Mercedes; Martín-Núñez Guillermo; de Coca Alfonso García; Fisac Rosa; Galende Josefina; Recio Isabel; Ortuño Francisco; García Juan Luis; de las Rivas Javier; Gutiérrez Norma Carmen; San Miguel Jesús F; Hernández Jesús María
A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemia.
Haematologica 2009;94(3):364-71.
2008: Bladé Joan; Sonneveld Pieter; San Miguel Jesús F; Sutherland Heather J; Hajek Roman; Nagler Arnon; Spencer Andrew; Robak Tadeusz; Cibeira M Teresa; Zhuang Sen H; Harousseau Jean-Luc; Orlowski Robert Z;
Pegylated liposomal doxorubicin plus bortezomib in relapsed or refractory multiple myeloma: efficacy and safety in patients with renal function impairment.
Clinical lymphoma & myeloma 2008;8(6):352-5.
2008: Ocio Enrique M; Mateos María-Victoria; Maiso Patricia; Pandiella Atanasio; San-Miguel Jesús F
New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings.
The lancet oncology 2008;9(12):1157-65.
2008: Lahuerta Juan José; Mateos Maria Victoria; Martínez-López Joaquin; Rosiñol Laura; Sureda Anna; de la Rubia Javier; García-Laraña José; Martínez-Martínez Rafael; Hernández-García Miguel T; Carrera Dolores; Besalduch Joan; de Arriba Felipe; Ribera José María; Escoda Lourdes; Hernández-Ruiz Belén; García-Frade Javier; Rivas-González Concepción; Alegre Adrían; Bladé Joan; San Miguel Jesús F
Influence of pre- and post-transplantation responses on outcome of patients with multiple myeloma: sequential improvement of response and achievement of complete response are associated with longer survival.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(35):5775-82.
2008: Santamaría Carlos; Chillón María Carmen; García-Sanz Ramón; Balanzategui Ana; Sarasquete María Eugenia; Alcoceba Miguel; Ramos Fernando; Bernal Teresa; Queizán José Antonio; Peñarrubia María Jesús; Giraldo Pilar; San Miguel Jesús F; Gonzalez Marcos
The relevance of preferentially expressed antigen of melanoma (PRAME) as a marker of disease activity and prognosis in acute promyelocytic leukemia.
Haematologica 2008;93(12):1797-805.
2008: Lee Stephanie J; Richardson Paul G; Sonneveld Pieter; Schuster Michael W; Irwin David; San Miguel Jesús-F; Crawford Bruce; Massaro Joseph; Dhawan Ravinder; Gupta Sanjay; Anderson Kenneth C
Bortezomib is associated with better health-related quality of life than high-dose dexamethasone in patients with relapsed multiple myeloma: results from the APEX study.
British journal of haematology 2008;143(4):511-9.
2008: Paiva Bruno; Vidriales Maria-Belén; Cerveró Jorge; Mateo Gema; Pérez Jose J; Montalbán Maria A; Sureda Anna; Montejano Laura; Gutiérrez Norma C; García de Coca Alfonso; de Las Heras Natalia; Mateos Maria V; López-Berges Maria C; García-Boyero Raimundo; Galende Josefina; Hernández Jose; Palomera Luis; Carrera Dolores; Martínez Rafael; de la Rubia Javier; Martín Alejandro; Bladé Joan; Lahuerta Juan J; Orfao Alberto; San Miguel Jesús F;
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
Blood 2008;112(10):4017-23.
2008: Alcoceba Miguel; Balanzategui Ana; Díez-Campelo Maria; Martín-Jiménez Patricia; Sarasquete Maria Eugenia; Chillón M Carmen; Santamaría Carlos; Pérez-Simón Jose Antonio; Marín Luis; Caballero M Dolores; San Miguel Jesús F; García-Sanz Ramón; González Marcos
Clinical and prognostic value of discrepancies in microsatellite DNA regions between recipient and donor in human leukocyte antigen-identical allogeneic transplantation setting.
Transplantation 2008;86(7):983-90.
2008: Ayuk Francis; Perez-Simon José A; Shimoni Avichai; Sureda Anna; Zabelina Tatjana; Schwerdtfeger Rainer; Martino Rodrigo; Sayer Herbert Gottfried; Alegre Adrián; Lahuerta Juan-José; Atanackovic Djordje; Wolschke Christine; Nagler Arnon; Zander Axel R; San Miguel Jesús F; Kröger Nicolaus
Clinical impact of human Jurkat T-cell-line-derived antithymocyte globulin in multiple myeloma patients undergoing allogeneic stem cell transplantation.
Haematologica 2008;93(9):1343-50.
2008: Tabera Soraya; Pérez-Simón José A; Díez-Campelo María; Sánchez-Abarca Luis I; Blanco Belén; López Antonio; Benito Ana; Ocio Enrique; Sánchez-Guijo Fermín M; Cañizo Consuelo; San Miguel Jesús F
The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes.
Haematologica 2008;93(9):1301-9.
2008: San Miguel Jesús F; Schlag Rudolf; Khuageva Nuriet K; Dimopoulos Meletios A; Shpilberg Ofer; Kropff Martin; Spicka Ivan; Petrucci Maria T; Palumbo Antonio; Samoilova Olga S; Dmoszynska Anna; Abdulkadyrov Kudrat M; Schots Rik; Jiang Bin; Mateos Maria-Victoria; Anderson Kenneth C; Esseltine Dixie L; Liu Kevin; Cakana Andrew; van de Velde Helgi; Richardson Paul G;
Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma.
The New England journal of medicine 2008;359(9):906-17.
2008: Carrancio Soraya; López-Holgado Natalia; Sánchez-Guijo Fermín M; Villarón Eva; Barbado Victoria; Tabera Soraya; Díez-Campelo María; Blanco Juan; San Miguel Jesús F; Del Cañizo M Consuelo
Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification.
Experimental hematology 2008;36(8):1014-21.
2008: Pérez-Simón Jose A; Martino Rodrigo; Caballero Dolores; Valcarcel David; Rebollo Noemi; de la Cámara Rafael; de Oteiza Javier Pérez; Heras Inmaculada; Calvo Maria V; Sierra Jordi; San Miguel Jesús F;
Reduced-intensity conditioning allogeneic transplantation from unrelated donors: evaluation of mycophenolate mofetil plus cyclosporin A as graft-versus-host disease prophylaxis.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(6):664-71.
2008: Mateo Gema; Montalbán M Angeles; Vidriales Maria-Belén; Lahuerta Juan J; Mateos Maria V; Gutiérrez Norma; Rosiñol Laura; Montejano Laura; Bladé Joan; Martínez Rafael; de la Rubia Javier; Diaz-Mediavilla Joaquín; Sureda Anna; Ribera José M; Ojanguren José M; de Arriba Felipe; Palomera Luis; Terol Maria J; Orfao Alberto; San Miguel Jesús F;
Prognostic value of immunophenotyping in multiple myeloma: a study by the PETHEMA/GEM cooperative study groups on patients uniformly treated with high-dose therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(16):2737-44.
2008: Montero Juan Carlos; López-Pérez Ricardo; San Miguel Jesús F; Pandiella Atanasio
Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity.
Haematologica 2008;93(6):851-9.
2008: Alcoceba M; Marín L; Balanzategui A; Sarasquete M E; Martín-Jiménez P; Chillón M C; Corral R; Pérez-Persona E; Fernández-Calvo F J; Hernández J M; Bladé J; Lahuerta J J; González M; San Miguel J F; García-Sanz R
The presence of DRB1*01 allele in multiple myeloma patients is associated with an indolent disease.
Tissue antigens 2008;71(6):548-51.
2008: Maiso Patricia; Ocio Enrique M; Garayoa Mercedes; Montero Juan C; Hofmann Francesco; García-Echeverría Carlos; Zimmermann Johann; Pandiella Atanasio; San Miguel Jesús F
The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells.
British journal of haematology 2008;141(4):470-82.
2008: Mateos María-Victoria; Hernández José M; Hernández Miguel T; Gutiérrez Norma C; Palomera Luis; Fuertes Marta; Garcia-Sanchez Pedro; Lahuerta Juán J; de la Rubia Javier; Terol María-José; Sureda Ana; Bargay Joan; Ribas Paz; Alegre Adrian; de Arriba Felipe; Oriol Albert; Carrera Dolores; García-Laraña José; García-Sanz Ramón; Bladé Joan; Prósper Felipe; Mateo Gemma; Esseltine Dixie-Lee; van de Velde Helgi; San Miguel Jesús F
Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: updated time-to-events results and prognostic factors for time to progression.
Haematologica 2008;93(4):560-5.
2008: San-Miguel J F; Richardson P G; Sonneveld P; Schuster M W; Irwin D; Stadtmauer E A; Facon T; Harousseau J-L; Ben-Yehuda D; Lonial S; Goldschmidt H; Reece D; Bladé J; Boccadoro M; Cavenagh J D; Neuwirth R; Boral A L; Esseltine D-L; Anderson K C
Efficacy and safety of bortezomib in patients with renal impairment: results from the APEX phase 3 study.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(4):842-9.
2008: Martín-Ayuso Marta; Almeida Julia; Pérez-Andrés Martín; Cuello Rebeca; Galende Josefina; González-Fraile Maria Isabel; Martín-Nuñez Guillermo; Ortega Fernando; Rodríguez Maria Jesús; San Miguel Jesús F; Orfao Alberto
Peripheral blood dendritic cell subsets from patients with monoclonal gammopathies show an abnormal distribution and are functionally impaired.
The oncologist 2008;13(1):82-92.
2008: Colado Enrique; Alvarez-Fernández Stela; Maiso Patricia; Martín-Sánchez Jesús; Vidriales Maria Belén; Garayoa Mercedes; Ocio Enrique M; Montero Juan Carlos; Pandiella Atanasio; San Miguel Jesús F
The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype.
Haematologica 2008;93(1):57-66.
2007: Mateos M V; San Miguel J F
Bortezomib in multiple myeloma.
Best practice & research. Clinical haematology 2007;20(4):701-15.
2007: Martín-Jiménez Patricia; García-Sanz Ramón; González David; Balanzategui Ana; Pérez José J; Caballero M Dolores; Sarasquete M Eugenia; Galende Josefina; Orfao Alberto; López-Berges M Consuelo; San Miguel Jesús F; González Marcos
Molecular characterization of complete and incomplete immunoglobulin heavy chain gene rearrangements in hairy cell leukemia.
Clinical lymphoma & myeloma 2007;7(9):573-9.
2007: González David; van der Burg Mirjam; García-Sanz Ramón; Fenton James A; Langerak Anton W; González Marcos; van Dongen Jacques J M; San Miguel Jesus F; Morgan Gareth J
Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma.
Blood 2007;110(9):3112-21.
2007: Villaron E M; Almeida J; Lopez-Holgado N; Sanchez-Guijo F M; Alberca M; Blanco B; Sanchez-Abarca L I; Lopez O; Perez-Simon J A; San Miguel J F; del Cañizo M C
In leukapheresis products from non-Hodgkin's lymphoma patients, the immature hematopoietic progenitors show higher CD90 and CD34 antigenic expression.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2007;37(2):145-56.
2007: Pérez-Persona Ernesto; Vidriales María-Belén; Mateo Gema; García-Sanz Ramón; Mateos Maria-Victoria; de Coca Alfonso García; Galende Josefina; Martín-Nuñez Guillermo; Alonso José M; de Las Heras Natalia; Hernández José M; Martín Alejandro; López-Berges Consuelo; Orfao Alberto; San Miguel Jesús F
New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells.
Blood 2007;110(7):2586-92.
2007: Bagán José; Blade Juan; Cozar Jose Manuel; Constela Manuel; García Sanz Ramón; Gómez Veiga Francisco; Lahuerta Juan José; Lluch Ana; Massuti Bartomeu; Morote Juan; San Miguel Jesús F; Solsona Eduardo
Recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates.
Medicina oral, patología oral y cirugía bucal 2007;12(4):E336-40.
2007: García-Sanz Ramón; Mateos María Victoria; San Miguel Jesús Fernando
[Multiple myeloma]
Medicina clínica 2007;129(3):104-15.
2007: Richardson Paul G; Sonneveld Pieter; Schuster Michael W; Irwin David; Stadtmauer Edward A; Facon Thierry; Harousseau Jean-Luc; Ben-Yehuda Dina; Lonial Sagar; San Miguel Jesús-F; Cavenagh Jamie D; Anderson Kenneth C
Safety and efficacy of bortezomib in high-risk and elderly patients with relapsed multiple myeloma.
British journal of haematology 2007;137(5):429-35.
2007: Ramirez J M; Ocio E M; San Miguel J F; Pandiella A
Pemetrexed acts as an antimyeloma agent by provoking cell cycle blockade and apoptosis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(4):797-804.
2007: Santamaría Carlos; Chillón Maria Carmen; Fernández Carina; Martín-Jiménez Patricia; Balanzategui Ana; García Sanz Ramón; San Miguel Jesús F; González Marcos-Gonzalez
Using quantification of the PML-RARalpha transcript to stratify the risk of relapse in patients with acute promyelocytic leukemia.
Haematologica 2007;92(3):315-22.
2007: Gutiérrez N C; Ocio E M; de Las Rivas J; Maiso P; Delgado M; Fermiñán E; Arcos M J; Sánchez M L; Hernández J M; San Miguel J F
Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(3):541-9.
2007: Ocio E M; Schop R F J; Gonzalez B; Van Wier S A; Hernandez-Rivas J M; Gutierrez N C; Garcia-Sanz R; Moro M J; Aguilera C; Hernandez J; Xu R; Greipp P R; Dispenzieri A; Jalal S M; Lacy M Q; Gonzalez-Paz N; Gertz M A; San Miguel J F; Fonseca R
6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis.
British journal of haematology 2007;136(1):80-6.
2007: Martín-Jiménez Patricia; García-Sanz Ramón; Sarasquete María E; Ocio Enrique; Pérez José J; González Marcos; San Miguel Jesús F
Functional class switch recombination may occur 'in vivo' in Waldenström macroglobulinaemia.
British journal of haematology 2007;136(1):114-6.
2007: Gutiérrez N C; Castellanos M V; Martín M L; Mateos M V; Hernández J M; Fernández M; Carrera D; Rosiñol L; Ribera J M; Ojanguren J M; Palomera L; Gardella S; Escoda L; Hernández-Boluda J C; Bello J L; de la Rubia J; Lahuerta J J; San Miguel J F;
Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated with adverse prognosis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(1):143-50.
2007: López-Holgado N; Alberca M; Sánchez-Guijo F; Villarón E; Almeida J; Martín A; Armellini A; García C; Blanco B; Sánchez-Abarca I; Martín S; Pérez-Simón J A; García-Sanz R; San Miguel J F; del Cañizo M C
Short-term endothelial progenitor cell colonies are composed of monocytes and do not acquire endothelial markers.
Cytotherapy 2007;9(1):14-22.
2007: Gonzalez-Porras J R; Martin-Herrero F; Garcia-Sanz R; Lopez M L; Balanzategui A; Mateos M V; Pavon P; Gonzalez M; Alberca I; San Miguel J F
Hyperhomocysteinemia is a risk factor of recurrent coronary event in young patients irrespective to the MTHFR C677T polymorphism.
Thrombosis research 2007;119(6):691-8.
2006: García-Sanz R; Hernández J M; Sureda A; García-Laraña J; Prósper F; Alegre A; Bárez A; Mateos M V; San Miguel J F
Pegylated liposomal doxorubicin, melphalan and prednisone therapy for elderly patients with multiple myeloma.
Hematological oncology 2006;24(4):205-11.
2006: Escobar Ignacio Garcia; Barrigon Dolores Caballero; Tamayo Pilar; Perez-Simon Jose Antonio; Mateos Maria Vitoria; Garcia Jose Ramon; San Miguel Jesus F
Prognostic impact of pretransplantation computed tomography and gallium scans in patients with Hodgkin lymphoma with poor prognosis undergoing hematopoietic stem cell transplantation.
Clinical lymphoma & myeloma 2006;7(3):217-25.
2006: Sarasquete María Eugenia; García-Sanz Ramón; Armellini Adriana; Fuertes Marta; Martín-Jiménez Patricia; Sierra Magdalena; Del Carmen Chillón María; Alcoceba Miguel; Balanzategui Ana; Ortega Fernando; Hernández José Mariano; Sureda Anna; Palomera Luis; González Marcos; San Miguel Jesús Fernando
The association of increased p14ARF/p16INK4a and p15INK4a gene expression with proliferative activity and the clinical course of multiple myeloma.
Haematologica 2006;91(11):1551-4.
2006: Mateos María-Victoria; Hernández José-M; Hernández Miguel-T; Gutiérrez Norma-C; Palomera Luis; Fuertes Marta; Díaz-Mediavilla Joaquín; Lahuerta Juan-J; de la Rubia Javier; Terol María-José; Sureda Ana; Bargay Joan; Ribas Paz; de Arriba Felipe; Alegre Adrian; Oriol Albert; Carrera Dolores; García-Laraña José; García-Sanz Ramón; Bladé Joan; Prósper Felipe; Mateo Gemma; Esseltine Dixie-Lee; van de Velde Helgi; San Miguel Jesús-F
Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study.
Blood 2006;108(7):2165-72.
2006: Castilla C; Pérez-Simón J A; Sanchez-Guijo F M; Díez-Campelo M; Ocio E; Pérez-Persona E; López-Villar O; Vazquez L; Caballero D; San Miguel J F
Oral beclomethasone dipropionate for the treatment of gastrointestinal acute graft-versus-host disease (GVHD).
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(9):936-41.
2006: Sierra Magdalena; Alonso Alvaro; Odero M Dolores; Gonzalez M Belén; Lahortiga Idoia; Pérez José J; García Juan L; Gutiérrez Norma C; Calasanz María J; San Miguel Jesús F; Hernández Jesús M
Geographic differences in the incidence of cytogenetic abnormalities of acute myelogenous leukemia (AML) in Spain.
Leukemia research 2006;30(8):943-8.
2006: San Miguel Jesús F; Gutiérrez Norma C; Mateo Gema; Orfao Alberto
Conventional diagnostics in multiple myeloma.
European journal of cancer (Oxford, England : 1990) 2006;42(11):1510-9.
2006: Ramos Luis; de Las Heras José Antonio; Sánchez Sergio; González-Porras José Ramón; González Rafael; Mateos Maria Victoria; San Miguel Jesús F
Medium-term results of percutaneous vertebroplasty in multiple myeloma.
European journal of haematology 2006;77(1):7-13.
2006: van de Donk N W C J; Kröger N; Hegenbart U; Corradini P; San Miguel J F; Goldschmidt H; Perez-Simon J A; Zijlmans M; Raymakers R A; Montefusco V; Ayuk F A; van Oers M H J; Nagler A; Verdonck L F; Lokhorst H M
Prognostic factors for donor lymphocyte infusions following non-myeloablative allogeneic stem cell transplantation in multiple myeloma.
Bone marrow transplantation 2006;37(12):1135-41.
2006: Maiso Patricia; Carvajal-Vergara Xonia; Ocio Enrique M; López-Pérez Ricardo; Mateo Gema; Gutiérrez Norma; Atadja Peter; Pandiella Atanasio; San Miguel Jesús F
The histone deacetylase inhibitor LBH589 is a potent antimyeloma agent that overcomes drug resistance.
Cancer research 2006;66(11):5781-9.
2006: van de Donk Niels W C J; Kröger Nicolaus; Hegenbart Ute; Corradini Paolo; San Miguel Jesus F; Goldschmidt Hartmut; Perez-Simon Jose A; Zijlmans Mark; Raymakers Reinier A; Montefusco Vittorio; Ayuk Francis A; van Oers Marinus H J; Nagler Arnon; Verdonck Leo F; Lokhorst Henk M
Remarkable activity of novel agents bortezomib and thalidomide in patients not responding to donor lymphocyte infusions following nonmyeloablative allogeneic stem cell transplantation in multiple myeloma.
Blood 2006;107(8):3415-6.
2006: Sanchez Maria Luz; Almeida Julia; Lopez Antonio; Sayagues Jose Maria; Rasillo Ana; Sarasquete Eugenia A; Balanzategui Ana; Tabernero Maria Dolores; Diaz-Mediavilla Joaquin; Barrachina Carmen; Paiva Artur; Gonzalez Marcos; San Miguel Jesus F; Orfao Alberto
Heterogeneity of neoplastic cells in B-cell chronic lymphoproliferative disorders: biclonality versus intraclonal evolution of a single tumor cell clone.
Haematologica 2006;91(3):331-9.
2006: Pérez-Andres Martin; Almeida Julia; Martin-Ayuso Marta; Moro Maria Jesus; Martin-Nuñez Guillermo; Galende Josefina; Hernandez Jose; Mateo Gema; San Miguel Jesus F; Orfao Alberto;
Characterization of bone marrow T cells in monoclonal gammopathy of undetermined significance, multiple myeloma, and plasma cell leukemia demonstrates increased infiltration by cytotoxic/Th1 T cells demonstrating a squed TCR-Vbeta repertoire.
Cancer 2006;106(6):1296-305.
2006: Pérez-Simón J A; Sureda A; Fernández-Aviles F; Sampol A; Cabrera J R; Caballero D; Martino R; Petit J; Tomás J F; Moraleda J M; Alegre A; Cañizo C; Brunet S; Rosiñol L; Lahuerta J; Díez-Martín J L; León A; García A; Vazquez L; Sierra J; San Miguel J F;
Reduced-intensity conditioning allogeneic transplantation is associated with a high incidence of extramedullary relapses in multiple myeloma patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(3):542-5.
2006: Mateos J; Pérez-Simón J A; Caballero D; Castilla C; Lopez O; Perez E; Cañizo C; Vazquez L; San Miguel J F
Vincristine is an effective therapeutic approach for transplantation-associated thrombotic microangiopathy.
Bone marrow transplantation 2006;37(3):337-8.
2006: Villaron Eva M; Perez-Simon Jose Antonio; San Miguel Jesus F; del Cañizo Consuelo
Bone marrow mesenchymal stem cells chimerism after allogeneic hematopoietic transplantation.
Experimental hematology 2006;34(1):7.
2005: Vazquez L; Mateos J J; Sanz-Rodriguez C; Perez E; Caballero D; San Miguel J F
Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B.
Haematologica 2005;90(12 Suppl):ECR39.
2005: Sarasquete María Eugenia; García-Sanz Ramón; González David; Martínez Joaquín; Mateo Gema; Martínez Pilar; Ribera José Maria; Hernández José Mariano; Lahuerta Juan José; Orfão Alberto; González Marcos; San Miguel Jesus F
Minimal residual disease monitoring in multiple myeloma: a comparison between allelic-specific oligonucleotide real-time quantitative polymerase chain reaction and flow cytometry.
Haematologica 2005;90(10):1365-72.
2005: Fütterer Agnes; Campanero Miguel R; Leonardo Esther; Criado Luis M; Flores Juana M; Hernández Jesús M; San Miguel Jesús F; Martínez-A Carlos
Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms.
The Journal of clinical investigation 2005;115(9):2351-62.
2005: Pérez-Simón José A; Díez-Campelo María; Martino Rodrigo; Brunet Salut; Urbano Alvaro; Caballero María D; de León Angel; Valcárcel David; Carreras Enric; del Cañizo María C; López-Fidalgo Jesús; Sierra Jordi; San Miguel Jesús F
Influence of the intensity of the conditioning regimen on the characteristics of acute and chronic graft-versus-host disease after allogeneic transplantation.
British journal of haematology 2005;130(3):394-403.
2005: Sanchez-Guijo Fermin M; Sanchez-Abarca Luis-Ignacio; Villaron Eva; Lopez-Holgado Natalia; Alberca Mercedes; Vazquez Lourdes; Perez-Simon Jose A; Lopez-Fidalgo Jesus; Orfao Alberto; Caballero Maria-Dolores; Del Cañizo Maria-Consuelo; San Miguel Jesus F
Posttransplant hematopoiesis in patients undergoing sibling allogeneic stem cell transplantation reflects that of their respective donors although with a lower functional capability.
Experimental hematology 2005;33(8):935-43.
2005: González David; González Marcos; Balanzategui Ana; Sarasquete Maria E; López-Pérez Ricardo; Chillón M Carmen; García-Sanz Ramón; San Miguel Jesús F
Molecular characteristics and gene segment usage in IGH gene rearrangements in multiple myeloma.
Haematologica 2005;90(7):906-13.
2005: Sierra Magdalena; Hernández Jesús M; García Juan L; Gutiérrez Norma C; Pérez José J; Vidriales M Belén; Ramos Fernando; Hernández José M; Romero Mercedes; González M Belén; Galende Josefina; San Miguel Jesús F
Hematological, immunophenotypic, and cytogenetic characteristics of acute myeloblastic leukemia with trisomy 11.
Cancer genetics and cytogenetics 2005;160(1):68-72.
2005: Richardson Paul G; Sonneveld Pieter; Schuster Michael W; Irwin David; Stadtmauer Edward A; Facon Thierry; Harousseau Jean-Luc; Ben-Yehuda Dina; Lonial Sagar; Goldschmidt Hartmut; Reece Donna; San-Miguel Jesus F; Bladé Joan; Boccadoro Mario; Cavenagh Jamie; Dalton William S; Boral Anthony L; Esseltine Dixie L; Porter Jane B; Schenkein David; Anderson Kenneth C;
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma.
The New England journal of medicine 2005;352(24):2487-98.
2005: Martino Rodrigo; Pérez-Simón José A; Moreno Estela; Queraltó José M; Caballero Dolores; Mateos Marivi; Sureda Anna; Cañizo Consuelo; Brunet Salut; Briones Javier; Vazquez Lourdes; Clopés Ana; San Miguel Jesús F; Sierra Jorge
Reduced-intensity conditioning allogeneic blood stem cell transplantation with fludarabine and oral busulfan with or without pharmacokinetically targeted busulfan dosing in patients with myeloid leukemia ineligible for conventional conditioning.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(6):437-47.
2005: Hernández J M; Castilla C; Gutiérrez N C; Isidro I M; Delgado M; de las Rivas J; Fermiñán E; García J L; Ocio E M; del Cañizo M C; San Miguel J F
Mobilisation with G-CSF in healthy donors promotes a high but temporal deregulation of genes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(6):1088-91.
2005: Carvajal-Vergara Xonia; Tabera Soraya; Montero Juan C; Esparís-Ogando Azucena; López-Pérez Ricardo; Mateo Gema; Gutiérrez Norma; Parmo-Cabañas Marisa; Teixidó Joaquín; San Miguel Jesús F; Pandiella Atanasio
Multifunctional role of Erk5 in multiple myeloma.
Blood 2005;105(11):4492-9.
2005: Mateo Gema; Castellanos Mariana; Rasillo Ana; Gutiérrez Norma C; Montalbán Ma Angeles; Martín Ma Luisa; Hernández Jesús Ma; López-Berges Ma Consuelo; Montejano Laura; Bladé Joan; Mateos Ma Victoria; Sureda Anna; de la Rubia Javier; Díaz-Mediavilla Joaquín; Pandiella Atanasio; Lahuerta Juan José; Orfao Alberto; San Miguel Jesús F
Genetic abnormalities and patterns of antigenic expression in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3661-7.
2005: Sanchez-Guijo Fermin M; Sanchez-Abarca Luis-Ignacio; Bueno Clara; Villaron Eva; Lopez-Holgado Natalia; Vazquez Lourdes; Lopez-Fidalgo Jesus; Perez-Simon Jose A; Caballero Maria-Dolores; del Cañizo Maria-Consuelo; Orfao Alberto; San Miguel Jesus F
Long-term immune recovery of patients undergoing allogeneic stem cell transplantation: a comparison with their respective sibling donors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(5):354-61.
2005: Primo D; Tabernero M D; Perez J J; Rasillo A; Sayagués J M; Espinosa A B; Lopez-Berges M C; García-Sanz R; Gutierrez N C; Hernandez J M; Romero M; Osuna C S; Giralt M; Barbon M; San Miguel J F; Orfao A
Genetic heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disease characteristics.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(5):713-20.
2005: Ocio Enrique M; Sanchez-Guijo Fermin M; Diez-Campelo Maria; Castilla Cristina; Blanco Oscar J; Caballero Dolores; San Miguel Jesus F
Efficacy of rituximab in an aggressive form of multicentric Castleman disease associated with immune phenomena.
American journal of hematology 2005;78(4):302-5.
2005: Esparís-Ogando Azucena; Alegre Adrián; Aguado Beatriz; Mateo Gema; Gutiérrez Norma; Bladé Joan; Schenkein David; Pandiella Atanasio; San Miguel Jesús F
Bortezomib is an efficient agent in plasma cell leukemias.
International journal of cancer. Journal international du cancer 2005;114(4):665-7.
2005: Ocio Enrique M; Mateo Gema; Vidriales Belen; Lopez-Berges M Consuelo; Garcia-Sanz Ramon; Hernandez Jesus M; Orfao Alberto; San Miguel Jesus F
Cell cycle analysis of Waldenstrom's macroglobulinemia.
Clinical lymphoma 2005;5(4):250-2.
2005: Ocio Enrique M; Hernandez Jesus M; Mateo Gema; Sanchez Maria L; Gonzalez Belen; Vidriales Belen; Gutierrez Norma C; Orfao Alberto; San Miguel Jesus F
Immunophenotypic and cytogenetic comparison of Waldenstrom's macroglobulinemia with splenic marginal zone lymphoma.
Clinical lymphoma 2005;5(4):241-5.
2005: López-Holgado Natalia; Pata Carmen; Villarón Eva; Sánchez-Guijo Fermín; Alberca Mercedes; Martín Alejandro; Corral Mercedes; Sánchez-Abarca Ignacio; Pérez-Simón Josè Antonio; San Miguel Jesús Fernando; del Cañizo Maria Consuelo
Long-term bone marrow culture data are the most powerful predictor of peripheral blood progenitor cell mobilization in healthy donors.
Haematologica 2005;90(3):353-9.
2005: Pérez-Andrés M; Almeida J; Martín-Ayuso M; Moro M J; Martín-Nuñez G; Galende J; Borrego D; Rodríguez M J; Ortega F; Hernandez J; Moreno I; Domínguez M; Mateo G; San Miguel J F; Orfao A;
Clonal plasma cells from monoclonal gammopathy of undetermined significance, multiple myeloma and plasma cell leukemia show different expression profiles of molecules involved in the interaction with the immunological bone marrow microenvironment.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(3):449-55.
2005: Gutiérrez N C; López-Pérez R; Hernández J M; Isidro I; González B; Delgado M; Fermiñán E; García J L; Vázquez L; González M; San Miguel J F
Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(3):402-9.
2005: Díez-Campelo M; Pérez-Simón J A; Ocio E M; Castilla C; González-Porras J R; Sánchez-Guijo F M; Vázquez L; Caballero M D; Cañizo M C; San Miguel J F
CD34 + cell dose and outcome of patients undergoing reduced-intensity-conditioning allogeneic peripheral blood stem cell transplantation.
Leukemia & lymphoma 2005;46(2):177-83.
2005: Martín Alejandro; Pérez-Simón Josè Antonio; Caballero Maria Dolores; López-Holgado Natalia; Vázquez Lourdes; del Cañizo Maria Consuelo; San Miguel Jesus F
Effect of pre-transplant cumulative doses of chemotherapeutic drugs on early and long-term hematological recovery after autologous bone-marrow transplantation for lymphoma.
Haematologica 2005;90(1):78-85.
2005: Suárez Lilia; Vidriales María Belén; Moreno María-José; López Antonio; García-Laraña José; Pérez-López Cristina; Tormo Mar; Lavilla Esperanza; López-Berges María Consuelo; de Santiago María; San Miguel Jesús F; Orfao Alberto;
Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells.
Haematologica 2005;90(1):54-9.
2005: San Miguel Jesús F; García-Sanz Ramón
Prognostic features of multiple myeloma.
Best practice & research. Clinical haematology 2005;18(4):569-83.
2004: Villaron Eva María; Almeida Julia; López-Holgado Natalia; Alcoceba Miguel; Sánchez-Abarca Luis Ignacio; Sanchez-Guijo Fermin Martin; Alberca Mercedes; Pérez-Simon Jose Antonio; San Miguel Jesus Fernando; Del Cañizo María Consuelo
Mesenchymal stem cells are present in peripheral blood and can engraft after allogeneic hematopoietic stem cell transplantation.
Haematologica 2004;89(12):1421-7.
2004: García-Sanz R; González-Fraile M I; Mateo G; Hernández J M; López-Berges M C; de las Heras N; Fernández-Calvo J; Ortega F; Portero J A; Bárez A; Galende J; Orfão A; San Miguel J F
Proliferative activity of plasma cells is the most relevant prognostic factor in elderly multiple myeloma patients.
International journal of cancer. Journal international du cancer 2004;112(5):884-9.
2004: López-Holgado Natalia; Arroyo Jose Luis; Pata Carmen; Villarón Eva; Sánchez Guijo Fermín; Martín Alejandro; Hernández Rivas Jesús María; Orfao Alberto; San Miguel Jesús Fernando; Del Cañizo Fernández-Roldán M Consuelo
Analysis of hematopoietic progenitor cells in patients with myelodysplastic syndromes according to their cytogenetic abnormalities.
Leukemia research 2004;28(11):1181-7.
2004: Gutiérrez Norma C; García Juan L; Hernández Jesús M; Lumbreras Eva; Castellanos Mariana; Rasillo Ana; Mateo Gema; Hernández José M; Pérez Sonia; Orfao Alberto; San Miguel Jesús F
Prognostic and biologic significance of chromosomal imbalances assessed by comparative genomic hybridization in multiple myeloma.
Blood 2004;104(9):2661-6.
2004: González M Belén; Hernández Jesús M; García Juan L; Lumbreras Eva; Castellanos Mariana; Hernández José M; Fernández-Calvo Javier; Gutiérrez Norma C; San Miguel Jesús F
The value of fluorescence in situ hybridization for the detection of 11q in multiple myeloma.
Haematologica 2004;89(10):1213-8.
2004: Hernández J M; García-Sanz R; Golvano E; Bladé J; Fernandez-Calvo J; Trujillo J; Soler J A; Gardella S; Carbonell F; Mateo G; San Miguel J F
Randomized comparison of dexamethasone combined with melphalan versus melphalan with prednisone in the treatment of elderly patients with multiple myeloma.
British journal of haematology 2004;127(2):159-64.
2004: Kröger Nicolaus; Perez-Simon Jose A; Myint Han; Klingemann Hans; Shimoni Avichai; Nagler Arnon; Martino Rodrigo; Alegre Adrian; Tomas Jose F; Schwerdtfeger Rainer; Kiehl Michael; Fauser Axel; Sayer Herbert Gottfried; Leon Angel; Beyer Jörg; Zabelina Tatjana; Ayuk Francis; San Miguel Jesus F; Brand Ronald; Zander Axel Rolf
Relapse to prior autograft and chronic graft-versus-host disease are the strongest prognostic factors for outcome of melphalan/fludarabine-based dose-reduced allogeneic stem cell transplantation in patients with multiple myeloma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(10):698-708.
2004: Pérez-Simón J A; Caballero D; Mateos M V; San Miguel J F
Graft vs. host disease and graft vs. myeloma effect after non-myeloablative allogeneic transplantation.
Leukemia & lymphoma 2004;45(9):1725-9.
2004: Pérez-Andrés M; Santiago M; Almeida J; Mateo G; Porwit-MacDonald A; Bjorklund E; Valet G; Kraan J; Gratama J W; D'Hautcourt J L; Merle-Beral H; Lima M; Montalban M A; San Miguel J F; Orfao I;
Immunophenotypic approach to the identification and characterization of clonal plasma cells from patients with monoclonal gammopathies.
Journal of biological regulators and homeostatic agents 2004;18(3-4):392-8.
2004: Suárez L; Vidriales M B; Sanz G; López A; López-Berges M C; de Santiago M; Palomera L; Bernal T; Pérez de Equiza M E; San Miguel J F; Orfao A
Expression of APO2.7, bcl-2 and bax apoptosis-associated proteins in CD34- bone marrow cell compartments from patients with myelodysplastic syndromes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(7):1311-3.
2004: Kröger Nicolaus; Schilling Georgia; Einsele Hermann; Liebisch Peter; Shimoni Avichai; Nagler Arnon; Perez-Simon Jose A; San Miguel Jesus F; Kiehl Michael; Fauser Axel; Schwerdtfeger Rainer; Wandt Hannes; Sayer Herbert G; Myint Han; Klingemann Hans; Zabelina Tatjana; Dierlamm Judith; Hinke Axel; Zander Axel R
Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation.
Blood 2004;103(11):4056-61.
2004: Perez-Andres M; Almeida J; Martin-Ayuso M; Moro M J; Garcia-Marcos M A; Moreno I; Dominguez M; Galende J; Heras N; Gonzalez M I; San Miguel J F; Orfao A;
Interaction between clonal plasma cells and the immune system in plasma cell dyscrasias.
Journal of biological regulators and homeostatic agents 2004;18(2):161-5.
2004: González M Belén; Gutiérrez Norma C; García Juan L; Schoenmakers Eric F P M; Solé Francesc; Calasanz M José; San Miguel Jesús F; Hernández Jesús M
Heterogeneity of structural abnormalities in the 7q31.3 approximately q34 region in myeloid malignancies.
Cancer genetics and cytogenetics 2004;150(2):136-43.
2004: García-Sanz R; González-Porras J R; Hernández J M; Polo-Zarzuela M; Sureda A; Barrenetxea C; Palomera L; López R; Grande-García C; Alegre A; Vargas-Pabón M; Gutiérrez O N; Rodríguez J A; San Miguel J F
The oral combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is effective in relapsed/refractory multiple myeloma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(4):856-63.
2004: Martín A; Pérez-Simón J-A; Caballero M D; López N; García-Sanz R; Vázquez L; del Cañizo M C; San Miguel J F
Effect of cumulative etoposide doses on the outcome of autologous peripheral-blood progenitor-cell transplantation for lymphoma.
Bone marrow transplantation 2004;33(6):579-87.
2004: Menendez P; Vargas A; Bueno C; Barrena S; Almeida J; De Santiago M; López A; Roa S; San Miguel J F; Orfao A
Quantitative analysis of bcl-2 expression in normal and leukemic human B-cell differentiation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(3):491-8.
2004: Bueno Clara; Almeida Julia; Lucio Paulo; Marco Josefa; Garcia Raimundo; de Pablos Jose Maria; Parreira Antonio; Ramos Fernando; Ruiz-Cabello Francisco; Suarez-Vilela Dimas; San Miguel Jesus F; Orfao Alberto
Incidence and characteristics of CD4(+)/HLA DRhi dendritic cell malignancies.
Haematologica 2004;89(1):58-69.
2004: Pérez-Simón J A; García-Escobar I; Martinez J; Vazquez L; Caballero D; Cañizo C; Mateos M V; San Miguel J F
Antibiotic prophylaxis with meropenem after allogeneic stem cell transplantation.
Bone marrow transplantation 2004;33(2):183-7.
2004: Hernández José M; Suquía Begoña; Queizan José A; Fisac Rosa M; Sanchez José J; Fernández-Calvo Francisco J; García-Sanz Ramón; Olivier Carmen; Bárez Abelardo; Calmuntia María J; García-Frade Javier; Portero Juan A; López Rosa; Aguilera Carmen; Navajo Jose A; San-Miguel Jesús F
Bone remodelation markers are useful in the management of monoclonal gammopathies.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(6):480-8.
2004: Arroyo Jose Luis; Fernández Ma Eugenia; Hernández Jesús Maria; Orfao Alberto; San Miguel Jesús Fernando; del Cañizo Maria Consuelo
Impact of immunophenotype on prognosis of patients with myelodysplastic syndromes. Its value in patients without karyotypic abnormalities.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(3):227-33.
2003: Rodriguez José; Caballero Maria Dolores; Gutierrez Antonio; Gandarillas Marco; Sierra Jorge; Lopez-Guillermo Armando; Sureda Anna; Zuazu Javier; Marin Jesus; Arranz Reyes; Carreras Enric; Leon Angel; De Sevilla Alberto Fernández; San Miguel Jesus F; Conde Eulogio;
High dose chemotherapy and autologous stem cell transplantation in patients with peripheral T-cell lymphoma not achieving complete response after induction chemotherapy. The GEL-TAMO experience.
Haematologica 2003;88(12):1372-7.
2003: Pandiella Atanasio; Carvajal-Vergara Xonia; Tabera Soraya; Mateo Gema; Gutiérrez Norma; San Miguel Jesús F
Imatinib mesylate (STI571) inhibits multiple myeloma cell proliferation and potentiates the effect of common antimyeloma agents.
British journal of haematology 2003;123(5):858-68.
2003: Vidriales María B; San-Miguel Jesús F; Orfao Alberto; Coustan-Smith Elaine; Campana Dario
Minimal residual disease monitoring by flow cytometry.
Best practice & research. Clinical haematology 2003;16(4):599-612.
2003: García J L; Hernandez J M; Gutiérrez N C; Flores T; González D; Calasanz M J; Martínez-Climent J A; Piris M A; Lopéz-Capitán C; González M B; Odero M D; San Miguel J F
Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(10):2016-24.
2003: Garcia Juan L; Font de Mora Jaime; Hernandez Jesus M; Queizan Jose A; Gutierrez Norma C; Hernandez Jose M; San Miguel Jesus F
Imatinib mesylate elicits positive clinical response in atypical chronic myeloid leukemia involving the platelet-derived growth factor receptor beta.
Blood 2003;102(7):2699-700.
2003: Sanchez Maria-Luz; Almeida Julia; Gonzalez David; Gonzalez Marcos; Garcia-Marcos Maria-Antonia; Balanzategui Ana; Lopez-Berges Maria-Consuelo; Nomdedeu Josep; Vallespi Teresa; Barbon Marcos; Martin Alejandro; de la Fuente Pilar; Martin-Nuñez Guillermo; Fernandez-Calvo Javier; Hernandez Jesus-Maria; San Miguel Jesus F; Orfao Alberto
Incidence and clinicobiologic characteristics of leukemic B-cell chronic lymphoproliferative disorders with more than one B-cell clone.
Blood 2003;102(8):2994-3002.
2003: Mateo Gema; Corral Mercedes; Almeida Julia; López-Berges Consuelo; Nieto maría Jesús; García-Marcos Antonia; Vázquez Lourdes; del Cañizo Consuelo; Orfao Alberto; San Miguel Jesús F
Immunophenotypic analysis of peripheral blood stem cell harvests from patients with multiple myeloma.
Haematologica 2003;88(9):1013-21.
2003: Vidriales María-Belén; Orfao Alberto; San-Miguel Jesús F
Immunologic monitoring in adults with acute lymphoblastic leukemia.
Current oncology reports 2003;5(5):413-8.
2003: Lima Margarida; Almeida Julia; Dos Anjos Teixeira Maria; Alguero Md Maria del Carmen; Santos Ana Helena; Balanzategui Ana; Queirós Maria Luís; Bárcena Paloma; Izarra Antonio; Fonseca Sónia; Bueno Clara; Justiça Benvindo; Gonzalez Marcos; San Miguel Jesús F; Orfao Alberto
TCRalphabeta+/CD4+ large granular lymphocytosis: a new clonal T-cell lymphoproliferative disorder.
The American journal of pathology 2003;163(2):763-71.
2003: Primo D; Tabernero M D; Rasillo A; Sayagués J M; Espinosa A B; Chillón M C; Garcia-Sanz R; Gutierrez N; Giralt M; Hagemeijer A; San Miguel J F; Orfao A
Patterns of BCR/ABL gene rearrangements by interphase fluorescence in situ hybridization (FISH) in BCR/ABL+ leukemias: incidence and underlying genetic abnormalities.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(6):1124-9.
2003: González D; González M; Alonso M E; López-Pérez R; Balanzategui A; Chillón M C; Silva M; García-Sanz R; San Miguel J F
Incomplete DJH rearrangements as a novel tumor target for minimal residual disease quantitation in multiple myeloma using real-time PCR.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(6):1051-7.
2003: San Miguel Jesús F; García-Sanz Ramón
Myeloma: update on supportive care strategies.
Current treatment options in oncology 2003;4(3):247-58.
2003: Vidriales María-Belén; Pérez José J; López-Berges Maria Consuelo; Gutiérrez Norma; Ciudad Juana; Lucio Paulo; Vazquez Lourdes; García-Sanz Ramón; del Cañizo Maria Consuelo; Fernández-Calvo Javier; Ramos Fernando; Rodríguez M Jesús; Calmuntia M José; Porwith Ana; Orfao Alberto; San-Miguel Jesús F
Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: early immunophenotypic evaluation has high clinical value.
Blood 2003;101(12):4695-700.
2003: San Miguel J F; Vidriales M B; Ocio E; Mateo G; Sánchez-Guijo F; Sánchez M L; Escribano L; Bárez A; Moro M J; Hernández J; Aguilera C; Cuello R; García-Frade J; López R; Portero J; Orfao A
Immunophenotypic analysis of Waldenstrom's macroglobulinemia.
Seminars in oncology 2003;30(2):187-95.
2003: Owen Roger G; Treon Steven P; Al-Katib Ayad; Fonseca Rafael; Greipp Philip R; McMaster Mary L; Morra Enrica; Pangalis Gerassimos A; San Miguel Jesus F; Branagan Andrew R; Dimopoulos Meletios A
Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia.
Seminars in oncology 2003;30(2):110-5.
2003: Del Cañizo M Consuelo; Fernández M Eugenia; López Antonio; Vidriales Belén; Villarón Eva; Arroyo José L; Ortuño Francisco; Orfao Alberto; San Miguel Jesus F
Immunophenotypic analysis of myelodysplastic syndromes.
Haematologica 2003;88(4):402-7.
2003: Pérez-Simón José A; Martino Rodrigo; Alegre Adrián; Tomás José F; De Leon Angel; Caballero Dolores; Sureda Ana; Sierra Jordi; San Miguel Jesús F
Chronic but not acute graft-versus-host disease improves outcome in multiple myeloma patients after non-myeloablative allogeneic transplantation.
British journal of haematology 2003;121(1):104-8.
2003: Valcárcel D; Martino R; Caballero D; Mateos M V; Pérez-Simón J A; Canals C; Fernández F; Bargay J; Muñiz-Díaz E; Gonzalez M; San Miguel J F; Sierra J
Chimerism analysis following allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning.
Bone marrow transplantation 2003;31(5):387-92.
2003: Rasillo Ana; Tabernero María Dolores; Sánchez María Luz; Pérez de Andrés Martín; Martín Ayuso Marta; Hernández José; Moro María Jesús; Fernández-Calvo Javier; Sayagués José María; Bortoluci Aglae; San Miguel Jesús Fernando; Orfao Alberto
Fluorescence in situ hybridization analysis of aneuploidization patterns in monoclonal gammopathy of undetermined significance versus multiple myeloma and plasma cell leukemia.
Cancer 2003;97(3):601-9.
2003: Caballero M D; Pérez-Simón J A; Iriondo A; Lahuerta J J; Sierra J; Marín J; Gandarillas M; Arranz R; Zuazu J; Rubio V; Fernández de Sevilla A; Carreras E; García-Conde J; García-Laraña J; Grande C; Sureda A; Vidal M J; Rifón J; Pérez-Equiza C; Varela R; Moraleda J M; García Ruíz J C; Albó C; Cabrera R; San Miguel J F; Conde E
High-dose therapy in diffuse large cell lymphoma: results and prognostic factors in 452 patients from the GEL-TAMO Spanish Cooperative Group.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(1):140-51.
2003: Gutiérrez Norma C; Camps Jordi; Hernández Jesús M; García Juan L; Prat Esther; González M Belén; Miró Rosa; San Miguel Jesús F
Multicolor fluorescence in situ hybridization studies in multiple myeloma and monoclonal gammopathy of undetermined significance.
The hematology journal : the official journal of the European Haematology Association / EHA 2003;4(1):67-70.
2002: González-Porras J R; González M; García-Sanz R; San Miguel J F
Thalidomide in combination with cyclophosphamide and dexamethasone (thacydex) is effective in soft-tissue plasmacytomas.
British journal of haematology 2002;119(3):883-4.
2002: Pérez-Simón José A; Kottaridis Panagiotis D; Martino Rodrigo; Craddock Charles; Caballero Dolores; Chopra Raj; García-Conde Javier; Milligan Don W; Schey Stephen; Urbano-Ispizua Alvaro; Parker Anne; Leon Angel; Yong Kwee; Sureda Ana; Hunter Ann; Sierra Jordi; Goldstone Anthony H; Linch David C; San Miguel Jesus F; Mackinnon Stephen;
Nonmyeloablative transplantation with or without alemtuzumab: comparison between 2 prospective studies in patients with lymphoproliferative disorders.
Blood 2002;100(9):3121-7.
2002: Menéndez Pablo; Pérez-Simón Jose A; Mateos Maria V; Caballero Maria D; González Marcos; San-Miguel Jesus F; Orfao Alberto
Influence of the different CD34+ and CD34- cell subsets infused on clinical outcome after non-myeloablative allogeneic peripheral blood transplantation from human leucocyte antigen-identical sibling donors.
British journal of haematology 2002;119(1):135-43.
2002: Menéndez Pablo; Caballero Maria D; Prosper Felipe; Del Cañizo Maria C; Pérez-Simón Jose A; Mateos Maria V; Nieto Maria J; Corral Mercedes; Romero Mercedes; García-Conde Javier; Montalbán Maria A; San Miguel Jesus F; Orfao Alberto
The composition of leukapheresis products impacts on the hematopoietic recovery after autologous transplantation independently of the mobilization regimen.
Transfusion 2002;42(9):1159-72.
2002: Mateos Maria V; García-Sanz Ramón; López-Pérez Ricardo; Moro Maria J; Ocio Enrique; Hernández Jose; Megido Marta; Caballero Maria D; Fernández-Calvo Javier; Bárez Abelardo; Almeida Julia; Orfão Alberto; González Marcos; San Miguel Jesús F
Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival.
British journal of haematology 2002;118(4):1034-40.
2002: Martino Rodrigo; Perea Granada; Caballero María Dolores; Mateos María V; Ribera Josep M; de Oteyza Jaime Pérez; Arranz Reyes; Terol María José; Sierra Jorge; San Miguel Jesús F
Cyclophosphamide, pegylated liposomal doxorubicin (Caelyx), vincristine and prednisone (CCOP) in elderly patients with diffuse large B-cell lymphoma: results from a prospective phase II study.
Haematologica 2002;87(8):822-7.
2002: Sánchez M L; Almeida J; Vidriales B; López-Berges M C; García-Marcos M A; Moro M J; Corrales A; Calmuntia M J; San Miguel J F; Orfao A
Incidence of phenotypic aberrations in a series of 467 patients with B chronic lymphoproliferative disorders: basis for the design of specific four-color stainings to be used for minimal residual disease investigation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(8):1460-9.
2002: Pérez-Simón J A; Caballero D; Diez-Campelo M; Lopez-Pérez R; Mateos G; Cañizo C; Vazquez L; Vidriales B; Mateos M V; Gonzalez M; San Miguel J F
Chimerism and minimal residual disease monitoring after reduced intensity conditioning (RIC) allogeneic transplantation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(8):1423-31.
2002: Martín Alejandro; García-Sanz Ramón; Hernández José; Bladé Joan; Suquía Begoña; Fernández-Calvo Javier; González Marcos; Mateo Gema; Orfao Alberto; San Miguel Jesus F
Pamidronate induces bone formation in patients with smouldering or indolent myeloma, with no significant anti-tumour effect.
British journal of haematology 2002;118(1):239-42.
2002: González-Fraile Maria I; García-Sanz Ramon; Mateos Maria V; Balanzategui Ana; González Marcos; Váquez Lourdes; San Miguel Jesús F
Methylenetetrahydrofolate reductase genotype does not play a role in multiple myeloma pathogenesis.
British journal of haematology 2002;117(4):890-2.
2002: San-Miguel Jesús F; Vidriales María B; Orfão Alberto
Immunological evaluation of minimal residual disease (MRD) in acute myeloid leukaemia (AML).
Best practice & research. Clinical haematology 2002;15(1):105-18.
2002: San Miguel Jesús F; Almeida Julia; Mateo Gema; Bladé Joan; López-Berges Consuelo; Caballero Dolores; Hernández José; Moro María Jesús; Fernández-Calvo Javier; Díaz-Mediavilla Joaquín; Palomera Luis; Orfao Alberto
Immunophenotypic evaluation of the plasma cell compartment in multiple myeloma: a tool for comparing the efficacy of different treatment strategies and predicting outcome.
Blood 2002;99(5):1853-6.
2002: Ribera Josep-Maria; Ortega Juan-José; Oriol Albert; Granada Isabel; Hernández-Rivas Jesús-Maria; Parody Ricardo; Bethencourt Concepción; Rivas Concepción; Bastida Pilar; del Potro Eloy; González-Valentín Maria-Elvira; Moreno María-José; Besalduch Joan; Fernández-Calvo Javier; Tormo Mar; Arias Jesús; Molinés Antonio; Sanz Miguel Angel; Maldonado Juan; Millá Fuensanta; Feliu Evarist; San Miguel Jesús-Fernando;
Prognostic value of karyotypic analysis in children and adults with high-risk acute lymphoblastic leukemia included in the PETHEMA ALL-93 trial.
Haematologica 2002;87(2):154-66.
2002: García-Sanz Ramón; González-Fraile Maria Isabel; Sierra Magdalena; López Carlos; González Marcos; San Miguel Jesús Fernando
The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma.
The hematology journal : the official journal of the European Haematology Association / EHA 2002;3(1):43-8.
2001: González M; López-Pérez R; García-Sanz R; Pérez-Simón J A; San Miguel J F
Debate round-table: comments concerning chimerism studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(12):1986-8.
2001: Suárez L; Vidriales B; García-Laraña J; López A; Martínez R; Martín-Reina V; Tormo M; González-San Miguel J D; Lavilla E; García-Boyero R; Orfao A; San Miguel J F;
Multiparametric analysis of apoptotic and multi-drug resistance phenotypes according to the blast cell maturation stage in elderly patients with acute myeloid leukemia.
Haematologica 2001;86(12):1287-95.
2001: Lima M; Almeida J; Santos A H; dos Anjos Teixeira M; Alguero M C; Queirós M L; Balanzategui A; Justiça B; Gonzalez M; San Miguel J F; Orfão A
Immunophenotypic analysis of the TCR-Vbeta repertoire in 98 persistent expansions of CD3(+)/TCR-alphabeta(+) large granular lymphocytes: utility in assessing clonality and insights into the pathogenesis of the disease.
The American journal of pathology 2001;159(5):1861-8.
2001: López-Pérez R; García-Sanz R; González D; Balanzategui A; Chillón M C; Alaejos I; Mateos M V; Caballero M D; Corral M; Orfão A; González M; San Miguel J F
Gene scanning of VDJH-amplified segments is a clinically relevant technique to detect contaminating tumor cells in the apheresis products of multiple myeloma patients undergoing autologous peripheral blood stem cell transplantation.
Bone marrow transplantation 2001;28(7):665-72.
2001: Arroyo J L; García-Marcos M A; López A; Menéndez P; Tabernero M D; Sánchez-Abarca L I; Avila-Zarza C; San Miguel J F; Orfao A
Evaluation of a CD61 MoAb method for enumeration of platelets in thrombocytopenic patients and its impact on the transfusion decision-making process.
Transfusion 2001;41(10):1212-6.
2001: San Miguel J F; Vidriales M B; López-Berges C; Díaz-Mediavilla J; Gutiérrez N; Cañizo C; Ramos F; Calmuntia M J; Pérez J J; González M; Orfao A
Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to postinduction treatment stratification.
Blood 2001;98(6):1746-51.
2001: Lucio P; Gaipa G; van Lochem E G; van Wering E R; Porwit-MacDonald A; Faria T; Bjorklund E; Biondi A; van den Beemd M W; Baars E; Vidriales B; Parreira A; van Dongen J J; San Miguel J F; Orfao A;
BIOMED-I concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings. BIOMED-1 Concerted Action Investigation of Minimal Residual Disease in Acute Leukemia: International Standardization and Clinical Evaluation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(8):1185-92.
2001: Ortega J J; Ribera J M; Oriol A; Bastida P; González M E; Calvo C; Egurbide I; Hernández Rivas J M; Rivas C; Alcalá A; Besalduch J; Maciá J; Gardella S; Carnero M; Lite J M; Casanova F; Martinez M; Fontanillas M; Feliu E; San Miguel J F;
Early and delayed consolidation chemotherapy significantly improves the outcome of children with intermediate risk acute lymphoblastic leukemia. Final results of the prospective randomized PETHEMA ALL-89 TRIAL.
Haematologica 2001;86(6):586-95.
2001: Canales M A; Fernández-Jiménez M C; Martín A; Arrieta R; Caballero M D; Díez J; Quevedo E; García-Bustos J; San Miguel J F; Hernández-Navarro F
Identification of factors associated with poor peripheral blood progenitor cell mobilization in Hodgkin's disease.
Haematologica 2001;86(5):494-8.
2001: Gutiérrez N C; Hernández J M; García J L; Cañizo M C; González M; Hernández J; González M B; Garciá-Marcos M A; San Miguel J F
Differences in genetic changes between multiple myeloma and plasma cell leukemia demonstrated by comparative genomic hybridization.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(5):840-5.
2001: Hernández J M; García J L; Gutiérrez N C; Mollejo M; Martínez-Climent J A; Flores T; González M B; Piris M A; San Miguel J F
Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.
The American journal of pathology 2001;158(5):1843-50.
2001: Martín A; Fernández-Jiménez M C; Caballero M D; Canales M A; Pérez-Simón J A; García de Bustos J; Vázquez L; Hernández-Navarro F; San Miguel J F
Long-term follow-up in patients treated with Mini-BEAM as salvage therapy for relapsed or refractory Hodgkin's disease.
British journal of haematology 2001;113(1):161-71.
2001: González-Fraile M I; Cañizo C; Caballero D; Hernández R; Vázquez L; López C; Izarra A; Arroyo J L; de la Loma A; Otero M J; San Miguel J F
Cidofovir treatment of human polyomavirus-associated acute haemorrhagic cystitis.
Transplant infectious disease : an official journal of the Transplantation Society 2001;3(1):44-6.
2001: Menéndez P; Prósper F; Bueno C; Arbona C; San Miguel J F; García-Conde J; Solá C; Hornedo J; Cortés-Funes H; Orfao A
Sequential analysis of CD34+ and CD34- cell subsets in peripheral blood and leukapheresis products from breast cancer patients mobilized with SCF plus G-CSF and cyclophosphamide.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(3):430-9.
2001: Tabernero M D; Bortoluci A M; Alaejos I; López-Berges M C; Rasillo A; García-Sanz R; García M; Sayagués J M; González M; Mateo G; San Miguel J F; Orfao A
Adult precursor B-ALL with BCR/ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10, CD34, CD13 and CD38 expresssion.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(3):406-14.
2001: Bueno C; Almeida J; Alguero M C; Sánchez M L; Vaquero J M; Laso F J; San Miguel J F; Escribano L; Orfao A
Flow cytometric analysis of cytokine production by normal human peripheral blood dendritic cells and monocytes: comparative analysis of different stimuli, secretion-blocking agents and incubation periods.
Cytometry 2001;46(1):33-40.
2001: Chillón C M; García-Sanz R; Balanzategui A; Ramos F; Fernández-Calvo J; Rodríguez M J; Rodríguez-Salazar M I; Corrales A; Calmuntia M J; Orfão A; González M; San Miguel J F
Molecular characterization of acute myeloblastic leukemia according to the new WHO classification: a different distribution in Central-West Spain.
Haematologica 2001;86(2):162-6.
2001: Bladé J; San Miguel J F; Fontanillas M; Esteve J; Maldonado J; Alcalá A; Brunet S; García-Conde J; Besalduch J; Moro M J; Fernández-Calvo J; Conde E; Font L; Gardella S; Carnero M; Carbonell F; Martí J M; Hernández-Martín J; Ortega F; Besses C; Ribera J M; Trujillo J; Escudero M L; Rozman C; Estapé J; Montserrat E
Increased conventional chemotherapy does not improve survival in multiple myeloma: long-term results of two PETHEMA trials including 914 patients.
The hematology journal : the official journal of the European Haematology Association / EHA 2001;2(4):272-8.
2001: Mateos M V; Garcia-Sanz R; López-Pérez R; Balanzategui A; González M I; Fernández-Calvo J; Moro M J; Hernández J; Caballero M D; González M; San Miguel J F
p16/INK4a gene inactivation by hypermethylation is associated with aggressive variants of monoclonal gammopathies.
The hematology journal : the official journal of the European Haematology Association / EHA 2001;2(3):146-9.
2000: Arroyo J L; Gutierrez N C; García-Marcos M A; Villarroel R; Galindo P; Fernández M E; Izarra A; del Cañizo M C; Caballero M D; San Miguel J F
Monocyte counts: an early index of haemopoietic reconstitution after peripheral blood stem cell transplantation.
British journal of haematology 2000;111(3):987-9.
2000: Hernández R; del Cañizo M C; López C; González M I; Vázquez M L; Caballero M D; San Miguel J F
Pathologic rupture of the spleen during induction with ATRA in a patient with acute promyelocytic leukemia.
Medical oncology (Northwood, London, England) 2000;17(4):337-9.
2000: Gutiérrez N C; Hernández J M; García J L; Almeida J; Mateo G; González M I; Hernández J; Fernández-Calvo J; San Miguel J F
Correlation between cytogenetic abnormalities and disease characteristics in multiple myeloma: monosomy of chromosome 13 and structural abnormalities of 11q are associated with a high percentage of S-phase plasma cells.
Haematologica 2000;85(11):1146-52.
2000: González M I; Caballero D; López C; Alburquerque T; Hernández R; de la Loma A; Cañizo C; Vázquez L; San Miguel J F
Cerebral toxoplasmosis and Guillain-Barré syndrome after allogeneic peripheral stem cell transplantation.
Transplant infectious disease : an official journal of the Transplantation Society 2000;2(3):145-9.
2000: López-Pérez R; García-Sanz R; González D; Balanzategui A; Chillón M C; Alaejos I; Mateos M V; Caballero M D; Mateo G; Nieto M J; González M; San Miguel J F
The detection of contaminating clonal cells in apheresis products is related to response and outcome in multiple myeloma undergoing autologous peripheral blood stem cell transplantation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(8):1493-9.
2000: Mateos M V; González M; Balanzategui A; López-Pérez R; González D; Chillón M C; Alaejos I; García-Sanz R; San Miguel J F
Status of methylation of p16 gene in multiple myeloma: a comparative study of three methods for its detection.
Clinical biochemistry 2000;33(5):415-8.
2000: González M I; Caballero D; Vázquez L; Cañizo C; Hernández R; López C; Izarra A; Arroyo J L; González M; García R; San Miguel J F
Allogeneic peripheral stem cell transplantation in a case of hereditary sideroblastic anaemia.
British journal of haematology 2000;109(3):658-60.
2000: Porwit-MacDonald A; Björklund E; Lucio P; van Lochem E G; Mazur J; Parreira A; van den Beemd M W; van Wering E R; Baars E; Gaipa G; Biondi A; Ciudad J; van Dongen J J; San Miguel J F; Orfao A
BIOMED-1 concerted action report: flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(5):816-25.
2000: Hernández J M; del Cañizo M C; Cuneo A; García J L; Gutiérrez N C; González M; Castoldi G; San Miguel J F
Clinical, hematological and cytogenetic characteristics of atypical chronic myeloid leukemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(4):441-4.
2000: Vazquez L; Caballero D; Cañizo C D; Lopez C; Hernandez R; Gonzalez I; Flores T; San Miguel J F
Allogeneic peripheral blood cell transplantation for hypereosinophilic syndrome with myelofibrosis.
Bone marrow transplantation 2000;25(2):217-8.
2000: González M; Mateos M V; García-Sanz R; Balanzategui A; López-Pérez R; Chillón M C; González D; Alaejos I; San Miguel J F
De novo methylation of tumor suppressor gene p16/INK4a is a frequent finding in multiple myeloma patients at diagnosis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(1):183-7.
2000: Hernández J M; González M B; García J L; Ferro M T; Gutiérrez N C; Marynen P; San Miguel J F
Two cases of myeloid disorders and a t(8;12) (q12;p13).
Haematologica 2000;85(1):31-4.
1999: San Miguel J F; Ciudad J; Vidriales M B; Orfao A; Lucio P; Porwit-MacDonald A; Gaipa G; van Wering E; van Dongen J J
Immunophenotypical detection of minimal residual disease in acute leukemia.
Critical reviews in oncology/hematology 1999;32(3):175-85.
1999: Pérez-Simón J A; Martín A; Caballero D; Corral M; Nieto M J; Gonzalez M; Vazquez L; López-Berges C; Cañizo M C; Mateos M V; Orfao A; San Miguel J F
Clinical significance of CD34+ cell dose in long-term engraftment following autologous peripheral blood stem cell transplantation.
Bone marrow transplantation 1999;24(12):1279-83.
1999: del Cañizo C; Galende J; Almeida J; Brufau A; Mota A; San Miguel J F
In vitro growth in acute myeloblastic leukemia: clinico-biological correlations.
Leukemia & lymphoma 1999;36(1-2):1-7.
1999: Almeida J; Bueno C; Alguero M C; Sanchez M L; Cañizo M C; Fernandez M E; Vaquero J M; Laso F J; Escribano L; San Miguel J F; Orfao A
Extensive characterization of the immunophenotype and pattern of cytokine production by distinct subpopulations of normal human peripheral blood MHC II+/lineage- cells.
Clinical and experimental immunology 1999;118(3):392-401.
1999: García-Sanz R; Alaejos I; Orfão A; Rasillo A; Chillón M C; Tabernero M D; Mateos M V; López-Pérez R; González D; Balanzategui A; González M; San Miguel J F; Bortolucci A
Low frequency of the TEL/AML1 fusion gene in acute lymphoblastic leukaemia in Spain.
British journal of haematology 1999;107(3):667-9.
1999: Almeida J; Orfao A; Ocqueteau M; Mateo G; Corral M; Caballero M D; Blade J; Moro M J; Hernandez J; San Miguel J F
High-sensitive immunophenotyping and DNA ploidy studies for the investigation of minimal residual disease in multiple myeloma.
British journal of haematology 1999;107(1):121-31.
1999: Orfao A; Schmitz G; Brando B; Ruiz-Arguelles A; Basso G; Braylan R; Rothe G; Lacombe F; Lanza F; Papa S; Lucio P; San Miguel J F
Clinically useful information provided by the flow cytometric immunophenotyping of hematological malignancies: current status and future directions.
Clinical chemistry 1999;45(10):1708-17.
1999: González M; González D; López-Pérez R; García-Sanz R; Chillón M C; Balanzategui A; Mateos M V; Alaejos I; Langerak A W; Orfão A; Van Dongen J J; San Miguel J F
Heteroduplex analysis of VDJ amplified segments from rearranged IgH genes for clonality assessments in B-cell non-Hodgkin's lymphoma. A comparison between different strategies.
Haematologica 1999;84(9):779-84.
1999: García J L; Gutiérrez N C; Hernández J M; Sánchez M A; González M B; Arroyo J L; San Miguel J F
[Comparative genomic hybridization. Methodologic features]
Sangre 1999;44(4):291-6.
1999: Díaz-Agustín B; Escribano L; Bravo P; Herrero S; Nuñez R; Navalón R; Navarro L; Torrelo A; Cantalapiedra A; Del Castillo L; Villarrubia J; Navarro J L; San Miguel J F; Orfao A
The CD69 early activation molecule is overexpressed in human bone marrow mast cells from adults with indolent systemic mast cell disease.
British journal of haematology 1999;106(2):400-5.
1999: Amigo M L; del Cañizo M C; Caballero M D; Vazquez L; Corral M; Vidriales B; Brufau A; San Miguel J F
Factors that influence long-term hematopoietic function following autologous stem cell transplantation.
Bone marrow transplantation 1999;24(3):289-93.
1999: Amigo M L; del Cañizo M C; Rios A; Garcia M A; Caballero M D; Martin A; Bermejo N; Vilches P; San Miguel J F
Diagnosis of secondary myelodysplastic syndromes (MDS) following autologous transplantation should not be based only on morphological criteria used for diagnosis of de novo MDS.
Bone marrow transplantation 1999;23(10):997-1002.
1999: del Cañizo C; Lopez N; Caballero D; Fernandez E; Brufau A; Vazquez L; Mateos V; Gutierrez N; San Miguel J F
Haematopoietic damage persists 1 year after autologous peripheral blood stem cell transplantation.
Bone marrow transplantation 1999;23(9):901-5.
1999: Orfao A; Chillón M C; Bortoluci A M; López-Berges M C; García-Sanz R; Gonzalez M; Tabernero M D; García-Marcos M A; Rasillo A I; Hernández-Rivas J; San Miguel J F
The flow cytometric pattern of CD34, CD15 and CD13 expression in acute myeloblastic leukemia is highly characteristic of the presence of PML-RARalpha gene rearrangements.
Haematologica 1999;84(5):405-12.
1999: Martínez A; San Miguel J F; Vidriales M B; Ciudad J; Caballero M D; López-Berges M C; Moro M J; Calmuntia M J; Ortega F; Orfao A
An abnormal CD34+ myeloid/CD34+ lymphoid ratio at the end of chemotherapy predicts relapse in patients with acute myeloid leukemia.
Cytometry 1999;38(2):70-5.
1999: García-Sanz R; López-Pérez R; Langerak A W; González D; Chillón M C; Balanzategui A; Mateos M V; Alaejos I; González M; Van Dongen J J; San Miguel J F
Heteroduplex PCR analysis of rearranged immunoglobulin genes for clonality assessment in multiple myeloma.
Haematologica 1999;84(4):328-35.
1999: Ciudad J; San Miguel J F; López-Berges M C; García Marcos M A; González M; Vázquez L; del Cañizo M C; López A; Van Dongen J J; Orfao A
Detection of abnormalities in B-cell differentiation pattern is a useful tool to predict relapse in precursor-B-ALL.
British journal of haematology 1999;104(4):695-705.
1999: Lúcio P; Parreira A; van den Beemd M W; van Lochem E G; van Wering E R; Baars E; Porwit-MacDonald A; Bjorklund E; Gaipa G; Biondi A; Orfao A; Janossy G; van Dongen J J; San Miguel J F
Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(3):419-27.
1999: Cerveró C; Escribano L; San Miguel J F; Díaz-Agustín B; Bravo P; Villarrubia J; García-Sanz R; Velasco J L; Herrera P; Vargas M; González M; Navarro J L; Orfao A
Expression of Bcl-2 by human bone marrow mast cells and its overexpression in mast cell leukemia.
American journal of hematology 1999;60(3):191-5.
1999: Almeida J; Orfao A; Mateo G; Ocqueteau M; García-Sanz R; Moro M J; Hernandez J; Ortega F; Borrego D; Barez A; Mejido M; San Miguel J F
Immunophenotypic and DNA content characteristics of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance.
Pathologie-biologie 1999;47(2):119-27.
1999: Pérez-Simón J A; Valverde B; Martínez A; Tabernero D; Almeida J; Gutierrez N; San Miguel J F; Orfao A
Correlation of rhodamine 123 efflux by neoplastic plasma cells with clinical and biological characteristics of multiple myeloma.
Cytometry 1999;38(1):24-9.
1999: San Miguel J F; Bladé Creixenti J; García-Sanz R
Treatment of multiple myeloma.
Haematologica 1999;84(1):36-58.
1998: Ciudad J; Orfao A; Vidriales B; Macedo A; Martínez A; González M; López-Berges M C; Valverde B; San Miguel J F
Immunophenotypic analysis of CD19+ precursors in normal human adult bone marrow: implications for minimal residual disease detection.
Haematologica 1998;83(12):1069-75.
1998: Menéndez P; Redondo O; Rodriguez A; Lopez-Berges M C; Ercilla G; López A; Durán A; Almeida J; Pérez-Simón J A; San Miguel J F; Gratama J W; Orfao A
Comparison between a lyse-and-then-wash method and a lyse-non-wash technique for the enumeration of CD34+ hematopoietic progenitor cells.
Cytometry 1998;34(6):264-71.
1998: Ciudad J; San Miguel J F; López-Berges M C; Vidriales B; Valverde B; Ocqueteau M; Mateos G; Caballero M D; Hernández J; Moro M J; Mateos M V; Orfao A
Prognostic value of immunophenotypic detection of minimal residual disease in acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(12):3774-81.
1998: Escribano L; Orfao A; Díaz Agustín B; Cerveró C; Herrero S; Villarrubia J; Bravo P; Torrelo A; Montero T; Valdemoro M; Velasco J L; Navarro J L; San Miguel J F
Human bone marrow mast cells from indolent systemic mast cell disease constitutively express increased amounts of the CD63 protein on their surface.
Cytometry 1998;34(5):223-8.
1998: Hernández J M; Gutiérrez N C; Almeida J; García J L; Sánchez M A; Mateo G; Ríos A; San Miguel J F
IL-4 improves the detection of cytogenetic abnormalities in multiple myeloma and increases the proportion of clonally abnormal metaphases.
British journal of haematology 1998;103(1):163-7.
1998: del Cañizo M C; Brufau A; Almeida J; Galende J; García Marcos M A; Mota A; García R; Fernández Calvo J; Ramos F; Fisac P; Orfao A; San Miguel J F
In vitro growth in acute myeloblastic leukaemia: relationship with other clinico-biological characteristics of the disease.
British journal of haematology 1998;103(1):137-42.
1998: Amigo M L; del Cañizo M C; Hernández J M; Gonzalez M B; Gutiérrez N; Mateos M V; San Miguel J F
Clonal myelodysplastic cells present in apheresis product before transplantation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(9):1497-9.
1998: San Miguel J F; García-Sanz R
Recombinant human erythropoietin in the anaemia of multiple myeloma and non-Hodgkin's lymphoma.
Medical oncology (Northwood, London, England) 1998;15 Suppl 1():S29-34.
1998: Escribano L; Ocqueteau M; Almeida J; Orfao A; San Miguel J F
Expression of the c-kit (CD117) molecule in normal and malignant hematopoiesis.
Leukemia & lymphoma 1998;30(5-6):459-66.
1998: Bladé J; San Miguel J F; Escudero M L; Fontanillas M; Besalduch J; Gardella S; Arias J; García-Conde J; Carnero M; Marti J M; Rozman C; Estapé J; Montserrat E
Maintenance treatment with interferon alpha-2b in multiple myeloma: a prospective randomized study from PETHEMA (Program for the Study and Treatment of Hematological Malignancies, Spanish Society of Hematology).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(7):1144-8.
1998: Caballero M D; Vazquez L; Barragan J M; Cruz J J; Gomez A; Nieto M J; Corral M; Fonseca E; San Miguel J F
Randomized study of filgrastim versus molgramostim after peripheral stem cell transplant in breast cancer.
Haematologica 1998;83(6):514-8.
1998: Hernández M D; del Cañizo M C; González M; Caballero M D; López-Berges M C; Vázquez L; Orfao A; Corral M; Nieto M J; San Miguel J F
[Immune reconstitution after autologous progenitor hemopoietic cell transplantation. A study comparing autologous bone marrow and autologous peripheral blood transplantation]
Medicina clínica 1998;110(20):768-73.
1998: Ocqueteau M; Orfao A; Almeida J; Bladé J; González M; García-Sanz R; López-Berges C; Moro M J; Hernández J; Escribano L; Caballero D; Rozman M; San Miguel J F
Immunophenotypic characterization of plasma cells from monoclonal gammopathy of undetermined significance patients. Implications for the differential diagnosis between MGUS and multiple myeloma.
The American journal of pathology 1998;152(6):1655-65.
1998: Laso F J; Iglesias M C; López A; Ciudad J; San Miguel J F; Orfao A
Increased interleukin-12 serum levels in chronic alcoholism.
Journal of hepatology 1998;28(5):771-7.
1998: Pérez-Simón J A; García-Sanz R; Tabernero M D; Almeida J; González M; Fernández-Calvo J; Moro M J; Hernández J M; San Miguel J F; Orfão A
Prognostic value of numerical chromosome aberrations in multiple myeloma: A FISH analysis of 15 different chromosomes.
Blood 1998;91(9):3366-71.
1998: Pérez-Simón J A; Caballero M D; Corral M; Nieto M J; Orfao A; Vazquez L; Amigo M L; Berges C; González M; Del Cañizo C; San Miguel J F
Minimal number of circulating CD34+ cells to ensure successful leukapheresis and engraftment in autologous peripheral blood progenitor cell transplantation.
Transfusion 1998;38(4):385-91.
1998: Ribera J M; Ortega J J; Oriol A; Fontanillas M; Hernández-Rivas J M; Brunet S; García-Conde J; Maldonado J; Zuazu J; Gardella S; Besalduch J; León P; Macià J; Domingo-Albós A; Feliu E; San Miguel J F
Late intensification chemotherapy has not improved the results of intensive chemotherapy in adult acute lymphoblastic leukemia. Results of a prospective multicenter randomized trial (PETHEMA ALL-89). Spanish Society of Hematology.
Haematologica 1998;83(3):222-30.
1998: García-Sanz R; Vargas Montero M; Gonzalez Díaz M; del Carmen M; Santos C; Balanzategui Echevarria A; Flores Corral T; Hernández Martín J M; Caballero Barrigón M D; San Miguel J F
Detection of single and associated lesions of the Bcl-1, Bcl-2, Bcl-6, c-myc, p53 and p16 genes in B-cell non-Hodgkin's lymphomas: value of molecular analysis for a better assignment of the histologic subtype.
Haematologica 1998;83(3):209-16.
1998: Del Cañizo M C; Brufau A; Mota A; Lopez N; Fernandez M E; Vallejo C; Hernandez J M; Garcia J L; San Miguel J F
The value of cell cultures for the diagnosis of mixed myelodysplastic/myeloproliferative disorders.
Haematologica 1998;83(1):3-7.
1998: Escribano L; Orfao A; Villarrubia J; Díaz-Agustín B; Cerveró C; Rios A; Velasco J L; Ciudad J; Navarro J L; San Miguel J F
Immunophenotypic characterization of human bone marrow mast cells. A flow cytometric study of normal and pathological bone marrow samples.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1998;16(3):151-9.
1997: García-Sanz R; González M; Vargas M; Chillón M C; Balanzategui A; Barbón M; Flores M T; San Miguel J F
Deletions and rearrangements of cyclin-dependent kinase 4 inhibitor gene p16 are associated with poor prognosis in B cell non-Hodgkin's lymphomas.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(11):1915-20.
1997: Vallejo C; Caballero M D; García-Sanz R; Hernández J M; Vázquez L; Cañizo M C; Galende J; Colino C I; Gil-Hurlé A; San Miguel J F
Sequential intravenous-oral ciprofloxacin plus amoxycillin/clavulanic acid shortens hospital stay in infected non severe neutropenic patients.
Hematology and cell therapy 1997;39(5):223-7.
1997: Laso F J; Lapeña P; Madruga J I; San Miguel J F; Orfao A; Iglesias M C; Alvarez-Mon M
Alterations in tumor necrosis factor-alpha, interferon-gamma, and interleukin-6 production by natural killer cell-enriched peripheral blood mononuclear cells in chronic alcoholism: relationship with liver disease and ethanol intake.
Alcoholism, clinical and experimental research 1997;21(7):1226-31.
1997: Amigo M L; Caballero M D; Vazquez L; Flores T; López A; San Miguel J F
Immune thrombocytopenic purpura secondary to endometriosis.
Haematologica 1997;82(5):602-3.
1997: García-Isidoro M; Tabernero M D; Najera M L; García J L; Hernandez J M; Duran A; San Miguel J F; Orfao A
Clinical and biological characteristics of myelodysplastic syndromes with nulisomy Y by fish.
Haematologica 1997;82(5):537-41.
1997: Vallejo C; García-Marcos M A; Del Cañizo M C; Orfao A; Almeida J; Escribano L; San Miguel J F; Ríos A
[Syndrome of abnormal chromatin clumping in leucocytes with a high fraction of bone marrow cells in S-phase and in vitro autonomous growth]
Medicina clínica 1997;109(9):340-2.
1997: Martínez A; San Miguel J F; Valverde B; Bárez A; Moro M J; García-Marcos M A; Pérez-Simón J A; Vidriales B; Orfao A
Functional expression of MDR-1 in acute myeloid leukemia: correlation with the clinical-biological, immunophenotypical, and prognostic disease characteristics.
Annals of hematology 1997;75(3):81-6.
1997: Caballero M D; Rubio V; Rifon J; Heras I; García-Sanz R; Vázquez L; Vidriales B; del Cañizo M C; Corral M; Gonzalez M; León A; Jean-Paul E; Rocha E; Moraleda J M; San Miguel J F
BEAM chemotherapy followed by autologous stem cell support in lymphoma patients: analysis of efficacy, toxicity and prognostic factors.
Bone marrow transplantation 1997;20(6):451-8.
1997: San Miguel J F; Martínez A; Macedo A; Vidriales M B; López-Berges C; González M; Caballero D; García-Marcos M A; Ramos F; Fernández-Calvo J; Calmuntia M J; Diaz-Mediavilla J; Orfao A
Immunophenotyping investigation of minimal residual disease is a useful approach for predicting relapse in acute myeloid leukemia patients.
Blood 1997;90(6):2465-70.
1997: Del Cañizo M C; Galende J; Mota A; Orfao A; Martinez A; Almeida J; San Miguel J F
In leukemic hematopoiesis CD34 antigen does not have the same significance as it does normal hematopoiesis.
Leukemia research 1997;21(7):651-6.
1997: Garcia-Isidoro M; Tabernero M D; Najera M L; Lopez-Berges M C; Martinez A; Durán A; Garcia J L; Hernandez J M; Garcia Marcos M A; San Miguel J F; Orfao A
Association between trisomy 8 and the immunophenotype of blast cells from acute leukemias secondary to a myelodysplastic syndrome or chronic myeloproliferative disorders.
Annals of hematology 1997;74(5):209-14.
1997: Laso F J; Madruga J I; Girón J A; López A; Ciudad J; San Miguel J F; Alvarez-Mon M; Orfao A
Decreased natural killer cytotoxic activity in chronic alcoholism is associated with alcohol liver disease but not active ethanol consumption.
Hepatology (Baltimore, Md.) 1997;25(5):1096-100.
1997: Caballero D; Rubio V; Rifon J; Heras I; García-Sanz R; Vidriales B; Pérez-Simón J A; del Cañizo C; González M; León A; Jean-Paul E; Rocha E; Vicente V; San Miguel J F
[Autologous transplant with BEAM protocol in lymphoma]
Sangre 1997;42 Suppl 1():46-9.
1997: Escribano L; Orfao A; Villarrubia J; Martín F; Madruga J I; Cuevas M; Velasco J L; Rios A; San Miguel J F
Sequential immunophenotypic analysis of mast cells in a case of systemic mast cell disease evolving to a mast cell leukemia.
Cytometry 1997;30(2):98-102.
1997: López L; Portero J A; Borrego D; Barez A; San Miguel J F
[High cardiac output in myeloma patients. Its prevalence and clinical characteristics. The Castile-León Cooperative Group for the Study of Monoclonal Gammapathies]
Medicina clínica 1997;108(6):214-6.
1997: Caballero M D; Amigo M L; Hernández J M; Vazquez L; del Cañizo C; Gonzalez M; García R; San Miguel J F
Alternating mini-BEAM/ESHAP as salvage therapy for refractory non-Hodgkin's lymphomas.
Annals of hematology 1997;74(2):79-82.
1997: Sanfructuoso C; Caballero M D; Vázquez L; Galende J; Almeida J; San Miguel J F
Rhabdomyolysis associated with septicemia after autologous bone marrow transplantation.
Bone marrow transplantation 1997;19(1):95.
1996: Laso F J; Madruga J I; San Miguel J F; Ciudad J; López A; Alvarez Mon M; Orfao A
Long lasting immunological effects of ethanol after withdrawal.
Cytometry 1996;26(4):275-80.
1996: Dolbeare F; Lopez N; Lopez A; Amigo M L; Ciudad J; Del Cañizo M C; San Miguel J F; Orfao A
Multiparametric cell-cycle analysis of peripheral blood-activated lymphocyte subsets using staining based on the TdT method for incorporated BrdUrd.
Cytometry 1996;25(4):317-23.
1996: Ocqueteau M; Orfao A; García-Sanz R; Almeida J; Gonzalez M; San Miguel J F
Expression of the CD117 antigen (c-Kit) on normal and myelomatous plasma cells.
British journal of haematology 1996;95(3):489-93.
1996: Orfao A; Escribano L; Villarrubia J; Velasco J L; Cerveró C; Ciudad J; Navarro J L; San Miguel J F
Flow cytometric analysis of mast cells from normal and pathological human bone marrow samples: identification and enumeration.
The American journal of pathology 1996;149(5):1493-9.
1996: López Holgado N; Consuelo del Cañizo M; Tabernero M D; Hernández M D; Vallejo C; San Miguel J F
[Long-term culture: evidence of the capacity of stroma to sustain hematopoiesis of a second inoculum]
Sangre 1996;41(5):345-9.
1996: San Miguel J F; García-Sanz R; González M; Orfão A
DNA cell content studies in multiple myeloma.
Leukemia & lymphoma 1996;23(1-2):33-41.
1996: Ocqueteau M; San Miguel J F; González M; Almeida J; Orfao A
Do myelomatous plasma cells really express surface immunoglobulins?
Haematologica 1996;81(5):460-3.
1996: González M; García-Sanz R; Vargas M; Balanzategui A; Chillón M C; Mateos M V; San Miguel J F
[Molecular biology in malignant blood diseases. Clinical applications. Study of immunoglobulin and T-cell receptor genes and molecular analysis of the translocations]
Sangre 1996;41(4):321-34.
1996: González M; García Sanz R; Chillon M C; Balanzategui A; Vargas M; García M F; San Miguel J F
[Molecular biology in malignant blood diseases. Methodological aspects: Southern blotting techniques and the polymerase chain reaction]
Sangre 1996;41(4):311-9.
1996: San Miguel J F; Hernández M D; Gonzalez M; López-Berges M C; Caballero M D; Vazquez L; Orfao A; Nieto M J; Corral M; del Cañizo M C
A randomized study comparing the effect of GM-CSF and G-CSF on immune reconstitution after autologous bone marrow transplantation.
British journal of haematology 1996;94(1):140-7.
1996: Tabernero D; San Miguel J F; Garcia-Sanz M; Nájera L; García-Isidoro M; Peréz-Simon J A; Gonzalez M; Wiegant J; Raap A K; Orfão A
Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes.
The American journal of pathology 1996;149(1):153-61.
1996: Bladé J; San Miguel J F; Fontanillas M; Alcalá A; Maldonado J; García-Conde J; Conde E; Conzález-Brito G; Moro M J; Escudero M L; Trujillo J; Pascual A; Rozman C; Estapé J; Montserrat E
Survival of multiple myeloma patients who are potential candidates for early high-dose therapy intensification/ autotransplantation and who were conventionally treated.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(7):2167-73.
1996: del Cañizo M C; Mota A; Orfao A; Galende J; Caballero M D; Garcia Marcos M A; San Miguel J F
Value of colony forming unit-granulocyte macrophage assay in predicting relapse in acute myeloid leukaemia.
Journal of clinical pathology 1996;49(6):450-2.
1996: Almeida J; Consuelo Del Cañizo M; Galende J; San Miguel J F
Responsiveness of AML cells to recombinant hematopoietic growth factors: relationship with morphological and immunological characteristics of blast cells.
Leukemia research 1996;20(6):533-4.
1996: San Miguel J F; Sanz G F; Vallespí T; del Cañizo M C; Sanz M A
Myelodysplastic syndromes.
Critical reviews in oncology/hematology 1996;23(1):57-93.
1996: García-Sanz R; González M; Orfão A; Moro M J; Hernández J M; Borrego D; Carnero M; Casanova F; Bárez A; Jiménez R; Portero J A; San Miguel J F
Analysis of natural killer-associated antigens in peripheral blood and bone marrow of multiple myeloma patients and prognostic implications.
British journal of haematology 1996;93(1):81-8.
1996: Sanfructuoso C; Caballero M D; Garcia-Sanz R; Vidriales B; Vazquez L; San Miguel J F
Relapse of multiple myeloma in extramedullary sites after autologous bone marrow transplantation.
European journal of haematology 1996;56(3):181-3.
1996: Macedo A; San Miguel J F; Vidriales M B; López-Berges M C; García-Marcos M A; Gonzalez M; Landolfi C; Orfão A
Phenotypic changes in acute myeloid leukaemia: implications in the detection of minimal residual disease.
Journal of clinical pathology 1996;49(1):15-8.
1995: Amigo M L; Revilla R; Sánchez C; del Cañizo C; Caballero D; San Miguel J F
[Spinal cord compression as the presenting form of non-Hodgkin's lymphoma]
Sangre 1995;40(6):505-7.
1995: Escribano L; Orfao A; Villarrubia J; Cerveró C; Velasco J L; Martín F; San Miguel J F; Navarro J L
Expression of lymphoid-associated antigens in mast cells: report of a case of systemic mast cell disease.
British journal of haematology 1995;91(4):941-3.
1995: Macedo A; Orfao A; Ciudad J; Gonzalez M; Vidriales B; Lopez-Berges M C; Martínez A; Landolfi C; Cañizo C; San Miguel J F
Phenotypic analysis of CD34 subpopulations in normal human bone marrow and its application for the detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(11):1896-901.
1995: Almeida J; García-Marcos M A; Vallejo C; Flores M T; Caballero M D; San Miguel J F; Ríos A
[Results of a series of 104 consecutive bilateral bone marrow biopsy specimens in lymphoproliferative disorders]
Sangre 1995;40(5):365-8.
1995: Tabernero M D; San Miguel J F; Garcia J L; Garcia-Isidoro M; Wiegant J; Ciudad J; Gonzalez M; Rios A; Raap A; Orfao A
Clinical, biological, and immunophenotypical characteristics of B-cell chronic lymphocytic leukemia with trisomy 12 by fluorescence in situ hybridization.
Cytometry 1995;22(3):217-22.
1995: Macedo A; Orfão A; Gonzalez M; Vidriales M B; López-Berges M C; Martínez A; San Miguel J F
Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: implications for minimal residual disease studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(6):993-8.
1995: Almeida J; del Cañizo C; Orfao A; Hernandez J; Hernandez D; Galende J; Caballero D; Garcia-Sanz R; San Miguel J F
In vitro autonomous proliferation in ANLL: clinical and biological significance.
Leukemia research 1995;19(6):411-6.
1995: Vidriales M B; Orfao A; López-Berges M C; González M; López-Macedo A; García M A; Galende J; San Miguel J F
Light scatter characteristics of blast cells in acute myeloid leukaemia: association with morphology and immunophenotype.
Journal of clinical pathology 1995;48(5):456-62.
1995: Iglesias-Osma C; Gonzalez-Villaron L; San Miguel J F; Caballero M D; Vazquez L; de Castro S
Iron metabolism and fungal infections in patients with haematological malignancies.
Journal of clinical pathology 1995;48(3):223-5.
1995: Vidriales M B; Orfao A; López-Berges M C; González M; López-Macedo A; Ciudad J; López A; Cañizo M C; Garcia M A; San Miguel J F
DNA aneuploidy in acute myeloblastic leukemia is associated with a high expression of lymphoid markers.
Cytometry 1995;22(1):22-5.
1995: Macedo A; Orfao A; Martínez A; Vidriales M B; Valverde B; López-Berges M C; San Miguel J F
Immunophenotype of c-kit cells in normal human bone marrow: implications for the detection of minimal residual disease in AML.
British journal of haematology 1995;89(2):338-41.
1995: San Miguel J F; García-Sanz R; González M; Moro M J; Hernández J M; Ortega F; Borrego D; Carnero M; Casanova F; Jiménez R
A new staging system for multiple myeloma based on the number of S-phase plasma cells.
Blood 1995;85(2):448-55.
1995: Sánchez I; San Miguel J F; Corral J; Martín C; Pérez R; González M; Cañizo M C; Orfao A; González-Sarmiento R
Gene rearrangement in acute non-lymphoblastic leukaemia: correlation with morphological and immunophenotypic characteristics of blast cells.
British journal of haematology 1995;89(1):104-9.
1995: Orfao A; Ciudad J; Gonzalez M; Lopez A; del Mar Abad M; Paz Bouza J I; Cruz J J; Gomez Alonso A; San Miguel J F
Flow cytometry in the diagnosis of cancer.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1995;221():145-52.
1994: Orfäo A; García-Sanz R; López-Berges M C; Belén Vidriales M; González M; Caballero M D; San Miguel J F
A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique.
Cytometry 1994;17(4):332-9.
1994: Galende J; Vazquez M L; Almeida J; Peña Penabad M C; Fernandez Lopez E; Caballero M D; San Miguel J F
Histiocytic cytophagic panniculitis: a rare late complication of allogeneic bone marrow transplantation.
Bone marrow transplantation 1994;14(4):637-9.
1994: Almeida J; del Cañizo M C; Galende J; Vidriales B; Nieto M J; Hernández M D; Rodríguez M J; San Miguel J F
[Clonogenic cells of acute leukemia secondary to myeloproliferative and myelodysplastic syndromes]
Sangre 1994;39(5):331-5.
1994: Macedo A; Orfao A; Ciudad J; San Miguel J F
[Phenotypic characterization of normal myeloid differentiation]
Sangre 1994;39(4):277-82.
1994: del Cañizo M C; Almeida J; San Miguel J F; Orfao A; Gonzalez M; Lopez Borrasca A
The phenotype of L-CFU and its correlation with the immunological characteristics of the blast cell population in AML.
Annals of hematology 1994;68(5):233-6.
1994: García-Sanz R; Alberca I; Vázquez L; Hernández J M; Castellanos A; San Miguel J F
[Control of oral anticoagulant treatment using an automated method]
Sangre 1994;39(2):95-8.
1994: Orfao A; Ciudad J; Lopez-Berges M C; Lopez A; Vidriales B; Caballero M D; Valverde B; Gonzalez M; San Miguel J F
Acute lymphoblastic leukemia (ALL): detection of minimal residual disease (MRD) at flow cytometry.
Leukemia & lymphoma 1994;13 Suppl 1():87-90.
1993: García R; Hernández J M; Caballero M D; González M; Galende J; del Cañizo M C; Vázquez L; San Miguel J F
Serum lactate dehydrogenase level as a prognostic factor in Hodgkin's disease.
British journal of cancer 1993;68(6):1227-31.
1993: Vidriales M B; Orfao A; López-Berges M C; González M; Hernandez J M; Ciudad J; López A; Moro M J; Martínez M; San Miguel J F
Lymphoid subsets in acute myeloid leukemias: increased number of cells with NK phenotype and normal T-cell distribution.
Annals of hematology 1993;67(5):217-22.
1993: Hernández J M; Sánchez I; González M; Orfao A; González-Sarmiento R; San Miguel J F
Acute lymphoid leukemias following either a previous chronic myelogenous leukemia or myelodysplastic syndrome: phenotypic and genomic differences.
American journal of hematology 1993;43(4):256-8.
1993: Bladé J; San Miguel J F; Alcalá A; Maldonado J; Sanz M A; García-Conde J; Moro M J; Alonso C; Besalduch J; Zubizarreta A
Alternating combination VCMP/VBAP chemotherapy versus melphalan/prednisone in the treatment of multiple myeloma: a randomized multicentric study of 487 patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(6):1165-71.
1993: San Miguel J F; Hernandez J M; Gonzalez R; Gonzalez M; Sanchez I; Orfao A; del Cañizo M C; Lopez-Borrasca A
Multiparameter analysis of blast cells in patients with acute leukemia following a primary myelodysplastic syndrome.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():393-400.
1993: Orfao A; Vidriales B; Gonzalez M; Lopez-Berges M C; del Cañizo M C; San Miguel J F
Diagnostic and prognostic importance of immunophenotyping in adults with acute myeloid leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():369-79.
1992: Ruiz-Argüelles G J; Lobato-Mendizábal E; San-Miguel J F; González M; Caballero M D; Ruiz-Argüelles A; Orfao A; Gómez-Almaguer D; Vidriales B; Ruiz-Reyes G
Long-term treatment results for acute megakaryoblastic leukaemia patients: a multicentre study.
British journal of haematology 1992;82(4):671-5.
1992: Caballero M D; González M; Cañizo M C; Orfao A; Nieto M J; San Miguel J F
Concomitant chronic lymphocytic leukemia (CLL) and acute myeloid leukemia. Complete remission of CLL achieved with high-dose cytosine arabinoside.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6(8):856-8.
1992: Hernández J M; San Miguel J F; González M; Orfao A; Cañizo M C; Bascones C; Hernández J; López Borrasca A
Development of acute leukaemia after idiopathic myelofibrosis.
Journal of clinical pathology 1992;45(5):427-30.
1992: San Miguel J F; González M; Gascón A; Moro M J; Hernández J M; Ortega F; Jiménez R; Guerras L; Romero M; Casanova F
Lymphoid subsets and prognostic factors in multiple myeloma. Cooperative Group for the Study of Monoclonal Gammopathies.
British journal of haematology 1992;80(3):305-9.
1992: Gonzalez M; San Miguel J F; Gascon A; Moro M J; Hernandez J M; Ortega F; Jimenez R; Guerras L; Romero M; Casanova F
Increased expression of natural-killer-associated and activation antigens in multiple myeloma.
American journal of hematology 1992;39(2):84-9.
1992: Orfao A; Ciudad J; González M; San Miguel J F; García A R; López-Berges M C; Ramos F; Del Cañizo M C; Ríos A; Sanz M
Prognostic value of S-phase white blood cell count in B-cell chronic lymphocytic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6(1):47-51.
1991: Hernández J M; González-Sarmiento R; Martin C; González M; Sánchez I; Corral J; Orfao A; Cañizo M C; San Miguel J F; López-Borrasca A
Immunophenotypic, genomic and clinical characteristics of blast crisis of chronic myelogenous leukaemia.
British journal of haematology 1991;79(3):408-14.
1991: Hernández J M; San Miguel J F; González M; Moraleda J M; Moro M J; Hernández J; Cuesta B; López Borrasca A
[Clinico-hematological characteristics of acute transformation of chronic myeloproliferative syndromes]
Medicina clínica 1991;97(10):369-72.
1991: Gómez E; San Miguel J F; González M; Orfao A; López-Berges C; Ríos A; López Borrasca A
Heterogeneity of T cell lymphoblastic leukaemias.
Journal of clinical pathology 1991;44(8):628-31.
1991: San Miguel J F; Hernández J M; González-Sarmiento R; González M; Sánchez I; Orfao A; Cañizo M C; López Borrasca A
Acute leukemia after a primary myelodysplastic syndrome: immunophenotypic, genotypic, and clinical characteristics.
Blood 1991;78(3):768-74.
1991: Gómez E; San Miguel J F; González M; Orfao A; Cañizo M C; Ciudad J; López Borrasca A
[Phenotypic changes in refractory and relapse acute lymphoblastic leukemias]
Sangre 1991;36(3):201-4.
1991: San Miguel J F; González M; Gascón A; Moro M J; Hernández J M; Ortega F; Jimenez R; Guerras L; Romero M; Casanova F
Immunophenotypic heterogeneity of multiple myeloma: influence on the biology and clinical course of the disease. Castellano-Leones (Spain) Cooperative Group for the Study of Monoclonal Gammopathies.
British journal of haematology 1991;77(2):185-90.
1991: San Miguel J F; Moro M; Bladé J; Guerras L; Hernandez J; Jiminez-Galindo R; Ortega F; Gonzalez M
Interferon and dexamethasone in multiple myeloma patients refractory to chemotherapy.
European journal of cancer (Oxford, England : 1990) 1991;27 Suppl 4():S48-9.
1990: San Miguel J F; Moro M; Bladé J; Guerras L; Hernandez J; Jimenez-Galindo R; Ortega F; Gonzalez M
Combination of interferon and dexamethasone in refractory multiple myeloma.
Hematological oncology 1990;8(4):185-9.
1990: Ríos A; Cañizo M C; Sanz M A; Vallespí T; Sanz G; Torrabadella M; Gomis F; Ruiz C; San Miguel J F
Bone marrow biopsy in myelodysplastic syndromes: morphological characteristics and contribution to the study of prognostic factors.
British journal of haematology 1990;75(1):26-33.
1990: del Cañizo M C; Almeida J; San Miguel J F
[The clonogenic cell in acute myeloblastic leukemia]
Sangre 1990;35(2):125-7.
1990: Orfao A; Gonzalez M; San Miguel J F; Tomas J F; Canizo M C; Lopez-Berges M C; Moraleda J M; Lopez Borrasca A
Surface phenotype and immunoglobulin levels in B-cell chronic lymphocytic leukaemia.
Haematologia 1990;23(1):49-56.
1989: Almeida J; Cañizo C; Sánchez I J; Nieto M J; San Miguel J F; González M; Orfao A
[Study of leukemic colony-forming units (CFU-L) in non-lymphoblastic malignant hemopathies]
Sangre 1989;34(6):467-70.
1989: Sanz G F; Sanz M A; Vallespí T; Cañizo M C; Torrabadella M; García S; Irriguible D; San Miguel J F
Two regression models and a scoring system for predicting survival and planning treatment in myelodysplastic syndromes: a multivariate analysis of prognostic factors in 370 patients.
Blood 1989;74(1):395-408.
1989: del Cañizo M C; Sanz G; San Miguel J F; Vallespi T; Irriguible D; Torrabadella M; Sanz M A
Chronic myelomonocytic leukemia--clinicobiological characteristics: a multivariate analysis in a series of 70 cases.
European journal of haematology 1989;42(5):466-73.
1989: San Miguel J F; Ojeda E; Gonzalez M; Orfao A; Cañizo M C; Sanchez J; Lopez-Borrasca A
Prognostic value of immunological markers in acute myeloblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1989;3(2):108-11.
1989: Sanz G F; Sanz M A; Vallespí T; Cañizo M C; García S; Torrabadella M; San Miguel J F; Irriguible D
[Prediction of survival in myelodysplastic syndrome. Analysis of 2 scoring systems with prognostic value]
Sangre 1989;34(1):41-6.
1988: San Miguel J F; Tomás J F; Martín M J; Ríos A; Moraleda J M; Cañizo M C; González M; Nieto M J; Sánchez J; López Borrasca A
[Non-Hodgkin's lymphomas. II. Prognostic factors]
Sangre 1988;33(5):367-71.
1988: Tomás J F; San Miguel J F; Martín M J; Martínez R; Moraleda J M; González M; Cañizo M C; Ojeda E; Ramos F; Flores T
[Non-Hodgkin's lymphomas. I. Clinico-biological features in a series of 98 patients]
Sangre 1988;33(5):361-6.
1988: Orfao A; González M; San Miguel J F; Corral M; Nieto M J; Cañizo M C; Hernández J; Fernández Calvo J; López Borrasca A
[Chronic B-cell lymphatic leukemia: autoimmune hemolytic anemias versus anemias caused by marrow failure]
Sangre 1988;33(4):296-300.
1988: Ojeda E; San Miguel J F; González M; Cañizo C; Orfao A; Ríos A; López-Borrasca A
[Comparative study of the FAB classification and an immunologic classification model for the acute myeloid leukemias]
Sangre 1988;33(4):291-5.
1988: San Miguel J F; Gonzalez M; Cañizo M C; Ojeda E; Orfao A; Caballero M D; Moro M J; Fisac P; Lopez Borrasca A
Leukemias with megakaryoblastic involvement: clinical, hematologic, and immunologic characteristics.
Blood 1988;72(2):402-7.
1988: Del Cañizo M C; Ojeda E; San Miguel J F; Brufau A; González M; Orfao A; Ríos A; López Borrasca A
[Effect of a leukocyte medium conditioned with PHA on the proliferation and differentiation of leukemic cells]
Sangre 1988;33(1):15-9.
1988: Orfao A; Gonzalez M; San Miguel J F; Cañizo M C; Galindo P; Caballero M D; Jimenez R; Lopez Borrasca A
Clinical and immunological findings in large B-cell chronic lymphocytic leukemia.
Clinical immunology and immunopathology 1988;46(2):177-85.
1987: del Canizo M C; San Miguel J F; Gonzalez M; Anta J P; Orfao A; Lopez-Borrasca A
Discrepancies between morphologic, cytochemical, and immunologic characteristics in acute myeloblastic leukemia.
American journal of clinical pathology 1987;88(1):38-42.
1987: Gonzalez M; San Miguel J F; Anta J P; Ojeda E; Lopez-Borrasca A
Cell lineage switches in blast crisis of a Ph1 positive chronic granulocytic leukemia.
Haematologica 1987;72(3):249-51.
1987: Orfao A; Gonzalez M; San Miguel J F; Moro M J; Fernandez-Calvo J; Carnero M; Galindo P; Lopez Borrasca A
Surface phenotype and clinical stages in B-cell chronic lymphocytic leukaemia.
Haematologica 1987;72(1):39-43.
1987: del Cañizo M C; San Miguel J F; Gascón A; Rios A; Moraleda J M; González M; Anta J P; Sánchez J; López Borrasca A
[Myelodysplastic syndromes: characterization of a series of 56 patients classified according to FAB criteria]
Sangre 1987;32(4):436-44.
1986: San Miguel J F; Gonzalez M; Cañizo M C; Anta J P; Zola H; Lopez Borrasca A
Surface marker analysis in acute myeloid leukaemia and correlation with FAB classification.
British journal of haematology 1986;64(3):547-60.
1986: Moraleda J M; Gonzalez R; Alegre A; Anta J P; San Miguel J F
Bone marrow necrosis and treatment with interferon.
Journal of clinical pathology 1986;39(9):1045.
1986: San Miguel J F; González M; Cañizo M C; Anta J P; Portero J A; López-Borrasca A
TdT activity in acute myeloid leukemias defined by monoclonal antibodies.
American journal of hematology 1986;23(1):9-17.
1986: San Miguel J F; González M; Cañizo M C; Anta J P; Hernández J; Ortega F; Borrasca L
The nature of blast cells in myelodysplastic syndromes evolving to acute leukaemia.
Blut 1986;52(6):357-63.
1986: Orfao A; González M; San Miguel J F; Galindo P; Moro M J; Jiménez Galindo R; Bascones C; López Borrasca A
[Clinico-pathological features and clinical stages in chronic lymphatic leukemia. Multivariate analysis]
Sangre 1986;31(5):550-8.
1985: San Miguel J F; González M; Cañizo M C; Anta J P; Moraleda J M; Ríos A; Caballero M D; Ortega F; López Borrasca A
[The megakaryoblastic component of mixed blast crises]
Sangre 1985;30(3):330-6.
1984: San Miguel J F; González M; Caballero M D; Ríos A; Santoro T; Zola H; López Borrasca A
[Immunologic characterization of hairy-cell leukemia or tricholeukemia]
Sangre 1984;29(3):280-6.
1983: del Cañizo M C; San Miguel J F; Caballero M D; González M; Ríos A
[Cytochemistry of tricholeukemia]
Sangre 1983;28(6):794-5.
1983: San Miguel J F; Portero J A; Gonzalez M; Plaza J P; Caballero M D; De Cecilia A; Fernández J J; López Borrasca A
[The importance of terminal deoxyribonucleotidyl transferase in myeloblastic leukemias. Apropos of 2 cases]
Sangre 1983;28(6):746-52.

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