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Gerard Sanacora

Research Profile

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TOP 3
Michael H Bloch; John H Krystal; Angeli Landeros-Weisenberger; James F Leckman; Kaitlyn E Panza; Zubin Bhagwagar; Eileen Billingslea; Gerard Sanacora; Suzanne Wasylink; Christopher Pittenger
Effects of ketamine in treatment-refractory obsessive-compulsive disorder.
Gonzalo Laje; Níall Lally; Daniel Mathews; Francis J McMahon; Gerard Sanacora; Arthur Simen; Nirmala Akula; Nancy Brutsche; Anat Chemerinski; Benjamin Kelmendi; Carlos A Zarate
Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.
Chadi Abdallah; Madonna K Fasula; Ben Kelmendi; Gerard Sanacora; Robert B Ostroff
Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting.

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2012: Michael H Bloch; John H Krystal; Angeli Landeros-Weisenberger; James F Leckman; Kaitlyn E Panza; Zubin Bhagwagar; Eileen Billingslea; Gerard Sanacora; Suzanne Wasylink; Christopher Pittenger
Effects of ketamine in treatment-refractory obsessive-compulsive disorder.
Biological psychiatry 2012;72(11):964-70.
2012: Gonzalo Laje; Níall Lally; Daniel Mathews; Francis J McMahon; Gerard Sanacora; Arthur Simen; Nirmala Akula; Nancy Brutsche; Anat Chemerinski; Benjamin Kelmendi; Carlos A Zarate
Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.
Biological psychiatry 2012;72(11):e27-8.
2012: Chadi Abdallah; Madonna K Fasula; Ben Kelmendi; Gerard Sanacora; Robert B Ostroff
Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting.
The journal of ECT 2012;28(3):157-61.
2012: Peter T Morgan; Edward F Pace-Schott; Madonna Fasula; Erica Forselius; Graeme F Mason; Gerald W Valentine; Gerard Sanacora
Cortical GABA levels in primary insomnia.
Sleep 2012;35(6):807-14.
2012: Golam M I Chowdhury; Douglas L Rothman; Kevin L Behar; William Cho; Monique A Thomas; Gerard Sanacora
¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism.
Biological psychiatry 2012;71(11):1022-5.
2012: Dennis J McCarthy; Sanjeev Pathak; Robert Alexander; Stephen Kanes; Chi-Ming Lee; Mark A Smith; Gerard Sanacora
Glutamate-based depression GBD.
Medical hypotheses 2012;78(5):675-81.
2012: Shannon L Gourley; Gerard Sanacora; Jonathan W Espitia; Jane R Taylor
Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice.
Psychopharmacology 2012;219(3):805-14.
2012: Gerard Sanacora; Giulia Treccani; Maurizio Popoli
Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders.
Neuropharmacology 2012;62(1):63-77.
2011: Aybala Saricicek; Hilary P Blumberg; Boris Lorberg; Kathleen Maloney; Anjana Muralidharan; Brian Pittman; Barbara Ruf; Gerard Sanacora; Zubin Bhagwagar
Levetiracetam in the management of bipolar depression: a randomized, double-blind, placebo-controlled trial.
The Journal of clinical psychiatry 2011;72(6):744-50.
2011: Gerald W Valentine; Graeme F Mason; Rosane Gomez; Madonna K Fasula; June Watzl; Brian Pittman; John H Krystal; Gerard Sanacora
The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS.
Psychiatry research 2011;191(2):122-7.
2010: Mathilde M Husky; Claire Gindre; Carolyn M Mazure; Catherine Brebant; Susan Nolen-Hoeksema; Gerard Sanacora; Joel Swendsen
Computerized ambulatory monitoring in mood disorders: feasibility, compliance, and reactivity.
Psychiatry research 2010;178(2):440-2.
2010: Mounira Banasr; Dr. Golam M. I. Chowdhury; R Terwilliger; Samuel S Newton; Ronald S Duman; Kevin L Behar; Gerard Sanacora
Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole.
Molecular psychiatry 2010;15(5):501-11.
2010: Gerard Sanacora
Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?
Biological psychiatry 2010;67(5):397-8.
2010: Dorota Maciag; Jonathan Hughes; Gillian O'Dwyer; Yilianys Pride; Craig A Stockmeier; Gerard Sanacora; Grazyna Rajkowska
Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies.
Biological psychiatry 2010;67(5):465-70.
2009: Gerard Sanacora
Do glutamatergic agents represent a new class of antidepressant drugs? Part 2.
The Journal of clinical psychiatry 2009;70(11):1604-5.
2009: Gerard Sanacora
Do glutamatergic agents represent a new class of antidepressant drugs? Part 1.
The Journal of clinical psychiatry 2009;70(10):1473-5.
2009: Gerald W Valentine; Gerard Sanacora
Targeting glial physiology and glutamate cycling in the treatment of depression.
Biochemical pharmacology 2009;78(5):431-9.
2009: John H Krystal; David F Tolin; Gerard Sanacora; Stacy A Castner; Graham V Williams; Deane E Aikins; Ralph E Hoffman; D Cyril D'Souza
Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia.
Drug discovery today 2009;14(13-14):690-7.
2008: Dr. Golam M. I. Chowdhury; Mounira Banasr; Robin A de Graaf; Douglas L Rothman; Kevin L Behar; Gerard Sanacora
Chronic riluzole treatment increases glucose metabolism in rat prefrontal cortex and hippocampus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(12):1892-7.
2008: Srijan Sen; Ronald Duman; Gerard Sanacora
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications.
Biological psychiatry 2008;64(6):527-32.
2008: Srijan Sen; Gerard Sanacora
Major depression: emerging therapeutics.
The Mount Sinai journal of medicine, New York 2008;75(3):204-25.
2008: Gerard Sanacora; Carlos A Zarate; John H Krystal; Husseini K Manji
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders.
Nature reviews. Drug discovery 2008;7(5):426-37.
2008: Gerard Sanacora
New understanding of mechanisms of action of bipolar medications.
The Journal of clinical psychiatry 2008;69 Suppl 5():22-7.
2008: Christopher Pittenger; Vladimir Coric; Mounira Banasr; Michael Bloch; John H Krystal; Gerard Sanacora
Riluzole in the treatment of mood and anxiety disorders.
CNS drugs 2008;22(9):761-86.
2007: Gerard Sanacora; Aybala Saricicek
GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action.
CNS & neurological disorders drug targets 2007;6(2):127-40.
2007: Christopher Pittenger; Gerard Sanacora; John H Krystal
The NMDA receptor as a therapeutic target in major depressive disorder.
CNS & neurological disorders drug targets 2007;6(2):101-15.
2007: Gerard Sanacora; Steven F Kendell; Yael Levin; Arthur A Simen; Lisa R Fenton; Vladimir Coric; John H Krystal
Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms.
Biological psychiatry 2007;61(6):822-5.
2007: Yann S Mineur; Marina R Picciotto; Gerard Sanacora
Antidepressant-like effects of ceftriaxone in male C57BL/6J mice.
Biological psychiatry 2007;61(2):250-2.
2006: Lisa R Fenton; Madonna K Fasula; Robert B Ostroff; Gerard Sanacora
Can cognitive behavioral therapy reduce relapse rates of depression after ECT? a preliminary study.
The journal of ECT 2006;22(3):196-8.
2006: Ralitza Gueorguieva; Gerard Sanacora
Joint analysis of repeatedly observed continuous and ordinal measures of disease severity.
Statistics in medicine 2006;25(8):1307-22.
2006: Christopher Pittenger; Christine Naungayan; Steven F Kendell; Vladimir Coric; Robert T Malison; John H Krystal; Gerard Sanacora
Visual hallucinations from the addition of riluzole to memantine and bupropion.
Journal of clinical psychopharmacology 2006;26(2):218-20.
2006: Thomas D Geracioti; Linda L Carpenter; Michael J Owens; Dewleen G Baker; Nosakhare N Ekhator; Paul S Horn; Jeffrey R Strawn; Gerard Sanacora; Becky Kinkead; Lawrence H Price; Charles Nemeroff
Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression.
The American journal of psychiatry 2006;163(4):637-43.
2006: Gerard Sanacora; Lisa R Fenton; Madonna K Fasula; Douglas L Rothman; Yael Levin; John H Krystal; Graeme F Mason
Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy.
Biological psychiatry 2006;59(3):284-6.
2006: Daniel L Lafleur; Christopher Pittenger; Ben Kelmendi; Tom Gardner; Suzanne Wasylink; Robert T Malison; Gerard Sanacora; John H Krystal; Vladimir Coric
N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder.
Psychopharmacology 2006;184(2):254-6.
2006: Julie K Staley; Gerard Sanacora; Gilles Tamagnan; Paul K Maciejewski; Robert T Malison; Robert M Berman; Meena Vythilingam; Akira Kugaya; Ronald M Baldwin; John P Seibyl; Dennis Charney; Robert B Innis
Sex differences in diencephalon serotonin transporter availability in major depression.
Biological psychiatry 2006;59(1):40-7.
2005: Akira Kugaya; Gerard Sanacora
Beyond monoamines: glutamatergic function in mood disorders.
CNS spectrums 2005;10(10):808-19.
2005: Vladimir Coric; Sarper Taskiran; Christopher Pittenger; Suzanne Wasylink; Daniel H Mathalon; Gerald W Valentine; John Saksa; Yu-Te Wu; Ralitza Gueorguieva; Gerard Sanacora; Robert T Malison; John H Krystal
Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial.
Biological psychiatry 2005;58(5):424-8.
2005: Robert B Ostroff; Marbiela Gonzales; Gerard Sanacora
Antidepressant effect of ketamine during ECT.
The American journal of psychiatry 2005;162(7):1385-6.
2005: Steven F Kendell; John H Krystal; Gerard Sanacora
GABA and glutamate systems as therapeutic targets in depression and mood disorders.
Expert opinion on therapeutic targets 2005;9(1):153-68.
2005: C Neill Epperson; Stephanie O'Malley; Kathryn A Czarkowski; Ralitza Gueorguieva; Peter Jatlow; Gerard Sanacora; Douglas L Rothman; John H Krystal; Graeme F Mason
Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy.
Biological psychiatry 2005;57(1):44-8.
2004: Gerard Sanacora; Steven F Kendell; Lisa R Fenton; Vladimir Coric; John H Krystal
Riluzole augmentation for treatment-resistant depression.
The American journal of psychiatry 2004;161(11):2132.
2004: Akira Kugaya; Gerard Sanacora; Julie K Staley; Robert T Malison; Ali Bozkurt; Shaukat Khan; Amit Anand; Christopher H van Dyck; Ronald M Baldwin; John P Seibyl; Dennis Charney; Robert B Innis
Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.
Biological psychiatry 2004;56(7):497-502.
2004: Gerard Sanacora; Ralitza Gueorguieva; C Neill Epperson; Yu-Te Wu; Michael Appel; Douglas L Rothman; John H Krystal; Graeme F Mason
Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.
Archives of general psychiatry 2004;61(7):705-13.
2004: Gerard Sanacora; Robert M Berman; Angela Cappiello; Dan A Oren; Akira Kugaya; Nianjun Liu; Ralitza Gueorguieva; Donna Fasula; Dennis S Charney
Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(6):1166-71.
2004: Edward B Perry; Robert M Berman; Gerard Sanacora; Amit Anand; Kathleen Lynch-Colonese; Dennis S Charney
Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial.
The Journal of clinical psychiatry 2004;65(2):238-43.
2004: Jaakko Lappalainen; Gerard Sanacora; Henry R Kranzler; Robert T Malison; Ellen S Hibbard; Lawrence H Price; John H Krystal; Joel Gelernter
Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):81-6.
2003: Gerard Sanacora; Douglas L Rothman; Graeme Mason; John H Krystal
Clinical studies implementing glutamate neurotransmission in mood disorders.
Annals of the New York Academy of Sciences 2003;1003():292-308.
2003: Akira Kugaya; Gerard Sanacora; Nicolaas P L G Verhoeff; Masahiro Fujita; Graeme F Mason; Nicholas Seneca; Ali Bozkurt; Shaukat A Khan; Amit Anand; Kathleen Degen; Dennis S Charney; Sami S Zoghbi; Ronald M Baldwin; John P Seibyl; Robert B Innis
Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.
Biological psychiatry 2003;54(8):792-9.
2003: Gerard Sanacora; Graeme F Mason; Douglas L Rothman; Fahmeed Hyder; James J Ciarcia; Robert B Ostroff; Robert M Berman; John H Krystal
Increased cortical GABA concentrations in depressed patients receiving ECT.
The American journal of psychiatry 2003;160(3):577-9.
2002: Gerard Sanacora; Graeme F Mason; Douglas L Rothman; John H Krystal
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.
The American journal of psychiatry 2002;159(4):663-5.
2002: Robert M Berman; Gerard Sanacora; Amit Anand; Lisa M Roach; Madonna K Fasula; Catherine O Finkelstein; R Mathew Wachen; Dan A Oren; George R Heninger; Dennis S Charney
Monoamine depletion in unmedicated depressed subjects.
Biological psychiatry 2002;51(6):469-73.
2002: Joseph F Cubells; Lawrence H Price; Barnett S Meyers; george anderson; Cyrus Zabetian; George S Alexopoulos; J Craig Nelson; Gerard Sanacora; Paul Kirwin; Linda Carpenter; Robert T Malison; Joel Gelernter
Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression.
Biological psychiatry 2002;51(5):358-64.
2002: John H Krystal; Gerard Sanacora; H Blumberg; A Anand; Dennis S Charney; Gerard Marek; C Neill Epperson; Andrew Goddard; Graeme F Mason
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments.
Molecular psychiatry 2002;7 Suppl 1():S71-80.
2001: John H Krystal; D Cyril D'Souza; Gerard Sanacora; Andrew W Goddard; Dennis S Charney
Current perspectives on the pathophysiology of schizophrenia, depression, and anxiety disorders.
The Medical clinics of North America 2001;85(3):559-77.
2001: Andrew Chen; K H Shin; Ronald S Duman; Gerard Sanacora
ECS-Induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment.
The journal of ECT 2001;17(1):27-32.
2000: Robert M Berman; M Narasimhan; Gerard Sanacora; AP Miano; Ralph E Hoffman; X S Hu; Dennis S Charney; Nashaat N Boutros
A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression.
Biological psychiatry 2000;47(4):332-7.
2000: Gerard Sanacora; Graeme F Mason; J H Krystal
Impairment of GABAergic transmission in depression: new insights from neuroimaging studies.
Critical reviews in neurobiology 2000;14(1):23-45.
1999: Gerard Sanacora; Graeme F Mason; Douglas L Rothman; Kevin L Behar; Fahmeed Hyder; Ognen A C Petroff; Robert M Berman; Dennis S Charney; John H Krystal
Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.
Archives of general psychiatry 1999;56(11):1043-7.
1998: Robert T Malison; Lawrence H Price; Robert Berman; Christopher H van Dyck; GH Pelton; Linda Carpenter; Gerard Sanacora; M J Owens; Charles Nemeroff; N Rajeevan; Ronald M Baldwin; John P Seibyl; Robert B Innis; Dennis S Charney
Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography.
Biological psychiatry 1998;44(11):1090-8.