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Aziz Sancar

Research Profile

Physiology

DNA Repair

Chemicals & Drugs

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Anatomy

Hela Cells

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Publications

TOP 3
Nuri Ozturk; Russell N Van Gelder; Sarah J VanVickle-Chavez; Lakshmi Akileswaran; Aziz Sancar
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex.
Jin Hyup Lee; Nuri Ozturk; Shobhan Gaddameedhi; Rui Ye; Aziz Sancar
DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells.
Laura A Lindsey-Boltz; Joyce T Reardon; Marc S Wold; Aziz Sancar
In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling.

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All Publications

2013: Nuri Ozturk; Russell N Van Gelder; Sarah J VanVickle-Chavez; Lakshmi Akileswaran; Aziz Sancar
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(13):4980-5.
2013: Jin Hyup Lee; Nuri Ozturk; Shobhan Gaddameedhi; Rui Ye; Aziz Sancar
DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells.
Cancer research 2013;73(2):785-91.
2012: Laura A Lindsey-Boltz; Joyce T Reardon; Marc S Wold; Aziz Sancar
In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling.
The Journal of biological chemistry 2012;287(43):36123-31.
2012: Shobhan Gaddameedhi; Nuri Ozturk; Joyce T Reardon; Rui Ye; Aziz Sancar
Effect of circadian clock mutations on DNA damage response in mammalian cells.
Cell cycle (Georgetown, Tex.) 2012;11(18):3481-91.
2012: Michael G Kemp; Aziz Sancar
DNA excision repair: where do all the dimers go?
Cell cycle (Georgetown, Tex.) 2012;11(16):2997-3002.
2012: Michael G Kemp; Laura A Lindsey-Boltz; Joyce T Reardon; Aziz Sancar
Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair.
The Journal of biological chemistry 2012;287(27):22889-99.
2012: Zheyun Liu; Aziz Sancar; Chuang Tan; Lijuan Wang; Xunmin Guo; Ya-Ting Kao; Jiang Li; Dongping Zhong
Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyase.
Journal of the American Chemical Society 2012;134(19):8104-14.
2012: Ajna S Rivera; Aziz Sancar; Bernard M Degnan; Bryony Fahey; Nuri Ozturk; David Plachetzki; Todd H Oakley
Blue-light-receptive cryptochrome is expressed in a sponge eye lacking neurons and opsin.
The Journal of experimental biology 2012;215(Pt 8):1278-86.
2011: Shobhan Gaddameedhi; William K Kaufmann; Christopher P Selby; Robert C Smart; Aziz Sancar
Control of skin cancer by the circadian rhythm.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(46):18790-5.
2011: Zheyun Liu; Aziz Sancar; Chuang Tan; Lijuan Wang; Xunmin Guo; Ya-Ting Kao; Jiang Li; Dongping Zhong
Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(36):14831-6.
2011: Rui Ye; Christopher P Selby; Yunus Annayev; Nuri Ozturk; Aziz Sancar
Biochemical analysis of the canonical model for the mammalian circadian clock.
The Journal of biological chemistry 2011;286(29):25891-902.
2011: Jin Hyup Lee; Aziz Sancar
Regulation of apoptosis by the circadian clock through NF-kappaB signaling.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):12036-41.
2011: Jin Hyup Lee; Aziz Sancar
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(26):10668-72.
2011: Laura A Lindsey-Boltz; Aziz Sancar
Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
The Journal of biological chemistry 2011;286(22):19229-36.
2011: Michael G Kemp; Laura A Lindsey-Boltz; Aziz Sancar
The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.
The Journal of biological chemistry 2011;286(22):19237-46.
2011: Tae-Hong Kang; Joyce T Reardon; Aziz Sancar
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein.
Nucleic acids research 2011;39(8):3176-87.
2011: Shobhan Gaddameedhi; Aziz Sancar
Melanoma and DNA damage from a distance (farstander effect).
Pigment cell & melanoma research 2011;24(1):3-4.
2011: Nuri Ozturk; Christopher P Selby; Yunus Annayev; Dongping Zhong; Aziz Sancar
Reaction mechanism of Drosophila cryptochrome.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(2):516-21.
2011: Seçil Yilmaz; Aziz Sancar; Michael G Kemp
Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates.
PloS one 2011;6(7):e22986.
2010: Jiang Li; Zheyun Liu; Chuang Tan; Xunmin Guo; Lijuan Wang; Aziz Sancar; Dongping Zhong
Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyase.
Nature 2010;466(7308):887-890.
2010: Jun-Hyuk Choi; Laura A Lindsey-Boltz; Michael Kemp; Aaron C Mason; Marc S Wold; Aziz Sancar
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(31):13660-5.
2010: Aziz Sancar; Laura A Lindsey-Boltz; Tae-Hong Kang; Joyce T Reardon; Jin Hyup Lee; Nuri Ozturk
Circadian clock control of the cellular response to DNA damage.
FEBS letters 2010;584(12):2618-25.
2010: Shobhan Gaddameedhi; Michael G Kemp; Joyce T Reardon; Janiel M Shields; Stephanie L Smith-Roe; William K Kaufmann; Aziz Sancar
Similar nucleotide excision repair capacity in melanocytes and melanoma cells.
Cancer research 2010;70(12):4922-30.
2010: Michael G Kemp; Zafer Akan; Seçil Yilmaz; Mary Grillo; Stephanie L Smith-Roe; Tae-Hong Kang; Marila Cordeiro-Stone; William K Kaufmann; Robert T Abraham; Aziz Sancar; Keziban Unsal-Kaçmaz
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
The Journal of biological chemistry 2010;285(22):16562-71.
2010: Tae-Hong Kang; Laura A Lindsey-Boltz; Joyce T Reardon; Aziz Sancar
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):4890-5.
2010: Yiyong Liu; Yanan Fang; Hongbing Shao; Laura A Lindsey-Boltz; Aziz Sancar; Paul Modrich
Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.
The Journal of biological chemistry 2010;285(8):5974-82.
2010: Chih-Wei Chang; Lijun Guo; Ya-Ting Kao; Jiang Li; Chuang Tan; Tanping Li; Chaitanya Saxena; Zheyun Liu; Lijuan Wang; Aziz Sancar; Dongping Zhong
Ultrafast solvation dynamics at binding and active sites of photolyases.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):2914-9.
2010: Michael G Kemp; Aaron C Mason; Aura Carreira; Joyce T Reardon; Stuart J Haring; Gloria E. Borgstahl; Stephen C Kowalczykowski; Aziz Sancar; Marc S Wold
An alternative form of replication protein a expressed in normal human tissues supports DNA repair.
The Journal of biological chemistry 2010;285(7):4788-97.
2009: Laura A Lindsey-Boltz; Ozdemirhan Serçin; Jun-Hyuk Choi; Aziz Sancar
Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase.
The Journal of biological chemistry 2009;284(48):33107-14.
2009: Michael Kemp; Aziz Sancar
DNA distress: just ring 9-1-1.
Current biology : CB 2009;19(17):R733-4.
2009: Nuri Ozturk; Christopher P Selby; Sang-Hun Song; Rui Ye; Chuang Tan; Ya-Ting Kao; Dongping Zhong; Aziz Sancar
Comparative photochemistry of animal type 1 and type 4 cryptochromes.
Biochemistry 2009;48(36):8585-93.
2009: Li Li; Joana Perdigao; Anthony E Pegg; Yanbin Lao; Stephen S Hecht; Bruce R Lindgren; Joyce T Reardon; Aziz Sancar; Elizabeth V Wattenberg; Lisa A Peterson
The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines.
Chemical research in toxicology 2009;22(8):1464-72.
2009: Tae-Hong Kang; Aziz Sancar
Circadian regulation of DNA excision repair: implications for chrono-chemotherapy.
Cell cycle (Georgetown, Tex.) 2009;8(11):1665-7.
2009: Lata Balakrishnan; Patrick D Brandt; Laura A Lindsey-Boltz; Aziz Sancar; Robert A Bambara
Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex.
The Journal of biological chemistry 2009;284(22):15158-72.
2009: Jun-Hyuk Choi; Aziz Sancar; Laura A Lindsey-Boltz
The human ATR-mediated DNA damage checkpoint in a reconstituted system.
Methods (San Diego, Calif.) 2009;48(1):3-7.
2009: Jun-Hyuk Choi; Laura A Lindsey-Boltz; Aziz Sancar
Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA.
Nucleic acids research 2009;37(5):1501-9.
2009: Nuri Ozturk; Jin Hyup Lee; Shobhan Gaddameedhi; Aziz Sancar
Loss of cryptochrome reduces cancer risk in p53 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2841-6.
2009: Tae-Hong Kang; Joyce T Reardon; Michael Kemp; Aziz Sancar
Circadian oscillation of nucleotide excision repair in mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2864-7.
2008: Aziz Sancar
Structure and function of photolyase and in vivo enzymology: 50th anniversary.
The Journal of biological chemistry 2008;283(47):32153-7.
2008: Ya-Ting Kao; Chaitanya Saxena; Ting-Fang He; Lijun Guo; Lijuan Wang; Aziz Sancar; Dongping Zhong
Ultrafast dynamics of flavins in five redox states.
Journal of the American Chemical Society 2008;130(39):13132-9.
2008: Nuri Oztürk; Ya-Ting Kao; Christopher P Selby; I Halil Kavakli; Carrie L Partch; Dongping Zhong; Aziz Sancar
Purification and characterization of a type III photolyase from Caulobacter crescentus.
Biochemistry 2008;47(39):10255-61.
2008: Jonathan P Wisor; Ravi K Pasumarthi; Dmitry Gerashchenko; Carol Thompson; Sayan Pathak; Aziz Sancar; Paul Franken; Ed Lein; Thomas Kilduff
Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(28):7193-201.
2008: Katherine S Lovejoy; Ryan C Todd; Shuzhong Zhang; Michael S McCormick; J Alejandro D'Aquino; Joyce T Reardon; Aziz Sancar; Kathleen M Giacomini; Stephen J Lippard
cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(26):8902-7.
2008: Ya-Ting Kao; Chuang Tan; Sang-Hun Song; Nuri Oztürk; Jiang Li; Lijuan Wang; Aziz Sancar; Dongping Zhong
Ultrafast dynamics and anionic active states of the flavin cofactor in cryptochrome and photolyase.
Journal of the American Chemical Society 2008;130(24):7695-701.
2008: Nuri Oztürk; Sang-Hun Song; Christopher P Selby; Aziz Sancar
Animal type 1 cryptochromes. Analysis of the redox state of the flavin cofactor by site-directed mutagenesis.
The Journal of biological chemistry 2008;283(6):3256-63.
2008: Aziz Sancar
The intelligent clock and the Rube Goldberg clock.
Nature structural & molecular biology 2008;15(1):23-4.
2007: Kevin J Kesseler; William K Kaufmann; Joyce T Reardon; Timothy C Elston; Aziz Sancar
A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading.
Journal of theoretical biology 2007;249(2):361-75.
2007: Jun-Hyuk Choi; Laura A Lindsey-Boltz; Aziz Sancar
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(33):13301-6.
2007: Laura A Lindsey-Boltz; Aziz Sancar
RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage?
Proceedings of the National Academy of Sciences of the United States of America 2007;104(33):13213-4.
2007: Sang-Hun Song; Nuri Oztürk; Tracy R Denaro; Nezahat Ozlem Arat; Ya-Ting Kao; Haisun Zhu; Dongping Zhong; Steven M Reppert; Aziz Sancar
Formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly.
The Journal of biological chemistry 2007;282(24):17608-12.
2007: Keziban Unsal-Kaçmaz; Paul Chastain; Pingping Qu; Parviz Minoo; Marila Cordeiro-Stone; Aziz Sancar; William K Kaufmann
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement.
Molecular and cellular biology 2007;27(8):3131-42.
2007: Timothy P Heffernan; Keziban Unsal-Kaçmaz; Alexandra N Heinloth; Dennis A Simpson; Richard S Paules; Aziz Sancar; Marila Cordeiro-Stone; William K Kaufmann
Cdc7-Dbf4 and the human S checkpoint response to UVC.
The Journal of biological chemistry 2007;282(13):9458-68.
2007: Olga Sokolova; Christine Cecala; Anand Gopal; Frank Cortazar; Carla McDowell-Buchanan; Aziz Sancar; Yvonne M Gindt; Johannes P M Schelvis
Resonance Raman spectroscopic investigation of the light-harvesting chromophore in escherichia coli photolyase and Vibrio cholerae cryptochrome-1.
Biochemistry 2007;46(12):3673-81.
2007: N Oztürk; S-H Song; Sezgin Ozgür; Christopher P Selby; L Morrison; C Partch; Dongping Zhong; Aziz Sancar
Structure and function of animal cryptochromes.
Cold Spring Harbor symposia on quantitative biology 2007;72():119-31.
2007: Ya-Ting Kao; Chaitanya Saxena; Lijuan Wang; Aziz Sancar; Dongping Zhong
Femtochemistry in enzyme catalysis: DNA photolyase.
Cell biochemistry and biophysics 2007;48(1):32-44.
2006: Christopher P Selby; Aziz Sancar
A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17696-700.
2006: Sezgin Ozgür; Aziz Sancar
Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes.
Biochemistry 2006;45(44):13369-74.
2006: Wensheng Wang; Laura A Lindsey-Boltz; Aziz Sancar; Robert A Bambara
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex.
The Journal of biological chemistry 2006;281(30):20865-72.
2006: Carrie L Partch; Katherine F Shields; Carol Thompson; Christopher P Selby; Aziz Sancar
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10467-72.
2006: Joyce T Reardon; Yuan Cheng; Aziz Sancar
Repair of DNA-protein cross-links in mammalian cells.
Cell cycle (Georgetown, Tex.) 2006;5(13):1366-70.
2006: Joyce T Reardon; Aziz Sancar
Repair of DNA-polypeptide crosslinks by human excision nuclease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):4056-61.
2006: Reade B Roberts; Carol Thompson; Daekee Lee; Richard W Mankinen; Aziz Sancar; David Threadgill
Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice.
Journal of circadian rhythms 2006;4():15.
2006: Joyce T Reardon; Aziz Sancar
Purification and characterization of Escherichia coli and human nucleotide excision repair enzyme systems.
Methods in enzymology 2006;408():189-213.
2006: Gwendolyn B Sancar; Aziz Sancar
Purification and characterization of DNA photolyases.
Methods in enzymology 2006;408():121-56.
2006: Guochun Jiang; Aziz Sancar
Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences.
Molecular and cellular biology 2006;26(1):39-49.
2005: Ya-Ting Kao; Chaitanya Saxena; Lijuan Wang; Aziz Sancar; Dongping Zhong
Direct observation of thymine dimer repair in DNA by photolyase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16128-32.
2005: Gülnihal Kulaksiz; Joyce T Reardon; Aziz Sancar
Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties.
Molecular and cellular biology 2005;25(22):9784-92.
2005: Carrie L Partch; Aziz Sancar
Photochemistry and photobiology of cryptochrome blue-light photopigments: the search for a photocycle.
Photochemistry and photobiology 2005;81(6):1291-304.
2005: Maria C DeRosa; Aziz Sancar; Jacqueline K Barton
Electrically monitoring DNA repair by photolyase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10788-92.
2005: Michele A Gauger; Aziz Sancar
Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer.
Cancer research 2005;65(15):6828-34.
2005: Chaitanya Saxena; Haiyu Wang; I Halil Kavakli; Aziz Sancar; Dongping Zhong
Ultrafast dynamics of resonance energy transfer in cryptochrome.
Journal of the American Chemical Society 2005;127(22):7984-5.
2005: Keziban Unsal-Kaçmaz; Thomas E Mullen; William K Kaufmann; Aziz Sancar
Coupling of human circadian and cell cycles by the timeless protein.
Molecular and cellular biology 2005;25(8):3109-16.
2005: Carrie L Partch; Michael W Clarkson; Sezgin Ozgür; Andrew L Lee; Aziz Sancar
Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor.
Biochemistry 2005;44(10):3795-805.
2005: Stephanie Q Hutsell; Aziz Sancar
Nucleotide excision repair, oxidative damage, DNA sequence polymorphisms, and cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1355-7.
2005: Haiyu Wang; Chaitanya Saxena; Donghui Quan; Aziz Sancar; Dongping Zhong
Femtosecond dynamics of flavin cofactor in DNA photolyase: radical reduction, local solvation, and charge recombination.
The journal of physical chemistry. B 2005;109(4):1329-33.
2005: Joyce T Reardon; Aziz Sancar
Nucleotide excision repair.
Progress in nucleic acid research and molecular biology 2005;79():183-235.
2005: Carrie L Partch; Aziz Sancar
Cryptochromes and circadian photoreception in animals.
Methods in enzymology 2005;393():726-45.
2004: I Halil Kavakli; Aziz Sancar
Analysis of the role of intraprotein electron transfer in photoreactivation by DNA photolyase in vivo.
Biochemistry 2004;43(48):15103-10.
2004: Carol Thompson; Christopher P Selby; Russell N Van Gelder; William S Blaner; Janet Lee; Loredana Quadro; Katherine Lai; Max E Gottesman; Aziz Sancar
Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice.
Journal of biological rhythms 2004;19(6):504-17.
2004: Wensheng Wang; Patrick D Brandt; Marie L Rossi; Laura A Lindsey-Boltz; Vladimir N Podust; Ellen Fanning; Aziz Sancar; Robert A Bambara
The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16762-7.
2004: Funda Sar; Laura A Lindsey-Boltz; Deepa Subramanian; Deborah L Croteau; Stephanie Q Hutsell; Jack D Griffith; Aziz Sancar
Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures.
The Journal of biological chemistry 2004;279(38):39289-95.
2004: Aziz Sancar
Regulation of the mammalian circadian clock by cryptochrome.
The Journal of biological chemistry 2004;279(33):34079-82.
2004: Carol Thompson; Christopher P Selby; Carrie L Partch; David T Plante; Randy J Thresher; Francisco Araujo; Aziz Sancar
Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction.
Brain research. Molecular brain research 2004;122(2):158-66.
2004: Keziban Unsal-Kaçmaz; Aziz Sancar
Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities.
Molecular and cellular biology 2004;24(3):1292-300.
2004: Joyce T Reardon; Aziz Sancar
Thermodynamic cooperativity and kinetic proofreading in DNA damage recognition and repair.
Cell cycle (Georgetown, Tex.) 2004;3(2):141-4.
2004: Aziz Sancar
Photolyase and cryptochrome blue-light photoreceptors.
Advances in protein chemistry 2004;69():73-100.
2004: Aziz Sancar; Joyce T Reardon
Nucleotide excision repair in E. coli and man.
Advances in protein chemistry 2004;69():43-71.
2004: Laura A Lindsey-Boltz; Eric M Wauson; Lee M Graves; Aziz Sancar
The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD.
Nucleic acids research 2004;32(15):4524-30.
2004: Aziz Sancar; Laura A Lindsey-Boltz; Keziban Unsal-Kaçmaz; Stuart Linn
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
Annual review of biochemistry 2004;73():39-85.
2003: Joyce T Reardon; Aziz Sancar
Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease.
Genes & development 2003;17(20):2539-51.
2003: Erin N Worthington; I Halil Kavakli; Gloria Berrocal Tito; Bruce E Bondo; Aziz Sancar
Purification and characterization of three members of the photolyase/cryptochrome family blue-light photoreceptors from Vibrio cholerae.
The Journal of biological chemistry 2003;278(40):39143-54.
2003: Carol Thompson; Catherine Bowes Rickman; Steven J Shaw; Jessica N Ebright; Una Kelly; Aziz Sancar; Dennis W Rickman
Expression of the blue-light receptor cryptochrome in the human retina.
Investigative ophthalmology & visual science 2003;44(10):4515-21.
2003: Müge Oğrünç; Aziz Sancar
Identification and characterization of human MUS81-MMS4 structure-specific endonuclease.
The Journal of biological chemistry 2003;278(24):21715-20.
2003: Dong Wang; Ryujiro Hara; Gitanjali Singh; Aziz Sancar; Stephen J Lippard
Nucleotide excision repair from site-specifically platinum-modified nucleosomes.
Biochemistry 2003;42(22):6747-53.
2003: Aziz Sancar
Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors.
Chemical reviews 2003;103(6):2203-37.
2003: Ryujiro Hara; Aziz Sancar
Effect of damage type on stimulation of human excision nuclease by SWI/SNF chromatin remodeling factor.
Molecular and cellular biology 2003;23(12):4121-5.
2003: Sezgin Ozgur; Aziz Sancar
Purification and properties of human blue-light photoreceptor cryptochrome 2.
Biochemistry 2003;42(10):2926-32.
2003: Vladimir P Bermudez; Laura A Lindsey-Boltz; Anthony J Cesare; Yoshimasa Maniwa; Jack D Griffith; Jerard Hurwitz; Aziz Sancar
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1633-8.
2003: Russell N Van Gelder; Aziz Sancar
Cryptochromes and inner retinal non-visual irradiance detection.
Novartis Foundation symposium 2003;253():31-42; discussion 42-55, 102-9, 281-4.
2003: Christopher P Selby; Aziz Sancar
Characterization of transcription-repair coupling factors in E. coli and humans.
Methods in enzymology 2003;371():300-24.
2002: Jonathan P Wisor; Bruce F O'Hara; Akira Terao; Chris P Selby; Thomas Kilduff; Aziz Sancar; Dale M Edgar; Paul Franken
A role for cryptochromes in sleep regulation.
BMC neuroscience 2002;3():20.
2002: Carol Thompson; Aziz Sancar
Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock.
Oncogene 2002;21(58):9043-56.
2002: I Halil Kavakli; Aziz Sancar
Circadian photoreception in humans and mice.
Molecular interventions 2002;2(8):484-92.
2002: Ryujiro Hara; Aziz Sancar
The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.
Molecular and cellular biology 2002;22(19):6779-87.
2002: Joyce T Reardon; Aziz Sancar
Molecular anatomy of the human excision nuclease assembled at sites of DNA damage.
Molecular and cellular biology 2002;22(16):5938-45.
2002: Russell N Van Gelder; Therese M Gibler; Daniel Tu; Kris Embry; Christopher P Selby; Carol Thompson; Aziz Sancar
Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms.
Journal of neurogenetics 2002;16(3):181-203.
2002: Nicolas Cermakian; Matthew P Pando; Carol Thompson; Anna B Pinchak; Christopher P Selby; LAURA GUTIERREZ; Dan E Wells; Gregory M Cahill; Aziz Sancar; Paolo Sassone-Corsi
Light induction of a vertebrate clock gene involves signaling through blue-light receptors and MAP kinases.
Current biology : CB 2002;12(10):844-8.
2002: Keziban Unsal-Kaçmaz; Alexander M Makhov; Jack D Griffith; Aziz Sancar
Preferential binding of ATR protein to UV-damaged DNA.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6673-8.
2002: Jack D Griffith; Laura A Lindsey-Boltz; Aziz Sancar
Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy.
The Journal of biological chemistry 2002;277(18):15233-6.
2002: Mitsuo Wakasugi; Aki Kawashima; Hiroshi Morioka; Stuart Linn; Aziz Sancar; Toshio Mori; Osamu Nikaido; Tsukasa Matsunaga
DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair.
The Journal of biological chemistry 2002;277(3):1637-40.
2001: James W George; Edmund P Salazar; Maaike P G Vreeswijk; Jane Lamerdin; Joyce T Reardon; Malgorzata Z Zdzienicka; Aziz Sancar; Saloumeh Kadkhodayan; Robert S Tebbs; Leon H F Mullenders; Larry H Thompson
Restoration of nucleotide excision repair in a helicase-deficient XPD mutant from intragenic suppression by a trichothiodystrophy mutation.
Molecular and cellular biology 2001;21(21):7355-65.
2001: Laura A Lindsey-Boltz; Vladimir P Bermudez; Jerard Hurwitz; Aziz Sancar
Purification and characterization of human DNA damage checkpoint Rad complexes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11236-41.
2001: Carol Thompson; William S Blaner; Russell N Van Gelder; Katherine Lai; Loredana Quadro; Vittorio Colantuoni; Max E Gottesman; Aziz Sancar
Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11708-13.
2001: M E Branum; Joyce T Reardon; Aziz Sancar
DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutations.
The Journal of biological chemistry 2001;276(27):25421-6.
2000: Christopher P Selby; Carol Thompson; T M Schmitz; Russell N Van Gelder; Aziz Sancar
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14697-702.
2000: Ryujiro Hara; J Mo; Aziz Sancar
DNA damage in the nucleosome core is refractory to repair by human excision nuclease.
Molecular and cellular biology 2000;20(24):9173-81.
2000: Shinya Shibutani; J T Reardon; Naomi Suzuki; Aziz Sancar
Excision of tamoxifen-DNA adducts by the human nucleotide excision repair system.
Cancer research 2000;60(10):2607-10.
2000: D Mu; T Bessho; Lubomir V Nechev; D J Chen; Thomas Harris; J E Hearst; Aziz Sancar
DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts.
Molecular and cellular biology 2000;20(7):2446-54.
2000: T Bessho; Aziz Sancar
Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease.
The Journal of biological chemistry 2000;275(11):7451-4.
2000: Aziz Sancar; Carol Thompson; Randy J Thresher; F Araujo; J Mo; S Ozgur; E Vagas; L Dawut; Christopher P Selby
Photolyase/cryptochrome family blue-light photoreceptors use light energy to repair DNA or set the circadian clock.
Cold Spring Harbor symposia on quantitative biology 2000;65():157-71.
2000: Aziz Sancar
Cryptochrome: the second photoactive pigment in the eye and its role in circadian photoreception.
Annual review of biochemistry 2000;69():31-67.
1999: Christopher W M Kay; R Feicht; K Schulz; P Sadewater; Aziz Sancar; Adelbert Bacher; Klaus Möbius; Gerald Richter; Stefan Weber
EPR, ENDOR, and TRIPLE resonance spectroscopy on the neutral flavin radical in Escherichia coli DNA photolyase.
Biochemistry 1999;38(51):16740-8.
1999: Martha Hotz Vitaterna; Christopher P Selby; T Todo; H Niwa; Carol Thompson; Ethan M Fruechte; K Hitomi; Randy J Thresher; T Ishikawa; J Miyazaki; Joseph S Takahashi; Aziz Sancar
Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):12114-9.
1999: Ryujiro Hara; Christopher P Selby; M Liu; D H Price; Aziz Sancar
Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimer.
The Journal of biological chemistry 1999;274(35):24779-86.
1999: Y Miyamoto; Aziz Sancar
Circadian regulation of cryptochrome genes in the mouse.
Brain research. Molecular brain research 1999;71(2):238-43.
1999: Joyce T Reardon; Alexandra Vaisman; Stephen G Chaney; Aziz Sancar
Efficient nucleotide excision repair of cisplatin, oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts.
Cancer research 1999;59(16):3968-71.
1999: M Wakasugi; Aziz Sancar
Order of assembly of human DNA repair excision nuclease.
The Journal of biological chemistry 1999;274(26):18759-68.
1999: Yvonne M Gindt; E Vollenbroek; KL Westphal; H Sackett; Aziz Sancar; Gerald T Babcock
Origin of the transient electron paramagnetic resonance signals in DNA photolyase.
Biochemistry 1999;38(13):3857-66.
1999: Aziz Sancar
Excision repair invades the territory of mismatch repair.
Nature genetics 1999;21(3):247-9.
1999: C Petit; Aziz Sancar
Nucleotide excision repair: from E. coli to man.
Biochimie 1999;81(1-2):15-25.
1999: Christopher P Selby; Aziz Sancar
A third member of the photolyase/blue-light photoreceptor family in Drosophila: a putative circadian photoreceptor.
Photochemistry and photobiology 1999;69(1):105-7.
1998: Randy J Thresher; Martha Hotz Vitaterna; Y Miyamoto; A Kazantsev; DS Hsu; C Petit; Christopher P Selby; L Dawut; Oliver Smithies; Joseph S Takahashi; Aziz Sancar
Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.
Science (New York, N.Y.) 1998;282(5393):1490-4.
1998: Sikandar G Khan; Harvey L Levy; R Legerski; Elizabeth J Quackenbush; J T Reardon; Steffen Emmert; Aziz Sancar; L Li; Thomas D Schneider; James E Cleaver; Kenneth H Kraemer
Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia.
The Journal of investigative dermatology 1998;111(5):791-6.
1998: M Ogrünç; Donald F Becker; Stephen W Ragsdale; Aziz Sancar
Nucleotide excision repair in the third kingdom.
Journal of bacteriology 1998;180(21):5796-8.
1998: M Wakasugi; Aziz Sancar
Assembly, subunit composition, and footprint of human DNA repair excision nuclease.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6669-74.
1998: Y Miyamoto; Aziz Sancar
Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6097-102.
1998: A Kazantsev; S K Bullock; Aziz Sancar; Marila Cordeiro-Stone
Generation and characterization of an immortal cell line of xeroderma pigmentosum group E.
Mutation research 1998;407(1):55-65.
1997: X Zhao; J Liu; DS Hsu; S Zhao; J S Taylor; Aziz Sancar
Reaction mechanism of (6-4) photolyase.
The Journal of biological chemistry 1997;272(51):32580-90.
1997: T Bessho; D Mu; Aziz Sancar
Initiation of DNA interstrand cross-link repair in humans: the nucleotide excision repair system makes dual incisions 5' to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free strand.
Molecular and cellular biology 1997;17(12):6822-30.
1997: D Mu; M Wakasugi; DS Hsu; Aziz Sancar
Characterization of reaction intermediates of human excision repair nuclease.
The Journal of biological chemistry 1997;272(46):28971-9.
1997: S Zhao; Aziz Sancar
Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity.
Photochemistry and photobiology 1997;66(5):727-31.
1997: Christopher P Selby; Aziz Sancar
Cockayne syndrome group B protein enhances elongation by RNA polymerase II.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11205-9.
1997: Joyce T Reardon; T Bessho; HC Kung; Philip H Bolton; Aziz Sancar
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9463-8.
1997: M Wakasugi; Joyce T Reardon; Aziz Sancar
The non-catalytic function of XPG protein during dual incision in human nucleotide excision repair.
The Journal of biological chemistry 1997;272(25):16030-4.
1997: B Perelman; N Dafni; T Naiman; D Eli; M Yaakov; T L Feng; S Sinha; Günther Weber; S Khodaei; Aziz Sancar; Iris Dotan; Dan Canaani
Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus.
Genomics 1997;41(3):397-405.
1997: D Mu; Aziz Sancar
Model for XPC-independent transcription-coupled repair of pyrimidine dimers in humans.
The Journal of biological chemistry 1997;272(12):7570-3.
1997: Joyce T Reardon; Larry H Thompson; Aziz Sancar
Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity.
Nucleic acids research 1997;25(5):1015-21.
1997: Christopher P Selby; Ronny Drapkin; D Reinberg; Aziz Sancar
RNA polymerase II stalled at a thymine dimer: footprint and effect on excision repair.
Nucleic acids research 1997;25(4):787-93.
1997: T Bessho; Aziz Sancar; Larry H Thompson; M P Thelen
Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex.
The Journal of biological chemistry 1997;272(6):3833-7.
1997: D Mu; M Tursun; D R Duckett; JT Drummond; Paul Modrich; Aziz Sancar
Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems.
Molecular and cellular biology 1997;17(2):760-9.
1997: Christopher P Selby; Aziz Sancar
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II.
The Journal of biological chemistry 1997;272(3):1885-90.
1997: D Mu; Aziz Sancar
DNA excision repair assays.
Progress in nucleic acid research and molecular biology 1997;56():63-81.
1996: D S Hsu; X Zhao; Shaying Zhao; A Kazantsev; R P Wang; Takeshi Todo; YF Wei; Aziz Sancar
Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.
Biochemistry 1996;35(44):13871-7.
1996: K W Brookman; Jane Lamerdin; Michael P Thelen; M Hwang; J T Reardon; Aziz Sancar; ZQ Zhou; Christi A Walter; C N Parris; Larry H Thompson
ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs.
Molecular and cellular biology 1996;16(11):6553-62.
1996: Stephen G Chaney; Aziz Sancar
DNA repair: enzymatic mechanisms and relevance to drug response.
Journal of the National Cancer Institute 1996;88(19):1346-60.
1996: Joyce T Reardon; D Mu; Aziz Sancar
Overproduction, purification, and characterization of the XPC subunit of the human DNA repair excision nuclease.
The Journal of biological chemistry 1996;271(32):19451-6.
1996: Deborah B Zamble; D Mu; Joyce T Reardon; Aziz Sancar; Stephen J Lippard
Repair of cisplatin--DNA adducts by the mammalian excision nuclease.
Biochemistry 1996;35(31):10004-13.
1996: Joyce T Reardon; H Ge; E Gibbs; Aziz Sancar; Jerard Hurwitz; Z Q Pan
Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6482-7.
1996: D R Duckett; JT Drummond; AI Murchie; J T Reardon; Aziz Sancar; David M J Lilley; Paul Modrich
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6443-7.
1996: ST Kim; K Malhotra; H Ryo; Aziz Sancar; Takeshi Todo
Purification and characterization of Drosophila melanogaster photolyase.
Mutation research 1996;363(2):97-104.
1996: A Kazantsev; D Mu; A F Nichols; X Zhao; Stuart Linn; Aziz Sancar
Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):5014-8.
1996: T Matsunaga; C H Park; T Bessho; D Mu; Aziz Sancar
Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease.
The Journal of biological chemistry 1996;271(19):11047-50.
1996: D Mu; D S Hsu; Aziz Sancar
Reaction mechanism of human DNA repair excision nuclease.
The Journal of biological chemistry 1996;271(14):8285-94.
1996: Aziz Sancar
No "End of History" for photolyases.
Science (New York, N.Y.) 1996;272(5258):48-9.
1996: ST Kim; K Malhotra; J S Taylor; Aziz Sancar
Purification and partial characterization of (6-4) photoproduct DNA photolyase from Xenopus laevis.
Photochemistry and photobiology 1996;63(3):292-5.
1996: Aziz Sancar
DNA excision repair.
Annual review of biochemistry 1996;65():43-81.
1995: ZAHIDE OZER; Joyce T Reardon; D S Hsu; K Malhotra; Aziz Sancar
The other function of DNA photolyase: stimulation of excision repair of chemical damage to DNA.
Biochemistry 1995;34(49):15886-9.
1995: A Kazantsev; Aziz Sancar
Does the p53 up-regulated Gadd45 protein have a role in excision repair?
Science (New York, N.Y.) 1995;270(5238):1003-4; author reply 1005-6.
1995: C H Park; T Bessho; T Matsunaga; Aziz Sancar
Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease.
The Journal of biological chemistry 1995;270(39):22657-60.
1995: Z Q Pan; Joyce T Reardon; L Li; Flores-Rozas Hernan; R Legerski; Aziz Sancar; Jerard Hurwitz
Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21.
The Journal of biological chemistry 1995;270(37):22008-16.
1995: T Matsunaga; D Mu; C H Park; Joyce T Reardon; Aziz Sancar
Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies.
The Journal of biological chemistry 1995;270(35):20862-9.
1995: Aziz Sancar
Excision repair in mammalian cells.
The Journal of biological chemistry 1995;270(27):15915-8.
1995: H W Park; S T Kim; Aziz Sancar; Johann Deisenhofer
Crystal structure of DNA photolyase from Escherichia coli.
Science (New York, N.Y.) 1995;268(5219):1866-72.
1995: K Malhotra; ST Kim; A Batschauer; L Dawut; Aziz Sancar
Putative blue-light photoreceptors from Arabidopsis thaliana and Sinapis alba with a high degree of sequence homology to DNA photolyase contain the two photolyase cofactors but lack DNA repair activity.
Biochemistry 1995;34(20):6892-9.
1995: Z Q Pan; C H Park; A A Amin; Jerard Hurwitz; Aziz Sancar
Phosphorylated and unphosphorylated forms of human single-stranded DNA-binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4636-40.
1995: D S Hsu; ST Kim; Q Sun; Aziz Sancar
Structure and function of the UvrB protein.
The Journal of biological chemistry 1995;270(14):8319-27.
1995: C H Park; D Mu; Joyce T Reardon; Aziz Sancar
The general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factor.
The Journal of biological chemistry 1995;270(9):4896-902.
1995: Christopher P Selby; Aziz Sancar
Structure and function of transcription-repair coupling factor. II. Catalytic properties.
The Journal of biological chemistry 1995;270(9):4890-5.
1995: Christopher P Selby; Aziz Sancar
Structure and function of transcription-repair coupling factor. I. Structural domains and binding properties.
The Journal of biological chemistry 1995;270(9):4882-9.
1995: D Mu; C H Park; T Matsunaga; D S Hsu; Joyce T Reardon; Aziz Sancar
Reconstitution of human DNA repair excision nuclease in a highly defined system.
The Journal of biological chemistry 1995;270(6):2415-8.
1995: ST Kim; Aziz Sancar
Photorepair of nonadjacent pyrimidine dimers by DNA photolyase.
Photochemistry and photobiology 1995;61(2):171-4.
1995: Aziz Sancar
DNA repair in humans.
Annual review of genetics 1995;29():69-105.
1995: ST Kim; P F Heelis; Aziz Sancar
Role of tryptophans in substrate binding and catalysis by DNA photolyase.
Methods in enzymology 1995;258():319-43.
1994: Aziz Sancar
Mechanisms of DNA excision repair.
Science (New York, N.Y.) 1994;266(5193):1954-6.
1994: J C Huang; D S Hsu; A Kazantsev; Aziz Sancar
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12213-7.
1994: D Mu; E Bertrand-Burggraf; J C Huang; Robert Fuchs; Aziz Sancar; B P Fuchs
Human and E.coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct.
Nucleic acids research 1994;22(23):4869-71.
1994: J C Huang; Deborah B Zamble; Joyce T Reardon; Stephen J Lippard; Aziz Sancar
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10394-8.
1994: D S Hsu; M Takahashi; E Delagoutte; E Bertrand-Burggraf; Y H Wang; B Norden; Robert Fuchs; Jack D Griffith; Aziz Sancar
Flow linear dichroism and electron microscopic analysis of protein-DNA complexes of a mutant UvrB protein that binds to but cannot kink DNA.
Journal of molecular biology 1994;241(5):645-50.
1994: Christopher P Selby; Aziz Sancar
Mechanisms of transcription-repair coupling and mutation frequency decline.
Microbiological reviews 1994;58(3):317-29.
1994: K Malhotra; ST Kim; Aziz Sancar
Characterization of a medium wavelength type DNA photolyase: purification and properties of photolyase from Bacillus firmus.
Biochemistry 1994;33(29):8712-8.
1994: J C Huang; Aziz Sancar
Determination of minimum substrate size for human excinuclease.
The Journal of biological chemistry 1994;269(29):19034-40.
1994: Larry H Thompson; K W Brookman; C A Weber; Edmund P Salazar; J T Reardon; Aziz Sancar; Z Deng; M J Siciliano
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):6855-9.
1994: C H Park; Aziz Sancar
Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):5017-21.
1994: Ronny Drapkin; J T Reardon; Athar I Ansari; J C Huang; L Zawel; K Ahn; Aziz Sancar; Danny Reinberg
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II.
Nature 1994;368(6473):769-72.
1994: Ronny Drapkin; Aziz Sancar; Danny Reinberg
Where transcription meets repair.
Cell 1994;77(1):9-12.
1994: ST Kim; K Malhotra; C A Smith; J S Taylor; Aziz Sancar
Characterization of (6-4) photoproduct DNA photolyase.
The Journal of biological chemistry 1994;269(11):8535-40.
1994: Aziz Sancar
Structure and function of DNA photolyase.
Biochemistry 1994;33(1):2-9.
1993: Christopher P Selby; Aziz Sancar
Transcription-repair coupling and mutation frequency decline.
Journal of bacteriology 1993;175(23):7509-14.
1993: C H Park; Aziz Sancar
Reconstitution of mammalian excision repair activity with mutant cell-free extracts and XPAC and ERCC1 proteins expressed in Escherichia coli.
Nucleic acids research 1993;21(22):5110-6.
1993: Joyce T Reardon; A F Nichols; S Keeney; C A Smith; J S Taylor; Stuart Linn; Aziz Sancar
Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T.
The Journal of biological chemistry 1993;268(28):21301-8.
1993: ST Kim; Aziz Sancar; C Essenmacher; G T Babcock
Time-resolved EPR studies with DNA photolyase: excited-state FADH0 abstracts an electron from Trp-306 to generate FADH-, the catalytically active form of the cofactor.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8023-7.
1993: ST Kim; K Malhotra; C A Smith; J S Taylor; Aziz Sancar
DNA photolyase repairs the trans-syn cyclobutane thymine dimer.
Biochemistry 1993;32(28):7065-8.
1993: H W Park; Aziz Sancar; Johann Deisenhofer
Crystallization and preliminary crystallographic analysis of Escherichia coli DNA photolyase.
Journal of molecular biology 1993;231(4):1122-5.
1993: S S Sastry; H P Spielmann; Q S Hoang; A M Phillips; Aziz Sancar; J E Hearst
Laser-induced protein-DNA cross-links via psoralen furanside monoadducts.
Biochemistry 1993;32(21):5526-38.
1993: Y F Li; ST Kim; Aziz Sancar
Evidence for lack of DNA photoreactivating enzyme in humans.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4389-93.
1993: D L Svoboda; C A Smith; J S Taylor; Aziz Sancar
Effect of sequence, adduct type, and opposing lesions on the binding and repair of ultraviolet photodamage by DNA photolyase and (A)BC excinuclease.
The Journal of biological chemistry 1993;268(14):10694-700.
1993: Aziz Sancar; M S Tang
Nucleotide excision repair.
Photochemistry and photobiology 1993;57(5):905-21.
1993: ST Kim; Aziz Sancar
Photochemistry, photophysics, and mechanism of pyrimidine dimer repair by DNA photolyase.
Photochemistry and photobiology 1993;57(5):895-904.
1993: Christopher P Selby; Aziz Sancar
Molecular mechanism of transcription-repair coupling.
Science (New York, N.Y.) 1993;260(5104):53-8.
1993: Aziz Sancar; J E Hearst
Molecular matchmakers.
Science (New York, N.Y.) 1993;259(5100):1415-20.
1993: P F Heelis; ST Kim; T Okamura; Aziz Sancar
The photo repair of pyrimidine dimers by DNA photolyase and model systems.
Journal of photochemistry and photobiology. B, Biology 1993;17(3):219-28.
1993: D L Svoboda; J S Taylor; J E Hearst; Aziz Sancar
DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes.
The Journal of biological chemistry 1993;268(3):1931-6.
1993: Joyce T Reardon; L H Thompson; Aziz Sancar
Excision repair in man and the molecular basis of xeroderma pigmentosum syndrome.
Cold Spring Harbor symposia on quantitative biology 1993;58():605-17.
1992: P F Heelis; Aziz Sancar; T Okamura
Excited quartet states in DNA photolyase.
Journal of photochemistry and photobiology. B, Biology 1992;16(3-4):387-90.
1992: ST Kim; P F Heelis; Aziz Sancar
Energy transfer (deazaflavin-->FADH2) and electron transfer (FADH2-->T <> T) kinetics in Anacystis nidulans photolyase.
Biochemistry 1992;31(45):11244-8.
1992: J J Lin; A M Phillips; J E Hearst; Aziz Sancar
Active site of (A)BC excinuclease. II. Binding, bending, and catalysis mutants of UvrB reveal a direct role in 3' and an indirect role in 5' incision.
The Journal of biological chemistry 1992;267(25):17693-700.
1992: J J Lin; Aziz Sancar
Active site of (A)BC excinuclease. I. Evidence for 5' incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residues.
The Journal of biological chemistry 1992;267(25):17688-92.
1992: K Malhotra; ST Kim; C Walsh; Aziz Sancar
Roles of FAD and 8-hydroxy-5-deazaflavin chromophores in photoreactivation by Anacystis nidulans DNA photolyase.
The Journal of biological chemistry 1992;267(22):15406-11.
1992: J J Lin; Aziz Sancar
(A)BC excinuclease: the Escherichia coli nucleotide excision repair enzyme.
Molecular microbiology 1992;6(16):2219-24.
1992: P F Heelis; D J Deeble; ST Kim; Aziz Sancar
Splitting of cis-syn cyclobutane thymine-thymine dimers by radiolysis and its relevance to enzymatic photoreactivation.
International journal of radiation biology 1992;62(2):137-43.
1992: Q Shi; Randy J Thresher; Aziz Sancar; J Griffith
Electron microscopic study of (A)BC excinuclease. DNA is sharply bent in the UvrB-DNA complex.
Journal of molecular biology 1992;226(2):425-32.
1992: A F Nichols; Aziz Sancar
Purification of PCNA as a nucleotide excision repair protein.
Nucleic acids research 1992;20(13):2441-6.
1992: Aziz Sancar
In vitro characterization of repair synthesis initiated by T4 endonuclease V on a synthetic DNA substrate.
Indian journal of biochemistry & biophysics 1992;29(3):227-30.
1992: J C Huang; D L Svoboda; Joyce T Reardon; Aziz Sancar
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3664-8.
1992: K Malhotra; M Baer; Y F Li; G B Sancar; Aziz Sancar
Identification of chromophore binding domains of yeast DNA photolyase.
The Journal of biological chemistry 1992;267(5):2909-14.
1992: ST Kim; Y F Li; Aziz Sancar
The third chromophore of DNA photolyase: Trp-277 of Escherichia coli DNA photolyase repairs thymine dimers by direct electron transfer.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(3):900-4.
1992: A F Nichols; W J Schmidt; Stephen G Chaney; Aziz Sancar
Limitations of the in vitro repair synthesis assay for probing the role of DNA repair in platinum resistance.
Chemico-biological interactions 1992;81(3):223-31.
1992: D K Orren; Christopher P Selby; J E Hearst; Aziz Sancar
Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I.
The Journal of biological chemistry 1992;267(2):780-8.
1991: Christopher P Selby; E M Witkin; Aziz Sancar
Escherichia coli mfd mutant deficient in "mutation frequency decline" lacks strand-specific repair: in vitro complementation with purified coupling factor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11574-8.
1991: ST Kim; P F Heelis; T Okamura; Y Hirata; N Mataga; Aziz Sancar
Determination of rates and yields of interchromophore (folate----flavin) energy transfer and intermolecular (flavin----DNA) electron transfer in Escherichia coli photolyase by time-resolved fluorescence and absorption spectroscopy.
Biochemistry 1991;30(47):11262-70.
1991: Y F Li; Aziz Sancar
Cloning, sequencing, expression and characterization of DNA photolyase from Salmonella typhimurium.
Nucleic acids research 1991;19(18):4885-90.
1991: Christopher P Selby; Aziz Sancar
Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(18):8232-6.
1991: Joyce T Reardon; P Spielmann; J C Huang; S Sastry; Aziz Sancar; J E Hearst
Removal of psoralen monoadducts and crosslinks by human cell free extracts.
Nucleic acids research 1991;19(17):4623-9.
1991: ST Kim; Aziz Sancar
Effect of base, pentose, and phosphodiester backbone structures on binding and repair of pyrimidine dimers by Escherichia coli DNA photolyase.
Biochemistry 1991;30(35):8623-30.
1991: J J Lin; Aziz Sancar
The C-terminal half of UvrC protein is sufficient to reconstitute (A)BC excinuclease.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6824-8.
1991: Y F Li; P F Heelis; Aziz Sancar
Active site of DNA photolyase: tryptophan-306 is the intrinsic hydrogen atom donor essential for flavin radical photoreduction and DNA repair in vitro.
Biochemistry 1991;30(25):6322-9.
1991: E Bertrand-Burggraf; Christopher P Selby; J E Hearst; Aziz Sancar
Identification of the different intermediates in the interaction of (A)BC excinuclease with its substrates by DNase I footprinting on two uniquely modified oligonucleotides.
Journal of molecular biology 1991;219(1):27-36.
1991: G M Myles; Aziz Sancar
Isolation and characterization of functional domains of UvrA.
Biochemistry 1991;30(16):3834-40.
1991: G M Myles; J E Hearst; Aziz Sancar
Site-specific mutagenesis of conserved residues within Walker A and B sequences of Escherichia coli UvrA protein.
Biochemistry 1991;30(16):3824-34.
1991: Christopher P Selby; Aziz Sancar
Noncovalent drug-DNA binding interactions that inhibit and stimulate (A)BC excinuclease.
Biochemistry 1991;30(16):3841-9.
1991: J C Jones; W P Zhen; Eddie Reed; R J Parker; Aziz Sancar; Vilhelm A Bohr
Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells.
The Journal of biological chemistry 1991;266(11):7101-7.
1991: S Cheng; Aziz Sancar; J E Hearst
RecA-dependent incision of psoralen-crosslinked DNA by (A)BC excinuclease.
Nucleic acids research 1991;19(3):657-63.
1990: Christopher P Selby; Aziz Sancar
Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro.
The Journal of biological chemistry 1990;265(34):21330-6.
1990: J J Lin; Aziz Sancar
Reconstitution of nucleotide excision nuclease with UvrA and UvrB proteins from Escherichia coli and UvrC protein from Bacillus subtilis.
The Journal of biological chemistry 1990;265(34):21337-41.
1990: S Hamm-Alvarez; Aziz Sancar; KV Rajagopalan
The folate cofactor of Escherichia coli DNA photolyase acts catalytically.
The Journal of biological chemistry 1990;265(30):18656-62.
1990: D K Orren; Aziz Sancar
Formation and enzymatic properties of the UvrB.DNA complex.
The Journal of biological chemistry 1990;265(26):15796-803.
1990: Aziz Sancar; J E Hearst
The repair patch of E. coli (A)BC excinuclease.
Nucleic acids research 1990;18(17):5051-3.
1990: C P Selby; Aziz Sancar
Structure and function of the (A)BC excinuclease of Escherichia coli.
Mutation research 1990;236(2-3):203-11.
1990: G Payne; Aziz Sancar
Absolute action spectrum of E-FADH2 and E-FADH2-MTHF forms of Escherichia coli DNA photolyase.
Biochemistry 1990;29(33):7715-27.
1990: Aziz Sancar
Substrate overlap and functional competition between human nucleotide excision repair and Escherichia coli photolyase and (a)BC excision nuclease.
Biochemistry 1990;29(24):5711-8.
1990: G Payne; M Wills; C Walsh; Aziz Sancar
Reconstitution of Escherichia coli photolyase with flavins and flavin analogues.
Biochemistry 1990;29(24):5706-11.
1990: Y F Li; Aziz Sancar
Active site of Escherichia coli DNA photolyase: mutations at Trp277 alter the selectivity of the enzyme without affecting the quantum yield of photorepair.
Biochemistry 1990;29(24):5698-706.
1990: P F Heelis; T Okamura; Aziz Sancar
Excited-state properties of Escherichia coli DNA photolyase in the picosecond to millisecond time scale.
Biochemistry 1990;29(24):5694-8.
1990: S F Hamm-Alvarez; Aziz Sancar; KV Rajagopalan
The presence and distribution of reduced folates in Escherichia coli dihydrofolate reductase mutants.
The Journal of biological chemistry 1990;265(17):9850-6.
1990: Christopher P Selby; Aziz Sancar
Molecular mechanisms of DNA repair inhibition by caffeine.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(9):3522-5.
1990: J D Page; I Husain; Aziz Sancar; Stephen G Chaney
Effect of the diaminocyclohexane carrier ligand on platinum adduct formation, repair, and lethality.
Biochemistry 1990;29(4):1016-24.
1990: Christopher P Selby; Aziz Sancar
Mechanisms of caffeine inhibition of DNA repair in E. coli.
Progress in clinical and biological research 1990;340A():179-93.
1989: N S Payne; Aziz Sancar
The LexA protein does not bind specifically to the two SOS box-like sequences immediately 5' to the phr gene.
Mutation research 1989;218(3):207-10.
1989: D C Thomas; D S Okumoto; Aziz Sancar; Vilhelm A Bohr
Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells.
The Journal of biological chemistry 1989;264(30):18005-10.
1989: J J Lin; Aziz Sancar
A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycols from DNA.
Biochemistry 1989;28(20):7979-84.
1989: S Navaratnam; G M Myles; R W Strange; Aziz Sancar
Evidence from extended X-ray absorption fine structure and site-specific mutagenesis for zinc fingers in UvrA protein of Escherichia coli.
The Journal of biological chemistry 1989;264(27):16067-71.
1989: A Kiener; I Husain; Aziz Sancar; C Walsh
Purification and properties of Methanobacterium thermoautotrophicum DNA photolyase.
The Journal of biological chemistry 1989;264(23):13880-7.
1989: D K Orren; Aziz Sancar
The (A)BC excinuclease of Escherichia coli has only the UvrB and UvrC subunits in the incision complex.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5237-41.
1989: G M Myles; Aziz Sancar
DNA repair.
Chemical research in toxicology 1989;2(4):197-226.
1989: I Husain; W Carlton; Aziz Sancar
Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract.
Nucleic acids research 1989;17(12):4471-84.
1989: S Hamm-Alvarez; Aziz Sancar; KV Rajagopalan
Role of enzyme-bound 5,10-methenyltetrahydropteroylpolyglutamate in catalysis by Escherichia coli DNA photolyase.
The Journal of biological chemistry 1989;264(16):9649-56.
1989: JM Voigt; B Van Houten; Aziz Sancar; Michael D Topal
Repair of O6-methylguanine by ABC excinuclease of Escherichia coli in vitro.
The Journal of biological chemistry 1989;264(9):5172-6.
1988: B Van Houten; H Gamper; J E Hearst; Aziz Sancar
Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adducts.
The Journal of biological chemistry 1988;263(32):16553-60.
1988: S Cheng; B Van Houten; H B Gamper; Aziz Sancar; J E Hearst
Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease.
The Journal of biological chemistry 1988;263(29):15110-7.
1988: Christopher P Selby; Aziz Sancar
ABC excinuclease incises both 5' and 3' to the CC-1065-DNA adduct and its incision activity is stimulated by DNA helicase II and DNA polymerase I.
Biochemistry 1988;27(19):7184-8.
1988: I Husain; W L Carrier; J D Regan; Aziz Sancar
Photoreactivation of killing in E. coli K-12 phr- cells is not caused by pyrimidine dimer reversal.
Photochemistry and photobiology 1988;48(2):233-4.
1988: D C Thomas; A G Morton; V A Bohr; Aziz Sancar
General method for quantifying base adducts in specific mammalian genes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):3723-7.
1988: I Husain; Jack D Griffith; Aziz Sancar
Thymine dimers bend DNA.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2558-62.
1988: J L Johnson; S Hamm-Alvarez; G Payne; G B Sancar; KV Rajagopalan; Aziz Sancar
Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2046-50.
1988: Aziz Sancar; G B Sancar
DNA repair enzymes.
Annual review of biochemistry 1988;57():29-67.
1987: G Payne; P F Heelis; B R Rohrs; Aziz Sancar
The active form of Escherichia coli DNA photolyase contains a fully reduced flavin and not a flavin radical, both in vivo and in vitro.
Biochemistry 1987;26(22):7121-7.
1987: I Husain; G B Sancar; S R Holbrook; Aziz Sancar
Mechanism of damage recognition by Escherichia coli DNA photolyase.
The Journal of biological chemistry 1987;262(27):13188-97.
1987: B Van Houten; H Gamper; Aziz Sancar; J E Hearst
DNase I footprint of ABC excinuclease.
The Journal of biological chemistry 1987;262(27):13180-7.
1987: P F Heelis; G Payne; Aziz Sancar
Photochemical properties of Escherichia coli DNA photolyase: selective photodecomposition of the second chromophore.
Biochemistry 1987;26(15):4634-40.
1987: I Husain; Aziz Sancar
Photoreactivation in phr mutants of Escherichia coli K-12.
Journal of bacteriology 1987;169(6):2367-72.
1987: G M Myles; B Van Houten; Aziz Sancar
Utilization of DNA photolyase, pyrimidine dimer endonucleases, and alkali hydrolysis in the analysis of aberrant ABC excinuclease incisions adjacent to UV-induced DNA photoproducts.
Nucleic acids research 1987;15(3):1227-43.
1987: I Husain; Aziz Sancar
Binding of E. coli DNA photolyase to a defined substrate containing a single T mean value of T dimer.
Nucleic acids research 1987;15(3):1109-20.
1987: B Van Houten; Aziz Sancar
Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease.
Journal of bacteriology 1987;169(2):540-5.
1987: G B Sancar; M S Jorns; G Payne; D J Fluke; C S Rupert; Aziz Sancar
Action mechanism of Escherichia coli DNA photolyase. III. Photolysis of the enzyme-substrate complex and the absolute action spectrum.
The Journal of biological chemistry 1987;262(1):492-8.
1987: M S Jorns; Eric Baldwin; G B Sancar; Aziz Sancar
Action mechanism of Escherichia coli DNA photolyase. II. Role of the chromophores in catalysis.
The Journal of biological chemistry 1987;262(1):486-91.
1987: G B Sancar; F W Smith; R Reid; G Payne; M Levy; Aziz Sancar
Action mechanism of Escherichia coli DNA photolyase. I. Formation of the enzyme-substrate complex.
The Journal of biological chemistry 1987;262(1):478-85.
1986: P F Heelis; Aziz Sancar
Photochemical properties of Escherichia coli DNA photolyase: a flash photolysis study.
Biochemistry 1986;25(25):8163-6.
1986: D C Thomas; T A Kunkel; N J Casna; J P Ford; Aziz Sancar
Activities and incision patterns of ABC excinuclease on modified DNA containing single-base mismatches and extrahelical bases.
The Journal of biological chemistry 1986;261(31):14496-505.
1986: B Van Houten; H Gamper; S R Holbrook; J E Hearst; Aziz Sancar
Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(21):8077-81.
1986: B Van Houten; H Gamper; J E Hearst; Aziz Sancar
Construction of DNA substrates modified with psoralen at a unique site and study of the action mechanism of ABC excinuclease on these uniformly modified substrates.
The Journal of biological chemistry 1986;261(30):14135-41.
1986: R F Doolittle; M S Johnson; I Husain; B Van Houten; D C Thomas; Aziz Sancar
Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins.
Nature 1986;323(6087):451-3.
1986: S K Mauldin; F A Richard; M Plescia; SD Wyrick; Aziz Sancar; Stephen G Chaney
High-performance liquid chromatographic separation of platinum complexes containing the cis-1,2-diaminocyclohexane carrier ligand.
Analytical biochemistry 1986;157(1):129-43.
1986: S K Mauldin; I Husain; Aziz Sancar; Stephen G Chaney
Effects of the bidentate malonate ligand on the utilization and cytotoxicity of platinum compounds in the L1210 cell line.
Cancer research 1986;46(6):2876-82.
1986: I Husain; B Van Houten; D C Thomas; Aziz Sancar
Sequences of Escherichia coli uvrA gene and protein reveal two potential ATP binding sites.
The Journal of biological chemistry 1986;261(11):4895-901.
1986: E Arikan; M S Kulkarni; D C Thomas; Aziz Sancar
Sequences of the E. coli uvrB gene and protein.
Nucleic acids research 1986;14(6):2637-50.
1985: D J Beck; S Popoff; Aziz Sancar; W D Rupp
Reactions of the UVRABC excision nuclease with DNA damaged by diamminedichloroplatinum(II).
Nucleic acids research 1985;13(20):7395-412.
1985: I Husain; B Van Houten; D C Thomas; M Abdel-Monem; Aziz Sancar
Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(20):6774-8.
1985: D E Brash; W A Franklin; G B Sancar; Aziz Sancar; W A Haseltine
Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts.
The Journal of biological chemistry 1985;260(21):11438-41.
1985: I Husain; Stephen G Chaney; Aziz Sancar
Repair of cis-platinum-DNA adducts by ABC excinuclease in vivo and in vitro.
Journal of bacteriology 1985;163(3):817-23.
1985: Aziz Sancar; K A Franklin; G Sancar; M S Tang
Repair of psoralen and acetylaminofluorene DNA adducts by ABC excinuclease.
Journal of molecular biology 1985;184(4):725-34.
1985: D C Thomas; M Levy; Aziz Sancar
Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli.
The Journal of biological chemistry 1985;260(17):9875-83.
1985: M S Jorns; G B Sancar; Aziz Sancar
Identification of oligothymidylates as new simple substrates for Escherichia coli DNA photolyase and their use in a rapid spectrophotometric enzyme assay.
Biochemistry 1985;24(8):1856-61.
1985: G B Sancar; F W Smith; Aziz Sancar
Binding of Escherichia coli DNA photolyase to UV-irradiated DNA.
Biochemistry 1985;24(8):1849-55.
1984: Aziz Sancar; K A Franklin; G B Sancar
Escherichia coli DNA photolyase stimulates uvrABC excision nuclease in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7397-401.
1984: B E Markham; J E Harper; D W Mount; G B Sancar; Aziz Sancar; W D Rupp; Cynthia Kenyon; Graham C Walker
Analysis of mRNA synthesis following induction of the Escherichia coli SOS system.
Journal of molecular biology 1984;178(2):237-48.
1984: G B Sancar; Aziz Sancar; W D Rupp
Sequences of the E. coli uvrC gene and protein.
Nucleic acids research 1984;12(11):4593-608.
1984: M S Jorns; G B Sancar; Aziz Sancar
Identification of a neutral flavin radical and characterization of a second chromophore in Escherichia coli DNA photolyase.
Biochemistry 1984;23(12):2673-9.
1984: G B Sancar; F W Smith; M C Lorence; C S Rupert; Aziz Sancar
Sequences of the Escherichia coli photolyase gene and protein.
The Journal of biological chemistry 1984;259(9):6033-8.
1984: Aziz Sancar; F W Smith; G B Sancar
Purification of Escherichia coli DNA photolyase.
The Journal of biological chemistry 1984;259(9):6028-32.
1984: Aziz Sancar; G B Sancar
Escherichia coli DNA photolyase is a flavoprotein.
Journal of molecular biology 1984;172(2):223-7.
1983: G B Sancar; F W Smith; Aziz Sancar
Identification and amplification of the E. coli phr gene product.
Nucleic acids research 1983;11(19):6667-78.
1983: Roger A Schultz; E C Friedberg; Robb Moses; W D Rupp; Aziz Sancar; S Sharma
Use of an Escherichia coli mutant strain permits measurement of single-stranded apurinic-apyrimidinic endonuclease in crude extracts: studies with untransformed cells and cells transformed with plasmids containing the uvrC gene.
Journal of bacteriology 1983;154(3):1459-61.
1983: Aziz Sancar; W D Rupp
A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region.
Cell 1983;33(1):249-60.
1982: W D Rupp; Aziz Sancar; G B Sancar
Properties and regulation of the UVRABC endonuclease.
Biochimie 1982;64(8-9):595-8.
1982: Aziz Sancar; G B Sancar; W D Rupp; J W Little; D W Mount
LexA protein inhibits transcription of the E. coli uvrA gene in vitro.
Nature 1982;298(5869):96-8.
1982: G B Sancar; Aziz Sancar; J W Little; W D Rupp
The uvrB gene of Escherichia coli has both lexA-repressed and lexA-independent promoters.
Cell 1982;28(3):523-30.
1982: B E Uhlin; M R Volkert; A J Clark; Aziz Sancar; W D Rupp
Nucleotide sequence of a recA operator mutation. LexA/operator-repressor binding/inducible repair.
Molecular & general genetics : MGG 1982;185(2):251-4.
1981: B M Kacinski; Aziz Sancar; W D Rupp
A general approach for purifying proteins encoded by cloned genes without using a functional assay: isolation of the uvrA gene product from radiolabeled maxicells.
Nucleic acids research 1981;9(18):4495-508.
1981: Aziz Sancar; B M Kacinski; D L Mott; W D Rupp
Identification of the uvrC gene product.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(9):5450-4.
1981: Aziz Sancar; K R Williams; J W Chase; W D Rupp
Sequences of the ssb gene and protein.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4274-8.
1981: Aziz Sancar; N D Clarke; J Griswold; W J Kennedy; W D Rupp
Identification of the uvrB gene product.
Journal of molecular biology 1981;148(1):63-76.
1981: Aziz Sancar; R P Wharton; S Seltzer; B M Kacinski; N D Clarke; W D Rupp
Identification of the uvrA gene product.
Journal of molecular biology 1981;148(1):45-62.
1980: J W Chase; R F Whittier; J Auerbach; Aziz Sancar; W D Rupp
Amplification of single-strand DNA binding protein in Escherichia coli.
Nucleic acids research 1980;8(14):3215-27.
1980: Aziz Sancar; C Stachelek; W Konigsberg; W D Rupp
Sequences of the recA gene and protein.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(5):2611-5.
1979: Aziz Sancar; W D Rupp
Cloning of uvrA, lexC and ssb genes of Escherichia coli.
Biochemical and biophysical research communications 1979;90(1):123-9.
1979: Aziz Sancar; W D Rupp
Physical map of the recA gene.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(7):3144-8.
1979: Aziz Sancar; C S Rupert
Penicillin selection of Escherichia coli deoxyribonucleic acid repair mutants.
Journal of bacteriology 1979;138(3):779-82.
1979: Aziz Sancar; A M Hack; W D Rupp
Simple method for identification of plasmid-coded proteins.
Journal of bacteriology 1979;137(1):692-3.
1978: Aziz Sancar; C S Rupert
Cloning of the phr gene and amplification of photolyase in Escherichia coli.
Gene 1978;4(4):295-308.
1978: Aziz Sancar; C S Rupert
Determination of plasmid molecular weights from ultraviolet sensitivities.
Nature 1978;272(5652):471-2.