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John Sanders

Research Profile

Chemicals & Drugs

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X Ray Crystallography

Physiology

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Mouse

Anatomy

Metatarsal Bones

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Publications

TOP 3
Junhong Mao; Sujoy Mukherjee; Yong Zhang; Rong Cao; John M Sanders; Yongcheng Song; Yonghui Zhang; Gary A Meints; Yi-Gui Gao; Dushyant Mukkamala; Michael P Hudock; Eric Oldfield
Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.
John M Sanders; Yongcheng Song; Julian M W Chan; Yonghui Zhang; Samuel Jennings; Thomas Kosztowski; Sarah Odeh; Ryan Flessner; Christine Schwerdtfeger; Evangelia Kotsikorou; Gary A Meints; Aurora Ortiz Gómez; Dolores González-Pacanowska; Amy M Raker; Hong Wang; Ermond R Van Beek; Socrates E Papapoulos; Craig Morita; Eric Oldfield
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption.
Yongcheng Song; Yonghui Zhang; Hong Wang; Amy M Raker; John M Sanders; Erin Broderick; Allen Clark; Craig Morita; Eric Oldfield
Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation.

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All Publications

2006: Junhong Mao; Sujoy Mukherjee; Yong Zhang; Rong Cao; John M Sanders; Yongcheng Song; Yonghui Zhang; Gary A Meints; Yi-Gui Gao; Dushyant Mukkamala; Michael P Hudock; Eric Oldfield
Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.
Journal of the American Chemical Society 2006;128(45):14485-97.
2005: John M Sanders; Yongcheng Song; Julian M W Chan; Yonghui Zhang; Samuel Jennings; Thomas Kosztowski; Sarah Odeh; Ryan Flessner; Christine Schwerdtfeger; Evangelia Kotsikorou; Gary A Meints; Aurora Ortiz Gómez; Dolores González-Pacanowska; Amy M Raker; Hong Wang; Ermond R Van Beek; Socrates E Papapoulos; Craig Morita; Eric Oldfield
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption.
Journal of medicinal chemistry 2005;48(8):2957-63.
2004: Yongcheng Song; Yonghui Zhang; Hong Wang; Amy M Raker; John M Sanders; Erin Broderick; Allen Clark; Craig Morita; Eric Oldfield
Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation.
Bioorganic & medicinal chemistry letters 2004;14(17):4471-7.
2004: John M Sanders; Subhash Ghosh; Julian M W Chan; Gary A Meints; Hong Wang; Amy M Raker; Yongcheng Song; Alison Colantino; Agnieszka Burzynska; Pawel Kafarski; Craig Morita; Eric Oldfield
Quantitative structure-activity relationships for gammadelta T cell activation by bisphosphonates.
Journal of medicinal chemistry 2004;47(2):375-84.
2003: John M Sanders; Aurora Ortiz Gómez; Junhong Mao; Gary A Meints; Erin M Van Brussel; Agnieszka Burzynska; Pawel Kafarski; Dolores González-Pacanowska; Eric Oldfield
3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates.
Journal of medicinal chemistry 2003;46(24):5171-83.
2003: Andrea Montalvetti; Alexis Fernandez; John M Sanders; Subhash Ghosh; Erin M Van Brussel; Eric Oldfield; Roberto Docampo
Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma brucei. In vitro RNA interference and in vivo inhibition studies.
The Journal of biological chemistry 2003;278(19):17075-83.
2002: Michael B Martin; John M Sanders; Howard Kendrick; Kate de Luca-Fradley; Jared C Lewis; Joshua S Grimley; Erin M Van Brussel; Jeffrey R Olsen; Gary A Meints; Agnieszka Burzynska; Pawel Kafarski; Simon L Croft; Eric Oldfield
Activity of bisphosphonates against Trypanosoma brucei rhodesiense.
Journal of medicinal chemistry 2002;45(14):2904-14.
2002: Christina M Szabo; Yoshihiro Matsumura; Sayaka Fukura; Michael B Martin; John M Sanders; Suraj Sengupta; John A Cieslak; Timothy C Loftus; Christopher R Lea; Hyung-Jae Lee; Ali Koohang; Robert M Coates; Hiroshi Sagami; Eric Oldfield
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents.
Journal of medicinal chemistry 2002;45(11):2185-96.