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Philippe Sansonetti

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Cindy Fevre; Michel Huerre; AURELIE KIEUSSEIAN; Thierry Pedron; Marie-Christine Prevost; Philippe J Sansonetti; Solenne Taront; Ana S Almeida; Sylvain Brisse; Ana Cumano; Régis Tournebize
A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
Wilmara Salgado-Pabón; Philippe J Sansonetti; Gernot Sellge; Pascal Roux; Ellen T Arena; Philippe Bousso; Susanna Celli; Elisabetta Frigimelica; Katharina Nothelfer; Armelle Phalipon
Shigella impairs T lymphocyte dynamics in vivo.
Takahiro Matsuki; Céline Mulet; Thierry Pédron; Béatrice Regnault; Taeko Hara; Philippe J Sansonetti
Epithelial Cell Proliferation Arrest Induced by Lactate and Acetate from Lactobacillus casei and Bifidobacterium breve.

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All Publications

2013: Cindy Fevre; Michel Huerre; AURELIE KIEUSSEIAN; Thierry Pedron; Marie-Christine Prevost; Philippe J Sansonetti; Solenne Taront; Ana S Almeida; Sylvain Brisse; Ana Cumano; Régis Tournebize
A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
EMBO molecular medicine 2013;5(4):516-30.
2013: Wilmara Salgado-Pabón; Philippe J Sansonetti; Gernot Sellge; Pascal Roux; Ellen T Arena; Philippe Bousso; Susanna Celli; Elisabetta Frigimelica; Katharina Nothelfer; Armelle Phalipon
Shigella impairs T lymphocyte dynamics in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):4458-63.
2013: Takahiro Matsuki; Céline Mulet; Thierry Pédron; Béatrice Regnault; Taeko Hara; Philippe J Sansonetti
Epithelial Cell Proliferation Arrest Induced by Lactate and Acetate from Lactobacillus casei and Bifidobacterium breve.
PloS one 2013;8(4):e63053.
2013: Paul Erlich; Philippe J Sansonetti
[Acute intestinal infections: current and upcoming vaccines].
Presse médicale (Paris, France : 1983) 2013;42(1):93-101.
2012: Joëlle Mounier; Jean-Christophe Olivo-Marin; Franck Perez; Philippe J Sansonetti; Gaëlle Boncompain; Fabrice Chrétien; Michael Kolbe; Thibault Lagache; Lidija Senerovic; Nathalie Sauvonnet
Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion.
Cell host & microbe 2012;12(3):381-9.
2012: Helge Karch; Eliora Z Ron; Philippe J Sansonetti; Tone Tønjum; Erick Denamur; Ulrich Dobrindt; B Brett Finlay; Regine Hengge; Ludgers Johannes; Miguel Vicente
The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak.
EMBO molecular medicine 2012;4(9):841-8.
2012: Ian Teo; Steve M Toms; Mire Zloh; Peter Simpson; Chris Tang; Teresa S Barata; Tracey Bell; Karen A Johnston; Benoit Marteyn; Steve Matthews; Andrea Puhar; Phillip M Rendle; Philippe J Sansonetti; Pamela Schnupf; Sunil Shaunak
Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers.
EMBO molecular medicine 2012;4(9):866-81.
2012: Yves-Marie Coïc; Elisabeth Labruyere; Thierry Lazure; Laurence Mulard; Philippe J Sansonetti; Gunter Schneider; Iradj Sobhani; Roman Thibeaux; Benjamin Wyplosz; Ömer Poyraz; Francoise Baleux; Fabrice Chretien; Benoit S Marteyn
Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain.
The Journal of biological chemistry 2012;287(19):15916-22.
2012: Pamela Schnupf; Philippe J Sansonetti
Quantitative RT-PCR profiling of the rabbit immune response: assessment of acute Shigella flexneri infection.
PloS one 2012;7(6):e36446.
2012: Thierry Pédron; Christian Chervaux; Catherine Dauga; Lionel Frangeul; Gianfranco Grompone; Céline Mulet; Philippe J Sansonetti
A crypt-specific core microbiota resides in the mouse colon.
mBio 2012;3(3):.
2012: Clotilde Bongrand; Philippe J Sansonetti; Claude Parsot
Characterization of the promoter, MxiE box and 5' UTR of genes controlled by the activity of the type III secretion apparatus in Shigella flexneri.
PloS one 2012;7(3):e32862.
2011: Damien Ramel; Philippe J Sansonetti; Hélène Tronchère; Véronique Pons; Gaëtan Chicanne; Sophie Dupuis-Coronas; Frédérique Gaits-Iacovoni; Frédéric Lagarrigue; Joëlle Mounier; Bernard Payrastre
Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling.
Science signaling 2011;4(191):ra61.
2011: Jacques Amar; Mathieu Bergé; Luis G Bermúdez-Humarán; Chantal Chabo; Pascale Klopp; Sampo Lahtinen; Philippe Langella; Arthur Ouwehand; Nina Rautonen; Philippe J Sansonetti; Natalia Smirnova; Thierry Sulpice; Christelle Vachoux; Aurélie Waget; Rémy Burcelin
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.
EMBO molecular medicine 2011;3(9):559-72.
2011: Stéphane Romero; Philippe J Sansonetti; Nathalie Carayol; Gianfranco Grompone; Stéphanie Guadagnini; Joëlle Mounier; Marie-Christine Prevost; Guy Tran Van Nhieu
ATP-mediated Erk1/2 activation stimulates bacterial capture by filopodia, which precedes Shigella invasion of epithelial cells.
Cell host & microbe 2011;9(6):508-19.
2011: Stephanie P Jehl; Amy M Doling; Kara S Giddings; Armelle Phalipon; Philippe J Sansonetti; Marcia B Goldberg; Michael N Starnbach
Antigen-specific CD8(+) T cells fail to respond to Shigella flexneri.
Infection and immunity 2011;79(5):2021-30.
2011: Christoph Konradt; Elisabetta Frigimelica; Katharina Nothelfer; Andrea Puhar; Wilmara Salgado-Pabon; Vincenzo Di Bartolo; Daniel Scott-Algara; Cristina D Rodrigues; Philippe J Sansonetti; Armelle Phalipon
The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism.
Cell host & microbe 2011;9(4):263-72.
2011: Mathurin Flamant; Philippe Aubert; Malvyne Rolli-Derkinderen; Arnaud Bourreille; Margarida Ribeiro Neunlist; Maxime M Mahé; Guillaume Meurette; Benoit Marteyn; Tor Savidge; Jean Paul Galmiche; Philippe J Sansonetti; michel neunlist
Enteric glia protect against Shigella flexneri invasion in intestinal epithelial cells: a role for S-nitrosoglutathione.
Gut 2011;60(4):473-84.
2011: Thomas A Kufer; Philippe J Sansonetti
NLR functions beyond pathogen recognition.
Nature immunology 2011;12(2):121-8.
2011: Benoit Marteyn; Francesco Berlanda Scorza; Philippe J Sansonetti; Christoph Tang
Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract.
Cellular microbiology 2011;13(2):171-6.
2011: Kazi Mizanur Rahman; Shams El Arifeen; K Zaman; Mahbubur Rahman; Rubhana Raqib; Muhammad B. Yunus; Nazma Begum; Md Shaheenul Islam; Badrul Munir Sohel; Mahbubur Rahman; Malabi M Venkatesan; Thomas L Hale; Daniel W Isenbarger; Philippe J Sansonetti; Robert E Black; Abdullah Baqui
Safety, dose, immunogenicity, and transmissibility of an oral live attenuated Shigella flexneri 2a vaccine candidate (SC602) among healthy adults and school children in Matlab, Bangladesh.
Vaccine 2011;29(6):1347-54.
2011: Philippe J Sansonetti
To be or not to be a pathogen: that is the mucosally relevant question.
Mucosal immunology 2011;4(1):8-14.
2010: Adolfo García-Sastre; Philippe J Sansonetti
Host-pathogen interactions.
Current opinion in immunology 2010;22(4):425-7.
2010: Sébastien Dharancy; Mathilde Body-Malapel; Alexandre Louvet; Dominique Berrebi; Emilie Gantier; Philippe Gosset; Jérôme Viala; Antoine Hollebecque; Christophe Moreno; Dana J Philpott; Stephen E Girardin; Philippe J Sansonetti; Pierre Desreumaux; Philippe Mathurin; Laurent Dubuquoy
Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control.
Gastroenterology 2010;138(4):1546-56, 1556.e1-5.
2009: Nicolas Dupont; Sandra Lacas-Gervais; Julie Bertout; Irit Paz; Barbara Freche; Guy Tran Van Nhieu; F Gisou van der Goot; Philippe J Sansonetti; Frank Lafont
Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy.
Cell host & microbe 2009;6(2):137-49.
2009: Philippe J Sansonetti; Ruslan Medzhitov
Learning tolerance while fighting ignorance.
Cell 2009;138(3):416-20.
2009: Philippe J Sansonetti
Framing a concept and an agenda for infectious diseases in EMBO Molecular Medicine.
EMBO molecular medicine 2009;1(4):193-4.
2009: Katrina Ray; Benoit Marteyn; Philippe J Sansonetti; Christoph M Tang
Life on the inside: the intracellular lifestyle of cytosolic bacteria.
Nature reviews. Microbiology 2009;7(5):333-40.
2009: Leticia A M Carneiro; Leonardo H Travassos; Fraser Soares; Ivan Tattoli; Joao G Magalhaes; Marcelo T Bozza; Maria C Plotkowski; Philippe J Sansonetti; Jeffery D Molkentin; Dana J Philpott; Stephen E Girardin
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.
Cell host & microbe 2009;5(2):123-36.
2009: Armelle Phalipon; Myriam Tanguy; Cyrille Grandjean; Catherine Guerreiro; Frédéric Bélot; Dani Cohen; Philippe J Sansonetti; Laurence A Mulard
A synthetic carbohydrate-protein conjugate vaccine candidate against Shigella flexneri 2a infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2241-7.
2009: Emmanuel Coron; Mathurin Flamant; Philippe Aubert; Thilo Wedel; Thierry Pedron; Eric Letessier; Jean P Galmiche; Philippe J Sansonetti; michel neunlist
Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon.
PloS one 2009;4(3):e4713.
2009: Joëlle Mounier; Michel R Popoff; Jost Enninga; Margaret C Frame; Philippe J Sansonetti; Guy Tran Van Nhieu
The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells.
PLoS pathogens 2009;5(1):e1000271.
2008: Alexander U Singer; John R Rohde; Robert Lam; Tatiana Skarina; Olga Kagan; Rosa Dileo; Nickolay Y Chirgadze; Marianne E Cuff; Andrzej Joachimiak; Mike Tyers; Philippe J Sansonetti; Claude Parsot; Alexei Savchenko
Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.
Nature structural & molecular biology 2008;15(12):1293-301.
2008: Armelle Phalipon; Laurence A Mulard; Philippe J Sansonetti
Vaccination against shigellosis: is it the path that is difficult or is it the difficult that is the path?
Microbes and infection / Institut Pasteur 2008;10(9):1057-62.
2008: Philippe J Sansonetti
Host-bacteria homeostasis in the healthy and inflamed gut.
Current opinion in gastroenterology 2008;24(4):435-9.
2008: Brice Sperandio; Béatrice Regnault; Jianhua Guo; Zhi Zhang; Samuel L Stanley; Philippe J Sansonetti; Thierry Pédron
Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression.
The Journal of experimental medicine 2008;205(5):1121-32.
2008: Philippe J Sansonetti
War and peace at the intestinal epithelial surface: an integrated view of bacterial commensalism versus bacterial pathogenicity.
Journal of pediatric gastroenterology and nutrition 2008;46 Suppl 1():E6-7.
2008: M Isabel Fernandez; Béatrice Regnault; Céline Mulet; Myriam Tanguy; Philippe Jay; Philippe J Sansonetti; Thierry Pédron
Maturation of paneth cells induces the refractory state of newborn mice to Shigella infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4924-30.
2008: Mathilde Body-Malapel; Sébastien Dharancy; Dominique Berrebi; Alexandre Louvet; Jean-Pierre Hugot; Dana J Philpott; Marco Giovannini; Fabrice Chareyre; Gilles Pages; Emilie Gantier; Stephen E Girardin; IRENE GARCIA; Sylvie Hudault; Filoména Conti; Philippe J Sansonetti; Mathias Chamaillard; Pierre Desreumaux; Laurent Dubuquoy; Philippe Mathurin
NOD2: a potential target for regulating liver injury.
Laboratory investigation; a journal of technical methods and pathology 2008;88(3):318-27.
2008: Christine Sadorge; Anna Ndiaye; Nathalie Beveridge; Schale Frazer; Rafaela Giemza; Nathalie Jolly; Julie Johnson; Helen Liddy; Catherine Cosgrove; Paola Allavena; Alberto Mantovani; Stéphane Béchet; Annick Fontaine-Thompson; George E Griffin; Francis Dupont; Philippe J Sansonetti; David J M Lewis
Phase 1 clinical trial of live attenuated Shigella dysenteriae type-1 DeltaicsA Deltaent Deltafep DeltastxA:HgR oral vaccine SC599 in healthy human adult volunteers.
Vaccine 2008;26(7):978-87.
2008: Thomas Kufer; Elisabeth Kremmer; Alexander C Adam; Dana J Philpott; Philippe J Sansonetti
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction.
Cellular microbiology 2008;10(2):477-86.
2008: Valentin Jaumouillé; Olivera Francetic; Philippe J Sansonetti; Guy Tran Van Nhieu
Cytoplasmic targeting of IpaC to the bacterial pole directs polar type III secretion in Shigella.
The EMBO journal 2008;27(2):447-57.
2008: Philippe J Sansonetti
Molecular and cellular bases of bacterial virulence: guessing the future episodes of an ongoing saga.
Research in microbiology 2008;159(1):59-61.
2007: Laurence Arbibe; Philippe J Sansonetti
Epigenetic regulation of host response to LPS: causing tolerance while avoiding Toll errancy.
Cell host & microbe 2007;1(4):244-6.
2007: John R Rohde; Ashton Breitkreutz; Alexandre Chenal; Philippe J Sansonetti; Claude Parsot
Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.
Cell host & microbe 2007;1(1):77-83.
2007: Nalini Ramarao; Christophe Le Clainche; Tina Izard; Raphaëlle Bourdet-Sicard; Elisabeth Ageron; Philippe J Sansonetti; Marie-France Carlier; Guy Tran Van Nhieu
Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain.
FEBS letters 2007;581(5):853-7.
2007: Doo-Hee Shim; Toshihiko Suzuki; Sun-Young Chang; Sung-Moo Park; Philippe J Sansonetti; Chihiro Sasakawa; Mi-Na Kweon
New animal model of shigellosis in the Guinea pig: its usefulness for protective efficacy studies.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2476-82.
2007: Philippe J Sansonetti; James P Di Santo
Debugging how bacteria manipulate the immune response.
Immunity 2007;26(2):149-61.
2007: Armelle Phalipon; Philippe J Sansonetti
Shigella's ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival?
Immunology and cell biology 2007;85(2):119-29.
2007: Thomas Kufer; Philippe J Sansonetti
Sensing of bacteria: NOD a lonely job.
Current opinion in microbiology 2007;10(1):62-9.
2007: Laurence Arbibe; Dong Wook Kim; Eric Batsché; Thierry Pedron; Bogdan Mateescu; Christian Muchardt; Claude Parsot; Philippe J Sansonetti
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.
Nature immunology 2007;8(1):47-56.
2006: Philippe J Sansonetti
The innate signaling of dangers and the dangers of innate signaling.
Nature immunology 2006;7(12):1237-42.
2006: Philippe J Sansonetti
Shigellosis: an old disease in new clothes?
PLoS medicine 2006;3(9):e354.
2006: Philippe J Sansonetti
The bacterial weaponry: lessons from Shigella.
Annals of the New York Academy of Sciences 2006;1072():307-12.
2006: Caroline Pendaries; Hélène Tronchère; Laurence Arbibe; Joëlle Mounier; Or Gozani; Lewis Cantley; Michael J Fry; Frédérique Gaits-Iacovoni; Philippe J Sansonetti; Bernard Payrastre
PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.
The EMBO journal 2006;25(5):1024-34.
2006: Philippe J Sansonetti
Rupture, invasion and inflammatory destruction of the intestinal barrier by Shigella: the yin and yang of innate immunity.
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada 2006;17(2):117-9.
2006: Armelle Phalipon; Corina Costachel; Cyrille Grandjean; Audrey Thuizat; Catherine Guerreiro; Myriam Tanguy; Farida Nato; Brigitte Vulliez-Le Normand; Frédéric Bélot; Karen Wright; Véronique Marcel-Peyre; Philippe J Sansonetti; Laurence A Mulard
Characterization of functional oligosaccharide mimics of the Shigella flexneri serotype 2a O-antigen: implications for the development of a chemically defined glycoconjugate vaccine.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1686-94.
2006: Meng-Tsung Tien; Stephen E Girardin; Béatrice Regnault; Lionel Le Bourhis; Marie-Agnès Dillies; Jean-Yves Coppée; Raphaëlle Bourdet-Sicard; Philippe J Sansonetti; Thierry Pédron
Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):1228-37.
2006: Régis Tournebize; Bich-Thuy Doan; Marie-Agnès Dillies; Sabine Maurin; Jean-Claude Beloeil; Philippe J Sansonetti
Magnetic resonance imaging of Klebsiella pneumoniae-induced pneumonia in mice.
Cellular microbiology 2006;8(1):33-43.
2005: Joao Gamelas Magalhaes; Dana J Philpott; Marie-Anne Nahori; Muguette Jéhanno; Joerg Fritz; Lionel Le Bourhis; Jérôme Viala; Jean-Pierre Hugot; Marco Giovannini; John Bertin; Michel Lepoivre; Dominique Mengin-Lecreulx; Philippe J Sansonetti; Stephen E Girardin
Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin.
EMBO reports 2005;6(12):1201-7.
2005: Stephen E Girardin; Muguette Jéhanno; Dominique Mengin-Lecreulx; Philippe J Sansonetti; Pedro Alzari; Dana J Philpott
Identification of the critical residues involved in peptidoglycan detection by Nod1.
The Journal of biological chemistry 2005;280(46):38648-56.
2005: Mihai G Netea; Gerben Ferwerda; Dirk J de Jong; Catherine Werts; Ivo G Boneca; Muguette Jéhanno; Jos W M van der Meer; Dominique Mengin-Lecreulx; Philippe J Sansonetti; Dana J Philpott; Sébastien Dharancy; Stephen E Girardin
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists.
The Journal of biological chemistry 2005;280(43):35859-67.
2005: Dong Wook Kim; Gerlinde Lenzen; Anne-Laure Page; Pierre Legrain; Philippe J Sansonetti; Claude Parsot
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):14046-51.
2005: Karine Le-Barillec; Joao Gamelas Magalhaes; Erwan Corcuff; Audrey Thuizat; Philippe J Sansonetti; Armelle Phalipon; James P Di Santo
Roles for T and NK cells in the innate immune response to Shigella flexneri.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1735-40.
2005: Maria Celeste Martino; Giacomo Rossi; Irene Martini; Ivan Tattoli; Damiana Chiavolini; Armelle Phalipon; Philippe J Sansonetti; Maria Bernardini
Mucosal lymphoid infiltrate dominates colonic pathological changes in murine experimental shigellosis.
The Journal of infectious diseases 2005;192(1):136-48.
2005: Anne-France Petit-Bertron; Thierry Pedron; Ulrich Gross; Jean-Yves Coppée; Philippe J Sansonetti; Jean-Marc Cavaillon; Minou Adib-Conquy
Adherence modifies the regulation of gene expression induced by interleukin-10.
Cytokine 2005;29(1):1-12.
2004: Philippe J Sansonetti
War and peace at mucosal surfaces.
Nature reviews. Immunology 2004;4(12):953-64.
2004: Jérôme Viala; Catherine Chaput; Ivo G Boneca; Ana Cardona; Stephen E Girardin; Anthony P Moran; Rafika Athman; Sylvie Mémet; Michel R Huerre; Anthony J Coyle; Peter S DiStefano; Philippe J Sansonetti; Agnès Labigne; John Bertin; Dana J Philpott; Richard L Ferrero
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island.
Nature immunology 2004;5(11):1166-74.
2004: Monique Singer; Philippe J Sansonetti
IL-8 is a key chemokine regulating neutrophil recruitment in a new mouse model of Shigella-induced colitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):4197-206.
2004: Laurence Bougnères; Stephen E Girardin; Scott A Weed; Andrei Karginov; Jean-Christophe Olivo-Marin; Thomas J Parsons; Philippe J Sansonetti; Guy Tran Van Nhieu
Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells.
The Journal of cell biology 2004;166(2):225-35.
2004: Pascale Cossart; Philippe J Sansonetti
Bacterial invasion: the paradigms of enteroinvasive pathogens.
Science (New York, N.Y.) 2004;304(5668):242-8.
2003: Stephen E Girardin; Jean-Pierre Hugot; Philippe J Sansonetti
Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing.
Trends in immunology 2003;24(12):652-8.
2003: Stephen E Girardin; Leonardo Travassos; Mireille Hervé; Didier Blanot; Ivo G Boneca; Dana J Philpott; Philippe J Sansonetti; Dominique Mengin-Lecreulx
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.
The Journal of biological chemistry 2003;278(43):41702-8.
2003: Thierry Pédron; Christelle Thibault; Philippe J Sansonetti
The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2.
The Journal of biological chemistry 2003;278(36):33878-86.
2003: Nicholas P West; Philippe J Sansonetti; Gad Frankel; Christoph M Tang
Finding your niche: what has been learnt from STM studies on GI colonization.
Trends in microbiology 2003;11(7):338-44.
2003: M Isabel Fernandez; Audrey Thuizat; Thierry Pedron; M Neutra; Armelle Phalipon; Philippe J Sansonetti
A newborn mouse model for the study of intestinal pathogenesis of shigellosis.
Cellular microbiology 2003;5(7):481-91.
2003: Stephen E Girardin; Ivo G Boneca; Leticia Carneiro; Aude Antignac; Muguette Jéhanno; Jérôme Viala; Karsten Tedin; Muhamed-Kheir Taha; Agnès Labigne; Ulrich Zähringer; Anthony J Coyle; Peter S DiStefano; John Bertin; Philippe J Sansonetti; Dana J Philpott
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan.
Science (New York, N.Y.) 2003;300(5625):1584-7.
2003: M Isabel Fernandez; Thierry Pedron; Régis Tournebize; Jean-Christophe Olivo-Marin; Philippe J Sansonetti; Armelle Phalipon
Anti-inflammatory role for intracellular dimeric immunoglobulin a by neutralization of lipopolysaccharide in epithelial cells.
Immunity 2003;18(6):739-49.
2003: M Isabel Fernandez; Philippe J Sansonetti
Shigella interaction with intestinal epithelial cells determines the innate immune response in shigellosis.
International journal of medical microbiology : IJMM 2003;293(1):55-67.
2003: Mathias Chamaillard; Dana J Philpott; Stephen E Girardin; Habib Zouali; Suzanne Lesage; Fabrice Chareyre; The-Hung Bui; Marco Giovannini; Ulrich Zaehringer; Virginie Penard-Lacronique; Philippe J Sansonetti; Jean-Pierre Hugot; Gilles Thomas
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3455-60.
2003: Stephen E Girardin; Ivo G Boneca; Jérôme Viala; Mathias Chamaillard; Agnès Labigne; Gilles Thomas; Dana J Philpott; Philippe J Sansonetti
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection.
The Journal of biological chemistry 2003;278(11):8869-72.
2003: Armelle Phalipon; Philippe J Sansonetti
Shigellosis: innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine development.
Critical reviews in immunology 2003;23(5-6):371-401.
2002: Maria Mavris; Philippe J Sansonetti; Claude Parsot
Identification of the cis-acting site involved in activation of promoters regulated by activity of the type III secretion apparatus in Shigella flexneri.
Journal of bacteriology 2002;184(24):6751-9.
2002: Kirsten Niebuhr; Sylvie Giuriato; Thierry Pedron; Dana J Philpott; Frédérique Gaits; Julia Sable; Michael P Sheetz; Claude Parsot; Philippe J Sansonetti; Bernard Payrastre
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology.
The EMBO journal 2002;21(19):5069-78.
2002: Armelle Phalipon; Ana Cardona; Jean-Pierre Kraehenbuhl; Léna Edelman; Philippe J Sansonetti; Blaise Corthésy
Secretory component: a new role in secretory IgA-mediated immune exclusion in vivo.
Immunity 2002;17(1):107-15.
2002: Lucy J Hathaway; George E Griffin; Philippe J Sansonetti; Jonathan D Edgeworth
Human monocytes kill Shigella flexneri but then die by apoptosis associated with suppression of proinflammatory cytokine production.
Infection and immunity 2002;70(7):3833-42.
2002: Karla Jean Fullner; John C Boucher; Martha A Hanes; G Kenneth Haines; Brian M Meehan; Cynthia Walchle; Philippe J Sansonetti; John J Mekalanos
The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model.
The Journal of experimental medicine 2002;195(11):1455-62.
2002: Rubhana Raqib; Caroline Ekberg; Protim Sharkar; Pradip K Bardhan; Arturo Zychlinsky; Philippe J Sansonetti; Jan Andersson
Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2.
Infection and immunity 2002;70(6):3199-207.
2002: Hélène D'Hauteville; Shahid Khan; duncan maskell; Anders Kussak; Andrej Weintraub; John C Mathison; Richard J Ulevitch; Nicole Wuscher; Claude Parsot; Philippe J Sansonetti
Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5240-51.
2002: Jonathan D Edgeworth; Jo Spencer; Armelle Phalipon; George E Griffin; Philippe J Sansonetti
Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells.
European journal of immunology 2002;32(5):1464-71.
2002: Katharine A Reed; Michael E Hobert; Claire E Kolenda; Kara A Sands; Michelle B. Rathman; Miriam O'Connor; Sean Lyons; Andrew T Gewirtz; Philippe J Sansonetti; James L Madara
The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cells.
The Journal of biological chemistry 2002;277(15):13346-53.
2002: Stephen E Girardin; Philippe J Sansonetti; Dana J Philpott
Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies.
Trends in microbiology 2002;10(4):193-9.
2001: Stephen E Girardin; Régis Tournebize; Maria Mavris; Anne-Laure Page; X Li; G R Stark; John Bertin; Peter S DiStefano; Moshe Yaniv; Philippe J Sansonetti; Dana J Philpott
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.
EMBO reports 2001;2(8):736-42.
2001: Philippe J Sansonetti
Microbes and microbial toxins: paradigms for microbial-mucosal interactions III. Shigellosis: from symptoms to molecular pathogenesis.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(3):G319-23.
2001: Maria Bernardini; J Arondel; Irene Martini; A Aidara; Philippe J Sansonetti
Parameters underlying successful protection with live attenuated mutants in experimental shigellosis.
Infection and immunity 2001;69(2):1072-83.
2001: Philippe J Sansonetti
Rupture, invasion and inflammatory destruction of the intestinal barrier by Shigella, making sense of prokaryote-eukaryote cross-talks.
FEMS microbiology reviews 2001;25(1):3-14.
2000: Kirsten Niebuhr; Noureddine Jouihri; Abdelmounaaïm Allaoui; Pierre GOUNON; Philippe J Sansonetti; Claude Parsot
IpgD, a protein secreted by the type III secretion machinery of Shigella flexneri, is chaperoned by IpgE and implicated in entry focus formation.
Molecular microbiology 2000;38(1):8-19.
2000: Dana J Philpott; S Yamaoka; A Israël; Philippe J Sansonetti
Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):903-14.
2000: Guy Tran Van Nhieu; Raphaëlle Bourdet-Sicard; G Duménil; Ariel Blocker; Philippe J Sansonetti
Bacterial signals and cell responses during Shigella entry into epithelial cells.
Cellular microbiology 2000;2(3):187-93.
2000: Raphaëlle Bourdet-Sicard; Coumaran Egile; Philippe J Sansonetti; Guy Tran Van Nhieu
Diversion of cytoskeletal processes by Shigella during invasion of epithelial cells.
Microbes and infection / Institut Pasteur 2000;2(7):813-9.
2000: Dana J Philpott; Jonathan D Edgeworth; Philippe J Sansonetti
The pathogenesis of Shigella flexneri infection: lessons from in vitro and in vivo studies.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1397):575-86.
2000: Philippe J Sansonetti; Armelle Phalipon; J Arondel; K Thirumalai; S Banerjee; Shizuo Akira; K Takeda; Arturo Zychlinsky
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation.
Immunity 2000;12(5):581-90.
2000: Philippe J Sansonetti
Microbial pathogenesis: new paths into a new millennium.
Trends in microbiology 2000;8(5):196-7.
2000: Kirsten Niebuhr; Philippe J Sansonetti
Invasion of epithelial cells by bacterial pathogens the paradigm of Shigella.
Sub-cellular biochemistry 2000;33():251-87.
1999: Sylvie Mémet; Dhafer Laouini; Jean-Charles Epinat; ST Whiteside; Bertrand Goudeau; Dana J Philpott; Samer kayal; Philippe J Sansonetti; Patrick Berche; Jean M Kanellopoulos; Alain Israël
IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):5994-6005.
1999: Raphaëlle Bourdet-Sicard; M Rüdiger; Brigitte M Jockusch; Pierre GOUNON; Philippe J Sansonetti; Guy Tran Van Nhieu
Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization.
The EMBO journal 1999;18(21):5853-62.
1999: J Arondel; Monique Singer; A Matsukawa; Arturo Zychlinsky; Philippe J Sansonetti
Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental Shigellosis.
Infection and immunity 1999;67(11):6056-66.
1999: Coumaran Egile; TP Loisel; V Laurent; Rong Li; Dominique Pantaloni; Philippe J Sansonetti; Marie-France Carlier
Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility.
The Journal of cell biology 1999;146(6):1319-32.
1999: Anne-Laure Page; H Ohayon; Philippe J Sansonetti; Claude Parsot
The secreted IpaB and IpaC invasins and their cytoplasmic chaperone IpgC are required for intercellular dissemination of Shigella flexneri.
Cellular microbiology 1999;1(2):183-93.
1999: Joëlle Mounier; V Laurent; Alan Hall; Philippe FORT; Marie-France Carlier; Philippe J Sansonetti; Coumaran Egile
Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility.
Journal of cell science 1999;112 ( Pt 13)():2069-80.
1999: Guy Tran Van Nhieu; E Caron; Alan Hall; Philippe J Sansonetti
IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells.
The EMBO journal 1999;18(12):3249-62.
1999: Philippe J Sansonetti; Armelle Phalipon
M cells as ports of entry for enteroinvasive pathogens: mechanisms of interaction, consequences for the disease process.
Seminars in immunology 1999;11(3):193-203.
1999: Edith Gouin; H Gantelet; Coumaran Egile; Iñigo Lasa; H Ohayon; V Villiers; Pierre GOUNON; Philippe J Sansonetti; Pascale Cossart
A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii.
Journal of cell science 1999;112 ( Pt 11)():1697-708.
1999: W L Beatty; Stéphane Méresse; Pierre GOUNON; Jean Davoust; Joëlle Mounier; Philippe J Sansonetti; Jean-Pierre Gorvel
Trafficking of Shigella lipopolysaccharide in polarized intestinal epithelial cells.
The Journal of cell biology 1999;145(4):689-98.
1999: Philippe J Sansonetti; Guy Tran Van Nhieu; Coumaran Egile
Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999;28(3):466-75.
1999: Philippe J Sansonetti; J Arondel; Michel Huerre; A Harada; K Matsushima
Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis.
Infection and immunity 1999;67(3):1471-80.
1999: Guy Tran Van Nhieu; Philippe J Sansonetti
Mechanism of Shigella entry into epithelial cells.
Current opinion in microbiology 1999;2(1):51-5.
1999: Patrice Boquet; Philippe J Sansonetti; Guy Tran Van Nhieu
Rho GTP-binding proteins as targets for microbial pathogens.
Progress in molecular and subcellular biology 1999;22():183-99.
1999: Armelle Phalipon; Philippe J Sansonetti
Microbial-host interactions at mucosal sites. Host response to pathogenic bacteria at mucosal sites.
Current topics in microbiology and immunology 1999;236():163-89.
1998: Hubert Hilbi; Jeremy E Moss; D Hersh; Y Chen; J Arondel; S Banerjee; R A Flavell; J Yuan; Philippe J Sansonetti; Arturo Zychlinsky
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB.
The Journal of biological chemistry 1998;273(49):32895-900.
1998: G Duménil; J C Olivo; S Pellegrini; M Fellous; Philippe J Sansonetti; Guy Tran Van Nhieu
Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells.
The Journal of cell biology 1998;143(4):1003-12.
1998: Philippe J Sansonetti; Coumaran Egile
Molecular bases of epithelial cell invasion by Shigella flexneri.
Antonie van Leeuwenhoek 1998;74(4):191-7.
1998: Z Benjelloun-Touimi; Mustapha Si-Tahar; C Montecucco; Philippe J Sansonetti; Claude Parsot
SepA, the 110 kDa protein secreted by Shigella flexneri: two-domain structure and proteolytic activity.
Microbiology (Reading, England) 1998;144 ( Pt 7)():1815-22.
1998: Brigitte Demers; Philippe J Sansonetti; Claude Parsot
Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins.
The EMBO journal 1998;17(10):2894-903.
1998: Philippe J Sansonetti
Pathogenesis of shigellosis: from molecular and cellular biology of epithelial cell invasion to tissue inflammation and vaccine development.
Japanese journal of medical science & biology 1998;51 Suppl():S69-80.
1998: Philippe J Sansonetti
Molecular and cellular mechanisms of invasion of the intestinal barrier by enteric pathogens. The paradigm of Shigella.
Folia microbiologica 1998;43(3):239-46.
1998: S Bârzu; J Arondel; Sophie Guillot; Philippe J Sansonetti; Armelle Phalipon
Immunogenicity of IpaC-hybrid proteins expressed in the Shigella flexneri 2a vaccine candidate SC602.
Infection and immunity 1998;66(1):77-82.
1997: W L Beatty; Philippe J Sansonetti
Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes.
Infection and immunity 1997;65(11):4395-404.
1997: Armelle Phalipon; Antonella Folgori; J Arondel; G Sgaramella; Paola Fortugno; Riccardo Cortese; Philippe J Sansonetti; Franco Felici
Induction of anti-carbohydrate antibodies by phage library-selected peptide mimics.
European journal of immunology 1997;27(10):2620-5.
1997: P Renesto; Philippe J Sansonetti; Nancy Guillén
Interaction between Entamoeba histolytica and intestinal epithelial cells involves a CD44 cross-reactive protein expressed on the parasite surface.
Infection and immunity 1997;65(10):4330-3.
1997: F K Bahrani; Philippe J Sansonetti; Claude Parsot
Secretion of Ipa proteins by Shigella flexneri: inducer molecules and kinetics of activation.
Infection and immunity 1997;65(10):4005-10.
1997: Philippe J Sansonetti
[Molecular and cellular bases of intestinal epithelial cell invasion by Shigella flexneri].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1997;320(9):729-34.
1997: Guy Tran Van Nhieu; A Ben-Ze'ev; Philippe J Sansonetti
Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin.
The EMBO journal 1997;16(10):2717-29.
1997: Arturo Zychlinsky; Philippe J Sansonetti
Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?
Trends in microbiology 1997;5(5):201-4.
1997: Coumaran Egile; Hélène D'Hauteville; Claude Parsot; Philippe J Sansonetti
SopA, the outer membrane protease responsible for polar localization of IcsA in Shigella flexneri.
Molecular microbiology 1997;23(5):1063-73.
1997: Joëlle Mounier; F K Bahrani; Philippe J Sansonetti
Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent.
Infection and immunity 1997;65(2):774-82.
1997: C De Geyter; B Vogt; Z Benjelloun-Touimi; Philippe J Sansonetti; Jean-Marie Ruysschaert; Claude Parsot; Véronique Cabiaux
Purification of IpaC, a protein involved in entry of Shigella flexneri into epithelial cells and characterization of its interaction with lipid membranes.
FEBS letters 1997;400(2):149-54.
1997: Hubert Hilbi; Arturo Zychlinsky; Philippe J Sansonetti
Macrophage apoptosis in microbial infections.
Parasitology 1997;115 Suppl():S79-87.
1996: Arturo Zychlinsky; K Thirumalai; J Arondel; J Robert Cantey; AO Aliprantis; Philippe J Sansonetti
In vivo apoptosis in Shigella flexneri infections.
Infection and immunity 1996;64(12):5357-65.
1996: N J Mantis; Philippe J Sansonetti
The nadB gene of Salmonella typhimurium complements the nicotinic acid auxotrophy of Shigella flexneri.
Molecular & general genetics : MGG 1996;252(5):626-9.
1996: Philippe J Sansonetti; J Arondel; J Robert Cantey; M C Prévost; Michel Huerre
Infection of rabbit Peyer's patches by Shigella flexneri: effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium.
Infection and immunity 1996;64(7):2752-64.
1996: R Ménard; C Dehio; Philippe J Sansonetti
Bacterial entry into epithelial cells: the paradigm of Shigella.
Trends in microbiology 1996;4(6):220-6.
1996: Claude Parsot; Philippe J Sansonetti
Invasion and the pathogenesis of Shigella infections.
Current topics in microbiology and immunology 1996;209():25-42.
1995: C Kocks; J B Marchand; Edith Gouin; H d'Hauteville; Philippe J Sansonetti; Marie-France Carlier; Pascale Cossart
The unrelated surface proteins ActA of Listeria monocytogenes and IcsA of Shigella flexneri are sufficient to confer actin-based motility on Listeria innocua and Escherichia coli respectively.
Molecular microbiology 1995;18(3):413-23.
1995: A Allaoui; Philippe J Sansonetti; R Ménard; S Barzu; Joëlle Mounier; Armelle Phalipon; Claude Parsot
MxiG, a membrane protein required for secretion of Shigella spp. Ipa invasins: involvement in entry into epithelial cells and in intercellular dissemination.
Molecular microbiology 1995;17(3):461-70.
1995: Philippe J Sansonetti; J Arondel; Jean-Marc Cavaillon; Michel Huerre
Role of interleukin-1 in the pathogenesis of experimental shigellosis.
The Journal of clinical investigation 1995;96(2):884-92.
1995: Z Benjelloun-Touimi; Philippe J Sansonetti; Claude Parsot
SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion.
Molecular microbiology 1995;17(1):123-35.
1995: Philippe J Sansonetti
[Prevention of diarrheal diseases and oral vaccination].
La Revue du praticien 1995;45(12):1512-3.
1995: C Dehio; M C Prévost; Philippe J Sansonetti
Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway.
The EMBO journal 1995;14(11):2471-82.
1995: T Adam; Monique Arpin; M C Prévost; Pierre GOUNON; Philippe J Sansonetti
Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells.
The Journal of cell biology 1995;129(2):367-81.
1995: Claude Parsot; R Ménard; Pierre GOUNON; Philippe J Sansonetti
Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structures.
Molecular microbiology 1995;16(2):291-300.
1994: Marcia B Goldberg; J A Theriot; Philippe J Sansonetti
Regulation of surface presentation of IcsA, a Shigella protein essential to intracellular movement and spread, is growth phase dependent.
Infection and immunity 1994;62(12):5664-8.
1994: O J Perdomo; Jean-Marc Cavaillon; Michel Huerre; H Ohayon; Pierre GOUNON; Philippe J Sansonetti
Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis.
The Journal of experimental medicine 1994;180(4):1307-19.
1994: Arturo Zychlinsky; Catherine Fitting; Jean-Marc Cavaillon; Philippe J Sansonetti
Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri.
The Journal of clinical investigation 1994;94(3):1328-32.
1994: Armelle Phalipon; Pierre Michetti; M Kaufmann; Jean-Marc Cavaillon; Michel Huerre; J P Kraehenbuhl; Philippe J Sansonetti
Protection against invasion of the mouse pulmonary epithelium by a monoclonal IgA directed against Shigella flexneri lipopolysaccharide.
Annals of the New York Academy of Sciences 1994;730():356-8.
1994: Arturo Zychlinsky; J J Perdomo; Philippe J Sansonetti
Molecular and cellular mechanisms of tissue invasion by Shigella flexneri.
Annals of the New York Academy of Sciences 1994;730():197-208.
1994: Philippe J Sansonetti
Shigella flexneri: from in vitro invasion of epithelial cells to infection of the intestinal barrier.
Biochemical Society transactions 1994;22(2):295-8.
1994: Philippe J Sansonetti; Joëlle Mounier; M C Prévost; R M Mège
Cadherin expression is required for the spread of Shigella flexneri between epithelial cells.
Cell 1994;76(5):829-39.
1994: Philippe J Sansonetti
[Vaccination against the enterobacteria responsible for enteric infections].
Annales de gastroentérologie et d'hépatologie 1994;30(2):60-3.
1994: Arturo Zychlinsky; B Kenny; R Ménard; M C Prévost; I Barry Holland; Philippe J Sansonetti
IpaB mediates macrophage apoptosis induced by Shigella flexneri.
Molecular microbiology 1994;11(4):619-27.
1994: J J Perdomo; Pierre GOUNON; Philippe J Sansonetti
Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri.
The Journal of clinical investigation 1994;93(2):633-43.
1994: R Ménard; Philippe J Sansonetti
Shigella flexneri: isolation of noninvasive mutants of gram-negative pathogens.
Methods in enzymology 1994;236():493-509.
1993: Marcia B Goldberg; Philippe J Sansonetti
Shigella subversion of the cellular cytoskeleton: a strategy for epithelial colonization.
Infection and immunity 1993;61(12):4941-6.
1993: Philippe J Sansonetti
[Vaccination against the enterobacteriaceae responsible for enteric infections].
Bulletin de l'Académie nationale de médecine 1993;177(8):1401-7; discussion 1407-8.
1993: P M Trotot; Philippe J Sansonetti; Françoise Gray; J M Bigot; C Sandoz-Tronca
[Early involvement of the central nervous system in HIV infection: screening by MRI (a 5-year follow-up)].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1993;316(10):1270-3.
1993: R Ménard; Philippe J Sansonetti; Claude Parsot
Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells.
Journal of bacteriology 1993;175(18):5899-906.
1993: Maria Bernardini; M G Sanna; A Fontaine; Philippe J Sansonetti
OmpC is involved in invasion of epithelial cells by Shigella flexneri.
Infection and immunity 1993;61(9):3625-35.
1993: Arturo Zychlinsky; B Kenny; Marie-Christine Prevost; I Barry Holland; Philippe J Sansonetti
The ipaB gene of Shigella flexneri and macrophage-programmed cell death.
Infectious agents and disease 1993;2(4):212-4.
1993: Marcia B Goldberg; O Barzu; Claude Parsot; Philippe J Sansonetti
Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement.
Infectious agents and disease 1993;2(4):210-1.
1993: Philippe J Sansonetti
Molecular mechanisms of cell and tissue invasion by Shigella flexneri.
Infectious agents and disease 1993;2(4):201-6.
1993: A Allaoui; R Ménard; Philippe J Sansonetti; Claude Parsot
Characterization of the Shigella flexneri ipgD and ipgF genes, which are located in the proximal part of the mxi locus.
Infection and immunity 1993;61(5):1707-14.
1993: Marcia B Goldberg; Octavian Bârzu; Claude Parsot; Philippe J Sansonetti
Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement.
Journal of bacteriology 1993;175(8):2189-96.
1993: A Allaoui; Philippe J Sansonetti; Claude Parsot
MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins.
Molecular microbiology 1993;7(1):59-68.
1992: A Allaoui; Philippe J Sansonetti; Claude Parsot
MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins.
Journal of bacteriology 1992;174(23):7661-9.
1992: Philippe J Sansonetti
[Physiopathology of intestinal Salmonella infection].
La Revue du praticien 1992;42(18):2263-7.
1992: M C Prévost; M Lesourd; Monique Arpin; F Vernel; Joëlle Mounier; R Hellio; Philippe J Sansonetti
Unipolar reorganization of F-actin layer at bacterial division and bundling of actin filaments by plastin correlate with movement of Shigella flexneri within HeLa cells.
Infection and immunity 1992;60(10):4088-99.
1992: Arturo Zychlinsky; Marie-Christine Prevost; Philippe J Sansonetti
Shigella flexneri induces apoptosis in infected macrophages.
Nature 1992;358(6382):167-9.
1992: A Allaoui; Joëlle Mounier; M C Prévost; Philippe J Sansonetti; Claude Parsot
icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread.
Molecular microbiology 1992;6(12):1605-16.
1992: N High; Joëlle Mounier; M C Prévost; Philippe J Sansonetti
IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole.
The EMBO journal 1992;11(5):1991-9.
1992: Armelle Phalipon; J Arondel; Farida Nato; S Rouyre; JC Mazie; Philippe J Sansonetti
Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri.
Infection and immunity 1992;60(5):1919-26.
1992: H d'Hauteville; Philippe J Sansonetti
Phosphorylation of IcsA by cAMP-dependent protein kinase and its effect on intracellular spread of Shigella flexneri.
Molecular microbiology 1992;6(7):833-41.
1992: T Vasselon; Joëlle Mounier; R Hellio; Philippe J Sansonetti
Movement along actin filaments of the perijunctional area and de novo polymerization of cellular actin are required for Shigella flexneri colonization of epithelial Caco-2 cell monolayers.
Infection and immunity 1992;60(3):1031-40.
1992: Joëlle Mounier; T Vasselon; R Hellio; M Lesourd; Philippe J Sansonetti
Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole.
Infection and immunity 1992;60(1):237-48.
1992: Philippe J Sansonetti
[Molecular and cellular bases of the virulence of Shigella flexneri].
Annales de gastroentérologie et d'hépatologie 1992;28(1):44-7.
1992: Philippe J Sansonetti
Molecular and cellular biology of Shigella flexneri invasiveness: from cell assay systems to shigellosis.
Current topics in microbiology and immunology 1992;180():1-19.
1992: R Verdon; David Mirelman; Philippe J Sansonetti
A model of interaction between Entamoeba histolytica and Shigella flexneri.
Research in microbiology 1992;143(1):67-74.
1991: Philippe J Sansonetti; J Arondel; A Fontaine; H d'Hauteville; Maria Bernardini
OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis.
Vaccine 1991;9(6):416-22.
1991: Philippe J Sansonetti
[Molecular and cellular bases of Shigella flexneri virulence].
Bulletin de l'Académie nationale de médecine 1991;175(6):803-9; discussion 809-10.
1991: T Vasselon; Joëlle Mounier; Marie-Christine Prevost; R Hellio; Philippe J Sansonetti
Stress fiber-based movement of Shigella flexneri within cells.
Infection and immunity 1991;59(5):1723-32.
1991: Philippe J Sansonetti
Genetic and molecular basis of epithelial cell invasion by Shigella species.
Reviews of infectious diseases 1991;13 Suppl 4():S285-92.
1991: T Vasselon; Philippe J Sansonetti; Xavier Nassif
Nucleotide sequence of rmpB, a Klebsiella pneumoniae gene that positively controls, colanic biosynthesis in Escherichia coli.
Research in microbiology 1991;142(1):47-54.
1990: M Kuhn; M C Prévost; Joëlle Mounier; Philippe J Sansonetti
A nonvirulent mutant of Listeria monocytogenes does not move intracellularly but still induces polymerization of actin.
Infection and immunity 1990;58(11):3477-86.
1990: Maria Bernardini; A Fontaine; Philippe J Sansonetti
The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri.
Journal of bacteriology 1990;172(11):6274-81.
1990: A Fontaine; J Arondel; Philippe J Sansonetti
Construction and evaluation of live attenuated vaccine strains of Shigella flexneri and Shigella dysenteriae 1.
Research in microbiology 1990;141(7-8):907-12.
1990: Joëlle Mounier; A Ryter; M Coquis-Rondon; Philippe J Sansonetti
Intracellular and cell-to-cell spread of Listeria monocytogenes involves interaction with F-actin in the enterocytelike cell line Caco-2.
Infection and immunity 1990;58(4):1048-58.
1990: V L Franzon; J Arondel; Philippe J Sansonetti
Contribution of superoxide dismutase and catalase activities to Shigella flexneri pathogenesis.
Infection and immunity 1990;58(2):529-35.
1989: Philippe Clerc; Philippe J Sansonetti
Evidence for clathrin mobilization during directed phagocytosis of Shigella flexneri by HEp2 cells.
Microbial pathogenesis 1989;7(5):329-36.
1989: Xavier Nassif; N Honoré; T Vasselon; S T Cole; Philippe J Sansonetti
Positive control of colanic acid synthesis in Escherichia coli by rmpA and rmpB, two virulence-plasmid genes of Klebsiella pneumoniae.
Molecular microbiology 1989;3(10):1349-59.
1989: Philippe J Sansonetti; J Arondel
Construction and evaluation of a double mutant of Shigella flexneri as a candidate for oral vaccination against shigellosis.
Vaccine 1989;7(5):443-50.
1989: Philippe Clerc; B Berthon; Michel Claret; Philippe J Sansonetti
Internalization of Shigella flexneri into HeLa cells occurs without an increase in cytosolic Ca2+ concentration.
Infection and immunity 1989;57(9):2919-22.
1989: Maria Bernardini; Joëlle Mounier; H d'Hauteville; M Coquis-Rondon; Philippe J Sansonetti
Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3867-71.
1989: X Nassif; J M Fournier; J Arondel; Philippe J Sansonetti
Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor.
Infection and immunity 1989;57(2):546-52.
1988: A Fontaine; J Arondel; Philippe J Sansonetti
Role of Shiga toxin in the pathogenesis of bacillary dysentery, studied by using a Tox- mutant of Shigella dysenteriae 1.
Infection and immunity 1988;56(12):3099-109.
1988: B Baudry; M Kaczorek; Philippe J Sansonetti
Nucleotide sequence of the invasion plasmid antigen B and C genes (ipaB and ipaC) of Shigella flexneri.
Microbial pathogenesis 1988;4(5):345-57.
1988: A T Maurelli; Philippe J Sansonetti
Identification of a chromosomal gene controlling temperature-regulated expression of Shigella virulence.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2820-4.
1988: P M Trotot; Emmanuel Alain Cabanis; R Lavayssière; Philippe J Sansonetti; C Sandoz-Tronca; A E Cabee; Jean TAMRAZ; C Stoffels; P M Levillain
[Cerebral MRI in the study of prognostic factors in AIDS. Hypotheses from tests on 15 patients].
Journal de radiologie 1988;69(3):193-6.
1988: P M Trotot; Philippe J Sansonetti; R Levillain; Emmanuel Alain Cabanis; R Lavayssiere; C Sandoz-Tronca
[Magnetic resonance imaging: early detection of involvement of the central nervous system in acquired immunodeficiency syndrome].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1988;307(1):1-4.
1988: H D'Hauteville; R Vicens; P Coulanges; Philippe J Sansonetti
[Dysentery caused by Shigella and enteroinvasive Escherichia coli. Diagnosis by DNA/DNA hybridization].
Archives de l'Institut Pasteur de Madagascar 1988;54(1):75-82.
1988: Philippe J Sansonetti
Molecular basis of invasion of eucaryotic cells by Shigella.
Antonie van Leeuwenhoek 1988;54(5):389-93.
1988: Philippe Clerc; B Baudry; Philippe J Sansonetti
Molecular mechanisms of entry, intracellular multiplication and killing of host cells by shigellae.
Current topics in microbiology and immunology 1988;138():3-13.
1987: B Baudry; A T Maurelli; Philippe Clerc; J C Sadoff; Philippe J Sansonetti
Localization of plasmid loci necessary for the entry of Shigella flexneri into HeLa cells, and characterization of one locus encoding four immunogenic polypeptides.
Journal of general microbiology 1987;133(12):3403-13.
1987: Philippe Clerc; Philippe J Sansonetti
Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation.
Infection and immunity 1987;55(11):2681-8.
1987: Philippe J Sansonetti; Joëlle Mounier
Metabolic events mediating early killing of host cells infected by Shigella flexneri.
Microbial pathogenesis 1987;3(1):53-61.
1987: Philippe Clerc; A Ryter; Joëlle Mounier; Philippe J Sansonetti
Plasmid-mediated early killing of eucaryotic cells by Shigella flexneri as studied by infection of J774 macrophages.
Infection and immunity 1987;55(3):521-7.
1986: Philippe Clerc; A Ryter; Joëlle Mounier; Philippe J Sansonetti
Plasmid-mediated intracellular multiplication of Shigella flexneri.
Annales de l'Institut Pasteur. Microbiologie 1986;137A(3):315-20.
1986: Philippe Clerc; B Baudry; Philippe J Sansonetti
Plasmid-mediated contact haemolytic activity in Shigella species: correlation with penetration into HeLa cells.
Annales de l'Institut Pasteur. Microbiologie 1986;137A(3):267-78.
1986: Philippe J Sansonetti; A Ryter; Philippe Clerc; A T Maurelli; Joëlle Mounier
Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis.
Infection and immunity 1986;51(2):461-9.
1985: A T Maurelli; B Baudry; H d'Hauteville; T L Hale; Philippe J Sansonetti
Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri.
Infection and immunity 1985;49(1):164-71.