FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Silvia Santamarina-Fojo

Research Profile

Living Beings

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Marcelo J A Amar; Robert D Shamburek; Boris Vaisman; Catherine L Knapper; Bernhard Foger; Robert F Hoyt; Silvia Santamarina-Fojo; Hollis B Brewer; Alan T Remaley
Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein.
Lita Freeman; Marcelo J A Amar; Robert D Shamburek; Beverly Paigen; H Bryan Brewer; Silvia Santamarina-Fojo; Herminia González-Navarro
Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice.
Federica Basso; Lita A Freeman; Carol Ko; Charles Joyce; Marcelo J A Amar; Robert D Shamburek; Terese Tansey; Fairwell Thomas; Justina Wu; Beverly Paigen; Alan T Remaley; Silvia Santamarina-Fojo; H Bryan Brewer
Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Silvia Santamarina-Fojo (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2009: Marcelo J A Amar; Robert D Shamburek; Boris Vaisman; Catherine L Knapper; Bernhard Foger; Robert F Hoyt; Silvia Santamarina-Fojo; Hollis B Brewer; Alan T Remaley
Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein.
Metabolism: clinical and experimental 2009;58(4):568-75.
2007: Lita Freeman; Marcelo J A Amar; Robert D Shamburek; Beverly Paigen; H Bryan Brewer; Silvia Santamarina-Fojo; Herminia González-Navarro
Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice.
Journal of lipid research 2007;48(1):104-13.
2007: Federica Basso; Lita A Freeman; Carol Ko; Charles Joyce; Marcelo J A Amar; Robert D Shamburek; Terese Tansey; Fairwell Thomas; Justina Wu; Beverly Paigen; Alan T Remaley; Silvia Santamarina-Fojo; H Bryan Brewer
Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited.
Journal of lipid research 2007;48(1):114-26.
2006: Federica Basso; Marcelo J A Amar; Elke M Wagner; Boris Vaisman; Beverly Paigen; Silvia Santamarina-Fojo; Alan T Remaley
Enhanced ABCG1 expression increases atherosclerosis in LDLr-KO mice on a western diet.
Biochemical and biophysical research communications 2006;351(2):398-404.
2006: Grace L Guo; Silvia Santamarina-Fojo; Taro E Akiyama; Marcelo J A Amar; Beverly Paigen; Bryan Brewer; Frank J Gonzalez
Effects of FXR in foam-cell formation and atherosclerosis development.
Biochimica et biophysica acta 2006;1761(12):1401-9.
2006: Charles W Joyce; Elke M Wagner; Federica Basso; Marcelo J A Amar; Lita A Freeman; Robert D Shamburek; Catherine L Knapper; Jafri Syed; Justina Wu; Boris Vaisman; Jamila Fruchart-Najib; Eric M Billings; Beverly Paigen; Alan T Remaley; Silvia Santamarina-Fojo; H Bryan Brewer
ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis.
The Journal of biological chemistry 2006;281(44):33053-65.
2005: Steven L Sabol; H Bryan Brewer; Silvia Santamarina-Fojo
The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver.
Journal of lipid research 2005;46(10):2151-67.
2004: Herminia González-Navarro; Zengxuan Nong; Marcelo J A Amar; Robert D Shamburek; Jamila Najib-Fruchart; Beverly Paigen; H Bryan Brewer; Silvia Santamarina-Fojo
The ligand-binding function of hepatic lipase modulates the development of atherosclerosis in transgenic mice.
The Journal of biological chemistry 2004;279(44):45312-21.
2004: Silvia Santamarina-Fojo; Herminia González-Navarro; Lita Freeman; Elke Wagner; Zengxuan Nong
Hepatic lipase, lipoprotein metabolism, and atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1750-4.
2004: Lita A Freeman; Arion Kennedy; Justina Wu; Samantha Bark; Alan T Remaley; Silvia Santamarina-Fojo; H Bryan Brewer
The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter.
Journal of lipid research 2004;45(7):1197-206.
2004: Justina E Wu; Federica Basso; Robert D Shamburek; Marcelo J A Amar; Boris Vaisman; Gergely Szakacs; Charles Joyce; Terese Tansey; Lita Freeman; Beverly Paigen; Fairwell Thomas; H Bryan Brewer; Silvia Santamarina-Fojo
Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice.
The Journal of biological chemistry 2004;279(22):22913-25.
2004: Edward B Neufeld; John Anthony Stonik; Stephen J Demosky; Catherine L Knapper; Christian A Combs; Adele Cooney; Marcy Comly; Nancy K Dwyer; Joan Blanchette-Mackie; Alan T Remaley; Silvia Santamarina-Fojo; H Bryan Brewer
The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.
The Journal of biological chemistry 2004;279(15):15571-8.
2003: H Bryan Brewer; Silvia Santamarina-Fojo
Clinical significance of high-density lipoproteins and the development of atherosclerosis: focus on the role of the adenosine triphosphate-binding cassette protein A1 transporter.
The American journal of cardiology 2003;92(4B):10K-16K.
2003: Zengxuan Nong; Herminia Gonzalez-Navarro; Marcelo J A Amar; Lita Freeman; Catherine L Knapper; Edward B Neufeld; Beverly Paigen; Robert F Hoyt; Jamila Fruchart-Najib; Silvia Santamarina-Fojo
Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice.
The Journal of clinical investigation 2003;112(3):367-78.
2003: Charles Joyce; Lita Freeman; H Bryan Brewer; Silvia Santamarina-Fojo
Study of ABCA1 function in transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(6):965-71.
2003: H Bryan Brewer; Silvia Santamarina-Fojo
New insights into the role of the adenosine triphosphate-binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transport.
The American journal of cardiology 2003;91(7A):3E-11E.
2003: Alan T Remaley; Fairwell Thomas; John Anthony Stonik; Stephen J Demosky; Samantha Bark; Edward B Neufeld; Alexander V Bocharov; Tatyana G Vishnyakova; Amy P Patterson; Thomas L Eggerman; Silvia Santamarina-Fojo; H Bryan Brewer
Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway.
Journal of lipid research 2003;44(4):828-36.
2003: Federica Basso; Lita Freeman; Catherine L Knapper; Alan T Remaley; John Anthony Stonik; Edward B Neufeld; Terese Tansey; Marcelo J A Amar; Jamila Fruchart-Najib; Nicolas Duverger; Silvia Santamarina-Fojo; H Bryan Brewer
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.
Journal of lipid research 2003;44(2):296-302.
2002: Edward B Neufeld; Stephen J Demosky; John Anthony Stonik; Christian A Combs; Alan T Remaley; Nicolas Duverger; Silvia Santamarina-Fojo; H Bryan Brewer
The ABCA1 transporter functions on the basolateral surface of hepatocytes.
Biochemical and biophysical research communications 2002;297(4):974-9.
2002: Alan T Remaley; Samantha Bark; Avram D Walts; Lita Freeman; Sergey Shulenin; Tarmo Annilo; Eric Elgin; Hope E Rhodes; Charles Joyce; Michael Dean; Silvia Santamarina-Fojo; H Bryan Brewer
Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster.
Biochemical and biophysical research communications 2002;295(2):276-82.
2002: Herminia González-Navarro; Zengxuan Nong; Lita Freeman; André Bensadoun; Katherine Peterson; Silvia Santamarina-Fojo
Identification of mouse and human macrophages as a site of synthesis of hepatic lipase.
Journal of lipid research 2002;43(5):671-5.
2002: Jonas Peterson; Amir F Ayyobi; Yuanhong Ma; Howard Henderson; Manuel Reina; Samir S Deeb; Silvia Santamarina-Fojo; Michael R Hayden; John D Brunzell
Structural and functional consequences of missense mutations in exon 5 of the lipoprotein lipase gene.
Journal of lipid research 2002;43(3):398-406.
2002: Xiao-Ping Yang; Lita A Freeman; Catherine L Knapper; Marcelo J A Amar; Alan T Remaley; H Bryan Brewer; Silvia Santamarina-Fojo
The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene.
Journal of lipid research 2002;43(2):297-306.
2002: Charles W Joyce; Marcelo J A Amar; Gilles Lambert; Boris Vaisman; Beverly Paigen; Jamila Najib-Fruchart; Robert F Hoyt; Edward D Neufeld; Alan T Remaley; Donald S Fredrickson; H Bryan Brewer; Silvia Santamarina-Fojo
The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):407-12.
2001: AM Bérard; M Clerc; B Brewer; Silvia Santamarina-Fojo
A normal rate of cellular cholesterol removal can be mediated by plasma from a patient with familial lecithin-cholesterol acyltransferase (LCAT) deficiency.
Clinica chimica acta; international journal of clinical chemistry 2001;314(1-2):131-9.
2001: Silvia Santamarina-Fojo; Alan T Remaley; Edward B Neufeld; H Bryan Brewer
Regulation and intracellular trafficking of the ABCA1 transporter.
Journal of lipid research 2001;42(9):1339-45.
2001: Edward B Neufeld; Alan T Remaley; Stephen J Demosky; John Anthony Stonik; Adele Cooney; Marcy Comly; Nancy K Dwyer; Mei Zhang; Joan Blanchette-Mackie; Silvia Santamarina-Fojo; H Bryan Brewer
Cellular localization and trafficking of the human ABCA1 transporter.
The Journal of biological chemistry 2001;276(29):27584-90.
2001: Boris Vaisman; Gilles Lambert; Marcelo J A Amar; Charles Joyce; T Ito; Robert D Shamburek; William Cain; Jamila Fruchart-Najib; E D Neufeld; Alan T Remaley; H Bryan Brewer; Silvia Santamarina-Fojo
ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice.
The Journal of clinical investigation 2001;108(2):303-9.
2001: Gilles Lambert; N Sakai; Boris Vaisman; Edward B Neufeld; Benoit Marteyn; C C Chan; Beverly Paigen; Enrico Lupia; A Thomas; Liliane J Striker; Joan Blanchette-Mackie; Gyorgy Csako; John N Brady; R Costello; Gary E Striker; Alan T Remaley; H Bryan Brewer; Silvia Santamarina-Fojo
Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.
The Journal of biological chemistry 2001;276(18):15090-8.
2001: Alan T Remaley; John Anthony Stonik; Stephen J Demosky; Edward B Neufeld; Alexander V Bocharov; Tatyana G Vishnyakova; Thomas L Eggerman; Amy P Patterson; Nicolas Duverger; Silvia Santamarina-Fojo; H Bryan Brewer
Apolipoprotein specificity for lipid efflux by the human ABCAI transporter.
Biochemical and biophysical research communications 2001;280(3):818-23.
2000: Silvia Santamarina-Fojo; K Peterson; Catherine L Knapper; Y Qiu; Lita Freeman; J F Cheng; J Osorio; Alan T Remaley; X P Yang; C Haudenschild; C Prades; Giovanna Chimini; E Blackmon; T Francois; Nicolas Duverger; E M Rubin; Marie Rosier; Patrice DENEFLE; Donald S Fredrickson; H Bryan Brewer
Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(14):7987-92.
2000: Silvia Santamarina-Fojo; Gilles Lambert; Jeffrey M Hoeg; H Bryan Brewer
Lecithin-cholesterol acyltransferase: role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosis.
Current opinion in lipidology 2000;11(3):267-75.
2000: Gilles Lambert; Marcelo J A Amar; P Martin; Jamila Fruchart-Najib; B Föger; Robert D Shamburek; H Bryan Brewer; Silvia Santamarina-Fojo
Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo.
Journal of lipid research 2000;41(5):667-72.
2000: KA Dugi; Marcelo J A Amar; CC Haudenschild; Robert D Shamburek; André Bensadoun; Robert F Hoyt; Jamila Fruchart-Najib; Z Madj; H Bryan Brewer; Silvia Santamarina-Fojo
In vivo evidence for both lipolytic and nonlipolytic function of hepatic lipase in the metabolism of HDL.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(3):793-800.
2000: Margaret E Brousseau; RD Kauffman; edward herderick; Stephen J Demosky; W Evans; S Marcovina; Silvia Santamarina-Fojo; H Bryan Brewer; Jeffrey M Hoeg
LCAT modulates atherogenic plasma lipoproteins and the extent of atherosclerosis only in the presence of normal LDL receptors in transgenic rabbits.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):450-8.
2000: Silvia Santamarina-Fojo; CC Haudenschild
Role of hepatic and lipoprotein lipase in lipoprotein metabolism and atherosclerosis: studies in transgenic and knockout animal models and somatic gene transfer.
International journal of tissue reactions 2000;22(2-3):39-47.
1999: B Föger; M Chase; Marcelo J A Amar; Boris Vaisman; Robert D Shamburek; Beverly Paigen; Jamila Fruchart-Najib; J A Paiz; Christian A Koch; Robert F Hoyt; H Bryan Brewer; Silvia Santamarina-Fojo
Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice.
The Journal of biological chemistry 1999;274(52):36912-20.
1999: Alan T Remaley; Stephan Rust; Marie Rosier; Catherine L Knapper; L Naudin; cyril broccardo; K M Peterson; Christian A Koch; Isabelle Arnould; C Prades; Nicolas Duverger; Harald Funke; G Assman; M Dinger; Michael Dean; Giovanna Chimini; Silvia Santamarina-Fojo; Donald S Fredrickson; Patrice DENEFLE; H Bryan Brewer
Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12685-90.
1999: Gilles Lambert; M B Chase; KA Dugi; André Bensadoun; H Bryan Brewer; Silvia Santamarina-Fojo
Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor B1.
Journal of lipid research 1999;40(7):1294-303.
1998: Marcelo J A Amar; KA Dugi; CC Haudenschild; Robert D Shamburek; B Foger; M Chase; André Bensadoun; Robert F Hoyt; H Bryan Brewer; Silvia Santamarina-Fojo
Hepatic lipase facilitates the selective uptake of cholesteryl esters from remnant lipoproteins in apoE-deficient mice.
Journal of lipid research 1998;39(12):2436-42.
1998: Silvia Santamarina-Fojo
The familial chylomicronemia syndrome.
Endocrinology and metabolism clinics of North America 1998;27(3):551-67, viii.
1998: Margaret E Brousseau; J Wang; Stephen J Demosky; Boris Vaisman; GD Talley; Silvia Santamarina-Fojo; H Bryan Brewer; Jeffrey M Hoeg
Correction of hypoalphalipoproteinemia in LDL receptor-deficient rabbits by lecithin:cholesterol acyltransferase.
Journal of lipid research 1998;39(8):1558-67.
1998: Silvia Santamarina-Fojo; CC Haudenschild; Marcelo J A Amar
The role of hepatic lipase in lipoprotein metabolism and atherosclerosis.
Current opinion in lipidology 1998;9(3):211-9.
1997: Margaret E Brousseau; Silvia Santamarina-Fojo; Boris Vaisman; D Applebaum-Bowden; AM Bérard; GD Talley; H Bryan Brewer; Jeffrey M Hoeg
Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits: LDL metabolism and HDL metabolism are affected in a gene dose-dependent manner.
Journal of lipid research 1997;38(12):2537-47.
1997: B Föger; Silvia Santamarina-Fojo; Robert D Shamburek; C L Parrot; GD Talley; H Bryan Brewer
Plasma phospholipid transfer protein. Adenovirus-mediated overexpression in mice leads to decreased plasma high density lipoprotein (HDL) and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL.
The Journal of biological chemistry 1997;272(43):27393-400.
1997: KA Dugi; Boris Vaisman; N Sakai; Catherine L Knapper; Susan M Meyn; H Bryan Brewer; Silvia Santamarina-Fojo
Adenovirus-mediated expression of hepatic lipase in LCAT transgenic mice.
Journal of lipid research 1997;38(9):1822-32.
1997: M Rouis; KA Dugi; L Previato; Amy P Patterson; J D Brunzell; H Bryan Brewer; Silvia Santamarina-Fojo
Therapeutic response to medium-chain triglycerides and omega-3 fatty acids in a patient with the familial chylomicronemia syndrome.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(7):1400-6.
1997: AM Bérard; B Föger; Alan T Remaley; Robert D Shamburek; Boris Vaisman; GD Talley; Beverly Paigen; Robert F Hoyt; S Marcovina; H Bryan Brewer; Silvia Santamarina-Fojo
High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase.
Nature medicine 1997;3(7):744-9.
1997: N Sakai; Boris Vaisman; Christian A Koch; Robert F Hoyt; Susan M Meyn; GD Talley; J A Paiz; H Bryan Brewer; Silvia Santamarina-Fojo
Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency.
The Journal of biological chemistry 1997;272(11):7506-10.
1997: KA Dugi; IM Feuerstein; S Hill; J Shih; Silvia Santamarina-Fojo; H Bryan Brewer; Jeffrey M Hoeg
Lipoprotein lipase correlates positively and hepatic lipase inversely with calcific atherosclerosis in homozygous familial hypercholesterolemia.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(2):354-64.
1996: D R Brown; Margaret E Brousseau; Robert D Shamburek; GD Talley; S Meyn; S J Demosky; Silvia Santamarina-Fojo; H Bryan Brewer; Jeffrey M Hoeg
Adenoviral delivery of low-density lipoprotein receptors to hyperlipidemic rabbits: receptor expression modulates high-density lipoproteins.
Metabolism: clinical and experimental 1996;45(12):1447-57.
1996: J Kobayashi; D Applebaum-Bowden; KA Dugi; D R Brown; V S Kashyap; C Parrott; C Duarte; N Maeda; Silvia Santamarina-Fojo
Analysis of protein structure-function in vivo. Adenovirus-mediated transfer of lipase lid mutants in hepatic lipase-deficient mice.
The Journal of biological chemistry 1996;271(42):26296-301.
1996: Jeffrey M Hoeg; Silvia Santamarina-Fojo; A M Bérard; J Fredrick Cornhill; edward herderick; S H Feldman; Christian Haudenschild; Boris Vaisman; Robert F Hoyt; S J Demosky; R D Kauffman; C M Hazel; Santica M Marcovina; H Bryan Brewer
Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11448-53.
1996: N Sakai; Silvia Santamarina-Fojo; S Yamashita; Y Matsuzawa; H Bryan Brewer
Exon 10 skipping caused by intron 10 splice donor site mutation in cholesteryl ester transfer protein gene results in abnormal downstream splice site selection.
Journal of lipid research 1996;37(10):2065-73.
1996: K Brand; KA Dugi; J D Brunzell; D N Nevin; Silvia Santamarina-Fojo
A novel A-->G mutation in intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency.
Journal of lipid research 1996;37(6):1213-23.
1996: Margaret E Brousseau; Silvia Santamarina-Fojo; Loren A Zech; A M Bérard; Boris Vaisman; S M Meyn; D Powell; H Bryan Brewer; Jeffrey M Hoeg
Hyperalphalipoproteinemia in human lecithin cholesterol acyltransferase transgenic rabbits. In vivo apolipoprotein A-I catabolism is delayed in a gene dose-dependent manner.
The Journal of clinical investigation 1996;97(8):1844-51.
1996: Mustapha Rouis; P Lohse; KA Dugi; P Lohse; O U Beg; R Ronan; GD Talley; J D Brunzell; Silvia Santamarina-Fojo
Homozygosity for two point mutations in the lipoprotein lipase (LPL) gene in a patient with familial LPL deficiency: LPL(Asp9-->Asn, Tyr262-->His).
Journal of lipid research 1996;37(3):651-61.
1996: Jeffrey M Hoeg; Boris Vaisman; S J Demosky; S M Meyn; GD Talley; Robert F Hoyt; S Feldman; A M Bérard; N Sakai; D Wood; Margaret E Brousseau; S Marcovina; H Bryan Brewer; Silvia Santamarina-Fojo
Lecithin:cholesterol acyltransferase overexpression generates hyperalpha-lipoproteinemia and a nonatherogenic lipoprotein pattern in transgenic rabbits.
The Journal of biological chemistry 1996;271(8):4396-402.
1996: D Applebaum-Bowden; J Kobayashi; V S Kashyap; D R Brown; A Berard; S Meyn; C Parrott; N Maeda; Robert D Shamburek; H Bryan Brewer; Silvia Santamarina-Fojo
Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endothelium.
The Journal of clinical investigation 1996;97(3):799-805.
1995: KA Dugi; H L Dichek; Silvia Santamarina-Fojo
Human hepatic and lipoprotein lipase: the loop covering the catalytic site mediates lipase substrate specificity.
The Journal of biological chemistry 1995;270(43):25396-401.
1995: V S Kashyap; Silvia Santamarina-Fojo; D R Brown; C L Parrott; D Applebaum-Bowden; S Meyn; GD Talley; Beverly Paigen; Nobuyo Maeda; H Bryan Brewer
Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors.
The Journal of clinical investigation 1995;96(3):1612-20.
1995: HARVEY KLEIN; Nicolas Duverger; J J Albers; S Marcovina; H Bryan Brewer; Silvia Santamarina-Fojo
In vitro expression of structural defects in the lecithin-cholesterol acyltransferase gene.
The Journal of biological chemistry 1995;270(16):9443-7.
1994: L Previato; O Guardamagna; KA Dugi; R Ronan; GD Talley; Silvia Santamarina-Fojo; H Bryan Brewer
A novel missense mutation in the C-terminal domain of lipoprotein lipase (Glu410-->Val) leads to enzyme inactivation and familial chylomicronemia.
Journal of lipid research 1994;35(9):1552-60.
1994: Silvia Santamarina-Fojo; KA Dugi
Structure, function and role of lipoprotein lipase in lipoprotein metabolism.
Current opinion in lipidology 1994;5(2):117-25.
1994: Silvia Santamarina-Fojo; H Bryan Brewer
Lipoprotein lipase: structure, function and mechanism of action.
International journal of clinical & laboratory research 1994;24(3):143-7.
1993: J Emmerich; Bruno Vergès; Igor Tauveron; Daniel J Rader; Silvia Santamarina-Fojo; J Shaefer; M Ayrault-Jarrier; P Thiéblot; H Bryan Brewer
Familial HDL deficiency due to marked hypercatabolism of normal apoA-I.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(9):1299-306.
1993: H L Dichek; C Parrott; R Ronan; J D Brunzell; H Bryan Brewer; Silvia Santamarina-Fojo
Functional characterization of a chimeric lipase genetically engineered from human lipoprotein lipase and human hepatic lipase.
Journal of lipid research 1993;34(8):1393-40.
1993: HARVEY KLEIN; Silvia Santamarina-Fojo; Nicolas Duverger; M Clerc; M F Dumon; J J Albers; S Marcovina; H Bryan Brewer
Fish eye syndrome: a molecular defect in the lecithin-cholesterol acyltransferase (LCAT) gene associated with normal alpha-LCAT-specific activity. Implications for classification and prognosis.
The Journal of clinical investigation 1993;92(1):479-85.
1993: HARVEY KLEIN; P Lohse; Nicolas Duverger; J J Albers; Daniel J Rader; Loren A Zech; Silvia Santamarina-Fojo; H Bryan Brewer
Two different allelic mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in classic LCAT deficiency: LCAT (tyr83-->stop) and LCAT (tyr156-->asn).
Journal of lipid research 1993;34(1):49-58.
1992: KA Dugi; H L Dichek; GD Talley; H Bryan Brewer; Silvia Santamarina-Fojo
Human lipoprotein lipase: the loop covering the catalytic site is essential for interaction with lipid substrates.
The Journal of biological chemistry 1992;267(35):25086-91.
1992: C L Parrott; N Alsayed; R Rebourcet; Silvia Santamarina-Fojo
ApoC-IIParis2: a premature termination mutation in the signal peptide of apoC-II resulting in the familial chylomicronemia syndrome.
Journal of lipid research 1992;33(3):361-7.
1992: J Emmerich; O U Beg; J Peterson; L Previato; J D Brunzell; H Bryan Brewer; Silvia Santamarina-Fojo
Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241.
The Journal of biological chemistry 1992;267(6):4161-5.
1991: L Previato; C L Parrott; Silvia Santamarina-Fojo; H Bryan Brewer
Transcriptional regulation of the human lipoprotein lipase gene in 3T3-L1 adipocytes.
The Journal of biological chemistry 1991;266(28):18958-63.
1991: Silvia Santamarina-Fojo; H Bryan Brewer
The familial hyperchylomicronemia syndrome. New insights into underlying genetic defects.
JAMA : the journal of the American Medical Association 1991;265(7):904-8.