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Angela Santoni
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Research Profile (preview)
Anatomy
Physiology
Living Beings
Chemicals & Drugs
Phenomena
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Network (preview)
64
Frati, Luigi
52
Piccoli, Mario
33
Gismondi, Angela
25
Morrone, Stefania
22
Cifone, Maria Grazia
21
Palmieri, Gabriella
17
Paolini, Rossella
15
Zingoni, Alessandra
14
Testi, Roberto
13
Mainiero, Fabrizio
12
Cippitelli, Marco
12
Galandrini, Ricciarda
10
Eusebi, Fabrizio
9
De Maria, Ruggero
9
Bernardini, Giovanni
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All Publications
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2009: Fionda Cinzia; Soriani Alessandra; Malgarini Giulia; Iannitto Maria Luisa; Santoni Angela; Cippitelli Marco
Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4385-94.
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2009: Soriani Alessandra; Zingoni Alessandra; Cerboni Cristina; Iannitto Maria Luisa; Ricciardi Maria Rosaria; Di Gialleonardo Valentina; Cippitelli Marco; Fionda Cinzia; Petrucci Maria Teresa; Guarini Anna; Foà Robin; Santoni Angela
ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype.
Blood 2009;113(15):3503-11.
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2009: Cerboni Cristina; Ardolino Michele; Santoni Angela; Zingoni Alessandra
Detuning CD8+ T lymphocytes by down-regulation of the activating receptor NKG2D: role of NKG2D ligands released by activated T cells.
Blood 2009;113(13):2955-64.
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2009: Molfetta Rosa; Gasparrini Francesca; Peruzzi Giovanna; Vian Laura; Piccoli Mario; Frati Luigi; Santoni Angela; Paolini Rossella
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors.
PloS one 2009;4(5):e5604.
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2008: Parretta Elisabetta; Cassese Giuliana; Santoni Angela; Guardiola John; Vecchio Antonia; Di Rosa Francesca
Kinetics of in vivo proliferation and death of memory and naive CD8 T cells: parameter estimation based on 5-bromo-2'-deoxyuridine incorporation in spleen, lymph nodes, and bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7230-9.
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2008: Santoni Angela; Carlino Claudia; Stabile Helena; Gismondi Angela
Mechanisms underlying recruitment and accumulation of decidual NK cells in uterus during pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989) 2008;59(5):417-24.
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2008: Galandrini Ricciarda; Porpora Maria Grazia; Stoppacciaro Antonella; Micucci Federica; Capuano Cristina; Tassi Ilaria; Di Felice Alessia; Benedetti-Panici Pierluigi; Santoni Angela
Increased frequency of human leukocyte antigen-E inhibitory receptor CD94/NKG2A-expressing peritoneal natural killer cells in patients with endometriosis.
Fertility and sterility 2008;89(5 Suppl):1490-6.
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2008: Bernardini Giovanni; Sciumè Giuseppe; Bosisio Daniela; Morrone Stefania; Sozzani Silvano; Santoni Angela
CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets.
Blood 2008;111(7):3626-34.
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2008: Micucci Federica; Capuano Cristina; Marchetti Enzo; Piccoli Mario; Frati Luigi; Santoni Angela; Galandrini Ricciarda
PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway.
Blood 2008;111(8):4165-72.
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2008: Sartorius Rossella; Pisu Paola; D'Apice Luciana; Pizzella Luciano; Romano Chiara; Cortese Giancarlo; Giorgini Angela; Santoni Angela; Velotti Francesca; De Berardinis Piergiuseppe
The use of filamentous bacteriophage fd to deliver MAGE-A10 or MAGE-A3 HLA-A2-restricted peptides and to induce strong antitumor CTL responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):3719-28.
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2008: Carlino Claudia; Stabile Helena; Morrone Stefania; Bulla Roberta; Soriani Alessandra; Agostinis Chiara; Bossi Fleur; Mocci Carlo; Sarazani Filippo; Tedesco Francesco; Santoni Angela; Gismondi Angela
Recruitment of circulating NK cells through decidual tissues: a possible mechanism controlling NK cell accumulation in the uterus during early pregnancy.
Blood 2008;111(6):3108-15.
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2008: Santoni Angela; Carlino Claudia; Gismondi Angela
Uterine NK cell development, migration and function.
Reproductive biomedicine online 2008;16(2):202-10.
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2007: Fionda Cinzia; Nappi Filomena; Piccoli Mario; Frati Luigi; Santoni Angela; Cippitelli Marco
Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes.
Molecular pharmacology 2007;72(5):1246-57.
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2007: Santoni Angela; Zingoni Alessandra; Cerboni Cristina; Gismondi Angela
Natural killer (NK) cells from killers to regulators: distinct features between peripheral blood and decidual NK cells.
American journal of reproductive immunology (New York, N.Y. : 1989) 2007;58(3):280-8.
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2007: Cassese Giuliana; Parretta Elisabetta; Pisapia Laura; Santoni Angela; Guardiola John; Di Rosa Francesca
Bone marrow CD8 cells down-modulate membrane IL-7Ralpha expression and exhibit increased STAT-5 and p38 MAPK phosphorylation in the organ environment.
Blood 2007;110(6):1960-9.
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2007: Peruzzi Giovanna; Molfetta Rosa; Gasparrini Francesca; Vian Laura; Morrone Stefania; Piccoli Mario; Frati Luigi; Santoni Angela; Paolini Rossella
The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2089-96.
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2007: Molfetta Rosa; Peruzzi Giovanna; Santoni Angela; Paolini Rossella
Negative signals from FcepsilonRI engagement attenuate mast cell functions.
Archivum immunologiae et therapiae experimentalis 2007;55(4):219-29.
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2007: Cerboni Cristina; Zingoni Alessandra; Cippitelli Marco; Piccoli Mario; Frati Luigi; Santoni Angela
Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis.
Blood 2007;110(2):606-15.
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2007: Fionda Cinzia; Nappi Filomena; Piccoli Mario; Frati Luigi; Santoni Angela; Cippitelli Marco
15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4039-50.
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2007: Cerboni Cristina; Neri Francesca; Casartelli Nicoletta; Zingoni Alessandra; Cosman David; Rossi Paolo; Santoni Angela; Doria Margherita
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity.
The Journal of general virology 2007;88(Pt 1):242-50.
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2007: Bürkle Alexander; Caselli Graziella; Franceschi Claudio; Mariani Erminia; Sansoni Paolo; Santoni Angela; Vecchio Giancarlo; Witkowski Jacek M; Caruso Calogero
Pathophysiology of ageing, longevity and age related diseases.
Immunity & ageing : I & A 2007;4():4.
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2006: Micucci Federica; Zingoni Alessandra; Piccoli Mario; Frati Luigi; Santoni Angela; Galandrini Ricciarda
High-efficient lentiviral vector-mediated gene transfer into primary human NK cells.
Experimental hematology 2006;34(10):1344-52.
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2006: Christiansen Dale; Mouhtouris Effie; Milland Julie; Zingoni Alessandra; Santoni Angela; Sandrin Mauro S
Recognition of a carbohydrate xenoepitope by human NKRP1A (CD161).
Xenotransplantation 2006;13(5):440-6.
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2006: Di Bona Danilo; Cippitelli Marco; Fionda Cinzia; Cammà Calogero; Licata Anna; Santoni Angela; Craxì Antonio
Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway.
Journal of hepatology 2006;45(2):271-9.
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2005: Molfetta Rosa; Belleudi Francesca; Peruzzi Giovanna; Morrone Stefania; Leone Laura; Dikic Ivan; Piccoli Mario; Frati Luigi; Torrisi Maria Rosaria; Santoni Angela; Paolini Rossella
CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: a new molecular mechanism to dampen mast cell function.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4208-16.
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2005: Bernardini Giovanni; Kim Ji Yun; Gismondi Angela; Butcher Eugene C; Santoni Angela
Chemoattractant induces LFA-1 associated PI 3K activity and cell migration that are dependent on Fyn signaling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1305-7.
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2005: Galandrini Ricciarda; Micucci Federica; Tassi Ilaria; Cifone Maria Grazia; Cinque Benedetta; Piccoli Mario; Frati Luigi; Santoni Angela
Arf6: a new player in FcgammaRIIIA lymphocyte-mediated cytotoxicity.
Blood 2005;106(2):577-83.
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2005: Parretta Elisabetta; Cassese Giuliana; Barba Pasquale; Santoni Angela; Guardiola John; Di Rosa Francesca
CD8 cell division maintaining cytotoxic memory occurs predominantly in the bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7654-64.
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2005: Zingoni Alessandra; Sornasse Thierry; Cocks Benjamin G; Tanaka Yuetsu; Santoni Angela; Lanier Lewis L
NK cell regulation of T cell-mediated responses.
Molecular immunology 2005;42(4):451-4.
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2005: Cippitelli Marco; Fionda Cinzia; Di Bona Danilo; Piccoli Mario; Frati Luigi; Santoni Angela
Hyperthermia enhances CD95-ligand gene expression in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):223-32.
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2004: Pisegna Simona; Pirozzi Gianluca; Piccoli Mario; Frati Luigi; Santoni Angela; Palmieri Gabriella
p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells.
Blood 2004;104(13):4157-64.
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2004: Zingoni Alessandra; Sornasse Thierry; Cocks Benjamin G; Tanaka Yuetsu; Santoni Angela; Lanier Lewis L
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3716-24.
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2004: Bertini Riccardo; Allegretti Marcello; Bizzarri Cinzia; Moriconi Alessio; Locati Massimo; Zampella Giuseppe; Cervellera Maria N; Di Cioccio Vito; Cesta Maria C; Galliera Emanuela; Martinez Fernando O; Di Bitondo Rosa; Troiani Giulia; Sabbatini Vilma; D'Anniballe Gaetano; Anacardio Roberto; Cutrin Juan C; Cavalieri Barbara; Mainiero Fabrizio; Strippoli Raffaele; Villa Pia; Di Girolamo Maria; Martin Franck; Gentile Marco; Santoni Angela; Corda Daniela; Poli Giuseppe; Mantovani Alberto; Ghezzi Pietro; Colotta Francesco
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11791-6.
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2004: Gismondi Angela; Cifaldi Loredana; Mazza Cinzia; Giliani Silvia; Parolini Silvia; Morrone Stefania; Jacobelli Jordan; Bandiera Elisabetta; Notarangelo Luigi; Santoni Angela
Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect.
Blood 2004;104(2):436-43.
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2004: Di Cioccio Vito; Strippoli Raffaele; Bizzarri Cinzia; Troiani Giulia; Cervellera Maria Neve; Gloaguen Isabelle; Colagrande Antonella; Cattozzo Elisa Margherita; Pagliei Sabrina; Santoni Angela; Colotta Francesco; Mainiero Fabrizio; Bertini Riccardo
Key role of proline-rich tyrosine kinase 2 in interleukin-8 (CXCL8/IL-8)-mediated human neutrophil chemotaxis.
Immunology 2004;111(4):407-15.
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2004: Bernardini Giovanni; Ribatti Domenico; Spinetti Gaia; Morbidelli Lucia; Ziche Marina; Santoni Angela; Capogrossi Maurizio C; Napolitano Monica
In vitro and in vivo models to study chemokine regulation of angiogenesis.
Methods in molecular biology (Clifton, N.J.) 2004;239():223-32.
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2004: Gismondi Angela; Mainiero Fabrizio; Santoni Angela
Evaluation of Rho family small G-protein activity induced by integrin ligation on human leukocytes.
Methods in molecular biology (Clifton, N.J.) 2004;239():69-76.
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2003: Cippitelli Marco; Fionda Cinzia; Di Bona Danilo; Lupo Aldo; Piccoli Mario; Frati Luigi; Santoni Angela
The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4578-92.
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2003: Gismondi Angela; Jacobelli Jordan; Strippoli Raffaele; Mainiero Fabrizio; Soriani Alessandra; Cifaldi Loredana; Piccoli Mario; Frati Luigi; Santoni Angela
Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3065-73.
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2003: Di Rosa Francesca; Santoni Angela
Memory T-cell competition for bone marrow seeding.
Immunology 2003;108(3):296-304.
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2003: Sartorius Rossella; D'Apice Luciana; Barba Pasquale; Guardiola John; Santoni Angela; Velotti Francesca; De Berardinis Piergiuseppe
Induction of human NK cell-mediated cytotoxicity by CD40 triggering on antigen presenting cells.
Cellular immunology 2003;221(2):81-8.
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2003: Bernardini Giovanni; Ribatti Domenico; Spinetti Gaia; Morbidelli Lucia; Ziche Marina; Santoni Angela; Capogrossi Maurizio C; Napolitano Monica
Analysis of the role of chemokines in angiogenesis.
Journal of immunological methods 2003;273(1-2):83-101.
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2003: Torelli Giovanni F; Paolini Rossella; Tatarelli Caterina; Soriani Alessandra; Vitale Antonella; Guarini Anna; Santoni Angela; Foa Robin
Defective expression of the T-cell receptor-CD3 zeta chain in T-cell acute lymphoblastic leukaemia.
British journal of haematology 2003;120(2):201-8.
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2003: Spinetti Gaia; Bernardini Giovanni; Camarda Grazia; Mangoni Antonella; Santoni Angela; Capogrossi Maurizio C; Napolitano Monica
The chemokine receptor CCR8 mediates rescue from dexamethasone-induced apoptosis via an ERK-dependent pathway.
Journal of leukocyte biology 2003;73(1):201-7.
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2002: Galandrini Ricciarda; Tassi Ilaria; Mattia Gianfranco; Lenti Luisa; Piccoli Mario; Frati Luigi; Santoni Angela
SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells.
Blood 2002;100(13):4581-9.
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2002: Paolini Rossella; Molfetta Rosa; Beitz Laurie O; Zhang Juan; Scharenberg Andrew M; Piccoli Mario; Frati Luigi; Siraganian Reuben; Santoni Angela
Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.
The Journal of biological chemistry 2002;277(40):36940-7.
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2002: Di Rosa Francesca; Santoni Angela
Bone marrow CD8 T cells are in a different activation state than those in lymphoid periphery.
European journal of immunology 2002;32(7):1873-80.
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2002: Pisegna Simona; Zingoni Alessandra; Pirozzi Gianluca; Cinque Benedetta; Cifone Maria Grazia; Morrone Stefania; Piccoli Mario; Frati Luigi; Palmieri Gabriella; Santoni Angela
Src-dependent Syk activation controls CD69-mediated signaling and function on human NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):68-74.
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2002: Limatola C; Ciotti M T; Mercanti D; Santoni A; Eusebi F
Signaling pathways activated by chemokine receptor CXCR2 and AMPA-type glutamate receptors and involvement in granule cells survival.
Journal of neuroimmunology 2002;123(1-2):9-17.
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2002: Torelli Giovanni F; Guarini Anna; Palmieri Gabriella; Breccia Massimo; Vitale Antonella; Santoni Angela; Foa Robin
Expansion of cytotoxic effectors with lytic activity against autologous blasts from acute myeloid leukaemia patients in complete haematological remission.
British journal of haematology 2002;116(2):299-307.
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2002: Cippitelli Marco; Fionda Cinzia; Di Bona Danilo; Di Rosa Francesca; Lupo Aldo; Piccoli Mario; Frati Luigi; Santoni Angela
Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1154-66.
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2001: Paolini R; Molfetta R; Piccoli M; Frati L; Santoni A
Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9611-6.
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2001: Galandrini R; Tassi I; Morrone S; Lanfrancone L; Pelicci P; Piccoli M; Frati L; Santoni A
The adaptor protein shc is involved in the negative regulation of NK cell-mediated cytotoxicity.
European journal of immunology 2001;31(7):2016-25.
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2000: Bernardini G; Spinetti G; Ribatti D; Camarda G; Morbidelli L; Ziche M; Santoni A; Capogrossi M C; Napolitano M
I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo.
Blood 2000;96(13):4039-45.
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2000: Mainiero F; Gismondi A; Strippoli R; Jacobelli J; Soriani A; Morrone S; Santoni A
Integrin-mediated regulation of cytokine and chemokine production by human natural killer cells.
European cytokine network 2000;11(3):493-4.
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2000: Limatola C; Giovannelli A; Maggi L; Ragozzino D; Castellani L; Ciotti M T; Vacca F; Mercanti D; Santoni A; Eusebi F
SDF-1alpha-mediated modulation of synaptic transmission in rat cerebellum.
The European journal of neuroscience 2000;12(7):2497-504.
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2000: Limatola C; Ciotti M T; Mercanti D; Vacca F; Ragozzino D; Giovannelli A; Santoni A; Eusebi F; Miledi R
The chemokine growth-related gene product beta protects rat cerebellar granule cells from apoptotic cell death through alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6197-201.
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2000: Ricca A; Biroccio A; Del Bufalo D; Mackay A R; Santoni A; Cippitelli M
bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells.
International journal of cancer. Journal international du cancer 2000;86(2):188-96.
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2000: Gismondi A; Jacobelli J; Mainiero F; Paolini R; Piccoli M; Frati L; Santoni A
Cutting edge: functional role for proline-rich tyrosine kinase 2 in NK cell-mediated natural cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2272-6.
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2000: Zingoni A; Palmieri G; Morrone S; Carretero M; Lopez-Botel M; Piccoli M; Frati L; Santoni A
CD69-triggered ERK activation and functions are negatively regulated by CD94 / NKG2-A inhibitory receptor.
European journal of immunology 2000;30(2):644-51.
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2000: Mainiero F; Soriani A; Strippoli R; Jacobelli J; Gismondi A; Piccoli M; Frati L; Santoni A
RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells.
Immunity 2000;12(1):7-16.
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1999: Limatola C; Mileo A M; Giovannelli A; Vacca F; Ciotti M T; Mercanti D; Santoni A; Eusebi F
The growth-related gene product beta induces sphingomyelin hydrolysis and activation of c-Jun N-terminal kinase in rat cerebellar granule neurones.
The Journal of biological chemistry 1999;274(51):36537-43.
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1999: Napolitano M; Santoni A
Structure and function of the CC chemokine receptor (CCR) 8.
Forum (Genoa, Italy) 1999;9(4):315-24.
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1999: Paolini R; Serra A; Molfetta R; Piccoli M; Frati L; Santoni A
Tyrosine kinase-dependent ubiquitination of CD16 zeta subunit in human NK cells following receptor engagement.
European journal of immunology 1999;29(10):3179-87.
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1999: Palmieri G; Tullio V; Zingoni A; Piccoli M; Frati L; Lopez-Botet M; Santoni A
CD94/NKG2-A inhibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7181-8.
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1999: Cifone M G; D'Alò S; Parroni R; Millimaggi D; Biordi L; Martinotti S; Santoni A
Interleukin-2-activated rat natural killer cells express inducible nitric oxide synthase that contributes to cytotoxic function and interferon-gamma production.
Blood 1999;93(11):3876-84.
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1999: Cifone M G; Migliorati G; Parroni R; Marchetti C; Millimaggi D; Santoni A; Riccardi C
Dexamethasone-induced thymocyte apoptosis: apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases.
Blood 1999;93(7):2282-96.
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1999: Galandrini R; Palmieri G; Piccoli M; Frati L; Santoni A
Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK cell cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3148-52.
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1999: Milella M; Jacobelli J; Cavallo F; Guarini A; Velotti F; Frati L; Foà R; Forni G; Santoni A
Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder.
British journal of cancer 1999;79(5-6):770-9.
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1999: Milella M; Gismondi A; Roncaioli P; Palmieri G; Morrone S; Piccoli M; Frati L; Cifone M G; Santoni A
Beta 1 integrin cross-linking inhibits CD16-induced phospholipase D and secretory phospholipase A2 activity and granule exocytosis in human NK cells: role of phospholipase D in CD16-triggered degranulation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2064-72.
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1999: Gismondi A; Santoni A
Integrin-mediated stimulation of tyrosine phosphorylation in lymphoid cells.
Methods in molecular biology (Clifton, N.J.) 1999;96():205-10.
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1999: De Maria R; Palmieri G; Santoni A
Induction of Ca2+ flux by adhesion molecules in lymphocytes.
Methods in molecular biology (Clifton, N.J.) 1999;96():199-204.
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1998: Giovannelli A; Limatola C; Ragozzino D; Mileo A M; Ruggieri A; Ciotti M T; Mercanti D; Santoni A; Eusebi F
CXC chemokines interleukin-8 (IL-8) and growth-related gene product alpha (GROalpha) modulate Purkinje neuron activity in mouse cerebellum.
Journal of neuroimmunology 1998;92(1-2):122-32.
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1998: Sozzani S; Luini W; Bianchi G; Allavena P; Wells T N; Napolitano M; Bernardini G; Vecchi A; D'Ambrosio D; Mazzeo D; Sinigaglia F; Santoni A; Maggi E; Romagnani S; Mantovani A
The viral chemokine macrophage inflammatory protein-II is a selective Th2 chemoattractant.
Blood 1998;92(11):4036-9.
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1998: Ragozzino D; Giovannelli A; Mileo A M; Limatola C; Santoni A; Eusebi F
Modulation of the neurotransmitter release in rat cerebellar neurons by GRO beta.
Neuroreport 1998;9(16):3601-6.
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1998: De Vita L; Accapezzato D; Mangino G; Morrone S; Santilio I; Casciaro M A; Fava D; Bruno G; Del Prete G; Santoni A; Barnaba V
Defective Th1 and Th2 cytokine synthesis in the T-T cell presentation model for lack of CD40/CD40 ligand interaction.
European journal of immunology 1998;28(11):3552-63.
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1998: Cippitelli M; Santoni A
Vitamin D3: a transcriptional modulator of the interferon-gamma gene.
European journal of immunology 1998;28(10):3017-30.
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1998: Mainiero F; Gismondi A; Soriani A; Cippitelli M; Palmieri G; Jacobelli J; Piccoli M; Frati L; Santoni A
Integrin-mediated ras-extracellular regulated kinase (ERK) signaling regulates interferon gamma production in human natural killer cells.
The Journal of experimental medicine 1998;188(7):1267-75.
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1998: Zingoni A; Soto H; Hedrick J A; Stoppacciaro A; Storlazzi C T; Sinigaglia F; D'Ambrosio D; O'Garra A; Robinson D; Rocchi M; Santoni A; Zlotnik A; Napolitano M
The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):547-51.
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1998: Cerboni C; Gismondi A; Palmieri G; Piccoli M; Frati L; Santoni A
CD16-mediated activation of phosphatidylinositol-3 kinase (PI-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc, pp36 and p85 PI-3K subunit.
European journal of immunology 1998;28(3):1005-15.
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1998: Bernardini G; Hedrick J; Sozzani S; Luini W; Spinetti G; Weiss M; Menon S; Zlotnik A; Mantovani A; Santoni A; Napolitano M
Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor.
European journal of immunology 1998;28(2):582-8.
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1997: Gismondi A; Bisogno L; Mainiero F; Palmieri G; Piccoli M; Frati L; Santoni A
Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):4729-36.
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1997: Galandrini R; Palmieri G; Paolini R; Piccoli M; Frati L; Santoni A
Selective binding of shc-SH2 domain to tyrosine-phosphorylated zeta but not gamma-chain upon CD16 ligation on human NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(8):3767-73.
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1997: Nista A; Leonetti C; Bernardini G; Mattioni M; Santoni A
Functional role of alpha4beta1 and alpha5beta1 integrin fibronectin receptors expressed on adriamycin-resistant MCF-7 human mammary carcinoma cells.
International journal of cancer. Journal international du cancer 1997;72(1):133-41.
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1997: Grazia Cifone M; Roncaioli P; Cironi L; Festuccia C; Meccia A; D'Aló S; Botti D; Santoni A
NKR-P1A stimulation of arachidonate-generating enzymes in rat NK cells is associated with granule release and cytotoxic activity.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):309-17.
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1997: Zingoni A; Rocchi M; Storlazzi C T; Bernardini G; Santoni A; Napolitano M
Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor.
Genomics 1997;42(3):519-23.
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1997: Milella M; Gismondi A; Roncaioli P; Bisogno L; Palmieri G; Frati L; Cifone M G; Santoni A
CD16 cross-linking induces both secretory and extracellular signal-regulated kinase (ERK)-dependent cytosolic phospholipase A2 (PLA2) activity in human natural killer cells: involvement of ERK, but not PLA2, in CD16-triggered granule exocytosis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3148-54.
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1997: Palmieri G; Santoni A
NK receptors and signalling.
Research in immunology 1997;148(3):184-90.
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1997: Santoni A; Velotti F; Giuffrida A; Santoni G; Piccoli M
Locoregional IL-2 immunotherapy of bladder cancer.
Immunopharmacology and immunotoxicology 1997;19(1):1-13.
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1997: Limatola C; Barabino B; Nista A; Santoni A
Interleukin 1-beta-induced protein kinase C-zeta activation is mimicked by exogenous phospholipase D.
The Biochemical journal 1997;321 ( Pt 2)():497-501.
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1996: Galandrini R; Piccoli M; Frati L; Santoni A
Tyrosine kinase-dependent activation of human NK cell functions upon triggering through CD44 receptor.
European journal of immunology 1996;26(12):2807-11.
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1996: Napolitano M; Zingoni A; Bernardini G; Spinetti G; Nista A; Storlazzi C T; Rocchi M; Santoni A
Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(7):2759-63.
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1996: Cifone M G; Cironi L; Roncaioli P; Martinotti S; Toniato E; Cilenti L; Botti D; Solito R; Parente L; Santoni A
Phospholipase A2 activity and calpactin I levels in rat lymphokine-activated killer cells: correlation with the cytotoxic activity.
Cellular immunology 1996;170(2):274-82.
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1996: Fanciulli M; Bruno T; Cerboni C; Bonetto F; Iacobini C; Frati L; Piccoli M; Floridi A; Santoni A; Punturieri A
Cloning of a novel human RNA polymerase II subunit downregulated by doxorubicin: new potential mechanisms of drug related toxicity.
FEBS letters 1996;384(1):48-52.
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1996: Nista A; Mattioni M; Gismondi A; Palmieri G; Santoni A
beta 1-Integrin expression and function in human bladder cancer cells: modulation by TNF alpha.
Anticancer research 1996;16(2):581-8.
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1996: De Maria R; Boirivant M; Cifone M G; Roncaioli P; Hahne M; Tschopp J; Pallone F; Santoni A; Testi R
Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation.
The Journal of clinical investigation 1996;97(2):316-22.
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1996: Galandrini R; Palmieri G; Piccoli M; Frati L; Santoni A
CD16-mediated p21ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells.
The Journal of experimental medicine 1996;183(1):179-86.
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1996: Palmieri G; Gismondi A; Galandrini R; Milella M; Serra A; De Maria R; Santoni A
Interaction of natural killer cells with extracellular matrix induces early intracellular signalling events and enhances cytotoxic functions.
Natural immunity 1996;15(2-3):147-53.
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1995: Cifone M G; Roncaioli P; De Maria R; Camarda G; Santoni A; Ruberti G; Testi R
Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.
The EMBO journal 1995;14(23):5859-68.
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1995: Tubaro E; Borelli G P; Belogi L; Cavallo G; Santoni A; Mainiero F
Effect of a new de-N-acetyl-lysoglycosphingolipid on some tumour models.
European journal of pharmacology 1995;294(2-3):555-63.
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1995: Palmieri G; Serra A; De Maria R; Gismondi A; Milella M; Piccoli M; Frati L; Santoni A
Cross-linking of alpha 4 beta 1 and alpha 5 beta 1 fibronectin receptors enhances natural killer cell cytotoxic activity.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5314-22.
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1995: Testi R; Cifone M G; Santoni A
Role of CD69 in NO production by human monocytes.
Research in immunology 1995;146(9):682-3.
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1995: Cifone M G; Cironi L; Santoni A; Testi R
Diacylglycerol lipase activation and 5-lipoxygenase activation and translocation following TCR/CD3 triggering in T cells.
European journal of immunology 1995;25(4):1080-6.
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1995: Gismondi A; Milella M; Palmieri G; Piccoli M; Frati L; Santoni A
Stimulation of protein tyrosine phosphorylation by interaction of NK cells with fibronectin via alpha 4 beta 1 and alpha 5 beta 1.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3128-37.
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1995: Cifone M G; Cironi L; Meccia M A; Roncaioli P; Festuccia C; De Nuntiis G; D'Aló S; Santoni A
Role of nitric oxide in cell-mediated tumor cytotoxicity.
Advances in neuroimmunology 1995;5(4):443-61.
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1995: Tubaro A; Stoppacciaro A; Velotti F; Bossola P C; Cusumano G; Vicentini C; De Carli P; Ruco L; Santoni A; Cancrini A
Local immunotherapy of superficial bladder cancer by intravesical instillation of recombinant interleukin-2.
European urology 1995;28(4):297-303.
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1994: De Maria R; Cifone M G; Trotta R; Rippo M R; Festuccia C; Santoni A; Testi R
Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors.
The Journal of experimental medicine 1994;180(5):1999-2004.
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1994: Santoni G; Gismondi A; Liu J H; Punturieri A; Santoni A; Frati L; Piccoli M; Djeu J Y
Candida albicans expresses a fibronectin receptor antigenically related to alpha 5 beta 1 integrin.
Microbiology (Reading, England) 1994;140 ( Pt 11)():2971-9.
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1994: Galandrini R; De Maria R; Piccoli M; Frati L; Santoni A
CD44 triggering enhances human NK cell cytotoxic functions.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(10):4399-407.
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1994: Testi R; D'Ambrosio D; De Maria R; Santoni A
The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells.
Immunology today 1994;15(10):479-83.
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1994: Tubaro E; Croce C; Cavallo G; Belogi L; Guida G; Santiangeli C; Cifone M G; Santoni A; Mainiero F
In vitro and in vivo impact of a new glycosphingolipid on neutrophils.
Agents and actions 1994;42(3-4):107-13.
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1994: Grassi F; Mileo A M; Monaco L; Punturieri A; Santoni A; Eusebi F
TNF-alpha increases the frequency of spontaneous miniature synaptic currents in cultured rat hippocampal neurons.
Brain research 1994;659(1-2):226-30.
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1994: Cifone M G; De Maria R; Roncaioli P; Rippo M R; Azuma M; Lanier L L; Santoni A; Testi R
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.
The Journal of experimental medicine 1994;180(4):1547-52.
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1994: Cifone M G; Festuccia C; Cironi L; Cavallo G; Chessa M A; Pensa V; Tubaro E; Santoni A
Induction of the nitric oxide-synthesizing pathway in fresh and interleukin 2-cultured rat natural killer cells.
Cellular immunology 1994;157(1):181-94.
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1994: Jannini E A; Ulisse S; Cecconi S; Cironi L; Colonna R; D'Armiento M; Santoni A; Cifone M G
Follicle-stimulating hormone-induced phospholipase A2 activity and eicosanoid generation in rat Sertoli cells.
Biology of reproduction 1994;51(1):140-5.
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1994: D'Ambrosio D; Cantrell D A; Frati L; Santoni A; Testi R
Involvement of p21ras activation in T cell CD69 expression.
European journal of immunology 1994;24(3):616-20.
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1994: Mainiero F; Gismondi A; Milella M; Morrone S; Palmieri G; Piccoli M; Frati L; Santoni A
Long term activation of natural killer cells results in modulation of beta 1-integrin expression and function.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):446-54.
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1994: Santoni A; Gismondi A; Mainiero F; Palmieri G; Morrone S; Milella M; Piccoli M; Frati L
Regulation and function of fibronectin receptors expressed by natural killer cells.
Immunology series 1994;61():55-62.
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1993: De Maria R; Fais S; Silvestri M; Frati L; Pallone F; Santoni A; Testi R
Continuous in vivo activation and transient hyporesponsiveness to TcR/CD3 triggering of human gut lamina propria lymphocytes.
European journal of immunology 1993;23(12):3104-8.
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1993: D'Ambrosio D; Trotta R; Vacca A; Frati L; Santoni A; Gulino A; Testi R
Transcriptional regulation of interleukin-2 gene expression by CD69-generated signals.
European journal of immunology 1993;23(11):2993-7.
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1993: Cifone M G; Botti D; Festuccia C; Napolitano T; del Grosso E; Cavallo G; Chessa M A; Santoni A
Involvement of phospholipase A2 activation and arachidonic acid metabolism in the cytotoxic functions of rat NK cells.
Cellular immunology 1993;148(2):247-58.
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1993: Ruco L P; Paradiso P; Pittiglio M; Diodoro M G; Gearing A J; Mainiero F; Gismondi A; Santoni A; Baroni C D
Tissue distribution of very late activation antigens-1/6 and very late activation antigen ligands in the normal thymus and in thymoma.
The American journal of pathology 1993;142(3):765-72.
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1992: Gismondi A; Mainiero F; Morrone S; Palmieri G; Piccoli M; Frati L; Santoni A
Triggering through CD16 or phorbol esters enhances adhesion of NK cells to laminin via very late antigen 6.
The Journal of experimental medicine 1992;176(5):1251-7.
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1992: Tancredi V; D'Arcangelo G; Grassi F; Tarroni P; Palmieri G; Santoni A; Eusebi F
Tumor necrosis factor alters synaptic transmission in rat hippocampal slices.
Neuroscience letters 1992;146(2):176-8.
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1992: Velotti F; Giuffrida A; Cippitelli M; Stoppacciaro A; Tubaro A; Ruco L; Santoni A
Soluble and cell-associated IL-2 receptor (IL-2R) after local immunotherapy with recombinant interleukin-2 (rIL-2).
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():52-3.
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1992: Testi R; Pulcinelli F M; Cifone M G; Botti D; Del Grosso E; Riondino S; Frati L; Gazzaniga P P; Santoni A
Preferential involvement of a phospholipase A2-dependent pathway in CD69-mediated platelet activation.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2867-71.
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1992: Velotti F; Palmieri G; D'Ambrosio D; Piccoli M; Frati L; Santoni A
Differential expression of granzyme A and granzyme B proteases and their secretion by fresh rat natural killer cells (NK) and lymphokine-activated killer cells with NK phenotype (LAK-NK).
European journal of immunology 1992;22(4):1049-53.
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1992: Palmieri G; Morrone S; Lollini P L; De Giovanni C; Nicoletti G; Nanni P; Frati L; Santoni A
TNF impairs in vivo and in vitro natural killer (NK) susceptibility of B16 melanoma cells.
Scandinavian journal of immunology 1992;35(3):279-87.
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1991: D'Arcangelo G; Grassi F; Ragozzino D; Santoni A; Tancredi V; Eusebi F
Interferon inhibits synaptic potentiation in rat hippocampus.
Brain research 1991;564(2):245-8.
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1991: Tubaro A; Velotti F; Stoppacciaro A; Santoni A; Vicentini C; Bossola P C; Galassi P; Pettinato A; Morrone S; Napolitano T
Continuous intra-arterial administration of recombinant interleukin-2 in low-stage bladder cancer. A phase IB study.
Cancer 1991;68(1):56-61.
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1991: Procopio A D; Paolini R; Vecchio I; Frati L; Santoni A
GTP-binding proteins transduce signals generated via human FC gamma receptor IIIA (CD16).
Journal of immunology (Baltimore, Md. : 1950) 1991;146(10):3550-6.
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1991: Screpanti I; Felli M P; Toniato E; Meco D; Martinotti S; Frati L; Santoni A; Gulino A
Enhancement of natural-killer-cell susceptibility of human breast-cancer cells by estradiol and v-Ha-ras oncogene.
International journal of cancer. Journal international du cancer 1991;47(3):445-9.
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1991: Gismondi A; Morrone S; Humphries M J; Piccoli M; Frati L; Santoni A
Human natural killer cells express VLA-4 and VLA-5, which mediate their adhesion to fibronectin.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(1):384-92.
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1991: Piccoli M; Santoni G; Santoni A; Frati L; Herberman R B; Chirigos M A
Inhibition of NK cell generation by Corynebacterium parvum.
Immunopharmacology and immunotoxicology 1991;13(4):513-29.
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1990: Ruco L P; Pomponi D; Pigott R; Stoppacciaro A; Monardo F; Uccini S; Boraschi D; Tagliabue A; Santoni A; Dejana E
Cytokine production (IL-1 alpha, IL-1 beta, and TNF alpha) and endothelial cell activation (ELAM-1 and HLA-DR) in reactive lymphadenitis, Hodgkin's disease, and in non-Hodgkin's lymphomas. An immunocytochemical study.
The American journal of pathology 1990;137(5):1163-71.
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1990: Ruco L P; Pisacane A; Pomponi D; Stoppacciaro A; Pescarmona E; Rendina E A; Santoni A; Boraschi D; Tagliabue A; Uccini S
Macrophages and interdigitating reticulum cells in normal human thymus and thymomas: immunoreactivity for interleukin-1 alpha, interleukin-1 beta and tumour necrosis factor alpha.
Histopathology 1990;17(4):291-9.
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1990: Gulino A; Vacca A; Farina A R; Screpanti I; Maroder M; Gismondi A; Santoni A; Frati L; Luethy J D; Holbrook N J
T-cell restricted and unrestricted expression of transfected human interleukin-2 gene: phorbol ester- and calcium-inducible versus constitutive expression.
Biochimica et biophysica acta 1990;1087(1):7-17.
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1990: Famularo G; Procopio A; Giacomelli R; Danese C; Sacchetti S; Perego M A; Santoni A; Tonietti G
Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis.
Clinical and experimental immunology 1990;81(3):368-72.
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1990: Testi R; Pulcinelli F; Frati L; Gazzaniga P P; Santoni A
CD69 is expressed on platelets and mediates platelet activation and aggregation.
The Journal of experimental medicine 1990;172(3):701-7.
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1990: Cifone M G; Procopio A; Napolitano T; Alesse E; Santoni G; Santoni A
Cadmium inhibits spontaneous (NK), antibody-mediated (ADCC) and IL-2-stimulated cytotoxic functions of natural killer cells.
Immunopharmacology 1990;20(2):73-80.
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1990: Tancredi V; Zona C; Velotti F; Eusebi F; Santoni A
Interleukin-2 suppresses established long-term potentiation and inhibits its induction in the rat hippocampus.
Brain research 1990;525(1):149-51.
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1990: Grazia Cifone M; Giacomelli R; Famularo G; Paolini R; Danese C; Napolitano T; Procopio A; Perego A M; Santoni A; Tonietti G
Natural killer activity and antibody-dependent cellular cytotoxicity in progressive systemic sclerosis.
Clinical and experimental immunology 1990;80(3):360-5.
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1990: Vacca A; Martinotti S; Screpanti I; Maroder M; Felli M P; Farina A R; Gismondi A; Santoni A; Frati L; Gulino A
Transcriptional regulation of the interleukin 2 gene by glucocorticoid hormones. Role of steroid receptor and antigen-responsive 5'-flanking sequences.
The Journal of biological chemistry 1990;265(14):8075-80.
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1990: Santoni A; Santoni G; Piccoli M; Herberman R B; Frati L
Characterization of Corynebacterium parvum-induced suppressor cells of mouse NK and ADCC activity.
Immunopharmacology and immunotoxicology 1990;12(3):363-87.
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1990: Giuffrida A; Galli M C; Gismondi A; Santoni G; Piccoli M; Cavallo G; Tubaro E; Frati L; Santoni A
Augmentation of mouse natural killer (NK) activity by GM-1/P, a processed form of monosialoganglioside GM-1.
Immunopharmacology and immunotoxicology 1990;12(4):545-63.
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1989: Ruco L P; Stoppacciaro A; Pomponi D; Boraschi D; Santoni A; Tagliabue A; Uccini S; Baroni C D
Immunoreactivity for IL-1 beta and TNF alpha in human lymphoid and nonlymphoid tissues.
The American journal of pathology 1989;135(5):889-97.
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1989: Cifone M G; Alesse E; Di Eugenio R; Napolitano T; Morrone S; Paolini R; Santoni G; Santoni A
In vivo cadmium treatment alters natural killer activity and large granular lymphocyte number in the rat.
Immunopharmacology 1989;18(3):149-56.
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1989: Punturieri A; Santoni A; Ming W J; Nobili N; Mantovani A; Bottazzi B
In vitro migration of rat large granular lymphocytes.
Cellular immunology 1989;123(2):257-63.
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1989: Santoni A; Gismondi A; Morrone S; Procopio A; Modesti A; Scarpa S; D'Orazi G; Piccoli M; Frati L
Rat natural killer cells synthesize fibronectin. Possible involvement in the cytotoxic function.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(7):2415-21.
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1989: Morrone S; Scarpa S; Punturieri A; Testi R; Gismondi A; Santoni G; Piccoli M; Frati L; Modesti A; Santoni A
Laminin synthesis by NK cells and modulation of its expression by TPA (12-O-tetradecanoylphorbol-13-acetate).
Experimental cell research 1989;182(2):543-9.
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1989: Famularo G; Giacomelli R; Alesse E; Cifone M G; Morrone S; Boirivant M; Danese C; Perego M A; Santoni A; Tonietti G
Polyclonal B lymphocyte activation in progressive systemic sclerosis.
Journal of clinical & laboratory immunology 1989;29(2):59-63.
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1989: Screpanti I; Morrone S; Meco D; Santoni A; Gulino A; Paolini R; Crisanti A; Mathieson B J; Frati L
Steroid sensitivity of thymocyte subpopulations during intrathymic differentiation. Effects of 17 beta-estradiol and dexamethasone on subsets expressing T cell antigen receptor or IL-2 receptor.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(10):3378-83.
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1989: Velotti F; Palmieri G; Morrone S; Piccoli M; Frati L; Santoni A
Granzyme A expression by normal rat natural killer (NK) cells in vivo and by interleukin 2-activated NK cells in vitro.
European journal of immunology 1989;19(3):575-8.
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1989: Grazia Cifone M; Alesse E; Procopio A; Paolini R; Morrone S; Di Eugenio R; Santoni G; Santoni A
Effects of cadmium on lymphocyte activation.
Biochimica et biophysica acta 1989;1011(1):25-32.
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1989: Procopio A D; Paolini R; Gismondi A; Piccoli M; Adamo S; Cavallo G; Frati L; Santoni A
Effects of protein kinase C (PK-C) activators and inhibitors on human large granular lymphocytes (LGL): role of PK-C on natural killer (NK) activity.
Cellular immunology 1989;118(2):470-81.
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1989: Punturieri A; Velotti F; Piccoli M; Herberman R B; Frati L; Santoni A
Overnight incubation of mouse spleen cells in recombinant IL-2 generates cytotoxic cells with NK characteristics from precursors enriched with or devoid of LGL.
Clinical and experimental immunology 1989;75(1):155-60.
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1988: Procopio A; Gismondi A; Paolini R; Morrone S; Testi R; Piccoli M; Frati L; Herberman R B; Santoni A
Proliferative effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) and calcium ionophores on human large granular lymphocytes (LGL).
Cellular immunology 1988;113(1):70-81.
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