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Ferran Sanz

Research Profile

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Chemicals & Drugs

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Spain

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Publications

TOP 3
José Luís Oliveira; Ferran Sanz; Bharat Singh; Erik M Van Mulligen; Ernst Ahlberg; Paul Avillach; Anna Bauer-Mehren; Scott Boyer; David Campos; Maria C Carrascosa; Gayo Diallo; Carlos Díaz Acedo; Laura I Furlong; Jan A Kors; Pedro Lopes; Jordi Mestres; Tiago Nunes; Johan van der Lei
The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.
Anna Bauer-Mehren; Scott Boyer; María Del Carmen Carrascosa; Gayo Diallo; Ernst Ahlberg Helgee; Paul Avillach; Ricard Garcia-Serna; Jan A Kors; Pedro Lopes; Jordi Mestres; José L Oliveira; Janet Piñero; Ferran Sanz; Bharat Singh; Erik M van Mullingen; Laura I Furlong
Automatic filtering and substantiation of drug safety signals.
Cristian Obiol-Pardo; Julio Gomis-Tena; Ferran Sanz; Javier Saiz; Manuel Pastor
A multiscale simulation system for the prediction of drug-induced cardiotoxicity.

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All Publications

2013: José Luís Oliveira; Ferran Sanz; Bharat Singh; Erik M Van Mulligen; Ernst Ahlberg; Paul Avillach; Anna Bauer-Mehren; Scott Boyer; David Campos; Maria C Carrascosa; Gayo Diallo; Carlos Díaz Acedo; Laura I Furlong; Jan A Kors; Pedro Lopes; Jordi Mestres; Tiago Nunes; Johan van der Lei
The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.
Pharmacoepidemiology and drug safety 2013;22(5):459-67.
2012: Anna Bauer-Mehren; Scott Boyer; María Del Carmen Carrascosa; Gayo Diallo; Ernst Ahlberg Helgee; Paul Avillach; Ricard Garcia-Serna; Jan A Kors; Pedro Lopes; Jordi Mestres; José L Oliveira; Janet Piñero; Ferran Sanz; Bharat Singh; Erik M van Mullingen; Laura I Furlong
Automatic filtering and substantiation of drug safety signals.
PLoS computational biology 2012;8(4):e1002457.
2011: Cristian Obiol-Pardo; Julio Gomis-Tena; Ferran Sanz; Javier Saiz; Manuel Pastor
A multiscale simulation system for the prediction of drug-induced cardiotoxicity.
Journal of chemical information and modeling 2011;51(2):483-92.
2011: Anna Bauer-Mehren; Markus Bundschus; Miguel A Mayer; Michael Rautschka; Ferran Sanz; Laura I Furlong
Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases.
PloS one 2011;6(6):e20284.
2010: Anna Bauer-Mehren; Michael Rautschka; Ferran Sanz; Laura I Furlong
DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks.
Bioinformatics (Oxford, England) 2010;26(22):2924-6.
2010: Laura López; Jana Selent; Raquel Ortega; Christian F Masaguer; Eduardo Domínguez; Filipe Areias; José Brea; María Isabel Loza; Ferran Sanz; Manuel Pastor
Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors.
ChemMedChem 2010;5(8):1300-17.
2010: Jana Selent; Anna Bauer-Mehren; Laura López; M Isabel Loza; Ferran Sanz; Manuel Pastor
A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints.
Molecular pharmacology 2010;77(2):149-58.
2010: Jana Selent; Ferran Sanz; Manuel Pastor; Gianni De Fabritiis
Induced effects of sodium ions on dopaminergic G-protein coupled receptors.
PLoS computational biology 2010;6(8):.
2009: Miguel Angel Mayer; Angela Leis; Ferran Sanz
[Health information on the Internet and trust marks as quality indicators: vaccines case study].
Atencion primaria / Sociedad Española de Medicina de Familia y Comunitaria 2009;41(10):534-42.
2009: Marta Pulido; Manresa Josep Maria; Sergi Mojal; Ferran Sanz
[Analysis of knowledge of international criteria for authorship by the Spanish researchers].
Medicina clínica 2009;133(10):381-9.
2009: Raquel Ortega; Enrique Raviña; Christian F Masaguer; Filipe Miguel Areias; José Brea; M Isabel Loza; Laura López; Jana Selent; Manuel Pastor; Ferran Sanz
Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.
Bioorganic & medicinal chemistry letters 2009;19(6):1773-8.
2009: Anna Bauer-Mehren; Laura I Furlong; Michael Rautschka; Ferran Sanz
From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways.
BMC bioinformatics 2009;10 Suppl 8():S6.
2009: Anna Bauer-Mehren; Laura I Furlong; Ferran Sanz
Pathway databases and tools for their exploitation: benefits, current limitations and challenges.
Molecular systems biology 2009;5():290.
2008: Reyes Aranda; Karen Villalba; Enrique Raviña; Christian F Masaguer; José Brea; Filipe Miguel Areias; Eduardo Domínguez; Jana Selent; Laura López; Ferran Sanz; Manuel Pastor; M Isabel Loza
Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics.
Journal of medicinal chemistry 2008;51(19):6085-94.
2008: Martin Hofmann-Apitius; Juliane Fluck; Laura Furlong; Oriol Fornes; Corinna Kolárik; Susanne Hanser; Martin Boeker; Stefan Schulz; Ferran Sanz; Roman Klinger; Theo Mevissen; Tobias Gattermayer; Baldo Oliva; Christoph Friedrich
Knowledge environments representing molecular entities for the virtual physiological human.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2008;366(1878):3091-110.
2008: Jana Selent; Laura López; Ferran Sanz; Manuel Pastor
Multi-receptor binding profile of clozapine and olanzapine: a structural study based on the new beta2 adrenergic receptor template.
ChemMedChem 2008;3(8):1194-8.
2008: Angela Stefanachi; Jose Manuel Brea; María Isabel Cadavid; Nuria B Centeno; Cristina Esteve; M Isabel Loza; Ana Martinez; Rosa Nieto; Enrique Raviña; Ferran Sanz; Victor Segarra; Eddy Sotelo; Bernat Vidal; Angelo Carotti
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
Bioorganic & medicinal chemistry 2008;16(6):2852-69.
2008: Ana Martínez; Hugo Gutierrez de teran; José Brea; Enrique Raviña; M Isabel Loza; María Isabel Cadavid; Ferran Sanz; Bernat Vidal; Victor Segarra; Eddy Sotelo
Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2'-furyl)-1,2,4-triazolo[1,5-a]quinoxalines.
Bioorganic & medicinal chemistry 2008;16(4):2103-13.
2008: Laura I Furlong; Holger Dach; Martin Hofmann-Apitius; Ferran Sanz
OSIRISv1.2: a named entity recognition system for sequence variants of genes in biomedical literature.
BMC bioinformatics 2008;9():84.
2007: Cristina Dezi; José Brea; Mario Alvarado; Enrique Raviña; Christian F Masaguer; M Isabel Loza; Ferran Sanz; Manuel Pastor
Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor.
Journal of medicinal chemistry 2007;50(14):3242-55.
2006: Julio Bonis; Laura Inés Furlong; Ferran Sanz
OSIRIS: a tool for retrieving literature about sequence variants.
Bioinformatics (Oxford, England) 2006;22(20):2567-9.
2006: José Brea; Marian Castro; M Isabel Loza; Christian F Masaguer; Enrique Raviña; Cristina Dezi; Manuel Pastor; Ferran Sanz; Araceli Cabrero-Castel; Beatriz Galán-Rodríguez; Emilio Fernández-Espejo; Rafael Maldonado; Patricia Robledo
QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine.
Neuropharmacology 2006;51(2):251-62.
2006: Angelo Carotti; María Isabel Cadavid; Nuria B Centeno; Cristina Esteve; M Isabel Loza; Ana Martinez; Rosa Nieto; Enrique Raviña; Ferran Sanz; Victor Segarra; Eddy Sotelo; Angela Stefanachi; Bernat Vidal
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
Journal of medicinal chemistry 2006;49(1):282-99.
2005: Esteve Llargués; Carles Díaz; Ramon Fitó; Ferran Sanz
[Assessing the implementation of the VisualCor software in medical practice].
Medicina clínica 2005;124(16):627-9.
2005: Fabien Fontaine; Manuel Pastor; Ismael Zamora; Ferran Sanz
Anchor-GRIND: filling the gap between standard 3D QSAR and the GRid-INdependent descriptors.
Journal of medicinal chemistry 2005;48(7):2687-94.
2004: Montserrat Barbany; Hugo Gutierrez de teran; Ferran Sanz; Jordi Villà-Freixa
Towards a MIP-based alignment and docking in computer-aided drug design.
Proteins 2004;56(3):585-94.
2004: Hugo Gutierrez de teran; Manuel Pastor; Nuria B Centeno; Johan Aqvist; Ferran Sanz
Comparative analysis of putative agonist-binding modes in the human A1 adenosine receptor.
Chembiochem : a European journal of chemical biology 2004;5(6):841-9.
2004: Luis Cordero; María Isabel Cadavid; Fernando Fernandez-Llimos; Carlos Díaz; Ferran Sanz; M Isabel Loza
Continuing education and community pharmacists in Galicia: a study of opinions.
Pharmacy world & science : PWS 2004;26(3):173-7.
2004: Fabien Fontaine; Manuel Pastor; Ferran Sanz
Incorporating molecular shape into the alignment-free Grid-Independent Descriptors.
Journal of medicinal chemistry 2004;47(11):2805-15.
2004: Hugo Gutierrez de teran; Nuria B Centeno; Manuel Pastor; Ferran Sanz
Novel approaches for modeling of the A1 adenosine receptor and its agonist binding site.
Proteins 2004;54(4):705-15.
2003: Montserrat Barbany; Hugo Gutierrez de teran; Ferran Sanz; Jordi Villà-Freixa; Arieh Warshel
On the generation of catalytic antibodies by transition state analogues.
Chembiochem : a European journal of chemical biology 2003;4(4):277-85.
2003: José Brea; Christian F Masaguer; María Villazón; María Isabel Cadavid; Enrique Raviña; Fabien Fontaine; Cristina Dezi; Manuel Pastor; Ferran Sanz; M Isabel Loza
Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT 2A and 5-HT 2C receptor behaviours.
European journal of medicinal chemistry 2003;38(4):433-40.
2003: Fabien Fontaine; Manuel Pastor; Hugo Gutierrez de teran; Juan Jose Lozano ; Ferran Sanz
Use of alignment-free molecular descriptors in diversity analysis and optimal sampling of molecular libraries.
Molecular diversity 2003;6(2):135-47.
2002: Manuel Pastor; Paolo Benedetti; Angelo Carotti; Antonio Carrieri; Carlos Díaz; Cristina Herráiz; Hans-Dieter Höltje; M Isabel Loza; Tudor I Oprea; Fernando Padín; Francesc Pubill; Ferran Sanz; Friederike Stoll
Distant collaboration in drug discovery: the LINK3D project.
Journal of computer-aided molecular design 2002;16(11):809-18.
2002: Ferran Sanz; Federico Gago
Current perspective of information technologies in drug discovery.
Journal of computer-aided molecular design 2002;16(11):767-8.
2002: María-Angeles Honrubia; Jordi Rodrigo; María Isabel Cadavid; José María Calleja; Ferran Sanz; M Isabel Loza
Influence of pH on the binding of diphenylmethylenepiperidines by 5-HT2B receptors in rat stomach fundus.
Chemical & pharmaceutical bulletin 2002;50(3):395-8.
2002: Hugo Gutierrez de teran; Juan Jose Lozano ; V Segarra; Ferran Sanz
Molecular diversity sample generation on the basis of quantum-mechanical computations and principal component analysis.
Combinatorial chemistry & high throughput screening 2002;5(1):49-57.
2002: José Brea; Jordi Rodrigo; Antonio Carrieri; Ferran Sanz; María Isabel Cadavid; María José Enguix; María Villazón; Guadalupe Mengod; Yolanda Caro; Christian F Masaguer; Enrique Raviña; Nuria B Centeno; Angelo Carotti; M Isabel Loza
New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Journal of medicinal chemistry 2002;45(1):54-71.
2002: Orazio Nicolotti; Marialuisa Pellegrini-Calace; C Altomar; Angelo Carotti; Antonio Carrieri; Ferran Sanz
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D quantitative structure-activity relationship (QSAR) Models.
Current medicinal chemistry 2002;9(1):1-29.
2001: Orazio Nicolotti; Marialuisa Pellegrini-Calace; Antonio Carrieri; Cosimo Altomare; Nuria B Centeno; Ferran Sanz; Angelo Carotti
Neuronal nicotinic receptor agonists: a multi-approach development of the pharmacophore.
Journal of computer-aided molecular design 2001;15(9):859-72.
2001: Antonio Carrieri; Nuria B Centeno; J Rodrigo; Ferran Sanz; Angelo Carotti
Theoretical evidence of a salt bridge disruption as the initiating process for the alpha1d-adrenergic receptor activation: a molecular dynamics and docking study.
Proteins 2001;43(4):382-94.
2000: Montserrat Martín-Baranera; Juan Sancho; Ferran Sanz
Controlling for chance agreement in the validation of medical expert systems with no gold standard: PNEUMON-IA and RENOIR revisited.
Computers and biomedical research, an international journal 2000;33(6):380-97.
2000: Ferran Sanz; C Silveira; C Díaz; A Alonso; M Isabel Loza; Luis Cordero; Fernando Fernandez-Llimos; María Isabel Cadavid; L Tiddens; F Giorgio; H Cranz; K Henderson; J Mircheva; J L Fernández
Information technology in community pharmacies for supporting responsible self-medication.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2000;57(17):1601-3.
2000: Juan Jose Lozano ; Manuel Pastor; Gabriele Cruciani; K Gaedt; Nuria B Centeno; F Gago; Ferran Sanz
3D-QSAR methods on the basis of ligand-receptor complexes. Application of COMBINE and GRID/GOLPE methodologies to a series of CYP1A2 ligands.
Journal of computer-aided molecular design 2000;14(4):341-53.
1999: Enrique Raviña; J Negreira; J Cid; Christian F Masaguer; E Rosa; ME Rivas; Jose A Fontenla; M Isabel Loza; Helena Tristán; María Isabel Cadavid; Ferran Sanz; Estrella Lozoya; Angelo Carotti; Antonio Carrieri
Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical antipsychotics.
Journal of medicinal chemistry 1999;42(15):2774-97.
1999: Ferran Sanz; C Silveira; A Alonso; C Diaz; M Isabel Loza; Luis Cordero; Fernando Fernandez-Llimos; L Tiddens; F Giorgio; H Cranz; J Mircheva
Telematics applications to support the role of the community pharmacists as self-medication advisors. TESEMED Consortium.
Studies in health technology and informatics 1999;68():764-7.
1999: M Martin-Baranera; I Planas; J Palau; M Miralles; Juan Sancho; Ferran Sanz
Assessing physician's expectations and attitudes toward hospital information systems. The IMASIS experience.
M.D. computing : computers in medical practice 1999;16(1):73-6.
1998: Juan Sancho; I Planas; D Domènech; Montserrat Martín-Baranera; J Palau; Ferran Sanz
IMASIS. A multicenter hospital information system--experience in Barcelona.
Studies in health technology and informatics 1998;56():35-42.
1998: E Sancho; M R Vilá; L Sánchez-Pulido; Juan Jose Lozano ; Rosanna paciucci; marga nadal; M Fox; C Harvey; B Bercovich; Noureddine Loukili; Aaron Ciechanover; S L Lin; Ferran Sanz; X Estivill; A Valencia; Timothy M Thomson
Role of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells.
Molecular and cellular biology 1998;18(1):576-89.
1997: Juan Jose Lozano ; E López-de-Briñas; Nuria B Centeno; Roderic Guigó; Ferran Sanz
Three-dimensional modelling of human cytochrome P450 1A2 and its interaction with caffeine and MeIQ.
Journal of computer-aided molecular design 1997;11(4):395-408.
1997: María-Angeles Honrubia; J Rodriguez; R Dominguez; Estrella Lozoya; F Manaut; J A Seijas; M C Villaverde; José María Calleja; María Isabel Cadavid; Saul Maayani; Ferran Sanz; M Isabel Loza
Synthesis, affinity at 5-HT2A, 5-HT2B and 5-HT2C serotonin receptors and structure-activity relationships of a series of cyproheptadine analogues.
Chemical & pharmaceutical bulletin 1997;45(5):842-8.
1996: Albert Balaguer; J Argemí; Juan Sancho; A Patak; Ferran Sanz
Newborn Touch: a CAI program in neonatal pathology.
M.D. computing : computers in medical practice 1996;13(4):351-6, 359.
1995: J C González; J Roma-Millán; Juan Sancho; Ferran Sanz
[Informatics in medical schools and postgraduate education centers for health professionals. Survey on the situation in Spain].
Medicina clínica 1995;105(15):570-5.
1995: J C González; M Pulido; Ferran Sanz
[Evaluation of the use of statistical techniques in original articles published in the Medicina Clínica during 3 decades (1962-1992)].
Medicina clínica 1995;104(12):448-52.
1995: R Nogues; Antonio Sitges-Serra; Juan Sancho; Ferran Sanz; J Monne; Meritxell Girvent; J M Gubern
Influence of nutrition, thyroid hormones, and rectal temperature on in-hospital mortality of elderly patients with acute illness.
The American journal of clinical nutrition 1995;61(3):597-602.
1995: M Martín-Baranera; I Planas; J Palau; Ferran Sanz
IMASIS computer-based medical record project: dealing with the human factor.
Medinfo. MEDINFO 1995;8 Pt 1():333.
1994: M Pulido; J C González; Ferran Sanz
[Original articles published in Medicina Clínica during 30 years (1962-1992): number of authors, interval between acceptance and publication and bibliographic references].
Medicina clínica 1994;103(20):770-5.
1994: C Hernandez; Juan Sancho; M A Belmonte; C Sierra; Ferran Sanz
Validation of the medical expert system RENOIR.
Computers and biomedical research, an international journal 1994;27(6):456-71.
1994: Jose A Fontenla; J Osuna; E Rosa; M E Castro; T G-Ferreiro; I Loza-García; José María Calleja; Ferran Sanz; J Rodríguez; Enrique Raviña
Synthesis and atypical antipsychotic profile of some 2-(2-piperidinoethyl)benzocycloalkanones as analogues of butyrophenone.
Journal of medicinal chemistry 1994;37(16):2564-73.
1993: M Isabel Loza; Ferran Sanz; María Isabel Cadavid; M Honrubia; Francisco Orallo; Jose A Fontenla; José María Calleja; T Dot; F Manaut; M M Cid
Cyproheptadine analogues: synthesis, antiserotoninergic activity, and structure-activity relationships.
Journal of pharmaceutical sciences 1993;82(11):1090-3.
1993: Juan Sancho; J C González; A Patak; Ferran Sanz; Antonio Sitges-Serra
Introducing medical students to medical informatics.
Medical education 1993;27(6):479-83.
1993: M Isabel Loza; T G Ferreiro; Ferran Sanz; E Lozoya; J Rodriguez; F Manaut; Ignacio Verde; E Castro; Jose A Fontenla; I Cadavid
Antiserotoninergic activity of 2-aminoethylbenzocyclanones in rat aorta: structure-activity relationships.
Journal of pharmaceutical sciences 1993;82(5):513-7.
1992: A Verdaguer; A Patak; Juan Sancho; C Sierra; Ferran Sanz
Validation of the medical expert system PNEUMON-IA.
Computers and biomedical research, an international journal 1992;25(6):511-26.