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Renu Sarao

Research Profile

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Cheryl Wolting; Leanne E Wybenga-Groot; Emily K Griffiths; Brittany C Prevost; Renu Sarao; C Jane McGlade
Biochemical and computational analysis of LNX1 interacting proteins.
J Andrew Pospisilik; Claude Knauf; Nicholas Joza; Paule Benit; Michael Orthofer; Patrice Cani; Ingo Ebersberger; Tomoki Nakashima; Renu Sarao; Gregory Neely; Harald Esterbauer; Andrey Kozlov; C Ronald Kahn; Guido Kroemer; Pierre Rustin; Rémy Burcelin; Josef M Penninger
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Liyong Zhang; Michael S Anglesio; Maureen O'Sullivan; Fan Zhang; Ge Yang; Renu Sarao; P Nghiem Mai; Shane Cronin; Hiromitsu Hara; Nataliya Melnyk; Liheng Li; Teiji Wada; Peter P Liu; JASON FARRAR; Robert J Arceci; Poul H B Sorensen; Josef M Penninger
The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.

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All Publications

2011: Cheryl Wolting; Leanne E Wybenga-Groot; Emily K Griffiths; Brittany C Prevost; Renu Sarao; C Jane McGlade
Biochemical and computational analysis of LNX1 interacting proteins.
PloS one 2011;6(11):e26248.
2007: J Andrew Pospisilik; Claude Knauf; Nicholas Joza; Paule Benit; Michael Orthofer; Patrice Cani; Ingo Ebersberger; Tomoki Nakashima; Renu Sarao; Gregory Neely; Harald Esterbauer; Andrey Kozlov; C Ronald Kahn; Guido Kroemer; Pierre Rustin; Rémy Burcelin; Josef M Penninger
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Cell 2007;131(3):476-91.
2007: Liyong Zhang; Michael S Anglesio; Maureen O'Sullivan; Fan Zhang; Ge Yang; Renu Sarao; P Nghiem Mai; Shane Cronin; Hiromitsu Hara; Nataliya Melnyk; Liheng Li; Teiji Wada; Peter P Liu; JASON FARRAR; Robert J Arceci; Poul H B Sorensen; Josef M Penninger
The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.
Nature medicine 2007;13(9):1060-9.
2007: Keiji Kuba; Liyong Zhang; Yumiko Imai; Sara Arab; Manyin Chen; Yuichiro Maekawa; Michael Leschnik; Andreas Leibbrandt; Mato Markovic; Mato Makovic; Julia Schwaighofer; Nadine Beetz; Renata Musialek; G Greg Neely; Vukoslav Komnenovic; Ursula Kolm; Bernhard Metzler; Romeo Ricci; Hiromitsu Hara; Arabella Meixner; Mai Nghiem; Xin Chen; Fayez Dawood; Kit Man Wong; Renu Sarao; Eva Cukerman; Akinori Kimura; Lutz Hein; Johann G Thalhammer; Peter P Liu; Josef M Penninger
Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
Circulation research 2007;101(4):e32-42.
2006: Ursula Danilczyk; Renu Sarao; Christine Remy; Chahira Benabbas; Gerti Stange; Richter Andreas; Sudha Arya; J Andrew Pospisilik; Dustin Singer; Simone M R Camargo; Victoria Makrides; Tamara Ramadan; François Verrey; Carsten A Wagner; Josef M Penninger
Essential role for collectrin in renal amino acid transport.
Nature 2006;444(7122):1088-91.
2006: D Holstead Jones; Tomoki Nakashima; Otto H Sanchez; Ivona Kozieradzki; Svetlana V Komarova; Ildiko Sarosi; Sean Morony; Evelyn Rubin; Renu Sarao; Carlo V Hojilla; Vukoslav Komnenovic; Young-Yun Kong; Martin Schreiber; S Jeffrey Dixon; Stephen M Sims; Rama Khokha; Teiji Wada; Josef M Penninger
Regulation of cancer cell migration and bone metastasis by RANKL.
Nature 2006;440(7084):692-6.
2006: Gloria Valdés; Liomar Neves; Lauren Anton; Jenny Corthorn; Cecilia Chacón; Alfredo M Germain; David C Merrill; Carlos M Ferrario; Renu Sarao; Josef M Penninger; K Bridget Brosnihan
Distribution of angiotensin-(1-7) and ACE2 in human placentas of normal and pathological pregnancies.
Placenta 2006;27(2-3):200-7.
2005: Yumiko Imai; Keiji Kuba; Shuan Rao; Yi Huan; Feng Guo; Bin Guan; Peng Yang; Renu Sarao; Teiji Wada; Howard Leong-Poi; Michael A Crackower; Akiyoshi Fukamizu; Chi-Chung Hui; Lutz Hein; Stefan Uhlig; Arthur Slutsky; Chengyu Jiang; Josef M Penninger
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Nature 2005;436(7047):112-6.
2004: Myung-Shin Jeon; Alex Atfield; Venuprasad Poojary; Connie M Krawczyk; Renu Sarao; Chris Elly; Chun Yang; Sudha Arya; Kurt Bachmaier; Leon Su; Denis Bouchard; Russel Jones; Matthew A Gronski; Pamela S Ohashi; Teiji Wada; Debra Bloom; C Garrison Fathman; Yun-Cai Liu; Josef M Penninger
Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.
Immunity 2004;21(2):167-77.
2003: Gavin Y Oudit; Michael A Crackower; Urs Eriksson; Renu Sarao; Ivona Kozieradzki; Takehiko Sasaki; Junko Irie-Sasaki; Dominica Gidrewicz; Vitalyi O Rybin; Teiji Wada; Susan F Steinberg; Peter H Backx; Josef M Penninger
Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.
Circulation 2003;108(17):2147-52.
2003: K Bridget Brosnihan; Liomar Neves; JaNae Joyner; David B Averill; Mark C Chappell; Renu Sarao; Josef M Penninger; Carlos M Ferrario
Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy.
Hypertension 2003;42(4):749-53.
2003: Michael A Crackower; Nadine K Kolas; Junko Noguchi; Renu Sarao; Kazuhiro Kikuchi; Hiroyuki Kaneko; Eiji Kobayashi; Yasuhiro Kawai; Ivona Kozieradzki; Rushin Landers; Rong Mo; Chi-Chung Hui; Edward Nieves; Paula E Cohen; Lucy Osborne; Teiji Wada; Tetsuo Kunieda; Peter B Moens; Josef M Penninger
Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.
Science (New York, N.Y.) 2003;300(5623):1291-5.
2002: Michael A Crackower; Gavin Y Oudit; Ivona Kozieradzki; Renu Sarao; Hui Sun; Takehiko Sasaki; Emilio Hirsch; Akira Suzuki; Tetsuo Shioi; Junko Irie-Sasaki; Rajan Sah; Hai-Ying M Cheng; Vitalyi O Rybin; Giuseppe Lembo; Luigi Fratta; Antonio J Oliveira-dos-Santos; Jeffery L Benovic; C Ronald Kahn; Seigo Izumo; Susan F Steinberg; Matthias P Wymann; Peter H Backx; Josef M Penninger
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways.
Cell 2002;110(6):737-49.
2002: Michael A Crackower; Renu Sarao; Gavin Y Oudit; Chana Yagil; Ivona Kozieradzki; Sam E Scanga; Antonio J Oliveira-dos-Santos; Joan da Costa; Liyong Zhang; York Pei; James Scholey; Carlos M Ferrario; Armen S Manoukian; Mark C Chappell; Peter H Backx; Yoram Yagil; Josef M Penninger
Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Nature 2002;417(6891):822-8.
2001: Nina Jones; Daniel Voskas; Zubin Master; Renu Sarao; Jamie Jones; Daniel J Dumont
Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function.
EMBO reports 2001;2(5):438-45.
1998: Renu Sarao; Daniel J Dumont
Conditional transgene expression in endothelial cells.
Transgenic research 1998;7(6):421-7.
1998: Q Liu; Antonio J Oliveira-dos-Santos; Sanjeev Mariathasan; Denis Bouchard; J Jones; Renu Sarao; Ivona Kozieradzki; Pamela S Ohashi; Josef M Penninger; Daniel J Dumont
The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling.
The Journal of experimental medicine 1998;188(7):1333-42.