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Padmini Sarathchandra

Research Profile

Living Beings

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Osteogenesis Imperfecta

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Publications

TOP 3
Jennifer Richards; Zubair Sarang; Padmini Sarathchandra; Magdi H Yacoub; Si Chen; Adrian H Chester; Ismail El-Hamamsy; Jonathan T Butcher
Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling.
Manoraj Navaratnarajah; Padmini Sarathchandra; Adarsh Shah; Urszula Siedlecka; Priyanthi Dias; Ajay Gandhi; Michael Ibrahim; Carin van Doorn; Magdi H Yacoub; Cesare M N Terracciano
Influence of ivabradine on reverse remodelling during mechanical unloading.
Padmini Sarathchandra; Ryszard T Smolenski; Adrian H Chester; Steven Goldstein; Albert E Heacox; Magdi H Yacoub; Ada H Y Yuen; Patricia M Taylor
Impact of γ-irradiation on extracellular matrix of porcine pulmonary valves.

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All Publications

2013: Jennifer Richards; Zubair Sarang; Padmini Sarathchandra; Magdi H Yacoub; Si Chen; Adrian H Chester; Ismail El-Hamamsy; Jonathan T Butcher
Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling.
The American journal of pathology 2013;182(5):1922-31.
2013: Manoraj Navaratnarajah; Padmini Sarathchandra; Adarsh Shah; Urszula Siedlecka; Priyanthi Dias; Ajay Gandhi; Michael Ibrahim; Carin van Doorn; Magdi H Yacoub; Cesare M N Terracciano
Influence of ivabradine on reverse remodelling during mechanical unloading.
Cardiovascular research 2013;97(2):230-9.
2012: Padmini Sarathchandra; Ryszard T Smolenski; Adrian H Chester; Steven Goldstein; Albert E Heacox; Magdi H Yacoub; Ada H Y Yuen; Patricia M Taylor
Impact of γ-irradiation on extracellular matrix of porcine pulmonary valves.
The Journal of surgical research 2012;176(2):376-85.
2012: Kristy L Cloyd; Francesca Colazzo; Ismail El-Hamamsy; Eileen Gentleman; Molly M Gentleman; Martin Hedegaard; Padmini Sarathchandra; Suwimon Boonrungsiman; Adrian H Chester; Magdi H Yacoub; Molly M Stevens
Characterization of porcine aortic valvular interstitial cell 'calcified' nodules.
PloS one 2012;7(10):e48154.
2012: Huijun Ying; Hongmei Fu; Ann M McCormack; Klaus Okkenhaug; Marlene L Rose; Padmini Sarathchandra; Federica M Marelli-Berg
Genetic or pharmaceutical blockade of phosphoinositide 3-kinase p110δ prevents chronic rejection of heart allografts.
PloS one 2012;7(3):e32892.
2011: Leanne E Felkin; Renée Germack; Jesús M Gómez-Salinero; Marina M López-Olañeta; Takuya Narita; Nadia Rosenthal; Padmini Sarathchandra; Yasunori Shintani; Ken Suzuki; Kunihiko Takahashi; Paul J R Barton; Enrique Lara-Pezzi
Calcineurin splicing variant calcineurin Aβ1 improves cardiac function after myocardial infarction without inducing hypertrophy.
Circulation 2011;123(24):2838-47.
2011: Francesca Colazzo; Padmini Sarathchandra; Ryszard T Smolenski; Adrian H Chester; Yuan-Tsan Tseng; Jan T Czernuszka; Magdi H Yacoub; Patricia M Taylor
Extracellular matrix production by adipose-derived stem cells: implications for heart valve tissue engineering.
Biomaterials 2011;32(1):119-27.
2010: Ying Xu; Adrian H Chester; Batool Hariri; Ann McCormack; Padmini Sarathchandra; Marlene L Rose
The indirect alloimmune response causes microvascular endothelial dysfunction-a possible role for alloantibody.
Transplantation 2010;90(11):1157-64.
2010: Balakrishnan Mahesh; Hon Sing Leong; K Sukumaran Nair; Ann McCormack; Padmini Sarathchandra; Marlene L Rose
Autoimmunity to vimentin potentiates graft vasculopathy in murine cardiac allografts.
Transplantation 2010;90(1):4-13.
2010: Lars Bochmann; Padmini Sarathchandra; Federica Mori; Enrique Lara-Pezzi; Domenico Lazzaro; Nadia Rosenthal
Revealing new mouse epicardial cell markers through transcriptomics.
PloS one 2010;5(6):e11429.
2009: Sarah Din; Padmini Sarathchandra; Magdi H Yacoub; Adrian H Chester
Interaction between bone morphogenetic proteins and endothelin-1 in human pulmonary artery smooth muscle.
Vascular pharmacology 2009;51(5-6):344-9.
2009: Ismail El-Hamamsy; Kartik Balachandran; Magdi H Yacoub; Louis M Stevens; Padmini Sarathchandra; Patricia M Taylor; Ajit P Yoganathan; Adrian H Chester
Endothelium-dependent regulation of the mechanical properties of aortic valve cusps.
Journal of the American College of Cardiology 2009;53(16):1448-55.
2008: Enrique Lara-Pezzi; Leanne E Felkin; Emma J Birks; Padmini Sarathchandra; Kalyani D Panse; Robert George; Jennifer L Hall; Magdi H Yacoub; Nadia Rosenthal; Paul J R Barton
Expression of follistatin-related genes is altered in heart failure.
Endocrinology 2008;149(11):5822-7.
2008: Emma J Birks; Najma Latif; Karine Enesa; Tonje Folkvang; Le Anh Luong; Padmini Sarathchandra; Mak Khan; Huib Ovaa; Cesare M Terracciano; Paul J R Barton; Magdi H Yacoub; Paul C Evans
Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy.
Cardiovascular research 2008;79(3):472-80.
2008: Adrian H Chester; John D B Kershaw; Padmini Sarathchandra; Magdi H Yacoub
Localisation and function of nerves in the aortic root.
Journal of molecular and cellular cardiology 2008;44(6):1045-52.
2008: Omar Mangoush; Thanos Athanasiou; Koki Nakamura; Philip Johnson; Ryszart Smoienski; Padmini Sarathchandra; Tim Oury; Adrian H Chester; Mohamed Amrani
Antioxidant properties of the internal thoracic artery and the radial artery.
Heart, lung & circulation 2008;17(1):40-7.
2007: Enrique Lara-Pezzi; Nadine Winn; Angelika Paul; Karl McCullagh; Esfir Slominsky; Maria Paola Santini; Foteini Mourkioti; Padmini Sarathchandra; Satsuki Fukushima; Ken Suzuki; Nadia Rosenthal
A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration.
The Journal of cell biology 2007;179(6):1205-18.
2007: Lana Osman; Adrian H Chester; Padmini Sarathchandra; Najma Latif; Wenfang Meng; Patricia M Taylor; Magdi H Yacoub
A novel role of the sympatho-adrenergic system in regulating valve calcification.
Circulation 2007;116(11 Suppl):I282-7.
2007: Balakrishnan Mahesh; Hon Sing Leong; Ann McCormack; Padmini Sarathchandra; Angela Holder; Marlene L Rose
Autoantibodies to vimentin cause accelerated rejection of cardiac allografts.
The American journal of pathology 2007;170(4):1415-27.
2007: Najma Latif; Padmini Sarathchandra; Penny S Thomas; Joseph W Antoniw; Puspa Batten; Adrian H Chester; Patricia M Taylor; Magdi H Yacoub
Characterization of structural and signaling molecules by human valve interstitial cells and comparison to human mesenchymal stem cells.
The Journal of heart valve disease 2007;16(1):56-66.
2006: Christopher J Kelsall; Adrian H Chester; Padmini Sarathchandra; Donald Singer
Expression and localization of C-type natriuretic peptide in human vascular smooth muscle cells.
Vascular pharmacology 2006;45(6):368-73.
2006: John V Terrovitis; Jeff W M Bulte; Sajiram Sarvananthan; Lindsey Crowe; Padmini Sarathchandra; Puspa Batten; Eleftherios Sachlos; Adrian H Chester; Jan T Czernuszka; David N Firmin; Patricia M Taylor; Magdi H Yacoub
Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering.
Tissue engineering 2006;12(10):2765-75.
2006: Puspa Batten; Padmini Sarathchandra; Joseph W Antoniw; Szun Szun Tay; Mark W Lowdell; Patricia M Taylor; Magdi H Yacoub
Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves.
Tissue engineering 2006;12(8):2263-73.
2006: Ching-Hsin Ku; Philip H Johnson; Puspa Batten; Padmini Sarathchandra; Rachel C Chambers; Patricia M Taylor; Magdi H Yacoub; Adrian H Chester
Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch.
Cardiovascular research 2006;71(3):548-56.
2006: Satsuki Fukushima; Steven R Coppen; Anabel Varela-Carver; Kenichi Yamahara; Padmini Sarathchandra; Ryszard T Smolenski; Magdi H Yacoub; Ken Suzuki
A novel strategy for myocardial protection by combined antibody therapy inhibiting both P-selectin and intercellular adhesion molecule-1 via retrograde intracoronary route.
Circulation 2006;114(1 Suppl):I251-6.
2006: Magdi H Yacoub; Loes M A Klieverik; Giovanni Melina; Sue E R Edwards; Padmini Sarathchandra; Ad J J C Bogers; Umberto Squarcia; Guido Sani; Lex van herwerden; Johanna J M Takkenberg
An evaluation of the Ross operation in adults.
The Journal of heart valve disease 2006;15(4):531-9.
2006: Satsuki Fukushima; Steven R Coppen; Anabel Varela-Carver; Gemma Brindley; Kenichi Yamahara; Padmini Sarathchandra; Magdi H Yacoub; Ken Suzuki
Enhanced efficiency of superoxide dismutase-induced cardioprotection by retrograde intracoronary administration.
Cardiovascular research 2006;69(2):459-65.
2006: Najma Latif; Padmini Sarathchandra; Patricia M Taylor; Joseph W Antoniw; N Brand; Magdi H Yacoub
Characterization of molecules mediating cell-cell communication in human cardiac valve interstitial cells.
Cell biochemistry and biophysics 2006;45(3):255-64.
2005: Najma Latif; Padmini Sarathchandra; Patricia M Taylor; Joseph W Antoniw; Magdi H Yacoub
Localization and pattern of expression of extracellular matrix components in human heart valves.
The Journal of heart valve disease 2005;14(2):218-27.
2005: Padmini Sarathchandra; John P Cassella; S Yousuf Ali
Enzyme histochemical localisation of alkaline phosphatase activity in osteogenesis imperfecta bone and growth plate: a preliminary study.
Micron (Oxford, England : 1993) 2005;36(7-8):715-20.
2005: Padmini Sarathchandra; F Michael Pope
Unexpected ultrastructral changes in bone osteiod collagens in osteogenesis imperfecta.
Micron (Oxford, England : 1993) 2005;36(7-8):696-702.
2005: Najma Latif; Padmini Sarathchandra; Patricia M Taylor; Joseph W Antoniw; Magdi H Yacoub
Molecules mediating cell-ECM and cell-cell communication in human heart valves.
Cell biochemistry and biophysics 2005;43(2):275-87.
2004: TM MacLeod; Padmini Sarathchandra; G Williams; Roy Sanders; Colin J Green
The diamond CO2 laser as a method of improving the vascularisation of a permanent collagen implant.
Burns : journal of the International Society for Burn Injuries 2004;30(7):704-12.
2004: TM MacLeod; Padmini Sarathchandra; G Williams; Roy Sanders; Colin J Green
Evaluation of a porcine origin acellular dermal matrix and small intestinal submucosa as dermal replacements in preventing secondary skin graft contraction.
Burns : journal of the International Society for Burn Injuries 2004;30(5):431-7.
2002: Ahmet Akar; Davut G l; Zeyir Erdem; Padmini Sarathchandra; Carolyn Tysoe; Mike Pope
Acrogeric Ehlers-Danlos syndrome type IV: report of a new patient with additional findings.
European journal of dermatology : EJD 2002;12(5):428-31.
2002: Roberto Motterlini; James E Clark; Roberta Foresti; Padmini Sarathchandra; Brian E Mann; Colin J Green
Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities.
Circulation research 2002;90(2):E17-24.
2002: Padmini Sarathchandra; John P Cassella; S Yousuf Ali
Ultrastructural localization of proteoglycans in bone in osteogenesis imperfecta as demonstrated by Cuprolinic Blue staining.
Journal of bone and mineral metabolism 2002;20(5):288-93.
2000: Padmini Sarathchandra; F Michael Pope; Mike V Kayser; S Yousuf Ali
A light and electron microscopic study of osteogenesis imperfecta bone samples, with reference to collagen chemistry and clinical phenotype.
The Journal of pathology 2000;192(3):385-95.
2000: Ivan A Sammut; K Burton; Elizabeth Balogun; Padmini Sarathchandra; K J Brooks; Timothy E Bates; Colin J Green
Time-dependent impairment of mitochondrial function after storage and transplantation of rabbit kidneys.
Transplantation 2000;69(7):1265-75.
2000: James E Clark; Roberta Foresti; Padmini Sarathchandra; H Kaur; Colin J Green; Roberto Motterlini
Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction.
American journal of physiology. Heart and circulatory physiology 2000;278(2):H643-51.
1999: Padmini Sarathchandra; F Michael Pope; S Yousuf Ali
Morphometric analysis of type I collagen fibrils in the osteoid of osteogenesis imperfecta.
Calcified tissue international 1999;65(5):390-5.
1999: Padmini Sarathchandra; Mike V Kayser; S Yousuf Ali
Abnormal mineral composition of osteogenesis imperfecta bone as determined by electron probe X-ray microanalysis on conventional and cryosections.
Calcified tissue international 1999;65(1):11-5.
1999: Roberta Foresti; Padmini Sarathchandra; James E Clark; Colin J Green; Roberto Motterlini
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis.
The Biochemical journal 1999;339 ( Pt 3)():729-36.
1998: Ivan A Sammut; Roberta Foresti; James E Clark; D J Exon; M J Vesely; Padmini Sarathchandra; Colin J Green; Roberto Motterlini
Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase-1.
British journal of pharmacology 1998;125(7):1437-44.
1996: Padmini Sarathchandra; F M Pope; S Yousuf Ali
An ultrastructural and immunogold localization study of proteoglycans associated with the osteocytes of fetal bone in osteogenesis imperfecta.
Calcified tissue international 1996;58(6):435-42.
1995: M A Hidalgo; Padmini Sarathchandra; P R Fryer; Barry J Fuller; C J Green
Effects of hypothermic storage on the vascular endothelium: a scanning electron microscope study of morphological change in human vein.
The Journal of cardiovascular surgery 1995;36(6):525-32.
1995: M A Hidalgo; Padmini Sarathchandra; P R Fryer; Barry J Fuller; C J Green
Scanning electron microscopic changes in morphology of pulmonary endothelium in rat lung isografts following hypothermic ischaemic storage and transplantation.
International journal of experimental pathology 1995;76(5):339-51.
1993: H Nishikawa; P R Fryer; Padmini Sarathchandra; S Manek; A Charlett; C J Green
Ultrastructural changes in rat adipomusculocutaneous flaps during warm ischaemic storage and reperfusion.
International journal of experimental pathology 1993;74(1):45-53.
1990: M A Pickford; C J Green; Padmini Sarathchandra; P R Fryer
Ultrastructural changes in rat lungs after 48 h cold storage with and without reperfusion.
International journal of experimental pathology 1990;71(4):513-28.