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Karuppagounder Saravanan

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Rebecca Banerjee; Karuppagounder S Saravanan; Bobby Thomas; Kizhakke M Sindhu; Kochupurackal P Mohanakumar
Evidence for hydroxyl radical scavenging action of nitric oxide donors in the protection against 1-methyl-4-phenylpyridinium-induced neurotoxicity in rats.
Bobby Thomas; Karuppagounder S Saravanan; Kochupurackal P Mohanakumar
In vitro and in vivo evidences that antioxidant action contributes to the neuroprotective effects of the neuronal nitric oxide synthase and monoamine oxidase-B inhibitor, 7-nitroindazole.
Karuppagounder S Senthilkumar; Karuppagounder S Saravanan; Goutam Chandra; Kizhakke M Sindhu; A Jayakrishnan; Kochupurackal P Mohanakumar
Unilateral implantation of dopamine-loaded biodegradable hydrogel in the striatum attenuates motor abnormalities in the 6-hydroxydopamine model of hemi-parkinsonism.

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All Publications

2008: Rebecca Banerjee; Karuppagounder S Saravanan; Bobby Thomas; Kizhakke M Sindhu; Kochupurackal P Mohanakumar
Evidence for hydroxyl radical scavenging action of nitric oxide donors in the protection against 1-methyl-4-phenylpyridinium-induced neurotoxicity in rats.
Neurochemical research 2008;33(6):985-95.
2008: Bobby Thomas; Karuppagounder S Saravanan; Kochupurackal P Mohanakumar
In vitro and in vivo evidences that antioxidant action contributes to the neuroprotective effects of the neuronal nitric oxide synthase and monoamine oxidase-B inhibitor, 7-nitroindazole.
Neurochemistry international 2008;52(6):990-1001.
2007: Karuppagounder S Senthilkumar; Karuppagounder S Saravanan; Goutam Chandra; Kizhakke M Sindhu; A Jayakrishnan; Kochupurackal P Mohanakumar
Unilateral implantation of dopamine-loaded biodegradable hydrogel in the striatum attenuates motor abnormalities in the 6-hydroxydopamine model of hemi-parkinsonism.
Behavioural brain research 2007;184(1):11-8.
2007: Rebecca Banerjee; Sen Sreetama; Karuppagounder S Saravanan; Sailendra Nath Dey; Kochupurackal P Mohanakumar
Apoptotic mode of cell death in substantia nigra following intranigral infusion of the parkinsonian neurotoxin, MPP+ in Sprague-Dawley rats: cellular, molecular and ultrastructural evidences.
Neurochemical research 2007;32(7):1238-47.
2007: Karuppagounder S Saravanan; Kizhakke M Sindhu; Kochupurackal P Mohanakumar
Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model.
Journal of pineal research 2007;42(3):247-53.
2006: Rebecca Banerjee; Sen Sreetama; Karuppagounder S Saravanan; Goutam Chandra; Sailendra Nath De; Kochupurackal P Mohanakumar
Intrastriatal infusion of the Parkinsonian neurotoxin, MPP(+), induces damage of striatal cell nuclei in Sprague-Dawley rats.
Journal of chemical neuroanatomy 2006;32(2-4):90-100.
2006: Amichand Dairam; E M Antunes; Karuppagounder S Saravanan; Santy Daya
Non-steroidal anti-inflammatory agents, tolmetin and sulindac, inhibit liver tryptophan 2,3-dioxygenase activity and alter brain neurotransmitter levels.
Life sciences 2006;79(24):2269-74.
2006: Karuppagounder S Saravanan; Kizhakke M Sindhu; Karuppagounder S Senthilkumar; Kochupurackal P Mohanakumar
L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats.
Neurochemistry international 2006;49(1):28-40.
2006: Kizhakke M Sindhu; Rebecca Banerjee; Karuppagounder S Senthilkumar; Karuppagounder S Saravanan; B China Raju; J Madhusudana Rao; Kochupurackal P Mohanakumar
Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine.
Pharmacology, biochemistry, and behavior 2006;84(2):321-9.
2005: Kizhakke M Sindhu; Karuppagounder S Saravanan; Kochupurackal P Mohanakumar
Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion.
Brain research 2005;1051(1-2):25-34.
2005: Karuppagounder S Saravanan; Kizhakke M Sindhu; Kochupurackal P Mohanakumar
Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease.
Brain research 2005;1049(2):147-55.
2004: Himant Maharaj; Deepa S Maharaj; Karuppagounder S Saravanan; Kochupurackal P Mohanakumar; Santy Daya
Aspirin curtails the acetaminophen-induced rise in brain norepinephrine levels.
Metabolic brain disease 2004;19(1-2):71-7.
2004: Deepa S Maharaj; Karuppagounder S Saravanan; Himant Maharaj; Kochupurackal P Mohanakumar; Santy Daya
Acetaminophen and aspirin inhibit superoxide anion generation and lipid peroxidation, and protect against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Neurochemistry international 2004;44(5):355-60.
2003: Hina Mehta; Karuppagounder S Saravanan; Kochupurackal P Mohanakumar
Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice.
Behavioural brain research 2003;145(1-2):31-6.
2003: Krishnamurthy Sairam; Karuppagounder S Saravanan; Rebecca Banerjee; Kochupurackal P Mohanakumar
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Brain research 2003;966(2):245-52.
2002: Tuhinadri Sen; C A Abdulsalam; Sanchayita Pal; S Sen; S Karmakar; Karuppagounder S Saravanan; A K Nag Chaudhuri
Effect of amitriptyline on gastric ulceration.
Fundamental & clinical pharmacology 2002;16(4):311-5.