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Fazlul Sarkar

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Asfar S Azmi; Ginny W Bao; Jiankun Gao; Ramzi M Mohammad; Fazlul H Sarkar
Network insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a review.
Yi Tan; Lucio Miele; Fazlul H Sarkar; Qiong Wu; Jun Xia; Zhiwei Wang
Systems biology approaches in identifying the targets of natural compounds for cancer therapy.
Mujahid Yusufi; Fazlul H Sarkar; K Venkateswara Swamy; Amro Aboukameel; Sanjeev Banerjee; Ejazuddin M Khan; Sandhya Khatal; Momin Mohammad; Subhash Padhye
Synthesis, characterization and anti-tumor activity of novel thymoquinone analogs against pancreatic cancer.

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All Publications

2013: Asfar S Azmi; Ginny W Bao; Jiankun Gao; Ramzi M Mohammad; Fazlul H Sarkar
Network insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a review.
Current drug discovery technologies 2013;10(2):147-54.
2013: Yi Tan; Lucio Miele; Fazlul H Sarkar; Qiong Wu; Jun Xia; Zhiwei Wang
Systems biology approaches in identifying the targets of natural compounds for cancer therapy.
Current drug discovery technologies 2013;10(2):139-46.
2013: Mujahid Yusufi; Fazlul H Sarkar; K Venkateswara Swamy; Amro Aboukameel; Sanjeev Banerjee; Ejazuddin M Khan; Sandhya Khatal; Momin Mohammad; Subhash Padhye
Synthesis, characterization and anti-tumor activity of novel thymoquinone analogs against pancreatic cancer.
Bioorganic & medicinal chemistry letters 2013;23(10):3101-4.
2013: Shuo Wang; Yanning Wu; Jacob J Oblak; Fazlul H Sarkar; Sanjeev Banerjee; Marcello P Castelvetere; Xuequn Chen; Theresa M Filtz; Xiaoqing Guan; Yuning Hou; Bhanu P Jena; Chunying Li
CXCR2 macromolecular complex in pancreatic cancer: a potential therapeutic target in tumor growth.
Translational oncology 2013;6(2):216-25.
2013: Yingjie Yu; Fazlul H Sarkar; Adhip P N Majumdar
Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens.
Translational oncology 2013;6(2):180-6.
2013: Shuping Yin; Sanjeev Banerjee; R Daniel Bonfil; Fazlul H Sarkar; Seema Sethi; Liping Xu; Kaladhar B Reddy
Tumor-initiating cells and FZD8 play a major role in drug resistance in triple-negative breast cancer.
Molecular cancer therapeutics 2013;12(4):491-8.
2013: Zhiwei Wang; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Bin Bao; Murray Korc; Yiwei Li; Fazlul H Sarkar
Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype.
Journal of cellular physiology 2013;228(3):556-62.
2013: Mansi A Parasramka; Fazlul H Sarkar; Shadan Ali; Sanjeev Banerjee; Tara Deryavoush; Smiti Vaid Gupta
Garcinol sensitizes human pancreatic adenocarcinoma cells to gemcitabine in association with microRNA signatures.
Molecular nutrition & food research 2013;57(2):235-48.
2013: Seema Sethi; Gregory Dyson; Dejuan Kong; Sue Land; Wael A Sakr; Fazlul H Sarkar
Comprehensive molecular oncogenomic profiling and miRNA analysis of prostate cancer.
American journal of translational research 2013;5(2):200-11.
2013: Joy Tang; Shirish M Gadgeel; Rasha Salama; Fazlul H Sarkar; Aamir Ahmad
Erlotinib resistance in lung cancer: current progress and future perspectives.
Frontiers in pharmacology 2013;4():15.
2013: Archana Thakur; Elyse Tomaszewski; Hiroshi Yano; Sri Vidya Kondadasula; Fazlul H Sarkar; Dana Schalk; Lawrence G Lum
Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE2 dependent pathway.
Journal of translational medicine 2013;11():35.
2013: Zhiwei Wang; Jiateng Zhong; Hiroyuki Inuzuka; Pengda Liu; Fazlul H Sarkar; Lixin Wan; Wenyi Wei
Cdc20: a potential novel therapeutic target for cancer treatment.
Current pharmaceutical design 2013;19(18):3210-4.
2013: Ashhar S Ali; Shadan Ali; Bin Bao; Philip A Philip; Aamir Ahmad; Fazlul H Sarkar
The role of cancer stem cells and miRNAs in defining the complexities of brain metastasis.
Journal of cellular physiology 2013;228(1):36-42.
2012: Agnes Patzkó; Mario A Saporta; Fazlul H Sarkar; Yunhong Bai; Lisa M Dillon; M Laura Feltri; John Kamholz; István Katona; Daniel Kirschner; Domenica Vizzuso; Suola Wang; Lawrence Wrabetz; Xingyao Wu; chris hall
Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.
Brain : a journal of neurology 2012;135(Pt 12):3551-66.
2012: Bin Bao; Ginny Bao; Dejuan Kong; Yiwei Li; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Fazlul H Sarkar
Targeting CSC-related miRNAs for cancer therapy by natural agents.
Current drug targets 2012;13(14):1858-68.
2012: Rohan Pradhan; Rainer Schobert; Alok Vyas; Aamir Ahmad; Bernhard Biersack; Prasad Dandawate; Subhash Padhye; Fazlul H Sarkar
From body art to anticancer activities: perspectives on medicinal properties of henna.
Current drug targets 2012;13(14):1777-98.
2012: Jun Xia; K M Wahidur Rahman; Aamir Ahmad; Sanjeev Banerjee; Bin Bao; Zhiwen Chen; Qiaoling Duan; Jian Geng; Jia Ma; Lucio Miele; Fazlul H Sarkar; Ying Shi; Zhiwei Wang
Genistein inhibits cell growth and induces apoptosis through up-regulation of miR-34a in pancreatic cancer cells.
Current drug targets 2012;13(14):1750-6.
2012: Aamir Ahmad; Shadan Ali; Sanjeev Banerjee; Bin Bao; Bernhard Biersack; Dejuan Kong; Yiwei Li; Subhash B Padhye; Sarah H Sarkar; Rainer Schobert; Sebastian Seibt; Amro Aboukameel; Fazlul H Sarkar
Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling.
Carcinogenesis 2012;33(12):2450-6.
2012: Zhiwei Wang; Jiateng Zhong; Hiroyuki Inuzuka; Pengda Liu; Fazlul H Sarkar; Yi Sun; Wenyi Wei
Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2.
Oncotarget 2012;3(11):1294-300.
2012: Asfar S Azmi; Fazlul H Sarkar
Prostate cancer stem cells: molecular characterization for targeted therapy.
Asian journal of andrology 2012;14(5):659-60.
2012: Asfar S Azmi; Ramzi M Mohammad; Fazlul H Sarkar
Can network pharmacology rescue neutraceutical cancer research?
Drug discovery today 2012;17(15-16):807-9.
2012: Uzma Shamim; Sheikh M Hadi; Sarmad Hanif; Fazlul H Sarkar; Bin Bao; Abdulmajeed Albanyan; Ramzi M Mohammad; Zhiwei Wang; Frances W J Beck; Sanjeev Banerjee; Asfar S Azmi
Resveratrol-induced apoptosis is enhanced in low pH environments associated with cancer.
Journal of cellular physiology 2012;227(4):1493-500.
2012: Julian J Raffoul; Fazlul H Sarkar; Omer Kucuk; Gilda G Hillman
Dietary agents in cancer chemoprevention and treatment.
Journal of oncology 2012;2012():749310.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Subhash B Padhye; Amro Aboukameel; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Seema Sethi; Fazlul H Sarkar
Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment.
PloS one 2012;7(12):e50165.
2012: Joy Tang; Aamir Ahmad; Fazlul H Sarkar
The Role of MicroRNAs in Breast Cancer Migration, Invasion and Metastasis.
International journal of molecular sciences 2012;13(10):13414-37.
2012: Saba Haq; Ramzi M Mohammad; Shadan Ali; Fazlul H Sarkar
The complexities of epidemiology and prevention of gastrointestinal cancers.
International journal of molecular sciences 2012;13(10):12556-72.
2012: Archana Thakur; Fazlul H Sarkar; Dana Schalk; ASFAR AZMI; Sanjeev Banerjee; Lawrence George Lum; Ramzi Mohommad
Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells.
PloS one 2012;7(11):e47520.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Subhash Padhye; Aamir Ahmad; Shadan Ali; Asfar S Azmi; Sanjeev Banerjee; Fazlul H Sarkar
Hypoxia induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF.
PloS one 2012;7(8):e43726.
2012: Irfana Muqbil; Fazlul H Sarkar; Bin Bao; Frances W J Beck; S M Hadi; Ramzi M Mohammad; Asfar S Azmi
Old wine in a new bottle: the Warburg effect and anticancer mechanisms of resveratrol.
Current pharmaceutical design 2012;18(12):1645-54.
2012: Bin Bao; Subhash Padhye; Zhiwei Wang; Asfar S Azmi; Sanjeev Banerjee; Yiwei Li; Aamir Ahmad; Farah Logna; Dejuan Kong; Shadan Ali; Fazlul H Sarkar
Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression.
Cancer research 2012;72(1):335-45.
2011: Asfar S Azmi; Bin Bao; Frances W J Beck; Ramzi M Mohammad; Fazlul H Sarkar
Aberrant epigenetic grooming of miRNAs in pancreatic cancer: a systems biology perspective.
Epigenomics 2011;3(6):747-59.
2011: Asfar S Azmi; Sanjeev Banerjee; Bin Bao; Mai N Maitah; Ramzi M Mohammad; Subhash Padhye; Philip A Philip; Shadan Ali; Fazlul H Sarkar
Network modeling of CDF treated pancreatic cancer cells reveals a novel c-myc-p73 dependent apoptotic mechanism.
American journal of translational research 2011;3(4):374-82.
2011: Asfar S Azmi; Sanjeev Banerjee; Bin Bao; Frances W J Beck; Minsig Choi; Main Maitah; Philip A Philip; Fazlul H Sarkar; Tony F Shields; Zhiwei Wang; Shadan Ali; Ramzi M Mohammad
Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors.
Oncotarget 2011;2(5):378-92.
2011: Zhiwei Wang; Aamir Ahmad; Yiwei Li; Asfar S Azmi; Lucio Miele; Fazlul H Sarkar
Targeting notch to eradicate pancreatic cancer stem cells for cancer therapy.
Anticancer research 2011;31(4):1105-13.
2011: Sanjeev Banerjee; Dejuan Kong; Asfar S Azmi; Zhiwei Wang; Aamir Ahmad; Seema Sethi; Fazlul H Sarkar
Restoring sensitivity to oxaliplatin by a novel approach in gemcitabine-resistant pancreatic cancer cells in vitro and in vivo.
International journal of cancer. Journal international du cancer 2011;128(5):1240-50.
2011: Asfar S Azmi; Philip A Philip; F W J Beck; Z Wang; S Banerjee; Shaomeng Wang; D Yang; Fazlul H Sarkar; Ramzi M Mohammad
MI-219-zinc combination: a new paradigm in MDM2 inhibitor-based therapy.
Oncogene 2011;30(1):117-26.
2011: Zhiwei Wang; Aamir Ahmad; Shadan Ali; Asfar S Azmi; Sanjeev Banerjee; Bin Bao; Jiankun Gao; Jason R Gunn; Dejuan Kong; Murray Korc; Yiwei Li; Lucio Miele; Ramzi M Mohammad; Fazlul H Sarkar
Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
PloS one 2011;6(6):e20537.
2011: Zhiwei Wang; Yiwei Li; Aamir Ahmad; Sanjeev Banerjee; Asfar S Azmi; Dejuan Kong; Christine Wojewoda; Lucio Miele; Fazlul H Sarkar
Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells.
Journal of cellular biochemistry 2011;112(1):78-88.
2010: Zhiwei Wang; Yiwei Li; Aamir Ahmad; Asfar S Azmi; Dejuan Kong; Sanjeev Banerjee; Fazlul H Sarkar
Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2010;13(4-5):109-18.