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Christoph Sarrazin

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Julia Dietz; Daniel Fitting; Caterina Füller; Eva Herrmann; Thomas Lengauer; Ulrike Mihm; Sven-Eric Schelhorn; Simone Susser; Gerlinde Teuber; Heiner Wedemeyer; Martin Walter Welker; Stefan Zeuzem; Thomas Berg; Martin Däumer; Christoph Sarrazin
Deep Sequencing Reveals Mutagenic Effects of Ribavirin during Monotherapy of Hepatitis C Virus Genotype 1-Infected Patients.
Sandra Westhaus; Ilka Wappler; Clemens Agné; Dorothea Bankwitz; Sandra Ciesek; Stefanie Ernst; Maren Luchtefeld; Michael P Manns; Thomas Pietschmann; Katrin Rohrmann; Christoph Sarrazin; Bernhard Schieffer; Thomas von Hahn
Characterization of the inhibition of hepatitis C virus entry by In vitro-generated and patient-derived oxidized low-density lipoprotein.
Mireen Friedrich-Rust; Eva Herrmann; K Matschenz; J Petersen; M D Schneider; F Schulze; Y Shi; Stefan Zeuzem; P Buggisch; R J de Knegt; V Dries; Christoph Sarrazin
Acoustic radiation force impulse imaging for non-invasive assessment of liver fibrosis in chronic hepatitis B.

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All Publications

2013: Julia Dietz; Daniel Fitting; Caterina Füller; Eva Herrmann; Thomas Lengauer; Ulrike Mihm; Sven-Eric Schelhorn; Simone Susser; Gerlinde Teuber; Heiner Wedemeyer; Martin Walter Welker; Stefan Zeuzem; Thomas Berg; Martin Däumer; Christoph Sarrazin
Deep Sequencing Reveals Mutagenic Effects of Ribavirin during Monotherapy of Hepatitis C Virus Genotype 1-Infected Patients.
Journal of virology 2013;87(11):6172-81.
2013: Sandra Westhaus; Ilka Wappler; Clemens Agné; Dorothea Bankwitz; Sandra Ciesek; Stefanie Ernst; Maren Luchtefeld; Michael P Manns; Thomas Pietschmann; Katrin Rohrmann; Christoph Sarrazin; Bernhard Schieffer; Thomas von Hahn
Characterization of the inhibition of hepatitis C virus entry by In vitro-generated and patient-derived oxidized low-density lipoprotein.
Hepatology (Baltimore, Md.) 2013;57(5):1716-24.
2013: Mireen Friedrich-Rust; Eva Herrmann; K Matschenz; J Petersen; M D Schneider; F Schulze; Y Shi; Stefan Zeuzem; P Buggisch; R J de Knegt; V Dries; Christoph Sarrazin
Acoustic radiation force impulse imaging for non-invasive assessment of liver fibrosis in chronic hepatitis B.
Journal of viral hepatitis 2013;20(4):240-7.
2013: J Peveling-Oberhag; Christoph Sarrazin; S Susser; Stefan Zeuzem; H Farnik; Eva Herrmann; Bernd Kronenberger; Wolf Peter Hofmann
Dynamics of hepatitis B virus quasispecies heterogeneity and virologic response in patients receiving low-to-moderate genetic barrier nucleoside analogs.
Journal of viral hepatitis 2013;20(4):234-9.
2013: Viola Knop; Bernd Möller; Konrad Neumann; Jens Rasenack; Christoph Sarrazin; Ulrich Spengler; Gerlinde Teuber; Stefan Zeuzem; Peter Buggisch; Tilman Gerlach; Holger Hinrichsen; Hartwig Klinker; Thomas Berg
Prediction of minimal residual viremia in HCV type 1 infected patients receiving interferon-based therapy.
Annals of hepatology 2013;12(2):190-8.
2013: Janett Fischer; Jacob George; Christoph Sarrazin; Stephan Böhm; Thomas Berg
Impact of cohort size and host factors on combined analysis of interleukin 28B rs12979860 and rs8099917 in hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2013;57(1):416-7.
2012: Nicole Forestier; Joerg Albert; Jörg Bojunga; Georg Dultz; Antonia Gaus; Ludmila Gerber; Eva Herrmann; Thierry Poynard; Christoph Sarrazin; Maximilian-David Schneider; Stefan Zeuzem; Mireen Friedrich-Rust
Acoustic radiation force impulse imaging for evaluation of antiviral treatment response in chronic hepatitis C.
Journal of gastrointestinal and liver diseases : JGLD 2012;21(4):367-73.
2012: Martin Walter Welker; Christoph Welsch; Stefan Zeuzem; S Susser; C Füller; Eva Herrmann; Bernd Kronenberger; D Perner; Christoph Sarrazin
Modulation of replication efficacy of the hepatitis C virus replicon Con1 by site-directed mutagenesis of an NS4B aminoterminal basic leucine zipper.
Journal of viral hepatitis 2012;19(11):775-83.
2012: Johannes Vermehren; Stefan Zeuzem; Simone Susser; Regina Allwinn; Annemarie Berger; Kai-Henrik Peiffer; Dany Perner; Christoph Sarrazin
Clinical utility of the ARCHITECT HCV Ag assay for early treatment monitoring in patients with chronic hepatitis C genotype 1 infection.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2012;55(1):17-22.
2012: Johannes Vermehren; Christoph Sarrazin
The role of resistance in HCV treatment.
Best practice & research. Clinical gastroenterology 2012;26(4):487-503.
2012: M Biermer; A Brodzinski; B Fülöp; R Heyne; K Keller; Christoph Sarrazin; B Schlosser; Florian van Bommel; Thomas Berg
High-dose silibinin rescue treatment for HCV-infected patients showing suboptimal virologic response to standard combination therapy.
Journal of viral hepatitis 2012;19(8):547-53.
2012: Thomas von Hahn; Heiner Wedemeyer; Ahmed Abdelaziz; Thomas Berg; Nabila Hamdi; Behya Karavul; Michael P Manns; Tobias Müller; Stephanie Pfaender; Thomas Pietschmann; Andrej Potthoff; Christoph Sarrazin; Cordelia Schiene-Fischer; Eike Steinmann; Christian P Strassburg; Eric Trépo; Nguyen Dinh Van; Sandra Ciesek
Hepatocytes that express variants of cyclophilin A are resistant to HCV infection and replication.
Gastroenterology 2012;143(2):439-47.e1.
2012: Dominik Bergis; Cristoph Betz; Mireen Friedrich-Rust; Christoph Sarrazin; Stefan Zeuzem; Jörg Bojunga
Treatment of Amanita phalloides intoxication by fractionated plasma separation and adsorption (Prometheus®).
Journal of gastrointestinal and liver diseases : JGLD 2012;21(2):171-6.
2012: Janett Fischer; Balazs Fülöp; Jacob George; Pascal Migaud; Tobias Müller; Christoph Sarrazin; Markus Scholz; Eckart Schott; Graeme J Stewart; Vijayaprakash Suppiah; Simone Susser; Florian van Bommel; Heiko Witt; Stephan Böhm; David R Booth; Annika Brodzinski; Thomas Berg
Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection.
Hepatology (Baltimore, Md.) 2012;55(6):1700-10.
2012: Johannes Vermehren; Stefan Zeuzem; Olga Zimmermann; Jörg Bojunga; Eva Herrmann; Wolf Peter Hofmann; Andreas Polta; Thierry Poynard; Christoph Sarrazin; Mireen Friedrich-Rust
Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
Liver international : official journal of the International Association for the Study of the Liver 2012;32(5):852-8.
2012: Johannes Vermehren; Felix Walcher; Stefan Zeuzem; Annemarie Berger; Diana Domke; Sandra Elanjimattom; Norbert Haas; Karin Hensel-Wiegel; Gudrun Hintereder; Ralf Lehmann; Martin Möckel; Christian Müller; Christoph Sarrazin; Beate Schlosser; Rudolf Tauber; Thomas Berg
High prevalence of anti-HCV antibodies in two metropolitan emergency departments in Germany: a prospective screening analysis of 28,809 patients.
PloS one 2012;7(7):e41206.
2012: Christian M Lange; Raffaele Malinverni; Darius Moradpour; Tobias Müller; Francesco Negro; Stephan Regenass; Christoph Sarrazin; Stefan Zeuzem; Klaus Badenhoop; Thomas Berg; Stephanie Bibert; Pierre-Yves Bochud; Jörg Bojunga; Philippe Burgisser; Andreas Cerny; Jean-Francois Dufour; Andreas Geier; Tilman J Gerlach; Markus H Heim; Zoltan Kutalik
A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C.
PloS one 2012;7(7):e40159.
2012: Roman Müllenbach; Christoph Sarrazin; Susanne N Weber; Vincent Zimmer; Marcin Krawczyk; Frank Lammert; Frank Grünhage
A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population.
BMC gastroenterology 2012;12():63.
2012: Johannes Vermehren; Stefan Zeuzem; Amina Carlebach; Nicole Forestier; Mireen Friedrich-Rust; Peter Gute; Eva Herrmann; Gaby Knecht; Thomas Lutz; Axel Mueller; Thierry Poynard; Christoph Sarrazin; Annika Vermehren; Wolf Peter Hofmann
Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
BMC gastroenterology 2012;12():27.
2012: Johannes Vermehren; Sabine Wicker; Stefan Zeuzem; Annemarie Berger; Jörn Lötsch; Christoph Sarrazin; Simone Susser; Alexandra Doehring
A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers.
PloS one 2012;7(3):e32605.
2012: Martin Walter Welker; Stefan Zeuzem; Eva Herrmann; Yolanda Martinez; Albrecht Piiper; David Reichert; Christoph Sarrazin; Simone Susser; Bernd Kronenberger
Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity.
PloS one 2012;7(2):e30796.
2012: Christoph Sarrazin; Stefan Zeuzem; Christophe Hézode; Jean-Michel Pawlotsky
Antiviral strategies in hepatitis C virus infection.
Journal of hepatology 2012;56 Suppl 1():S88-100.
2012: N Hamdi; Christoph Sarrazin; W El-Akel; M El-Serafy; Gamal Esmat; Ahmed Abdelaziz
Transcriptional response of MxA, PKR and SOCS3 to interferon-based therapy in HCV genotype 4-infected patients and contribution of p53 to host antiviral response.
Intervirology 2012;55(3):210-8.
2011: Johannes Wiegand; Stephan Böhm; Peter Buggisch; Tilman Gerlach; Holger Hinrichsen; Hartwig Klinker; Bernd Möller; Konrad Neumann; Jens Rasenack; Christoph Sarrazin; Ulrich Spengler; Gerlinde Teuber; Viola Weich; Thomas Berg
Importance of minimal residual viremia for relapse prediction in patients with chronic hepatitis C genotype 1 infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;53(11):1111-4.
2011: Simone Susser; Johannes Vermehren; Martin Walter Welker; Stefan Zeuzem; Nicole Forestier; Caterina Füller; Natalia Grigorian; Dany Perner; Christoph Sarrazin
Analysis of long-term persistence of resistance mutations within the hepatitis C virus NS3 protease after treatment with telaprevir or boceprevir.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011;52(4):321-7.
2011: Harald Farnik; Eva Herrmann; Wolf Peter Hofmann; Christian Markus Lange; Christoph Sarrazin; Jörg Trojan; Martin Walter Welker; Stefan Zeuzem; Regina Allwinn; Annemarie Berger; Bernd Kronenberger
Nucleos(t)ide analogue treatment reduces apoptotic activity in patients with chronic hepatitis B.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011;52(3):204-9.
2011: J G Albert; M Elhendawy; Mireen Friedrich-Rust; J Trojan; S Zeuzem; Christoph Sarrazin
Peroral cholangioscopy for diagnosis and therapy of biliary tract disease using an ultra-slim gastroscope.
Endoscopy 2011;43(11):1004-9.
2011: Christian M Lange; Henk W Reesink; Janke Schinkel; Simone Susser; Stefan Zeuzem; Eva Herrmann; Ursula Karey; Tara L Kieffer; Ann D Kwong; Christoph Sarrazin
HVR-1 heterogeneity during treatment with telaprevir with or without pegylated interferon alfa-2a.
Scandinavian journal of gastroenterology 2011;46(11):1362-8.
2011: Christoph Sarrazin; Ewert Schulte-Frohlinde; Susanne Schwendy; Gerlinde Teuber; Robert Thimme; Stefan Zeuzem; Wulf O Boecher; Peter Buggisch; Nektarios Dikopoulos; Jens Encke; Tobias Goeser; Eva Herrmann; Hartwig Klinker; Bernd Möller; Renate Prinzing; Thomas Berg
Improved responses to pegylated interferon alfa-2b and ribavirin by individualizing treatment for 24-72 weeks.
Gastroenterology 2011;141(5):1656-64.
2011: Johannes Vermehren; Joseph D Yao; Ming-Lung Yu; George Schneider; Christopher Anderson; Rasa Bertuzis; Alexander Monto; Christoph Sarrazin
Multi-center evaluation of the Abbott RealTime HCV assay for monitoring patients undergoing antiviral therapy for chronic hepatitis C.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011;52(2):133-7.
2011: Johannes Vermehren; Stefan Zeuzem; Heike Zitzer; Diana Thamke; Ahmed Abdelaziz; Giuseppe Colucci; Peter Gohl; Nabila Hamdi; Ursula Karey; Christoph Sarrazin
Development of a second version of the Cobas AmpliPrep/Cobas TaqMan hepatitis C virus quantitative test with improved genotype inclusivity.
Journal of clinical microbiology 2011;49(9):3309-15.
2011: Verena Bihrer; Nicole Forestier; Mireen Friedrich-Rust; Jörg Haupenthal; Eva Herrmann; Bernd Kronenberger; Jan Peveling-Oberhag; Heinfried H Radeke; Christoph Sarrazin; Ying Shi; Oliver Waidmann; Stefan Zeuzem; Albrecht Piiper
Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection.
The American journal of gastroenterology 2011;106(9):1663-9.
2011: Sandra Ciesek; Nabila Hamdi; Sylvana Henschen; Michael P Manns; Thomas Pietschmann; Christoph Sarrazin; Christian P Strassburg; Ilka Wappler; Heiner Wedemeyer; Sandra Westhaus; Melanie Wicht; Ahmed Abdelaziz; Thomas von Hahn
Impact of intra- and interspecies variation of occludin on its function as coreceptor for authentic hepatitis C virus particles.
Journal of virology 2011;85(15):7613-21.
2011: Christian M Lange; Hans-Anton Lehr; Jörn Lötsch; Christian Moench; Darius Moradpour; Beat Müllhaupt; Manuel Pascual; Christoph Sarrazin; Ying Shi; Stefan Zeuzem; Anca T Antonino; Wolf Otto Bechstein; Stephanie Bibert; Pierre-Yves Bochud; Alexandra Doehring; Harald Farnik; Martin-Leo Hansmann; Wolf Peter Hofmann
Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection.
Journal of hepatology 2011;55(2):322-7.
2011: Johannes Vermehren; Christoph Sarrazin
New hepatitis C therapies in clinical development.
European journal of medical research 2011;16(7):303-14.
2011: Markus Cornberg; K Dathe; M M Dollinger; Andreas Erhardt; W H Gerlich; W Jilg; I B Kopp; Michael P Manns; J Petersen; U Protzer; Christoph Sarrazin; Peter Schirmacher; Heiner Wedemeyer; S Wirth; Stefan Zeuzem; Thomas Berg
[Prophylaxis, diagnosis and therapy of hepatitis B virus infection - the German guideline].
Zeitschrift für Gastroenterologie 2011;49(7):871-930.
2011: Martin Walter Welker; Stefan Zeuzem; Eva Herrmann; Wolf Peter Hofmann; Christian Markus Lange; Christoph Sarrazin; Bernd Kronenberger
CD81 expression for discrimination between sustained virologic response and relapse in patients with chronic hepatitis C.
Scandinavian journal of gastroenterology 2011;46(7-8):973-80.
2011: Georg Dultz; Alireza Azizi; Bernd Kronenberger; Ulrike Mihm; Christoph Sarrazin; Ulrike Sarrazin; Thomas J Vogl; Stefan Zeuzem; Wolf Peter Hofmann
Portal vein thrombosis as complication of romiplostim treatment in a cirrhotic patient with hepatitis C-associated immune thrombocytopenic purpura.
Journal of hepatology 2011;55(1):229-32.
2011: Verena Schlaphoff; Sebastian Lunemann; Pothakamuri Venkata Suneetha; Jerzy Jaroszewicz; Jan Grabowski; Julia Dietz; Fabian Helfritz; Hueseyin Bektas; Christoph Sarrazin; Michael Peter Manns; Markus Cornberg; Heiner Wedemeyer
Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.
PLoS pathogens 2011;7(5):e1002045.
2011: Alexandra Doehring; Wolf Peter Hofmann; Christina Schlecker; Stefan Zeuzem; Christoph Sarrazin; Thomas Berg; Tobias Müller; Eva Herrmann; Gerd Geisslinger; Jörn Lötsch
Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy: protection against anemia in patients with chronic hepatitis C.
Pharmacogenetics and genomics 2011;21(5):289-96.
2011: Christian Markus Lange; Jörg Bojunga; Elizabeth Ramos Lopez; Michael von Wagner; Angela Hassler; Johannes Vermehren; Eva Herrmann; Klaus Badenhoop; Stefan Zeuzem; Christoph Sarrazin
Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy.
Journal of hepatology 2011;54(5):887-93.
2011: Christoph Sarrazin; Simone Susser; Alexandra Doehring; Christian Markus Lange; Tobias Müller; Christina Schlecker; Eva Herrmann; Jörn Lötsch; Thomas Berg
Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients.
Journal of hepatology 2011;54(3):415-21.
2011: Martin Walter Welker; Christoph Welsch; D Ochs; W P Hofmann; Eva Herrmann; Albrecht Piiper; Rolf W Hartmann; Stefan Zeuzem; Christoph Sarrazin; Bernd Kronenberger
Comparison of envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates.
Journal of viral hepatitis 2011;18(3):181-92.
2011: Verena Bihrer; Nicole Forestier; Mireen Friedrich-Rust; Jörg Haupenthal; Bernd Kronenberger; Jan Peveling-Oberhag; Andreas Polta; Heinfried H Radeke; Christoph Sarrazin; Ying Shi; Simone Susser; Jörg Trojan; Michael von Wagner; Oliver Waidmann; Martin Walter Welker; Stefan Zeuzem; Albrecht Piiper
Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma.
PloS one 2011;6(10):e26971.
2011: Wolf Peter Hofmann; Ursel Karey; Jörn Lötsch; Ulrike Mihm; Carola Osbahr; Christoph Sarrazin; Simone Susser; Christoph Welsch; Stefan Zeuzem; Tje Lin Chung; Eva Herrmann
Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir.
Antiviral therapy 2011;16(5):695-704.
2011: Philipp de Leuw; Christoph Sarrazin; Stefan Zeuzem
How to use virological tools for the optimal management of chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver 2011;31 Suppl 1():3-12.
2011: Christoph Sarrazin; Stefan Zeuzem
[Current Guidelines for treatment of hepatitis C. The eradication of HCV as a goal].
Pharmazie in unserer Zeit 2011;40(1):52-9.
2010: G Grammatikos; Christoph Sarrazin
[Chronic hepatitis C].
Deutsche medizinische Wochenschrift (1946) 2010;135(50):2525-34; quiz 2535-8.
2010: Christian Markus Lange; Kirsten Roomp; Anette Dragan; Jacob Nattermann; Monika Michalk; Ulrich Spengler; Viola Weich; Thomas Lengauer; Stefan Zeuzem; Thomas Berg; Christoph Sarrazin
HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection.
Journal of hepatology 2010;53(6):1022-8.
2010: Christian M Lange; Michael von Wagner; Jörg Bojunga; Thomas Berg; Harald Farnik; Angela Hassler; Christoph Sarrazin; Eva Herrmann; Stefan Zeuzem
Serum lipids in European chronic HCV genotype 1 patients during and after treatment with pegylated interferon-α-2a and ribavirin.
European journal of gastroenterology & hepatology 2010;22(11):1303-7.
2010: Harald Farnik; Christian M Lange; Christoph Sarrazin; Bernd Kronenberger; Stefan Zeuzem; Eva Herrmann
Meta-analysis shows extended therapy improves response of patients with chronic hepatitis C virus genotype 1 infection.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2010;8(10):884-90.
2010: J G Albert; F Ulrich; Stefan Zeuzem; Christoph Sarrazin
[Endoscopic-retrograde cholangiopancreatography in patients with surgical modification of anatomy].
Zeitschrift für Gastroenterologie 2010;48(8):839-49.
2010: Martin Walter Welker; Christoph Welsch; Aline Meyer; Iris Antes; Mario Albrecht; Nicole Forestier; Bernd Kronenberger; Thomas Lengauer; Albrecht Piiper; Stefan Zeuzem; Christoph Sarrazin
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper.
Protein science : a publication of the Protein Society 2010;19(7):1327-36.
2010: C M Lange; Christoph Sarrazin; Stefan Zeuzem
Review article: specifically targeted anti-viral therapy for hepatitis C - a new era in therapy.
Alimentary pharmacology & therapeutics 2010;32(1):14-28.
2010: Christoph Sarrazin; Mitchell L Shiffman; Stephanos J Hadziyannis; Amy Lin; Giuseppe Colucci; Hiroshi Ishida; Stefan Zeuzem
Definition of rapid virologic response with a highly sensitive real-time PCR-based HCV RNA assay in peginterferon alfa-2a plus ribavirin response-guided therapy.
Journal of hepatology 2010;52(6):832-8.
2010: Ulrike Mihm; Wolf Peter Hofmann; Christoph Welsch; A Polta; Thomas Lengauer; Stefan Zeuzem; Christoph Sarrazin; Eva Herrmann
Effect of ribavirin on the frequency of RNase L cleavage sites within the hepatitis C viral genome.
Journal of viral hepatitis 2010;17(3):217-21.
2010: Christoph Sarrazin; Thomas Berg; R S Ross; Peter Schirmacher; H Wedemeyer; U Neumann; H H Schmidt; Ulrich Spengler; S Wirth; H H Kessler; M Peck-Radosavljevic; P Ferenci; W Vogel; D Moradpour; M Heim; M Cornberg; U Protzer; Michael P Manns; W E Fleig; M M Dollinger; Stefan Zeuzem
[Prophylaxis, diagnosis and therapy of hepatitis C virus (HCV) infection: the German guidelines on the management of HCV infection].
Zeitschrift für Gastroenterologie 2010;48(2):289-351.
2010: Christoph Sarrazin; Stefan Zeuzem
Resistance to direct antiviral agents in patients with hepatitis C virus infection.
Gastroenterology 2010;138(2):447-62.
2010: Alexandra Doehring; Wolf Peter Hofmann; Christina Schlecker; Stefan Zeuzem; Simone Susser; Gerd Geisslinger; Christoph Sarrazin; Jörn Lötsch
Screening for IL28B gene variants identifies predictors of hepatitis C therapy success.
Antiviral therapy 2010;15(8):1099-106.
2010: Mireen Friedrich-Rust; William Rosenberg; Julie Parkes; Eva Herrmann; Stefan Zeuzem; Christoph Sarrazin
Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
BMC gastroenterology 2010;10():103.
2010: Florian van Bommel; Robert A de Man; Heiner Wedemeyer; Katja Deterding; Jörg Petersen; Peter Buggisch; Andreas Erhardt; Dietrich Hüppe; Kerstin Stein; Jörg Trojan; Christoph Sarrazin; Wulf O Böcher; Ulrich Spengler; Hermann E Wasmuth; Jurrien G P Reinders; Bernd Möller; Peter Rhode; Heinz-Hubert Feucht; Bertram Wiedenmann; Thomas Berg
Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues.
Hepatology (Baltimore, Md.) 2010;51(1):73-80.
2010: Mireen Friedrich-Rust; Cindy Müller; Anne Winckler; Susanne Kriener; Eva Herrmann; Julia Holtmeier; Thierry Poynard; Thomas J Vogl; Stefan Zeuzem; Renate Hammerstingl; Christoph Sarrazin
Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
Journal of clinical gastroenterology 2010;44(1):58-65.
2009: Christian M Lange; Jörg Bojunga; Wolf Peter Hofmann; Katrin Wunder; Ulrike Mihm; Stefan Zeuzem; Christoph Sarrazin
Severe lactic acidosis during treatment of chronic hepatitis B with entecavir in patients with impaired liver function.
Hepatology (Baltimore, Md.) 2009;50(6):2001-6.
2009: Harald Farnik; Juliane El-Duweik; Christoph Welsch; Christoph Sarrazin; Jörn Lötsch; Stefan Zeuzem; Gerd Geisslinger; Helmut Schmidt
Highly sensitive determination of HCV protease inhibitors boceprevir (SCH 503034) and telaprevir (VX 950) in human plasma by LC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(31):4001-6.
2009: Simone Susser; Christoph Welsch; Yalan Wang; Markus Zettler; Francisco S Domingues; Ursula Karey; Eric Hughes; Robert Ralston; Xiao Tong; Eva Herrmann; Stefan Zeuzem; Christoph Sarrazin
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
Hepatology (Baltimore, Md.) 2009;50(6):1709-18.
2009: Mireen Friedrich-Rust; A Schwarz; M Ong; V Dries; P Schirmacher; Eva Herrmann; P Samaras; Jörg Bojunga; Rainer M Bohle; Stefan Zeuzem; Christoph Sarrazin
Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
Ultraschall in der Medizin (Stuttgart, Germany : 1980) 2009;30(5):478-84.
2009: Andreas Mas-Marques; Tobias Mueller; Justus Welke; Stefan Taube; Christoph Sarrazin; Manfred Wiese; Juliane Halangk; Heiko Witt; Golo Ahlenstiel; Ulrich Spengler; Uwe Goebel; Eckart Schott; Viola Weich; Beate Schlosser; Hermann E Wasmuth; Frank Lammert; Thomas Berg; Eckart Schreier
Low-density lipoprotein receptor variants are associated with spontaneous and treatment-induced recovery from hepatitis C virus infection.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2009;9(5):847-52.
2009: Mireen Friedrich-Rust; Katrin Wunder; Susanne Kriener; Fariba Sotoudeh; Swantje Richter; Joerg Bojunga; Eva Herrmann; Thierry Poynard; Christoph F Dietrich; Johannes Vermehren; Stefan Zeuzem; Christoph Sarrazin
Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography.
Radiology 2009;252(2):595-604.
2009: Thomas Berg; Viola Weich; Gerlinde Teuber; Hartwig Klinker; Bernd Möller; Jens Rasenack; Holger Hinrichsen; Tilman Gerlach; Ulrich Spengler; Peter Buggisch; Heike Balk; Myrga Zankel; Konrad Neumann; Christoph Sarrazin; Stefan Zeuzem
Individualized treatment strategy according to early viral kinetics in hepatitis C virus type 1-infected patients.
Hepatology (Baltimore, Md.) 2009;50(2):369-77.
2009: Juliane Halangk; Thomas Berg; Konrad Neumann; Christoph Sarrazin; Holger Hinrichsen; Carolin Fitz; Gero Puhl; Tobias Mueller; Peter Neuhaus; Bertram Wiedenmann; Heiko Witt
Evaluation of angiotensinogen c.1-44G>A and p.M268T variants as risk factors for fibrosis progression in chronic hepatitis C and liver diseases of various etiologies.
Genetic testing and molecular biomarkers 2009;13(3):407-14.
2009: Stefan Zeuzem; Thomas Berg; B Moeller; H Hinrichsen; S Mauss; H Wedemeyer; Christoph Sarrazin; D Hueppe; E Zehnter; M P Manns
Expert opinion on the treatment of patients with chronic hepatitis C.
Journal of viral hepatitis 2009;16(2):75-90.
2009: Ulrike Mihm; Oliver Ackermann; Christoph Welsch; Eva Herrmann; Wolf Peter Hofmann; Natalia Grigorian; Martin Walter Welker; Thomas Lengauer; Stefan Zeuzem; Christoph Sarrazin
Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C.
Journal of hepatology 2009;50(1):49-58.
2008: Wolf Peter Hofmann; Eva Herrmann; Christoph Sarrazin; Stefan Zeuzem
Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanisms.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(10):1332-43.
2008: Mireen Friedrich-Rust; Guenther Schneider; Rainer M Bohle; Eva Herrmann; Christoph Sarrazin; Stefan Zeuzem; Joerg Bojunga
Contrast-enhanced sonography of adrenal masses: differentiation of adenomas and nonadenomatous lesions.
AJR. American journal of roentgenology 2008;191(6):1852-60.
2008: Johannes Vermehren; Annika Kau; Barbara C Gärtner; Reinhild Göbel; Stefan Zeuzem; Christoph Sarrazin
Differences between two real-time PCR-based hepatitis C virus (HCV) assays (RealTime HCV and Cobas AmpliPrep/Cobas TaqMan) and one signal amplification assay (Versant HCV RNA 3.0) for RNA detection and quantification.
Journal of clinical microbiology 2008;46(12):3880-91.
2008: W P Hofmann; Bernd Kronenberger; Jörg Bojunga; B Stamm; Eva Herrmann; A Bücker; U Mihm; Michael von Wagner; Stefan Zeuzem; Christoph Sarrazin
Prospective study of bone mineral density and metabolism in patients with chronic hepatitis C during pegylated interferon alpha and ribavirin therapy.
Journal of viral hepatitis 2008;15(11):790-6.
2008: Annika Kau; Johannes Vermehren; Christoph Sarrazin
Treatment predictors of a sustained virologic response in hepatitis B and C.
Journal of hepatology 2008;49(4):634-51.
2008: Christoph Sarrazin; Anette Dragan; Barbara C Gärtner; Michael S Forman; Stella Traver; Stefan Zeuzem; Alexandra Valsamakis
Evaluation of an automated, highly sensitive, real-time PCR-based assay (COBAS Ampliprep/COBAS TaqMan) for quantification of HCV RNA.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2008;43(2):162-8.
2008: Juliane Halangk; Christoph Sarrazin; Konrad Neumann; Gero Puhl; Tobias Mueller; Gerlinde Teuber; Hartwig Klinker; Holger Hinrichsen; Peter Buggisch; Olfert Landt; Viola Weich; Alexandra Bergk; Bertram Wiedenmann; Peter Neuhaus; Thomas Berg; Heiko Witt
Evaluation of complement factor 5 variants as genetic risk factors for the development of advanced fibrosis in chronic hepatitis C infection.
Journal of hepatology 2008;49(3):339-45.
2008: P Fytili; G N Dalekos; V Schlaphoff; P V Suneetha; Christoph Sarrazin; W Zauner; K Zachou; T Berg; Michael P Manns; Christoph S Klade; Markus Cornberg; Heiner Wedemeyer
Cross-genotype-reactivity of the immunodominant HCV CD8 T-cell epitope NS3-1073.
Vaccine 2008;26(31):3818-26.
2008: Mireen Friedrich-Rust; Mei-Fang Ong; Swantje Martens; Christoph Sarrazin; Joerg Bojunga; Stefan Zeuzem; Eva Herrmann
Performance of transient elastography for the staging of liver fibrosis: a meta-analysis.
Gastroenterology 2008;134(4):960-74.
2008: Mireen Friedrich-Rust; Constanze Koch; Axel Rentzsch; Christoph Sarrazin; Peter Schwarz; Eva Herrmann; Angelika Lindinger; Ulrike Sarrazin; Thierry Poynard; Hans-Joachim Schäfers; Stefan Zeuzem; Hashim Abdul-Khaliq
Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
The Journal of thoracic and cardiovascular surgery 2008;135(3):560-7.
2008: Mireen Friedrich-Rust; Eva Herrmann; Stefan Zeuzem; Christoph Sarrazin
Reply to Real-time elastography in the assessment of liver fibrosis.
AJR. American journal of roentgenology 2008;190(2):W164.
2007: Wolf Peter Hofmann; Christoph Welsch; Yoshitomo Takahashi; Hiroaki Miyajima; Ulrike Mihm; Christoph Krick; Stefan Zeuzem; Christoph Sarrazin
Identification and in silico characterization of a novel compound heterozygosity associated with hereditary aceruloplasminemia.
Scandinavian journal of gastroenterology 2007;42(9):1088-94.
2007: Tara L Kieffer; Christoph Sarrazin; Janice Miller; Martin Walter Welker; Nicole Forestier; Henk W Reesink; Ann D Kwong; Stefan Zeuzem
Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients.
Hepatology (Baltimore, Md.) 2007;46(3):631-9.
2007: Christoph Welsch; Mario Albrecht; Jochen Maydt; Eva Herrmann; Martin Walter Welker; Christoph Sarrazin; Axel J Scheidig; Thomas Lengauer; Stefan Zeuzem
Structural and functional comparison of the non-structural protein 4B in flaviviridae.
Journal of molecular graphics & modelling 2007;26(2):546-57.
2007: Mireen Friedrich-Rust; Nicole Forestier; Christoph Sarrazin; Henk W Reesink; Eva Herrmann; Stefan Zeuzem
Ultrasound evaluation of perihepatic lymph nodes during antiviral therapy with the protease inhibitor telaprevir (VX-950) in patients with chronic hepatitis C infection.
Ultrasound in medicine & biology 2007;33(9):1362-7.
2007: Wolf Peter Hofmann; B Fernandez; Eva Herrmann; Christoph Welsch; Ulrike Mihm; Bernd Kronenberger; G Feldmann; U Spengler; Stefan Zeuzem; Christoph Sarrazin
Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases.
Journal of viral hepatitis 2007;14(7):484-91.
2007: Christoph Sarrazin; Tara L Kieffer; Doug Bartels; Brian L Hanzelka; Ute Müh; Martin Walter Welker; Dennis Wincheringer; Yi Zhou; Hui-May Chu; Chao Lin; Christine J Weegink; Henk W Reesink; Stefan Zeuzem; Ann D Kwong
Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir.
Gastroenterology 2007;132(5):1767-77.
2007: Martin Walter Welker; Wolf Peter Hofmann; Christoph Welsch; Michael von Wagner; Eva Herrmann; Thomas Lengauer; Stefan Zeuzem; Christoph Sarrazin
Correlation of amino acid variations within nonstructural 4B protein with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients.
Journal of viral hepatitis 2007;14(5):338-49.
2007: Christoph Sarrazin; Regine Rouzier; Frank Wagner; Nicole Forestier; Dominique Larrey; Samir K Gupta; Musaddeq Hussain; Amrik Shah; David L Cutler; Jenny Zhang; Stefan Zeuzem
SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders.
Gastroenterology 2007;132(4):1270-8.
2007: Mireen Friedrich-Rust; Stefan Zeuzem; Christoph Sarrazin
Current therapy for hepatitis C.
International journal of colorectal disease 2007;22(4):341-9.
2007: Wolf Peter Hofmann; Andreas Polta; Eva Herrmann; Ulrike Mihm; Bernd Kronenberger; Tanja Sonntag; Volker Lohmann; Barbara Schönberger; Stefan Zeuzem; Christoph Sarrazin
Mutagenic effect of ribavirin on hepatitis C nonstructural 5B quasispecies in vitro and during antiviral therapy.
Gastroenterology 2007;132(3):921-30.
2007: Mireen Friedrich-Rust; Mei-Fang Ong; Eva Herrmann; Volker Dries; Panagiotis Samaras; Stefan Zeuzem; Christoph Sarrazin
Real-time elastography for noninvasive assessment of liver fibrosis in chronic viral hepatitis.
AJR. American journal of roentgenology 2007;188(3):758-64.
2007: Ankur Goyal; Wolf Peter Hofmann; Eva Hermann; Stella Traver; Syed Hissar; Naveen Arora; Hubert E Blum; Stefan Zeuzem; Christoph Sarrazin; Shiv K Sarin
The hepatitis C virus NS5A protein and response to interferon alpha: mutational analyses in patients with chronic HCV genotype 3a infection from India.
Medical microbiology and immunology 2007;196(1):11-21.
2007: Bernd Kronenberger; Stefan Zeuzem; Christoph Sarrazin; Ulrike Mihm; Michael von Wagner; Wolf Peter Hofmann; Albrecht Piiper; Eva Herrmann
Dynamics of apoptotic activity during antiviral treatment of patients with chronic hepatitis C.
Antiviral therapy 2007;12(5):779-87.
2007: Johannes Wiegand; Markus Cornberg; Nuray Aslan; Verena Schlaphoff; Christoph Sarrazin; Anne Kubitschke; Peter Buggisch; Ayse Ciner; Elmar Jaeckel; Michael P Manns; Heiner Wedemeyer
Fate and function of hepatitis-C-virus-specific T-cells during peginterferon-alpha2b therapy for acute hepatitis C.
Antiviral therapy 2007;12(3):303-16.
2007: Anette Wohnsland; Wolf Peter Hofmann; Christoph Sarrazin
Viral determinants of resistance to treatment in patients with hepatitis C.
Clinical microbiology reviews 2007;20(1):23-38.
2007: Arne Schneider; Wolfgang F Caspary; Rebecca Saich; Christoph F Dietrich; Christoph Sarrazin; Wilhelm Kuker; Barbara Braden
13C-methacetin breath test shortened: 2-point-measurements after 15 minutes reliably indicate the presence of liver cirrhosis.
Journal of clinical gastroenterology 2007;41(1):33-7.
2007: Anne Kubitschke; M J Bahr; Nuray Aslan; C Bader; Hans L Tillmann; Christoph Sarrazin; Tim F Greten; Johannes Wiegand; Michael P Manns; Heiner Wedemeyer
Induction of hepatitis C virus (HCV)-specific T cells by needle stick injury in the absence of HCV-viraemia.
European journal of clinical investigation 2007;37(1):54-64.
2006: Michael von Wagner; J-H Lee; Bernd Kronenberger; R Friedl; Christoph Sarrazin; Gerlinde Teuber; Eva Herrmann; Stefan Zeuzem
Impaired health-related quality of life in patients with chronic hepatitis C and persistently normal aminotransferase levels.
Journal of viral hepatitis 2006;13(12):828-34.
2006: Jorg Bojunga; Christoph Sarrazin; Georg Hess; Stefan Zeuzem
Elevated plasma levels of N-terminal pro-brain natriuretic peptide in patients with chronic hepatitis C during interferon-based antiviral therapy.
World journal of gastroenterology : WJG 2006;12(36):5875-7.
2006: Florian van Bommel; Bernhard Zöllner; Christoph Sarrazin; Ulrich Spengler; Dietrich Hüppe; Bernd Möller; Heinz-Hubert Feucht; Bertram Wiedenmann; Thomas Berg
Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy.
Hepatology (Baltimore, Md.) 2006;44(2):318-25.
2006: Bernd Kronenberger; Eva Herrmann; Wolf Peter Hofmann; Heiner Wedemeyer; Martina Sester; Ulrike Mihm; Temam Ghaliai; Stefan Zeuzem; Christoph Sarrazin
Dynamics of CD81 expression on lymphocyte subsets during interferon-alpha-based antiviral treatment of patients with chronic hepatitis C.
Journal of leukocyte biology 2006;80(2):298-308.
2006: Ulrike Mihm; Eva Herrmann; Christoph Sarrazin; Stefan Zeuzem
Review article: predicting response in hepatitis C virus therapy.
Alimentary pharmacology & therapeutics 2006;23(8):1043-54.
2006: Thomas Berg; Michael von Wagner; Samer Nasser; Christoph Sarrazin; Tobias Heintges; Tilman Gerlach; Peter Buggisch; Tobias Goeser; Jens Rasenack; Gerd R Pape; Wolfgang E Schmidt; Birgit Kallinowski; Hartwig Klinker; Ulrich Spengler; Peter Martus; Ulrich Alshuth; Stefan Zeuzem
Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin.
Gastroenterology 2006;130(4):1086-97.
2006: Christoph Sarrazin; Barbara C Gärtner; Dorothea Sizmann; Rainer Babiel; Ulrike Mihm; Wolf Peter Hofmann; Michael von Wagner; Stefan Zeuzem
Comparison of conventional PCR with real-time PCR and branched DNA-based assays for hepatitis C virus RNA quantification and clinical significance for genotypes 1 to 5.
Journal of clinical microbiology 2006;44(3):729-37.
2006: Ulrike Mihm; Natalia Grigorian; Christoph Welsch; Eva Herrmann; Bernd Kronenberger; Gerlinde Teuber; Michael von Wagner; Wolf Peter Hofmann; Mario Albrecht; Thomas Lengauer; Stefan Zeuzem; Christoph Sarrazin
Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C.
Antiviral therapy 2006;11(4):507-19.
2006: Eva Herrmann; Stefan Zeuzem; Christoph Sarrazin; Holger Hinrichsen; Yves Benhamou; Michael P Manns; Markus Reiser; Henk W Reesink; José L Calleja; Xavier Forns; Gerhard G Steinmann; Gerhard Nehmiz
Viral kinetics in patients with chronic hepatitis C treated with the serine protease inhibitor BILN 2061.
Antiviral therapy 2006;11(3):371-6.
2006: Wolf Peter Hofmann; H Bock; C Weber; W Tacke; R Pfaff; R Kihn; G Moog; H U Kellner; M Schöfer; B Frick; P Berg; A Rambow; Mireen Friedrich-Rust; Eva Herrmann; Christoph Sarrazin; Stefan Zeuzem
[Effectiveness of antiviral therapy in patients with chronic hepatitis C treated by private practice gastroenterologists].
Zeitschrift für Gastroenterologie 2006;44(1):25-31.
2005: Christoph Sarrazin; Ulrike Mihm; Eva Herrmann; Christoph Welsch; Mario Albrecht; Ulrike Sarrazin; Stella Traver; Thomas Lengauer; Stefan Zeuzem
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection.
The Journal of infectious diseases 2005;192(10):1710-9.
2005: Christoph Sarrazin; Thomas Berg; Viola Weich; Tobias Mueller; Ulrich H Frey; Stefan Zeuzem; Guido Gerken; Michael Roggendorf; Winfried Siffert
GNB3 C825T polymorphism and response to interferon-alfa/ribavirin treatment in patients with hepatitis C virus genotype 1 (HCV-1) infection.
Journal of hepatology 2005;43(3):388-93.
2005: Ulrike Mihm; Barbara C Gärtner; Dominik Faust; Wolf Peter Hofmann; Christoph Sarrazin; Stefan Zeuzem; Eva Herrmann
Viral kinetics in patients with lamivudine-resistant hepatitis B during adefovir-lamivudine combination therapy.
Journal of hepatology 2005;43(2):217-24.
2005: Bernd Kronenberger; M Wagner; Eva Herrmann; Ulrike Mihm; Albrecht Piiper; Christoph Sarrazin; Stefan Zeuzem
Apoptotic cytokeratin 18 neoepitopes in serum of patients with chronic hepatitis C.
Journal of viral hepatitis 2005;12(3):307-14.
2005: Wolf Peter Hofmann; Volker Dries; Eva Herrmann; Barbara C Gärtner; Stefan Zeuzem; Christoph Sarrazin
Comparison of transcription mediated amplification (TMA) and reverse transcription polymerase chain reaction (RT-PCR) for detection of hepatitis C virus RNA in liver tissue.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;32(4):289-93.
2005: Ulrike Mihm; Wolf Peter Hofmann; Bernd Kronenberger; Michael von Wagner; Stefan Zeuzem; Christoph Sarrazin
Highly sensitive hepatitis C virus RNA detection assays for decision of treatment (dis)continuation in patients with chronic hepatitis C.
Journal of hepatology 2005;42(4):605-6.
2005: Wolf Peter Hofmann; Stefan Zeuzem; Christoph Sarrazin
Hepatitis C virus-related resistance mechanisms to interferon alpha-based antiviral therapy.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;32(2):86-91.
2005: B Braden; Dominik Faust; Ulrike Sarrazin; Stefan Zeuzem; C F Dietrich; Wolfgang F Caspary; Christoph Sarrazin
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Alimentary pharmacology & therapeutics 2005;21(2):179-85.
2004: Tobias Mueller; Andreas Mas-Marques; Christoph Sarrazin; Manfred Wiese; Juliane Halangk; Heiko Witt; Golo Ahlenstiel; Ulrich Spengler; Uwe Goebel; Bertram Wiedenmann; Eckart Schreier; Thomas Berg
Influence of interleukin 12B (IL12B) polymorphisms on spontaneous and treatment-induced recovery from hepatitis C virus infection.
Journal of hepatology 2004;41(4):652-8.
2004: Wolf Peter Hofmann; Eva Herrmann; Bernd Kronenberger; Christian Merkwirth; Christoph Welsch; Thomas Lengauer; Stefan Zeuzem; Christoph Sarrazin
Association of HCV-related mixed cryoglobulinemia with specific mutational pattern of the HCV E2 protein and CD81 expression on peripheral B lymphocytes.
Blood 2004;104(4):1228-9.
2004: Bernd Kronenberger; Christoph Sarrazin; Wolf Peter Hofmann; Michael von Wagner; Eva Herrmann; Christoph Welsch; Robert Elez; Brigitte Rüster; Albrecht Piiper; Stefan Zeuzem
Mutations in the putative HCV-E2 CD81 binding regions and correlation with cell surface CD81 expression.
Journal of viral hepatitis 2004;11(4):310-8.
2004: Stefan Zeuzem; Rolf Hultcrantz; Marc Bourliere; Tobias Goeser; Patrick Marcellin; Jose Sanchez-Tapias; Christoph Sarrazin; Joann Harvey; Clifford Brass; Janice Albrecht
Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3.
Journal of hepatology 2004;40(6):993-9.
2004: Eva Herrmann; Christoph Sarrazin
[Hepatitis C-virus --virus kinetics and resistance mechanisms].
Zeitschrift für Gastroenterologie 2004;42(5):387-96.
2004: Thomas Berg; Christoph Sarrazin; Holger Hinrichsen; Peter Buggisch; Tilman Gerlach; Reinhart Zachoval; Stefan Zeuzem
Does noninvasive staging of fibrosis challenge liver biopsy as a gold standard in chronic hepatitis C?
Hepatology (Baltimore, Md.) 2004;39(5):1456-7; author reply 1457-8.
2004: Ulrike Mihm; Eva Herrmann; Ulrike Sarrazin; Michael von Wagner; Bernd Kronenberger; Stefan Zeuzem; Christoph Sarrazin
Association of serum interleukin-8 with virologic response to antiviral therapy in patients with chronic hepatitis C.
Journal of hepatology 2004;40(5):845-52.
2004: Ulrike Sarrazin; R Brodt; Christoph Sarrazin; Stefan Zeuzem
[Postexposure prevention after occupational exposure to HBV, HCV and HIV].
Der Unfallchirurg 2004;107(2):129-142.
2004: Ulrike Sarrazin; R Brodt; Christoph Sarrazin; Stefan Zeuzem
[Post-exposure prevention after occupational exposure to HBV, HCV and HIV].
Der Orthopäde 2004;33(2):231-44.
2004: Ulrike Sarrazin; R Brodt; Christoph Sarrazin; Stefan Zeuzem
[Postexposure prophylaxis after occupational exposure to HBV, HCV and HIV].
Der Radiologe 2004;44(2):181-94.
2003: Tobias Mueller; Reinhard Gessner; Christoph Sarrazin; Carola Graf; Juliane Halangk; Heiko Witt; Eckart Köttgen; Bertram Wiedenmann; Thomas Berg
Apolipoprotein E4 allele is associated with poor treatment response in hepatitis C virus (HCV) genotype 1.
Hepatology (Baltimore, Md.) 2003;38(6):1592; author reply 1592-3.
2003: Ulrike Sarrazin; R Brodt; Christoph Sarrazin; Stefan Zeuzem
[Postexposure prevention after occupational exposure to HBV, HCV and HIV].
Der Urologe. Ausg. A 2003;42(11):1497-1510; quiz 1511-2.
2003: Michael von Wagner; J-H Lee; Brigitte Rüster; Bernd Kronenberger; Christoph Sarrazin; W K Roth; Stefan Zeuzem
Dynamics of hepatitis C virus quasispecies turnover during interferon-alpha treatment.
Journal of viral hepatitis 2003;10(6):413-22.
2003: Stefan Zeuzem; E Jenny Heathcote; Mitchell L Shiffman; Teresa L Wright; Vincent G Bain; Morris Sherman; S Victor Feinman; Michael W Fried; Jens Rasenack; Christoph Sarrazin; Donald M Jensen; Amy Lin; Joseph H Hoffman; Farhad Sedarati
Twelve weeks of follow-up is sufficient for the determination of sustained virologic response in patients treated with interferon alpha for chronic hepatitis C.
Journal of hepatology 2003;39(1):106-11.
2003: Wolf Peter Hofmann; Christoph Sarrazin; Bernd Kronenberger; Barbara Schönberger; Katharina Bruch; Stefan Zeuzem
Mutations within the CD81-binding sites and hypervariable region 2 of the envelope 2 protein: correlation with treatment response in hepatitis C virus-infected patients.
The Journal of infectious diseases 2003;187(6):982-7.
2003: Ulrike Mihm; Christoph Sarrazin; Eva Herrmann; Gerlinde Teuber; Michael von Wagner; Bernd Kronenberger; Stefan Zeuzem
Response predictors and results of a long-term treatment with lamivudine in patients with chronic hepatitis B.
Zeitschrift für Gastroenterologie 2003;41(3):249-54.
2003: Thomas Berg; Christoph Sarrazin; Eva Herrmann; Holger Hinrichsen; Tilman Gerlach; Reinhart Zachoval; Bertram Wiedenmann; Uwe Hopf; Stefan Zeuzem
Prediction of treatment outcome in patients with chronic hepatitis C: significance of baseline parameters and viral dynamics during therapy.
Hepatology (Baltimore, Md.) 2003;37(3):600-9.
2002: Christoph Sarrazin
Highly sensitive hepatitis C virus RNA detection methods: molecular backgrounds and clinical significance.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2002;25 Suppl 3():S23-9.
2002: Christoph Sarrazin; Eva Herrmann; Katharina Bruch; Stefan Zeuzem
Hepatitis C virus nonstructural 5A protein and interferon resistance: a new model for testing the reliability of mutational analyses.
Journal of virology 2002;76(21):11079-90.
2001: Christoph Sarrazin; M Bruckner; Eva Herrmann; Brigitte Rüster; Katharina Bruch; W Kurt Roth; Stefan Zeuzem
Quasispecies heterogeneity of the carboxy-terminal part of the E2 gene including the PePHD and sensitivity of hepatitis C virus 1b isolates to antiviral therapy.
Virology 2001;289(1):150-63.
2001: Christoph Sarrazin; D A Hendricks; Farhad Sedarati; Stefan Zeuzem
Assessment, by transcription-mediated amplification, of virologic response in patients with chronic hepatitis C virus treated with peginterferon alpha-2a.
Journal of clinical microbiology 2001;39(8):2850-5.
2000: Bernd Kronenberger; Brigitte Rüster; JH Lee; Christoph Sarrazin; W Kurt Roth; G Herrmann; Stefan Zeuzem
Hepatocellular proliferation in patients with chronic hepatitis C and persistently normal or abnormal aminotransferase levels.
Journal of hepatology 2000;33(4):640-7.
2000: Christoph Sarrazin; Gerlinde Teuber; R Kokka; H Rabenau; Stefan Zeuzem
Detection of residual hepatitis C virus RNA by transcription-mediated amplification in patients with complete virologic response according to polymerase chain reaction-based assays.
Hepatology (Baltimore, Md.) 2000;32(4 Pt 1):818-23.
2000: Christoph Sarrazin; Brigitte Rüster; JH Lee; Bernd Kronenberger; W Kurt Roth; Stefan Zeuzem
Prospective follow-up of patients with GBV-C/HGV infection: specific mutational patterns, clinical outcome, and genetic diversity.
Journal of medical virology 2000;62(2):191-8.
2000: Christoph Sarrazin; I Kornetzky; Brigitte Rüster; JH Lee; Bernd Kronenberger; Katharina Bruch; W Kurt Roth; Stefan Zeuzem
Mutations within the E2 and NS5A protein in patients infected with hepatitis C virus type 3a and correlation with treatment response.
Hepatology (Baltimore, Md.) 2000;31(6):1360-70.
2000: Christoph Sarrazin; Thomas Berg; JH Lee; Brigitte Rüster; Bernd Kronenberger; W Kurt Roth; Stefan Zeuzem
Mutations in the protein kinase-binding domain of the NS5A protein in patients infected with hepatitis C virus type 1a are associated with treatment response.
The Journal of infectious diseases 2000;181(2):432-41.
1999: Christoph Sarrazin; Stefan Zeuzem
[Interferon-alpha plus ribavirin combination therapy in chronic hepatitis C].
Zeitschrift für Gastroenterologie 1999;37(7):669-74.
1999: Christoph Sarrazin; Thomas Berg; JH Lee; Gerlinde Teuber; Christoph F Dietrich; W Kurt Roth; Stefan Zeuzem
Improved correlation between multiple mutations within the NS5A region and virological response in European patients chronically infected with hepatitis C virus type 1b undergoing combination therapy.
Journal of hepatology 1999;30(6):1004-13.
1998: Christoph Sarrazin; W Kurt Roth; Stefan Zeuzem
[GB virus-C/hepatitis G virus--discovery, epidemiology, diagnosis and clinical relevance].
Zeitschrift für Gastroenterologie 1998;36(11):997-1008.
1998: Christoph F Dietrich; J H Lee; R Gottschalk; G Herrmann; Christoph Sarrazin; Wolfgang F Caspary; Stefan Zeuzem
Hepatic and portal vein flow pattern in correlation with intrahepatic fat deposition and liver histology in patients with chronic hepatitis C.
AJR. American journal of roentgenology 1998;171(2):437-43.
1998: JH Lee; Michael von Wagner; W Kurt Roth; Gerlinde Teuber; Christoph Sarrazin; Stefan Zeuzem
Effect of ribavirin on virus load and quasispecies distribution in patients infected with hepatitis C virus.
Journal of hepatology 1998;29(1):29-35.
1997: Christoph Sarrazin; Stefan Zeuzem
[The clinical relevance of the GB virus C/hepatitis G virus].
Zeitschrift für Gastroenterologie 1997;35(11):1031-3.