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Alan Sartorelli

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
36
Rockwell, Sara
36
Shyam, Krishnamurthy
32
Penketh, Philip
20
Sokoloski, JA
18
Rappa, Germana
18
Lorico, Aurelio
17
Liu, Mao-Chin
17
Belcourt, Michael
14
Finch, Rick
14
Hodnick, William
12
Ishiguro, Kimiko
11
Tomasz, Maria
10
Li, Jianming
8
Luo, Mei-Zhen
8
Cory, Joseph

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Publications

TOP 3
Ishiguro Kimiko; Rice Anna M; Rice Kevin P; Sartorelli Alan C
Inhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1.
Ishiguro Kimiko; Shyam Krishnamurthy; Penketh Philip G; Sartorelli Alan C
Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein.
Baumann Raymond P; Penketh Philip G; Seow Helen A; Shyam Krishnamurthy; Sartorelli Alan C
Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells.

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All Publications

2009: Ishiguro Kimiko; Rice Anna M; Rice Kevin P; Sartorelli Alan C
Inhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1.
Leukemia research 2009;33(9):1249-54.
2008: Ishiguro Kimiko; Shyam Krishnamurthy; Penketh Philip G; Sartorelli Alan C
Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein.
Analytical biochemistry 2008;383(1):44-51.
2008: Baumann Raymond P; Penketh Philip G; Seow Helen A; Shyam Krishnamurthy; Sartorelli Alan C
Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells.
Radiation research 2008;170(5):651-60.
2008: Penketh Philip G; Baumann Raymond P; Ishiguro Kimiko; Shyam Krishnamurthy; Seow Helen A; Sartorelli Alan C
Lethality to leukemia cell lines of DNA interstrand cross-links generated by Cloretazine derived alkylating species.
Leukemia research 2008;32(10):1546-53.
2008: Bordonaro Michael; Lazarova Darina L; Sartorelli Alan C
Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk?
Cell cycle (Georgetown, Tex.) 2008;7(9):1178-83.
2008: Lin Z Ping; Zhu Yong-Lian; Johnson Dennis R; Rice Kevin P; Nottoli Timothy; Hains Bryan C; McGrath James; Waxman Stephen G; Sartorelli Alan C
Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response.
Molecular pharmacology 2008;73(1):243-51.
2008: Ishiguro Kimiko; Sartorelli Alan C
Relationship between the induction of leukemia cell differentiation and the enhancement of reporter gene expression in 3T3 Swiss cells.
Leukemia research 2008;32(1):89-96.
2008: Bordonaro Michael; Lazarova Darina L; Sartorelli Alan C
Hyperinduction of Wnt activity: a new paradigm for the treatment of colorectal cancer?
Oncology research 2008;17(1):1-9.
2007: Eaton Jana S; Lin Z Ping; Sartorelli Alan C; Bonawitz Nicholas D; Shadel Gerald S
Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis.
The Journal of clinical investigation 2007;117(9):2723-34.
2007: Bordonaro Michael; Lazarova Darina L; Sartorelli Alan C
The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors.
Experimental cell research 2007;313(8):1652-66.
2007: Lin Z Ping; Belcourt Michael F; Carbone Rocco; Eaton Jana S; Penketh Philip G; Shadel Gerald S; Cory Joseph G; Sartorelli Alan C
Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress.
Biochemical pharmacology 2007;73(6):760-72.
2007: Long Mary C; Allan Paula W; Luo Mei-Zhen; Liu Mao-Chin; Sartorelli Alan C; Parker William B
Evaluation of 3-deaza-adenosine analogues as ligands for adenosine kinase and inhibitors of Mycobacterium tuberculosis growth.
The Journal of antimicrobial chemotherapy 2007;59(1):118-21.
2006: Ishiguro Kimiko; Seow Helen A; Penketh Philip G; Shyam Krishnamurthy; Sartorelli Alan C
Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine.
Molecular cancer therapeutics 2006;5(4):969-76.
2006: Alvero Ayesha B; Chen Wei; Sartorelli Alan C; Schwartz Peter; Rutherford Thomas; Mor Gil
Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) induces apoptosis in ovarian cancer cells.
Journal of the Society for Gynecologic Investigation 2006;13(2):145-52.
2006: Cai Jiyang; Kirlin Ward G; Chen Yan; Yan Xuexian; Jones Dean P; Sartorelli Alan C
Overexpression of heat shock factor 1 inhibits butyrate-induced differentiation in colon cancer cells.
Cell stress & chaperones 2006;11(3):199-207.
2005: Ishiguro Kimiko; Shyam Krishnamurthy; Penketh Philip G; Sartorelli Alan C
Role of O6-alkylguanine-DNA alkyltransferase in the cytotoxic activity of cloretazine.
Molecular cancer therapeutics 2005;4(11):1755-63.
2005: Seow Helen A; Penketh Philip G; Shyam Krishnamurthy; Rockwell Sara; Sartorelli Alan C
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: an anticancer agent targeting hypoxic cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9282-7.
2005: Rice Kevin P; Penketh Philip G; Shyam Krishnamurthy; Sartorelli Alan C
Differential inhibition of cellular glutathione reductase activity by isocyanates generated from the antitumor prodrugs Cloretazine and BCNU.
Biochemical pharmacology 2005;69(10):1463-72.
2005: Seow Helen A; Belcourt Michael F; Penketh Philip G; Hodnick William F; Tomasz Maria; Rockwell Sara; Sartorelli Alan C
Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells.
Molecular pharmacology 2005;67(2):417-23.
2005: Haffty Bruce G; Wilson Lynn D; Son Yung H; Cho Edward I; Papac Rose J; Fischer Diana B; Rockwell Sara; Sartorelli Alan C; Ross Douglas A; Sasaki Clarence T; Fischer James J
Concurrent chemo-radiotherapy with mitomycin C compared with porfiromycin in squamous cell cancer of the head and neck: final results of a randomized clinical trial.
International journal of radiation oncology, biology, physics 2005;61(1):119-28.
2005: Baumann Raymond P; Seow Helen A; Shyam Krishnamurthy; Penketh Philip G; Sartorelli Alan C
The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activation.
Oncology research 2005;15(6):313-25.
2005: Liu Mao-Chin; Luo Mei-Zhen; Mozdziesz Diane E; Dutschman Ginger E; Gullen Elizabeth A; Cheng Yung-Chi; Sartorelli Alan C
Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.
Nucleosides, nucleotides & nucleic acids 2005;24(2):135-45.
2005: Liu Mao-Chin; Luo Mei-Zhen; Mozdziesz Diane E; Sartorelli Alan C
Synthesis and biological evaluation of 2- and 7-substituted 9-deazaadenosine analogues.
Nucleosides, nucleotides & nucleic acids 2005;24(1):45-62.
2004: Rice Anna M; Holtz Kathleen M; Karp Judith; Rollins Sandra; Sartorelli Alan C
Analysis of the relationship between Scl transcription factor complex protein expression patterns and the effects of LiCl on ATRA-induced differentiation in blast cells from patients with acute myeloid leukemia.
Leukemia research 2004;28(11):1227-37.
2004: Zeng Hao; Lin Z Ping; Sartorelli Alan C
Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06.
Biochemical pharmacology 2004;68(5):911-21.
2004: Seow Helen A; Penketh Philip G; Belcourt Michael F; Tomasz Maria; Rockwell Sara; Sartorelli Alan C
Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions.
The Journal of biological chemistry 2004;279(30):31606-12.
2004: Lazarova Darina L; Bordonaro Michael; Carbone Rocco; Sartorelli Alan C
Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate.
International journal of cancer. Journal international du cancer 2004;110(4):523-31.
2004: Ishiguro Kimiko; Sartorelli Alan C
Activation of transiently transfected reporter genes in 3T3 Swiss cells by the inducers of differentiation/apoptosis--dimethylsulfoxide, hexamethylene bisacetamide and trichostatin A.
European journal of biochemistry / FEBS 2004;271(12):2379-90.
2004: Lin Z Ping; Belcourt Michael F; Cory Joseph G; Sartorelli Alan C
Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors.
The Journal of biological chemistry 2004;279(26):27030-8.
2004: Rice Anna M; Li Jianming; Sartorelli Alan C
Combination of all-trans retinoic acid and lithium chloride surmounts a retinoid differentiation block induced by expression of Scl and Rbtn2 transcription factors in myeloid leukemia cells.
Leukemia research 2004;28(4):399-403.
2004: Penketh P G; Shyam K; Baumann R P; Remack J S; Brent T P; Sartorelli A C
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): I. Direct inhibition of O6-alkylguanine-DNA alkyltransferase (AGT) by electrophilic species generated by decomposition.
Cancer chemotherapy and pharmacology 2004;53(4):279-87.
2004: Baumann R P; Shyam K; Penketh P G; Remack J S; Brent T P; Sartorelli A C
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): II. Role of O6-alkylguanine-DNA alkyltransferase in cytotoxicity.
Cancer chemotherapy and pharmacology 2004;53(4):288-95.
2004: Bordonaro Michael; Lazarova Darina L; Carbone Rocco; Sartorelli Alan C
Modulation of Wnt-specific colon cancer cell kill by butyrate and lithium.
Oncology research 2004;14(9):427-38.
2004: Muramatsu Toshinari; Johnson Dennis R; Finch Rick A; Johnson Linda K; Leffert Janine J; Lin Z Ping; Pizzorno Giuseppe; Sartorelli Alan C
Age-related differences in vincristine toxicity and biodistribution in wild-type and transporter-deficient mice.
Oncology research 2004;14(7-8):331-43.
2004: Bordonaro Michael; Lazarova Darina L; Sartorelli Alan C
Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.
Nucleic acids research 2004;32(8):2660-74.
2004: Seow Helen A; Penketh Philip G; Baumann Raymond P; Sartorelli Alan C
Bioactivation and resistance to mitomycin C.
Methods in enzymology 2004;382():221-33.
2003: Holtz Kathleen M; Rice Anna M; Sartorelli Alan C
Lithium chloride inactivates the 20S proteasome from WEHI-3B D+ leukemia cells.
Biochemical and biophysical research communications 2003;303(4):1058-64.
2003: Holtz Kathleen M; Rockwell Sara; Tomasz Maria; Sartorelli Alan C
Nuclear overexpression of NADH:cytochrome b5 reductase activity increases the cytotoxicity of mitomycin C (MC) and the total number of MC-DNA adducts in Chinese hamster ovary cells.
The Journal of biological chemistry 2003;278(7):5029-34.
2002: Lin Z Ping; Johnson Dennis R; Finch Rick A; Belinsky Martin G; Kruh Gary D; Sartorelli Alan C
Comparative study of the importance of multidrug resistance-associated protein 1 and P-glycoprotein to drug sensitivity in immortalized mouse embryonic fibroblasts.
Molecular cancer therapeutics 2002;1(12):1105-14.
2002: Baumann Raymond P; Sherman David H; Sartorelli Alan C
Novel selection marker for mammalian cell transfection.
BioTechniques 2002;32(5):1030, 1032, 1034 passim.
2002: Murren John R; Pizzorno Giuseppe; DiStasio Susan A; McKeon Anne; Peccerillo Kathleen; Gollerkari Ashwin; McMurray Walter; Burtness Barbara A; Rutherford Thomas; Li Xin; Ho Peter T C; Sartorelli Alan
Phase I study of perillyl alcohol in patients with refractory malignancies.
Cancer biology & therapy 2002;1(2):130-5.
2002: Koay Debbie C; Nguyen Tr- Hung; Sartorelli Alan C
Distinct region of the granulocyte colony-stimulating factor receptor mediates proliferative signaling through activation of Janus kinase 2 and p44/42 mitogen-activated protein kinase.
Cellular signalling 2002;14(3):239-47.
2002: Bordonaro Michael; Lazarova Darina L; Augenlicht Leonard H; Sartorelli Alan C
Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate.
International journal of cancer. Journal international du cancer 2002;97(1):42-51.
2001: Liu M C; Luo M Z; Mozdziesz D E; Lin T S; Dutschman G E; Gullen E A; Cheng Y C; Sartorelli A C
Synthesis of halogen-substituted 3-deazaadenosine and 3-deazaguanosine analogues as potential antitumor/antiviral agents.
Nucleosides, nucleotides & nucleic acids 2001;20(12):1975-2000.
2001: Baumann R P; Hodnick W F; Seow H A; Belcourt M F; Rockwell S; Sherman D H; Sartorelli A C
Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
Cancer research 2001;61(21):7770-6.
2001: Rice A M; Sartorelli A C
Inhibition of 20 S and 26 S proteasome activity by lithium chloride: impact on the differentiation of leukemia cells by all-trans retinoic acid.
The Journal of biological chemistry 2001;276(46):42722-7.
2001: Liu M C; Luo M Z; Mozdziesz D E; Lin T S; Dutschman G E; Gullen E A; Cheng Y C; Sartorelli A C
Synthesis and biological evaluation of L- and D-configurations of 2',3'-dideoxy-4'-C-methyl-3'-oxacytidine analogues.
Bioorganic & medicinal chemistry letters 2001;11(17):2301-4.
2001: Penketh P G; Hodnick W F; Belcourt M F; Shyam K; Sherman D H; Sartorelli A C
Inhibition of DNA cross-linking by mitomycin C by peroxidase-mediated oxidation of mitomycin C hydroquinone.
The Journal of biological chemistry 2001;276(37):34445-52.
2001: Bishop B; Koay D C; Sartorelli A C; Regan L
Reengineering granulocyte colony-stimulating factor for enhanced stability.
The Journal of biological chemistry 2001;276(36):33465-70.
2001: Lazarova D L; Bordonaro M; Sartorelli A C
Transcriptional regulation of the vitamin D(3) receptor gene by ZEB.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(6):319-26.
2001: Sun H; Johnson D R; Finch R A; Sartorelli A C; Miller D W; Elmquist W F
Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice.
Biochemical and biophysical research communications 2001;284(4):863-9.
2001: Palom Y; Belcourt M F; Tang L Q; Mehta S S; Sartorelli A C; Pritsos C A; Pritsos K L; Rockwell S; Tomasz M
Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol.
Biochemical pharmacology 2001;61(12):1517-29.
2001: Finch R A; Shyam K; Penketh P G; Sartorelli A C
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino)carbonylhydrazine (101M): a novel sulfonylhydrazine prodrug with broad-spectrum antineoplastic activity.
Cancer research 2001;61(7):3033-8.
2001: Johnson D R; Finch R A; Lin Z P; Zeiss C J; Sartorelli A C
The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice.
Cancer research 2001;61(4):1469-76.
2001: Abraham E H; Sterling K M; Kim R J; Salikhova A Y; Huffman H B; Crockett M A; Johnston N; Parker H W; Boyle W E; Hartov A; Demidenko E; Efird J; Kahn J; Grubman S A; Jefferson D M; Robson S C; Thakar J H; Lorico A; Rappa G; Sartorelli A C; Okunieff P
Erythrocyte membrane ATP binding cassette (ABC) proteins: MRP1 and CFTR as well as CD39 (ecto-apyrase) involved in RBC ATP transport and elevated blood plasma ATP of cystic fibrosis.
Blood cells, molecules & diseases 2001;27(1):165-80.
2000: Robbiani D F; Finch R A; Jäger D; Muller W A; Sartorelli A C; Randolph G J
The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes.
Cell 2000;103(5):757-68.
2000: Luo M Z; Liu M C; Mozdziesz D E; Lin T S; Dutschman G E; Gullen E A; Cheng Y C; Sartorelli A C
Synthesis and biological evaluation of L- and D-configuration 1,3-dioxolane 5-azacytosine and 6-azathymine nucleosides.
Bioorganic & medicinal chemistry letters 2000;10(18):2145-8.
2000: Finch R A; Li J; Chou T C; Sartorelli A C
Maintenance of retinoic acid receptor alpha pools by granulocyte colony-stimulating factor and lithium chloride in all-trans retinoic acid-treated WEHI-3B leukemia cells: relevance to the synergistic induction of terminal differentiation.
Blood 2000;96(6):2262-8.
2000: Roberts K B; Urdaneta N; Vera R; Vera A; Gutierrez E; Aguilar Y; Ott S; Medina I; Sempere P; Rockwell S; Sartorelli A C; Fischer D B; Fischer J J
Interim results of a randomized trial of mitomycin C as an adjunct to radical radiotherapy in the treatment of locally advanced squamous-cell carcinoma of the cervix.
International journal of cancer. Journal international du cancer 2000;90(4):206-23.
2000: Murren J R; DiStasio S A; Lorico A; McKeon A; Zuhowski E G; Egorin M J; Sartorelli A C; Rappa G
Phase I and pharmacokinetic study of novobiocin in combination with VP-16 in patients with refractory malignancies.
Cancer journal (Sudbury, Mass.) 2000;6(4):256-65.
2000: Palom Y; Belcourt M F; Musser S M; Sartorelli A C; Rockwell S; Tomasz M
Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells.
Chemical research in toxicology 2000;13(6):479-88.
2000: Rappa G; Murren J R; Johnson L M; Lorico A; Sartorelli A C
Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells.
Anti-cancer drug design 2000;15(2):127-34.
2000: Finch R A; Liu M; Grill S P; Rose W C; Loomis R; Vasquez K M; Cheng Y; Sartorelli A C
Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.
Biochemical pharmacology 2000;59(8):983-91.
2000: Liu M C; Luo M Z; Mozdziesz D E; Lin T S; Dutschman G E; Gullen E A; Cheng Y C; Sartorelli A C
Synthesis and biological evaluation of 1,3-oxathiolane 5-azapyrimidine, 6-azapyrimidine, and fluorosubstituted 3-deazapyrimidine nucleosides.
Nucleosides, nucleotides & nucleic acids 2000;19(3):603-18.
2000: Penketh P G; Shyam K; Sartorelli A C
Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas.
Biochemical pharmacology 2000;59(3):283-91.
2000: Rappa G; Shyam K; Lorico A; Fodstad O; Sartorelli A C
Structure-activity studies of novobiocin analogs as modulators of the cytotoxicity of etoposide (VP-16).
Oncology research 2000;12(3):113-9.
1999: Belcourt M F; Penketh P G; Hodnick W F; Johnson D A; Sherman D H; Rockwell S; Sartorelli A C
Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10489-94.
1999: Rappa G; Finch R A; Sartorelli A C; Lorico A
New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models.
Biochemical pharmacology 1999;58(4):557-62.
1999: Li J; Finch R A; Sartorelli A C
Role of vitamin D3 receptor in the synergistic differentiation of WEHI-3B leukemia cells by vitamin D3 and retinoic acid.
Experimental cell research 1999;249(2):279-90.
1999: Koay D C; Sartorelli A C
Functional differentiation signals mediated by distinct regions of the cytoplasmic domain of the granulocyte colony-stimulating factor receptor.
Blood 1999;93(11):3774-84.
1999: Rao V V; Dahlheimer J L; Bardgett M E; Snyder A Z; Finch R A; Sartorelli A C; Piwnica-Worms D
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3900-5.
1999: Shyam K; Penketh P G; Shapiro M; Belcourt M F; Loomis R H; Rockwell S; Sartorelli A C
Hypoxia-selective nitrobenzyloxycarbonyl derivatives of 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazines.
Journal of medicinal chemistry 1999;42(5):941-6.
1999: Liu M C; Luo M Z; Mozdziesz D E; Lin T S; Dutschman G E; Cheng Y C; Sartorelli A C
Synthesis of 2'-methylene-substituted 5-azapyrimidine, 6-azapyrimidine, and 3-deazaguanine nucleoside analogues as potential antitumor/antiviral agents.
Nucleosides & nucleotides 1999;18(1):55-72.
1999: Xu J; Xiao H H; Sartorelli A C
Attenuation of the induced differentiation of HL-60 leukemia cells by mitochondrial chaperone HSP70.
Oncology research 1999;11(9):429-35.
1999: Finch R A; Liu M C; Cory A H; Cory J G; Sartorelli A C
Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity.
Advances in enzyme regulation 1999;39():3-12.
1998: Ishiguro K; Sartorelli A C
Coinduction of embryonic and adult-type globin mRNAs by sodium butyrate and trichostatin A in two murine interleukin-3-dependent bone marrow-derived cell lines.
Blood 1998;92(11):4383-93.
1998: Ishiguro K; Sartorelli A C
Characterization of the domains of the erythropoietin receptor necessary for induction of cell growth and differentiation.
Cytokine 1998;10(8):564-77.
1998: Chen Y; Sokoloski J A; Chu E; Sartorelli A C
Regulation of the expression of enzymes involved in the replication of DNA in chemically induced monocytic/macrophagic differentiation of HL-60 leukemia cells.
Leukemia research 1998;22(8):697-703.
1998: Chen Y; Sokoloski J A; Chu E; Sartorelli A C
Regulation of the expression of enzymes involved in the replication of DNA in chemically-induced granulocytic differentiation of HL-60 leukemia cells.
Leukemia research 1998;22(8):687-95.
1998: Li J; Finch R A; Xiao W; Sartorelli A C
Identification of a repressor of the differentiation of WEHI-3B D- leukemia cells.
Experimental cell research 1998;242(1):274-84.
1998: Belcourt M F; Hodnick W F; Rockwell S; Sartorelli A C
The intracellular location of NADH:cytochrome b5 reductase modulates the cytotoxicity of the mitomycins to Chinese hamster ovary cells.
The Journal of biological chemistry 1998;273(15):8875-81.
1998: Sokoloski J A; Narayanan R; Sartorelli A C
Enhancement by antisense oligonucleotides to NF-kappaB of the differentiation of HL-60 promyelocytic leukemia cells induced by vitamin D3.
Cancer letters 1998;125(1-2):157-64.
1998: Sokoloski J A; Sartorelli A C
Induction of the differentiation of HL-60 promyelocytic leukemia cells by nonsteroidal anti-inflammatory agents in combination with low levels of vitamin D3.
Leukemia research 1998;22(2):153-61.
1998: Palom Y; Belcourt M F; Kumar G S; Arai H; Kasai M; Sartorelli A C; Rockwell S; Tomasz M
Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
Oncology research 1998;10(10):509-21.
1998: Lin T S; Ishiguro K; Sartorelli A C
Role of gp55 in restoring the sensitivity of Friend murine erythroleukemia cells to erythropoietin by exposure to dimethyl sulfoxide.
Oncology research 1998;10(4):175-84.
1998: Belcourt M F; Hodnick W F; Rockwell S; Sartorelli A C
Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase.
Advances in enzyme regulation 1998;38():111-33.
1997: Lorico A; Rappa G; Finch R A; Yang D; Flavell R A; Sartorelli A C
Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione.
Cancer research 1997;57(23):5238-42.
1997: Rappa G; Lorico A; Flavell R A; Sartorelli A C
Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins.
Cancer research 1997;57(23):5232-7.
1997: Penketh P G; Shyam K; Sartorelli A C
Fluorometric assay for the determination of DNA-DNA cross-links utilizing Hoechst 33258 at neutral pH values.
Analytical biochemistry 1997;252(1):210-3.
1997: Hodnick W F; Sartorelli A C
Measurement of dicumarol-sensitive NADPH: (menadione-cytochrome c) oxidoreductase activity results in an artifactual assay of DT-diaphorase in cell sonicates.
Analytical biochemistry 1997;252(1):165-8.
1997: Cory J G; Cory A H; Lorico A; Rappa G; Sartorelli A C
Altered efflux properties of mouse leukemia L1210 cells resistant to 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone.
Anticancer research 1997;17(5A):3185-93.
1997: Ishiguro K; Sartorelli A C
Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin.
Blood 1997;90(6):2273-81.
1997: Rappa G; Lorico A; Liu M C; Kruh G D; Cory A H; Cory J G; Sartorelli A C
Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase.
Biochemical pharmacology 1997;54(6):649-55.
1997: Sokoloski J A; Hodnick W F; Mayne S T; Cinquina C; Kim C S; Sartorelli A C
Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3: possible relationship to NF-kappaB.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(9):1546-53.
1997: Haffty B G; Son Y H; Papac R; Sasaki C T; Weissberg J B; Fischer D; Rockwell S; Sartorelli A C; Fischer J J
Chemotherapy as an adjunct to radiation in the treatment of squamous cell carcinoma of the head and neck: results of the Yale Mitomycin Randomized Trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(1):268-76.
1997: Haffty B G; Son Y H; Wilson L D; Papac R; Fischer D; Rockwell S; Sartorelli A C; Ross D; Sasaki C T; Fischer J J
Bioreductive alkylating agent porfiromycin in combination with radiation therapy for the management of squamous cell carcinoma of the head and neck.
Radiation oncology investigations 1997;5(5):235-45.
1997: Sokoloski J A; Shyam K; Sartorelli A C
Induction of the differentiation of HL-60 promyelocytic leukemia cells by curcumin in combination with low levels of vitamin D3.
Oncology research 1997;9(1):31-9.
1996: Ishiguro K; Sartorelli A C
The response of IL-3 dependent B6SUtA bone marrow cells to both erythropoietin and chemical inducers of differentiation.
Cancer letters 1996;110(1-2):233-41.
1996: Lorico A; Rappa G; Flavell R A; Sartorelli A C
Double knockout of the MRP gene leads to increased drug sensitivity in vitro.
Cancer research 1996;56(23):5351-5.
1996: Liu M C; Lin T S; Cory J G; Cory A H; Sartorelli A C
Synthesis and biological activity of 3- and 5-amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone.
Journal of medicinal chemistry 1996;39(13):2586-93.
1996: Belcourt M F; Hodnick W F; Rockwell S; Sartorelli A C
Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase.
Biochemical pharmacology 1996;51(12):1669-78.
1996: Penketh P G; Shyam K; Patton C L; Sartorelli A C
Spectrophotometric assay for processes involving changes in hydrogen ion concentration in aqueous solution.
Analytical biochemistry 1996;238(1):46-9.
1996: Shyam K; Penketh P G; Loomis R H; Rose W C; Sartorelli A C
Antitumor 2-(aminocarbonyl)-1,2-bis(methylsulfonyl)-1-(2-chloroethyl)- hydrazines.
Journal of medicinal chemistry 1996;39(3):796-801.
1996: Belcourt M F; Hodnick W F; Rockwell S; Sartorelli A C
Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):456-60.
1996: Penketh P G; Shyam K; Sartorelli A C
Mechanisms of resistance to alkylating agents.
Cancer treatment and research 1996;87():65-81.
1995: Penketh P G; Shyam K; Sartorelli A C
Spectroscopic aqueous-phase assay for alkylating activity suitable for automation or multiwell plate application.
Analytical biochemistry 1995;231(2):452-5.
1995: Lorico A; Rappa G; Srimatkandada S; Catapano C V; Fernandes D J; Germino J F; Sartorelli A C
Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene.
Cancer research 1995;55(19):4352-60.
1995: Liu M C; Lin T S; Penketh P; Sartorelli A C
Synthesis and antitumor activity of 4- and 5-substituted derivatives of isoquinoline-1-carboxaldehyde thiosemicarbazone.
Journal of medicinal chemistry 1995;38(21):4234-43.
1995: Li J; Koay D C; Sartorelli A C
The role of DNA ploidy in the differentiation of WEHI-3B D- leukemia cells transfected with the granulocyte colony-stimulating factor receptor gene.
Experimental cell research 1995;219(2):579-88.
1995: Li J; Sartorelli A C
Granulocyte colony-stimulating factor receptor mediated cell growth and differentiation.
Oncology research 1995;7(12):591-601.
1995: Liu M C; Lin T S; Sartorelli A C
Chemical and biological properties of cytotoxic alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones.
Progress in medicinal chemistry 1995;32():1-35.
1995: Cory J G; Cory A H; Rappa G; Lorico A; Liu M C; Lin T S; Sartorelli A C
Structure-function relationships for a new series of pyridine-2-carboxaldehyde thiosemicarbazones on ribonucleotide reductase activity and tumor cell growth in culture and in vivo.
Advances in enzyme regulation 1995;35():55-68.
1995: Sartorelli A C; Belcourt M F; Hodnick W F; Keyes S R; Pritsos C A; Rockwell S
Preferential kill of hypoxic EMT6 mammary tumor cells by the bioreductive alkylating agent porfiromycin.
Advances in enzyme regulation 1995;35():117-30.
1994: Li J; Sartorelli A C
Evidence for the glycosylation of the granulocyte colony-stimulating factor receptor.
Biochemical and biophysical research communications 1994;205(1):238-44.
1994: Hodnick W F; Sartorelli A C
The pH-dependent reduction of Adriamycin catalysed by NADH:cytochrome b5 reductase.
Cancer letters 1994;84(2):149-54.
1994: Penketh P G; Shyam K; Sartorelli A C
Studies on the mechanism of decomposition and structural factors affecting the aqueous stability of 1,2-bis(sulfonyl)-1-alkylhydrazines.
Journal of medicinal chemistry 1994;37(18):2912-7.
1994: Cory J G; Cory A H; Rappa G; Lorico A; Liu M C; Lin T S; Sartorelli A C
Inhibitors of ribonucleotide reductase. Comparative effects of amino- and hydroxy-substituted pyridine-2-carboxaldehyde thiosemicarbazones.
Biochemical pharmacology 1994;48(2):335-44.
1994: Li J; King I; Sartorelli A C
Differentiation of WEHI-3B D+ myelomonocytic leukemia cells induced by ectopic expression of the protooncogene c-jun.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(7):743-51.
1994: Sartorelli A C; Hodnick W F; Belcourt M F; Tomasz M; Haffty B; Fischer J J; Rockwell S
Mitomycin C: a prototype bioreductive agent.
Oncology research 1994;6(10-11):501-8.
1993: Shyam K; Penketh P G; Divo A A; Loomis R H; Rose W C; Sartorelli A C
Synthesis and evaluation of 1-acyl-1,2-bis(methylsulfonyl)-2-(2- chloroethyl)hydrazines as antineoplastic agents.
Journal of medicinal chemistry 1993;36(23):3496-502.
1993: Rappa G; Lorico A; Sartorelli A C
Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin.
Cancer research 1993;53(22):5487-93.
1993: Bizanek R; Chowdary D; Arai H; Kasai M; Hughes C S; Sartorelli A C; Rockwell S; Tomasz M
Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
Cancer research 1993;53(21):5127-34.
1993: Hodnick W F; Sartorelli A C
Reductive activation of mitomycin C by NADH:cytochrome b5 reductase.
Cancer research 1993;53(20):4907-12.
1993: Haffty B G; Son Y H; Sasaki C T; Papac R; Fischer D; Rockwell S; Sartorelli A; Fischer J J
Mitomycin C as an adjunct to postoperative radiation therapy in squamous cell carcinoma of the head and neck: results from two randomized clinical trials.
International journal of radiation oncology, biology, physics 1993;27(2):241-50.
1993: Sokoloski J A; Sartorelli A C; Rosen C A; Narayanan R
Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes.
Blood 1993;82(2):625-32.
1993: Rockwell S; Sartorelli A C; Tomasz M; Kennedy K A
Cellular pharmacology of quinone bioreductive alkylating agents.
Cancer metastasis reviews 1993;12(2):165-76.
1993: Divo A A; Patton C L; Sartorelli A C
Evaluation of rhodamine 123 as a probe for monitoring mitochondrial function in Trypanosoma brucei spp.
The Journal of eukaryotic microbiology 1993;40(3):329-35.
1993: Sokoloski J A; Li J; Nigam A; Sartorelli A C
Induction of the differentiation of HL-60 and WEHI-3B D+ leukemia cells by lithium chloride.
Leukemia research 1993;17(5):403-10.
1993: Rockwell S; Hughes C S; Keyes S R; Sartorelli A C; Kennedy K A
Porfiromycin as an adjunct to radiotherapy in young and old mice.
Experimental gerontology 1993;28(3):281-93.
1993: Moore K G; Donadio A C; Sartorelli A C
Determination of type I transglutaminase in differentiating normal and neoplastic human keratinocytes by an in situ radioimmunoassay.
Biochemical and biophysical research communications 1993;192(2):381-5.
1993: Li J; Koay D C; Xiao H; Sartorelli A C
Regulation of the differentiation of WEHI-3B D+ leukemia cells by granulocyte colony-stimulating factor receptor.
The Journal of cell biology 1993;120(6):1481-9.
1993: Sartorelli A C; Tomasz M; Rockwell S
Studies on the mechanism of the cytotoxic action of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells.
Advances in enzyme regulation 1993;33():3-17.
1993: Yabushita H; Sartorelli A C
Effects of sodium butyrate, dimethylsulfoxide and dibutyryl cAMP on the poorly differentiated ovarian adenocarcinoma cell line AMOC-2.
Oncology research 1993;5(4-5):173-82.
1993: Sokoloski J A; Pizzorno G; Beardsley G P; Sartorelli A C
Evidence for a relationship between intracellular GTP levels and the induction of HL-60 leukemia cell differentiation by 5,10-dideazatetrahydrofolic acid (DDATHF).
Oncology research 1993;5(8):293-9.
1992: Lorico A; Rappa G; Sartorelli A C
Novobiocin-induced accumulation of etoposide (VP-16) in WEHI-3B D+ leukemia cells.
International journal of cancer. Journal international du cancer 1992;52(6):903-9.
1992: Goulet F; Moore K G; Sartorelli A C
Glycosylation of annexin I and annexin II.
Biochemical and biophysical research communications 1992;188(2):554-8.
1992: Liu M C; Lin T S; Sartorelli A C
Synthesis and antitumor activity of amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone.
Journal of medicinal chemistry 1992;35(20):3672-7.
1992: Wang Y; Liu M C; Lin T S; Sartorelli A C
Synthesis and antitumor activity of 3- and 5-hydroxy-4-methylpyridine-2-carboxaldehyde thiosemicarbazones.
Journal of medicinal chemistry 1992;35(20):3667-71.
1992: Leung M F; Sartorelli A C
The effects of microtubule disrupting drugs on the differentiation of HL-60 leukemia cells.
Leukemia research 1992;16(9):929-35.
1992: Rappa G; Lorico A; Sartorelli A C
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26).
International journal of cancer. Journal international du cancer 1992;51(5):780-7.
1992: Leung M F; Lin T S; Sartorelli A C
Changes in actin and actin-binding proteins during the differentiation of HL-60 leukemia cells.
Cancer research 1992;52(11):3063-6.
1992: Li J; Sartorelli A C
Synergistic induction of the differentiation of WEHI-3B D+ myelomonocytic leukemia cells by retinoic acid and granulocyte colony-stimulating factor.
Leukemia research 1992;16(6-7):571-6.
1992: Heimer R; Sartorelli A C
RNA-directed actions of 5-fluorouridine in hemin stimulated K-562 erythroleukemia cells.
Cancer biochemistry biophysics 1992;12(4):221-39.
1992: Moore K G; Sartorelli A C
Annexin I and involucrin are cross-linked by particulate transglutaminase into the cornified cell envelope of squamous cell carcinoma Y1.
Experimental cell research 1992;200(1):186-95.
1992: Rappa G; Lorico A; Sartorelli A C
Development and characterization of a WEHI-3B D+ monomyelocytic leukemia cell line resistant to novobiocin and cross-resistant to other topoisomerase II-targeted drugs.
Cancer research 1992;52(10):2782-90.
1992: DiGiovanna M P; Sartorelli A C
Differentiation stage specificity of tyrosine phosphorylation in response to granulocyte macrophage colony stimulating factor (GM-CSF).
Cancer letters 1992;63(1):15-22.
1992: Leung M F; Sokoloski J A; Sartorelli A C
Changes in microtubules, microtubule-associated proteins, and intermediate filaments during the differentiation of HL-60 leukemia cells.
Cancer research 1992;52(4):949-54.
1992: Moore K G; Goulet F; Sartorelli A C
Purification of annexin I and annexin II from human placental membranes by high-performance liquid chromatography.
Protein expression and purification 1992;3(1):1-7.
1992: Ishiguro K; Ho P T; Sartorelli A C
Characterization of the defect in a variant of HL-60 promyelocytic leukemia cells with reduced transferrin receptor expression.
Somatic cell and molecular genetics 1992;18(1):45-63.
1991: Sokoloski J A; Sartorelli A C; Handschumacher R E; Lee C W
Inhibition by pertussis toxin of the activation of Na(+)-dependent uridine transport in dimethyl-sulphoxide-induced HL-60 leukaemia cells.
The Biochemical journal 1991;280 ( Pt 2)():515-9.
1991: Giordano G; Peterson G; McMurray W J; Shyam K; Sartorelli A C
The electron impact, chemical ionization and fast atom bombardment positive ion mass spectra of 1,2-bis(sulfonyl)methylhydrazines.
Biological mass spectrometry 1991;20(11):693-8.
1991: DiGiovanna M P; Sartorelli A C
Myeloid differentiation associated tyrosine protein kinase activity in WEHI-3B murine monomyelocytic leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(10):869-78.
1991: Tomasz M; Hughes C S; Chowdary D; Keyes S R; Lipman R; Sartorelli A C; Rockwell S
Isolation, identification, and assay of [3H]-porfiromycin adducts of EMT6 mouse mammary tumor cell DNA: effects of hypoxia and dicumarol on adduct patterns.
Cancer communications 1991;3(7):213-23.
1991: Rockwell S; Keyes S R; Loomis R; Kelley M; Vyas D M; Wong H; Doyle T W; Sartorelli A C
Activity of C-7 substituted cyclic acetal derivatives of mitomycin C and porfiromycin against hypoxic and oxygenated EMT6 carcinoma cells in vitro and in vivo.
Cancer communications 1991;3(6):191-8.
1991: Lin T S; Zhu L Y; Xu S P; Divo A A; Sartorelli A C
Synthesis and antimalarial activity of 2-aziridinyl- and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivatives.
Journal of medicinal chemistry 1991;34(5):1634-9.
1991: Keyes S R; Rockwell S; Kennedy K A; Sartorelli A C
Distribution of porfiromycin in EMT6 solid tumors and normal tissues of BALB/c mice.
Journal of the National Cancer Institute 1991;83(9):632-7.
1991: Penketh P G; Divo A A; Shyam K; Patton C L; Sartorelli A C
The effects of the methylating agent 1,2-bis(methylsulfonyl)-1-methylhydrazine on morphology, DNA content and mitochondrial function of Trypanosoma brucei subspecies.
The Journal of protozoology 1991;38(3):172-7.
1991: Buddhu S; Penketh P G; Divo A A; Shyam K; Patton C L; Sartorelli A C
Enhancement of the trypanocidal activity of methyltriazenes in an animal model by the addition of an amidino group.
Acta tropica 1991;49(1):69-72.
1991: Lee C W; Sokoloski J A; Sartorelli A C; Handschumacher R E
Induction of the differentiation of HL-60 cells by phorbol 12-myristate 13-acetate activates a Na(+)-dependent uridine-transport system. Involvement of protein kinase C.
The Biochemical journal 1991;274 ( Pt 1)():85-90.
1991: Sokoloski J A; Sartorelli A C
Expression of memory to the terminal differentiation inducing activity of tiazofurin in HL-60 leukemia cells.
Leukemia research 1991;15(5):395-402.
1991: Sokoloski J A; Beardsley G P; Sartorelli A C
Induction of HL-60 leukemia cell differentiation by tetrahydrofolate inhibitors of de novo purine nucleotide biosynthesis.
Cancer chemotherapy and pharmacology 1991;28(1):39-44.
1991: Gamba-Vitalo C; DiGiovanna M P; Sartorelli A C
Effects of recombinant murine granulocyte-macrophage colony-stimulating factor in cyclophosphamide-treated mice.
Blood cells 1991;17(1):193-205; discussion 206-8.
1991: Sokoloski J A; Lee C W; Handschumacher R E; Nigam A; Sartorelli A C
Effects of uridine on the growth and differentiation of HL-60 leukemia cells.
Leukemia research 1991;15(11):1051-8.
1991: Ho P T; Ishiguro K; Wickstrom E; Sartorelli A C
Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides.
Antisense research and development 1991;1(4):329-42.
1991: Keyes S R; Loomis R; DiGiovanna M P; Pritsos C A; Rockwell S; Sartorelli A C
Cytotoxicity and DNA crosslinks produced by mitomycin analogs in aerobic and hypoxic EMT6 cells.
Cancer communications 1991;3(10-11):351-6.
1990: Rappa G; Lorico A; Sartorelli A C
Induction of the differentiation of WEHI-3B D+ monomyelocytic leukemia cells by inhibitors of topoisomerase II.
Cancer research 1990;50(20):6723-30.
1990: Shyam K; Penketh P G; Divo A A; Loomis R H; Patton C L; Sartorelli A C
Synthesis and evaluation of 1,2,2-tris(sulfonyl)hydrazines as antineoplastic and trypanocidal agents.
Journal of medicinal chemistry 1990;33(8):2259-64.
1990: Penketh P G; Shyam K; Divo A A; Patton C L; Sartorelli A C
Methylating agents as trypanocides.
Journal of medicinal chemistry 1990;33(2):730-2.
1990: Wiser M F; Sartorelli A C; Patton C L
Association of Plasmodium berghei proteins with the host erythrocyte membrane: binding to inside-out vesicles.
Molecular and biochemical parasitology 1990;38(1):121-34.
1990: Violette S M; King I; Browning J L; Pepinsky R B; Wallner B P; Sartorelli A C
Role of lipocortin I in the glucocorticoid induction of the terminal differentiation of a human squamous carcinoma.
Journal of cellular physiology 1990;142(1):70-7.
1990: Heimer R; Sartorelli A C
Reductions in gamma-globin mRNA levels restricted to the cytoplasm of 5-fluorouridine treated K-562 human erythroleukemia cells.
Cancer communications 1990;2(1):45-53.
1990: Niedbala M J; Bajetta S; Carbone R; Sartorelli A C
Regulation of human squamous cell carcinoma plasma membrane associated urokinase plasminogen activator by epidermal growth factor.
Cancer communications 1990;2(9):317-24.
1990: Niedbala M J; Sartorelli A C
Plasminogen activator mediated degradation of subendothelial extracellular matrix by human squamous carcinoma cell lines.
Cancer communications 1990;2(5):189-99.
1989: Violette S M; King I; Sartorelli A C
Induction of the terminal differentiation of a human squamous cell carcinoma by steroids with glucocorticoid activity.
Journal of steroid biochemistry 1989;33(5):1001-5.
1989: King I; Sartorelli A C
Epidermal growth factor receptor gene expression, protein kinase activity, and terminal differentiation of human malignant epidermal cells.
Cancer research 1989;49(20):5677-81.
1989: Pratviel G; Shyam K; Sartorelli A C
Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype.
Cancer biochemistry biophysics 1989;10(4):365-75.
1989: Constantinides P P; Ghosaini L; Inouchi N; Kitamura S; Seshadri R; Israel M; Sartorelli A C; Sturtevant J M
Interaction of N-alkylanthracyclines with lipid bilayers: correlations between partition coefficients, lipid phase distributions and thermotropic behavior.
Chemistry and physics of lipids 1989;51(2):105-18.
1989: Pritsos C A; Keyes S R; Sartorelli A C
Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
Cancer biochemistry biophysics 1989;10(4):289-98.
1989: Sokoloski J A; Beardsley G P; Sartorelli A C
Induction of HL-60 leukemia cell differentiation by the novel antifolate 5,10-dideazatetrahydrofolic acid.
Cancer research 1989;49(17):4824-8.
1989: Violette S M; King I; Sartorelli A C
Antagonistic effects of retinoic acid and hydrocortisone on terminal differentiation of human squamous carcinoma cells.
The Journal of investigative dermatology 1989;93(1):165-8.
1989: Lin T S; Xu S P; Zhu L Y; Cosby L A; Sartorelli A C
Synthesis of 2,3-diaziridinyl-1,4-naphthoquinone sulfonate derivatives as potential antineoplastic agents.
Journal of medicinal chemistry 1989;32(7):1467-71.
1989: Weissberg J B; Son Y H; Papac R J; Sasaki C; Fischer D B; Lawrence R; Rockwell S; Sartorelli A C; Fischer J J
Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer.
International journal of radiation oncology, biology, physics 1989;17(1):3-9.
1989: Rockwell S; Keyes S R; Sartorelli A C
Modulation of the cytotoxicity of porfiromycin by dicoumarol in vitro and in vivo.
Anticancer research 1989;9(4):817-20.
1989: Niedbala M J; Sartorelli A C
Regulation by epidermal growth factor of human squamous cell carcinoma plasminogen activator-mediated proteolysis of extracellular matrix.
Cancer research 1989;49(12):3302-9.
1989: Keyes S R; Rockwell S; Sartorelli A C
Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
Cancer research 1989;49(12):3310-3.
1989: Sokoloski J A; Blair O C; Carbone R; Sartorelli A C
Induction of the differentiation of synchronized HL-60 leukemia cells by tiazofurin.
Experimental cell research 1989;182(1):234-41.
1989: Ho P T; Ishiguro K; Sartorelli A C
Regulation of transferrin receptor in myeloid and monocytic differentiation of HL-60 leukemia cells.
Cancer research 1989;49(8):1989-95.
1989: Gamba-Vitalo C; Carman M D; Sartorelli A C
Development of neomycin-resistant WEHI-3B D+ murine cells as an in vivo model of acute nonlymphocytic leukemia.
Experimental hematology 1989;17(2):130-7.
1989: Xia X J; Gu X B; Sartorelli A C; Yu R K;
Effects of inducers of differentiation on protein kinase C and CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activities of HL-60 leukemia cells.
Journal of lipid research 1989;30(2):181-8.
1989: Heimer R; Sartorelli A C
RNA polymerase II transcripts as targets for 5-fluorouridine cytotoxicity: antagonism of 5-fluorouridine actions by alpha-amanitin.
Cancer chemotherapy and pharmacology 1989;24(2):80-6.
1989: Sokoloski J A; Beardsley G P; Sartorelli A C
Mechanism of the induction of the differentiation of HL-60 leukemia cells by antifolates.
Cancer communications 1989;1(3):199-207.
1989: Gamba-Vitalo C; Carman M D; Sartorelli A C
WEHI-3B D+ Y1 leukemia cells as a model system to assess the induction of differentiation in vivo.
Cancer communications 1989;1(3):157-65.
1989: Rockwell S; Keyes S R; Sartorelli A C
Modulation of the antineoplastic efficacy of mitomycin C by dicoumarol in vivo.
Cancer chemotherapy and pharmacology 1989;24(6):349-53.
1988: Dreyer R; Hawrot E; Sartorelli A C; Constantinides P P
Sedimentation field flow fractionation of fused unilamellar vesicles: comparison with electron microscopy and gel filtration.
Analytical biochemistry 1988;175(2):433-41.
1988: Rockwell S; Keyes S R; Sartorelli A C
Preclinical studies of porfiromycin as an adjunct to radiotherapy.
Radiation research 1988;116(1):100-13.
1988: Rockwell S; Keyes S R; Sartorelli A C
Modulation of the cytotoxicity of mitomycin C to EMT6 mouse mammary tumor cells by dicoumarol in vitro.
Cancer research 1988;48(19):5471-4.
1988: Divo A A; Sartorelli A C; Patton C L; Bia F J
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.
Antimicrobial agents and chemotherapy 1988;32(8):1182-6.
1988: Frank D A; Sartorelli A C
Biochemical characterization of tyrosine kinase and phosphotyrosine phosphatase activities of HL-60 leukemia cells.
Cancer research 1988;48(15):4299-306.
1988: Burres N S; Myers M T; Sartorelli A C
Evidence of multifactorial mechanisms in an adriamycin-resistant HL-60 promyelocytic leukemia cell line.
Cancer biochemistry biophysics 1988;10(1):47-57.
1988: Tatsumura T; Ariga T; Yu R K; Sartorelli A C
Changes in glycosphingolipids accompanying the differentiation of human squamous SQCC/Y1 cells.
Cancer research 1988;48(8):2121-4.
1988: Heimbrook D C; Shyam K; Sartorelli A C
Novel 1-haloalkyl-2-nitroimidazole bioreductive alkylating agents.
Anti-cancer drug design 1988;2(4):339-50.
1988: Sartorelli A C
Therapeutic attack of hypoxic cells of solid tumors: presidential address.
Cancer research 1988;48(4):775-8.
1988: Frank D A; Sartorelli A C
Alterations in tyrosine phosphorylation during the granulocytic maturation of HL-60 leukemia cells.
Cancer research 1988;48(1):52-8.
1988: Burke T G; Sartorelli A C; Tritton T R
Selectivity of the anthracyclines for negatively charged model membranes: role of the amino group.
Cancer chemotherapy and pharmacology 1988;21(4):274-80.
1987: Sokoloski J A; Sartorelli A C
Inhibition of the synthesis of glycoproteins and induction of the differentiation of HL-60 promyelocytic leukemia cells by 6-methylmercaptopurine ribonucleoside.
Cancer research 1987;47(23):6283-7.
1987: Penketh P G; Kennedy W P; Patton C L; Sartorelli A C
Competent metabolic utilization of hydrogen peroxide by trypanosomes.
Acta tropica 1987;44(4):461-2.
1987: Reiss M; Sartorelli A C
Regulation of growth and differentiation of human keratinocytes by type beta transforming growth factor and epidermal growth factor.
Cancer research 1987;47(24 Pt 1):6705-9.
1987: Shyam K; Hrubiec R T; Furubayashi R; Cosby L A; Sartorelli A C
1,2-Bis(sulfonyl)hydrazines. 3. Effects of structural modification on antineoplastic activity.
Journal of medicinal chemistry 1987;30(11):2157-61.
1987: Keyes S R; Rockwell S; Sartorelli A C
Correlation between drug uptake and selective toxicity of porfiromycin to hypoxic EMT6 cells.
Cancer research 1987;47(21):5654-7.
1987: Burke T G; Pritsos C A; Sartorelli A C; Tritton T R
The structural basis for anthracycline antibiotic stimulation of oxygen consumption by HL-60 cells and mitochondria.
Cancer biochemistry biophysics 1987;9(3):245-55.
1987: Lin J; Sartorelli A C
Stimulation by interferon of the differentiation of human promyelocytic leukemia (HL-60) cells produced by retinoic acid and actinomycin D.
Journal of interferon research 1987;7(4):379-87.
1987: Burke T G; Morin M J; Sartorelli A C; Lane P E; Tritton T R
Function of the anthracycline amino group in cellular transport and cytotoxicity.
Molecular pharmacology 1987;31(5):552-6.
1987: Gamba-Vitalo C; Blair O C; Tritton T R; Lane P A; Carbone R; Sartorelli A C
Cytotoxicity and differentiating actions of adriamycin in WEHI-3B D+ leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(3):188-97.
1986: Hrubiec R T; Shyam K; Cosby L A; Sartorelli A C
Synthesis and evaluation of 1-(arylsulfonyl)-2-[(methoxycarbonyl)sulfenyl]-1-methylhydrazines++ + as antineoplastic agents.
Journal of medicinal chemistry 1986;29(9):1777-9.
1986: Constantinides P P; Inouchi N; Tritton T R; Sartorelli A C; Sturtevant J M
A scanning calorimetric study of the interaction of anthracyclines with neutral and acidic phospholipids alone and in binary mixtures.
The Journal of biological chemistry 1986;261(22):10196-203.
1986: Shyam K; Furubayashi R; Hrubiec R T; Cosby L A; Sartorelli A C
1,2-bis(arylsulfonyl)hydrazines. 2. The influence of arylsulfonyl and aralkylsulfonyl substituents on antitumor and alkylating activity.
Journal of medicinal chemistry 1986;29(7):1323-5.
1986: Hrubiec R T; Shyam K; Cosby L A; Furubayashi R; Sartorelli A C
Synthesis and evaluation of 2-substituted 1-methyl-1-(4-tolylsulfonyl)hydrazines as antineoplastic agents.
Journal of medicinal chemistry 1986;29(7):1299-301.
1986: Sokoloski J A; Blair O C; Sartorelli A C
Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase.
Cancer research 1986;46(5):2314-9.
1986: Blair O C; Carbone R; Sartorelli A C
Differentiation of HL-60 promyelocytic leukemia cells: simultaneous determination of phagocytic activity and cell cycle distribution by flow cytometry.
Cytometry 1986;7(2):171-7.
1986: Gamba-Vitalo C; Blair O C; Keyes S R; Sartorelli A C
Differentiation of WEHI-3B D+ monomyelocytic leukemia cells by retinoic acid and aclacinomycin A.
Cancer research 1986;46(3):1189-94.
1985: Pritsos C A; Constantinides P P; Tritton T R; Heimbrook D C; Sartorelli A C
Use of high-performance liquid chromatography to detect hydroxyl and superoxide radicals generated from mitomycin C.
Analytical biochemistry 1985;150(2):294-9.
1985: Shyam K; Cosby L A; Sartorelli A C
Synthesis and evaluation of N,N'-bis(arylsulfonyl)hydrazines as antineoplastic agents.
Journal of medicinal chemistry 1985;28(4):525-7.
1985: Shyam K; Cosby L A; Sartorelli A C
Relationship between structure and antineoplastic activity of (arylsulfonyl)hydrazones of 4-pyridinecarboxaldehyde.
Journal of medicinal chemistry 1985;28(1):149-52.
1985: Blair O C; Carbone R; Sartorelli A C
Differentiation of HL-60 promyelocytic leukemia cells monitored by flow cytometric measurement of nitro blue tetrazolium (NBT) reduction.
Cytometry 1985;6(1):54-61.

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