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Takao Saruta

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Disorders

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Anatomy

Kidneys

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Japan

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Renal Circulation

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Nlandu Roger Ngatu; Maiko K Okajima; Asif Bhati Sabah; Shigetoshi Sano; Takao Saruta; Masamitsu Eitoku; Ryoji Hirota; Tatsuo Kaneko; Mitsuhiko Miyamura; Basilua Andre Muzembo; Mikiro Takaishi; Maki Yokogawa; Narufumi Suganuma
Anti-allergic effects of Vernonia amygdalina leaf extracts in hapten-induced atopic dermatitis-like disease in mice.
Naoki Oshima; Takao Saruta; Kamon Iigaya; Akira Kawai; Hiroo Kumagai; Yasuhiro Nishida; Hiroshi Onimaru; Hiroshi Itoh
Baro-excited neurons in the caudal ventrolateral medulla (CVLM) recorded using the whole-cell patch-clamp technique.
Toshio Ogihara; Yasuo Ohashi; Hiromi Rakugi; Takao Saruta; Kazuyuki Shimada; Kazuaki Shimamoto; Hiromichi Suzuki; Seiji Umemoto; Jitsuo Higaki; Sadayoshi Ito; Akira Kamiya; Hiroaki Matsuoka; Masunori Matsuzaki
Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial.

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2012: Nlandu Roger Ngatu; Maiko K Okajima; Asif Bhati Sabah; Shigetoshi Sano; Takao Saruta; Masamitsu Eitoku; Ryoji Hirota; Tatsuo Kaneko; Mitsuhiko Miyamura; Basilua Andre Muzembo; Mikiro Takaishi; Maki Yokogawa; Narufumi Suganuma
Anti-allergic effects of Vernonia amygdalina leaf extracts in hapten-induced atopic dermatitis-like disease in mice.
Allergology international : official journal of the Japanese Society of Allergology 2012;61(4):597-607.
2012: Naoki Oshima; Takao Saruta; Kamon Iigaya; Akira Kawai; Hiroo Kumagai; Yasuhiro Nishida; Hiroshi Onimaru; Hiroshi Itoh
Baro-excited neurons in the caudal ventrolateral medulla (CVLM) recorded using the whole-cell patch-clamp technique.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(5):500-6.
2012: Toshio Ogihara; Yasuo Ohashi; Hiromi Rakugi; Takao Saruta; Kazuyuki Shimada; Kazuaki Shimamoto; Hiromichi Suzuki; Seiji Umemoto; Jitsuo Higaki; Sadayoshi Ito; Akira Kamiya; Hiroaki Matsuoka; Masunori Matsuzaki
Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(4):441-8.
2012: Hiroo Kumagai; Tomokazu Matsuura; Toshiko Onami; Hiroshi Onimaru; Motohisa Osaka; Naoki Oshima; Katsufumi Sakata; Kamon Iigaya; Masaki Imai; Hiroshi Itoh; Tadashi Kamayachi; Chie Takimoto; Takao Saruta
Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(2):132-41.
2012: Shigeru Kageyama; Masaaki Miyakawa; Kouichi Mochizuki; Michio Nakayama; Yasuo Ohashi; Ikuo Saito; Takao Saruta; Masahiro Sugawara; Shinichiro Ueda
Optimal Combination of Effective ANtihypertensives (OCEAN) study: a prospective, randomized, open-label, blinded endpoint trial--rationale, design and results of a pilot study in Japan.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(2):221-7.
2012: Nlandu R Ngatu; Takao Saruta; Masamitsu Eitoku; Ryoji Hirota; Nangana Severin Luzitu; Tomomi Matsui; Basilua Andre Muzembo; Narufumi Suganuma
Brazilian green propolis extracts improve Tinea pedis interdigitalis and Tinea corporis.
Journal of alternative and complementary medicine (New York, N.Y.) 2012;18(1):8-9.
2011: Toshio Ogihara; Takao Saruta; Tosiya Sato; Kenji Ueshima; Shinji Yasuno; Akira Fujimoto; Kohshiro Fukiyama; Hiroaki Matsuoka; Kazuwa Nakao; Koji Oba
Long-term effects of candesartan and amlodipine on cardiovascular morbidity and mortality in Japanese high-risk hypertensive patients: the Candesartan Antihypertensive Survival Evaluation in Japan Extension Study (CASE-J Ex).
Hypertension research : official journal of the Japanese Society of Hypertension 2011;34(12):1295-301.
2011: Yuhei Kawano; Toshio Ogihara; Takao Saruta; Yoshio Goto; Masao Ishii
Association of blood pressure control and metabolic syndrome with cardiovascular risk in elderly Japanese: JATOS study.
American journal of hypertension 2011;24(11):1250-6.
2011: Masunori Matsuzaki; Toshio Ogihara; Yasuo Ohashi; Hiromi Rakugi; Takao Saruta; Kazuyuki Shimada; Hiromichi Suzuki; Norihiro Suzuki; Chuwa Tei; Seiji Umemoto; Keishi Abe; Tanenao Eto; Jitsuo Higaki; Sadayoshi Ito; Akira Kamiya; Kenjiro Kikuchi; Hiroaki Matsuoka
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial.
Journal of hypertension 2011;29(8):1649-59.
2011: Koji Oba; Toshio Ogihara; Takao Saruta; Tosiya Sato; Kazuwa Nakao
How to use marginal structural models in randomized trials to estimate the natural direct and indirect effects of therapies mediated by causal intermediates.
Clinical trials (London, England) 2011;8(3):277-87.
2011: Noriko Suda; Hirotaka Shibata; Isao Kurihara; Yayoi Ikeda; Sakiko Kobayashi; Kenichi Yokota; Ayano Murai-Takeda; Ken Nakagawa; Mototsugu Oya; Masaru Murai; William E Rainey; Takao Saruta; Hiroshi Itoh
Coactivation of SF-1-mediated transcription of steroidogenic enzymes by Ubc9 and PIAS1.
Endocrinology 2011;152(6):2266-77.
2011: Masahiro Asaka; Takao Saruta; Hidehiko Saito; Shogo Kanou; Shoji Kudo; Tamio Kuramoto
[The process leading up to publication of the 100th volume of the Journal of the Japanese Society of Internal Medicine. Discussion].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(1):2-19.
2011: Ikuo Saito; Shigeru Kageyama; Hiromichi Suzuki; Takao Saruta
Treatment of hypertension in patients 85 years of age or older: a J-BRAVE substudy.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2011;33(5):275-80.
2011: Kenji Ueshima; Shinji Yasuno; Akira Fujimoto; Koji Oba; Toshio Ogihara; Takao Saruta; Shiro Tanaka; Kazuwa Nakao
Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients. - Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial-.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(10):2411-6.
2011: Ikuo Saito; Hiromichi Suzuki; Shigeru Kageyama; Takao Saruta
Effect of antihypertensive treatment on cardiovascular events in elderly hypertensive patients: Japan's Benidipine Research on Antihypertensive Effects in the Elderly (J-BRAVE).
Clinical and experimental hypertension (New York, N.Y. : 1993) 2011;33(2):133-40.
2011: Toshio Ogihara; Akira Fujimoto; Kenji Ueshima; Kazuwa Nakao; Takao Saruta
Age-related differences in the effects of antihypertensive therapy on left ventricular hypertrophy in high-risk patients with hypertension-candesartan antihypertensive survival evaluation in Japan subanalysis.
Journal of the American Geriatrics Society 2011;59(1):180-1.
2010: Koichi Hayashi; Takao Saruta; Yoshio Goto; Masao Ishii
Impact of renal function on cardiovascular events in elderly hypertensive patients treated with efonidipine.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(11):1211-20.
2010: Toshihide Kawai; Izumi Takei; Mikiya Tokui; Osamu Funae; Kazunori Miyamoto; Mitsuhisa Tabata; Takumi Hirata; Takao Saruta; Akira Shimada; Hiroshi Itoh
Effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy in patients with type 2 diabetes, in relation to suppression of N(ɛ)-carboxymethyl lysine.
Journal of diabetes and its complications 2010;24(6):424-32.
2010: Kenji Ueshima; Shinji Yasuno; Koji Oba; Akira Fujimoto; Masashi Mukoyama; Toshio Ogihara; Takao Saruta; Kazuwa Nakao
Impact of left ventricular hypertrophy on the time-course of renal function in hypertensive patients – a subanalysis of the CASE-J trial –.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(10):2132-8.
2010: Toshio Ogihara; Takao Saruta; Hiromi Rakugi; Hiroaki Matsuoka; Kazuaki Shimamoto; Kazuyuki Shimada; Yutaka Imai; Kenjiro Kikuchi; Sadayoshi Ito; Tanenao Eto; Genjiro Kimura; Tsutomu Imaizumi; Shuichi Takishita; Hirotsugu Ueshima
Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study.
Hypertension 2010;56(2):196-202.
2010: Takao Saruta
[Aldosterone].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 7():354-7.
2010: Kazuwa Nakao; Masakazu Hirata; Koji Oba; Shinji Yasuno; Kenji Ueshima; Akira Fujimoto; Toshio Ogihara; Takao Saruta
Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(6):600-6.
2010: Kazuyuki Shimada; Toshio Ogihara; Takao Saruta; Kizuku Kuramoto
Effects of combination olmesartan medoxomil plus azelnidipine versus monotherapy with either agent on 24-hour ambulatory blood pressure and pulse rate in Japanese patients with essential hypertension: additional results from the REZALT study.
Clinical therapeutics 2010;32(5):861-81.
2010: Shinji Yasuno; Kenji Ueshima; Koji Oba; Akira Fujimoto; Masakazu Hirata; Toshio Ogihara; Takao Saruta; Kazuwa Nakao
Is pulse pressure a predictor of new-onset diabetes in high-risk hypertensive patients?: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial.
Diabetes care 2010;33(5):1122-7.
2010: Ayano Murai-Takeda; Hirotaka Shibata; Isao Kurihara; Sakiko Kobayashi; Kenichi Yokota; Noriko Suda; Yuko Mitsuishi; Rie Jo; Hirochika Kitagawa; Shigeaki Kato; Takao Saruta; Hiroshi Itoh
NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor.
The Journal of biological chemistry 2010;285(11):8084-93.
2010: Toshio Ogihara; Akira Fujimoto; Kazuwa Nakao; Takao Saruta
Effects of antihypertensive drugs in the prevention of new-onset diabetes mellitus in patients with hypertension at high-risk of cardiovascular events in relation to aging.
Journal of the American Geriatrics Society 2010;58(2):395-6.
2010: Koichi Hayashi; Koichiro Homma; Shu Wakino; Hirobumi Tokuyama; Naoki Sugano; Takao Saruta; Hiroshi Itoh
T-type Ca channel blockade as a determinant of kidney protection.
The Keio journal of medicine 2010;59(3):84-95.
2010: Yusuke Sakamaki; Hiroyuki Sasamura; Kaori Hayashi; Kimiko Ishiguro; Hironari Takaishi; Yasunori Okada; Jeanine D'Armiento; Takao Saruta; Hiroshi Itoh
Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-induced albuminuria and glomerulosclerosis.
Nephron. Experimental nephrology 2010;115(2):e22-32.
2009: Toshio Ogihara; Takao Saruta; Kazuyuki Shimada; Kizuku Kuramoto
A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension: the REZALT study.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(12):1148-54.
2009: Takashi Eguchi; Tatsuya Maruyama; Yoichi Ohno; Toshiyuki Morii; Keiichi Hirao; Hiroshi Hirose; Hiroshi Kawabe; Ikuo Saito; Matsuhiko Hayashi; Takao Saruta
Possible association of tumor necrosis factor receptor 2 gene polymorphism with severe hypertension using the extreme discordant phenotype design.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(9):775-9.
2009: Hiroyuki Sasamura; Kaori Hayashi; Kimiko Ishiguro; Hideaki Nakaya; Takao Saruta; Hiroshi Itoh
Prevention and regression of hypertension: role of renal microvascular protection.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(8):658-64.
2009: Shinji Yasuno; Kenji Ueshima; Koji Oba; Akira Fujimoto; Toshio Ogihara; Takao Saruta; Kazuwa Nakao
Clinical significance of left ventricular hypertrophy and changes in left ventricular mass in high-risk hypertensive patients: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan trial.
Journal of hypertension 2009;27(8):1705-12.
2009: Toshiyuki Morii; Yoichi Ohno; Norihiro Kato; Hiroshi Hirose; Hiroshi Kawabe; Keiichi Hirao; Takashi Eguchi; Tatsuya Maruyama; Matsuhiko Hayashi; Ikuo Saito; Yoshio Yazaki; Takao Saruta
CD36 single nucleotide polymorphism is associated with variation in low-density lipoprotein-cholesterol in young Japanese men.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2009;14(4):207-12.
2009: Takao Saruta; Koichi Hayashi; Toshio Ogihara; Kazuwa Nakao; Tsuguya Fukui; Kohshiro Fukiyama
Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease: subanalysis of the CASE-J Study.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(6):505-12.
2009: Kenji Ueshima; Shinji Yasuno; Koji Oba; Akira Fujimoto; Toshio Ogihara; Takao Saruta; Kazuwa Nakao
Effects of cardiac complications on cardiovascular events in Japanese high-risk hypertensive patients: subanalysis of the CASE-J trial.
Circulation journal : official journal of the Japanese Circulation Society 2009;73(6):1080-5.
2009: Takao Saruta
[The contribution of ARB to medical treatment].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(4):662-7.
2009: Toshio Ogihara; Takao Saruta; Hiromi Rakugi; Akira Fujimoto; Kenji Ueshima; Shinji Yasuno; Koji Oba; Kazuo Takeda; Jitsuo Higaki; Kazuwa Nakao
Relationship between the achieved blood pressure and the incidence of cardiovascular events in Japanese hypertensive patients with complications: a sub-analysis of the CASE-J trial.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(4):248-54.
2009: Toshio Ogihara; Takao Saruta; Hiromi Rakugi; Kazuaki Shimamoto; Sadayoshi Ito; Hiroaki Matsuoka; Masatsugu Horiuchi; Tsutomu Imaizumi; Shuichi Takishita; Jitsuo Higaki; Shigehiro Katayama; Ikuo Saito; Kazuyuki Shimada
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(2):163-7.
2009: Kenji Ueshima; Koji Oba; Shinji Yasuno; Akira Fujimoto; Tosiya Sato; Koshiro Fukiyama; Junichi Azuma; Toshio Ogihara; Takao Saruta; Kazuwa Nakao
Long-term effects of candesartan and amlodipine on cardiovascular mortality and morbidity in Japanese high-risk hypertensive patients: rationale, design, and characteristics of candesartan antihypertensive survival evaluation in Japan extension (CASE-J Ex).
Contemporary clinical trials 2009;30(1):97-101.
2008: Chie Takimoto; Hiroo Kumagai; Motohisa Osaka; Katsufumi Sakata; Toshiko Onami; Tadashi Kamayachi; Kamon Iigaya; Koichi Hayashi; Takao Saruta; Hiroshi Itoh
Candesartan and insulin reduce renal sympathetic nerve activity in hypertensive type 1 diabetic rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(10):1941-51.
2008: Toshio Ogihara; Akira Fujimoto; Kazuwa Nakao; Takao Saruta
ARB candesartan and CCB amlodipine in hypertensive patients: the CASE-J trial.
Expert review of cardiovascular therapy 2008;6(9):1195-201.
2008: Takao Saruta
[Definition and clinical characteristics of mild hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(8):1449-52.
2008: Naoki Oshima; Hiroo Kumagai; Hiroshi Onimaru; Akira Kawai; paul pilowsky; Kamon Iigaya; Chie Takimoto; Koichi Hayashi; Takao Saruta; Hiroshi Itoh
Monosynaptic excitatory connection from the rostral ventrolateral medulla to sympathetic preganglionic neurons revealed by simultaneous recordings.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(7):1445-54.
2008: Ikuo Saito; Keita Fujikawa; Takao Saruta
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(7):1399-405.
2008: Ikuo Saito; Makoto Kobayashi; Yasuyuki Matsushita; Asuka Mori; Kaname Kawasugi; Takao Saruta
Cost-utility analysis of antihypertensive combination therapy in Japan by a Monte Carlo simulation model.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(7):1373-83.
2008: Kyoko Yoshioka; Shu Wakino; Koichiro Homma; Takeshi Kanda; Satoru Tatematsu; Kazuhiro Hasegawa; Naoki Sugano; Osamu Ito; Ken Omata; Takao Saruta; Koichi Hayashi
Renal cytochrome P450 as a determinant of impaired natriuresis by PPAR-gamma ligands in ovariectomized obese rats.
Obesity (Silver Spring, Md.) 2008;16(5):965-71.
2008: Naoki Sugano; Shu Wakino; Takeshi Kanda; Satoru Tatematsu; Koichiro Homma; Kyoko Yoshioka; Kazuhiro Hasegawa; Y Hara; Y Suetsugu; T Yoshizawa; Y Hara; Y Utsunomiya; G Tokudome; T Hosoya; Takao Saruta; Koichi Hayashi
T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy.
Kidney international 2008;73(7):826-34.
2008: Norihiro Kato; Toshiyuki Miyata; Yasuharu Tabara; Tomohiro Katsuya; Kazuyuki Yanai; Hironori Hanada; Kei Kamide; Jun Nakura; Katsuhiko Kohara; Fumihiko Takeuchi; Hiroyuki Mano; Michio Yasunami; Akinori Kimura; Yoshikuni Kita; Hirotsugu Ueshima; Tomohiro Nakayama; Masayoshi Soma; Akira Hata; Akihiro Fujioka; Yuhei Kawano; Kazuwa Nakao; Akihiro Sekine; Teruhiko Yoshida; Yusuke Nakamura; Takao Saruta; Toshio Ogihara; Sumio Sugano; Tetsuro Miki; Hitonobu Tomoike
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
Human molecular genetics 2008;17(4):617-27.
2008: Toshio Ogihara; Takao Saruta; Kazuaki Shimamoto; Hiroaki Matsuoka; Hiromi Rakugi
Clinical efficacy of a new angiotensin II type 1 receptor blocker, pratosartan, in hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(2):281-7.
2008: Toshio Ogihara; Kazuwa Nakao; Tsuguya Fukui; Kohshiro Fukiyama; Kenji Ueshima; Koji Oba; Tosiya Sato; Takao Saruta
Effects of candesartan compared with amlodipine in hypertensive patients with high cardiovascular risks: candesartan antihypertensive survival evaluation in Japan trial.
Hypertension 2008;51(2):393-8.
2008: Kimiko Ishiguro; Hiroyuki Sasamura; Yusuke Sakamaki; Kaori Hayashi; Takao Saruta; Hiroshi Itoh
Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy.
Nephron. Experimental nephrology 2008;109(1):e20-8.
2007: Masaaki Matsumoto; Mayuko Ishiguro; Fuminori Ikeno; Mitsunori Ikeda; Reiko Kamijima; Yasuhiko Hirata; Takao Saruta; Hajime Kodama
Combined Bowen disease and extramammary Paget disease.
Journal of cutaneous pathology 2007;34 Suppl 1():47-51.
2007: Yoshifumi Saisho; Taro Maruyama; Hiroshi Hirose; Takao Saruta
Relationship between proinsulin-to-insulin ratio and advanced glycation endproducts in Japanese type 2 diabetic subjects.
Diabetes research and clinical practice 2007;78(2):182-8.
2007: Takao Saruta; Toshio Ogihara; Hiroaki Matsuoka; Hiromichi Suzuki; Megumi Toki; Yukio Hirayama; Kenji Nonaka; Kihito Takahashi
Antihypertensive efficacy and safety of fixed-dose combination therapy with losartan plus hydrochlorothiazide in Japanese patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(8):729-39.
2007: Satoru Tatematsu; Shu Wakino; Takeshi Kanda; Koichiro Homma; Kyoko Yoshioka; Kazuhiro Hasegawa; Naoki Sugano; Masumi Kimoto; Takao Saruta; Koichi Hayashi
Role of nitric oxide-producing and -degrading pathways in coronary endothelial dysfunction in chronic kidney disease.
Journal of the American Society of Nephrology : JASN 2007;18(3):741-9.
2007: Koichi Hayashi; Shu Wakino; Naoki Sugano; Yuri Ozawa; Koichiro Homma; Takao Saruta
Ca2+ channel subtypes and pharmacology in the kidney.
Circulation research 2007;100(3):342-53.
2007: Yoichi Ohno; Yosuke Ando; Tatsuya Maruyama; Toshiyuki Morii; Takashi Eguchi; Keiichi Hirao; Tsuneo Takenaka; Yoshihiko Kanno; Hiromichi Suzuki; Takao Saruta
Congenic substitution mapping for intracellular Ca2+ in spontaneously hypertensive rats.
American journal of hypertension 2007;20(2):172-6.
2007: Kamon Iigaya; Hiroo Kumagai; Hiroshi Onimaru; Akira Kawai; Naoki Oshima; Toshiko Onami; Chie Takimoto; Tadashi Kamayachi; Koichi Hayashi; Takao Saruta; Hiroshi Itoh
Novel axonal projection from the caudal end of the ventrolateral medulla to the intermediolateral cell column.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(2):R927-36.
2007: Kenichi Yokota; Hirotaka Shibata; Isao Kurihara; Sakiko Kobayashi; Noriko Suda; Ayano Murai-Takeda; Ikuo Saito; Hirochika Kitagawa; Shigeaki Kato; Takao Saruta; Hiroshi Itoh
Coactivation of the N-terminal transactivation of mineralocorticoid receptor by Ubc9.
The Journal of biological chemistry 2007;282(3):1998-2010.
2007: Kimiko Ishiguro; Hiroyuki Sasamura; Yusuke Sakamaki; Hiroshi Itoh; Takao Saruta
Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(1):63-75.
2007: Hiromichi Suzuki; Tsuneo Takenaka; Yoshihiko Kanno; Yoichi Ohno; Takao Saruta
Sodium and kidney disease.
Contributions to nephrology 2007;155():90-101.
2007: Hiroshi Kawabe; Ikuo Saito; Takao Saruta
Effects of nighttime alcohol intake on evening and next morning home blood pressure in Japanese normotensives.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2007;29(1):43-9.
2006: Hiroo Kumagai; Chie Takimoto; Kamon Iigaya; Tadashi Kamayachi; Takao Saruta; Hiroshi Itoh
[Effects of ARB in metabolic syndrome].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():599-606.
2006: Ikuo Saito; Takao Saruta
Controlled release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-combi) study.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(10):789-96.
2006: Takao Saruta
[Comparison of guidelines for hypertension therapy in each country].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 6():542-8.
2006: Takao Saruta
[Background for the revision of JSH2004].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 6():489-93.
2006: Takao Saruta
[Recent reports of the Framingham study].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 6():87-90.
2006: Koichiro Homma; Koichi Hayashi; Shu Wakino; Rie Irie; Makio Mukai; Hiroo Kumagai; Hirotaka Shibata; Takao Saruta
Primary malignant hepatic pheochromocytoma with negative adrenal scintigraphy.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(7):551-4.
2006: Hiroyuki Sasamura; Takao Saruta
[Extracellular matrix proteins and glycoproteins in the cardiovascular system].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():559-64.
2006: Hiroyuki Sasamura; Yudai Kitamura; Mari Nakamura; Munekazu Ryuzaki; Takao Saruta
Effects of the angiotensin receptor blocker candesartan on arterial stiffness and markers of extracellular matrix metabolism in patients with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2006;28(5):511-20.
2006: Kazuhiro Hasegawa; Shu Wakino; Toru Tanaka; Masumi Kimoto; Satoru Tatematsu; Takeshi Kanda; Kyoko Yoshioka; Koichiro Homma; Naoki Sugano; Masahiko Kurabayashi; Takao Saruta; Koichi Hayashi
Dimethylarginine dimethylaminohydrolase 2 increases vascular endothelial growth factor expression through Sp1 transcription factor in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(7):1488-94.
2006: Hiroto Matsuda; Koichi Hayashi; Mariko Meguro; Takao Saruta
A case report of progressive multifocal leukoencephalopathy in a human T-cell lymphotropic virus type 1-infected hemodialytic patient.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2006;10(3):291-5.
2006: Naohito Ishii; Hideki Ikenaga; Pamela K Carmines; Nobukazu Takada; Toshio Okazaki; Tatsuo Nagai; Tadakazu Maeda; Yoshikazu Aoki; Takao Saruta; Masato Katagiri
Impact of angiotensin-converting enzyme inhibition on renal cortical nitrotyrosine content during increased extracellular glucose concentration.
Clinical biochemistry 2006;39(6):633-9.
2006: Yusuke Sakamaki; Hiroyuki Sasamura; Shunya Ikeda; Naoki Ikegami; Takao Saruta
Comparison of health costs associated with treatment of hypertension with a calcium channel blocker and angiotensin-converting enzyme inhibitor in the United States and Japan.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(5):333-8.
2006: Takao Saruta
[Endocrine hypertension: progress in its diagnosis and treatment].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2006;95(4):613-5.
2006: Atsuhisa Sato; Takao Saruta; John W Funder
Combination therapy with aldosterone blockade and renin-angiotensin inhibitors confers organ protection.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(4):211-6.
2006: Mihoko Tsuji; Toshiaki Monkawa; Jun Yoshino; M Asai; S Fukuda; Hiroshi Kawachi; Fujio Shimizu; Matsuhiko Hayashi; Takao Saruta
Microarray analysis of a reversible model and an irreversible model of anti-Thy-1 nephritis.
Kidney international 2006;69(6):996-1004.
2006: Hiroo Kumagai; Toshiko Onami; Chie Takimoto; Kamon Iigaya; Takao Saruta
[Molecular mechanisms underlying proteinuria reduction and protection of nephrin and podocytes by ARB].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 2():639-46.
2006: Toshikatsu Shigihara; Yoichi Oikawa; Yasuhiko Kanazawa; Yoshiaki Okubo; Shosaku Narumi; Takao Saruta; Akira Shimada
Significance of serum CXCL10/IP-10 level in type 1 diabetes.
Journal of autoimmunity 2006;26(1):66-71.
2006: Takao Saruta
[Effect of calcium channel blocker in combination with an angiotensin II receptor blocker in Japanese patients with hypertension].
Drugs 2006;66 Spec No 1():19-21.
2006: Koichi Hayashi; Shu Wakino; Takeshi Kanda; Koichiro Homma; Naoki Sugano; Takao Saruta
Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury.
Journal of pharmacological sciences 2006;100(1):29-33.
2006: Takashi Araki; Matsuhiko Hayashi; Takao Saruta
Anion-exchange blocker enhances cytoplasmic vacuole formation and cell death in serum-deprived mouse kidney epithelial cells in mice.
Cell biology international 2006;30(1):93-100.
2006: Takeshi Kanda; Shu Wakino; Koichiro Homma; Kyoko Yoshioka; Satoru Tatematsu; Kazuhiro Hasegawa; Ichiro Takamatsu; Naoki Sugano; Koichi Hayashi; Takao Saruta
Rho-kinase as a molecular target for insulin resistance and hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):169-71.
2005: Toshikatsu Shigihara; Akira Shimada; Yoichi Oikawa; Hiroyuki Yoneyama; Yasuhiko Kanazawa; Yoshiaki Okubo; Kouji Matsushima; Eiji Yamato; Jun-Ichi Miyazaki; Akira Kasuga; Takao Saruta; Shosaku Narumi
CXCL10 DNA vaccination prevents spontaneous diabetes through enhanced beta cell proliferation in NOD mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):8401-8.
2005: Koichi Hayashi; Shu Wakino; Koichiro Homma; Naoki Sugano; Takao Saruta
Pathophysiological significance of T-type Ca2+ channels: role of T-type Ca2+ channels in renal microcirculation.
Journal of pharmacological sciences 2005;99(3):221-7.
2005: Shu Wakino; Shingo Hori; Takuya Mimura; Seitaroh Fujishima; Koichi Hayashi; Hajime Inamoto; Takao Saruta; Naoki Aikawa
Heat stroke with multiple organ failure treated with cold hemodialysis and cold continuous hemodiafiltration: a case report.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2005;9(5):423-8.
2005: Tomonori Yaguchi; Chie Takimoto; Hideki Uchimura; Kounosuke Konishi; Atsuhiro Ichihara; Kouichi Hayashi; Takao Saruta; Akinori Hashiguchi
[IgA nephropathy associated with polycythemia vera].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94(8):1612-4.
2005: Takao Saruta
[Aldosterone].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 8():328-31.
2005: Osamu Takase; Takeshi Marumo; Naohiko Imai; Junichi Hirahashi; Atsushi Takayanagi; Keiichi Hishikawa; Matsuhiko Hayashi; Nobuyoshi Shimizu; Toshiro Fujita; Takao Saruta
NF-kappaB-dependent increase in intrarenal angiotensin II induced by proteinuria.
Kidney international 2005;68(2):464-73.
2005: Tomokazu Matsuura; Hiroo Kumagai; Hiroshi Onimaru; Akira Kawai; Kamon Iigaya; Toshiko Onami; Katsufumi Sakata; Naoki Oshima; takeshi sugaya; Takao Saruta
Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice.
Hypertension 2005;46(2):349-54.
2005: Hiroshi Kawabe; Ikuo Saito; Takao Saruta
Status of home blood pressure measured in morning and evening: evaluation in normotensives and hypertensives in Japanese urban population.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(6):491-8.
2005: Koichi Hayashi; Shu Wakino; Yuri Ozawa; Koichiro Homma; Takeshi Kanda; Ken Okubo; Ichiro Takamatsu; Satoru Tatematsu; Hiroo Kumagai; Takao Saruta
Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney.
The Keio journal of medicine 2005;54(2):102-8.
2005: Takao Saruta
[The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2004)].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(6):952-8.
2005: Yoichi Ohno; Hiromichi Suzuki; Hisao Tanase; Keiichi Otsuka; Takayuki Sasaki; Taichi Suzawa; Toshiyuki Morii; Yosuke Ando; Tatsuya Maruyama; Takao Saruta
Quantitative trait loci mapping for intracellular calcium in spontaneously hypertensive rats.
American journal of hypertension 2005;18(5 Pt 1):666-71.
2005: Atsuhiro Ichihara; Matsuhiko Hayashi; Yuki Kaneshiro; Tomoko Takemitsu; Koichiro Homma; Yoshihiko Kanno; Mamoru Yoshizawa; Tomohiro Furukawa; Tsuneo Takenaka; Takao Saruta
Low doses of losartan and trandolapril improve arterial stiffness in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2005;45(5):866-74.
2005: Toshio Ogihara; Masunori Matsuzaki; Hiroaki Matsuoka; Kazuaki Shimamoto; Kazuyuki Shimada; Hiromi Rakugi; Seiji Umemoto; Akira Kamiya; Norihiro Suzuki; Hiroo Kumagai; Yasuo Ohashi; Shuichi Takishita; Keishi Abe; Takao Saruta
The combination therapy of hypertension to prevent cardiovascular events (COPE) trial: rationale and design.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(4):331-8.
2005: Hideki Uchimura; Takeshi Marumo; Osamu Takase; Hiroshi Kawachi; Fujio Shimizu; Matsuhiko Hayashi; Takao Saruta; Keiichi Hishikawa; Toshiro Fujita
Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2005;16(4):997-1004.
2005: Takeshi Kanda; Koichi Hayashi; Shu Wakino; Koichiro Homma; Kyoko Yoshioka; Kazuhiro Hasegawa; Naoki Sugano; Satoru Tatematsu; Ichiro Takamatsu; Takayuki Mitsuhashi; Takao Saruta
Role of Rho-kinase and p27 in angiotensin II-induced vascular injury.
Hypertension 2005;45(4):724-9.
2005: Shu Wakino; Koichi Hayashi; Satoru Tatematsu; Kazuhiro Hasegawa; Ichiro Takamatsu; Takeshi Kanda; Koichiro Homma; Kyoko Yoshioka; Naoki Sugano; Takao Saruta
Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylaminohydrolase in rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(3):255-62.
2005: Hiroo Kumagai; Toshiko Onami; Chie Takimoto; Kamon Iigaya; Takao Saruta
[Effects of central arginine vasopressin on the sympathetic nervous system].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():490-6.
2005: Takao Saruta
[Clinical entity of primary aldosteronism including idiopathic hyperaldosteronism and glucocorticoid remediable aldosteronism].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():277-82.
2005: Takao Saruta
[Discovery and significance of aldosterone].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():209-12.
2005: Toshiyuki Morii; Yoichi Ohno; Hiroshi Hirose; Hiroshi Kawabe; Tsutomu Ogata; Keiichi Hirao; Takashi Eguchi; Tatsuya Maruyama; Yoshihiko Kanno; Matsuhiko Hayashi; Ikuo Saito; Takao Saruta
Cellular insulin resistance in Epstein-Barr virus-transformed lymphoblasts from young insulin-resistant Japanese men.
Metabolism: clinical and experimental 2005;54(3):370-5.
2005: Takeo Ogawa; Hiroshi Hirose; Kiichi Miyashita; Ikuo Saito; Takao Saruta
GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men.
Metabolism: clinical and experimental 2005;54(3):296-9.
2005: Isao Kurihara; Hirotaka Shibata; Sakiko Kobayashi; Noriko Suda; Yayoi Ikeda; Kenichi Yokota; Ayano Murai; Ikuo Saito; William E Rainey; Takao Saruta
Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription.
The Journal of biological chemistry 2005;280(8):6721-30.
2005: Ken Okubo; Koichi Hayashi; Shu Wakino; Hiroto Matsuda; Eiji Kubota; Masanori Honda; Hirobumi Tokuyama; Tokunori Yamamoto; Fumihiko Kajiya; Takao Saruta
Role of asymmetrical dimethylarginine in renal microvascular endothelial dysfunction in chronic renal failure with hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(2):181-9.
2005: Hiroshi Kawabe; Ikuo Saito; Takao Saruta
Influence of repeated measurement on one occasion, on successive days, and on workdays on home blood pressure values.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2005;27(2-3):215-22.
2005: Atsuhiro Ichihara; Matsuhiko Hayashi; Yukako Koura; Yuko Tada; Yuki Kaneshiro; Takao Saruta
Long-term effects of statins on arterial pressure and stiffness of hypertensives.
Journal of human hypertension 2005;19(2):103-9.
2005: Yoshiyuki Kato; Yoichi Ohno; Matsuhiko Hayashi; Taichi Suzawa; Keigo Shibagaki; Takayuki Sasaki; Takao Saruta
Divergent effects of unilateral and subtotal nephrectomy on insulin sensitivity in rats.
Renal failure 2005;27(4):451-7.
2005: Atsuhisa Sato; Koichi Hayashi; Takao Saruta
Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease.
American journal of hypertension 2005;18(1):44-9.
2004: Masaki Asai; Toshiaki Monkawa; Takeshi Marumo; Seiichi Fukuda; Mihoko Tsuji; Jun Yoshino; Hiroshi Kawachi; Fujio Shimizu; Matsuhiko Hayashi; Takao Saruta
Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(12):971-8.
2004: Arata Itoh; Akira Shimada; Keiichi Kodama; Jiro Morimoto; Ryuji Suzuki; Yoichi Oikawa; Junichiro Irie; Yoshinori Nakagawa; Toshikatsu Shigihara; Yasuhiko Kanazawa; Yoshiaki Okubo; Yoshiko Motohashi; Taro Maruyama; Takao Saruta
GAD-reactive T cells were mainly detected in autoimmune-related type 1 diabetic patients with HLA DR9.
Annals of the New York Academy of Sciences 2004;1037():33-40.
2004: Jiro Morimoto; Hiroyuki Yoneyama; Akira Shimada; Toshikatsu Shigihara; Satoru Yamada; Yoichi Oikawa; Kouji Matsushima; Takao Saruta; Shosaku Narumi
CXC chemokine ligand 10 neutralization suppresses the occurrence of diabetes in nonobese diabetic mice through enhanced beta cell proliferation without affecting insulitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):7017-24.
2004: Koichiro Homma; Koichi Hayashi; Takeshi Kanda; Kyoko Yoshioka; Ichiro Takamatsu; Satoru Tatematsu; Hiroo Kumagai; Shu Wakino; Takao Saruta
Beneficial action of candesartan cilexetil plus amlodipine or ACE inhibitors in chronic nondiabetic renal disease.
Journal of human hypertension 2004;18(12):879-84.
2004: Hirotaka Shibata; Sakiko Kobayashi; Isao Kurihara; Noriko Suda; Kenichi Yokota; Ayano Murai; Yayoi Ikeda; Ikuo Saito; William E Rainey; Takao Saruta
COUP-TF and transcriptional co-regulators in adrenal steroidogenesis.
Endocrine research 2004;30(4):795-801.
2004: Sakiko Kobayashi; Hirotaka Shibata; Kenichi Yokota; Noriko Suda; Ayano Murai; Isao Kurihara; Ikuo Saito; Takao Saruta
FHL2, UBC9, and PIAS1 are novel estrogen receptor alpha-interacting proteins.
Endocrine research 2004;30(4):617-21.
2004: Kenichi Yokota; Hirotaka Shibata; Sakiko Kobayashi; Noriko Suda; Ayano Murai; Isao Kurihara; Ikuo Saito; Takao Saruta
Proteasome-mediated mineralocorticoid receptor degradation attenuates transcriptional response to aldosterone.
Endocrine research 2004;30(4):611-6.
2004: Yuko Tada; Atsuhiro Ichihara; Yukako Koura; Hirokazu Okada; Yuki Kaneshiro; Matsuhiko Hayashi; Takao Saruta
Ovariectomy enhances renal cortical expression and function of cyclooxygenase-2.
Kidney international 2004;66(5):1966-76.
2004: Hiroyuki Sasamura; Subaru Hashimoto; Sachio Kuribayashi; Koichi Ueno; Atsushi Takase; Matsuhiko Hayashi; Takao Saruta
Use of gadolinium contrast adrenal venography for the assessment of primary aldosteronism in a patient with iodine allergy.
Endocrine journal 2004;51(5):487-92.
2004: Yuri Ozawa; Koichi Hayashi; Takeshi Kanda; Koichiro Homma; Ichiro Takamatsu; Satoru Tatematsu; Kyoko Yoshioka; Hiroo Kumagai; Shu Wakino; Takao Saruta
Impaired nitric oxide- and endothelium-derived hyperpolarizing factor-dependent dilation of renal afferent arteriole in Dahl salt-sensitive rats.
Nephrology (Carlton, Vic.) 2004;9(5):272-7.
2004: Junichiro Irie; Akira Shimada; Yoichi Oikawa; Toshikatsu Shigihara; Takao Saruta
N-acetyl-cysteine accelerates transfer of diabetes into non-obese diabetic scid mice.
Diabetologia 2004;47(10):1803-9.
2004: Atsuhiro Ichihara; Matsuhiko Hayashi; Yuki Kaneshiro; Fumiaki Suzuki; Tsutomu Nakagawa; Yuko Tada; Yukako Koura; Akira Nishiyama; Hirokazu Okada; Mohammad Uddin; A H M Nurun Nabi; Yuichi Ishida; Tadashi Inagami; Takao Saruta
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.
The Journal of clinical investigation 2004;114(8):1128-35.
2004: Yasuyoshi Yamaji; Yuichi Nakazato; Naoki Oshima; Matsuhiko Hayashi; Takao Saruta
Oxidative stress induced by iron released from transferrin in low pH peritoneal dialysis solution.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(10):2592-7.
2004: Shu Wakino; Koichi Hayashi; Takeshi Kanda; Satoru Tatematsu; Koichiro Homma; Kyoko Yoshioka; Ichiro Takamatsu; Takao Saruta
Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2.
Circulation research 2004;95(5):e45-55.
2004: Toshio Ogihara; Takao Saruta; Hiroaki Matsuoka; Kazuaki Shimamoto; Toshiro Fujita; Kazuyuki Shimada; Yutaka Imai; Masaru Nishigaki
valsartan in elderly isolated systolic hypertension (VALISH) study: rationale and design.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(9):657-61.
2004: Keiichi Kodama; Akira Shimada; Osamu Funae; Jiro Morimoto; Junichiro Irie; Toshikatsu Shigihara; Yoichi Oikawa; Mikiya Tokui; Kenji Watanabe; Takao Saruta
Insulin-like growth factor-1 (IGF-1)-derived peptide protects against diabetes in NOD mice.
Autoimmunity 2004;37(6-7):481-7.
2004: Kazuo Kobayashi; Toshiaki Monkawa; Matsuhiko Hayashi; Takao Saruta
Expression of the Na+/H+ exchanger regulatory protein family in genetically hypertensive rats.
Journal of hypertension 2004;22(9):1723-30.
2004: Koichiro Azuma; Shuji Oguchi; Y Matsubara; T Mamizuka; Mitsuru Murata; H Kikuchi; Kiyoaki Watanabe; Fuminori Katsukawa; Hajime Yamazaki; Akira Shimada; Takao Saruta
Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(8):564-70.
2004: Yoshiki Yui; Tetsuya Sumiyoshi; Kazuhisa Kodama; Atsushi Hirayama; Hiroshi Nonogi; Katsuo Kanmatsuse; Hideki Origasa; Osamu Iimura; Masao Ishii; Takao Saruta; Kikuo Arakawa; Saichi Hosoda; Chuichi Kawai
Nifedipine retard was as effective as angiotensin converting enzyme inhibitors in preventing cardiac events in high-risk hypertensive patients with diabetes and coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) subgroup analysis.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(7):449-56.
2004: Takeo Ogawa; Hiroshi Hirose; Yukihiro Yamamoto; Kanako Nishikai; Kiichi Miyashita; Haruo Nakamura; Ikuo Saito; Takao Saruta
Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population.
Metabolism: clinical and experimental 2004;53(7):879-85.
2004: Naohito Ishii; Hideki Ikenaga; Pamela K Carmines; Yoshikazu Aoki; Zensuke Ogawa; Takao Saruta; Tetsuya Suga
High glucose augments arginase activity and nitric oxide production in the renal cortex.
Metabolism: clinical and experimental 2004;53(7):868-74.
2004: Toshikatsu Shigihara; Akira Shimada; Yoshihumi Saisho; Toshihide Kawai; Hiroshi Maruyama; Takao Saruta
Seroconversion of GAD antibody in unclassified diabetes with long duration of disease.
Diabetes care 2004;27(7):1836-7.
2004: Yukako Koura; Atsuhiro Ichihara; Yuko Tada; Yuki Kaneshiro; Hirokazu Okada; Constance J Temm; Matsuhiko Hayashi; Takao Saruta
Anandamide decreases glomerular filtration rate through predominant vasodilation of efferent arterioles in rat kidneys.
Journal of the American Society of Nephrology : JASN 2004;15(6):1488-94.
2004: Atsuhisa Sato; Takao Saruta
Aldosterone-induced organ damage: plasma aldosterone level and inappropriate salt status.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(5):303-10.
2004: Ryoko Shimizu-Hirota; Hiroyuki Sasamura; Mari Kuroda; Emi Kobayashi; Matsuhiko Hayashi; Takao Saruta
Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration.
Circulation research 2004;94(8):1067-74.
2004: Ryoko Shimizu-Hirota; Hiroyuki Sasamura; Mari Kuroda; Emi Kobayashi; Takao Saruta
Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family.
FEBS letters 2004;563(1-3):69-74.
2004: Yuri Ozawa; Koichi Hayashi; Shu Wakino; Takeshi Kanda; Koichiro Homma; Ichiro Takamatsu; Satoru Tatematsu; Kyoko Yoshioka; Takao Saruta
Free radical activity depends on underlying vasoconstrictors in renal microcirculation.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2004;26(3):219-29.
2004: Takao Saruta; Shigeru Kageyama; Toshio Ogihara; Kunio Hiwada; Masayo Ogawa; Kazuji Tawara; Marjorie Gatlin; Susan Garthwaite; Richard Bittman; Jeffrey Patrick
Efficacy and safety of the selective aldosterone blocker eplerenone in Japanese patients with hypertension: a randomized, double-blind, placebo-controlled, dose-ranging study.
Journal of clinical hypertension (Greenwich, Conn.) 2004;6(4):175-83; quiz 184-5.
2004: Takao Saruta
[Future aspects of the Japanese guidelines for the management of hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():639-43.
2004: Hiroo Kumagai; Toshiko Onami; Chie Takimoto; Kamon Iigaya; Takao Saruta
[Organ protection by angiotensin II receptor blockers].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():569-73.
2004: Hiroo Kumagai; Toshiko Onami; Kamon Iigaya; Koichi Hayashi; Takao Saruta
[Hypertension in acromegaly].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():508-11.
2004: Takao Saruta
[Cardiovascular events due to hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():327-32.
2004: Yoshiki Yui; Tetsuya Sumiyoshi; Kazuhisa Kodama; Atsushi Hirayama; Hiroshi Nonogi; Katsuo Kanmatsuse; Hideki Origasa; Osamu Iimura; Masao Ishii; Takao Saruta; Kikuo Arakawa; Saichi Hosoda; Chuichi Kawai
Comparison of nifedipine retard with angiotensin converting enzyme inhibitors in Japanese hypertensive patients with coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) randomized trial.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(3):181-91.
2004: Hiroto Matsuda; Koichi Hayashi; Shu Wakino; Eiji Kubota; Masanori Honda; Hirobumi Tokuyama; Ichiro Takamatsu; Satoru Tatematsu; Takao Saruta
Role of endothelium-derived hyperpolarizing factor in ACE inhibitor-induced renal vasodilation in vivo.
Hypertension 2004;43(3):603-9.
2004: Yoshiko Motohashi; Taro Maruyama; Mitsuru Murata; Satomi Nakano; Chizuko Maruyama; Shingo Kyotani; Motoo Tsushima; Takao Saruta
Role of genetic factors (CETP gene Taq I B polymorphism and Apo A-I gene Msp I polymorphism) in serum HDL-C levels in women.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2004;14(1):6-14.
2004: Sakiko Kobayashi; Hirotaka Shibata; Isao Kurihara; Kenichi Yokota; Noriko Suda; Ikuo Saito; Takao Saruta
Ubc9 interacts with chicken ovalbumin upstream promoter-transcription factor I and represses receptor-dependent transcription.
Journal of molecular endocrinology 2004;32(1):69-86.
2004: Seiko Matsunaga-Irie; Taro Maruyama; Yukihiro Yamamoto; Yoshiko Motohashi; Hiroshi Hirose; Akira Shimada; Mitsuru Murata; Takao Saruta
Relation between development of nephropathy and the p22phox C242T and receptor for advanced glycation end product G1704T gene polymorphisms in type 2 diabetic patients.
Diabetes care 2004;27(2):303-7.
2004: Ken Yajima; Akira Shimada; Hiroshi Hirose; Akira Kasuga; Takao Saruta
"Low dose" metformin improves hyperglycemia better than acarbose in type 2 diabetics.
The review of diabetic studies : RDS 2004;1(2):89-94.
2004: Hiroo Kumagai; Toshiko Onami; Kamon Iigaya; Chie Takimoto; Masaki Imai; Tomokazu Matsuura; Katsufumi Sakata; Naoki Oshima; Koichi Hayashi; Takao Saruta
Involvement of renal sympathetic nerve in pathogenesis of hypertension.
Contributions to nephrology 2004;143():32-45.
2004: Hiromichi Suzuki; Takao Saruta
An overview of blood pressure regulation associated with the kidney.
Contributions to nephrology 2004;143():1-15.
2004: Kanako Nishikai; Hiroshi Hirose; Tatsuya Ishii; Matsuhiko Hayashi; Ikuo Saito; Takao Saruta
Effects of leptin receptor gene 3'-untranslated region polymorphism on metabolic profiles in young Japanese men.
Journal of atherosclerosis and thrombosis 2004;11(2):73-8.
2004: Mari Kuroda; Hiroyuki Sasamura; Emi Kobayashi; Ryoko Shimizu-Hirota; Y Nakazato; Matsuhiko Hayashi; Takao Saruta
Glomerular expression of biglycan and decorin and urinary levels of decorin in primary glomerular disease.
Clinical nephrology 2004;61(1):7-16.
2004: Takao Saruta
[Treatment strategy on hypertensive cardiovascular damage observed in various guidelines].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(1):14-20.
2004: Yukihiro Yamamoto; Hiroshi Hirose; Ikuo Saito; Kanako Nishikai; Takao Saruta
Adiponectin, an adipocyte-derived protein, predicts future insulin resistance: two-year follow-up study in Japanese population.
The Journal of clinical endocrinology and metabolism 2004;89(1):87-90.
2003: Tsuguya Fukui; Mahbubur Rahman; Koichi Hayashi; Kazuo Takeda; Jitsuo Higaki; Tosiya Sato; Masanori Fukushima; Junichi Sakamoto; Satoshi Morita; Toshio Ogihara; Kohshiro Fukiyama; Masatoshi Fujishima; Takao Saruta
Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial of cardiovascular events in high-risk hypertensive patients: rationale, design, and methods.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(12):979-90.
2003: Koichi Hayashi; Yuri Ozawa; Shu Wakino; Takeshi Kanda; Koichiro Homma; Ichiro Takamatsu; Satoru Tatematsu; Takao Saruta
Cellular mechanism for mibefradil-induced vasodilation of renal microcirculation: studies in the isolated perfused hydronephrotic kidney.
Journal of cardiovascular pharmacology 2003;42(6):697-702.
2003: Jun Yoshino; Toshiaki Monkawa; Mihoko Tsuji; Matsuhiko Hayashi; Takao Saruta
Leukemia inhibitory factor is involved in tubular regeneration after experimental acute renal failure.
Journal of the American Society of Nephrology : JASN 2003;14(12):3090-101.
2003: Yoichi Oikawa; Akira Shimada; Akira Kasuga; Jiro Morimoto; Tadashi Osaki; Hideaki Tahara; Tatsushi Miyazaki; Fumi Tashiro; Eiji Yamato; Jun-Ichi Miyazaki; Takao Saruta
Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5865-75.
2003: Takeshi Kanda; Shu Wakino; Koichi Hayashi; Koichiro Homma; Yuri Ozawa; Takao Saruta
Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats.
Kidney international 2003;64(6):2009-19.
2003: Takashi Araki; Matsuhiko Hayashi; Takao Saruta
Cloning and characterization of a novel gene promoting ureteric bud branching in the metanephros.
Kidney international 2003;64(6):1968-77.
2003: Atsuhiro Ichihara; Matsuhiko Hayashi; Nobuhisa Hirota; Hirokazu Okada; Yukako Koura; Yuko Tada; Yuki Kaneshiro; Hirohiko Tsuganezawa; Takao Saruta
Angiotensin II type 2 receptor inhibits prorenin processing in juxtaglomerular cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(11):915-21.
2003: Hiroto Matsuda; Koichi Hayashi; Koichiro Homma; Kyoko Yoshioka; Takeshi Kanda; Ichiro Takamatsu; Satoru Tatematsu; Shu Wakino; Takao Saruta
Differing anti-proteinuric action of candesartan and losartan in chronic renal disease.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(11):875-80.
2003: Akira Shimada; Keiichi Kodama; Jiro Morimoto; Yoichi Oikawa; Junichiro Irie; Yoshinori Nakagawa; Koichi Matsubara; Taro Maruyama; Takao Saruta
Detection of GAD-reactive CD4+ cells in so-called "type 1B" diabetes.
Annals of the New York Academy of Sciences 2003;1005():378-86.
2003: Yoshinori Nakagawa; Akira Shimada; Yoichi Oikawa; Junichiro Irie; Toshikatsu Shigihara; Kazuhiro Tsumura; Shosaku Narumi; Takao Saruta
Two cases of "fulminant" type 1 diabetes suggesting involvement of autoimmunity.
Annals of the New York Academy of Sciences 2003;1005():359-61.
2003: Toshikatsu Shigihara; Akira Shimada; Satoru Yamada; Taro Maruyama; Hiroshi Hirose; Takao Saruta
Stromal cell-derived factor-1 chemokine gene polymorphism is not associated with onset age of Japanese type 1 diabetes.
Annals of the New York Academy of Sciences 2003;1005():328-31.
2003: Seiko Matsunaga; Taro Maruyama; Satoru Yamada; Yoshiko Motohashi; Toshikatsu Shigihara; Akira Shimada; Takao Saruta
Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) P22 Phox C242T gene polymorphism in type 1 diabetes.
Annals of the New York Academy of Sciences 2003;1005():324-7.
2003: Yoichi Oikawa; Akira Shimada; Satoru Yamada; Yoshiko Motohashi; Yoshinori Nakagawa; Junichiro Irie; Taro Maruyama; Takao Saruta
NKT cell frequency in Japanese type 1 diabetes.
Annals of the New York Academy of Sciences 2003;1005():230-2.
2003: Satoru Yamada; Akira Shimada; Keiichi Kodama; Jiro Morimoto; Ryuji Suzuki; Yoichi Oikawa; Junichiro Irie; Takao Saruta
Relationship between beta cell mass of NOD donors and diabetes development of NOD-scid recipients in adoptive transfer system.
Annals of the New York Academy of Sciences 2003;1005():211-4.
2003: Atsuhiro Ichihara; Matsuhiko Hayashi; Yukako Koura; Yuko Tada; Nobuhisa Hirota; Takao Saruta
Long-term effects of intensive blood-pressure lowering on arterial wall stiffness in hypertensive patients.
American journal of hypertension 2003;16(11 Pt 1):959-65.
2003: Yukako Kamiya; Atsuhiro Ichihara; Tomoko Yamashita; Osamu Takase; Matsuhiko Hayashi; Takao Saruta
[Left renal infarction due to dissecting aneurysm of the renal arterial branch].
Nihon Jinzo Gakkai shi 2003;45(7):695-700.
2003: Hiroshi Hirose; Ikuo Saito; Hiroshi Kawabe; Takao Saruta
Insulin resistance and hypertension: seven-year follow-up study in middle-aged Japanese men (the KEIO study).
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(10):795-800.
2003: Emi Kobayashi; Hiroyuki Sasamura; Mizuo Mifune; Ryoko Shimizu-Hirota; Mari Kuroda; Matsuhiko Hayashi; Takao Saruta
Hepatocyte growth factor regulates proteoglycan synthesis in interstitial fibroblasts.
Kidney international 2003;64(4):1179-88.
2003: Atsuhisa Sato; Mitsuhisa Tabata; Koichi Hayashi; Takao Saruta
Effects of the angiotensin II type 1 receptor antagonist candesartan, compared with angiotensin-converting enzyme inhibitors, on the urinary excretion of albumin and type IV collagen in patients with diabetic nephropathy.
Clinical and experimental nephrology 2003;7(3):215-20.
2003: Atsuhisa Sato; Takao Saruta
Aldosterone breakthrough during angiotensin-converting enzyme inhibitor therapy.
American journal of hypertension 2003;16(9 Pt 1):781-8.
2003: Koichiro Azuma; Fuminori Katsukawa; Shuji Oguchi; Mitsuru Murata; Hajime Yamazaki; Akira Shimada; Takao Saruta
Correlation between serum resistin level and adiposity in obese individuals.
Obesity research 2003;11(8):997-1001.
2003: Yoshiko Motohashi; Satoru Yamada; Tatsuo Yanagawa; Taro Maruyama; Ryuji Suzuki; Masaaki Niino; Toshiyuki Fukazawa; Akira Kasuga; Hiroshi Hirose; Koichi Matsubara; Akira Shimada; Takao Saruta
Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2003;88(7):3137-40.
2003: Koichi Hayashi; Yuri Ozawa; Keiji Fujiwara; Shu Wakino; Hiroo Kumagai; Takao Saruta
Role of actions of calcium antagonists on efferent arterioles--with special references to glomerular hypertension.
American journal of nephrology 2003;23(4):229-44.
2003: Tsuneo Takenaka; Yoichi Ohno; Koichi Hayashi; Takao Saruta; Hiromichi Suzuki
Governance of arteriolar oscillation by ryanodine receptors.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(1):R125-31.
2003: Hirotaka Shibata; Isao Kurihara; Sakiko Kobayashi; Kenichi Yokota; Noriko Suda; Ikuo Saito; Takao Saruta
Regulation of differential COUP-TF-coregulator interactions in adrenal cortical steroidogenesis.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):449-56.
2003: Nobuhisa Hirota; Atsuhiro Ichihara; Yukako Koura; Yuko Tada; Matsuhiko Hayashi; Takao Saruta
Transmural pressure control of prorenin processing and secretion in diabetic rat juxtaglomerular cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(6):493-501.
2003: Akira Nakamura; Koichi Hayashi; Yuri Ozawa; Keiji Fujiwara; Ken Okubo; Takeshi Kanda; Shu Wakino; Takao Saruta
Vessel- and vasoconstrictor-dependent role of rho/rho-kinase in renal microvascular tone.
Journal of vascular research 2003;40(3):244-51.
2003: Ken Yajima; Hiroshi Hirose; Haruhisa Fujita; Yoshiko Seto; Haruhisa Fujita; Kaname Ukeda; Kiichi Miyashita; Toshihide Kawai; Yukihiro Yamamoto; Takeo Ogawa; Taketo Yamada; Takao Saruta
Combination therapy with PPARgamma and PPARalpha agonists increases glucose-stimulated insulin secretion in db/db mice.
American journal of physiology. Endocrinology and metabolism 2003;284(5):E966-71.
2003: Hirobumi Tokuyama; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Masanori Honda; Ken Okubo; Ichiro Takamatsu; Yuri Ozawa; Takao Saruta
Role of nitric oxide and prostaglandin E2 in acute renal hypoperfusion.
Nephrology (Carlton, Vic.) 2003;8(2):65-71.
2003: Motohisa Osaka; Hiroo Kumagai; Katsufumi Sakata; Toshiko Onami; Ki H Chon; Mari A Watanabe; Takao Saruta
Low-order chaos in sympathetic nerve activity and scaling of heartbeat intervals.
Physical review. E, Statistical, nonlinear, and soft matter physics 2003;67(4 Pt 1):041915.
2003: Satoru Yamada; Junichiro Irie; Akira Shimada; Keiichi Kodama; Jiro Morimoto; Ryuji Suzuki; Yoichi Oikawa; Takao Saruta
Assessment of beta cell mass and oxidative peritoneal exudate cells in murine type 1 diabetes using adoptive transfer system.
Autoimmunity 2003;36(2):63-70.
2003: Osamu Takase; Junichi Hirahashi; Atsushi Takayanagi; Akihiro Chikaraishi; Takeshi Marumo; Yuri Ozawa; Matsuhiko Hayashi; Nobuyoshi Shimizu; Takao Saruta
Gene transfer of truncated IkappaBalpha prevents tubulointerstitial injury.
Kidney international 2003;63(2):501-13.
2003: Ikuo Saito; Takao Saruta
Effect of education through a periodic newsletter on persistence with antihypertensive therapy.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(2):159-62.
2003: Ryuji Suzuki; Akira Shimada; Taro Maruyama; Osamu Funae; Jiro Morimoto; Keiichi Kodama; Yoichi Oikawa; Akira Kasuga; Koichi Matsubara; Takao Saruta; Shosaku Narumi
T-cell function in anti-GAD65(+)diabetes with residual beta-cell function.
Journal of autoimmunity 2003;20(1):83-90.
2003: Koichi Hayashi; Hiroo Kumagai; Takao Saruta
Effect of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment.
American journal of hypertension 2003;16(2):116-22.
2003: Takashi Araki; Matsuhiko Hayashi; Keiko Nakanishi; Nobuhiro Morishima; Takao Saruta
Caspase-9 takes part in programmed cell death in developing mouse kidney.
Nephron. Experimental nephrology 2003;93(3):e117-24.
2003: Hirotaka Shibata; Sakiko Kobayashi; Isao Kurihara; Ikuo Saito; Takao Saruta
Nuclear receptors and co-regulators in adrenal tumors.
Hormone research 2003;59 Suppl 1():85-93.
2003: Atsuhisa Sato; Koichi Hayashi; Mitsuhide Naruse; Takao Saruta
Effectiveness of aldosterone blockade in patients with diabetic nephropathy.
Hypertension 2003;41(1):64-8.
2002: Koichi Hayashi; Takeshi Kanda; Koichiro Homma; Hirobumi Tokuyama; Ken Okubo; Ichiro Takamatsu; Satoru Tatematsu; Hiroo Kumagai; Takao Saruta
Altered renal microvascular response in Zucker obese rats.
Metabolism: clinical and experimental 2002;51(12):1553-61.
2002: Atsuhiro Ichihara; Matsuhiko Hayashi; Yukako Koura; Yuko Tada; takeshi sugaya; Nobuhisa Hirota; Takao Saruta
Blunted tubuloglomerular feedback by absence of angiotensin type 1A receptor involves neuronal NOS.
Hypertension 2002;40(6):934-9.
2002: Yuri Ozawa; Koichi Hayashi; Takahiko Nagahama; Keiji Fujiwara; Takeshi Kanda; Koichiro Homma; Takao Saruta
Distinct role of nitric oxide and endothelium-derived hyperpolarizing factor in renal microcirculation. Studies in the isolated perfused hydronephrotic kidney.
Nephron 2002;92(4):905-13.
2002: Isao Kurihara; Hirotaka Shibata; Sakiko Kobayashi; Ikuo Saito; Takao Saruta
A ring-finger protein CIP-2 is a novel regulator of COUP-TF action in the adrenal cortex.
Endocrine research 2002;28(4):581.
2002: Sakiko Kobayashi; Hirotaka Shibata; Isao Kurihara; Ikuo Saito; Takao Saruta
CIP-1 is a novel corepressor for nuclear receptor COUP-TF: a potential negative regulator in adrenal steroidogenesis.
Endocrine research 2002;28(4):579.
2002: Hiroto Matsuda; Koichi Hayashi; Koki Arakawa; Eiji Kubota; Masanori Honda; Hirobumi Tokuyama; Hiromichi Suzuki; Tokunori Yamamoto; Fumihiko Kajiya; Takao Saruta
Distinct modulation of superficial and juxtamedullary arterioles by prostaglandin in vivo.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(6):901-10.
2002: Atsuhisa Sato; Matsuhiko Hayashi; Takao Saruta
Relative long-term effects of spironolactone in conjunction with an angiotensin-converting enzyme inhibitor on left ventricular mass and diastolic function in patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(6):837-42.
2002: Yukihiro Yamamoto; Hiroshi Hirose; Kiichi Miyashita; Kanako Nishikai; Ikuo Saito; Matsuo Taniyama; Motowo Tomita; Takao Saruta
PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population.
Metabolism: clinical and experimental 2002;51(11):1407-9.
2002: Yusuke Jo; Atsuhiro Ichihara; Takashi Eguchi; Isao Kurihara; Akinori Hashiguchi; Konosuke Konishi; Matsuhiko Hayashi; Takao Saruta
[A case of diabetic glomerulosclerosis without concurrent diabetes mellitus].
Nihon Jinzo Gakkai shi 2002;44(7):552-7.
2002: Satoru Yamada; Akira Shimada; Takao Saruta
[Rhabdomyolysis in the diabetic state].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 10():443-8.
2002: Hiroo Kumagai; Katsufumi Sakata; Tomokazu Matsuura; Masaki Imai; Toshiko Onami; Kamon Iigaya; Takao Saruta
[Comparison of ARB and ACEI for renoprotection in chronic glomerulonephritis].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(10):2005-13.
2002: Tomokazu Matsuura; Hiroo Kumagai; Akira Kawai; Hiroshi Onimaru; Masaki Imai; Naoki Oshima; Katsufumi Sakata; Takao Saruta
Rostral ventrolateral medulla neurons of neonatal Wistar-Kyoto and spontaneously hypertensive rats.
Hypertension 2002;40(4):560-5.
2002: Yoichi Oikawa; Akira Shimada; Satoru Yamada; Yoshiko Motohashi; Yoshinori Nakagawa; Junichiro Irie; Taro Maruyama; Takao Saruta
High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes.
Diabetes care 2002;25(10):1818-23.
2002: Kiyoshi Kurokawa; Keishi Abe; Takao Saruta; Masaaki Arakawa; Ryuichi Kikkawa; Naohiko Ueda; Kaoru Onoyama; Kimio Tomita; Nobuya Ogawa
Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2002;3(3):167-75.
2002: Hirobumi Tokuyama; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Masanori Honda; Ken Okubo; Yuri Ozawa; Takao Saruta
Distinct role of intrarenal cyclooxygenase-1/2 in chronic unilateral renal ischemia.
Nephron 2002;92(1):183-91.
2002: Mari Kuroda; Hiroyuki Sasamura; Ryoko Shimizu-Hirota; Mizuo Mifune; Hideaki Nakaya; Emi Kobayashi; Matsuhiko Hayashi; Takao Saruta
Glucocorticoid regulation of proteoglycan synthesis in mesangial cells.
Kidney international 2002;62(3):780-9.
2002: Yukihiro Yamamoto; Hiroshi Hirose; Ikuo Saito; Motowo Tomita; Matsuo Taniyama; Koichi Matsubara; Yasunori Okazaki; Tatsuya Ishii; Kanako Nishikai; Takao Saruta
Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population.
Clinical science (London, England : 1979) 2002;103(2):137-42.
2002: Atsuhiro Ichihara; Matsuhiko Hayashi; Munekazu Ryuzaki; Michiko Handa; Tomohiro Furukawa; Takao Saruta
Fluvastatin prevents development of arterial stiffness in haemodialysis patients with type 2 diabetes mellitus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(8):1513-7.
2002: Hideaki Nakaya; Hiroyuki Sasamura; Mizuo Mifune; Ryoko Shimizu-Hirota; Mari Kuroda; Matsuhiko Hayashi; Takao Saruta
Prepubertal treatment with angiotensin receptor blocker causes partial attenuation of hypertension and renal damage in adult Dahl salt-sensitive rats.
Nephron 2002;91(4):710-8.
2002: Tsuneo Takenaka; Hiromichi Suzuki; Hirokazu Okada; Tsutomu Inoue; Yoshihiko Kanno; Yuri Ozawa; Koichi Hayashi; Takao Saruta
Transient receptor potential channels in rat renal microcirculation: actions of angiotensin II.
Kidney international 2002;62(2):558-65.
2002: Katsufumi Sakata; Hiroo Kumagai; Motohisa Osaka; Toshiko Onami; Tomokazu Matsuura; Masaki Imai; Takao Saruta
Potentiated sympathetic nervous and renin-angiotensin systems reduce nonlinear correlation between sympathetic activity and blood pressure in conscious spontaneously hypertensive rats.
Circulation 2002;106(5):620-5.
2002: Junichi Hirahashi; Shigeru Kuramochi; Konosuke Konishi; Akihiro Chikaraishi; Osamu Takase; Matsuhiko Hayashi; Takao Saruta
Glomerulonephritis with microtubular deposits associated with cryoglobulinemia and chronic active hepatitis.
Pathology international 2002;52(7):483-7.
2002: Yuichi Nakazato; Yasuyoshi Yamaji; Naoki Oshima; Matsuhiko Hayashi; Takao Saruta
Calcification and osteopontin localization in the peritoneum of patients on long-term continuous ambulatory peritoneal dialysis therapy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(7):1293-303.
2002: Hirobumi Tokuyama; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Masanori Honda; Ken Okubo; Ichiro Takamatsu; Satoru Tatematsu; Yuri Ozawa; Shu Wakino; Takao Saruta
Differential regulation of elevated renal angiotensin II in chronic renal ischemia.
Hypertension 2002;40(1):34-40.
2002: Tadashi Yoshida; Jun Yoshino; Matsuhiko Hayashi; Takao Saruta
Identification of a renal proximal tubular cell-specific enhancer in the mouse 25-hydroxyvitamin d 1alpha-hydroxylase gene.
Journal of the American Society of Nephrology : JASN 2002;13(6):1455-63.
2002: Hirobumi Tokuyama; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Masanori Honda; Ken Okubo; Yuri Ozawa; Takao Saruta
Stenosis-dependent role of nitric oxide and prostaglandins in chronic renal ischemia.
American journal of physiology. Renal physiology 2002;282(5):F859-65.
2002: Toshihide Kawai; Hiroshi Hirose; Yoshiko Seto; Haruhisa Fujita; Hiroshi Fujita; Kaname Ukeda; Takao Saruta
Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma.
Diabetes research and clinical practice 2002;56(2):83-92.
2002: Taro Maruyama; Hiroshi Murayama; Atsuo Nagata; Akira Shimada; Akira Kasuga; Takao Saruta
Anti-insulin-like growth factor-1 autoantibodies in type 1 diabetes.
Annals of the New York Academy of Sciences 2002;958():267-70.
2002: Isao Kurihara; Hirotaka Shibata; Toshihiko Suzuki; Takashi Ando; Sakiko Kobayashi; Matsuhiko Hayashi; Ikuo Saito; Takao Saruta
Expression and regulation of nuclear receptor coactivators in glucocorticoid action.
Molecular and cellular endocrinology 2002;189(1-2):181-9.
2002: Takao Saruta
[History of cardiology in the last 100 years: Hypertension].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2002;91(3):937-41.
2002: Koichi Hayashi; Hiroto Matsuda; Masanori Honda; Yuri Ozawa; Hirobumi Tokuyama; Ken Okubo; Ichiro Takamatsu; Takeshi Kanda; Satoru Tatematsu; Koichiro Homma; Takao Saruta
Impact of calcium antagonists on bleeding time in patients with chronic renal failure.
Journal of human hypertension 2002;16(3):199-203.
2002: Hiroshi Hirose; Toshihide Kawai; Yukihiro Yamamoto; Matsuo Taniyama; Motowo Tomita; Koichi Matsubara; Yasunori Okazaki; Tatsuya Ishii; Yuko Oguma; Izumi Takei; Takao Saruta
Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes.
Metabolism: clinical and experimental 2002;51(3):314-7.
2002: Akira Shimada; Jiro Morimoto; Keiichi Kodama; Yoichi Oikawa; Junichiro Irie; Yoshinori Nakagawa; Shosaku Narumi; Takao Saruta
T-cell-mediated autoimmunity may be involved in fulminant type 1 diabetes.
Diabetes care 2002;25(3):635-6.
2002: Nobuhisa Hirota; Atsuhiro Ichihara; Yukako Koura; Matsuhiko Hayashi; Takao Saruta
Phospholipase D contributes to transmural pressure control of prorenin processing in juxtaglomerular cell.
Hypertension 2002;39(2 Pt 2):363-7.
2002: Takashi Araki; Matsuhiko Hayashi; Naohide Watanabe; Hirotaka Kanuka; Jun Yoshino; Masayuki Miura; Takao Saruta
Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Biochemical and biophysical research communications 2002;290(4):1275-81.
2001: Ryoko Shimizu-Hirota; Hiroyuki Sasamura; Mizuo Mifune; Hideaki Nakaya; Mari Kuroda; Matsuhiko Hayashi; Takao Saruta
Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors.
Journal of the American Society of Nephrology : JASN 2001;12(12):2609-15.
2001: Tatsuya Ishii; Hiroshi Hirose; Toshihide Kawai; Koichi Hayashi; H Maruyama; Ikuo Saito; Takao Saruta
Effects of intestinal fatty acid-binding protein gene Ala54Thr polymorphism and beta3-adrenergic receptor gene Trp64Arg polymorphism on insulin resistance and fasting plasma glucose in young to older Japanese men.
Metabolism: clinical and experimental 2001;50(11):1301-7.
2001: Masanori Honda; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Hirobumi Tokuyama; Ken Okubo; Ichiro Takamatsu; Yuri Ozawa; Takao Saruta
Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo.
Journal of hypertension 2001;19(11):2031-7.
2001: Masanori Honda; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Hirobumi Tokuyama; Ken Okubo; Yuri Ozawa; Takao Saruta
Divergent natriuretic action of calcium channel antagonists in mongrel dogs: renal haemodynamics as a determinant of natriuresis.
Clinical science (London, England : 1979) 2001;101(4):421-7.
2001: Akihiro Chikaraishi; Junichi Hirahashi; Osamu Takase; Takeshi Marumo; Keiichi Hishikawa; Matsuhiko Hayashi; Takao Saruta
Tranilast inhibits interleukin-1beta-induced monocyte chemoattractant protein-1 expression in rat mesangial cells.
European journal of pharmacology 2001;427(2):151-8.
2001: Hirotaka Shibata; Yayoi Ikeda; T Mukai; K Morohashi; Isao Kurihara; Takashi Ando; Toshihiko Suzuki; Sakiko Kobayashi; Masaru Murai; Ikuo Saito; Takao Saruta
Expression profiles of COUP-TF, DAX-1, and SF-1 in the human adrenal gland and adrenocortical tumors: possible implications in steroidogenesis.
Molecular genetics and metabolism 2001;74(1-2):206-16.
2001: Yuri Ozawa; Koichi Hayashi; Takahiko Nagahama; Keiji Fujiwara; Takao Saruta
Effect of T-type selective calcium antagonist on renal microcirculation: studies in the isolated perfused hydronephrotic kidney.
Hypertension 2001;38(3):343-7.
2001: T Hayashida; Yoichi Ohno; K Otsuka; Taichi Suzawa; K Shibagaki; H Suzuki; H Ikeda; Takao Saruta
Salt-loading elevates blood pressure and aggravates insulin resistance in Wistar fatty rats: a possible role for enhanced Na+ -H+ exchanger activity.
Journal of hypertension 2001;19(9):1643-50.
2001: Izumi Takei; K Miyamoto; Osamu Funae; N Ohashi; Shu Meguro; Mikiya Tokui; Takao Saruta
Secretion of GIP in responders to acarbose in obese Type 2(NIDDM) patients.
Journal of diabetes and its complications 2001;15(5):245-9.
2001: Satoru Yamada; Yoshiko Motohashi; T Yanagawa; Taro Maruyama; Akira Kasuga; Hiroshi Hirose; Koichi Matsubara; Akira Shimada; Takao Saruta
NeuroD/beta2 gene G-->A polymorphism may affect onset pattern of type 1 diabetes in Japanese.
Diabetes care 2001;24(8):1438-41.
2001: Naohito Ishii; Hideki Ikenaga; Zensuke Ogawa; Yoshikazu Aoki; Takao Saruta; T Suga
Effects of renal sorbitol accumulation on urinary excretion of enzymes in hyperglycaemic rats.
Annals of clinical biochemistry 2001;38(Pt 4):391-8.
2001: Y Ohno; H Suzuki; H Yamakawa; M Nakamura; Y Kato; Takao Saruta
Correlation of sodium-related factors with insulin sensitivity in young, lean, male offspring of hypertensive and normotensive subjects.
Journal of human hypertension 2001;15(6):393-9.
2001: Takao Saruta
[The Japanese new guideline for the management of hypertension--background of its preparation and characteristics of the new guideline].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(5):837-40.
2001: Shu Meguro; Izumi Takei; Mitsuru Murata; Hiroshi Hirose; N Takei; Y Mitsuyoshi; Keiko Ishii; Shuji Oguchi; J Shinohara; Eiko Takeshita; Kiyoaki Watanabe; Takao Saruta
Cholesteryl ester transfer protein polymorphism associated with macroangiopathy in Japanese patients with type 2 diabetes.
Atherosclerosis 2001;156(1):151-6.
2001: Tadashi Yoshida; N Yoshida; Toshiaki Monkawa; Matsuhiko Hayashi; Takao Saruta
Dietary phosphorus deprivation induces 25-hydroxyvitamin D(3) 1alpha-hydroxylase gene expression.
Endocrinology 2001;142(5):1720-6.
2001: Mizuo Mifune; Hiroyuki Sasamura; Y Nakazato; Y Yamaji; N Oshima; Takao Saruta
Examination of angiotensin II type 1 and type 2 receptor expression in human kidneys by immunohistochemistry.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2001;23(3):257-66.
2001: Hiromichi Suzuki; Takao Saruta
Effects of calcium antagonist, benidipine, on the progression of chronic renal failure in the elderly: a 1-year follow-up.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2001;23(3):189-201.
2001: Hideaki Nakaya; Hiroyuki Sasamura; Matsuhiko Hayashi; Takao Saruta
Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis.
Journal of the American Society of Nephrology : JASN 2001;12(4):659-66.
2001: Hirohiko Tsuganezawa; K Kobayashi; M Iyori; Takashi Araki; A Koizumi; S Watanabe; A Kaneko; T Fukao; Toshiaki Monkawa; Teruhiko Yoshida; D K Kim; Y Kanai; H Endou; Matsuhiko Hayashi; Takao Saruta
A new member of the HCO3(-) transporter superfamily is an apical anion exchanger of beta-intercalated cells in the kidney.
The Journal of biological chemistry 2001;276(11):8180-9.
2001: Atsuhisa Sato; H Takane; Takao Saruta
High serum level of procollagen type III amino-terminal peptide contributes to the efficacy of spironolactone and angiotensin-converting enzyme inhibitor therapy on left ventricular hypertrophy in essential hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(2):99-104.
2001: Hiroyuki Sasamura; Ryoko Shimizu-Hirota; Hideaki Nakaya; Takao Saruta
Effects of AT1 receptor antagonist on proteoglycan gene expression in hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(2):165-72.
2001: Akira Shimada; Jiro Morimoto; Keiichi Kodama; Ryuji Suzuki; Yoichi Oikawa; Osamu Funae; Akira Kasuga; Takao Saruta; Shosaku Narumi
Elevated serum IP-10 levels observed in type 1 diabetes.
Diabetes care 2001;24(3):510-5.
2001: Atsuhiro Ichihara; Matsuhiko Hayashi; Nobuhisa Hirota; Takao Saruta
Superoxide inhibits neuronal nitric oxide synthase influences on afferent arterioles in spontaneously hypertensive rats.
Hypertension 2001;37(2 Pt 2):630-4.
2001: Hiroshi Hirose; Ikuo Saito; T Kawai; Minako Tsujioka; Hiroshi Kawabe; Takao Saruta
Relationships between baseline serum leptin levels and 2-year changes in body mass index, blood pressure and metabolic parameters in Japanese male adolescents and middle-aged men.
Clinical science (London, England : 1979) 2001;100(2):145-50.
2001: Osamu Funae; Akira Shimada; Mikiya Tokui; Izumi Takei; Takao Saruta
Balance of GAD65-specific IL-10 production and polyclonal Th1-type response in type 1 diabetes.
Autoimmunity 2001;34(1):45-52.
2001: Atsuhisa Sato; Takao Saruta
Aldosterone escape during angiotensin-converting enzyme inhibitor therapy in essential hypertensive patients with left ventricular hypertrophy.
The Journal of international medical research 2001;29(1):13-21.
2001: Toshihide Kawai; Hiroshi Hirose; Y Seto; H Fujita; Takao Saruta
Chronic effects of different fatty acids and leptin in INS-1 cells.
Diabetes research and clinical practice 2001;51(1):1-8.
2000: Hiroyuki Sasamura; Mizuo Mifune; Hideaki Nakaya; T Amemiya; T Hiraki; I Nishimoto; Takao Saruta
Analysis of Galpha protein recognition profiles of angiotensin II receptors using chimeric Galpha proteins.
Molecular and cellular endocrinology 2000;170(1-2):113-21.
2000: Tatsuya Ishii; Hiroshi Hirose; Ikuo Saito; Kanako Nishikai; H Maruyama; Takao Saruta
Tumor necrosis factor alpha gene G-308A polymorphism, insulin resistance, and fasting plasma glucose in young, older, and diabetic Japanese men.
Metabolism: clinical and experimental 2000;49(12):1616-8.
2000: Toshihiko Suzuki; Hirotaka Shibata; Takashi Ando; Isao Kurihara; Sakiko Kobayashi; Koichi Hayashi; Matsuhiko Hayashi; Hiroshi Kawabe; Ikuo Saito; Masaru Murai; Takao Saruta
Risk factors associated with persistent postoperative hypertension in Cushing's syndrome.
Endocrine research 2000;26(4):791-5.
2000: Hirotaka Shibata; Yayoi Ikeda; K Morohashi; T Mukai; Isao Kurihara; Takashi Ando; Toshihiko Suzuki; Sakiko Kobayashi; Koichi Hayashi; Matsuhiko Hayashi; Ikuo Saito; Takao Saruta
Orphan receptors COUP-TF and DAX-1 as targets in disordered CYP17 expression in adrenocortical tumors.
Endocrine research 2000;26(4):1039-44.
2000: Isao Kurihara; Hirotaka Shibata; Toshihiko Suzuki; Takashi Ando; Sakiko Kobayashi; Matsuhiko Hayashi; Ikuo Saito; Takao Saruta
Transcriptional regulation of steroid receptor coactivator-1 (SRC-1) in glucocorticoid action.
Endocrine research 2000;26(4):1033-8.
2000: Y Kato; Matsuhiko Hayashi; Yoichi Ohno; Taichi Suzawa; Takayuki Sasaki; Takao Saruta
Mild renal dysfunction is associated with insulin resistance in chronic glomerulonephritis.
Clinical nephrology 2000;54(5):366-73.
2000: Yoshihiko Kanno; Hirokazu Okada; Takao Saruta; Hiromichi Suzuki
Blood pressure reduction associated with preservation of renal function in hypertensive patients with IgA nephropathy: a 3-year follow-up.
Clinical nephrology 2000;54(5):360-5.
2000: Mizuo Mifune; Hiroyuki Sasamura; Ryoko Shimizu-Hirota; H Miyazaki; Takao Saruta
Angiotensin II type 2 receptors stimulate collagen synthesis in cultured vascular smooth muscle cells.
Hypertension 2000;36(5):845-50.
2000: Hiroshi Kawabe; Hirotaka Shibata; Hiroshi Hirose; Minako Tsujioka; Ikuo Saito; Takao Saruta
Determinants for the development of hypertension in adolescents. A 6-year follow-up.
Journal of hypertension 2000;18(11):1557-61.
2000: Naoki Oshima; Hiroo Kumagai; Akira Kawai; Katsufumi Sakata; Tomokazu Matsuura; Takao Saruta
Three types of putative presympathetic neurons in the rostral ventrolateral medulla studied with rat brainstem-spinal cord preparation.
Autonomic neuroscience : basic & clinical 2000;84(1-2):40-9.
2000: Keiji Fujiwara; Koichi Hayashi; Yuri Ozawa; Hirobumi Tokuyama; A Nakamura; Takao Saruta
Renal protective effect of troglitazone in Wistar fatty rats.
Metabolism: clinical and experimental 2000;49(10):1361-4.
2000: Atsuhiro Ichihara; Matsuhiko Hayashi; L G Navar; Takao Saruta
Inducible nitric oxide synthase attenuates endothelium-dependent renal microvascular vasodilation.
Journal of the American Society of Nephrology : JASN 2000;11(10):1807-12.
2000: S Nakamoto; Akira Kasuga; T Maruyama; Y Ozawa; Shin Amemiya; Takao Saruta
Age of onset, not type of onset, affects the positivity and evanescence of IA-2 antibody.
Diabetes research and clinical practice 2000;50(2):147-52.
2000: Naoki Aikawa; S Suga; Joji Inamasu; J Takeda; T Kawase; Norio Tanahashi; Masaru Murai; Takao Saruta; J Hata
A 35-year-old man with cerebral hemorrhage and pheochromocytoma: the second brain-dead organ donor in Japan.
The Keio journal of medicine 2000;49(3):117-30.
2000: Matsuhiko Hayashi; Y Yamaji; Y Nakazato; Takao Saruta
The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangium cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(5):521-5.
2000: Y Ohno; H Suzuki; H Yamakawa; M Nakamura; Takao Saruta
Insulin sensitivity and calcium homeostasis in young, lean, normotensive male subjects.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(5):433-40.
2000: Hiroshi Hirose; Ikuo Saito; Minako Tsujioka; Hiroshi Kawabe; Takao Saruta
Effects of body weight control on changes in blood pressure: three-year follow-up study in young Japanese individuals.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(5):421-6.
2000: Hiroo Kumagai; Koichi Hayashi; H Kumamaru; Takao Saruta
Amlodipine is comparable to angiotensin-converting enzyme inhibitor for long-term renoprotection in hypertensive patients with renal dysfunction: a one-year, prospective, randomized study.
American journal of hypertension 2000;13(9):980-5.
2000: Toshiaki Monkawa; Tadashi Yoshida; Matsuhiko Hayashi; Takao Saruta
Identification of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression in macrophages.
Kidney international 2000;58(2):559-68.
2000: Matsuhiko Hayashi; Toshiaki Monkawa; Takao Saruta
Cell-specific expression of the IP(3) receptor gene family in the kidney.
Experimental nephrology 2000;8(4-5):215-8.
2000: Yoshihiko Kanno; Hirokazu Okada; T Takenaka; Takao Saruta; Hiromichi Suzuki
Influence of the timing of initiating antihypertensive therapy in hypertensive rats with renal failure.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2000;22(5):521-9.
2000: Takayuki Sasaki; Yoichi Ohno; K Otsuka; Taichi Suzawa; H Suzuki; Takao Saruta
Oestrogen attenuates the increases in blood pressure and platelet aggregation in ovariectomized and salt-loaded Dahl salt-sensitive rats.
Journal of hypertension 2000;18(7):911-7.
2000: Eiji Kikuchi; H Yanaihara; Jun Nakashima; K Homma; Takashi Ohigashi; H Asakura; M Tachibana; H Shibata; Takao Saruta; Masaru Murai
Urinary steroid profile in adrenocortical tumors.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2000;54 Suppl 1():194s-197s.
2000: A Nakamura; Koichi Hayashi; Keiji Fujiwara; Yuri Ozawa; Masanori Honda; Takao Saruta
Distinct action of aranidipine and its active metabolite on renal arterioles, with special reference to renal protection.
Journal of cardiovascular pharmacology 2000;35(6):942-8.
2000: Y Ohno; Hisao Tanase; Toru Nabika; K Otsuka; T Sasaki; T Suzawa; T Morii; Y Yamori; Takao Saruta
Selective genotyping with epistasis can be utilized for a major quantitative trait locus mapping in hypertension in rats.
Genetics 2000;155(2):785-92.
2000: Hiroshi Kawabe; K Murata; Hirotaka Shibata; Hiroshi Hirose; Minako Tsujioka; Ikuo Saito; Takao Saruta
Participation in school sports clubs and related effects on cardiovascular risk factors in young males.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(3):227-32.
2000: T Shigihara; Atsuhisa Sato; Koichi Hayashi; Takao Saruta
Effect of combination therapy of angiotensin-converting enzyme inhibitor plus calcium channel blocker on urinary albumin excretion in hypertensive microalbuminuric patients with type II diabetes.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(3):219-26.
2000: T Morishita; M Nomura; M Hanaoka; Takao Saruta; T Matsuo; Y Tsukamoto
A new assay method that detects only intact osteocalcin. Two-step non-invasive diagnosis to predict adynamic bone disease in haemodialysed patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2000;15(5):659-67.
2000: Takahiko Nagahama; Koichi Hayashi; Keiji Fujiwara; Yuri Ozawa; Takao Saruta
Characterization of the renal action of pranidipine in the rat.
Arzneimittel-Forschung 2000;50(3):248-53.
2000: Junichi Hirahashi; Atsushi Takayanagi; Keiichi Hishikawa; Osamu Takase; Akihiro Chikaraishi; Matsuhiko Hayashi; Nobuyoshi Shimizu; Takao Saruta
Overexpression of truncated I kappa B alpha potentiates TNF-alpha-induced apoptosis in mesangial cells.
Kidney international 2000;57(3):959-68.
2000: Y Tsukamoto; M Hanaoka; T Matsuo; Takao Saruta; M Nomura; Y Takahashi
Effect of 22-oxacalcitriol on bone histology of hemodialyzed patients with severe secondary hyperparathyroidism.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2000;35(3):458-64.
2000: Yumiko Matsubara; Mitsuru Murata; Taro Maruyama; Makoto Handa; N Yamagata; G Watanabe; Takao Saruta; Yasuo Ikeda
Association between diabetic retinopathy and genetic variations in alpha2beta1 integrin, a platelet receptor for collagen.
Blood 2000;95(5):1560-4.
2000: Koichi Hayashi; Takao Saruta
[Experimental models of renal hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 2():703-7.
2000: Hiroo Kumagai; Takao Saruta
[Pituitary disease and hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 2():519-24.
2000: Takao Saruta
[Endocrine hypertension--introduction].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 2():517-8.
2000: Takao Saruta
[Secondary hypertension--introduction].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 2():437-8.
2000: Akira Kasuga; Akira Shimada; Y Ozawa; Taro Maruyama; K Oya; Takao Saruta
IgG1 is the dominant subclass of antibody against glutamic acid decarboxylase among type 1 diabetes in Japanese.
Endocrine journal 2000;47(1):57-62.
2000: Tomoji Mashimo; Toru Nabika; K Kitada; T Serikawa; C Matsumoto; Katsumi Ikeda; Yasuo Nara; Junichi Masuda; Yukio Yamori; Y Ohno; Takao Saruta
Mapping of four simple sequence repeat (SSR) markers on rat chromosome 4.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(1):47-50.
2000: Atsuhisa Sato; Y Suzuki; H Shibata; Takao Saruta
Plasma aldosterone concentrations are not related to the degree of angiotensin-converting enzyme inhibition in essential hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(1):25-31.
2000: Takahiko Nagahama; Koichi Hayashi; Yuri Ozawa; T Takenaka; Takao Saruta
Role of protein kinase C in angiotensin II-induced constriction of renal microvessels.
Kidney international 2000;57(1):215-23.
2000: Toshiaki Monkawa; Isao Kurihara; K Kobayashi; Matsuhiko Hayashi; Takao Saruta
Novel mutations in thiazide-sensitive Na-Cl cotransporter gene of patients with Gitelman's syndrome.
Journal of the American Society of Nephrology : JASN 2000;11(1):65-70.
1999: T Amemiya; Hiroyuki Sasamura; Mizuo Mifune; Y Kitamura; Junichi Hirahashi; Matsuhiko Hayashi; Takao Saruta
Vascular endothelial growth factor activates MAP kinase and enhances collagen synthesis in human mesangial cells.
Kidney international 1999;56(6):2055-63.
1999: N Yoshida; Tadashi Yoshida; A Nakamura; Toshiaki Monkawa; Matsuhiko Hayashi; Takao Saruta
Calcitonin induces 25-hydroxyvitamin D3 1alpha-hydroxylase mRNA expression via protein kinase C pathway in LLC-PK1 cells.
Journal of the American Society of Nephrology : JASN 1999;10(12):2474-9.
1999: Hideaki Nakaya; Hiroyuki Sasamura; Y Kitamura; T Amemiya; K Konishi; Matsuhiko Hayashi; Takao Saruta
Effects of angiotensin inhibitors on renal injury and angiotensin receptor expression in early hypertensive nephrosclerosis.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(4):303-12.
1999: Hiroto Matsuda; Koichi Hayashi; Kikuo Arakawa; M Naitoh; Eiji Kubota; Masanori Honda; A Matsumoto; Hiromichi Suzuki; Tokunori Yamamoto; Fumihiko Kajiya; Takao Saruta
Zonal heterogeneity in action of angiotensin-converting enzyme inhibitor on renal microcirculation: role of intrarenal bradykinin.
Journal of the American Society of Nephrology : JASN 1999;10(11):2272-82.
1999: Matsuhiko Hayashi; Toshiaki Monkawa; Tadashi Yoshida; Hiroyuki Sasamura; M Matsumoto; takafumi inoue; Katsuhiko Mikoshiba; Takao Saruta
Intracellular calcium concentration in the inositol trisphosphate receptor type 1 knockout mouse.
Journal of the American Society of Nephrology : JASN 1999;10(10):2094-101.
1999: Takao Saruta; Kikuo Arakawa; O Iimura; K Abe; H Matsuoka; T Nakano; M Nakagawa; Toshio Ogihara; G Kajiyama; Kunio Hiwada; M Fujishima; M Nakajima
Difference in the incidence of cough induced by angiotensin converting enzyme inhibitors: a comparative study using imidapril hydrochloride and enalapril maleate.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(3):197-202.
1999: Hiroshi Kawabe; Hirotaka Shibata; Hiroshi Hirose; Minako Tsujioka; Ikuo Saito; Takao Saruta
Sexual differences in relationships between birth weight or current body weight and blood pressure or cholesterol in young Japanese students.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(3):169-72.
1999: Atsuhisa Sato; J W Funder; Takao Saruta
Involvement of aldosterone in left ventricular hypertrophy of patients with end-stage renal failure treated with hemodialysis.
American journal of hypertension 1999;12(9 Pt 1):867-73.
1999: Toshihide Kawai; Izumi Takei; Yuko Oguma; N Ohashi; Mikiya Tokui; Shuji Oguchi; Fuminori Katsukawa; Hiroshi Hirose; Akira Shimada; Kiyoaki Watanabe; Takao Saruta
Effects of troglitazone on fat distribution in the treatment of male type 2 diabetes.
Metabolism: clinical and experimental 1999;48(9):1102-7.
1999: H Suzuki; M Nishizawa; M Ichikawa; K Kumagai; M Ryuzaki; H Kumagai; Takao Saruta; H Ikeda
Basal sympathetic nerve activity is enhanced with augmentation of baroreceptor reflex in Wistar fatty rats: a model of obesity-induced NIDDM.
Journal of hypertension 1999;17(7):959-64.
1999: Atsuhiro Ichihara; H Suzuki; Y Miyashita; M Naitoh; Matsuhiko Hayashi; Takao Saruta
Transmural pressure inhibits prorenin processing in juxtaglomerular cell.
The American journal of physiology 1999;277(1 Pt 2):R220-8.
1999: Keiji Fujiwara; Koichi Hayashi; Hiroto Matsuda; Eiji Kubota; Masanori Honda; Yuri Ozawa; Takao Saruta
Altered pressure-natriuresis in obese Zucker rats.
Hypertension 1999;33(6):1470-5.
1999: Koichi Hayashi; H Matsuda; M Honda; Takao Saruta
[Potential role of angiotensin receptor antagonists in renal protection].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(5):1164-7.
1999: Ikuo Saito; Takao Saruta
[Angiotensin II receptor antagonists: a review of the development and future perspective].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(5):1015-9.
1999: Tadashi Yoshida; N Yoshida; A Nakamura; Toshiaki Monkawa; Matsuhiko Hayashi; Takao Saruta
Cloning of porcine 25-hydroxyvitamin D3 1alpha-hydroxylase and its regulation by cAMP in LLC-PK1 cells.
Journal of the American Society of Nephrology : JASN 1999;10(5):963-70.
1999: T Araki; Takao Saruta; Hideyuki Okano; M Miura
Caspase activity is required for nephrogenesis in the developing mouse metanephros.
Experimental cell research 1999;248(2):423-9.
1999: Koichi Hayashi; Hiroto Matsuda; Takahiko Nagahama; Keiji Fujiwara; Yuri Ozawa; Eiji Kubota; Masanori Honda; Hirobumi Tokuyama; Takao Saruta
Impaired nitric oxide-independent dilation of renal afferent arterioles in spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(1):31-7.
1999: Atsuhisa Sato; Y Suzuki; Takao Saruta
Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(1):17-22.
1999: H Nakamoto; H Suzuki; A Ohishi; H Katsumata; H Sakaguchi; Takao Saruta
Effects of cicletanine on the progression of renal failure in 5/6 nephrectomized hypertensive rats.
Clinical and experimental pharmacology & physiology 1999;26(3):236-41.
1999: Hiroshi Hirose; Ikuo Saito; Takao Saruta
Supplement. Obesity, hypertension, insulin resistance and lipid disorders: cross-sectional and longitudinal studies in Japanese adolescents and middle-aged men.
Internal medicine (Tokyo, Japan) 1999;38(2):198-200.
1999: Yuri Ozawa; Koichi Hayashi; Takahiko Nagahama; Keiji Fujiwara; Shu Wakino; Takao Saruta
Renal afferent and efferent arteriolar dilation by nilvadipine: studies in the isolated perfused hydronephrotic kidney.
Journal of cardiovascular pharmacology 1999;33(2):243-7.
1999: Junichi Hirahashi; Toshio Nakaki; Keiichi Hishikawa; Takeshi Marumo; Matsuhiko Hayashi; Takao Saruta
Endothelin ET(A) receptor antagonist reverses the inhibitory effect of platelet-derived growth factor on cytokine-induced nitric oxide production.
European journal of pharmacology 1999;365(1):119-23.
1999: K Konishi; Takao Saruta; Shigeru Kuramochi; S Oikawa; T Saito; H Han; Akira Matsunaga; J Sasaki
Association of a novel 3-amino acid deletion mutation of apolipoprotein E (Apo E Tokyo) with lipoprotein glomerulopathy.
Nephron 1999;83(3):214-8.
1999: T Yanagawa; T Maruyama; K Gomi; Matsuo Taniyama; A Kasuga; Y Ozawa; M Terauchi; H Hirose; H Maruyama; Takao Saruta
Lack of association between CTLA-4 gene polymorphism and IDDM in Japanese subjects.
Autoimmunity 1999;29(1):53-6.
1999: Hiroyuki Kobori; Atsuhiro Ichihara; Y Miyashita; Matsuhiko Hayashi; Takao Saruta
Local renin-angiotensin system contributes to hyperthyroidism-induced cardiac hypertrophy.
The Journal of endocrinology 1999;160(1):43-7.
1998: T Ando; Akihiro Umezawa; Atsushi Suzuki; Hajime Okita; Makoto Sano; Y Hiraoka; S Aiso; Takao Saruta; Jun-ichi Hata
EAT/mcl-1, a member of the bcl-2 related genes, confers resistance to apoptosis induced by cis-diammine dichloroplatinum (II) via a p53-independent pathway.
Japanese journal of cancer research : Gann 1998;89(12):1326-33.
1998: Hiroshi Hirose; Ikuo Saito; Minako Tsujioka; Masaaki Mori; Hiroshi Kawabe; Takao Saruta
The obese gene product, leptin: possible role in obesity-related hypertension in adolescents.
Journal of hypertension 1998;16(12 Pt 2):2007-12.
1998: Hirotaka Shibata; Takashi Ando; Toshihiko Suzuki; Isao Kurihara; Koichi Hayashi; Matsuhiko Hayashi; Ikuo Saito; Masaru Murai; Takao Saruta
COUP-TFI expression in human adrenocortical adenomas: possible role in steroidogenesis.
The Journal of clinical endocrinology and metabolism 1998;83(12):4520-3.
1998: Y Kitamura; Hiroyuki Sasamura; Hideaki Nakaya; T Maruyama; Matsuhiko Hayashi; Takao Saruta
Effects of ACTH on adrenal angiotensin II receptor subtype expression in vivo.
Molecular and cellular endocrinology 1998;146(1-2):187-95.
1998: Tadashi Yoshida; Toshiaki Monkawa; Harriet S Tenenhouse; Paul Goodyer; Toshimasa Shinki; Toshio Suda; Shu Wakino; Matsuhiko Hayashi; Takao Saruta
Two novel 1alpha-hydroxylase mutations in French-Canadians with vitamin D dependency rickets type I1.
Kidney international 1998;54(5):1437-43.
1998: Jiro Morimoto; Taro Maruyama; Akira Kasuga; Y Ozawa; A Kobayashi; S Funakoshi; R Iwasaki; Y Suzuki; Akira Shimada; Takao Saruta
Three cases of GAD65 antibody-positive diabetes with ketosis and abrupt onset resulting in non-insulin-dependent state.
Diabetes care 1998;21(11):2037-9.
1998: Hiroyuki Kobori; Atsuhiro Ichihara; Y Miyashita; Matsuhiko Hayashi; Takao Saruta
Mechanism of hyperthyroidism-induced renal hypertrophy in rats.
The Journal of endocrinology 1998;159(1):9-14.
1998: Y Kitamura; Hiroyuki Sasamura; T Maruyama; Hideaki Nakaya; T Amemiya; Matsuhiko Hayashi; Takao Saruta
Adrenal angiotensin II type 1 and type 2 receptors in Cushing's and Conn's syndromes.
Molecular and cellular endocrinology 1998;144(1-2):37-45.
1998: Y Ozawa; H Maruyama; S Nakano; Takao Saruta
An unconscious diabetic patient.
Postgraduate medical journal 1998;74(875):549-50.
1998: T Takenaka; H Suzuki; H Okada; K Hayashi; Y Kanno; Takao Saruta
Mechanosensitive cation channels mediate afferent arteriolar myogenic constriction in the isolated rat kidney.
The Journal of physiology 1998;511 ( Pt 1)():245-53.
1998: Takashi Ando; Hirotaka Shibata; Toshihiko Suzuki; Isao Kurihara; Koichi Hayashi; Matsuhiko Hayashi; Ikuo Saito; Hiroshi Kawabe; Minako Tsujioka; Takao Saruta
The possible role of apoptosis-suppressing genes, bcl-2 and mcl-1/EAT in human adrenal tumors.
Endocrine research 1998;24(3-4):955-60.
1998: Hirotaka Shibata; Takashi Ando; Toshihiko Suzuki; Isao Kurihara; Koichi Hayashi; Matsuhiko Hayashi; Ikuo Saito; Hiroshi Kawabe; Minako Tsujioka; M Mural; Takao Saruta
Differential expression of an orphan receptor COUP-TFI and corepressors in adrenal tumors.
Endocrine research 1998;24(3-4):881-5.
1998: Y Nakazato; T Hayashida; Y Kanno; Hiroyuki Sasamura; H Okada; H Suzuki; Takao Saruta
Interleukin (IL)-1 and IL-4 synergistically stimulate NF-IL6 activity and IL-6 production in human mesangial cells.
Kidney international 1998;54(1):71-9.
1998: Hiroshi Hirose; Ikuo Saito; T Kawai; K Nakamura; H Maruyama; Takao Saruta
Serum leptin level: possible association with haematopoiesis in adolescents, independent of body mass index and serum insulin.
Clinical science (London, England : 1979) 1998;94(6):633-6.
1998: K Ito; T Wada; H Makimura; A Matsuoka; H Maruyama; Takao Saruta
Vector autoregressive modeling analysis of frequently sampled oral glucose tolerance test results. 2. Insulin resistance and secretion after gastrectomy.
The Keio journal of medicine 1998;47(2):78-84.
1998: Y Ozawa; Toru Kameya; Akira Kasuga; Heiji Naritaka; N Kanda; H Maruyama; Takao Saruta
A functional thyrotropin- and growth hormone-secreting pituitary adenoma with a ultrastructurally monomorphic feature: a case study.
Endocrine journal 1998;45(2):211-9.
1998: Keiji Fujiwara; Y Kanno; Koichi Hayashi; T Takenaka; Takao Saruta
Renal protective effects of efonidipine in partially nephrectomized spontaneously hypertensive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1998;20(3):295-312.
1998: T Yoshida; N Momotani; Matsuhiko Hayashi; Toshiaki Monkawa; K Ito; Takao Saruta
Serum leptin concentrations in patients with thyroid disorders.
Clinical endocrinology 1998;48(3):299-302.
1998: Izumi Takei; S Takayama; A Yamauchi; S Nakamoto; Y Kitamura; Fuminori Katsukawa; Hajime Yamazaki; Takao Saruta; S Inoue
Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure: a preliminary report.
European journal of clinical nutrition 1998;52(2):153-4.
1998: Atsuhiro Ichihara; Hiroyuki Kobori; Y Miyashita; Matsuhiko Hayashi; Takao Saruta
Differential effects of thyroid hormone on renin secretion, content, and mRNA in juxtaglomerular cells.
The American journal of physiology 1998;274(2 Pt 1):E224-31.
1998: Toshiaki Monkawa; Matsuhiko Hayashi; A Miyawaki; T Sugiyama; Miki Yamamoto-Hino; M Hasegawa; Teiichi Furuichi; Katsuhiko Mikoshiba; Takao Saruta
Localization of inositol 1,4,5-trisphosphate receptors in the rat kidney.
Kidney international 1998;53(2):296-301.
1997: T Yanagawa; Matsuo Taniyama; S Enomoto; K Gomi; H Maruyama; Y Ban; Takao Saruta
CTLA4 gene polymorphism confers susceptibility to Graves' disease in Japanese.
Thyroid : official journal of the American Thyroid Association 1997;7(6):843-6.
1997: Hiroyuki Sasamura; L Hein; Takao Saruta; R E Pratt
Evidence for internalization of both type 1 angiotensin receptor subtypes (AT1a, AT1b) by a protein kinase C independent mechanism.
Hypertension research : official journal of the Japanese Society of Hypertension 1997;20(4):295-300.
1997: K Otsuka; Yoichi Ohno; Takayuki Sasaki; H Yamakawa; T Hayashida; Taichi Suzawa; H Suzuki; Takao Saruta
Ovariectomy aggravated sodium induced hypertension associated with altered platelet intracellular Ca2+ in Dahl rats.
American journal of hypertension 1997;10(12 Pt 1):1396-403.
1997: M Murakami; Hiroto Matsuda; Eiji Kubota; Shu Wakino; Masanori Honda; Koichi Hayashi; Takao Saruta
Role of angiotensin II generated by angiotensin converting enzyme-independent pathways in canine kidney.
Kidney international. Supplement 1997;63():S132-5.
1997: Toshimasa Shinki; H Shimada; Shu Wakino; H Anazawa; Matsuhiko Hayashi; Takao Saruta; Hector F Deluca; Toshio Suda
Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):12920-5.
1997: Toshiaki Monkawa; Tadashi Yoshida; Shu Wakino; Toshimasa Shinki; H Anazawa; Hector F Deluca; Toshio Suda; Matsuhiko Hayashi; Takao Saruta
Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1 alpha-hydroxylase.
Biochemical and biophysical research communications 1997;239(2):527-33.
1997: K Koyama; H Maruyama; Takao Saruta
[Rhabdomyolysis in the diabetic state].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():1016-20.
1997: K Oka; Koichi Hayashi; T Nakazato; Taichi Suzawa; K Fujiwara; Takao Saruta
Malignant hypertension in a patient with primary aldosteronism with elevated active renin concentration.
Internal medicine (Tokyo, Japan) 1997;36(10):700-4.
1997: Hiroshi Hirose; Y Seto; H Maruyama; K Dan; K Nakamura; Takao Saruta
Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells.
Metabolism: clinical and experimental 1997;46(10):1146-9.
1997: Akira Kasuga; Y Ozawa; Taro Maruyama; T Ishihara; Shin Amemiya; Takao Saruta
Autoantibody against IA-2 improves the test sensitivity for insulin-dependent diabetes mellitus in Japanese patients of child onset.
Endocrine journal 1997;44(4):485-91.
1997: N Arata; N Momotani; H Maruyama; Takao Saruta; K Tsukatani; Atsushi Kubo; K Ikemoto; K Ito
Bone mineral density after surgical treatment for Graves' disease.
Thyroid : official journal of the American Thyroid Association 1997;7(4):547-54.
1997: Ikuo Saito; Takao Saruta
[Large, long-term, randomized trials and meta-analysis of therapy of patients with hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(8):2086-90.
1997: Hiroo Kumagai; Takao Saruta
[Renal function and hemodynamics in hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(8):1999-2004.
1997: Hiroyuki Kobori; Atsuhiro Ichihara; Hidekazu Suzuki; T Takenaka; Y Miyashita; Matsuhiko Hayashi; Takao Saruta
Role of the renin-angiotensin system in cardiac hypertrophy induced in rats by hyperthyroidism.
The American journal of physiology 1997;273(2 Pt 2):H593-9.
1997: Hiroyuki Sasamura; Y Nakazato; T Hayashida; Y Kitamura; Matsuhiko Hayashi; Takao Saruta
Regulation of vascular type 1 angiotensin receptors by cytokines.
Hypertension 1997;30(1 Pt 1):35-41.
1997: T Yanagawa; Y Yoshida; N Wada; E Nakao; H Ogiwara; I Uyama; T Takahara; T Nomura; K Gomi; Takao Saruta
Blood pressure, insulin, and haematocrit values in Japanese subjects over 60 years of age.
Journal of human hypertension 1997;11(6):355-9.
1997: Koichi Hayashi; Keiji Fujiwara; K Oka; Takahiko Nagahama; H Matsuda; Takao Saruta
Effects of insulin on rat renal microvessels: studies in the isolated perfused hydronephrotic kidney.
Kidney international 1997;51(5):1507-13.
1997: Mikiya Tokui; Izumi Takei; Fumi Tashiro; Akira Shimada; Akira Kasuga; M Ishii; T Ishii; Kiyoshi Takatsu; Takao Saruta; J i Miyazaki
Intramuscular injection of expression plasmid DNA is an effective means of long-term systemic delivery of interleukin-5.
Biochemical and biophysical research communications 1997;233(2):527-31.
1997: Y Kanno; H Suzuki; H Okada; Y Nakazato; Takao Saruta
Retroviral infection in peripheral mononuclear cells in patients with IgA nephropathy.
Clinical nephrology 1997;47(4):211-6.
1997: Tadashi Yoshida; Toshiaki Monkawa; Matsuhiko Hayashi; Takao Saruta
Regulation of expression of leptin mRNA and secretion of leptin by thyroid hormone in 3T3-L1 adipocytes.
Biochemical and biophysical research communications 1997;232(3):822-6.
1997: Hiroo Kumagai; Hiromichi Suzuki; M Ichikawa; M Nishizawa; Naoki Oshima; Takao Saruta
Interaction between endothelin and nitric oxide in sympathetic nerve modulation in hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 1997;20(1):35-42.
1997: Yoichi Ohno; Koichi Matsuo; H Suzuki; H Tanase; T Takano; Takao Saruta
Increased intracellular Ca2+ is not coinherited with an inferred major gene locus for hypertension (ht) in the spontaneously hypertensive rat.
American journal of hypertension 1997;10(3):282-8.
1997: T Maruyama; Akira Kasuga; Y Ozawa; A Nagata; F Abiko; Y Suzuki; Takao Saruta
Glutamic acid decarboxylase65 (GAD65) antibodies and insulin auto-antibodies in Japanese patients with non-insulin-dependent diabetes mellitus.
Endocrine journal 1997;44(1):43-51.
1997: M Naitoh; Hidekazu Suzuki; Kikuo Arakawa; A Matsumoto; Atsuhiro Ichihara; H Matsuda; E Kubota; M Murakami; H Nakamoto; Takao Saruta
Role of kinin and renal ANG II blockade in acute effects of ACE inhibitors in low-renin hypertension.
The American journal of physiology 1997;272(2 Pt 2):H679-87.
1997: Hiroyuki Kobori; Atsuhiro Ichihara; Hidekazu Suzuki; Y Miyashita; Matsuhiko Hayashi; Takao Saruta
Thyroid hormone stimulates renin synthesis in rats without involving the sympathetic nervous system.
The American journal of physiology 1997;272(2 Pt 1):E227-32.
1997: A Yamauchi; Izumi Takei; Z Makita; S Nakamoto; N Ohashi; H Kiguchi; T Ishii; T Koike; Takao Saruta
Effects of aminoguanidine on serum advanced glycation endproducts, urinary albilmin excretion, mesangial expansion, and glomerular basement membrane thickening in Otsuka Long-Evans Tokushima fatty rats.
Diabetes research and clinical practice 1997;34(3):127-33.
1997: Matsuhiko Hayashi; Y Yamaji; Toshiaki Monkawa; Teruhiko Yoshida; Hirohiko Tsuganezawa; Hiroyuki Sasamura; W Kitajima; S Sasaki; K Ishibashi; F Maurmo; Takao Saruta
Expression and localization of the water channels in human autosomal dominant polycystic kidney disease.
Nephron 1997;75(3):321-6.
1997: Matsuhiko Hayashi; Tadashi Yoshida; Toshiaki Monkawa; Y Yamaji; S Sato; Takao Saruta
Na+/H+-exchanger 3 activity and its gene in the spontaneously hypertensive rat kidney.
Journal of hypertension 1997;15(1):43-8.
1997: M Nishizawa; Hiroo Kumagai; M Ichikawa; Naoki Oshima; Hiromichi Suzuki; Takao Saruta
Improvement in baroreflex function by an oral angiotensin receptor antagonist in rats with myocardial infarction.
Hypertension 1997;29(1 Pt 2):458-63.
1996: Y Ozawa; Akira Kasuga; T Maruyama; Y Kitamura; Shin Amemiya; T Ishihara; R Suzuki; Takao Saruta
Antibodies to the 37,000-Mr tryptic fragment of islet antigen were detected in Japanese insulin-dependent diabetes mellitus patients.
Endocrine journal 1996;43(6):615-20.
1996: Koichi Hayashi; Murray Epstein; Takao Saruta
Altered myogenic responsiveness of the renal microvasculature in experimental hypertension.
Journal of hypertension 1996;14(12):1387-401.
1996: T Yoshida; M Hayashi; Toshiaki Monkawa; Takao Saruta
Regulation of obese mRNA expression by hormonal factors in primary cultures of rat adipocytes.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(5):619-25.
1996: Yoichi Ohno; Koichi Matsuo; H Suzuki; H Tanase; T Serikawa; T Takano; Takao Saruta
Genetic linkage of the sarco(endo)plasmic reticulum Ca(2+)-dependent ATPase II gene to intracellular Ca2+ concentration in the spontaneously hypertensive rat.
Biochemical and biophysical research communications 1996;227(3):789-93.
1996: J Hirahashi; Toshio Nakaki; K Hishikawa; T Marumo; T Yasumori; M Hayashi; H Suzuki; Takao Saruta
Endothelin-1 inhibits induction of nitric oxide synthase and GTP cyclohydrolase I in rat mesangial cells.
Pharmacology 1996;53(4):241-9.
1996: Y Ozawa; Akira Kasuga; H Nomaguchi; T Maruyama; T Kasatani; Akira Shimada; Izumi Takei; J Miyazaki; Takao Saruta
Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus.
Journal of autoimmunity 1996;9(4):517-24.
1996: K Hishikawa; Toshio Nakaki; J Hirahashi; T Marumo; Takao Saruta
Tranilast restores cytokine-induced nitric oxide production against platelet-derived growth factor in vascular smooth muscle cells.
Journal of cardiovascular pharmacology 1996;28(2):200-7.
1996: Akira Kasuga; Alberto Falorni; T Maruyama; Y Ozawa; C E Grubin; K Matsubara; Izumi Takei; Takao Saruta; A Scheynius; Ake Lernmark
HLA class II is associated with the frequency of glutamic acid decarboxylase M(r) 65,000 autoantibodies in Japanese patients with insulin-dependent diabetes mellitus.
Acta diabetologica 1996;33(2):108-13.
1996: A Yamauchi; Izumi Takei; Akira Kasuga; Y Kitamura; N Ohashi; S Nakano; S Takayama; S Nakamoto; Fuminori Katsukawa; Takao Saruta
Depression of dehydroepiandrosterone in Japanese diabetic men--comparison between non-insulin-dependent diabetes mellitus and impaired glucose tolerance.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(1):101-4.
1996: I Saito; H Kawabe; E Takeshita; H Wainai; K Murata; Takao Saruta
Insulin resistance syndrome in adolescents and adults.
Hypertension research : official journal of the Japanese Society of Hypertension 1996;19 Suppl 1():S19-22.
1996: A Yamauchi; Izumi Takei; S Nakamoto; N Ohashi; Y Kitamura; Mikiya Tokui; S Nakano; S Takayama; Akira Kasuga; Fuminori Katsukawa; Takao Saruta
Hyperglycemia decreases dehydroepiandrosterone in Japanese male with impaired glucose tolerance and low insulin response.
Endocrine journal 1996;43(3):285-90.
1996: Akira Kasuga; H Maruyama; T Sato; S Nogawa; H Mitamura; Takao Saruta
Myasthenia-like syndrome induced by overdosage of cibenzoline.
Internal medicine (Tokyo, Japan) 1996;35(6):512-4.
1996: Takao Saruta; Y Kanno; Koichi Hayashi; K Konishi
Antihypertensive agents and renal protection: calcium channel blockers.
Kidney international. Supplement 1996;55():S52-6.
1996: A Yamauchi; K Amano; Y Ichikawa; S Nakamoto; I Takei; H Maruyama; N Kono; Takao Saruta
McArdle's disease with non-insulin-dependent diabetes mellitus: the beneficial effects of hyperglycemia and hyperinsulinemia for exercise intolerance.
Internal medicine (Tokyo, Japan) 1996;35(5):403-6.
1996: Kikuo Arakawa; H Suzuki; M Naitoh; A Matsumoto; Koichi Hayashi; Hiroto Matsuda; Atsuhiro Ichihara; E Kubota; Takao Saruta
Role of adenosine in the renal responses to contrast medium.
Kidney international 1996;49(5):1199-206.
1996: Koichi Hayashi; Takahiko Nagahama; K Oka; Murray Epstein; Takao Saruta
Disparate effects of calcium antagonists on renal microcirculation.
Hypertension research : official journal of the Japanese Society of Hypertension 1996;19(1):31-6.
1996: Takao Saruta
Mechanism of glucocorticoid-induced hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 1996;19(1):1-8.
1996: Y Nakazato; H Okada; S Tajima; T Hayashida; Y Kanno; H Suzuki; Takao Saruta
Interleukin-4 modulates collagen synthesis by human mesangial cells in a type-specific manner.
The American journal of physiology 1996;270(3 Pt 2):F447-53.
1996: Yoichi Ohno; Koichi Matsuo; H Suzuki; H Tanase; H Ikeshima; T Takano; Takao Saruta
Genotypes of sarco(endo)plasmic reticulum Ca(2+)-dependent ATPase II gene in substrains of spontaneously hypertensive rats.
Journal of hypertension 1996;14(3):287-91.
1996: Y Kanno; H Okada; H Suzuki; H Ikenaga; N Ishii; H Itoh; Takao Saruta
Does combined therapy of Ca-channel blocker and angiotensin converting enzyme inhibitor exceed monotherapy in renal protection against hypertensive injury in rats?
Clinical and experimental hypertension (New York, N.Y. : 1993) 1996;18(2):243-56.
1996: Akira Kasuga; T Maruyama; Y Ozawa; Izumi Takei; Alberto Falorni; A Lernmark; Takao Saruta
Antibody to the M(r) 65,000 isoform of glutamic acid decarboxylase are detected in non-insulin-dependent diabetes in Japanese.
Journal of autoimmunity 1996;9(1):105-11.
1996: Koichiro Kumagai; H Suzuki; M Ichikawa; Masahito Jimbo; M Nishizawa; M Ryuzaki; Takao Saruta
Comparison of early and late start of antihypertensive agents and baroreceptor reflexes.
Hypertension 1996;27(2):209-18.
1996: Akira Shimada; T Kasatani; Izumi Takei; T Maruyama; H Nomaguchi; Y Ozawa; M Ishii; Akira Kasuga; Fumi Tashiro; J Miyazaki; K Yamamura; Takao Saruta
Immune response to heat-shock protein correlates with induction of insulitis in I-E alpha d transgenic NOD mice.
Diabetes 1996;45(2):165-9.
1996: Shu Wakino; M Meguro; H Suzuki; Takao Saruta; T Ogishima; H Shimada; Yuzuru Ishimura; Toshimasa Shinki; Toshio Suda
Evidence for 54-kD protein in chicken kidney as a cytochrome P450 with a high molecular activity of 25-hydroxyvitamin D3 1 alpha-hydroxylase.
Gerontology 1996;42 Suppl 1():67-77.
1996: M Hayashi; S Sasaki; Hirohiko Tsuganezawa; Toshiaki Monkawa; W Kitajima; K Konishi; K Fushimi; F Marumo; Takao Saruta
Role of vasopressin V2 receptor in acute regulation of aquaporin-2.
Kidney & blood pressure research 1996;19(1):32-7.
1996: H Okada; H Suzuki; Y Kanno; Takao Saruta
Evidence for the involvement of vasopressin in the pathophysiology of adriamycin-induced nephropathy in rats.
Nephron 1996;72(4):667-72.
1996: Y Kanno; H Suzuki; H Okada; T Takenaka; Takao Saruta
Calcium channel blockers versus ACE inhibitors as antihypertensives in polycystic kidney disease.
QJM : monthly journal of the Association of Physicians 1996;89(1):65-70.
1996: K Otsuka; H Suzuki; T Sasaki; N Ishii; H Itoh; Takao Saruta
Blunted pressure natriuresis in ovariectomized Dahl-Iwai salt-sensitive rats.
Hypertension 1996;27(1):119-24.
1995: M Ichikawa; H Suzuki; Koichiro Kumagai; M Ryuzaki; Hiroo Kumagai; M Nishizawa; Takao Saruta
Baroreceptor function is restored by antihypertensive therapy through lowering of blood pressure in adult SHR.
Clinical and experimental pharmacology & physiology. Supplement 1995;22(1):S67-9.
1995: Yoichi Ohno; H Suzuki; Koichi Matsuo; H Tanase; T Takano; Takao Saruta
Augmented Ca2+ mobilization is a hypertensive trait discriminated from a 'major gene' in backcross analysis between SHR and Donryu rats.
Clinical and experimental pharmacology & physiology. Supplement 1995;22(1):S220-2.
1995: M Murakami; H Suzuki; M Naitoh; A Matsumoto; Y Kageyama; G Tsujimoto; Takao Saruta
Blockade of the renin-angiotensin system in heart failure in conscious dogs.
Journal of hypertension 1995;13(12 Pt 1):1405-12.
1995: K Ito; Hiroshi Hirose; K Kido; K Koyama; H Maruyama; Takao Saruta
Adrenoceptor antagonists, but not guanethidine, reduce glucopenia-induced glucagon secretion from perfused rat pancreas.
Diabetes research and clinical practice 1995;30(3):173-80.
1995: Takao Saruta; T Tominaga; H Yamakawa; Yoichi Ohno; H Suzuki
Blood pressure sensitivity to salt, calcium metabolism and insulin sensitivity in essential hypertension.
Clinical and experimental pharmacology & physiology 1995;22(12):S406-11.
1995: A Ohishi; H Suzuki; H Nakamoto; H Katsumata; K Hayashi; M Ryuzaki; K Kumagai; T Furukawa; Atsuhiro Ichihara; Takao Saruta
Status of patients who underwent uninephrectomy in adulthood more than 20 years ago.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1995;26(6):889-97.
1995: Hirotaka Shibata; H Suzuki; T Maruyama; Takao Saruta
Gene expression of angiotensin II receptor in blood cells of Cushing's syndrome.
Hypertension 1995;26(6 Pt 1):1003-10.
1995: K Hishikawa; Toshio Nakaki; J Hirahashi; T Marumo; Takao Saruta
Tranilast inhibits the effects of platelet-derived growth factor on cell proliferation and induction of nitric oxide.
European journal of pharmacology 1995;291(3):435-8.
1995: K Ito; H Hirose; H Maruyama; S Fukamachi; Y Tashiro; Takao Saruta
Neurotransmitters partially restore glucose sensitivity of insulin and glucagon secretion from perfused streptozotocin-induced diabetic rat pancreas.
Diabetologia 1995;38(11):1276-84.
1995: Atsuhiro Ichihara; H Suzuki; M Murakami; M Naitoh; A Matsumoto; Takao Saruta
Interactions between angiotensin II and norepinephrine on renin release by juxtaglomerular cells.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(5):569-77.
1995: Hirotaka Shibata; H Suzuki; T Maruyama; K Murata; Takao Saruta
Effect of dietary chloride on aldosterone synthase induction and angiotensin II receptors in rat adrenals.
Molecular and cellular endocrinology 1995;114(1-2):167-75.
1995: H Okada; H Suzuki; Y Kanno; H Ikenaga; Takao Saruta
Renal responses to angiotensin receptor antagonist and angiotensin-converting enzyme inhibitor in partially nephrectomized spontaneously hypertensive rats.
Journal of cardiovascular pharmacology 1995;26(4):564-9.
1995: Takao Saruta; T Omae; M Kuramochi; O Iimura; K Yoshinaga; K Abe; M Ishii; T Watanabe; T Takeda; K Ito
Imidapril hydrochloride in essential hypertension: a double-blind comparative study using enalapril maleate as a control.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1995;13(3):523-30.
1995: Izumi Takei; A Yamauchi; S Nakamoto; H Suzuki; Takao Saruta
Retrospective analysis of hemodialyzed diabetic patients in Japan.
Diabetes research and clinical practice 1995;29(3):173-7.
1995: M Ichikawa; H Suzuki; Koichiro Kumagai; Hiroo Kumagai; M Ryuzaki; M Nishizawa; Takao Saruta
Differential modulation of baroreceptor sensitivity by long-term antihypertensive treatment.
Hypertension 1995;26(3):425-31.
1995: H Kawabe; O U Lopes; K Bridget Brosnihan; Takao Saruta; Carlos M Ferrario
Angiotensin II pressor activity depends on medial and lateral anterior hypothalamic pathways.
Angiology 1995;46(8):641-8.
1995: A Sato; J W Funder; M Okubo; E Kubota; Takao Saruta
Glucocorticoid-induced hypertension in the elderly. Relation to serum calcium and family history of essential hypertension.
American journal of hypertension 1995;8(8):823-8.
1995: Toshiaki Monkawa; Atsushi Miyawaki; Takao Sugiyama; H Yoneshima; Miki Yamamoto-Hino; Teiichi Furuichi; Takao Saruta; M Hasegawa; K Mikoshiba
Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits.
The Journal of biological chemistry 1995;270(24):14700-4.
1995: M Nakamura; H Suzuki; Yoichi Ohno; A Ohishi; H Yamakawa; H Okada; Takao Saruta
Oral calcium carbonate administration ameliorates the progression of renal failure in rats with hypertension.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1995;25(6):910-7.
1995: Koichi Hayashi; H Suzuki; Takao Saruta
Nitric oxide modulates but does not impair myogenic vasoconstriction of the afferent arteriole in spontaneously hypertensive rats. Studies in the isolated perfused hydronephrotic kidney.
Hypertension 1995;25(6):1212-9.
1995: H Okada; H Suzuki; Y Kanno; Takao Saruta
Effects of novel, nonpeptide vasopressin antagonists on progressive nephrosclerosis in rats.
Journal of cardiovascular pharmacology 1995;25(5):847-52.
1995: T Marumo; Toshio Nakaki; K Hishikawa; J Hirahashi; H Suzuki; R Kato; Takao Saruta
Natriuretic peptide-augmented induction of nitric oxide synthase through cyclic guanosine 3',5'-monophosphate elevation in vascular smooth muscle cells.
Endocrinology 1995;136(5):2135-42.
1995: H Okada; H Suzuki; Y Kanno; Takao Saruta
Effect of nonpeptide vasopressin receptor antagonists on developing, and established DOCA-salt hypertension in rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1995;17(3):469-83.
1995: Akira Kasuga; Toshio Nakaki; Izumi Takei; S Takayama; Y Ozawa; T Maruyama; J Miyazaki; Takao Saruta
Nitric oxide is important for mouse beta-cell line killing by peritoneal exudate cells obtained from cyclophosphamide treated non-obese diabetic mice.
Endocrine journal 1995;42(2):259-63.
1995: T Marumo; Toshio Nakaki; K Hishikawa; H Suzuki; R Kato; Takao Saruta
Cyclosporin A inhibits nitric oxide synthase induction in vascular smooth muscle cells.
Hypertension 1995;25(4 Pt 2):764-8.
1995: K Hishikawa; Toshio Nakaki; T Marumo; H Suzuki; R Kato; Takao Saruta
Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells.
FEBS letters 1995;360(3):291-3.
1995: Takao Saruta
[Plasma renin activity (PRA)].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Su Pt 2():679-82.
1995: K Ito; H Maruyama; Hiroshi Hirose; K Kido; K Koyama; K Kataoka; Takao Saruta
Exogenous insulin dose-dependently suppresses glucopenia-induced glucagon secretion from perfused rat pancreas.
Metabolism: clinical and experimental 1995;44(3):358-62.
1995: K Hishikawa; Toshio Nakaki; T Marumo; H Suzuki; R Kato; Takao Saruta
Pressure enhances endothelin-1 release from cultured human endothelial cells.
Hypertension 1995;25(3):449-52.
1995: Takao Saruta; Y Kanno; Koichi Hayashi; H Suzuki
Renal effects of amlodipine.
Journal of human hypertension 1995;9 Suppl 1():S11-6.
1995: Hiroshi Hirose; H Maruyama; Y Seto; K Ito; T Fujita; K Dan; N Kanda; Takao Saruta; R Kato
Effects of D-phenylalanine-derivative hypoglycemic agent A-4166 on pancreatic alpha- and beta-cells: comparative study with glibenclamide.
Pharmacology 1995;50(3):175-81.
1995: Hirohiko Tsuganezawa; M Hayashi; Y Fujii; Y Yamaji; M Iyori; Takao Saruta
Corticosterone increases Na(+)-K(+)-ATPase activity in rat cortical collecting ducts with inhibition of 11 beta-hydroxysteroid dehydrogenase.
Renal physiology and biochemistry 1995;18(2):66-72.
1995: H Kawabe; Ikuo Saito; Takao Saruta
[Inhibitors of renin-angiotensin system].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Su Pt 1():994-7.
1995: H Suzuki; Hirotaka Shibata; T Maruyama; Yuzuru Ishimura; Takao Saruta
Significance of steroidogenic enzymes in the pathogenesis of hyperfunctioning and non-hyperfunctioning adrenal tumor.
Steroids 1995;60(1):42-7.
1995: Hiroo Kumagai; H Suzuki; M Ichikawa; M Nishizawa; M Ryuzaki; Koichiro Kumagai; Takao Saruta
Different responses of renal blood flow and sympathetic nerve activity to captopril and nicardipine in conscious renal hypertensive rabbits.
Journal of cardiovascular pharmacology 1995;25(1):57-64.
1994: Masahito Jimbo; H Suzuki; M Ichikawa; Koichiro Kumagai; M Nishizawa; Takao Saruta
Role of nitric oxide in regulation of baroreceptor reflex.
Journal of the autonomic nervous system 1994;50(2):209-19.
1994: M Ichikawa; H Suzuki; Koichiro Kumagai; M Ryuzaki; Hiroo Kumagai; Masahito Jimbo; M Nishizawa; Takao Saruta
Effects of antihypertensive agents on baroreceptor function in early hypertensive rats.
Hypertension 1994;24(6):808-15.
1994: H Okada; H Suzuki; Y Kanno; Y Yamamura; Takao Saruta
Chronic and selective vasopressin blockade in spontaneously hypertensive rats.
The American journal of physiology 1994;267(6 Pt 2):R1467-71.
1994: M Naitoh; H Suzuki; M Murakami; A Matsumoto; Kikuo Arakawa; Atsuhiro Ichihara; H Nakamoto; K Oka; Y Yamamura; Takao Saruta
Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious dogs.
The American journal of physiology 1994;267(6 Pt 2):H2245-54.
1994: Koichi Hayashi; R Loutzenhiser; Murray Epstein; H Suzuki; Takao Saruta
Multiple factors contribute to acetylcholine-induced renal afferent arteriolar vasodilation during myogenic and norepinephrine- and KCl-induced vasoconstriction. Studies in the isolated perfused hydronephrotic kidney.
Circulation research 1994;75(5):821-8.
1994: Hirotaka Shibata; H Suzuki; M Murakami; A Sato; Takao Saruta
Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile.
Journal of hypertension 1994;12(11):1275-84.
1994: C Igarashi; T Maruyama; Ikuko Ezawa; I Takei; Takao Saruta
WBN/Kob rat: a new model of spontaneous diabetes, osteopenia and systemic hemosiderin deposition.
Bone and mineral 1994;27(2):133-44.
1994: M Hayashi; S Sasaki; Hirohiko Tsuganezawa; Toshiaki Monkawa; W Kitajima; K Konishi; K Fushimi; F Marumo; Takao Saruta
Expression and distribution of aquaporin of collecting duct are regulated by vasopressin V2 receptor in rat kidney.
The Journal of clinical investigation 1994;94(5):1778-83.
1994: Hiroshi Hirose; H Maruyama; K Ito; K Kido; K Koyama; Takao Saruta
Effects of diazoxide on alpha- and beta-cell function in isolated perfused rat pancreas.
Diabetes research and clinical practice 1994;25(2):77-82.
1994: Koichiro Kumagai; H Suzuki; M Ichikawa; Masahito Jimbo; M Murakami; M Ryuzaki; Takao Saruta
Nitric oxide increases renal blood flow by interacting with the sympathetic nervous system.
Hypertension 1994;24(2):220-6.
1994: Takao Saruta
Recent research on hypertension.
Clinical science (London, England : 1979) 1994;87(2):117-8.
1994: H Okada; H Suzuki; H Uchida; Y Kanno; Y Kitamura; Tadakazu Hisamatsu; N Deguchi; D Hayashi; Takao Saruta
Acquired idiopathic pure red cell aplasia in a hemodialyzed patient with inactive systemic lupus erythematosus.
Internal medicine (Tokyo, Japan) 1994;33(8):492-5.
1994: H Kawabe; Ikuo Saito; C Hasegawa; S Nagano; Takao Saruta
Circulatory and plasma catecholamine responses to mental stress in young subjects with two different types of hypertension.
Angiology 1994;45(6):435-41.
1994: H Okada; K Konishi; H Suzuki; Takao Saruta; H Sakaguchi
Idiopathic progressive glomerulopathy with extensive subendothelial and mesangial immune deposit formation.
Clinical nephrology 1994;41(6):338-41.
1994: I Saito; Takao Saruta
Hypertension in thyroid disorders.
Endocrinology and metabolism clinics of North America 1994;23(2):379-86.
1994: Takao Saruta; M Ishii; K Abe; I Iimura
Efficacy and safety of amlodipine in hypertensive patients with renal dysfunction.
Clinical cardiology 1994;17(6):317-24.
1994: H Suzuki; Hirotaka Shibata; T Takita; Shu Wakino; T Ogishima; Yuzuru Ishimura; Takao Saruta
Steroid contents and cortical steroidogenic enzymes in non-hyperfunctioning adrenal adenoma.
Endocrine journal 1994;41(3):267-74.
1994: H Kawabe; Ikuo Saito; S Nagano; Takao Saruta
Relation of home blood pressure to body weight in young normotensive men with or without family history of hypertension.
American journal of hypertension 1994;7(6):498-502.
1994: K Hishikawa; Toshio Nakaki; T Marumo; M Hayashi; H Suzuki; R Kato; Takao Saruta
Pressure promotes DNA synthesis in rat cultured vascular smooth muscle cells.
The Journal of clinical investigation 1994;93(5):1975-80.
1994: A Sato; H Suzuki; Y Nakazato; Hirotaka Shibata; T Inagami; Takao Saruta
Increased expression of vascular angiotensin II type 1A receptor gene in glucocorticoid-induced hypertension.
Journal of hypertension 1994;12(5):511-6.
1994: Hiroshi Hirose; H Maruyama; K Ito; Y Seto; K Kido; K Koyama; K Dan; Takao Saruta; R Kato
Effects of N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine (A-4166) on insulin and glucagon secretion in isolated perfused rat pancreas.
Pharmacology 1994;48(4):205-10.
1994: H Okada; H Suzuki; Y Kanno; Y Yamamura; Takao Saruta
Effects of vasopressin V1 and V2 receptor antagonists on progressive renal failure in rats.
Clinical science (London, England : 1979) 1994;86(4):399-404.
1994: Hiroshi Hirose; H Maruyama; K Kido; K Ito; K Koyama; Y Tashiro; Takao Saruta
Alpha- and beta-cell function in obese Zucker (fa/fa) rats: a study with the isolated perfused pancreas.
Clinical science (London, England : 1979) 1994;86(3):311-6.
1994: Y Kanno; H Suzuki; H Okada; Takao Saruta
Renal protective effects of amlodipine on partially nephrectomized spontaneously hypertensive rats fed a high-salt diet.
Journal of cardiovascular pharmacology 1994;23(3):480-4.
1994: H Okada; K Konishi; Y Nakazato; Y Kanno; H Suzuki; H Sakaguchi; Takao Saruta
Interleukin-4 expression in mesangial proliferative glomerulonephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1994;23(2):242-6.
1994: M Nakamura; H Suzuki; H Yamakawa; Y Ohno; Takao Saruta
Calcium restriction accelerates salt-induced hypertension in young spontaneously hypertensive rats.
The American journal of the medical sciences 1994;307 Suppl 1():S138-41.
1994: A Sato; H Suzuki; M Murakami; Y Nakazato; Y Iwaita; Takao Saruta
Glucocorticoid increases angiotensin II type 1 receptor and its gene expression.
Hypertension 1994;23(1):25-30.
1994: T Takenaka; H Suzuki; H Ikenaga; Y Itaya; H Yamakawa; Y Sakamaki; Takao Saruta
Effects of a calcium channel blocker, nicardipine, on pressure-natriuresis in Dahl salt-sensitive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1994;16(1):77-88.
1994: Ikuo Saito; S Itsuji; E Takeshita; H Kawabe; M Nishino; H Wainai; C Hasegawa; Takao Saruta; S Nagano; T Sekihara
Increased urinary dopamine excretion in young patients with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1994;16(1):29-39.
1994: Y Kanno; H Okada; H Suzuki; H Ikenaga; Takao Saruta
Nonpeptide angiotensin II type 1 receptor antagonist prevents nephrosclerosis in hypertensive rats.
Blood pressure. Supplement 1994;5():67-70.
1994: Alberto Falorni; C E Grubin; Izumi Takei; Akira Shimada; Akira Kasuga; T Maruyama; Y Ozawa; T Kasatani; Takao Saruta; L Li
Radioimmunoassay detects the frequent occurrence of autoantibodies to the Mr 65,000 isoform of glutamic acid decarboxylase in Japanese insulin-dependent diabetes.
Autoimmunity 1994;19(2):113-25.
1994: Takao Saruta
[Recent advances in antihypertensive therapy--JNC-V].
Japanese circulation journal 1994;58 Suppl 4():1375-80.
1993: Y Nakazato; H Okada; A Sato; Y Iwaita; T Hayashida; M Hayashi; H Suzuki; Takao Saruta
Interleukin 4 downregulates cell growth and prostaglandin release of human mesangial cells.
Biochemical and biophysical research communications 1993;197(2):486-93.
1993: Akira Kasuga; T Maruyama; Izumi Takei; Akira Shimada; T Kasatani; K Watanabe; Takao Saruta; Toshio Nakaki; S Habu; J Miyazaki
The role of cytotoxic macrophages in non-obese diabetic mice: cytotoxicity against murine mastocytoma and beta-cell lines.
Diabetologia 1993;36(12):1252-7.
1993: Koichi Hayashi; H Suzuki; Takao Saruta
Segmental differences in angiotensin receptor subtypes in interlobular artery of hydronephrotic rat kidneys.
The American journal of physiology 1993;265(6 Pt 2):F881-5.
1993: M Hayashi; M Iyori; Y Yamaji; Takao Saruta
Effects of in vivo and in vitro alkali treatment on intracellular pH regulation of OMCDis cells.
The American journal of physiology 1993;265(5 Pt 2):F729-35.
1993: T Marumo; Toshio Nakaki; H Adachi; H Esumi; H Suzuki; Takao Saruta; R Kato
Nitric oxide synthase mRNA in endothelial cells: synergistic induction by interferon-gamma, tumor necrosis factor-alpha and lipopolysaccharide and inhibition by dexamethasone.
Japanese journal of pharmacology 1993;63(3):327-34.
1993: M Naitoh; H Suzuki; M Murakami; A Matsumoto; Atsuhiro Ichihara; H Nakamoto; Y Yamamura; Takao Saruta
Arginine vasopressin produces renal vasodilation via V2 receptors in conscious dogs.
The American journal of physiology 1993;265(4 Pt 2):R934-42.
1993: Atsuhiro Ichihara; H Suzuki; Takao Saruta
Effects of magnesium on the renin-angiotensin-aldosterone system in human subjects.
The Journal of laboratory and clinical medicine 1993;122(4):432-40.
1993: Hiroshi Hirose; H Maruyama; K Ito; K Kido; K Koyama; Takao Saruta
Effects of alpha 2- and beta-adrenergic agonism on glucagon secretion from perfused pancreata of normal and streptozocin-induced diabetic rats.
Metabolism: clinical and experimental 1993;42(8):1072-6.
1993: Izumi Takei; T Kasatani; K Watanabe; Akira Kasuga; Akira Shimada; T Maruyama; Takao Saruta; H Nomaguchi
Detection of heat shock protein in patients with insulin-dependent diabetes mellitus.
Diabetes research and clinical practice 1993;21(1):25-9.
1993: Hiroo Kumagai; H Suzuki; M Ichikawa; Y Matsumura; Masahito Jimbo; M Ryuzaki; Takao Saruta
Central and peripheral vasopressin interact differently with sympathetic nervous system and renin-angiotensin system in renal hypertensive rabbits.
Circulation research 1993;72(6):1255-65.
1993: K Hishikawa; Toshio Nakaki; H Suzuki; R Kato; Takao Saruta
Role of L-arginine-nitric oxide pathway in hypertension.
Journal of hypertension 1993;11(6):639-45.
1993: H Okada; H Suzuki; H Sakaguchi; Takao Saruta
Dissociation of clinical manifestation and histopathology in the course of mesangial injury by anti-thymocyte antibody.
Pathology, research and practice 1993;189(4):437-42.
1993: K Watanabe; T Kameya; A Yamauchi; N Yamamoto; A Kuwayama; I Takei; H Maruyama; Takao Saruta
Thyrotropin-producing microadenoma associated with pituitary resistance to thyroid hormone.
The Journal of clinical endocrinology and metabolism 1993;76(4):1025-30.
1993: Yoichi Ohno; H Suzuki; H Yamakawa; M Nakamura; K Otsuka; Takao Saruta
Impaired insulin sensitivity in young, lean normotensive offspring of essential hypertensives: possible role of disturbed calcium metabolism.
Journal of hypertension 1993;11(4):421-6.
1993: H Ikenaga; H Suzuki; N Ishii; H Itoh; Takao Saruta
Enzymuria in non-insulin-dependent diabetic patients: signs of tubular cell dysfunction.
Clinical science (London, England : 1979) 1993;84(4):469-75.
1993: H Kawabe; O U Lopes; C L Chernicky; K Bridget Brosnihan; Takao Saruta; Carlos M Ferrario
Effects of large and small transections of the preoptic-hypothalamic region on hydromineral regulation in rats.
Endocrine journal 1993;40(2):249-56.
1993: Hirotaka Shibata; H Suzuki; T Ogishima; Yuzuru Ishimura; Takao Saruta
Significance of steroidogenic enzymes in the pathogenesis of adrenal tumour.
Acta endocrinologica 1993;128(3):235-42.
1993: Takao Saruta; H Suzuki
Efficacy of manidipine in the treatment of hypertension with renal impairment: a multicenter trial.
American heart journal 1993;125(2 Pt 2):630-4.
1993: Akira Kasuga; Izumi Takei; S Tasaka; H Shibata; H Maruyama; Takao Saruta; K Kataoka
A case of aldosterone producing adenoma associated with high PRA after long-term angiotensin converting enzyme inhibitor treatment.
Endocrine journal 1993;40(1):47-52.
1993: Hiroshi Hirose; H Maruyama; K Ito; K Koyama; K Kido; Takao Saruta
Glucose-induced insulin secretion and alpha 2-adrenergic receptor subtypes.
The Journal of laboratory and clinical medicine 1993;121(1):32-7.
1993: Ikuo Saito; H Kawabe; Takao Saruta
[Deoxycorticosterone-producing adrenal tumor].
Ryōikibetsu shōkōgun shirīzu 1993;(1):495-7.
1993: H Kawabe; Takao Saruta
[Corticosterone producing tumor].
Ryōikibetsu shōkōgun shirīzu 1993;(1):456-9.
1993: Takao Saruta
[Aldosterone producing adenoma].
Ryōikibetsu shōkōgun shirīzu 1993;(1):404-7.
1993: H Ikenaga; H Suzuki; N Ishii; H Itoh; Takao Saruta
Role of NO on pressure-natriuresis in Wistar-Kyoto and spontaneously hypertensive rats.
Kidney international 1993;43(1):205-11.
1992: Izumi Takei; Y Asaba; T Kasatani; T Maruyama; K Watanabe; T Yanagawa; Takao Saruta; T Ishii
Suppression of development of diabetes in NOD mice by lactate dehydrogenase virus infection.
Journal of autoimmunity 1992;5(6):665-73.
1992: Hiroo Kumagai; H Suzuki; Y Matsumura; M Ryuzaki; Takao Saruta
Differential effects of captopril and nicardipine on baroreflex control of sympathetic nerve activity and heart rate in renal hypertension.
Journal of hypertension 1992;10(12):1485-91.
1992: Ikuo Saito; M Nishino; H Kawabe; H Wainai; C Hasegawa; Takao Saruta; S Nagano; T Sekihara
Leisure time physical activity and insulin resistance in young obese students with hypertension.
American journal of hypertension 1992;5(12 Pt 1):915-8.
1992: Koichiro Kumagai; H Suzuki; M Ryuzaki; Hiroo Kumagai; M Ichikawa; Masahito Jimbo; Y Matsumura; Takao Saruta
Effects of antihypertensive agents on arterial baroreceptor reflexes in conscious rats.
Hypertension 1992;20(5):701-9.
1992: Hiroshi Hirose; H Maruyama; K Itoh; K Koyama; K Kido; Takao Saruta
Alpha-2 adrenergic agonism stimulates islet glucagon release from perfused rat pancreas: possible involvement of alpha-2A adrenergic receptor subtype.
Acta endocrinologica 1992;127(3):279-83.
1992: A Sato; H Suzuki; Y Iwaita; Y Nakazato; H Kato; Takao Saruta
Dexamethasone potentiates production of inositol trisphosphate evoked by endothelin-1 in vascular smooth muscle cells.
Journal of cardiovascular pharmacology 1992;20(2):290-5.
1992: H Yamakawa; H Suzuki; M Nakamura; Y Ohno; Takao Saruta
Disturbed calcium metabolism in offspring of hypertensive parents.
Hypertension 1992;19(6 Pt 1):528-34.
1992: K Koyama; Hiroshi Hirose; H Maruyama; K Itoh; K Kido; Takao Saruta
Arachidonic acid metabolites and alpha 2-adrenoceptor-mediated glucagon secretion in rats.
Diabetes research and clinical practice 1992;16(3):229-32.
1992: H Suzuki; H Ikenaga; K Hishikawa; Toshio Nakaki; R Kato; Takao Saruta
Increases in NO2-/NO3- excretion in the urine as an indicator of the release of endothelium-derived relaxing factor during elevation of blood pressure.
Clinical science (London, England : 1979) 1992;82(6):631-4.
1992: H Nakamoto; H Suzuki; Y Kageyama; M Murakami; A Ohishi; M Naitoh; Atsuhiro Ichihara; Takao Saruta
Depressor systems contribute to hypertension induced by glucocorticoid excess in dogs.
Journal of hypertension 1992;10(6):561-9.
1992: K Hishikawa; Toshio Nakaki; H Suzuki; Takao Saruta; R Kato
Transmural pressure inhibits nitric oxide release from human endothelial cells.
European journal of pharmacology 1992;215(2-3):329-31.
1992: H Okada; H Suzuki; K Konishi; H Sakaguchi; Takao Saruta
Histological alterations in renal specimens as indicators of prognosis of IgA nephropathy.
Clinical nephrology 1992;37(5):235-8.
1992: M Ryuzaki; H Suzuki; Koichiro Kumagai; Hiroo Kumagai; M Ichikawa; S Matsukawa; Y Matsumura; Takao Saruta
Renal nerves contribute to salt-induced hypertension in sinoaortic-denervated uninephrectomized rabbits.
The American journal of physiology 1992;262(5 Pt 2):R733-7.
1992: H Suzuki; Hirotaka Shibata; M Murakami; H Nakamoto; K Kondo; Takao Saruta
Case report: hypertension in Cushing's syndrome.
The American journal of the medical sciences 1992;303(5):329-32.
1992: H Kawabe; Ikuo Saito; Takao Saruta
[Disease models of steroid-induced hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():757-62.
1992: Takao Saruta
[Secondary hypertension due to renin-producing tumor].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():703-6.
1992: Takao Saruta
[Treatment of hypertension in diabetic patients].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():225-31.
1992: Ikuo Saito; H Kawabe; Takao Saruta
[Adrenal corticosteroid and disease models of hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():746-9.
1992: Y Yamaji; M Hayashi; M Iyori; W Kitajima; Takao Saruta
Chronic DOC treatment enhances Na(+)-H+ exchanger activity of beta-intercalated cells in rabbit CCD.
The American journal of physiology 1992;262(5 Pt 2):F712-7.
1992: Takao Saruta
[Etiological significance of the renin-angiotensin system in essential hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():296-302.
1992: A Sato; H Suzuki; Y Iwaita; Y Nakazato; H Kato; Takao Saruta
Potentiation of inositol trisphosphate production by dexamethasone.
Hypertension 1992;19(1):109-15.
1992: H Kawabe; T Furukawa; Ikuo Saito; Takao Saruta
Importance of atrial natriuretic hormone in an exaggerated natriuresis during acute sodium load in primary aldosteronism.
Acta endocrinologica 1992;126(1):37-43.
1992: M Nakamura; H Suzuki; H Yamakawa; Takao Saruta
Role of platelet cytosolic calcium in regulation of blood pressure in patients on chronic hemodialysis.
Nephron 1992;61(4):435-41.
1992: Takao Saruta
[Dialysis-associated hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():663-8.
1992: H Ikenaga; H Suzuki; Takao Saruta
Effects of manidipine on blood pressure and renal function in salt-loaded, spontaneously hypertensive rats.
Blood pressure. Supplement 1992;3():75-9.
1992: H Suzuki; H Ikenaga; Takao Saruta
[Dialysis-associated hypotension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():669-75.
1992: K Hishikawa; Toshio Nakaki; M Tsuda; H Esumi; H Ohshima; H Suzuki; Takao Saruta; R Kato
Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man.
Japanese heart journal 1992;33(1):41-8.
1992: K Hishikawa; Toshio Nakaki; H Suzuki; Takao Saruta; R Kato
New method of investigating functional roles of pressure-sensitive mechanoreceptor in human endothelial cells.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S66-7.
1992: K Hishikawa; Toshio Nakaki; H Suzuki; R Kato; Takao Saruta
L-arginine as an antihypertensive agent.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S196-7.
1991: T Tominaga; H Suzuki; Y Ogata; S Matsukawa; Takao Saruta
The role of sex hormones and sodium intake in postmenopausal hypertension.
Journal of human hypertension 1991;5(6):495-500.
1991: M Murakami; H Suzuki; Atsuhiro Ichihara; M Naitoh; H Nakamoto; Takao Saruta
Effects of L-arginine on systemic and renal haemodynamics in conscious dogs.
Clinical science (London, England : 1979) 1991;81(6):727-32.
1991: H Yamakawa; H Suzuki; M Nakamura; Yoichi Ohno; Takao Saruta
Role of platelet cytosolic calcium in the response to salt intake in normotensive subjects.
Clinical and experimental pharmacology & physiology 1991;18(9):627-9.
1991: Ikuo Saito; H Kawabe; C Hasegawa; Y Iwaida; H Yamakawa; Takao Saruta; E Takeshita; S Nagano; T Sekihara
Effect of L-dopa in young patients with hypertension.
Angiology 1991;42(9):691-5.
1991: T Ogishima; Hirotaka Shibata; H Shimada; Fumiko Mitani; H Suzuki; Takao Saruta; Yuzuru Ishimura
Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism.
The Journal of biological chemistry 1991;266(17):10731-4.
1991: M Ryuzaki; H Suzuki; Koichiro Kumagai; Hiroo Kumagai; M Ichikawa; Y Matsumura; Takao Saruta
Role of vasopressin in salt-induced hypertension in baroreceptor-denervated uninephrectomized rabbits.
Hypertension 1991;17(6 Pt 2):1085-91.
1991: T Takenaka; H Suzuki; Y Sakamaki; Y Itaya; Takao Saruta
Contribution of prostaglandins to pressure natriuresis in Dahl salt-sensitive rats.
American journal of hypertension 1991;4(6):489-93.
1991: M Hayashi; Y Yamaji; W Kitajima; Takao Saruta
Effects of high salt intake on dopamine production in rat kidney.
The American journal of physiology 1991;260(5 Pt 1):E675-9.
1991: Hirotaka Shibata; T Ogishima; Fumiko Mitani; H Suzuki; M Murakami; Takao Saruta; Yuzuru Ishimura
Regulation of aldosterone synthase cytochrome P-450 in rat adrenals by angiotensin II and potassium.
Endocrinology 1991;128(5):2534-9.
1991: K Konishi; M Nakamura; H Yamakawa; H Suzuki; Takao Saruta; H Hanaoka; Fereydoun Davatchi
Hypophosphatemic osteomalacia in von Recklinghausen neurofibromatosis.
The American journal of the medical sciences 1991;301(5):322-8.
1991: M Hayashi; Y Yamaji; M Iyori; W Kitajima; Takao Saruta
Effect of isoproterenol on intracellular pH of the intercalated cells in the rabbit cortical collecting ducts.
The Journal of clinical investigation 1991;87(4):1153-7.
1991: T Maruyama; K Watanabe; T Yanagawa; T Kasatani; Akira Kasuga; Akira Shimada; Izumi Takei; Y Suzuki; K Kataoka; Takao Saruta
The suppressive effect of anti-asialo GM1 antibody on low-dose streptozotocin-induced diabetes in CD-1 mice.
Diabetes research (Edinburgh, Scotland) 1991;16(4):171-5.
1991: H Wainai; Fuminori Katsukawa; Izumi Takei; H Maruyama; K Kataoka; Takao Saruta
Influence of glycemic control and hypertension on urinary microprotein excretion in non-insulin-dependent diabetes mellitus.
The Journal of diabetic complications 1991;5(2-3):160-1.
1991: H Maruyama; Takao Saruta; H Itoh; K Koyama; K Kido; K Itoh; I Takei; K Kataoka
Effect of alpha-adrenergic blockade on blood pressure, glucose, and lipid metabolism in hypertensive patients with non-insulin-dependent diabetes mellitus.
American heart journal 1991;121(4 Pt 2):1302-6.
1991: H Nakamoto; H Suzuki; M Murakami; Y Kageyama; M Naitoh; Y Sakamaki; A Ohishi; Takao Saruta
Different effects of low and high doses of endothelin on haemodynamics and hormones in the normotensive conscious dog.
Journal of hypertension 1991;9(4):337-44.
1991: M Murakami; H Suzuki; H Nakamoto; Y Kageyama; M Naitoh; Y Sakamaki; Takao Saruta
Calcitonin gene-related peptide modulates adrenal hormones in conscious dogs.
Acta endocrinologica 1991;124(3):346-52.
1991: H Kawabe; T Furukawa; T Takenaka; Ikuo Saito; Takao Saruta
Importance of the renin-angiotensin system in sodium regulation in essential hypertension.
American journal of hypertension 1991;4(2 Pt 1):119-25.
1991: Takao Saruta; K Nishikawa
Characteristics of a new angiotensin converting enzyme inhibitor: delapril.
American journal of hypertension 1991;4(1 Pt 2):23S-28S.
1991: H Nakamoto; H Suzuki; Y Kageyama; A Ohishi; M Murakami; M Naitoh; Takao Saruta
Characterization of alterations of hemodynamics and neuroendocrine hormones in dexamethasone induced hypertension in dogs.
Clinical and experimental hypertension. Part A, Theory and practice 1991;13(4):587-606.
1991: H Kato; H Suzuki; S Tajima; Y Ogata; T Tominaga; A Sato; Takao Saruta
Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells.
Journal of hypertension 1991;9(1):17-22.
1991: H Inamoto; R Ozaki; T Matsuzaki; M Wakui; Takao Saruta; A Osawa
Incidence and mortality patterns of malignancy and factors affecting the risk of malignancy in dialysis patients.
Nephron 1991;59(4):611-7.
1990: Hiroo Kumagai; H Suzuki; M Ryuzaki; S Matsukawa; Takao Saruta
Baroreflex control of renal sympathetic nerve activity is potentiated at early phase of two-kidney, one-clip Goldblatt hypertension in conscious rabbits.
Circulation research 1990;67(6):1309-22.
1990: Hiroyuki Sasamura; H Suzuki; T Takita; M Hayashi; J Ohno; T Shirai; Takao Saruta
Response of plasma immunoreactive active renin, inactive renin, plasma renin activity, and aldosterone to hemodialysis in patients with diabetic nephropathy.
Clinical nephrology 1990;33(6):288-92.
1990: Ikuo Saito; E Takeshita; S Hayashi; T Takenaka; M Murakami; Takao Saruta; S Nagano; T Sekihara
Effect of captopril on plasma prolactin in patients with essential hypertension.
Angiology 1990;41(5):377-81.
1990: H Okada; H Suzuki; M Murakami; Y Ogata; T Takenaka; H Sakaguchi; Y Hosoda; Takao Saruta
Takayasu's arteritis with heart failure due to atherosclerosis.
Japanese journal of medicine 1990;29(3):309-12.
1990: H Katsumata; H Suzuki; A Ohishi; H Nakamoto; Takao Saruta; H Sakaguchi
Effects of antihypertensive agents on blood pressure and the progress of renal failure in partially nephrectomized spontaneously hypertensive rats.
Laboratory investigation; a journal of technical methods and pathology 1990;62(4):474-80.
1990: Ikuo Saito; E Takeshita; S Hayashi; T Takenaka; M Murakami; Takao Saruta; S Nagano; T Sekihara
Comparison of clinic and home blood pressure levels and the role of the sympathetic nervous system in clinic-home differences.
American journal of hypertension 1990;3(3):219-24.
1990: H Kawabe; H Suzuki; Y Itaya; Takao Saruta
Pressor and hormonal responses to intravenous injection of metoclopramide in normotensive and hypertensive patients.
Japanese journal of medicine 1990;29(2):174-9.
1990: Hiroyuki Sasamura; H Suzuki; R Kato; Takao Saruta
Effects of angiotensin II, ACTH, and KCl on the adrenal renin-angiotensin system in the rat.
Acta endocrinologica 1990;122(3):369-73.
1990: Ikuo Saito; Takao Saruta
[Therapeutic drug monitoring of inhibitors of renin-angiotensin system].
Nihon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():1146-8.
1990: T Imafuku; Z Ogawa; H Itoh; H Suzuki; Takao Saruta
Na+, K(+)-ATPase inhibitory activity of fractionated urine during changes in dietary sodium intake in man.
Endocrinologia japonica 1990;37(1):39-46.
1990: Takao Saruta
[Plasma renin activity assay and the clinical significance].
Nihon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():201-4.
1990: Hiroyuki Sasamura; K Nagata; Y Yamazoe; M Shimada; Takao Saruta; R Kato
Effect of growth hormone on rat hepatic cytochrome P-450f mRNA: a new mode of regulation.
Molecular and cellular endocrinology 1990;68(1):53-60.
1990: M Hayashi; Y Yamaji; W Kitajima; Takao Saruta
Aromatic L-amino acid decarboxylase activity along the rat nephron.
The American journal of physiology 1990;258(1 Pt 2):F28-33.
1990: T Takenaka; H Suzuki; T Furukawa; Y Ogata; Takao Saruta
Role of intrarenal renin-angiotensin system on pressure-natriuresis in spontaneously hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1990;12(8):1377-94.
1989: K Hayashi; H Suzuki; H Katsumata; A Ohishi; H Nakamoto; Takao Saruta
The influence of dietary protein on the synthesis of vasoactive substances in subtotally nephrectomized spontaneously hypertensive rats.
Japanese heart journal 1989;30(6):917-27.
1989: H Nakamoto; H Suzuki; M Murakami; Y Kageyama; A Ohishi; K Fukuda; Shingo Hori; Takao Saruta
Effects of endothelin on systemic and renal haemodynamics and neuroendocrine hormones in conscious dogs.
Clinical science (London, England : 1979) 1989;77(5):567-72.
1989: Y Nakazato; H Suzuki; Takao Saruta
Characterization of subclones of Madin-Darby canine kidney renal epithelial cell line.
Biochimica et biophysica acta 1989;1014(1):57-65.
1989: M Murakami; H Suzuki; S Nakajima; H Nakamoto; Y Kageyama; Takao Saruta
Calcitonin gene-related peptide is an inhibitor of aldosterone secretion.
Endocrinology 1989;125(4):2227-9.
1989: T Yanagawa; T Maruyama; Izumi Takei; Y Asaba; T Takahashi; T Ishii; K Kataoka; Takao Saruta; S Minoshima; Nobuyoshi Shimizu
The suppressive effect of cyclophosphamide on low-dose streptozotocin-induced diabetes in mice.
Diabetes research (Edinburgh, Scotland) 1989;12(2):79-83.
1989: M Ryuzaki; K Konishi; Akira Kasuga; Hiroo Kumagai; H Suzuki; S Abe; Takao Saruta; H Takami; M Tashiro
Spontaneous rupture of the quadriceps tendon in patients on maintenance hemodialysis--report of three cases with clinicopathological observations.
Clinical nephrology 1989;32(3):144-8.
1989: K Hosokawa; M Taniyama; T Okabe; H Maruyama; K Kataoka; Takao Saruta
Effects of streptozotocin-induced diabetes on glucose utilization that was stimulated by various agents in rat thymocytes.
Diabetes research (Edinburgh, Scotland) 1989;12(1):43-6.
1989: Hiroo Kumagai; H Suzuki; S Matsukawa; M Ryuzaki; Takao Saruta
Captopril therapy following percutaneous transluminal angioplasty for bilateral renal artery stenosis.
Archives of internal medicine 1989;149(9):1973-6.
1989: M Hata; M Tachibana; S Baba; Nobuhiro Deguchi; H Tazaki; H Suzuki; Takao Saruta
[Therapeutic guide for renovascular hypertension with reevaluation of surgical treatment].
Hinyokika kiyo. Acta urologica Japonica 1989;35(6):1035-40.
1989: T Maruyama; Izumi Takei; Y Asaba; T Yanagawa; T Takahashi; H Itoh; Y Suzuki; K Kataoka; Takao Saruta; T Ishii
Insulin autoantibodies in mouse models of insulin-dependent diabetes.
Diabetes research (Edinburgh, Scotland) 1989;11(2):61-5.
1989: A Ohishi; H Suzuki; H Nakamoto; H Katsumata; H Sakaguchi; Takao Saruta
Differences in the effects of angiotensin converting enzyme inhibitors with or without a thiol group in chronic renal failure in rats.
Clinical science (London, England : 1979) 1989;76(4):353-6.
1989: Ikuo Saito; S Itsuji; E Takeshita; T Takenaka; T Furukawa; Takao Saruta; S Nagano; T Sekihara
Increased sympathetic nerve activity at home in young subjects with hypertension.
Clinical and experimental hypertension. Part A, Theory and practice 1989;11 Suppl 1():389-95.
1989: Takao Saruta
Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction.
American heart journal 1989;117(1):243-9.
1989: T Yasui; Takao Saruta
Radioimmunoassay of kinins and its application to purification of kininogens.
Advances in experimental medicine and biology 1989;247B():325-30.
1989: Takao Saruta
Therapeutic regime of enalapril maleate in Japan.
Advances in experimental medicine and biology 1989;247A():55-61.
1988: H Suzuki; T Tominaga; Hiroo Kumagai; Takao Saruta
Effects of first-line antihypertensive agents on sexual function and sex hormones.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S649-51.
1988: S Nakajima; H Suzuki; Y Kageyama; T Takita; Takao Saruta
Hormonal responses to synthetic atrial natriuretic peptide in patients on regular hemodialysis.
Acta endocrinologica 1988;119(2):257-62.
1988: Y Fuji; H Suzuki; H Katsumata; S Nakajima; Takao Saruta
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
Journal of cardiovascular pharmacology 1988;11(4):438-43.
1987: Ikuo Saito; E Takeshita; Takao Saruta; S Nagano; T Sekihara
Blood pressure response to a calcium entry blocker in normotensive subjects with or without a family history of hypertension.
Angiology 1987;38(12):883-8.
1987: S Matsukawa; H Suzuki; Y Itaya; S Nakajima; Takao Saruta
Short- and long-term efficacy of nifedipine in hypertensive patients with impaired renal function, with special reference to influencing factors.
Journal of clinical hypertension 1987;3(4):452-62.
1987: S Narumi; Y Fuji; M Yoshizawa; T Yasui; Takao Saruta
Effect of vasoactive substances on natriuresis induced by atrial natriuretic peptide in isolated perfused rat kidneys.
Endocrinologia japonica 1987;34(6):879-85.
1987: S Matsukawa; H Suzuki; Y Itaya; Hiroo Kumagai; Takao Saruta
The renal antihypertensive effect of angiotensin I converting enzyme inhibitors.
Journal of hypertension 1987;5(6):705-10.
1987: Y Kageyama; H Suzuki; K Arima; K Kondo; Takao Saruta
Effects of calcium loading in DOCA-salt hypertensive rats.
Japanese circulation journal 1987;51(11):1315-24.
1987: Takao Saruta; H Suzuki; T Takita; Ikuo Saito; M Murai; H Tazaki
Pre-operative evaluation of the prognosis of hypertension in primary aldosteronism owing to adenoma.
Acta endocrinologica 1987;116(2):229-34.
1987: Y Kageyama; H Suzuki; K Arima; Takao Saruta
Oral calcium treatment lowers blood pressure in renovascular hypertensive rats by suppressing the renin-angiotensin system.
Hypertension 1987;10(4):375-82.
1986: I Saito; E Takeshita; Takao Saruta; S Nagano; T Sekihara
Effect of a calcium entry blocker on blood pressure, plasma renin activity, aldosterone and catecholamines in normotensive subjects.
Clinical endocrinology 1986;24(5):565-70.
1986: I Saito; E Takeshita; Takao Saruta; S Nagano; T Sekihara
Urinary dopamine excretion in normotensive subjects with or without family history of hypertension.
Journal of hypertension 1986;4(1):57-60.
1985: H Kawabe; Y Itaya; H Suzuki; K Kondo; Takao Saruta
Metoclopramide in the diagnosis of pheochromocytoma.
Japanese heart journal 1985;26(4):557-66.
1984: I Saito; E Takeshita; Takao Saruta; S Nagano; T Sekihara
Plasma prolactin, renin and catecholamines in young normotensive and borderline hypertensive subjects.
Journal of hypertension 1984;2(1):61-4.