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Kazuki Sasaki

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Y Makanae; K Nakazato; Kazuki Sasaki; S Kawada; N Ishii
Vitamin C administration attenuates overload-induced skeletal muscle hypertrophy in rats.
Abu Saleh Md Moin; Ji-Wom Kim; Takashi Matsuo; Naoto Minamino; Farhana Naznin; Marie Rhee; Kazuki Sasaki; Koji Toshinai; T M Zaved Waise; Hideki Yamaguchi; Kun-Ho Yoon; Masamitsu Nakazato
Neuroendocrine regulatory peptide-2 stimulates glucose-induced insulin secretion in vivo and in vitro.
Koji Toshinai; Hideki Yamaguchi; Haruaki Kageyama; Takashi Matsuo; Keiichi Koshinaka; Kazuki Sasaki; Seiji Shioda; Naoto Minamino; Masamitsu Nakazato
Neuroendocrine regulatory peptide-2 regulates feeding behavior via the orexin system in the hypothalamus.

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All Publications

2013: Y Makanae; K Nakazato; Kazuki Sasaki; S Kawada; N Ishii
Vitamin C administration attenuates overload-induced skeletal muscle hypertrophy in rats.
Acta physiologica (Oxford, England) 2013;208(1):57-65.
2012: Abu Saleh Md Moin; Ji-Wom Kim; Takashi Matsuo; Naoto Minamino; Farhana Naznin; Marie Rhee; Kazuki Sasaki; Koji Toshinai; T M Zaved Waise; Hideki Yamaguchi; Kun-Ho Yoon; Masamitsu Nakazato
Neuroendocrine regulatory peptide-2 stimulates glucose-induced insulin secretion in vivo and in vitro.
Biochemical and biophysical research communications 2012;428(4):512-7.
2010: Koji Toshinai; Hideki Yamaguchi; Haruaki Kageyama; Takashi Matsuo; Keiichi Koshinaka; Kazuki Sasaki; Seiji Shioda; Naoto Minamino; Masamitsu Nakazato
Neuroendocrine regulatory peptide-2 regulates feeding behavior via the orexin system in the hypothalamus.
American journal of physiology. Endocrinology and metabolism 2010;299(3):E394-401.
2010: Takashi Matsuo; Hideki Yamaguchi; Haruaki Kageyama; Kazuki Sasaki; Seiji Shioda; Naoto Minamino; Masamitsu Nakazato
Localization of neuroendocrine regulatory peptide-1 and-2 in human tissues.
Regulatory peptides 2010;163(1-3):43-8.
2009: Kazuki Sasaki; Yoshinori Satomi; Toshifumi Takao; Naoto Minamino
Snapshot peptidomics of the regulated secretory pathway.
Molecular & cellular proteomics : MCP 2009;8(7):1638-47.
2009: Masamitsu Tanaka; Kazuki Sasaki; Reiko Kamata; Yukari Hoshino; Kazuyoshi Yanagihara; Ryuichi Sakai
A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.
Molecular and cellular biology 2009;29(2):402-13.
2007: Tetsuo Ito; Noboru Maki; Osamu Hazeki; Kazuki Sasaki; Munenori Nekooki
Extracellular and transmembrane region of a podocalyxin-like protein 1 fragment identified from colon cancer cell lines.
Cell biology international 2007;31(12):1518-24.
2007: Hideki Yamaguchi; Kazuki Sasaki; Yoshinori Satomi; Takuya Shimbara; Haruaki Kageyama; Muhtashan S Mondal; Koji Toshinai; Yukari Date; Luis Javier González; Seiji Shioda; Toshifumi Takao; Masamitsu Nakazato; Naoto Minamino
Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -2.
The Journal of biological chemistry 2007;282(36):26354-60.
2007: Taro Hitosugi; Moritoshi Sato; Kazuki Sasaki; Yoshio Umezawa
Lipid raft specific knockdown of SRC family kinase activity inhibits cell adhesion and cell cycle progression of breast cancer cells.
Cancer research 2007;67(17):8139-48.
2007: Masamitsu Tanaka; Kazuki Sasaki; Reiko Kamata; Ryuichi Sakai
The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells.
Journal of cell science 2007;120(Pt 13):2179-89.
2007: Tadaomi Naka; Etsuko Katsumata; Kazuki Sasaki; Naoto Minamino; Motoi Yoshioka; Yoshio Takei
Natriuretic peptides in cetaceans: identification, molecular characterization and changes in plasma concentration after landing.
Zoological science 2007;24(6):577-87.
2007: Taro Hitosugi; Kazuki Sasaki; Moritoshi Sato; Yoshiko Suzuki; Yoshio Umezawa
Epidermal growth factor directs sex-specific steroid signaling through Src activation.
The Journal of biological chemistry 2007;282(14):10697-706.
2006: Sayaka Nagata; Johji Kato; Kazuki Sasaki; Naoto Minamino; Tanenao Eto; Kazuo Kitamura
Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system.
Biochemical and biophysical research communications 2006;350(4):1026-31.
2006: Nobuhisa Fukuda; Kazuki Sasaki; T V R S Sastry; Motomu Kanai; Masakatsu Shibasaki
Catalytic asymmetric total synthesis of (+)-lactacystin.
The Journal of organic chemistry 2006;71(3):1220-5.
2005: Tsuyoshi Mita; Kazuki Sasaki; Motomu Kanai; Masakatsu Shibasaki
Catalytic enantioselective conjugate addition of cyanide to alpha,beta-unsaturated N-acylpyrroles.
Journal of the American Chemical Society 2005;127(2):514-5.
2004: Muhammad Awais; Moritoshi Sato; Kazuki Sasaki; Yoshio Umezawa
A genetically encoded fluorescent indicator capable of discriminating estrogen agonists from antagonists in living cells.
Analytical chemistry 2004;76(8):2181-6.
2004: Yuko Yamaguchi; Mineo Kurokawa; Yoichi Imai; Koji Izutsu; Takashi Asai; Motoshi Ichikawa; Go Yamamoto; Eriko Nitta; Tetsuya Yamagata; Kazuki Sasaki; Kinuko Mitani; Seishi Ogawa; Shigeru Chiba; Hisamaru Hirai
AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues.
The Journal of biological chemistry 2004;279(15):15630-8.
2003: Kazuki Sasaki; Moritoshi Sato; Yoshio Umezawa
Fluorescent indicators for Akt/protein kinase B and dynamics of Akt activity visualized in living cells.
The Journal of biological chemistry 2003;278(33):30945-51.
2002: Takao Ohkubo; Yasuhiko Sugawara; Kazuki Sasaki; Kouji Maruyama; Naganari Ohkura; Makuuchi Masatoshi
Early induction of nerve growth factor-induced genes after liver resection-reperfusion injury.
Journal of hepatology 2002;36(2):210-7.
2001: Akira Togayachi; Tomohiro Akashima; R Ookubo; Takashi Kudo; Shoko Nishihara; Hiroko Iwasaki; A Natsume; H Mio; J Inokuchi ; Tatsuro Irimura; Kazuki Sasaki; Hisashi Narimatsu
Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids.
The Journal of biological chemistry 2001;276(25):22032-40.
2001: F Nakayama; Shoko Nishihara; Hiroko Iwasaki; Takashi Kudo; Reiko Okubo; Michiyo Kaneko; Masaki Nakamura; M Karube; Kazuki Sasaki; Hisashi Narimatsu
CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV.
The Journal of biological chemistry 2001;276(19):16100-6.
2001: N Shiraishi; A Natsume; Akira Togayachi; T Endo; Tomohiro Akashima; Y Yamada; N Imai; S Nakagawa; S Koizumi; S Sekine; Hisashi Narimatsu; Kazuki Sasaki
Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family.
The Journal of biological chemistry 2001;276(5):3498-507.
2001: T Homma; Osamu Hosono; Satoshi Iwata; S Ando; Kazuki Sasaki; T Nishi; Hiroshi Kawasaki; Hirotoshi Tanaka; Chikao Morimoto
Recognition of cell surface GD3 by monoclonal antibody anti-6C2 in rheumatoid arthritis synovial fluid: expression on human T cells with transendothelial migratory activity.
Arthritis and rheumatism 2001;44(2):296-306.
2000: Hiroo Ueno; E Kondo; Ritsuko Yamamoto-Honda; Kazuyuki Tobe; Tetsuya Nakamoto; Kazuki Sasaki; Kinuko Mitani; A Furusaka; Toshihiro Tanaka; Y Tsujimoto; Takashi Kadowaki; Hisamura Hirai
Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function.
Molecular biology of the cell 2000;11(2):735-46.
1999: Michiyo Kaneko; Takashi Kudo; Hiroko Iwasaki; Yuzuru Ikehara; Shoko Nishihara; S Nakagawa; Kazuki Sasaki; T Shiina; Hidetoshi Inoko; Naruya Saitou; Hisashi Narimatsu
Alpha1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX.
FEBS letters 1999;452(3):237-42.
1999: S Isshiki; Akira Togayachi; Takashi Kudo; Shoko Nishihara; Masahiko Watanabe; T Kubota; M Kitajima; N Shiraishi; Kazuki Sasaki; T Andoh; Hisashi Narimatsu
Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom.
The Journal of biological chemistry 1999;274(18):12499-507.
1998: Takashi Kudo; Yuzuru Ikehara; Akira Togayachi; Michiyo Kaneko; T Hiraga; Kazuki Sasaki; Hisashi Narimatsu
Expression cloning and characterization of a novel murine alpha1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney.
The Journal of biological chemistry 1998;273(41):26729-38.
1998: Hiroo Ueno; Kazuki Sasaki; Hiroaki Honda; Tetsuya Nakamoto; Tetsuya Yamagata; Kiyoshi Miyagawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
c-Cbl is tyrosine-phosphorylated by interleukin-4 and enhances mitogenic and survival signals of interleukin-4 receptor by linking with the phosphatidylinositol 3'-kinase pathway.
Blood 1998;91(1):46-53.
1997: Kazuki Sasaki; K Kurata-Miura; M Ujita; K Angata; S Nakagawa; S Sekine; T Nishi; M Fukuda
Expression cloning of cDNA encoding a human beta-1,3-N-acetylglucosaminyltransferase that is essential for poly-N-acetyllactosamine synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14294-9.
1997: K Shinoda; Y Morishita; Kazuki Sasaki; Y Matsuda; I Takahashi; T Nishi
Enzymatic characterization of human alpha1,3-fucosyltransferase Fuc-TVII synthesized in a B cell lymphoma cell line.
The Journal of biological chemistry 1997;272(51):31992-7.
1997: Akeo Shinkai; K Shinoda; Kazuki Sasaki; Y Morishita; T Nishi; Y Matsuda; I Takahashi; Hideharu Anazawa
High-level expression and purification of a recombinant human alpha-1, 3-fucosyltransferase in baculovirus-infected insect cells.
Protein expression and purification 1997;10(3):379-85.
1997: Hiroo Ueno; Hiroaki Honda; Tetsuya Nakamoto; Tetsuya Yamagata; Kazuki Sasaki; Kiyoshi Miyagawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase.
Oncogene 1997;14(25):3067-72.
1997: H Odai; Kazuki Sasaki; A Iwamatsu; Tetsuya Nakamoto; Hiroo Ueno; Tetsuya Yamagata; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl.
Blood 1997;89(8):2745-56.
1997: H Odai; Y Hanazono; Kazuki Sasaki; A Iwamatu; Yoshio Yazaki; Hisamura Hirai
The signal transduction through Grb2/Ash in hematopoietic cells.
Leukemia 1997;11 Suppl 3():405-7.
1997: Hiroo Ueno; Kazuki Sasaki; Kiyoshi Miyagawa; Hiroaki Honda; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling.
The Journal of biological chemistry 1997;272(13):8739-43.
1996: Hiroo Ueno; Kazuki Sasaki; H Kozutsumi; K Miyagawa; Kinuko Mitani; Y Yazaki; H Hirai
Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase.
The Journal of biological chemistry 1996;271(44):27707-14.
1996: E Nishimura; Kazuki Sasaki; K Maruyama; T Tsukada; K Yamaguchi
Decrease in neuron-restrictive silencer factor (NRSF) mRNA levels during differentiation of cultured neuroblastoma cells.
Neuroscience letters 1996;211(2):101-4.
1996: Y Hanazono; Kazuki Sasaki; H Odai; Y Yazaki; H Hirai
Tyrosine phosphorylation of a 94-kDa protein associated with GRB2/ASH is implicated in the signal transduction of hematopoietic survival factors.
Biochemical and biophysical research communications 1996;222(2):330-7.
1996: Y Hanazono; H Odai; Kazuki Sasaki; A Iwamatsu; Y Yazaki; H Hirai
Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells.
Acta haematologica 1996;95(3-4):236-42.
1995: H Odai; Kazuki Sasaki; Y Hanazono; Hiroo Ueno; T Tanaka; K Miyagawa; Kinuko Mitani; Y Yazaki; H Hirai
c-Cbl is inducibly tyrosine-phosphorylated by epidermal growth factor stimulation in fibroblasts, and constitutively tyrosine-phosphorylated and associated with v-Src in v-src-transformed fibroblasts.
Japanese journal of cancer research : Gann 1995;86(12):1119-26.
1995: Kazuki Sasaki; H Odai; Y Hanazono; Hiroo Ueno; Seishi Ogawa; W Y Langdon; T Tanaka; K Miyagawa; Kinuko Mitani; Y Yazaki
TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules.
Biochemical and biophysical research communications 1995;216(1):338-47.
1995: Hiroo Ueno; Naoto Hirano; H Kozutsumi; Kazuki Sasaki; T Tanaka; Y Yazaki; H Hirai
An epidermal growth factor receptor-leukocyte tyrosine kinase chimeric receptor generates ligand-dependent growth signals through the Ras signaling pathway.
The Journal of biological chemistry 1995;270(34):20135-42.
1995: H Odai; Kazuki Sasaki; A Iwamatsu; Y Hanazono; T Tanaka; Kinuko Mitani; Y Yazaki; H Hirai
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells.
The Journal of biological chemistry 1995;270(18):10800-5.
1995: Y Hanazono; Kazuki Sasaki; H Odai; Toshihide Mimura; Kinuko Mitani; Y Yazaki; H Hirai
Tyrosine phosphorylation of the proto-oncogene product Vav and its association with the adapter Grb2/Ash in a human leukemia cell line UT-7.
Japanese journal of cancer research : Gann 1995;86(4):336-41.
1995: Y Hanazono; Kazuki Sasaki; H Nitta; Y Yazaki; H Hirai
Erythropoietin induces tyrosine phosphorylation of the beta chain of the GM-CSF receptor.
Biochemical and biophysical research communications 1995;208(3):1060-6.
1994: Kazuki Sasaki; K Kurata; N Kojima; N Kurosawa; S Ohta; Nobuo Hanai; S Tsuji; T Nishi
Expression cloning of a GM3-specific alpha-2,8-sialyltransferase (GD3 synthase).
The Journal of biological chemistry 1994;269(22):15950-6.
1994: Kazuki Sasaki; K Kurata; K Funayama; M Nagata; E Watanabe; S Ohta; Nobuo Hanai; T Nishi
Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes.
The Journal of biological chemistry 1994;269(20):14730-7.
1993: Kazuki Sasaki; E Watanabe; K Kawashima; S Sekine; T Dohi; M Oshima; Nobuo Hanai; T Nishi; M Hasegawa
Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection.
The Journal of biological chemistry 1993;268(30):22782-7.
1993: Kazuki Sasaki; Shigeru Chiba; Y Hanazono; H Mano; Y Yazaki; H Hirai
Coordinate expression of the alpha and beta chains of human granulocyte-macrophage colony-stimulating factor receptor confers ligand-induced morphological transformation in mouse fibroblasts.
The Journal of biological chemistry 1993;268(18):13697-702.
1993: Y Hanazono; Shigeru Chiba; Kazuki Sasaki; H Mano; Y Yazaki; H Hirai
Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells.
Blood 1993;81(12):3193-6.
1993: Y Hanazono; Shigeru Chiba; Kazuki Sasaki; H Mano; Atsushi Miyajima; K i Arai; Y Yazaki; H Hirai
c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3.
The EMBO journal 1993;12(4):1641-6.
1992: Kazuki Sasaki; Shigeru Chiba; H Mano; Y Yazaki; H Hirai
Identification of a soluble GM-CSF binding protein in the supernatant of a human choriocarcinoma cell line.
Biochemical and biophysical research communications 1992;183(1):252-7.
1991: Shigeru Chiba; F Takaku; Tsuyoshi Tange; K Shibuya; C Misawa; Kazuki Sasaki; K Miyagawa; Y Yazaki; H Hirai
Establishment and erythroid differentiation of a cytokine-dependent human leukemic cell line F-36: a parental line requiring granulocyte-macrophage colony-stimulating factor or interleukin-3, and a subline requiring erythropoietin.
Blood 1991;78(9):2261-8.