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Takashi Sato

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Chemicals & Drugs

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Cricetinae

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Fibrosarcoma

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Takashi Sato; Noriko Akimoto; Nobukazu Hayashi; Kimiko Kitamura; Hirokazu Kurihara; Akira Ito
Adapalene suppresses sebum accumulation via the inhibition of triacylglycerol biosynthesis and perilipin expression in differentiated hamster sebocytes in vitro.
Hirokazu Kurihara; Takashi Sato; Noriko Akimoto; Akira Ito
Differentiated hamster sebocytes exhibit apoptosis-resistant phenotype by the augmentation of intracellular calcium level in vitro.
Takashi Sato; Tatsuhiko Shirane; Norihisa Noguchi; Masanori Sasatsu; Akira Ito
Novel anti-acne actions of nadifloxacin and clindamycin that inhibit the production of sebum, prostaglandin E(2) and promatrix metalloproteinase-2 in hamster sebocytes.

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All Publications

2013: Takashi Sato; Noriko Akimoto; Nobukazu Hayashi; Kimiko Kitamura; Hirokazu Kurihara; Akira Ito
Adapalene suppresses sebum accumulation via the inhibition of triacylglycerol biosynthesis and perilipin expression in differentiated hamster sebocytes in vitro.
Journal of dermatological science 2013;70(3):204-10.
2013: Hirokazu Kurihara; Takashi Sato; Noriko Akimoto; Akira Ito
Differentiated hamster sebocytes exhibit apoptosis-resistant phenotype by the augmentation of intracellular calcium level in vitro.
Experimental dermatology 2013;22(1):57-9.
2012: Takashi Sato; Tatsuhiko Shirane; Norihisa Noguchi; Masanori Sasatsu; Akira Ito
Novel anti-acne actions of nadifloxacin and clindamycin that inhibit the production of sebum, prostaglandin E(2) and promatrix metalloproteinase-2 in hamster sebocytes.
The Journal of dermatology 2012;39(9):774-80.
2012: Takashi Sato; Mami Watanabe; Motoyoshi Nomizu; Tomoko Ota; Noriko Akimoto; Kei Hashimoto; Keisuke Imada; Akira Ito
A novel functional site of extracellular matrix metalloproteinase inducer (EMMPRIN) that limits the migration of human uterine cervical carcinoma cells.
International journal of oncology 2012;40(1):236-42.
2011: Takashi Sato; Hirokazu Kurihara; Noriko Akimoto; Norihisa Noguchi; Masanori Sasatsu; Akira Ito
Augmentation of gene expression and production of promatrix metalloproteinase 2 by Propionibacterium acnes-derived factors in hamster sebocytes and dermal fibroblasts: a possible mechanism for acne scarring.
Biological & pharmaceutical bulletin 2011;34(2):295-9.
2010: Katsuhiro Iinuma; Takashi Sato; Noriko Akimoto; Hirokazu Kurihara; Akira Ito
Induction of inflammatory reactions by lipopolysaccharide in hamster sebaceous glands and pilosebaceous units in vivo and in vitro.
Experimental dermatology 2010;19(12):1107-9.
2010: Keisuke Imada; Hideki Oka; Daisuke Kawasaki; Naoyoshi Miura; Takashi Sato; Akira Ito
Anti-arthritic action mechanisms of natural chondroitin sulfate in human articular chondrocytes and synovial fibroblasts.
Biological & pharmaceutical bulletin 2010;33(3):410-4.
2009: Katsuhiro Iinuma; Takashi Sato; Noriko Akimoto; Norihisa Noguchi; Masanori Sasatsu; Setsuko Nishijima; Ichiro Kurokawa; Akira Ito
Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro.
The Journal of investigative dermatology 2009;129(9):2113-9.
2009: Takashi Sato; Tomoko Ota; Mami Watanabe; Keisuke Imada; Motoyoshi Nomizu; Akira Ito
Identification of an active site of EMMPRIN for the augmentation of matrix metalloproteinase-1 and -3 expression in a co-culture of human uterine cervical carcinoma cells and fibroblasts.
Gynecologic oncology 2009;114(2):337-42.
2009: Tomofumi Fujino; Kaori Murakami; Issei Ozawa; Yoshie Minegishi; Ryo Kashimura; Toshihiro Akita; Susumu Saitou; Takehisa Atsumi; Takashi Sato; Ken Ando; Shuntaro Hara; Kiyomi Kikugawa; Makio Hayakawa
Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway.
The FEBS journal 2009;276(5):1319-32.
2008: Keisuke Imada; Na Lin; Chunfang Liu; Aiping Lu; Weiheng Chen; Masamichi Yano; Takashi Sato; Akira Ito
Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice.
Biochemical and biophysical research communications 2008;373(2):181-5.
2008: Yoshiki Miyata; Takashi Sato; Keisuke Imada; Akira Dobashi; Masamichi Yano; Akira Ito
A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells.
Biochemical and biophysical research communications 2008;366(1):168-73.
2007: Takashi Sato; Aiko Takahashi; Mika Kojima; Noriko Akimoto; Masamichi Yano; Akira Ito
A citrus polymethoxy flavonoid, nobiletin inhibits sebum production and sebocyte proliferation, and augments sebum excretion in hamsters.
The Journal of investigative dermatology 2007;127(12):2740-8.
2005: Yoshiki Miyata; Takashi Sato; Akira Ito
Triptolide, a diterpenoid triepoxide, induces antitumor proliferation via activation of c-Jun NH2-terminal kinase 1 by decreasing phosphatidylinositol 3-kinase activity in human tumor cells.
Biochemical and biophysical research communications 2005;336(4):1081-6.
2005: Chikakazu Iwata; Noriko Akimoto; Takashi Sato; Yuki Morokuma; Akira Ito
Augmentation of lipogenesis by 15-deoxy-Delta12,14-prostaglandin J2 in hamster sebaceous glands: identification of cytochrome P-450-mediated 15-deoxy-Delta12,14-prostaglandin J2 production.
The Journal of investigative dermatology 2005;125(5):865-72.
2005: Noriko Akimoto; Takashi Sato; Chikakazu Iwata; Masayuki Koshizuka; Fusatoshi Shibata; Ayako Nagai; Michihiro Sumida; Akira Ito
Expression of perilipin A on the surface of lipid droplets increases along with the differentiation of hamster sebocytes in vivo and in vitro.
The Journal of investigative dermatology 2005;124(6):1127-33.
2004: Sachiko Tanaka; Takashi Sato; Noriko Akimoto; Masamichi Yano; Akira Ito
Prevention of UVB-induced photoinflammation and photoaging by a polymethoxy flavonoid, nobiletin, in human keratinocytes in vivo and in vitro.
Biochemical pharmacology 2004;68(3):433-9.
2004: Yoshiki Miyata; Takashi Sato; Masamichi Yano; Akira Ito
Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin.
Molecular cancer therapeutics 2004;3(7):839-47.
2004: Takashi Sato; Takeaki Sakai; Yutaka Noguchi; Morichika Takita; Shun Hirakawa; Akira Ito
Tumor-stromal cell contact promotes invasion of human uterine cervical carcinoma cells by augmenting the expression and activation of stromal matrix metalloproteinases.
Gynecologic oncology 2004;92(1):47-56.
2003: Yutaka Noguchi; Takashi Sato; Michiko Hirata; Tetsuaki Hara; Koso Ohama; Akira Ito
Identification and characterization of extracellular matrix metalloproteinase inducer in human endometrium during the menstrual cycle in vivo and in vitro.
The Journal of clinical endocrinology and metabolism 2003;88(12):6063-72.
2003: Michiko Hirata; Takashi Sato; Michiko Tsumagari; Kazuyoshi Hashizume; Akira Ito
Discoordinate regulation of expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases-3 in bovine endometrial stromal cells on type-I collagen gel.
Biological & pharmaceutical bulletin 2003;26(7):1013-7.
2003: Na Lin; Takashi Sato; Yuji Takayama; Yoshihiro Mimaki; Yutaka Sashida; Masamichi Yano; Akira Ito
Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages.
Biochemical pharmacology 2003;65(12):2065-71.
2003: Michiko Hirata; Takashi Sato; Michiko Tsumagari; Arata Shimada; Haruo Nakano; Kazuyoshi Hashizume; Akira Ito
Differential regulation of the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases by cytokines and growth factors in bovine endometrial stromal cells and trophoblast cell line BT-1 in vitro.
Biology of reproduction 2003;68(4):1276-81.
2002: Keisuke Imada; Takashi Sato; Kazuyoshi Hashizume; Akihide Tanimoto; Yasuyuki Sasaguri; Akira Ito
An antiprogesterone, onapristone, enhances the gene expression of promatrix metalloproteinase 3/prostromelysin-1 in the uterine cervix of pregnant rabbit.
Biological & pharmaceutical bulletin 2002;25(9):1223-7.
2002: Y Sawaji; Takashi Sato; A Takeuchi; Michiko Hirata; Akira Ito
Anti-angiogenic action of hyperthermia by suppressing gene expression and production of tumour-derived vascular endothelial growth factor in vivo and in vitro.
British journal of cancer 2002;86(10):1597-603.
2002: Takashi Sato; Leona Koike; Yoshiki Miyata; Michiko Hirata; Yoshihiro Mimaki; Yutaka Sashida; Masamichi Yano; Akira Ito
Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells.
Cancer research 2002;62(4):1025-9.
2002: Noriko Akimoto; Takashi Sato; T Sakiguchi; K Kitamura; Y Kohno; Akira Ito
Cell proliferation and lipid formation in hamster sebaceous gland cells.
Dermatology (Basel, Switzerland) 2002;204(2):118-23.
2001: Takashi Sato; N Imai; Noriko Akimoto; T Sakiguchi; K Kitamura; Akira Ito
Epidermal growth factor and 1alpha,25-dihydroxyvitamin D3 suppress lipogenesis in hamster sebaceous gland cells in vitro.
The Journal of investigative dermatology 2001;117(4):965-70.
2000: H Akimoto; R Yamazaki; S Hashimoto; Takashi Sato; Akira Ito
4'-Hydroxy aceclofenac suppresses the interleukin-1-induced production of promatrix metalloproteinases and release of sulfated-glycosaminoglycans from rabbit articular chondrocytes.
European journal of pharmacology 2000;401(3):429-36.
2000: Y Sawaji; Takashi Sato; Motoharu Seiki; Akira Ito
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Clinical & experimental metastasis 2000;18(2):131-8.
2000: J Ishiwa; Takashi Sato; Yoshihiro Mimaki; Yutaka Sashida; Masamichi Yano; Akira Ito
A citrus flavonoid, nobiletin, suppresses production and gene expression of matrix metalloproteinase 9/gelatinase B in rabbit synovial fibroblasts.
The Journal of rheumatology 2000;27(1):20-5.
1999: Takashi Sato; T Kondo; T Fujisawa; Motoharu Seiki; Akira Ito
Furin-independent pathway of membrane type 1-matrix metalloproteinase activation in rabbit dermal fibroblasts.
The Journal of biological chemistry 1999;274(52):37280-4.
1999: Takashi Sato; Y Sawaji; N Matsui; H Sato; Motoharu Seiki; Y Mori; Akira Ito
Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion.
Biochemical and biophysical research communications 1999;265(1):189-93.
1999: Takashi Sato; T Kondo; Motoharu Seiki; Akira Ito
Cell type-specific involvement of furin in membrane type 1 matrix metalloproteinase-mediated progelatinase A activation.
Annals of the New York Academy of Sciences 1999;878():713-5.
1999: Y Sawaji; Takashi Sato; Motoharu Seiki; Akira Ito
Transient increase of intracellular cAMP by heat shock initiates the suppression of MT1-MMP production in tumor cells.
Annals of the New York Academy of Sciences 1999;878():707-9.
1999: Akira Ito; J Ishiwa; Takashi Sato; Y Mimaki; Y Sashida
The citrus flavonoid nobiletin suppresses the production and gene expression of matrix metalloproteinases-9/gelatinase B in rabbit synovial cells.
Annals of the New York Academy of Sciences 1999;878():632-4.
1999: Takashi Sato; M Iwai; T Sakai; H Sato; Motoharu Seiki; Y Mori; Akira Ito
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
British journal of cancer 1999;80(8):1137-43.
1998: Akira Ito; M Yamada; Takashi Sato; K Sanekata; H Sato; Motoharu Seiki; H Nagase; Y Mori
Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts.
European journal of biochemistry / FEBS 1998;251(1-2):353-8.
1997: Takashi Sato; Y Kirimura; Y Mori
The co-culture of dermal fibroblasts with human epidermal keratinocytes induces increased prostaglandin E2 production and cyclooxygenase 2 activity in fibroblasts.
The Journal of investigative dermatology 1997;109(3):334-9.
1997: K Imada; Akira Ito; Takashi Sato; M Namiki; H Nagase; Y Mori
Hormonal regulation of matrix metalloproteinase 9/gelatinase B gene expression in rabbit uterine cervical fibroblasts.
Biology of reproduction 1997;56(3):575-80.
1996: Takashi Sato; Akira Ito; Y Ogata; H Nagase; Y Mori
Tumor necrosis factor alpha (TNFalpha) induces pro-matrix metalloproteinase 9 production in human uterine cervical fibroblasts but interleukin 1alpha antagonizes the inductive effect of TNFalpha.
FEBS letters 1996;392(2):175-8.