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Quentin Sattentau

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Frank Wegmann; Adam Williams; Erin M Scherer; Neil C Sheppard; Catharina Svanborg; Joseph N Blattman; Sarah A Brinckmann; Margherita Coccia; Suzanne Cole; Richard A Flavell; Kate H Gartlan; Philip D Greenberg; Ali M Harandi; William R Hillson; Ling-Pei Ho; Wai Ling Kok; George Krashias; Teresa Lambe; Amin E Moghaddam; Manoj Puthia; Quentin J Sattentau
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens.
Quentin J Sattentau
The direct passage of animal viruses between cells.
Sara Pruzina; Quentin J Sattentau; Sueli M Vieira; Gareth T Williams; Marianne Brüggemann; Sarah L Davies; Simon A Jeffs; Galina Kaneva; Alicia Martín-López; Michael S Neuberger
Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci.

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All Publications

2012: Frank Wegmann; Adam Williams; Erin M Scherer; Neil C Sheppard; Catharina Svanborg; Joseph N Blattman; Sarah A Brinckmann; Margherita Coccia; Suzanne Cole; Richard A Flavell; Kate H Gartlan; Philip D Greenberg; Ali M Harandi; William R Hillson; Ling-Pei Ho; Wai Ling Kok; George Krashias; Teresa Lambe; Amin E Moghaddam; Manoj Puthia; Quentin J Sattentau
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens.
Nature biotechnology 2012;30(9):883-8.
2011: Quentin J Sattentau
The direct passage of animal viruses between cells.
Current opinion in virology 2011;1(5):396-402.
2011: Sara Pruzina; Quentin J Sattentau; Sueli M Vieira; Gareth T Williams; Marianne Brüggemann; Sarah L Davies; Simon A Jeffs; Galina Kaneva; Alicia Martín-López; Michael S Neuberger
Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci.
Protein engineering, design & selection : PEDS 2011;24(10):791-9.
2011: Clare Jolly; Stefanie Michor; Sonja Welsch; Quentin J Sattentau
The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse.
PLoS pathogens 2011;7(9):e1002226.
2011: Amin E Moghaddam; Kate H Gartlan; Leopold Kong; Quentin J Sattentau
Reactive carbonyls are a major Th2-inducing damage-associated molecular pattern generated by oxidative stress.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1626-33.
2011: Sonja Welsch; Fedde Groot; Oliver T Keppler; Hans-Georg Kräusslich; Quentin J Sattentau
Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.
Journal of virology 2011;85(15):7922-7.
2011: Frank Wegmann; George Krashias; Kerstin Lühn; Karoliina Laamanen; Sueli Vieira; Simon A Jeffs; Robin J Shattock; Quentin J Sattentau
A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment.
PloS one 2011;6(1):e15861.
2010: Leopold Kong; Neil C Sheppard; Guillaume B E Stewart-Jones; Cynthia L Robson; Hongying Chen; Xiaodong Xu; George Krashias; Camille Bonomelli; Christopher N Scanlan; Peter D Kwong; Simon A Jeffs; Ian M Jones; Quentin J Sattentau
Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.
Journal of molecular biology 2010;403(1):131-47.
2010: Quentin J Sattentau
Cell-to-Cell Spread of Retroviruses.
Viruses 2010;2(6):1306-21.
2010: Nuria González; Mercedes Bermejo; Esther Calonge; Clare Jolly; Fernando Arenzana-Seisdedos; José L Pablos; Quentin J Sattentau; José Alcamí
SDF-1/CXCL12 production by mature dendritic cells inhibits the propagation of X4-tropic HIV-1 isolates at the dendritic cell-T-cell infectious synapse.
Journal of virology 2010;84(9):4341-51.
2010: Quentin J Sattentau
Retroviruses and the third synapse.
Viruses 2010;2(4):1008-10.
2010: Nicola Martin; Sonja Welsch; Clare Jolly; John A G Briggs; David Vaux; Quentin J Sattentau
Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition.
Journal of virology 2010;84(7):3516-27.
2010: George Krashias; Anna-Katharina Simon; Frank Wegmann; Wai-Ling Kok; Ling-Pei Ho; David Stevens; John Skehel; Jonathan Luke Heeney; Amin E Moghaddam; Quentin J Sattentau
Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer.
Vaccine 2010;28(13):2482-9.
2010: Quentin J Sattentau; Andrew J McMichael
New templates for HIV-1 antibody-based vaccine design.
F1000 biology reports 2010;2():60.
2010: Davide Corti; Johannes P M Langedijk; Andreas Hinz; Michael S Seaman; Fabrizia Vanzetta; Blanca M Fernandez-Rodriguez; Chiara Silacci; Debora Pinna; David Jarrossay; Sunita Balla-Jhagjhoorsingh; Betty Willems; Maria J Zekveld; Hanna Dreja; Eithne O'Sullivan; Corinna Pade; Chloe Orkin; Simon A Jeffs; David C Montefiori; David Davis; Winfried Weissenhorn; Aine McKnight; Jonathan Luke Heeney; Federica Sallusto; Quentin J Sattentau; Robin A Weiss; Antonio Lanzavecchia
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.
PloS one 2010;5(1):e8805.
2009: Daniela Romer; David W Brighty; Cynthia L Robson; Quentin J Sattentau
Candidate polyanionic microbicides inhibit human T-cell lymphotropic virus type 1 receptor interactions, cell-free infection, and cell-cell spread.
Antimicrobial agents and chemotherapy 2009;53(2):678-87.
2008: Quentin J Sattentau
Avoiding the void: cell-to-cell spread of human viruses.
Nature reviews. Microbiology 2008;6(11):815-26.
2008: Fedde Groot; Sonja Welsch; Quentin J Sattentau
Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.
Blood 2008;111(9):4660-3.
2008: Quentin J Sattentau
HIV's gut feeling.
Nature immunology 2008;9(3):225-7.
2008: Stefanie Sowinski; Clare Jolly; Otto Berninghausen; Marco A Purbhoo; Anne Chauveau; Karsten Köhler; Stephane Oddos; Philipp Eissmann; Frances M Brodsky; Colin Hopkins; Björn Onfelt; Quentin J Sattentau; Daniel M Davis
Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission.
Nature cell biology 2008;10(2):211-9.
2007: David Montefiori; Quentin J Sattentau; Jorge Flores; José Esparza; John R Mascola
Antibody-based HIV-1 vaccines: recent developments and future directions.
PLoS medicine 2007;4(12):e348.
2007: Clare Jolly; Ivonne Mitar; Quentin J Sattentau
Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells.
Journal of virology 2007;81(24):13916-21.
2007: Clare Jolly; Quentin J Sattentau
Regulated secretion from CD4+ T cells.
Trends in immunology 2007;28(11):474-81.
2007: Katherine E Gantlett; Jonathan N Weber; Quentin J Sattentau
Synergistic inhibition of HIV-1 infection by combinations of soluble polyanions with other potential microbicides.
Antiviral research 2007;75(3):188-97.
2007: Clare Jolly; Quentin J Sattentau
Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane domains.
Journal of virology 2007;81(15):7873-84.
2007: Clare Jolly; Ivonne Mitar; Quentin J Sattentau
Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.
Journal of virology 2007;81(11):5547-60.
2007: Neil C Sheppard; Anna C Bates; Quentin J Sattentau
A functional human IgM response to HIV-1 Env after immunization with NYVAC HIV C.
AIDS (London, England) 2007;21(4):524-7.
2007: Neil C Sheppard; Sarah L Davies; Simon A Jeffs; Sueli M Vieira; Quentin J Sattentau
Production and characterization of high-affinity human monoclonal antibodies to human immunodeficiency virus type 1 envelope glycoproteins in a mouse model expressing human immunoglobulins.
Clinical and vaccine immunology : CVI 2007;14(2):157-67.
2006: giulia zanetti; John A G Briggs; Kay Grünewald; Quentin J Sattentau; Stephen D Fuller
Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ.
PLoS pathogens 2006;2(8):e83.
2006: Amin Moghaddam; Wieslawa Olszewska; Belinda Wang; John Tregoning; Rebecca Helson; Quentin J Sattentau; Peter J M Openshaw
A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines.
Nature medicine 2006;12(8):905-7.
2005: Thomas Lehner; Michael Hoelscher; Mario Clerici; Frances Gotch; Louise Pedneault; Jim Tartaglia; Clive Gray; Jiri Mestecky; Quentin J Sattentau; Janneke van de Wijgert; Coumba Toure; Saladin Osmanov; Reinold E Schmidt; Patrice Debre; Manuel Romaris; Arnd Hoeveler; Simonetta Di Fabio
European Union and EDCTP strategy in the global context: recommendations for preventive HIV/AIDS vaccines research.
Vaccine 2005;23(48-49):5551-6.
2005: Tongqing Zhou; Dean H Hamer; Wayne A Hendrickson; Quentin J Sattentau; Peter D Kwong
Interfacial metal and antibody recognition.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14575-80.
2005: Clare Jolly; Quentin J Sattentau
Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity.
Journal of virology 2005;79(18):12088-94.
2005: Romain R Vivès; Anne Imberty; Quentin J Sattentau; Hugues Lortat-Jacob
Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.
The Journal of biological chemistry 2005;280(22):21353-7.
2005: N Avrion Mitchison; Quentin J Sattentau
Fundamental immunology and what it can teach us about HIV vaccine development.
Current drug targets. Infectious disorders 2005;5(2):87-93.
2005: Neil C Sheppard; Quentin J Sattentau
The prospects for vaccines against HIV-1: more than a field of long-term nonprogression?
Expert reviews in molecular medicine 2005;7(2):1-21.
2005: Oliver Hartley; Per Johan Klasse; Quentin J Sattentau; John P Moore
V3: HIV's switch-hitter.
AIDS research and human retroviruses 2005;21(2):171-89.
2005: David R Morcock; James A Thomas; Tracy D Gagliardi; Robert J Gorelick; James D Roser; Elena Chertova; Julian W Bess; David E Ott; Quentin J Sattentau; Ines Frank; Melissa Pope; Jeffrey D Lifson; Louis E. Henderson; Bruce J Crise
Elimination of retroviral infectivity by N-ethylmaleimide with preservation of functional envelope glycoproteins.
Journal of virology 2005;79(3):1533-42.
2004: vincent piguet; Quentin J Sattentau
Dangerous liaisons at the virological synapse.
The Journal of clinical investigation 2004;114(5):605-10.
2004: Clare Jolly; Quentin J Sattentau
Retroviral spread by induction of virological synapses.
Traffic (Copenhagen, Denmark) 2004;5(9):643-50.
2004: SA Jeffs; S Goriup; B Kebble; Dennis Crane; Barbara Bolgiano; Quentin J Sattentau; S Jones; Harvey Holmes
Expression and characterisation of recombinant oligomeric envelope glycoproteins derived from primary isolates of HIV-1.
Vaccine 2004;22(8):1032-46.
2004: Clare Jolly; Kirk Kashefi; Michael Hollinshead; Quentin J Sattentau
HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse.
The Journal of experimental medicine 2004;199(2):283-93.
2003: Makobetsa Khati; Michael Schüman; jamal ibrahim; Quentin J Sattentau; Siamon Gordon; William James
Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2'F-RNA aptamers.
Journal of virology 2003;77(23):12692-8.
2003: Josefina D Piñon; Per Johan Klasse; Sushma Jassal; Sandy Welson; Jonathan Weber; David W Brighty; Quentin J Sattentau
Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans.
Journal of virology 2003;77(18):9922-30.
2002: Per Johan Klasse; Quentin J Sattentau
Occupancy and mechanism in antibody-mediated neutralization of animal viruses.
The Journal of general virology 2002;83(Pt 9):2091-108.
2001: Per Johan Klasse; Quentin J Sattentau
Mechanisms of virus neutralization by antibody.
Current topics in microbiology and immunology 2001;260():87-108.
2000: Peter D Kwong; Richard Wyatt; Quentin J Sattentau; Joseph Sodroski; Wayne A Hendrickson
Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus.
Journal of virology 2000;74(4):1961-72.
2000: Maxime Moulard; Hugues Lortat-Jacob; I Mondor; G Roca; Richard Wyatt; Joseph Sodroski; L Zhao; W Olson; Peter D Kwong; Quentin J Sattentau
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120.
Journal of virology 2000;74(4):1948-60.
2000: Agnes Chenine; Quentin J Sattentau; M Moulard
Selective HIV-1-induced downmodulation of CD4 and coreceptors.
Archives of virology 2000;145(3):455-71.
2000: Galina Denisova; M Zerwanitzer; Dmitri Denisov; Evgenia Spectorman; I Mondor; Quentin J Sattentau; Jonathan M Gershoni
Expansion of epitope cross-reactivity by anti-idiotype modulation of the primary humoral response.
Molecular immunology 2000;37(1-2):53-8.
1999: Xiaodong Xiao; L Wu; Tzanko S Stantchev; Yan-Ru Feng; S Ugolini; H Chen; Z Shen; James L Riley; Christopher C Broder; Quentin J Sattentau; Dimiter S Dimitrov
Constitutive cell surface association between CD4 and CCR5.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7496-501.
1999: MARK ESSER; T Mori; I Mondor; Quentin J Sattentau; Barna Dey; Edward A Berger; M R Boyd; Jeffrey D Lifson
Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.
Journal of virology 1999;73(5):4360-71.
1999: S Ugolini; I Mondor; Quentin J Sattentau
HIV-1 attachment: another look.
Trends in microbiology 1999;7(4):144-9.
1999: Quentin J Sattentau; Maxime Moulard; B Brivet; F Botto; J C Guillemot; I Mondor; Pascal Poignard; S Ugolini
Antibody neutralization of HIV-1 and the potential for vaccine design.
Immunology letters 1999;66(1-3):143-9.
1999: Paul W H I Parren; John P Moore; Dennis R Burton; Quentin J Sattentau
The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity.
AIDS (London, England) 1999;13 Suppl A():S137-62.
1998: Jeffrey L Rossio; MARK ESSER; K Suryanarayana; Douglas K Schneider; Julian W Bess; GM Vasquez; TA Wiltrout; Elena Chertova; M K Grimes; Quentin J Sattentau; Larry O Arthur; Louis E. Henderson; Jeffrey D Lifson
Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.
Journal of virology 1998;72(10):7992-8001.
1998: I Mondor; Maxime Moulard; S Ugolini; Per Johan Klasse; James A Hoxie; Ali Amara; Thierry Delaunay; Richard Wyatt; Joseph Sodroski; Quentin J Sattentau
Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.
Virology 1998;248(2):394-405.
1998: Quentin J Sattentau
HIV gp120: double lock strategy foils host defences.
Structure (London, England : 1993) 1998;6(8):945-9.
1998: N Sullivan; YanPing Sun; Quentin J Sattentau; M Thali; D Wu; Galina Denisova; Jonathan M Gershoni; J Robinson; J Moore; Joseph Sodroski
CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization.
Journal of virology 1998;72(6):4694-703.
1998: I Mondor; S Ugolini; Quentin J Sattentau
Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans.
Journal of virology 1998;72(5):3623-34.
1998: Paul W H I Parren; I Mondor; Denise Naniche; Henrik J Ditzel; Per Johan Klasse; Dennis R Burton; Quentin J Sattentau
Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity.
Journal of virology 1998;72(5):3512-9.
1998: Edward A Berger; R W Doms; E M Fenyö; B T Korber; Dan R Littman; J P Moore; Quentin J Sattentau; H Schuitemaker; Joseph Sodroski; R A Weiss
A new classification for HIV-1.
Nature 1998;391(6664):240.
1997: S Ugolini; I Mondor; Paul W H I Parren; Dennis R Burton; S A Tilley; Per Johan Klasse; Quentin J Sattentau
Inhibition of virus attachment to CD4+ target cells is a major mechanism of T cell line-adapted HIV-1 neutralization.
The Journal of experimental medicine 1997;186(8):1287-98.
1997: S Ugolini; Maxime Moulard; I Mondor; N Barois; D Demandolx; James A Hoxie; Anne Brelot; Marc Alizon; Jean Davoust; Quentin J Sattentau
HIV-1 gp120 induces an association between CD4 and the chemokine receptor CXCR4.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):3000-8.
1997: Paul W H I Parren; Marie-Claire E Gauduin; RA Koup; Pascal Poignard; Quentin J Sattentau; P Fisicaro; Dennis R Burton
Erratum to "Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design".
Immunology letters 1997;58(2):125-32.
1997: Paul W H I Parren; Marie-Claire E Gauduin; RA Koup; Pascal Poignard; P Fisicaro; Dennis R Burton; Quentin J Sattentau
Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design.
Immunology letters 1997;57(1-3):105-12.
1997: P Gluschankof; I Mondor; H R Gelderblom; Quentin J Sattentau
Cell membrane vesicles are a major contaminant of gradient-enriched human immunodeficiency virus type-1 preparations.
Virology 1997;230(1):125-33.
1997: Galina Denisova; D Raviv; I Mondor; Quentin J Sattentau; Jonathan M Gershoni
Conformational transitions in CD4 due to complexation with HIV envelope glycoprotein gp120.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1157-64.
1997: J H Simon; Philip A Stumbles; N Signoret; C Somoza; Michael J Puklavec; Quentin J Sattentau; A Neil Barclay; William James
Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1.
Journal of virology 1997;71(2):1476-84.
1997: N Signoret; J de Jong; J Goudsmit; Quentin J Sattentau
Mutations within the CD4-CDR-3-like loop allow replication in an immortalized T cell line of HIV type 1 viruses chimeric for envelope glycoproteins containing non-syncytium-inducing V3 loops.
AIDS research and human retroviruses 1997;13(2):121-3.
1996: Quentin J Sattentau
Neutralization of HIV-1 by antibody.
Current opinion in immunology 1996;8(4):540-5.
1996: Per Johan Klasse; Quentin J Sattentau
Altered CD4 interactions of HIV type 1 LAI variants selected for the capacity to induce membrane fusion in the presence of a monoclonal antibody to domain 2 of CD4.
AIDS research and human retroviruses 1996;12(11):1015-21.
1996: N Signoret; D Blanc-Zouaoui; P D Kwong; Quentin J Sattentau
Selective effects of electrostatic changes in the CD4 CDR-3-like loop on infection by different human immunodeficiency virus type 1 isolates.
AIDS research and human retroviruses 1996;12(11):1001-13.
1996: Pascal Poignard; Per Johan Klasse; Quentin J Sattentau
Antibody neutralization of HIV-1.
Immunology today 1996;17(5):239-46.
1996: Pascal Poignard; T Fouts; Denise Naniche; J P Moore; Quentin J Sattentau
Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation.
The Journal of experimental medicine 1996;183(2):473-84.
1995: Quentin J Sattentau; Susan Zolla-Pazner; Pascal Poignard
Epitope exposure on functional, oligomeric HIV-1 gp41 molecules.
Virology 1995;206(1):713-7.
1995: J P Moore; Y Cao; L Qing; Quentin J Sattentau; J Pyati; R Koduri; J Robinson; Carlos F Barbas; Dennis R Burton; David D Ho
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
Journal of virology 1995;69(1):101-9.
1994: I Lazaro; D Naniche; N Signoret; A M Bernard; D Marguet; D Klatzmann; T Dragic; Marc Alizon; Quentin J Sattentau
Factors involved in entry of the human immunodeficiency virus type 1 into permissive cells: lack of evidence of a role for CD26.
Journal of virology 1994;68(10):6535-46.
1994: J P Moore; Quentin J Sattentau; Richard Wyatt; Joseph Sodroski
Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies.
Journal of virology 1994;68(1):469-84.
1993: N Signoret; Pascal Poignard; D Blanc; Quentin J Sattentau
Human and simian immunodeficiency viruses: virus-receptor interactions.
Trends in microbiology 1993;1(9):328-33.
1993: Quentin J Sattentau; J P Moore; F Vignaux; F Traincard; Pascal Poignard
Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding.
Journal of virology 1993;67(12):7383-93.
1993: J P Moore; B A Jameson; Quentin J Sattentau; R Willey; Joseph Sodroski
Towards a structure of the HIV-1 envelope glycoprotein gp120: an immunochemical approach.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;342(1299):83-8.
1993: Quentin J Sattentau; J P Moore
The role of CD4 in HIV binding and entry.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;342(1299):59-66.
1993: J P Moore; Quentin J Sattentau; H Yoshiyama; M Thali; M Charles; N Sullivan; S W Poon; M S Fung; F Traincard; M Pinkus
Probing the structure of the V2 domain of human immunodeficiency virus type 1 surface glycoprotein gp120 with a panel of eight monoclonal antibodies: human immune response to the V1 and V2 domains.
Journal of virology 1993;67(10):6136-51.
1992: Quentin J Sattentau
CD4 activation of HIV fusion.
International journal of cell cloning 1992;10(6):323-32.
1992: J P Moore; Quentin J Sattentau; Per Johan Klasse; L C Burkly
A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells.
Journal of virology 1992;66(8):4784-93.
1991: Quentin J Sattentau; J P Moore
Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding.
The Journal of experimental medicine 1991;174(2):407-15.
1991: D G Healey; L Dianda; D Buck; K Schroeder; A Truneh; Quentin J Sattentau; Peter C L Beverley
A highly selected panel of anti-CD4 antibodies fails to induce anti-idiotypic antisera mediating human immunodeficiency virus neutralization.
European journal of immunology 1991;21(6):1491-8.
1991: Alemseged Truneh; D Buck; David R Cassatt; R Juszczak; S Kassis; S E Ryu; D Healey; R Sweet; Quentin J Sattentau
A region in domain 1 of CD4 distinct from the primary gp120 binding site is involved in HIV infection and virus-mediated fusion.
The Journal of biological chemistry 1991;266(9):5942-8.
1991: J P Moore; Jane A McKeating; W A Norton; Quentin J Sattentau
Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4.
Journal of virology 1991;65(3):1133-40.
1990: J P Moore; Jane A McKeating; Robin A Weiss; Quentin J Sattentau
Dissociation of gp120 from HIV-1 virions induced by soluble CD4.
Science (New York, N.Y.) 1990;250(4984):1139-42.
1990: J P Moore; Quentin J Sattentau; Paul R Clapham
Enhancement of soluble CD4-mediated HIV neutralization and gp 120 binding by CD4 autoantibodies and monoclonal antibodies.
AIDS research and human retroviruses 1990;6(11):1273-9.
1990: M Merkenschlager; D Buck; Peter C L Beverley; Quentin J Sattentau
Functional epitope analysis of the human CD4 molecule. The MHC class II-dependent activation of resting T cells is inhibited by monoclonal antibodies to CD4 regardless whether or not they recognize epitopes involved in the binding of MHC class II or HIV gp120.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):2839-45.
1990: D Healey; L Dianda; J P Moore; J S McDougal; M J Moore; P Estess; D Buck; P D Kwong; Peter C L Beverley; Quentin J Sattentau
Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding.
The Journal of experimental medicine 1990;172(4):1233-42.
1989: Quentin J Sattentau
HIV infection and the immune system.
Biochimica et biophysica acta 1989;989(3):255-68.
1989: Quentin J Sattentau; J Arthos; K Deen; N Hanna; D Healey; Peter C L Beverley; R Sweet; Alemseged Truneh
Structural analysis of the human immunodeficiency virus-binding domain of CD4. Epitope mapping with site-directed mutants and anti-idiotypes.
The Journal of experimental medicine 1989;170(4):1319-34.
1989: Peter C L Beverley; D Healey; K Broadhurst; Quentin J Sattentau
Limitations of the anti-idiotype strategy for an HIV vaccine.
Journal of autoimmunity 1989;2 Suppl():243-9.
1989: J Arthos; K C Deen; M A Chaikin; J A Fornwald; G Sathe; Quentin J Sattentau; Paul R Clapham; Robin A Weiss; J S McDougal; C Pietropaolo
Identification of the residues in human CD4 critical for the binding of HIV.
Cell 1989;57(3):469-81.
1988: Quentin J Sattentau; P R Clapham; Robin A Weiss; Peter C L Beverley; Luc Montagnier; M F Alhalabi; J C Gluckmann; D Klatzmann
The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule.
AIDS (London, England) 1988;2(2):101-5.
1988: Quentin J Sattentau; Robin A Weiss
The CD4 antigen: physiological ligand and HIV receptor.
Cell 1988;52(5):631-3.
1988: Quentin J Sattentau
The role of the CD4 antigen in HIV infection and immune pathogenesis.
AIDS (London, England) 1988;2 Suppl 1():S11-6.
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