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Ann Saunders

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Akuffo Emma L; Davis John B; Fox Steven M; Gloger Israel S; Hosford David; Kinsey Emma E; Jones Neil A; Nock Christina M; Roses Allen D; Saunders Ann M; Skehel J Mark; Smith Marjorie A; Cutler Paul
The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone.
Cogswell John P; Ward James; Taylor Ian A; Waters Michelle; Shi Yunling; Cannon Brian; Kelnar Kevin; Kemppainen Jon; Brown David; Chen Caifu; Prinjha Rab K; Richardson Jill C; Saunders Ann M; Roses Allen D; Richards Cynthia A
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways.
Brodbeck Jens; Balestra Maureen E; Saunders Ann M; Roses Allen D; Mahley Robert W; Huang Yadong
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons.

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All Publications

2008: Akuffo Emma L; Davis John B; Fox Steven M; Gloger Israel S; Hosford David; Kinsey Emma E; Jones Neil A; Nock Christina M; Roses Allen D; Saunders Ann M; Skehel J Mark; Smith Marjorie A; Cutler Paul
The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008;13(6):618-36.
2008: Cogswell John P; Ward James; Taylor Ian A; Waters Michelle; Shi Yunling; Cannon Brian; Kelnar Kevin; Kemppainen Jon; Brown David; Chen Caifu; Prinjha Rab K; Richardson Jill C; Saunders Ann M; Roses Allen D; Richards Cynthia A
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways.
Journal of Alzheimer's disease : JAD 2008;14(1):27-41.
2008: Brodbeck Jens; Balestra Maureen E; Saunders Ann M; Roses Allen D; Mahley Robert W; Huang Yadong
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1343-6.
2008: Li Hao; Wetten Sally; Li Li; St Jean Pamela L; Upmanyu Ruchi; Surh Linda; Hosford David; Barnes Michael R; Briley James David; Borrie Michael; Coletta Natalie; Delisle Richard; Dhalla Daniella; Ehm Margaret G; Feldman Howard H; Fornazzari Luis; Gauthier Serge; Goodgame Neil; Guzman Danilo; Hammond Sandra; Hollingworth Paul; Hsiung Ging-Yuek; Johnson Joan; Kelly Devon D; Keren Ron; Kertesz Andrew; King Karen S; Lovestone Simon; Loy-English Inge; Matthews Paul M; Owen Michael J; Plumpton Mary; Pryse-Phillips William; Prinjha Rab K; Richardson Jill C; Saunders Ann; Slater Andrew J; St George-Hyslop Peter H; Stinnett Sandra W; Swartz Jina E; Taylor Rachel L; Wherrett John; Williams Julie; Yarnall David P; Gibson Rachel A; Irizarry Michael C; Middleton Lefkos T; Roses Allen D
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Archives of neurology 2008;65(1):45-53.
2007: Chen Kewei; Reiman Eric M; Alexander Gene E; Caselli Richard J; Gerkin Richard; Bandy Daniel; Domb Alisa; Osborne David; Fox Nick; Crum William R; Saunders Ann M; Hardy John
Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates.
The American journal of psychiatry 2007;164(6):916-21.
2007: Strum Jay C; Shehee Ron; Virley David; Richardson Jill; Mattie Michael; Selley Paula; Ghosh Sujoy; Nock Christina; Saunders Ann; Roses Allen
Rosiglitazone induces mitochondrial biogenesis in mouse brain.
Journal of Alzheimer's disease : JAD 2007;11(1):45-51.
2007: Roses A D; Saunders A M; Huang Y; Strum J; Weisgraber K H; Mahley R W
Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).
The pharmacogenomics journal 2007;7(1):10-28.
2006: Risner M E; Saunders A M; Altman J F B; Ormandy G C; Craft S; Foley I M; Zvartau-Hind M E; Hosford D A; Roses A D;
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease.
The pharmacogenomics journal 2006;6(4):246-54.
2006: Halford Jonathan; Mazeika Gandis; Slifer Susan; Speer Marcy; Saunders Ann M; Strittmatter Warren J; Morgenlander Joel C
APOE2 allele increased in tardive dyskinesia.
Movement disorders : official journal of the Movement Disorder Society 2006;21(4):540-2.
2005: Reiman Eric M; Chen Kewei; Alexander Gene E; Caselli Richard J; Bandy Daniel; Osborne David; Saunders Ann M; Hardy John
Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8299-302.
2005: Ahmadi Kourosh R; Weale Mike E; Xue Zhengyu Y; Soranzo Nicole; Yarnall David P; Briley James D; Maruyama Yuka; Kobayashi Mikiro; Wood Nicholas W; Spurr Nigel K; Burns Daniel K; Roses Allen D; Saunders Ann M; Goldstein David B
A single-nucleotide polymorphism tagging set for human drug metabolism and transport.
Nature genetics 2005;37(1):84-9.
2005: Liu Chang; Ghosh Sujoy; Searls David B; Saunders Ann M; Cossman Jeffrey; Roses Allen D
Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery.
Omics : a journal of integrative biology 2005;9(4):351-63.
2004: Li Yi-Ju; Pericak-Vance Margaret A; Haines Jonathan L; Siddique Nailah; McKenna-Yasek Diane; Hung Wu-Yen; Sapp Peter; Allen Coy I; Chen Wenjie; Hosler Betsy; Saunders Ann M; Dellefave Lisa M; Brown Robert H; Siddique Teepu
Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis.
Neurogenetics 2004;5(4):209-13.
2004: Nicodemus Kristin K; Stenger Judith E; Schmechel Donald E; Welsh-Bohmer Kathleen A; Saunders Ann M; Roses Allen D; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A; Martin Eden R
Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.
Neurogenetics 2004;5(4):201-8.
2004: van der Walt Joelle M; Dementieva Yulia A; Martin Eden R; Scott William K; Nicodemus Kristin K; Kroner Charles C; Welsh-Bohmer Kathleen A; Saunders Ann M; Roses Allen D; Small Gary W; Schmechel Donald E; Murali Doraiswamy P; Gilbert John R; Haines Jonathan L; Vance Jeffery M; Pericak-Vance Margaret A
Analysis of European mitochondrial haplogroups with Alzheimer disease risk.
Neuroscience letters 2004;365(1):28-32.
2004: Galli Kristin K; Zimmerman Robert A; Jarvik Gail P; Wernovsky Gil; Kuypers Marijn K; Clancy Robert R; Montenegro Lisa M; Mahle William T; Newman Mark F; Saunders Ann M; Nicolson Susan C; Spray Thomas L; Gaynor J William;
Periventricular leukomalacia is common after neonatal cardiac surgery.
The Journal of thoracic and cardiovascular surgery 2004;127(3):692-704.
2004: Reiman Eric M; Chen Kewei; Alexander Gene E; Caselli Richard J; Bandy Daniel; Osborne David; Saunders Ann M; Hardy John
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):284-9.
2004: Danoff T M; Campbell D A; McCarthy L C; Lewis K F; Repasch M H; Saunders A M; Spurr N K; Purvis I J; Roses A D; Xu C-F
A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia.
The pharmacogenomics journal 2004;4(1):49-53.
2003: Gaynor J William; Gerdes Marsha; Zackai Elaine H; Bernbaum Judy; Wernovsky Gil; Clancy Robert R; Newman Mark F; Saunders Ann M; Heagerty Patrick J; D'Agostino Jo Ann; McDonald-McGinn Donna; Nicolson Susan C; Spray Thomas L; Jarvik Gail P
Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery.
The Journal of thoracic and cardiovascular surgery 2003;126(6):1736-45.
2003: Li Yi-Ju; Oliveira Sofia A; Xu Puting; Martin Eden R; Stenger Judith E; Scherzer Clemens R; Hauser Michael A; Scott William K; Small Gary W; Nance Martha A; Watts Ray L; Hubble Jean P; Koller William C; Pahwa Rajesh; Stern Mathew B; Hiner Bradley C; Jankovic Joseph; Goetz Christopher G; Mastaglia Frank; Middleton Lefkos T; Roses Allen D; Saunders Ann M; Schmechel Donald E; Gullans Steven R; Haines Jonathan L; Gilbert John R; Vance Jeffery M; Pericak-Vance Margaret A; Hulette Christine; Welsh-Bohmer Kathleen A
Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.
Human molecular genetics 2003;12(24):3259-67.
2003: Scott William K; Hauser Elizabeth R; Schmechel Donald E; Welsh-Bohmer Kathleen A; Small Gary W; Roses Allen D; Saunders Ann M; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A
Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.
American journal of human genetics 2003;73(5):1041-51.
2003: Oliveira Sofia A; Martin Eden R; Scott William K; Nicodemus Kristin K; Small Gary W; Schmechel Donald E; Doraiswamy P Murali; Roses Allen D; Saunders Ann M; Gilbert John R; Haines Jonathan L; Vance Jeffery M; Pericak-Vance Margaret A
The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.
Neuroscience letters 2003;347(3):143-6.
2003: DeKroon Robert M; Mihovilovic Mirta; Goodger Zoe V; Robinette Jennifer B; Sullivan Patrick M; Saunders Ann M; Strittmatter Warren J
ApoE genotype-specific inhibition of apoptosis.
Journal of lipid research 2003;44(8):1566-73.
2003: Bedlack R S; Edelman D; Gibbs J W; Kelling D; Strittmatter W; Saunders A M; Morgenlander J
APOE genotype is a risk factor for neuropathy severity in diabetic patients.
Neurology 2003;60(6):1022-4.
2002: Schmidt Silke; Klaver Caroline; Saunders Ann; Postel Eric; De La Paz Monica; Agarwal Anita; Small Kent; Udar Nitin; Ong John; Chalukya Meenal; Nesburn Anthony; Kenney Cristina; Domurath Ruth; Hogan Molly; Mah Tammy; Conley Yvette; Ferrell Robert; Weeks Daniel; de Jong Paulus T V M; van Duijn Cornelia; Haines Jonathan; Pericak-Vance Margaret; Gorin Michael
A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy.
Ophthalmic genetics 2002;23(4):209-23.
2002: Colton Carol A; Brown Candice M; Cook Danielle; Needham Leila K; Xu Qing; Czapiga Meggan; Saunders Ann M; Schmechel Donald E; Rasheed Karima; Vitek Michael P
APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.
Neurobiology of aging 2002;23(5):777-85.
2002: Fillenbaum Gerda G; Blazer Dan G; Burchett Bruce M; Saunders Ann M; Taylor Donald H
Apolipoprotein E epsilon4 and risk of mortality in African American and white older community residents.
The Gerontologist 2002;42(3):381-6.
2002: Li Yi-Ju; Scott William K; Hedges Dale J; Zhang Fengyu; Gaskell P Craig; Nance Martha A; Watts Ray L; Hubble Jean P; Koller William C; Pahwa Rajesh; Stern Matthew B; Hiner Bradley C; Jankovic Joseph; Allen Fred A; Goetz Christopher G; Mastaglia Frank; Stajich Jeffrey M; Gibson Rachel A; Middleton Lefkos T; Saunders Ann M; Scott Burton L; Small Gary W; Nicodemus Kristin K; Reed Allison D; Schmechel Donald E; Welsh-Bohmer Kathleen A; Conneally P Michael; Roses Allen D; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A
Age at onset in two common neurodegenerative diseases is genetically controlled.
American journal of human genetics 2002;70(4):985-93.
2002: Schmidt Silke; Barcellos Lisa F; DeSombre Karen; Rimmler Jacqueline B; Lincoln Robin R; Bucher Patricia; Saunders Ann M; Lai Eric; Martin Eden R; Vance Jeffery M; Oksenberg Jorge R; Hauser Stephen L; Pericak-Vance Margaret A; Haines Jonathan L;
Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis.
American journal of human genetics 2002;70(3):708-17.
2002: Caselli Richard J; Hentz Joseph G; Osborne David; Graff-Radford Neill R; Barbieri Carolyn J; Alexander Gene E; Hall Geri R; Reiman Eric M; Hardy John; Saunders Ann M
Apolipoprotein E and intellectual achievement.
Journal of the American Geriatrics Society 2002;50(1):49-54.
2001: Rosenberg C K; Cummings T J; Saunders A M; Widico C; McIntyre L M; Hulette C M
Dementia with Lewy bodies and Alzheimer's disease.
Acta neuropathologica 2001;102(6):621-6.
2001: Fillenbaum G G; Landerman L R; Blazer D G; Saunders A M; Harris T B; Launer L J
The relationship of APOE genotype to cognitive functioning in older African-American and Caucasian community residents.
Journal of the American Geriatrics Society 2001;49(9):1148-55.
2001: Caselli R J; Osborne D; Reiman E M; Hentz J G; Barbieri C J; Saunders A M; Hardy J; Graff-Radford N R; Hall G R; Alexander G E
Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study.
Journal of the neurological sciences 2001;189(1-2):93-8.
2001: Saunders A M
Gene identification in Alzheimer's disease.
Pharmacogenomics 2001;2(3):239-49.
2001: Newman M F; Laskowitz D T; White W D; Kirchner J L; Grocott H P; Stafford-Smith M; Sketch M H; Jones R H; Reves J G; Saunders A M
Apolipoprotein E polymorphisms and age at first coronary artery bypass graft.
Anesthesia and analgesia 2001;92(4):824-9.
2000: Schmidt S; Saunders A M; De La Paz MA; Postel E A; Heinis R M; Agarwal A; Scott W K; Gilbert J R; McDowell J G; Bazyk A; Gass J D; Haines J L; Pericak-Vance M A
Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender.
Molecular vision 2000;6():287-93.
2000: Pericak-Vance M A; Grubber J; Bailey L R; Hedges D; West S; Santoro L; Kemmerer B; Hall J L; Saunders A M; Roses A D; Small G W; Scott W K; Conneally P M; Vance J M; Haines J L
Identification of novel genes in late-onset Alzheimer's disease.
Experimental gerontology 2000;35(9-10):1343-52.
2000: Kardaun J W; White L; Resnick H E; Petrovitch H; Marcovina S M; Saunders A M; Foley D J; Havlik R J
Genotypes and phenotypes for apolipoprotein E and Alzheimer disease in the Honolulu-Asia aging study.
Clinical chemistry 2000;46(10):1548-54.
2000: Saunders A M
Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses.
Journal of neuropathology and experimental neurology 2000;59(9):751-8.
2000: Rosenberg C K; Pericak-Vance M A; Saunders A M; Gilbert J R; Gaskell P C; Hulette C M
Lewy body and Alzheimer pathology in a family with the amyloid-beta precursor protein APP717 gene mutation.
Acta neuropathologica 2000;100(2):145-52.
2000: Bookheimer S Y; Strojwas M H; Cohen M S; Saunders A M; Pericak-Vance M A; Mazziotta J C; Small G W
Patterns of brain activation in people at risk for Alzheimer's disease.
The New England journal of medicine 2000;343(7):450-6.
2000: Chew S T; Newman M F; White W D; Conlon P J; Saunders A M; Strittmatter W J; Landolfo K; Grocott H P; Stafford-Smith M
Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients.
Anesthesiology 2000;93(2):325-31.
2000: Saunders A M; Trowers M K; Shimkets R A; Blakemore S; Crowther D J; Mansfield T A; Wallace D M; Strittmatter W J; Roses A D
The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection.
Biochimica et biophysica acta 2000;1502(1):85-94.
2000: Small G W; Ercoli L M; Silverman D H; Huang S C; Komo S; Bookheimer S Y; Lavretsky H; Miller K; Siddarth P; Rasgon N L; Mazziotta J C; Saxena S; Wu H M; Mega M S; Cummings J L; Saunders A M; Pericak-Vance M A; Roses A D; Barrio J R; Phelps M E
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6037-42.
2000: Havlik R J; Izmirlian G; Petrovitch H; Ross G W; Masaki K; Curb J D; Saunders A M; Foley D J; Brock D; Launer L J; White L
APOE-epsilon4 predicts incident AD in Japanese-American men: the honolulu-asia aging study.
Neurology 2000;54(7):1526-9.
2000: Riley K P; Snowdon D A; Saunders A M; Roses A D; Mortimer J A; Nanayakkara N
Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study.
The journals of gerontology. Series B, Psychological sciences and social sciences 2000;55(2):S69-75.
2000: Scott W K; Grubber J M; Conneally P M; Small G W; Hulette C M; Rosenberg C K; Saunders A M; Roses A D; Haines J L; Pericak-Vance M A
Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity.
American journal of human genetics 2000;66(3):922-32.
2000: Martin E R; Gilbert J R; Lai E H; Riley J; Rogala A R; Slotterbeck B D; Sipe C A; Grubber J M; Warren L L; Conneally P M; Saunders A M; Schmechel D E; Purvis I; Pericak-Vance M A; Roses A D; Vance J M
Analysis of association at single nucleotide polymorphisms in the APOE region.
Genomics 2000;63(1):7-12.
1999: McCarron M O; Hoffmann K L; DeLong D M; Gray L; Saunders A M; Alberts M J
Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes.
Neurology 1999;53(9):2176-9.
1999: Small G W; Scott W K; Komo S; Yamaoka L H; Farrer L A; Auerbach S H; Saunders A M; Roses A D; Haines J L; Pericak-Vance M A
No association between the HLA-A2 allele and Alzheimer disease.
Neurogenetics 1999;2(3):177-82.
1999: Grubber J M; Saunders A M; Crane-Gatherum A R; Scott W K; Martin E R; Haynes C S; Conneally P M; Small G W; Roses A D; Haines J L; Pericak-Vance M A
Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K).
Neuroscience letters 1999;269(2):115-9.
1999: Small G W; Chen S T; Komo S; Ercoli L; Bookheimer S; Miller K; Lavretsky H; Saxena S; Kaplan A; Dorsey D; Scott W K; Saunders A M; Haines J L; Roses A D; Pericak-Vance M A
Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele.
The American journal of psychiatry 1999;156(7):1035-8.
1999: Rogaeva E A; Premkumar S; Grubber J; Serneels L; Scott W K; Kawarai T; Song Y; Hill D L; Abou-Donia S M; Martin E R; Vance J J; Yu G; Orlacchio A; Pei Y; Nishimura M; Supala A; Roberge B; Saunders A M; Roses A D; Schmechel D; Crane-Gatherum A; Sorbi S; Bruni A; Small G W; Conneally P M; Haines J L; Van Leuven F; St George-Hyslop P H; Farrer L A; Pericak-Vance M A
An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.
Nature genetics 1999;22(1):19-22.
1999: Fernandez T; Yan W L; Hamburger S; Rapoport J L; Saunders A M; Schapiro M; Ginns E I; Sidransky E
Apolipoprotein E alleles in childhood-onset schizophrenia.
American journal of medical genetics 1999;88(2):211-3.
1999: Scott W K; Grubber J M; Abou-Donia S M; Church T D; Saunders A M; Roses A D; Pericak-Vance M A; Conneally P M; Small G W; Haines J L
Further evidence linking late-onset Alzheimer disease with chromosome 12.
JAMA : the journal of the American Medical Association 1999;281(6):513-4.
1998: Einstein G; Patel V; Bautista P; Kenna M; Melone L; Fader R; Karson K; Mann S; Saunders A M; Hulette C; Mash D; Roses A D; Schmechel D E
Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology.
Journal of neuropathology and experimental neurology 1998;57(12):1190-201.
1998: Hulette C M; Welsh-Bohmer K A; Murray M G; Saunders A M; Mash D C; McIntyre L M
Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals.
Journal of neuropathology and experimental neurology 1998;57(12):1168-74.
1998: Farrer L A; Abraham C R; Haines J L; Rogaeva E A; Song Y; McGraw W T; Brindle N; Premkumar S; Scott W K; Yamaoka L H; Saunders A M; Roses A D; Auerbach S A; Sorbi S; Duara R; Pericak-Vance M A; St George-Hyslop P H
Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Annals of neurology 1998;44(5):808-11.
1998: Williams K R; Saunders A M; Roses A D; Armati P J
Uptake and internalization of exogenous apolipoprotein E3 by cultured human central nervous system neurons.
Neurobiology of disease 1998;5(4):271-9.
1998: Bass M P; Yamaoka L H; Scott W K; Gaskell P C; Welsh-Bohmer K A; Roses A D; Saunders A M; Haines J L; Pericak-Vance M A
No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients.
Neuroscience letters 1998;250(2):79-82.
1998: Litvan I; Saunders A M
Apolipoprotein E4 (epsilon) allele does not affect the onset or symptom severity in progressive supranuclear palsy.
Archives of neurology 1998;55(5):752-4.
1998: Tamaoka A; Fraser P E; Ishii K; Sahara N; Ozawa K; Ikeda M; Saunders A M; Komatsuzaki Y; Sherrington R; Levesque G; Yu G; Rogaeva E; Shoji S; Nee L E; Pollen D A; Hendriks L; Martin J J; Van Broeckhoven C; Roses A D; Farrer L A; St George-Hyslop P H; Mori H
Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.
Brain research. Molecular brain research 1998;56(1-2):178-85.
1998: Sheng H; Laskowitz D T; Bennett E; Schmechel D E; Bart R D; Saunders A M; Pearlstein R D; Roses A D; Warner D S
Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(4):361-6.
1998: Siddique T; Pericak-Vance M A; Caliendo J; Hong S T; Hung W Y; Kaplan J; McKenna-Yasek D; Rimmler J B; Sapp P; Saunders A M; Scott W K; Siddique N; Haines J L; Brown R H
Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis.
Neurogenetics 1998;1(3):213-6.
1998: Scott W K; Yamaoka L H; Bass M P; Gaskell P C; Conneally P M; Small G W; Farrer L A; Auerbach S A; Saunders A M; Roses A D; Haines J L; Pericak-Vance M A
No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.
Neurogenetics 1998;1(3):179-83.
1998: Breitner J C; Jarvik G P; Plassman B L; Saunders A M; Welsh K A
Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62-73 years.
Alzheimer disease and associated disorders 1998;12(1):40-4.
1998: Berg L; McKeel D W; Miller J P; Storandt M; Rubin E H; Morris J C; Baty J; Coats M; Norton J; Goate A M; Price J L; Gearing M; Mirra S S; Saunders A M
Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.
Archives of neurology 1998;55(3):326-35.
1998: Mayeux R; Saunders A M; Shea S; Mirra S; Evans D; Roses A D; Hyman B T; Crain B; Tang M X; Phelps C H
Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease.
The New England journal of medicine 1998;338(8):506-11.
1998: Roses A D; Gilbert J; Xu P T; Sullivan P; Popko B; Burkhart D S; Christian-Rothrock T; Saunders A M; Maeda N; Schmechel D E
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.
Neurobiology of aging 1998;19(1 Suppl):S53-8.
1998: Pericak-Vance M A; Bass M L; Yamaoka L H; Gaskell P C; Scott W K; Terwedow H A; Menold M M; Conneally P M; Small G W; Saunders A M; Roses A D; Haines J L
Complete genomic screen in late-onset familial Alzheimer's disease.
Neurobiology of aging 1998;19(1 Suppl):S39-42.
1997: Okochi M; Ishii K; Usami M; Sahara N; Kametani F; Tanaka K; Fraser P E; Ikeda M; Saunders A M; Hendriks L; Shoji S I; Nee L E; Martin J J; Van Broeckhoven C; St George-Hyslop P H; Roses A D; Mori H
Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
FEBS letters 1997;418(1-2):162-6.
1997: Pericak-Vance M A; Bass M P; Yamaoka L H; Gaskell P C; Scott W K; Terwedow H A; Menold M M; Conneally P M; Small G W; Vance J M; Saunders A M; Roses A D; Haines J L
Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.
JAMA : the journal of the American Medical Association 1997;278(15):1237-41.
1997: Roses A D; Saunders A M
ApoE, Alzheimer's disease, and recovery from brain stress.
Annals of the New York Academy of Sciences 1997;826():200-12.
1997: Tardiff B E; Newman M F; Saunders A M; Strittmatter W J; Blumenthal J A; White W D; Croughwell N D; Davis R D; Roses A D; Reves J G
Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
The Annals of thoracic surgery 1997;64(3):715-20.
1997: Scott W K; Saunders A M; Gaskell P C; Locke P A; Growdon J H; Farrer L A; Auerbach S A; Roses A D; Haines J L; Pericak-Vance M A
Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease.
Annals of neurology 1997;42(3):376-8.
1997: Welsh-Bohmer K A; Gearing M; Saunders A M; Roses A D; Mirra S
Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease.
Annals of neurology 1997;42(3):319-25.
1997: Roses A D; Saunders A M
Clinical overdiagnosis of vascular dementia versus necropsy confirmed series.
Journal of neurology, neurosurgery, and psychiatry 1997;62(6):677-8.
1997: Alexander G E; Saunders A M; Szczepanik J; Strassburger T L; Pietrini P; Dani A; Furey M L; Mentis M J; Roses A D; Rapoport S I; Schapiro M B
Relation of age and apolipoprotein E to cognitive function in Down syndrome adults.
Neuroreport 1997;8(8):1835-40.
1997: Plassman B L; Welsh-Bohmer K A; Bigler E D; Johnson S C; Anderson C V; Helms M J; Saunders A M; Breitner J C
Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition.
Neurology 1997;48(4):985-9.
1997: Steffens D C; Plassman B L; Helms M J; Welsh-Bohmer K A; Saunders A M; Breitner J C
A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease.
Biological psychiatry 1997;41(8):851-6.
1997: Small G W; Noble E P; Matsuyama S S; Jarvik L F; Komo S; Kaplan A; Ritchie T; Pritchard M L; Saunders A M; Conneally P M; Roses A D; Haines J L; Pericak-Vance M A
D2 dopamine receptor A1 allele in Alzheimer disease and aging.
Archives of neurology 1997;54(3):281-5.
1997: Roses A D; Saunders A M
Prediction for unimpaired subjects is different from diagnosis of demented patients.
Annals of neurology 1997;41(3):414-6.
1997: Lippa C F; Smith T W; Saunders A M; Hulette C; Pulaski-Salo D; Roses A D
Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype.
Neurology 1997;48(2):515-9.
1997: Roses A D; Saunders A M
Apolipoprotein E genotyping as a diagnostic adjunct for Alzheimer's disease.
International psychogeriatrics / IPA 1997;9 Suppl 1():277-88; discussion 317-21.
1997: Williams K R; Pye V; Saunders A M; Roses A D; Armati P J
Apolipoprotein E uptake and low-density lipoprotein receptor-related protein expression by the NTera2/D1 cell line: a cell culture model of relevance for late-onset Alzheimer's disease.
Neurobiology of disease 1997;4(1):58-67.
1997: Scott W K; Yamaoka L H; Locke P A; Rosi B L; Gaskell P C; Saunders A M; Conneally P M; Small G W; Farrer L A; Growdon J H; Roses A D; Pericak-Vance M A; Haines J L
No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease.
Genetic epidemiology 1997;14(3):307-15.
1996: Small G W; Komo S; La Rue A; Saxena S; Phelps M E; Mazziotta J C; Saunders A M; Haines J L; Pericak-Vance M A; Roses A D
Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging.
Annals of the New York Academy of Sciences 1996;802():70-8.
1996: Haines J L; Pritchard M L; Saunders A M; Schildkraut J M; Growdon J H; Gaskell P C; Farrer L A; Auerbach S A; Gusella J F; Locke P A; Rosi B L; Yamaoka L; Small G W; Conneally P M; Roses A D; Pericak-Vance M
No association between alpha 1-antichymotrypsin and familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;802():35-41.
1996: Roses A D; Saunders A M
Evaluation of suspected dementia.
The New England journal of medicine 1996;335(26):1996; author reply 1997-8.
1996: Askanas V; Engel W K; Mirabella M; Weisgraber K H; Saunders A M; Roses A D; McFerrin J
Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy.
Annals of neurology 1996;40(2):264-5.
1996: Okuizumi K; Onodera O; Seki K; Tanaka H; Namba Y; Ikeda K; Saunders A M; Pericak-Vance M A; Roses A D; Tsuji S
Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease.
Annals of neurology 1996;40(2):251-4.
1996: Saunders A M; Hulette O; Welsh-Bohmer K A; Schmechel D E; Crain B; Burke J R; Alberts M J; Strittmatter W J; Breitner J C; Rosenberg C
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.
Lancet 1996;348(9020):90-3.
1996: Pericak-Vance M A; Johnson C C; Rimmler J B; Saunders A M; Robinson L C; D'Hondt E G; Jackson C E; Haines J L
Alzheimer's disease and apolipoprotein E-4 allele in an Amish population.
Annals of neurology 1996;39(6):700-4.
1996: Pritchard M L; Saunders A M; Gaskell P C; Small G W; Conneally P M; Rosi B; Yamaoka L H; Roses A D; Haines J L; Pericak-Vance M A
No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians.
Neuroscience letters 1996;209(2):105-8.
1996: Haines J L; Pritchard M L; Saunders A M; Schildkraut J M; Growdon J H; Gaskell P C; Farrer L A; Auerbach S A; Gusella J F; Locke P A; Rosi B L; Yamaoka L; Small G W; Conneally P M; Roses A D; Pericak-Vance M A
No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.
Genomics 1996;33(1):53-6.
1996: Montine T J; Huang D Y; Valentine W M; Amarnath V; Saunders A; Weisgraber K H; Graham D G; Strittmatter W J
Crosslinking of apolipoprotein E by products of lipid peroxidation.
Journal of neuropathology and experimental neurology 1996;55(2):202-10.
1996: Lippa C F; Saunders A M; Smith T W; Swearer J M; Drachman D A; Ghetti B; Nee L; Pulaski-Salo D; Dickson D; Robitaille Y; Bergeron C; Crain B; Benson M D; Farlow M; Hyman B T; George-Hyslop S P; Roses A D; Pollen D A
Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway.
Neurology 1996;46(2):406-12.
1996: Roses A D; Einstein G; Gilbert J; Goedert M; Han S H; Huang D; Hulette C; Masliah E; Pericak-Vance M A; Saunders A M; Schmechel D E; Strittmatter W J; Weisgraber K H; Xi P T
Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism.
Annals of the New York Academy of Sciences 1996;777():146-57.
1996: Strittmatter W J; Burke J R; DeSerrano V S; Huang D Y; Matthew W; Saunders A M; Scott B L; Vance J M; Weisgraber K H; Roses A D
Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases.
Cold Spring Harbor symposia on quantitative biology 1996;61():597-605.
1996: Xu P T; Schmechel D; Rothrock-Christian T; Burkhart D S; Qiu H L; Popko B; Sullivan P; Maeda N; Saunders A M; Roses A D; Gilbert J R
Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.
Neurobiology of disease 1996;3(3):229-45.
1995: Alberts M J; Graffagnino C; McClenny C; DeLong D; Strittmatter W; Saunders A M; Roses A D
ApoE genotype and survival from intracerebral haemorrhage.
Lancet 1995;346(8974):575.
1995: Breitner J C; Welsh K A; Gau B A; McDonald W M; Steffens D C; Saunders A M; Magruder K M; Helms M J; Plassman B L; Folstein M F
Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance.
Archives of neurology 1995;52(8):763-71.
1995: Breitner J C; Welsh K A; Helms M J; Gaskell P C; Gau B A; Roses A D; Pericak-Vance M A; Saunders A M
Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.
Neurobiology of aging 1995;16(4):523-30.
1995: Corder E H; Saunders A M; Pericak-Vance M A; Roses A D
There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease.
Archives of neurology 1995;52(7):650-1.
1995: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Rimmler J B; Locke P A; Conneally P M; Schmader K E; Tanzi R E
Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease.
Neurology 1995;45(7):1323-8.
1995: Roses A D; Saunders A
Head injury, amyloid beta and Alzheimer's disease.
Nature medicine 1995;1(7):603-4.
1995: Huang D Y; Weisgraber K H; Goedert M; Saunders A M; Roses A D; Strittmatter W J
ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation.
Neuroscience letters 1995;192(3):209-12.
1995: Roses A D; Saunders A M; Corder E H; Pericak-Vance M A; Han S H; Einstein G; Hulette C; Schmechel D E; Holsti M; Huang D
Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):413-7.
1995: Roses A D; Saunders A M; Alberts M A; Strittmatter W J; Schmechel D; Gorder E; Pericak-Vance M A
Apolipoprotein E E4 allele and risk of dementia.
JAMA : the journal of the American Medical Association 1995;273(5):374-5; author reply 375-6.
1995: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Roses A D; Pericak-Vance M A; Small G W; Haines J L
The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease.
JAMA : the journal of the American Medical Association 1995;273(5):373-4.
1995: Plassman B L; Helms M J; Welsh K A; Saunders A M; Breitner J C
Smoking, Alzheimer's disease, and confounding with genes.
Lancet 1995;345(8946):387.
1995: Lippa C F; Smith T W; Saunders A M; Crook R; Pulaski-Salo D; Davies P; Hardy J; Roses A D; Dickson D
Apolipoprotein E genotype and Lewy body disease.
Neurology 1995;45(1):97-103.
1995: Roses A D; Saunders A M; Strittmatter W J; Schmechel D E; Pericak-Vance M A; Hyman B
Apolipoprotein E in Creutzfeldt-Jacob disease.
Lancet 1995;345(8941):69.
1994: Roses A D; Saunders A M
APOE is a major susceptibility gene for Alzheimer's disease.
Current opinion in biotechnology 1994;5(6):663-7.
1994: Strittmatter W J; Saunders A M; Goedert M; Weisgraber K H; Dong L M; Jakes R; Huang D Y; Pericak-Vance M; Schmechel D; Roses A D
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11183-6.
1994: Huang D Y; Goedert M; Jakes R; Weisgraber K H; Garner C C; Saunders A M; Pericak-Vance M A; Schmechel D E; Roses A D; Strittmatter W J
Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.
Neuroscience letters 1994;182(1):55-8.
1994: Han S H; Einstein G; Weisgraber K H; Strittmatter W J; Saunders A M; Pericak-Vance M; Roses A D; Schmechel D E
Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study.
Journal of neuropathology and experimental neurology 1994;53(5):535-44.
1994: Sanan D A; Weisgraber K H; Russell S J; Mahley R W; Huang D; Saunders A; Schmechel D; Wisniewski T; Frangione B; Roses A D
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
The Journal of clinical investigation 1994;94(2):860-9.
1994: Han S H; Hulette C; Saunders A M; Einstein G; Pericak-Vance M; Strittmatter W J; Roses A D; Schmechel D E
Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.
Experimental neurology 1994;128(1):13-26.
1994: Corder E H; Saunders A M; Risch N J; Strittmatter W J; Schmechel D E; Gaskell P C; Rimmler J B; Locke P A; Conneally P M; Schmader K E
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.
Nature genetics 1994;7(2):180-4.
1994: Roses A D; Strittmatter W J; Pericak-Vance M A; Corder E H; Saunders A M; Schmechel D E
Clinical application of apolipoprotein E genotyping to Alzheimer's disease.
Lancet 1994;343(8912):1564-5.
1994: Strittmatter W J; Weisgraber K H; Goedert M; Saunders A M; Huang D; Corder E H; Dong L M; Jakes R; Alberts M J; Gilbert J R
Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype.
Experimental neurology 1994;125(2):163-71; discussion 172-4.
1994: Roses A D; Pericak-Vance M A; Saunders A M; Schmechel D; Goldgaber D; Strittmatter W
Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy?
Epilepsia 1994;35 Suppl 1():S20-8.
1993: Schmechel D E; Saunders A M; Strittmatter W J; Crain B J; Hulette C M; Joo S H; Pericak-Vance M A; Goldgaber D; Roses A D
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9649-53.
1993: Strittmatter W J; Weisgraber K H; Huang D Y; Dong L M; Salvesen G S; Pericak-Vance M; Schmechel D; Saunders A M; Goldgaber D; Roses A D
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8098-102.
1993: Goldgaber D; Schwarzman A I; Bhasin R; Gregori L; Schmechel D; Saunders A M; Roses A D; Strittmatter W J
Sequestration of amyloid beta-peptide.
Annals of the New York Academy of Sciences 1993;695():139-43.
1993: Saunders A M; Roses A D
Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease.
Stroke; a journal of cerebral circulation 1993;24(9):1416-7.
1993: Saunders A M; Schmader K; Breitner J C; Benson M D; Brown W T; Goldfarb L; Goldgaber D; Manwaring M G; Szymanski M H; McCown N
Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.
Lancet 1993;342(8873):710-1.
1993: Saunders A M; Strittmatter W J; Schmechel D; George-Hyslop P H; Pericak-Vance M A; Joo S H; Rosi B L; Gusella J F; Crapper-MacLachlan D R; Alberts M J
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
Neurology 1993;43(8):1467-72.
1993: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Small G W; Roses A D; Haines J L; Pericak-Vance M A
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
Science (New York, N.Y.) 1993;261(5123):921-3.
1993: Strittmatter W J; Saunders A M; Schmechel D; Pericak-Vance M; Enghild J; Salvesen G S; Roses A D
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1977-81.
1992: Pröschel M; Saunders A; Roses A D; Müller C R
Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF).
Human molecular genetics 1992;1(5):353.
1991: Howard T A; Rochelle J M; Saunders A M; Seldin M F
A linkage map of mouse chromosome 8: further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19.
Genomics 1991;10(1):207-13.
1991: Seldin M F; Saunders A M; Rochelle J M; Howard T A
A proximal mouse chromosome 9 linkage map that further defines linkage groups homologous with segments of human chromosomes 11, 15, and 19.
Genomics 1991;9(4):678-85.
1990: Saunders A M; Seldin M F
A molecular genetic linkage map of mouse chromosome 7.
Genomics 1990;8(3):525-35.
1990: Saunders A M; Seldin M F
The syntenic relationship of proximal mouse chromosome 7 and the myotonic dystrophy gene region on human chromosome 19q.
Genomics 1990;6(2):324-32.

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