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Anders Björklund

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TOP 3
Mickael Decressac; Johan Jakobsson; Martin Lundblad; Bengt Mattsson; Pia Weikop; Anders Björklund
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Olof Torper; Daniel A Wolf; Maria Pereira; Ulrich Pfisterer; Anders Björklund; Shane Grealish; Johan Jakobsson; Shong Lau; Malin Parmar
Generation of induced neurons via direct conversion in vivo.
Anders Björklund; Jeffrey H Kordower
Cell therapy for Parkinson's disease: what next?

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All Publications

2013: Mickael Decressac; Johan Jakobsson; Martin Lundblad; Bengt Mattsson; Pia Weikop; Anders Björklund
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(19):E1817-26.
2013: Olof Torper; Daniel A Wolf; Maria Pereira; Ulrich Pfisterer; Anders Björklund; Shane Grealish; Johan Jakobsson; Shong Lau; Malin Parmar
Generation of induced neurons via direct conversion in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(17):7038-43.
2013: Anders Björklund; Jeffrey H Kordower
Cell therapy for Parkinson's disease: what next?
Movement disorders : official journal of the Movement Disorder Society 2013;28(1):110-5.
2012: Mickael Decressac; Banafsheh Kadkhodaei; Ariadna Laguna; Bengt Mattsson; Thomas Perlmann; Anders Björklund
α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons.
Science translational medicine 2012;4(163):163ra156.
2012: Eunju Shin; Christian Winkler; Anders Björklund; Joanna Garcia; Manolo Carta
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
Neurobiology of disease 2012;47(3):393-406.
2012: Elisabetta Tronci; Eunju Shin; Anders Björklund; Manolo Carta
Amphetamine-induced rotation and L-DOPA-induced dyskinesia in the rat 6-OHDA model: a correlation study.
Neuroscience research 2012;73(2):168-72.
2012: Malin Parmar; Anders Björklund
Generation of transplantable striatal projection neurons from human ESCs.
Cell stem cell 2012;10(4):349-50.
2012: M Decressac; Martin Lundblad; B Mattsson; P Weikop; Anders Björklund
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
Neurobiology of disease 2012;45(3):939-53.
2012: Martin Lundblad; Bengt Mattsson; Mickael Decressac; Anders Björklund
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(9):3213-9.
2012: Stephen B Dunnett; Anders Björklund
Functional neural transplantation III. Primary and stem cell therapies for brain repair, part I. Introduction.
Progress in brain research 2012;200():3-5.
2012: Stephen B Dunnett; Anders Björklund
Introduction (Part II).
Progress in brain research 2012;201():3-5.
2012: Elodie Angot; Anders Björklund; Peter Ekström; Carla M Lema Tomé; Bengt Mattsson; Jennifer A Steiner; Patrik Brundin
Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo.
PloS one 2012;7(6):e39465.
2011: Olle Lindvall; Anders Björklund
Cell therapeutics in Parkinson's disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2011;8(4):539-48.
2011: Marios Politis; Niall Quinn; Kit Wu; Oliver Pogarell; Anders Björklund; David J Brooks; Olle Lindvall; Wolfgang H Oertel; Paola Piccini
Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio.
Movement disorders : official journal of the Movement Disorder Society 2011;26(11):1997-2003.
2011: Ulrich Pfisterer; Olof Torper; James Wood; Anders Björklund; Audrey Dufour; Johan Jakobsson; Agnete Kirkeby; Olle Lindvall; Jenny Nelander; Malin Parmar
Direct conversion of human fibroblasts to dopaminergic neurons.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(25):10343-8.
2011: Anders Björklund; Tomas Björklund
Gene therapy for Parkinson's disease shows promise.
Science translational medicine 2011;3(79):79ed1.
2010: Marios Politis; Kit Wu; Clare Loane; Niall Quinn; David J Brooks; Stig Rehncrona; Anders Björklund; Olle Lindvall; Paola Piccini
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants.
Science translational medicine 2010;2(38):38ra46.
2010: Rohit Sachdeva; Marie E Jönsson; Jenny Nelander; Agnete Kirkeby; Carolina Guibentif; Bernhard Gentner; Luigi Naldini; Anders Björklund; Malin Parmar; Johan Jakobsson
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(25):11602-7.
2010: Jia-Yi Li; Elisabet Englund; Håkan Widner; Stig Rehncrona; Anders Björklund; Olle Lindvall; Patrik Brundin
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25(8):1091-6.
2010: Shane Grealish; Bengt Mattsson; Peter Draxler; Anders Björklund
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
The European journal of neuroscience 2010;31(12):2266-78.
2010: Shane Grealish; Marie E Jönsson; Meng Li; Deniz Kirik; Anders Björklund; Lachlan H Thompson
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease.
Brain : a journal of neurology 2010;133(Pt 2):482-95.
2010: Emma L Lane; Anders Björklund; Stephen B Dunnett; Christian Winkler
Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia.
Progress in brain research 2010;184():295-309.
2010: Ayse Ulusoy; Mickael Decressac; Deniz Kirik; Anders Björklund
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease.
Progress in brain research 2010;184():89-111.
2010: Manolo Carta; Thomas Carlsson; Ana Muñoz; Deniz Kirik; Anders Björklund
Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25 Suppl 1():S174-9.
2009: Anders Björklund; Tomas Björklund; Deniz Kirik
Gene therapy for dopamine replacement in Parkinson's disease.
Science translational medicine 2009;1(2):2ps2.
2009: Marie E Jönsson; Yuichi Ono; Anders Björklund; Lachlan H Thompson
Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis.
Experimental neurology 2009;219(1):341-54.
2009: Ana Muñoz; Thomas Carlsson; Elisabetta Tronci; Deniz Kirik; Anders Björklund; Mario Carta
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model.
Experimental neurology 2009;219(1):298-307.
2009: Lachlan H Thompson; Shane Grealish; Deniz Kirik; Anders Björklund
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain.
The European journal of neuroscience 2009;30(4):625-38.
2009: Thomas Carlsson; Manolo Carta; Ana Muñoz; Bengt Mattsson; Christian Winkler; Deniz Kirik; Anders Björklund
Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration.
Brain : a journal of neurology 2009;132(Pt 2):319-35.
2008: Ana Muñoz; Qin Li; Fabrizio Gardoni; Elena Marcello; Chuan Qin; Thomas Carlsson; Deniz Kirik; Monica Di Luca; Anders Björklund; Erwan Bezard; Manolo Carta
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.
Brain : a journal of neurology 2008;131(Pt 12):3380-94.
2008: Lachlan H Thompson; Deniz Kirik; Anders Björklund
Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain.
Experimental neurology 2008;213(1):220-8.
2008: Dwain K Irvin; Deniz Kirik; Anders Björklund; Lachlan H Thompson
In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway.
Neurobiology of disease 2008;30(3):343-52.
2008: Jens Nygren; Karina Liuba; Martin Breitbach; Simon Stott; Lina Thorén; Wilhelm Roell; Caroline Geisen; Philipp Sasse; Deniz Kirik; Anders Björklund; Claus Nerlov; Bernd K Fleischmann; Stefan Jovinge; Sten Eirik W Jacobsen
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
Nature cell biology 2008;10(5):584-92.
2008: Jia-Yi Li; Elisabet Englund; Janice L Holton; Denis Soulet; Peter Hagell; Andrew J Lees; Tammaryn Lashley; Niall Quinn; Stig Rehncrona; Anders Björklund; Håkan Widner; Tamas Revesz; Olle Lindvall; Patrik Brundin
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
Nature medicine 2008;14(5):501-3.
2008: K Kullberg; Anna Cristina Aberg; Anders Björklund; J Ekblad; Birgitta Sidenvall
Daily eating events among co-living and single-living, diseased older men.
The journal of nutrition, health & aging 2008;12(3):176-82.
2008: Manolo Carta; Thomas Carlsson; Ana Muñoz; Deniz Kirik; Anders Björklund
Serotonin-dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias.
Progress in brain research 2008;172():465-78.
2008: Manolo Carta; Thomas Carlsson; Ana Muñoz; Deniz Kirik; Anders Björklund
Involvement of the serotonin system in L-dopa-induced dyskinesias.
Parkinsonism & related disorders 2008;14 Suppl 2():S154-8.
2007: Anders Björklund; Johan Aschan; Myriam Labopin; Mats Remberger; Olle Ringden; Jacek Winiarski; Per Ljungman
Risk factors for fatal infectious complications developing late after allogeneic stem cell transplantation.
Bone marrow transplantation 2007;40(11):1055-62.
2007: Thomas Carlsson; Manolo Carta; Christian Winkler; Anders Björklund; Deniz Kirik
Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(30):8011-22.
2007: Manolo Carta; Thomas Carlsson; Deniz Kirik; Anders Björklund
Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats.
Brain : a journal of neurology 2007;130(Pt 7):1819-33.
2007: Nathalie Breysse; Thomas Carlsson; Christian Winkler; Anders Björklund; Deniz Kirik
The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(22):5849-56.
2007: Anders Björklund; Stephen B Dunnett
Dopamine neuron systems in the brain: an update.
Trends in neurosciences 2007;30(5):194-202.
2007: Anders Björklund; Stephen B Dunnett
Fifty years of dopamine research.
Trends in neurosciences 2007;30(5):185-7.
2007: Perrine Barraud; Simon Stott; Kjeld Møllgård; Malin Parmar; Anders Björklund
In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.
Journal of neuroscience research 2007;85(2):250-9.
2006: Lachlan H Thompson; Elin Andersson; Josephine B Jensen; Perrine Barraud; Francois Guillemot; Malin Parmar; Anders Björklund
Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.
Experimental neurology 2006;198(1):183-98.
2006: Thomas Carlsson; Christian Winkler; Martin Lundblad; M Angela Cenci; Anders Björklund; Deniz Kirik
Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia.
Neurobiology of disease 2006;21(3):657-68.
2006: Elin Andersson; Josephine B Jensen; Malin Parmar; F Guillemot; Anders Björklund
Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2.
Development (Cambridge, England) 2006;133(3):507-16.
2005: Paola Piccini; Nicola Pavese; Peter Hagell; Jan Reimer; Anders Björklund; Wolfgang H Oertel; Niall Quinn; David J Brooks; Olle Lindvall
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease.
Brain : a journal of neurology 2005;128(Pt 12):2977-86.
2005: Perrine Barraud; Lachlan Thompson; Deniz Kirik; Anders Björklund; Malin Parmar
Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.
The European journal of neuroscience 2005;22(7):1555-69.
2005: Young-Hwan Ahn; Jean-Charles Bensadoun; Patrick Aebischer; Anne D Zurn; Ake Seiger; Anders Björklund; Olle Lindvall; Lars U Wahlberg; Patrik Brundin; Gabriele S Kaminski Schierle
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor.
Brain research bulletin 2005;66(2):135-42.
2005: Lachlan Thompson; Perrine Barraud; Elin Andersson; Deniz Kirik; Anders Björklund
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(27):6467-77.
2005: Deniz Kirik; Anders Björklund
Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results.
Brain : a journal of neurology 2005;128(Pt 7):1478-9.
2005: Andreas Toft Sørensen; Lachlan Thompson; Deniz Kirik; Anders Björklund; Olle Lindvall; Merab Kokaia
Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.
The European journal of neuroscience 2005;21(10):2793-9.
2005: Thomas Carlsson; Christian Winkler; Corinna Burger; Nicholas Muzyczka; Ronald J Mandel; Angela Cenci; Anders Björklund; Deniz Kirik
Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors.
Brain : a journal of neurology 2005;128(Pt 3):559-69.
2005: Christian Winkler; Deniz Kirik; Anders Björklund
Cell transplantation in Parkinson's disease: how can we make it work?
Trends in neurosciences 2005;28(2):86-92.
2005: Anders Björklund
Cell therapy for Parkinson's disease: problems and prospects.
Novartis Foundation symposium 2005;265():174-86; discussion 187, 204-211.
2004: Josephine B Jensen; Anders Björklund; Malin Parmar
Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(31):6958-67.
2004: Biljana Georgievska; Deniz Kirik; Anders Björklund
Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6437-45.
2004: Deniz Kirik; Biljana Georgievska; Anders Björklund
Localized striatal delivery of GDNF as a treatment for Parkinson disease.
Nature neuroscience 2004;7(2):105-10.
2003: Cecilia Eriksson; Anders Björklund; Klas Wictorin
Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions.
Experimental neurology 2003;184(2):615-35.
2003: Malin Parmar; Andreas Sjöberg; Anders Björklund; Zaal Kokaia
Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro.
Molecular and cellular neurosciences 2003;24(3):741-52.
2003: Deniz Kirik; Anders Björklund
Modeling CNS neurodegeneration by overexpression of disease-causing proteins using viral vectors.
Trends in neurosciences 2003;26(7):386-92.
2003: Anders Björklund; Stephen B Dunnett; Patrik Brundin; A Jon Stoessl; Curt R Freed; Robert E Breeze; Marc Levivier; Marc Peschanski; Studer Lorenz; Roger A Barker
Neural transplantation for the treatment of Parkinson's disease.
Lancet neurology 2003;2(7):437-45.
2003: Deniz Kirik; Lucy E Annett; Corinna Burger; Nicholas Muzyczka; Ronald J Mandel; Anders Björklund
Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2884-9.
2003: C Winkler; C Bentlage; M A Cenci; G Nikkhah; Anders Björklund
Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model.
Neuroscience 2003;118(4):1063-77.
2002: Ulrica Englund; Anders Björklund; Klas Wictorin; Olle Lindvall; Merab Kokaia
Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):17089-94.
2002: Malin Parmar; Charlotta Skogh; Anders Björklund; Kenneth Campbell
Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon.
Molecular and cellular neurosciences 2002;21(4):645-56.
2002: Biljana Georgievska; Deniz Kirik; Anders Björklund
Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
Experimental neurology 2002;177(2):461-74.
2002: Christian Winkler; Deniz Kirik; Anders Björklund; M Angela Cenci
L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function.
Neurobiology of disease 2002;10(2):165-86.
2002: Peter Hagell; Paola Piccini; Anders Björklund; Patrik Brundin; Stig Rehncrona; Håkan Widner; Lesley Crabb; Nicola Pavese; Wolfgang H Oertel; Niall Quinn; David J Brooks; Olle Lindvall
Dyskinesias following neural transplantation in Parkinson's disease.
Nature neuroscience 2002;5(7):627-8.
2002: Cecilia Lundberg; Ulrica Englund; Didier Trono; Anders Björklund; Klas Wictorin
Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain.
Experimental neurology 2002;175(2):370-87.
2002: Deniz Kirik; Biljana Georgievska; Corinna Burger; Christian Winkler; Nicholas Muzyczka; Ronald J Mandel; Anders Björklund
Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4708-13.
2002: Deniz Kirik; Carl Rosenblad; Corinna Burger; Cecilia Lundberg; Teit E Johansen; Nicholas Muzyczka; Ronald J Mandel; Anders Björklund
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2780-91.
2002: Ulrica Englund; Anders Björklund; Klas Wictorin
Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain.
Brain research. Developmental brain research 2002;134(1-2):123-41.
2002: Biljana Georgievska; Deniz Kirik; Carl Rosenblad; Cecilia Lundberg; Anders Björklund
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector.
Neuroreport 2002;13(1):75-82.
2002: Ulrica Englund; Rosemary A Fricker-Gates; Cecilia Lundberg; Anders Björklund; Klas Wictorin
Transplantation of human neural progenitor cells into the neonatal rat brain: extensive migration and differentiation with long-distance axonal projections.
Experimental neurology 2002;173(1):1-21.
2001: Patrik Brundin; Stephen B Dunnett; Anders Björklund; G Nikkhah
Transplanted dopaminergic neurons: more or less?
Nature medicine 2001;7(5):512-3.
2001: Deniz Kirik; Christian Winkler; Anders Björklund
Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(8):2889-96.
2001: Deniz Kirik; Biljana Georgievska; Carl Rosenblad; Anders Björklund
Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease.
The European journal of neuroscience 2001;13(8):1589-99.
2001: Elisabetta Vaudano; Carl Rosenblad; Anders Björklund
Injury induced c-Jun expression and phosphorylation in the dopaminergic nigral neurons of the rat: correlation with neuronal death and modulation by glial-cell-line-derived neurotrophic factor.
The European journal of neuroscience 2001;13(1):1-14.
2000: Anders Björklund; Deniz Kirik; Carl Rosenblad; Biljana Georgievska; Cecilia Lundberg; Ronald J Mandel
Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model.
Brain research 2000;886(1-2):82-98.
2000: O Lindvall; Anders Björklund
First step towards cell therapy for Huntington's disease.
Lancet 2000;356(9246):1945-6.
2000: Paola Piccini; Olle Lindvall; Anders Björklund; Patrik Brundin; Peter Hagell; Roberto Ceravolo; Wolfgang H Oertel; Niall Quinn; M Samuel; Stig Rehncrona; Håkan Widner; David J Brooks
Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts.
Annals of neurology 2000;48(5):689-95.
2000: Deniz Kirik; Carl Rosenblad; Anders Björklund
Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor.
The European journal of neuroscience 2000;12(11):3871-82.
2000: Anders Björklund; O Lindvall
Parkinson disease gene therapy moves toward the clinic.
Nature medicine 2000;6(11):1207-8.
2000: Rosemary A Fricker-Gates; Christian Winkler; Deniz Kirik; Carl Rosenblad; MK Carpenter; Anders Björklund
EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum.
Experimental neurology 2000;165(2):237-47.
2000: Patrik Brundin; O Pogarell; Peter Hagell; Paola Piccini; Håkan Widner; A Schrag; Andreas Kupsch; Lesley Crabb; P Odin; B Gustavii; Anders Björklund; David J Brooks; CD Marsden; Wolfgang H Oertel; Niall Quinn; Stig Rehncrona; Olle Lindvall
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease.
Brain : a journal of neurology 2000;123 ( Pt 7)():1380-90.
2000: Deniz Kirik; Carl Rosenblad; Anders Björklund; Ronald J Mandel
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(12):4686-700.
2000: Carl Rosenblad; Deniz Kirik; Anders Björklund
Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.
Experimental neurology 2000;161(2):503-16.
2000: Carl Rosenblad; Mette Grønborg; C Hansen; Nikolaj Blom; M Meyer; Jens Johansen; Lone Dagø; Deniz Kirik; U A Patel; Cecilia Lundberg; Didier Trono; Anders Björklund; Teit E Johansen
In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin.
Molecular and cellular neurosciences 2000;15(2):199-214.
2000: Stephen B Dunnett; F Nathwani; Anders Björklund
The integration and function of striatal grafts.
Progress in brain research 2000;127():345-80.
2000: Christian Winkler; Deniz Kirik; Anders Björklund; Stephen B Dunnett
Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement.
Progress in brain research 2000;127():233-65.
2000: Anders Björklund
Cell replacement strategies for neurodegenerative disorders.
Novartis Foundation symposium 2000;231():7-15; discussion 16-20.
1999: Paola Piccini; David J Brooks; Anders Björklund; Roger Gunn; Paul M Grasby; Ornella E Rimoldi; Patrik Brundin; Peter Hagell; Stig Rehncrona; Håkan Widner; Olle Lindvall
Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient.
Nature neuroscience 1999;2(12):1137-40.
1999: C Bentlage; G Nikkhah; M G Cunningham; Anders Björklund
Reformation of the nigrostriatal pathway by fetal dopaminergic micrografts into the substantia nigra is critically dependent on the age of the host.
Experimental neurology 1999;159(1):177-90.
1999: RA Fricker; MK Carpenter; Christian Winkler; C Greco; MA Gates; Anders Björklund
Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(14):5990-6005.
1999: Carl Rosenblad; Deniz Kirik; Anders Björklund
Neurturin enhances the survival of intrastriatal fetal dopaminergic transplants.
Neuroreport 1999;10(8):1783-7.
1999: Peter Hagell; A Schrag; Paola Piccini; Marjan Jahanshahi; R Brown; Stig Rehncrona; Håkan Widner; Patrik Brundin; John C Rothwell; P Odin; Gregor Wenning; PK Morrish; B Gustavii; Anders Björklund; David J Brooks; CD Marsden; Niall Quinn; Olle Lindvall
Sequential bilateral transplantation in Parkinson's disease: effects of the second graft.
Brain : a journal of neurology 1999;122 ( Pt 6)():1121-32.
1999: Carl Rosenblad; Deniz Kirik; Brigitte Devaux; Barbara Moffat; Heidi S Phillips; Anders Björklund
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle.
The European journal of neuroscience 1999;11(5):1554-66.
1999: Anders Björklund; Clive Svendsen
Stem cells. Breaking the brain-blood barrier.
Nature 1999;397(6720):569-70.
1999: C Winkler; C Bentlage; G Nikkhah; Madjid Samii; Anders Björklund
Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants.
Experimental neurology 1999;155(2):165-86.
1998: Patrik Brundin; Anders Björklund
Survival of expanded dopaminergic precursors is critical for clinical trials.
Nature neuroscience 1998;1(7):537.
1998: Deniz Kirik; Carl Rosenblad; Anders Björklund
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat.
Experimental neurology 1998;152(2):259-77.
1998: G Leanza; A Martìnez-Serrano; Anders Björklund
Amelioration of spatial navigation and short-term memory deficits by grafts of foetal basal forebrain tissue placed into the hippocampus and cortex of rats with selective cholinergic lesions.
The European journal of neuroscience 1998;10(7):2353-70.
1998: B A Horger; Merry Nishimura; Mark P Armanini; LC Wang; Kris T Poulsen; Carl Rosenblad; Deniz Kirik; Barbara Moffat; Laura Simmons; E Johnson; Jeffrey Milbrandt; Arnon Rosenthal; Anders Björklund; Richard Vandlen; Mary Hynes; Heidi S Phillips
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(13):4929-37.
1998: Gunnar Andsberg; Zaal Kokaia; Anders Björklund; Olle Lindvall; Alberto Martínez-Serrano
Amelioration of ischaemia-induced neuronal death in the rat striatum by NGF-secreting neural stem cells.
The European journal of neuroscience 1998;10(6):2026-36.
1998: Christian Winkler; RA Fricker; MA Gates; M Olsson; JP Hammang; MK Carpenter; Anders Björklund
Incorporation and glial differentiation of mouse EGF-responsive neural progenitor cells after transplantation into the embryonic rat brain.
Molecular and cellular neurosciences 1998;11(3):99-116.
1998: M A Gates; M Olsson; K Bjerregaard; Anders Björklund
Region-specific migration of embryonic glia grafted to the neonatal brain.
Neuroscience 1998;84(4):1013-23.
1998: A Martínez-Serrano; M Olsson; M A Gates; Anders Björklund
In utero gene transfer reveals survival effects of nerve growth factor on rat brain cholinergic neurones during development.
The European journal of neuroscience 1998;10(1):263-71.
1998: M Olsson; K Bjerregaard; Christian Winkler; M Gates; Anders Björklund; K Campbell
Incorporation of mouse neural progenitors transplanted into the rat embryonic forebrain is developmentally regulated and dependent on regional and adhesive properties.
The European journal of neuroscience 1998;10(1):71-85.
1998: Carl Rosenblad; A Martinez-Serrano; Anders Björklund
Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson's disease.
Neuroscience 1998;82(1):129-37.
1997: MK Carpenter; Christian Winkler; RA Fricker; DF Emerich; S C Wong; C Greco; Er-Yun Chen; Y Chu; Jeffrey Kordower; A Messing; Anders Björklund; JP Hammang
Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice.
Experimental neurology 1997;148(1):187-204.
1997: Alberto Martínez-Serrano; Anders Björklund
Immortalized neural progenitor cells for CNS gene transfer and repair.
Trends in neurosciences 1997;20(11):530-8.
1997: Jeffrey Kordower; Er-Yun Chen; C Winkler; RA Fricker; Vinod Charles; A Messing; Elliott J Mufson; S C Wong; J M Rosenstein; Anders Björklund; DF Emerich; JP Hammang; MK Carpenter
Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.
The Journal of comparative neurology 1997;387(1):96-113.
1997: Gregor Wenning; P Odin; PK Morrish; Stig Rehncrona; Håkan Widner; Patrik Brundin; John C Rothwell; Richard G Brown; B Gustavii; Peter Hagell; Marjan Jahanshahi; Guy V Sawle; Anders Björklund; David J Brooks; CD Marsden; Niall Quinn; Olle Lindvall
Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease.
Annals of neurology 1997;42(1):95-107.
1997: M Olsson; C Bentlage; Klas Wictorin; K Campbell; Anders Björklund
Extensive migration and target innervation by striatal precursors after grafting into the neonatal striatum.
Neuroscience 1997;79(1):57-78.
1997: Cecilia Lundberg; A Martínez-Serrano; Elena Cattaneo; R D McKay; Anders Björklund
Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum.
Experimental neurology 1997;145(2 Pt 1):342-60.
1997: Stephen B Dunnett; Anders Björklund
Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain.
Brain research. Brain research protocols 1997;1(1):91-9.
1997: Anders Björklund; Carl Rosenblad; Christian Winkler; Deniz Kirik
Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease.
Neurobiology of disease 1997;4(3-4):186-200.
1996: Carl Rosenblad; A Martinez-Serrano; Anders Björklund
Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts.
Neuroscience 1996;75(4):979-85.
1996: G Leanza; J Muir; O G Nilsson; R G Wiley; Stephen B Dunnett; Anders Björklund
Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term memory in rats.
The European journal of neuroscience 1996;8(7):1535-44.
1996: C S Lee; H Sauer; Anders Björklund
Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat.
Neuroscience 1996;72(3):641-53.
1995: A Martínez-Serrano; C Lundberg; P Horellou; W Fischer; C Bentlage; K Campbell; Ronald D G McKay; J Mallet; Anders Björklund
CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after transplantation into the septum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(8):5668-80.
1995: G Nikkhah; J Eberhard; M Olsson; Anders Björklund
Preservation of fetal ventral mesencephalic cells by cool storage: in-vitro viability and TH-positive neuron survival after microtransplantation to the striatum.
Brain research 1995;687(1-2):22-34.
1995: M Olsson; G Nikkhah; C Bentlage; Anders Björklund
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 2):3863-75.
1995: G Nikkhah; M G Cunningham; R McKay; Anders Björklund
Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. II. Transplant-induced behavioral recovery.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 1):3562-70.
1995: G Nikkhah; M G Cunningham; M A Cenci; Ronald D G McKay; Anders Björklund
Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. I. Evidence for anatomical reconstruction of the nigrostriatal pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 1):3548-61.
1994: Merab Kokaia; M A Cenci; Eskil Elmér; O G Nilsson; Zaal Kokaia; Johan Bengzon; Anders Björklund; Olle Lindvall
Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocampus by superior cervical ganglion or fetal locus coeruleus grafts.
Experimental neurology 1994;130(2):351-61.
1994: G Nikkhah; M Olsson; J Eberhard; C Bentlage; M G Cunningham; Anders Björklund
A microtransplantation approach for cell suspension grafting in the rat Parkinson model: a detailed account of the methodology.
Neuroscience 1994;63(1):57-72.
1994: W Fischer; A Sirevaag; S J Wiegand; Ronald Lindsay; Anders Björklund
Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8607-11.
1994: G Nikkhah; C Bentlage; M G Cunningham; Anders Björklund
Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(6):3449-61.
1994: Olle Lindvall; Guy V Sawle; Håkan Widner; John C Rothwell; Anders Björklund; David J Brooks; Patrik Brundin; Richard S J Frackowiak; CD Marsden; P Odin
Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease.
Annals of neurology 1994;35(2):172-80.
1994: H Sauer; K Campbell; S J Wiegand; Ronald Lindsay; Anders Björklund
Brain-derived neurotrophic factor enhances striatal neuropeptide expression in both the intact and the dopamine-depleted rat striatum.
Neuroreport 1994;5(5):609-12.
1994: G Nikkhah; M G Cunningham; Andreas Jödicke; U Knappe; Anders Björklund
Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model.
Brain research 1994;633(1-2):133-43.
1993: WM Duan; Håkan Widner; Anders Björklund; Patrik Brundin
Sequential intrastriatal grafting of allogeneic embryonic dopamine-rich neuronal tissue in adult rats: will the second graft be rejected?
Neuroscience 1993;57(2):261-74.
1993: H Sauer; W Fischer; G Nikkhah; S J Wiegand; Patrik Brundin; Ronald Lindsay; Anders Björklund
Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts.
Brain research 1993;626(1-2):37-44.
1993: G Nikkhah; W M Duan; U Knappe; Andreas Jödicke; Anders Björklund
Restoration of complex sensorimotor behavior and skilled forelimb use by a modified nigral cell suspension transplantation approach in the rat Parkinson model.
Neuroscience 1993;56(1):33-43.
1993: Håkan Widner; J Tetrud; Stig Rehncrona; B J Snow; Patrik Brundin; Anders Björklund; Olle Lindvall; J William Langston
Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism.
Advances in neurology 1993;60():729-33.
1992: Håkan Widner; J Tetrud; Stig Rehncrona; B Snow; Patrik Brundin; B Gustavii; Anders Björklund; Olle Lindvall; J William Langston
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
The New England journal of medicine 1992;327(22):1556-63.
1992: K Wictorin; Patrik Brundin; H Sauer; Olle Lindvall; Anders Björklund
Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats.
The Journal of comparative neurology 1992;323(4):475-94.
1992: Guy V Sawle; Peter M Bloomfield; Anders Björklund; David J Brooks; Patrik Brundin; Klaus L Leenders; Olle Lindvall; CD Marsden; Stig Rehncrona; Håkan Widner
Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants.
Annals of neurology 1992;31(2):166-73.
1992: Olle Lindvall; Anders Björklund
Intracerebral grafting of inhibitory neurons. A new strategy for seizure suppression in the central nervous system.
Advances in neurology 1992;57():561-9.
1991: Håkan Widner; Patrik Brundin; Stig Rehncrona; B Gustavii; Richard S J Frackowiak; Klaus L Leenders; Guy V Sawle; John C Rothwell; CD Marsden; Anders Björklund
Transplanted allogeneic fetal dopamine neurons survive and improve motor function in idiopathic Parkinson's disease.
Transplantation proceedings 1991;23(1 Pt 1):793-5.
1991: Philippe Horellou; C Lundberg; B Le Bourdellès; K Wictorin; Patrik Brundin; P Kalén; Anders Björklund; Jacques Mallet
Behavioural effects of genetically engineered cells releasing dopa and dopamine after intracerebral grafting in a rat model of Parkinson's disease.
Journal de physiologie 1991;85(3):158-70.
1990: Y Murata; T Chiba; Patrik Brundin; Anders Björklund; O Lindvall
Formation of synaptic graft-host connections by noradrenergic locus coeruleus neurons transplanted into the adult rat hippocampus.
Experimental neurology 1990;110(3):258-67.
1990: K Wictorin; Patrik Brundin; B Gustavii; Olle Lindvall; Anders Björklund
Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts.
Nature 1990;347(6293):556-8.
1990: Philippe Horellou; Patrik Brundin; P Kalén; Jacques Mallet; Anders Björklund
In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum.
Neuron 1990;5(4):393-402.
1990: P Kalén; O G Nilsson; M A Cenci; E Rosengren; Olle Lindvall; Anders Björklund
Intracerebral microdialysis as a tool to monitor transmitter release from grafted cholinergic and monoaminergic neurons.
Journal of neuroscience methods 1990;34(1-3):107-15.
1990: O G Nilsson; Patrik Brundin; Anders Björklund
Amelioration of spatial memory impairment by intrahippocampal grafts of mixed septal and raphe tissue in rats with combined cholinergic and serotonergic denervation of the forebrain.
Brain research 1990;515(1-2):193-206.
1990: D J Clarke; O G Nilsson; Patrik Brundin; Anders Björklund
Synaptic connections formed by grafts of different types of cholinergic neurons in the host hippocampus.
Experimental neurology 1990;107(1):11-22.
1990: Olle Lindvall; Stig Rehncrona; Patrik Brundin; B Gustavii; B Astedt; Håkan Widner; T Lindholm; Anders Björklund; Klaus L Leenders; John C Rothwell
Neural transplantation in Parkinson's disease: the Swedish experience.
Progress in brain research 1990;82():729-34.
1990: Patrik Brundin; Anders Björklund; Olle Lindvall
Practical aspects of the use of human fetal brain tissue for intracerebral grafting.
Progress in brain research 1990;82():707-14.
1990: P Kalén; M A Cenci; A Daszuta; Olle Lindvall; Anders Björklund
In vivo microdialysis: a new approach for the study of functional activity of grafted monoaminergic neurons and their interaction with the host brain.
Progress in brain research 1990;82():329-38.
1990: Lazaros C Triarhou; Patrik Brundin; G Doucet; J Norton; Anders Björklund; Bernardino Ghetti
Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;79(1):3-17.
1990: K Wictorin; D J Clarke; J P Bolam; Patrik Brundin; B Gustavii; Olle Lindvall; Anders Björklund
Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing.
Progress in brain research 1990;82():391-9.
1989: D I Barry; B Wanscher; J Kragh; Tom G Bolwig; M Kokaia; Patrik Brundin; Anders Björklund; O Lindvall
Grafts of fetal locus coeruleus neurons in rat amygdala-piriform cortex suppress seizure development in hippocampal kindling.
Experimental neurology 1989;106(2):125-32.
1989: A Daszuta; P Kalén; R E Strecker; Patrik Brundin; Anders Björklund
Serotonin neurons grafted to the adult rat hippocampus. II. 5-HT release as studied by intracerebral microdialysis.
Brain research 1989;498(2):323-32.
1989: Guy Doucet; Y Murata; Patrik Brundin; Olivier Bosler; N Mons; M Geffard; C C Ouimet; Anders Björklund
Host afferents into intrastriatal transplants of fetal ventral mesencephalon.
Experimental neurology 1989;106(1):1-19.
1989: Fred H Gage; Stephen B Dunnett; Anders Björklund
Age-related impairments in spatial memory are independent of those in sensorimotor skills.
Neurobiology of aging 1989;10(4):347-52.
1989: Olle Lindvall; Stig Rehncrona; Patrik Brundin; B Gustavii; B Astedt; Håkan Widner; T Lindholm; Anders Björklund; Klaus L Leenders; John C Rothwell; R Frackowiak; D Marsden; B Johnels; G Steg; R Freedman; B J Hoffer; A Seiger; M Bygdeman; I Strömberg; L Olson
Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up.
Archives of neurology 1989;46(6):615-31.
1989: Fred H Gage; P Batchelor; K S Chen; D Chin; Gerry Higgins; S Koh; S Deputy; M B Rosenberg; W Fischer; Anders Björklund
NGF receptor reexpression and NGF-mediated cholinergic neuronal hypertrophy in the damaged adult neostriatum.
Neuron 1989;2(2):1177-84.
1989: P Kalén; Olle Lindvall; Anders Björklund
Electrical stimulation of the lateral habenula increases hippocampal noradrenaline release as monitored by in vivo microdialysis.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;76(1):239-45.
1989: Håkan Widner; Patrik Brundin; Anders Björklund; E Möller
Survival and immunogenicity of dissociated allogeneic fetal neural dopamine-rich grafts when implanted into the brains of adult mice.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;76(1):187-97.
1989: K Wictorin; R B Simerly; Ole Isacson; L W Swanson; Anders Björklund
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum--III. Efferent projecting graft neurons and their relation to host afferents within the grafts.
Neuroscience 1989;30(2):313-30.
1989: Olle Lindvall; Anders Björklund
Transplantation strategies in the treatment of Parkinson's disease: experimental basis and clinical trials.
Acta neurologica Scandinavica. Supplementum 1989;126():197-210.
1989: G Doucet; Patrik Brundin; S Seth; Y Murata; R E Strecker; Lazaros C Triarhou; Bernardino Ghetti; Anders Björklund
Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;77(3):552-68.
1989: C Forni; Patrik Brundin; R E Strecker; S el Ganouni; Anders Björklund; A Nieoullon
Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;76(1):75-87.
1989: Patrik Brundin; Håkan Widner; O G Nilsson; R E Strecker; Anders Björklund
Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;75(1):195-207.
1988: O Lindvall; Stig Rehncrona; B Gustavii; Patrik Brundin; B Astedt; Håkan Widner; T Lindholm; Anders Björklund; Klaus L Leenders; John C Rothwell; R Frackowiak; C D Marsden; B Johnels; G Steg; R Freedman; B J Hoffer; L Seiger; I Strömberg; M Bygdeman; L Olson
Fetal dopamine-rich mesencephalic grafts in Parkinson's disease.
Lancet 1988;2(8626-8627):1483-4.
1988: P Kalén; Merab Kokaia; Olle Lindvall; Anders Björklund
Basic characteristics of noradrenaline release in the hippocampus of intact and 6-hydroxydopamine-lesioned rats as studied by in vivo microdialysis.
Brain research 1988;474(2):374-9.
1988: K Wictorin; Ole Isacson; W Fischer; F Nothias; Marc Peschanski; Anders Björklund
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum--I. Subcortical afferents.
Neuroscience 1988;27(2):547-62.
1988: F Nothias; K Wictorin; Ole Isacson; Anders Björklund; Marc Peschanski
Morphological alteration of thalamic afferents in the excitotoxically lesioned striatum.
Brain research 1988;461(2):349-54.
1988: A Daszuta; R E Strecker; Patrik Brundin; Anders Björklund
Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry.
Brain research 1988;458(1):1-19.
1988: O G Nilsson; Patrik Brundin; Håkan Widner; R E Strecker; Anders Björklund
Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern.
Brain research 1988;456(1):193-8.
1988: Patrik Brundin; G Barbin; R E Strecker; Ole Isacson; A Prochiantz; Anders Björklund
Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro.
Brain research 1988;467(2):233-43.
1988: Stephen B Dunnett; Ole Isacson; D J Sirinathsinghji; D J Clarke; Anders Björklund
Striatal grafts in rats with unilateral neostriatal lesions--III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching.
Neuroscience 1988;24(3):813-20.
1988: D J Sirinathsinghji; Stephen B Dunnett; Ole Isacson; D J Clarke; Keith M Kendrick; Anders Björklund
Striatal grafts in rats with unilateral neostriatal lesions--II. In vivo monitoring of GABA release in globus pallidus and substantia nigra.
Neuroscience 1988;24(3):803-11.
1988: D J Clarke; Stephen B Dunnett; Ole Isacson; D J Sirinathsinghji; Anders Björklund
Striatal grafts in rats with unilateral neostriatal lesions--I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway.
Neuroscience 1988;24(3):791-801.
1988: O G Nilsson; D J Clarke; Patrik Brundin; Anders Björklund
Comparison of growth and reinnervation properties of cholinergic neurons from different brain regions grafted to the hippocampus.
The Journal of comparative neurology 1988;268(2):204-22.
1988: Patrik Brundin; R E Strecker; Håkan Widner; D J Clarke; O G Nilsson; B Astedt; Olle Lindvall; Anders Björklund
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1988;70(1):192-208.
1988: Fred H Gage; Patrik Brundin; R Strecker; Stephen B Dunnett; Ole Isacson; Anders Björklund
Intracerebral neuronal grafting in experimental animal models of age-related motor dysfunction.
Annals of the New York Academy of Sciences 1988;515():383-94.
1988: Anders Björklund; Patrik Brundin; Ole Isacson
Neuronal replacement by intracerebral neural implants in animal models of neurodegenerative disease.
Advances in neurology 1988;47():455-92.
1988: K Wictorin; Ole Isacson; W Fischer; F Nothias; Marc Peschanski; Anders Björklund
Studies on host afferent inputs to fetal striatal transplants in the excitotoxically lesioned striatum.
Progress in brain research 1988;78():55-60.
1988: D J Clarke; Stephen B Dunnett; Ole Isacson; Anders Björklund
Striatal grafts in the ibotenic acid-lesioned neostriatum: ultrastructural and immunocytochemical studies.
Progress in brain research 1988;78():47-53.
1988: W Fischer; K Wictorin; Ole Isacson; Anders Björklund
Trophic effects on cholinergic striatal interneurons by submaxillary gland transplants.
Progress in brain research 1988;78():409-12.
1988: Håkan Widner; Patrik Brundin; Anders Björklund; E Möller
Immunological aspects of neural grafting in the mammalian central nervous system.
Progress in brain research 1988;78():303-7.
1988: D J Clarke; Patrik Brundin; R E Strecker; O G Nilsson; Anders Björklund; Olle Lindvall
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1988;73(1):115-26.
1988: O Lindvall; D I Barry; I Kikvadze; Patrik Brundin; T G Bolwig; Anders Björklund
Intracerebral grafting of fetal noradrenergic locus coeruleus neurons: evidence for seizure suppression in the kindling model of epilepsy.
Progress in brain research 1988;78():79-86.
1988: Patrik Brundin; R E Strecker; D J Clarke; Håkan Widner; O G Nilsson; B Astedt; O Lindvall; Anders Björklund
Can human fetal dopamine neuron grafts provide a therapy for Parkinson's disease?
Progress in brain research 1988;78():441-8.
1988: Stephen B Dunnett; Ole Isacson; D J Sirinathsinghji; D J Clarke; Anders Björklund
Striatal grafts in the ibotenic acid-lesioned neostriatum: functional studies.
Progress in brain research 1988;78():39-45.
1988: Ole Isacson; K Wictorin; W Fischer; M V Sofroniew; Anders Björklund
Fetal cortical cell suspension grafts to the excitotoxically lesioned neocortex: anatomical and neurochemical studies of trophic interactions.
Progress in brain research 1988;78():13-26.
1988: Patrik Brundin; R E Strecker; F H Gage; Olle Lindvall; Anders Björklund
Intracerebral transplantation of dopamine neurons: understanding the functional role of the mesolimbocortical dopamine system and developing a therapy for Parkinson's disease.
Annals of the New York Academy of Sciences 1988;537():148-60.
1988: Menahem Segal; E Azmitia; Anders Björklund; V Greenberger; Gal Richter-Levin
Physiology of graft-host interactions in the rat hippocampus.
Progress in brain research 1988;78():95-101.
1987: D I Barry; I Kikvadze; Patrik Brundin; Tom G Bolwig; Anders Björklund; O Lindvall
Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8712-5.
1987: Ole Isacson; D Dawbarn; Patrik Brundin; F H Gage; P C Emson; Anders Björklund
Neural grafting in a rat model of Huntington's disease: striosomal-like organization of striatal grafts as revealed by acetylcholinesterase histochemistry, immunocytochemistry and receptor autoradiography.
Neuroscience 1987;22(2):481-97.
1987: R E Strecker; T Sharp; Patrik Brundin; T Zetterström; U Ungerstedt; Anders Björklund
Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis.
Neuroscience 1987;22(1):169-78.
1987: Ole Isacson; W Fischer; K Wictorin; D Dawbarn; Anders Björklund
Astroglial response in the excitotoxically lesioned neostriatum and its projection areas in the rat.
Neuroscience 1987;20(3):1043-56.
1987: Patrik Brundin; Anders Björklund
Survival, growth and function of dopaminergic neurons grafted to the brain.
Progress in brain research 1987;71():293-308.
1987: Ole Isacson; M Pritzel; D Dawbarn; Patrik Brundin; P A Kelly; L Wiklund; P C Emson; F H Gage; Stephen B Dunnett; Anders Björklund
Striatal neural transplants in the ibotenic acid-lesioned rat neostriatum. Cellular and functional aspects.
Annals of the New York Academy of Sciences 1987;495():537-55.
1987: Patrik Brundin; R E Strecker; E Londos; Anders Björklund
Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1987;69(1):183-94.
1986: L R Williams; S Varon; G M Peterson; K Wictorin; W Fischer; Anders Björklund; F H Gage
Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):9231-5.
1986: F H Gage; K Wictorin; W Fischer; L R Williams; S Varon; Anders Björklund
Retrograde cell changes in medial septum and diagonal band following fimbria-fornix transection: quantitative temporal analysis.
Neuroscience 1986;19(1):241-55.
1986: M V Sofroniew; Ole Isacson; Anders Björklund
Cortical grafts prevent atrophy of cholinergic basal nucleus neurons induced by excitotoxic cortical damage.
Brain research 1986;378(2):409-15.
1986: Ole Isacson; Stephen B Dunnett; Anders Björklund
Graft-induced behavioral recovery in an animal model of Huntington disease.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2728-32.
1986: Patrik Brundin; Ole Isacson; F H Gage; A Prochiantz; Anders Björklund
The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting.
Brain research 1986;366(1-2):346-9.
1986: T Zetterström; Patrik Brundin; F H Gage; T Sharp; Ole Isacson; Stephen B Dunnett; U Ungerstedt; Anders Björklund
In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis.
Brain research 1986;362(2):344-9.
1986: M V Sofroniew; R C Pearson; Ole Isacson; Anders Björklund
Experimental studies on the induction and prevention of retrograde degeneration of basal forebrain cholinergic neurons.
Progress in brain research 1986;70():363-89.
1986: Patrik Brundin; O G Nilsson; R E Strecker; Olle Lindvall; B Astedt; Anders Björklund
Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1986;65(1):235-40.
1986: Patrik Brundin; Ole Isacson; F H Gage; Anders Björklund
Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells.
Brain research 1986;389(1-2):77-84.
1986: M Pritzel; Ole Isacson; Patrik Brundin; L Wiklund; Anders Björklund
Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1986;65(1):112-26.
1985: Ole Isacson; Patrik Brundin; F H Gage; Anders Björklund
Neural grafting in a rat model of Huntington's disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting.
Neuroscience 1985;16(4):799-817.
1985: Patrik Brundin; G Barbin; Ole Isacson; Michel Mallat; B Chamak; Alain Prochiantz; F H Gage; Anders Björklund
Survival of intracerebrally grafted rat dopamine neurons previously cultured in vitro.
Neuroscience letters 1985;61(1-2):79-84.
1985: F H Gage; Patrik Brundin; Ole Isacson; Anders Björklund
Rat fetal brain tissue grafts survive and innervate host brain following five day pregraft tissue storage.
Neuroscience letters 1985;60(2):133-7.
1985: Menahem Segal; Anders Björklund; F H Gage
Transplanted septal neurons make viable cholinergic synapses with a host hippocampus.
Brain research 1985;336(2):302-7.
1985: Patrik Brundin; Ole Isacson; Anders Björklund
Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival.
Brain research 1985;331(2):251-9.
1985: Patrik Brundin; O G Nilsson; F H Gage; Anders Björklund
Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1985;60(1):204-8.
1985: M L Shapiro; D Simon; D S Olton; F H Gage; Anders Björklund; U Stenevi
Brain transplants: can they restore single unit activity in the hippocampus?
Annals of the New York Academy of Sciences 1985;444():536-7.
1985: P C Emson; D Dawbarn; Martin N Rossor; J F Rehfeld; Patrik Brundin; Ole Isacson; Anders Björklund
Cholecystokinin content in the basal ganglia in Huntington's disease. The expression of cholecystokinin immunoreactivity in striatal grafts to ibotenic acid-lesioned rat striatum.
Annals of the New York Academy of Sciences 1985;448():488-94.
1984: Ole Isacson; Patrik Brundin; P A Kelly; F H Gage; Anders Björklund
Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum.
Nature 1984;311(5985):458-60.
1983: F H Gage; Stephen B Dunnett; Patrik Brundin; Ole Isacson; Anders Björklund
Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application.
Developmental neuroscience 1983;6(3):137-51.
1981: Menahem Segal; U Stenevi; Anders Björklund
Reformation in adult rats of functional septo-hippocampal connections by septal neurons regenerating across an embryonic hippocampal tissue bridge.
Neuroscience letters 1981;27(1):7-12.
1979: Anders Björklund; Menahem Segal; U Stenevi
Functional reinnervation of rat hippocampus by locus coeruleus implants.
Brain research 1979;170(3):409-26.
1979: L F Kromer; Anders Björklund; U Stenevi
Intracephalic implants: a technique for studying neuronal interactions.
Science (New York, N.Y.) 1979;204(4397):1117-9.
1978: Kjeld Møllgård; J J Lundberg; B K Beebe; Anders Björklund; U Stenevi
The intracerebrally cultured 'microbrain': a new tool in developmental neurobiology.
Neuroscience letters 1978;8(4):295-301.
1978: F Stenevi; Anders Björklund
Growth of vascular sympathetic axons into the hippocampus after lesions of the septo-hippocampal pathway: a pitfall in brain lesion studies.
Neuroscience letters 1978;7(2-3):219-24.
1975: Anders Björklund; B Johansson; U Stenevi; N A Svendgaard
Re-establishment of functional connections by regenerating central adrenergic and cholinergic axons.
Nature 1975;253(5491):446-8.
1971: S Axelsson; Anders Björklund; N Seiler
Identification of bufotenin in toad brain by chromatography and mass spectrometry of its dans-derivative.
Life sciences. Pt. 1: Physiology and pharmacology 1971;10(13):745-9.
1971: K West; Anders Björklund; C Owman
Evidence of abortive regeneration of adrenergic fibers in rat mesencephalon.
Journal of neuropathology and experimental neurology 1971;30(1):135.