FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Michael Schäfer

Research Profile

Living Beings

Disorders

Chemicals & Drugs

Concepts & Ideas

Procedures

Anatomy

Co-author Network

Publications

TOP 3
Michael Schäfer
The painful Toll of ethanol and its metabolites: A new molecular pattern of recognition by Toll-like receptors?
Viola Spahn; Christoph Stein; Jeannette Endres-Becker; Oliver Fischer; Michael Schäfer; Christian Zöllner
Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner.
Shaaban A Mousa; Jan F Richter; Laura Schaad; Jonas Schneider; Mehdi Shakibaei; Mohammed Shaqura; Toni S Shippenberg; Christian Zöllner; Rainer Hellweg; Baled I Khalefa; Michael Schäfer
Rab7 silencing prevents μ-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Michael Schäfer (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Michael Schäfer
The painful Toll of ethanol and its metabolites: A new molecular pattern of recognition by Toll-like receptors?
Brain, behavior, and immunity 2013;30():22-3.
2013: Viola Spahn; Christoph Stein; Jeannette Endres-Becker; Oliver Fischer; Michael Schäfer; Christian Zöllner
Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner.
Pain 2013;154(4):598-608.
2013: Shaaban A Mousa; Jan F Richter; Laura Schaad; Jonas Schneider; Mehdi Shakibaei; Mohammed Shaqura; Toni S Shippenberg; Christian Zöllner; Rainer Hellweg; Baled I Khalefa; Michael Schäfer
Rab7 silencing prevents μ-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy.
Diabetes 2013;62(4):1308-19.
2012: B I Khalefa; Shaaban A Mousa; Mahmoud Al-Khrasani; Zsuzsanna Fürst; Mohammed A Shaqura; Michael Schäfer
Relative contributions of peripheral versus supraspinal or spinal opioid receptors to the antinociception of systemic opioids.
European journal of pain (London, England) 2012;16(5):690-705.
2011: Michael Schäfer
PAIN EDUCATION--a modular learning approach.
Current medical research and opinion 2011;27(10):2081-2.
2011: Shaaban A Mousa; Mohammed A Shaqura; Jörn Schäper; Sascha Treskatsch; Helmut Habazettl; Michael Schäfer; Hashim Abdul-Khaliq
Developmental expression of δ-opioid receptors during maturation of the parasympathetic, sympathetic, and sensory innervations of the neonatal heart: early targets for opioid regulation of autonomic control.
The Journal of comparative neurology 2011;519(5):957-71.
2011: Reine-Solange Yamdeu; Mohammed Shaqura; Shaaban A Mousa; Michael Schäfer; Jana Droese
p38 Mitogen-activated protein kinase activation by nerve growth factor in primary sensory neurons upregulates μ-opioid receptors to enhance opioid responsiveness toward better pain control.
Anesthesiology 2011;114(1):150-61.
2010: Shaaban A Mousa; Mohammed A Shaqura; Ute Brendl; Mahmoud Al-Khrasani; Zsuzsanna Fürst; Michael Schäfer
Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid-containing immune cells to inhibit inflammatory pain.
Brain, behavior, and immunity 2010;24(8):1310-23.
2010: Shaaban A Mousa; Mohammed A Shaqura; Jörn Schäper; Wei Huang; Sascha Treskatsch; Helmut Habazettl; Hashim Abdul-Khaliq; Michael Schäfer
Identification of mu- and kappa-opioid receptors as potential targets to regulate parasympathetic, sympathetic, and sensory neurons within rat intracardiac ganglia.
The Journal of comparative neurology 2010;518(18):3836-47.
2010: Jörn Schäper; Raees Ahmed; Frank Holger Perschel; Michael Schäfer; Helmut Habazettl; Martin Welte
Thoracic epidural anesthesia attenuates endotoxin-induced impairment of gastrointestinal organ perfusion.
Anesthesiology 2010;113(1):126-33.
2010: C A Müller; Michael Schäfer; Sylke Schneider; H M Heimann; Axel Hinzpeter; K Volkmar; A Förg; Andreas Heinz; J Hein
Efficacy and safety of levetiracetam for outpatient alcohol detoxification.
Pharmacopsychiatry 2010;43(5):184-9.
2010: Shaaban A Mousa; Malgorzata Krajnik; Piotr Sobanski; Janusz Kowalewski; Elzbieta Bloch-Boguslawska; Zbigniew Zylicz; Michael Schäfer
Dynorphin expression, processing and receptors in the alveolar macrophages, cancer cells and bronchial epithelium of lung cancer patients.
Histology and histopathology 2010;25(6):755-64.
2010: Michael Schäfer; Susanne Keilig; Alexander Brack; Peter Kranke
[Opioid induced cough: Do we know its pathophysiology and can it be eliminated?].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2010;45(3):170-3.
2009: Heike L Rittner; Dagmar Hackel; Philipp Voigt; Shaaban Mousa; Andrea Stolz; Dominika Labuz; Michael Schäfer; Michael Schaefer; Christoph Stein; Alexander Brack
Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils.
PLoS pathogens 2009;5(4):e1000362.
2009: Halina Machelska; Matthias Schroff; Detlef Oswald; Waltraud Binder; Nicolle Sitte; Shaaban A Mousa; Heike L Rittner; Alexander Brack; Dominika Labuz; Melanie Busch; Burghardt Wittig; Michael Schäfer; Christoph Stein
Peripheral non-viral MIDGE vector-driven delivery of beta-endorphin in inflammatory pain.
Molecular pain 2009;5():72.
2008: Christian Zöllner; Shaaban A Mousa; Astrid Klinger; Michael Förster; Michael Schäfer
Topical fentanyl in a randomized, double-blind study in patients with corneal damage.
The Clinical journal of pain 2008;24(8):690-6.
2008: Jochen Oeltjenbruns; Michael Schäfer
[Clinical significance of the placebo effect].
Der Anaesthesist 2008;57(5):447-63.
2008: Christian Zöllner; Shaaban A Mousa; Oliver Fischer; Heike L Rittner; Mohammed A Shaqura; Alexander Brack; Mehdi Shakibaei; Waltraud Binder; Florian Urban; Christoph Stein; Michael Schäfer
Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain.
The Journal of clinical investigation 2008;118(3):1065-73.
2008: Jörn Schäper; Raees Ahmed; Tobias Schäfer; Antje Elster; Fabian Enigk; Helmut Habazettl; Shaaban Mousa; Michael Schäfer; Martin Welte
Volume therapy with colloid solutions preserves intestinal microvascular perfusion in endotoxaemia.
Resuscitation 2008;76(1):120-8.
2007: Heike L Rittner; Christian Lux; Dominika Labuz; Shaaban A Mousa; Michael Schäfer; Christoph Stein; Alexander Brack
Neurokinin-1 receptor antagonists inhibit the recruitment of opioid-containing leukocytes and impair peripheral antinociception.
Anesthesiology 2007;107(6):1009-17.
2007: Shaaban A Mousa; Cheppudira P Bopaiah; Jan Richter; Reine S Yamdeu; Michael Schäfer
Inhibition of inflammatory pain by CRF at peripheral, spinal and supraspinal sites: involvement of areas coexpressing CRF receptors and opioid peptides.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(12):2530-42.
2007: Heike L Rittner; Dominika Labuz; Jan Richter; Alexander Brack; Michael Schäfer; Christoph Stein; Shaaban A Mousa
CXCR1/2 ligands induce p38 MAPK-dependent translocation and release of opioid peptides from primary granules in vitro and in vivo.
Brain, behavior, and immunity 2007;21(8):1021-32.
2007: Christian Zöllner; Michael Schäfer
[Remifentanil-based intraoperative anaesthesia and postoperative pain therapy. Is there an optimal treatment strategy?].
Der Anaesthesist 2007;56(10):1038-46.
2007: Steffen Schmidt; Christoph Bethge; Michael H Förster; Michael Schäfer
Enhanced postoperative sensitivity to painful pressure stimulation after intraoperative high dose remifentanil in patients without significant surgical site pain.
The Clinical journal of pain 2007;23(7):605-11.
2007: Dominika Labuz; Shaaban A Mousa; Michael Schäfer; Christoph Stein; Halina Machelska
Relative contribution of peripheral versus central opioid receptors to antinociception.
Brain research 2007;1160():30-8.
2007: Shaaban A Mousa; Rainer H Straub; Michael Schäfer; Christoph Stein
Beta-endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis.
Annals of the rheumatic diseases 2007;66(7):871-9.
2007: Nicolle Sitte; Melanie Busch; Shaaban A Mousa; Dominika Labuz; Heike L Rittner; Carmen Gore; Hans Krause; Christoph Stein; Michael Schäfer
Lymphocytes upregulate signal sequence-encoding proopiomelanocortin mRNA and beta-endorphin during painful inflammation in vivo.
Journal of neuroimmunology 2007;183(1-2):133-45.
2007: Shaaban A Mousa; Bopaiah P Cheppudira; Mohammed A Shaqura; Oliver Fischer; Julia Hofmann; Rainer Hellweg; Michael Schäfer
Nerve growth factor governs the enhanced ability of opioids to suppress inflammatory pain.
Brain : a journal of neurology 2007;130(Pt 2):502-13.
2007: Jeannette Endres-Becker; Paul A Heppenstall; Shaaban A Mousa; Dominika Labuz; Alexander Oksche; Michael Schäfer; Christoph Stein; Christian Zöllner
Mu-opioid receptor activation modulates transient receptor potential vanilloid 1 (TRPV1) currents in sensory neurons in a model of inflammatory pain.
Molecular pharmacology 2007;71(1):12-8.
2006: Heike L Rittner; Dominika Labuz; Michael Schaefer; Shaaban A Mousa; Stefan Schulz; Michael Schäfer; Christoph Stein; Alexander Brack
Pain control by CXCR2 ligands through Ca2+-regulated release of opioid peptides from polymorphonuclear cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2627-9.
2006: Wiebke Puehler; Heike L Rittner; Shaaban A Mousa; Alexander Brack; Hans Krause; Christoph Stein; Michael Schäfer
Interleukin-1 beta contributes to the upregulation of kappa opioid receptor mrna in dorsal root ganglia in response to peripheral inflammation.
Neuroscience 2006;141(2):989-98.
2006: Heike L Rittner; Shaaban A Mousa; Dominika Labuz; Karin Beschmann; Michael Schäfer; Christoph Stein; Alexander Brack
Selective local PMN recruitment by CXCL1 or CXCL2/3 injection does not cause inflammatory pain.
Journal of leukocyte biology 2006;79(5):1022-32.
2005: Jochen Oeltjenbruns; Michael Schäfer
[Potential applications and significance of peripheral opioid analgesia].
Schmerz (Berlin, Germany) 2005;19(5):447-52, 454-5.
2005: Alexander Brack; Heike L Rittner; Michael Schäfer
[Critical reevaluation of cyclooxygenase two inhibitors in perioperative pain therapy].
Der Anaesthesist 2005;54(10):1032-6, 1038.
2005: A N Beck; Michael Schäfer; Michael Werk; Maciej Pech; Gero Wieners; C Cho; Jens Ricke
Thermoablation of liver metastases: efficacy of temporary celiac plexus block.
Cardiovascular and interventional radiology 2005;28(4):454-8.
2005: Jochen Oeltjenbruns; Michael Schäfer
Peripheral opioid analgesia: clinical applications.
Current pain and headache reports 2005;9(1):36-44.
2004: Alexander Brack; Heike L Rittner; Halina Machelska; Kerstin Leder; Shaaban A Mousa; Michael Schäfer; Christoph Stein
Control of inflammatory pain by chemokine-mediated recruitment of opioid-containing polymorphonuclear cells.
Pain 2004;112(3):229-38.
2004: Jörn Adolphs; Diego K Schmidt; Ines Korsukewitz; Britta Kamin; Helmut Habazettl; Michael Schäfer; Martin Welte
Effects of thoracic epidural anaesthesia on intestinal microvascular perfusion in a rodent model of normotensive endotoxaemia.
Intensive care medicine 2004;30(11):2094-101.
2004: Nicole Hellwig; Tim D Plant; Wiebke Janson; Michael Schäfer; Günter Schultz; Michael Schaefer
TRPV1 acts as proton channel to induce acidification in nociceptive neurons.
The Journal of biological chemistry 2004;279(33):34553-61.
2004: Waltraud Binder; Shaaban A Mousa; Nicolle Sitte; Myriam Kaiser; Christoph Stein; Michael Schäfer
Sympathetic activation triggers endogenous opioid release and analgesia within peripheral inflamed tissue.
The European journal of neuroscience 2004;20(1):92-100.
2004: Alexander Brack; Dominika Labuz; Anu Schiltz; Heike L Rittner; Halina Machelska; Michael Schäfer; Regina Reszka; Christoph Stein
Tissue monocytes/macrophages in inflammation: hyperalgesia versus opioid-mediated peripheral antinociception.
Anesthesiology 2004;101(1):204-11.
2004: Halina Machelska; Alexander Brack; Shaaban A Mousa; Julia K Schopohl; Heike L Rittner; Michael Schäfer; Christoph Stein
Selectins and integrins but not platelet-endothelial cell adhesion molecule-1 regulate opioid inhibition of inflammatory pain.
British journal of pharmacology 2004;142(4):772-80.
2004: Alexander Brack; Heike L Rittner; Halina Machelska; Mohammed A Shaqura; Shaaban A Mousa; Dominika Labuz; Christian Zöllner; Michael Schäfer; Christoph Stein
Endogenous peripheral antinociception in early inflammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression.
Pain 2004;108(1-2):67-75.
2004: Alexander Brack; Heike L Rittner; Michael Schäfer
[Non-opioid analgesics for perioperative pain therapy. Risks and rational basis for use].
Der Anaesthesist 2004;53(3):263-80.
2004: Shaaban A Mousa; Mehdi Shakibaei; Nicolle Sitte; Michael Schäfer; Christoph Stein
Subcellular pathways of beta-endorphin synthesis, processing, and release from immunocytes in inflammatory pain.
Endocrinology 2004;145(3):1331-41.
2004: Mohammed A Shaqura; Christian Zöllner; Shaaban A Mousa; Christoph Stein; Michael Schäfer
Characterization of mu opioid receptor binding and G protein coupling in rat hypothalamus, spinal cord, and primary afferent neurons during inflammatory pain.
The Journal of pharmacology and experimental therapeutics 2004;308(2):712-8.
2004: Wiebke Puehler; Christian Zöllner; Alexander Brack; Mohammed A Shaqura; Hans Krause; Michael Schäfer; Christoph Stein
Rapid upregulation of mu opioid receptor mRNA in dorsal root ganglia in response to peripheral inflammation depends on neuronal conduction.
Neuroscience 2004;129(2):473-9.
2004: Alexander Brack; Heike L Rittner; Halina Machelska; Karin Beschmann; Nicolle Sitte; Michael Schäfer; Christoph Stein
Mobilization of opioid-containing polymorphonuclear cells by hematopoietic growth factors and influence on inflammatory pain.
Anesthesiology 2004;100(1):149-57.
2003: Shaaban A Mousa; Cheppudira P Bopaiah; Christoph Stein; Michael Schäfer
Involvement of corticotropin-releasing hormone receptor subtypes 1 and 2 in peripheral opioid-mediated inhibition of inflammatory pain.
Pain 2003;106(3):297-307.
2003: Jörn Adolphs; Diego K Schmidt; Shaaban A Mousa; Britta Kamin; Ines Korsukewitz; Helmut Habazettl; Michael Schäfer; Martin Welte
Thoracic epidural anesthesia attenuates hemorrhage-induced impairment of intestinal perfusion in rats.
Anesthesiology 2003;99(3):685-92.
2003: Halina Machelska; Julia K Schopohl; Shaaban A Mousa; Dominika Labuz; Michael Schäfer; Christoph Stein
Different mechanisms of intrinsic pain inhibition in early and late inflammation.
Journal of neuroimmunology 2003;141(1-2):30-9.
2003: Christoph Stein; Michael Schäfer; Halina Machelska
Attacking pain at its source: new perspectives on opioids.
Nature medicine 2003;9(8):1003-8.
2003: Michael Schäfer
Cytokines and peripheral analgesia.
Advances in experimental medicine and biology 2003;521():40-50.
2003: Thomas K Schmitt; Shaaban A Mousa; Alexander Brack; Diego K Schmidt; Heike L Rittner; Martin Welte; Michael Schäfer; Christoph Stein
Modulation of peripheral endogenous opioid analgesia by central afferent blockade.
Anesthesiology 2003;98(1):195-202.
2002: Shaaban A Mousa; Halina Machelska; Michael Schäfer; Christoph Stein
Immunohistochemical localization of endomorphin-1 and endomorphin-2 in immune cells and spinal cord in a model of inflammatory pain.
Journal of neuroimmunology 2002;126(1-2):5-15.
2001: Christoph Stein; Halina Machelska; Michael Schäfer
Peripheral analgesic and antiinflammatory effects of opioids.
Zeitschrift für Rheumatologie 2001;60(6):416-24.
2001: PJ Cabot; L Carter; Michael Schäfer; Christoph Stein
Methionine-enkephalin-and Dynorphin A-release from immune cells and control of inflammatory pain.
Pain 2001;93(3):207-12.
2001: Heike L Rittner; Alexander Brack; Halina Machelska; Shaaban A Mousa; M Bauer; Michael Schäfer; Christoph Stein
Opioid peptide-expressing leukocytes: identification, recruitment, and simultaneously increasing inhibition of inflammatory pain.
Anesthesiology 2001;95(2):500-8.
2001: Waltraud Binder; Halina Machelska; Shaaban A Mousa; T Schmitt; PJ Rivière; Jean-Louis Junien; Christoph Stein; Michael Schäfer
Analgesic and antiinflammatory effects of two novel kappa-opioid peptides.
Anesthesiology 2001;94(6):1034-44.
2001: Christoph Stein; Halina Machelska; Waltraud Binder; Michael Schäfer
Peripheral opioid analgesia.
Current opinion in pharmacology 2001;1(1):62-5.
2000: Shaaban A Mousa; Halina Machelska; Michael Schäfer; Christoph Stein
Co-expression of beta-endorphin with adhesion molecules in a model of inflammatory pain.
Journal of neuroimmunology 2000;108(1-2):160-70.
1999: Michael Schäfer
[Innovation and creativity. High salaries going to German researchers].
Der Anaesthesist 1999;48(8):558-9.
1998: Li Zhou; Q Zhang; Christoph Stein; Michael Schäfer
Contribution of opioid receptors on primary afferent versus sympathetic neurons to peripheral opioid analgesia.
The Journal of pharmacology and experimental therapeutics 1998;286(2):1000-6.
1998: Michael Schäfer; Li Zhou; Christoph Stein
Cholecystokinin inhibits peripheral opioid analgesia in inflamed tissue.
Neuroscience 1998;82(2):603-11.
1997: Michael Schäfer; Christoph Stein
[Postoperative pain. Medical and economic aspects].
Der Anaesthesist 1997;46 Suppl 2():S120-3.
1997: PJ Cabot; L Carter; Christian Gaiddon; Q Zhang; Michael Schäfer; Jean-Philippe Loeffler; Christoph Stein
Immune cell-derived beta-endorphin. Production, release, and control of inflammatory pain in rats.
The Journal of clinical investigation 1997;100(1):142-8.
1997: A Beyer; Michael Schäfer; Christoph Stein
Antinociceptive effects of dynorphin peptides in a model of inflammatory pain.
Pain 1997;70(2-3):141-7.
1997: Michael Schäfer; S A Mousa; Christoph Stein
Corticotropin-releasing factor in antinociception and inflammation.
European journal of pharmacology 1997;323(1):1-10.
1996: S A Mousa; Michael Schäfer; W M Mitchell; A H Hassan; Christoph Stein
Local upregulation of corticotropin-releasing hormone and interleukin-1 receptors in rats with painful hindlimb inflammation.
European journal of pharmacology 1996;311(2-3):221-31.
1995: Michael Schäfer; Y Imai; George R. Uhl; Christoph Stein
Inflammation enhances peripheral mu-opioid receptor-mediated analgesia, but not mu-opioid receptor transcription in dorsal root ganglia.
European journal of pharmacology 1995;279(2-3):165-9.
1994: Michael Schäfer; L Carter; Christoph Stein
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4219-23.