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Casper Schalkwijk

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Caatje Y le Poole; Casper G Schalkwijk; Tom Teerlink; Robert M Valentijn; Piet M Ter Wee; Frans J van Ittersum
Higher plasma levels of von Willebrand factor and C-reactive protein during a peritoneal dialysis regimen with less glucose and glucose degradation products.
Etto C Eringa; Alfons J H M Houben; Rick I Meijer; Casper G Schalkwijk; Erik H Serne; Yvo M Smulders; Coen D A Stehouwer; Victor W M van Hinsbergh
Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes.
Katrien H J Gaens; Coen D A Stehouwer; Casper G Schalkwijk
Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity.

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2013: Caatje Y le Poole; Casper G Schalkwijk; Tom Teerlink; Robert M Valentijn; Piet M Ter Wee; Frans J van Ittersum
Higher plasma levels of von Willebrand factor and C-reactive protein during a peritoneal dialysis regimen with less glucose and glucose degradation products.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2013;33(2):208-12.
2013: Etto C Eringa; Alfons J H M Houben; Rick I Meijer; Casper G Schalkwijk; Erik H Serne; Yvo M Smulders; Coen D A Stehouwer; Victor W M van Hinsbergh
Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes.
Reviews in endocrine & metabolic disorders 2013;14(1):39-48.
2013: Katrien H J Gaens; Coen D A Stehouwer; Casper G Schalkwijk
Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity.
Current opinion in lipidology 2013;24(1):4-11.
2013: Nick Wlazlo; Carla J H van der Kallen; Marleen M J van Greevenbroek; Bert Bravenboer; Isabel Ferreira; Edith J M Feskens; Eugene H J M Jansen; Casper G Schalkwijk; Coen D A Stehouwer
Iron metabolism is associated with adipocyte insulin resistance and plasma adiponectin: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) study.
Diabetes care 2013;36(2):309-15.
2013: Bas C T van Bussel; Marjo P H van de Waarenburg; Carla J H van der Kallen; Marleen M J van Greevenbroek; Isabel Ferreira; Edith J M Feskens; Ronald M A Henry; Coen D A Stehouwer; Casper G Schalkwijk
Multiple inflammatory biomarker detection in a prospective cohort study: a cross-validation between well-established single-biomarker techniques and an electrochemiluminescense-based multi-array platform.
PloS one 2013;8(3):e58576.
2013: Bart F J Heijnen; Ben J A Janssen; John J Mullins; Jelly Nelissen; Carine J Peutz-Kootstra; Casper G Schalkwijk; Jan W Cohen Tervaert; Gregorio E Fazzi; Helma van Essen; Harry A J Struijker Boudier
Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response.
PloS one 2013;8(2):e57815.
2012: Marleen M J van Greevenbroek; Carla J H van der Kallen; M C G J Brouwers; S Ghosh; Casper G Schalkwijk; C D A Stehouwer
Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistance.
The Journal of clinical endocrinology and metabolism 2012;97(12):4742-52.
2012: Nick Wlazlo; Carla J H van der Kallen; Marleen M J van Greevenbroek; Bert Bravenboer; Isabel Ferreira; Edith J M Feskens; Eugene J H M Jansen; Casper G Schalkwijk; Coen D A Stehouwer
Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: the CODAM study.
Metabolism: clinical and experimental 2012;61(12):1787-96.
2012: Nordin M J Hanssen; Maya S Huijberts; Giel Nijpels; Casper G Schalkwijk; Jacqueline M Dekker; Coen D A Stehouwer
Associations between the ankle-brachial index and cardiovascular and all-cause mortality are similar in individuals without and with type 2 diabetes: nineteen-year follow-up of a population-based cohort study.
Diabetes care 2012;35(8):1731-5.
2012: Bas C T van Bussel; Jacqueline M Dekker; Ronald M A Henry; Giel Nijpels; Casper G Schalkwijk; Coen D A Stehouwer
Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study.
Journal of hypertension 2012;30(4):744-52.
2012: Casper G Schalkwijk; Toshio Miyata
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics.
Amino acids 2012;42(4):1193-204.
2012: A K Berner; S Brockbank; O Brouwers; Michael Brownlee; L Colhoun; J W Curry; Ingeborg Klaassen; Carmel M McVicar; T Miyata; R Pringle; Casper G Schalkwijk; Reinier O Schlingemann; Alan Stitt
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology.
Diabetologia 2012;55(3):845-54.
2012: Katrien H J Gaens; Jan Willem M Greve; Marten H Hofker; Petra M G Niessen; Sander S Rensen; Johanne G Bloemen; Wim A Buurman; Cornelis H Dejong; Ann Driessen; Coen D A Stehouwer; Marcel G M Wolfs; Casper G Schalkwijk
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
Journal of hepatology 2012;56(3):647-55.
2012: Johanna W M Nin; Martin H Prins; Casper G Schalkwijk; Coen D A Stehouwer; Nish Chaturvedi; Isabel Ferreira; John H Fuller
Serum high-mobility group box-1 levels are positively associated with micro- and macroalbuminuria but not with cardiovascular disease in type 1 diabetes: the EURODIAB Prospective Complications Study.
European journal of endocrinology / European Federation of Endocrine Societies 2012;166(2):325-32.
2012: Marleen M J van Greevenbroek; Carla J H van der Kallen; Ellen E Blaak; Edith J M Feskens; Marjon Jacobs; Eugene H J M Jansen; Casper G Schalkwijk; Coen D A Stehouwer
Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study).
International journal of cardiology 2012;154(2):158-62.
2012: Duncan J Campbell; Alicia J Jenkins; Mary Jane Black; James F Kenny; Andrew E Newcomb; David L Prior; Casper G Schalkwijk; Jithendra B Somaratne; Michael Yii; Darren J Kelly
Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.
PloS one 2012;7(11):e49813.
2012: Alaa Alkhalaf; Henk J G Bilo; Reinold O B Gans; Klaas H Groenier; Peter Heeringa; Nanne Kleefstra; gerjan navis; Casper G Schalkwijk; Jean L Scheijen; Stephan J L Bakker
Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.
PloS one 2012;7(7):e40427.
2012: Jean L J M Scheijen; Coen D A Stehouwer; Marjo P H van de Waarenburg; Nordin M J Hanssen; Daisy M A E Jonkers; Casper G Schalkwijk
L(+) and D(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+) and D(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry.
Experimental diabetes research 2012;2012():234812.
2012: Caatje Y le Poole; Bengt Lindholm; Tom Teerlink; Robert M Valentijn; Frans J van Ittersum; Piet M Ter Wee; Casper G Schalkwijk
"NEPP" peritoneal dialysis regimen has beneficial effects on plasma CEL and 3-DG, but not pentosidine, CML, and MGO.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2012;32(1):45-54.
2011: Roel J J van de Laar; Colin A Boreham; Liam M Murray; Martin H Prins; Casper G Schalkwijk; Coen D A Stehouwer; Jos W R Twisk; Isabel Ferreira
Continuing smoking between adolescence and young adulthood is associated with higher arterial stiffness in young adults: the Northern Ireland Young Hearts Project.
Journal of hypertension 2011;29(11):2201-9.
2011: Lian Engelen; Isabel Ferreira; Peter Hovind; Hans-Henrik Parving; Frederik Persson; Peter Rossing; Coen D Stehouwer; Tom Teerlink; Casper G Schalkwijk
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(11):3573-7.
2011: Bas C van Bussel; Jos W Twisk; Michiel R de Boer; Isabel Ferreira; Ronald M A Henry; Casper G Schalkwijk; Fleur Schouten; Yvo M Smulders; Coen D Stehouwer
Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period.
Hypertension 2011;58(4):588-95.
2011: Inês Falcão-Pires; Cristina Gavina; Nazha Hamdani; Adelino F Leite-Moreira; Hans W M Niessen; Casper G Schalkwijk; Ger J M Stienen; Jolanda van der Velden; Loek van Heerebeek; Attila Borbély; Walter J Paulus
Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.
Circulation 2011;124(10):1151-9.
2011: Bas C T van Bussel; Martinette T Streppel; Jos W R Twisk; Isabel Ferreira; Edith J M Feskens; Ronald M A Henry; Casper G Schalkwijk; Yvo M Smulders; Coen D A Stehouwer
Fish consumption in healthy adults is associated with decreased circulating biomarkers of endothelial dysfunction and inflammation during a 6-year follow-up.
The Journal of nutrition 2011;141(9):1719-25.
2011: Marielle M Thewissen; Carla J H van der Kallen; Marleen M J van Greevenbroek; Edith J Feskens; Casper G Schalkwijk; Coen D Stehouwer; Ellen E Blaak; Jan W Cohen Tervaert; Jan G Damoiseaux; Adriaan M Duijvestijn; Isabel Ferreira
Abdominal fat mass is associated with adaptive immune activation: the CODAM Study.
Obesity (Silver Spring, Md.) 2011;19(8):1690-8.
2011: Marjon Jacobs; Eugene H J M Jansen; Casper G Schalkwijk; Isabel Ferreira; Edith J M Feskens; Carla J H van der Kallen; Marleen M J van Greevenbroek; Coen Stehouwer
The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study).
Metabolism: clinical and experimental 2011;60(7):969-75.
2011: Marleen M J van Greevenbroek; Marjon Jacobs; Carla J H van der Kallen; Vicky M M-J Vermeulen; Eugene H J M Jansen; Casper G Schalkwijk; Isabel Ferreira; Edith J M Feskens; Coen D A Stehouwer
The cross-sectional association between insulin resistance and circulating complement C3 is partly explained by plasma alanine aminotransferase, independent of central obesity and general inflammation (the CODAM study).
European journal of clinical investigation 2011;41(4):372-9.
2011: Lian Engelen; Søren S Lund; Isabel Ferreira; Lise Tarnow; Hans-Henrik Parving; Jørgen Gram; Kaj Winther; Oluf Pedersen; Tom Teerlink; Rob Barto; Coen D A Stehouwer; Allan A Vaag; Casper G Schalkwijk
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2011;164(3):371-9.
2011: Trijntje T Cnossen; Ulrich Gladziwa; Charles H Beerenhout; Karin Moret; Casper G Schalkwijk; Jean Scheijen; Jolanda van Amersfoort; Jos J van de Kerkhof; Jeroen P Kooman
The influence of bicarbonate/lactate-buffered PD fluids on N{ε}-(carboxyethyl)lysine and N{ε}-(carboxymethyl)lysine in peritoneal effluent.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2011;31(2):189-93.
2011: Johanna W Nin; Anders Jorsal; Isabel Ferreira; Casper G Schalkwijk; Martin H Prins; Hans-Henrik Parving; Lise Tarnow; Peter Rossing; Coen D Stehouwer
Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study.
Diabetes care 2011;34(2):442-7.
2011: Marjon Jacobs; Marleen M J van Greevenbroek; Carla J H van der Kallen; Isabel Ferreira; Ellen E Blaak; Edith J M Feskens; Eugène H J M Jansen; Casper G Schalkwijk; Coen D A Stehouwer
The association between the metabolic syndrome and peripheral, but not coronary, artery disease is partly mediated by endothelial dysfunction: the CODAM study.
European journal of clinical investigation 2011;41(2):167-75.
2011: Olaf Brouwers; Petra M Niessen; Isabel Ferreira; Toshio Miyata; Peter G Scheffer; Tom Teerlink; Patrick Schrauwen; Michael Brownlee; Coen D Stehouwer; Casper G Schalkwijk
Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats.
The Journal of biological chemistry 2011;286(2):1374-80.
2011: Duncan J Campbell; Alicia J Jenkins; Mary J Black; James F Kenny; Andrew E Newcomb; David L Prior; Casper G Schalkwijk; Jithendra B Somaratne; Michael Yii; Darren J Kelly
Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease.
Cardiovascular diabetology 2011;10():80.
2010: Erfan Nur; D P M Brandjes; John-John B Schnog; Hans-Martin Otten; Karin Fijnvandraat; Casper G Schalkwijk; Bart J Biemond
Plasma levels of advanced glycation end products are associated with haemolysis-related organ complications in sickle cell patients.
British journal of haematology 2010;151(1):62-9.
2010: Johanna W M Nin; Anders Jorsal; Isabel Ferreira; Casper G Schalkwijk; Martin H Prins; Hans-Henrik Parving; Lise Tarnow; Peter Rossing; Coen D A Stehouwer
Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study.
Diabetes 2010;59(8):2027-32.
2010: Frederik Persson; Peter Rossing; H Reinhard; T Juhl; C D A Stehouwer; Casper G Schalkwijk; Alexander Hessel Jan Danser; F Boomsma; E Frandsen; Hans-Henrik Parving
Optimal antiproteinuric dose of aliskiren in type 2 diabetes mellitus: a randomised crossover trial.
Diabetologia 2010;53(8):1576-80.
2010: O Brouwers; P M Niessen; G Haenen; T Miyata; Michael Brownlee; Coen D A Stehouwer; Jo De Mey; Casper G Schalkwijk
Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.
Diabetologia 2010;53(5):989-1000.
2010: Jasper W L Hartog; Ruud M van de Wal; Casper G Schalkwijk; Toshio Miyata; Wybren Jaarsma; H W Thijs Plokker; LM van Wijk; Andries J Smit; Dirk J van Veldhuisen; Adriaan A Voors
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
European journal of heart failure 2010;12(4):397-403.
2010: Lian Engelen; Isabel Ferreira; Katrien H J Gaens; Ronald M A Henry; Jacqueline M Dekker; Giel Nijpels; Robert J Heine; Leen M 't Hart; Marleen M J van Greevenbroek; Carla J H van der Kallen; Ellen E Blaak; Edith J M Feskens; Hugo ten Cate; Coen D A Stehouwer; Casper G Schalkwijk
The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies.
Journal of hypertension 2010;28(2):285-93.
2009: Katrien H J Gaens; Isabel Ferreira; Carla J H van der Kallen; Marleen M J van Greevenbroek; Ellen E Blaak; Edith J M Feskens; Jacqueline M Dekker; Giel Nijpels; Robert J Heine; Leen M 't Hart; Philip G de Groot; Coen D A Stehouwer; Casper G Schalkwijk
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels.
The Journal of clinical endocrinology and metabolism 2009;94(12):5174-80.
2009: Carla J H van der Kallen; Marleen M J van Greevenbroek; Coen D A Stehouwer; Casper G Schalkwijk
Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver?
Apoptosis : an international journal on programmed cell death 2009;14(12):1424-34.
2009: Frederik Persson; Peter Rossing; Henrik Reinhard; Tina Juhl; Coen D A Stehouwer; Casper G Schalkwijk; Alexander Hessel Jan Danser; Frans Boomsma; Erik Frandsen; Hans-Henrik Parving
Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria.
Diabetes care 2009;32(10):1873-9.
2009: Steven J R Meex; Daphna Weissglas-Volkov; Carla J H van der Kallen; Donna J Thuerauf; Marleen M J van Greevenbroek; Casper G Schalkwijk; Coen D A Stehouwer; Edith J M Feskens; Lonneke Heldens; Torik A Ayoubi; Marten H Hofker; Bradly G Wouters; Robert Francois Vlietinck; Janet S Sinsheimer; Marja-Riitta Taskinen; Johanna Kuusisto; Markku Laakso; Tjerk W A de Bruin; Päivi Pajukanta; Christopher C Glembotski
The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(9):1322-7.
2009: Lian Engelen; Isabel Ferreira; Olaf Brouwers; Ronald M A Henry; Jacqueline M Dekker; Giel Nijpels; Robert J Heine; Marleen M J van Greevenbroek; Carla J H van der Kallen; Ellen E Blaak; Edith J M Feskens; Hugo ten Cate; Coen D A Stehouwer; Casper G Schalkwijk
Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies.
Journal of hypertension 2009;27(7):1399-403.
2009: Ingeborg Klaassen; John M Hughes; Ilse M C Vogels; Casper G Schalkwijk; Cornelis J F Van Noorden; Reinier O Schlingemann
Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes.
Experimental eye research 2009;89(1):4-15.
2009: M Jacobs; Marleen M J van Greevenbroek; C J H van der Kallen; I Ferreira; Ellen E Blaak; Edith J M Feskens; E H J M Jansen; Casper G Schalkwijk; C D A Stehouwer
Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study.
European journal of clinical investigation 2009;39(6):437-44.
2009: Pauline A M Roest; Daniël G M Molin; Casper G Schalkwijk; Liesbeth van Iperen; Parri Wentzel; Ulf J Eriksson; Adriana C Gittenberger-De Groot
Specific local cardiovascular changes of Nepsilon-(carboxymethyl)lysine, vascular endothelial growth factor, and Smad2 in the developing embryos coincide with maternal diabetes-induced congenital heart defects.
Diabetes 2009;58(5):1222-8.
2009: Jean L J M Scheijen; Marjo P H van de Waarenburg; Coen D A Stehouwer; Casper G Schalkwijk
Measurement of pentosidine in human plasma protein by a single-column high-performance liquid chromatography method with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(7):610-4.
2008: Brian P Shapiro; Theophilus E Owan; Selma F Mohammed; Dan M Meyer; Lisa D. Mills; Casper G Schalkwijk; Margaret M Redfield
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
Circulation 2008;118(10):1002-10.
2008: Casper G Schalkwijk; O Brouwers; C D A Stehouwer
Modulation of insulin action by advanced glycation endproducts: a new player in the field.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(9):614-9.
2008: Jasper W L Hartog; Yoran M Hummel; Adriaan A Voors; Casper G Schalkwijk; Toshio Miyata; Roel M Huisman; Andries J Smit; Dirk J van Veldhuisen
Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients.
Journal of cardiac failure 2008;14(7):596-602.
2008: Steven J R Meex; Jana V van Vliet-Ostaptchouk; Carla J H van der Kallen; Marleen M J van Greevenbroek; Casper G Schalkwijk; Edith J M Feskens; Ellen E Blaak; Cisca Wijmenga; Marten H Hofker; Coen D A Stehouwer; Tjerk W A de Bruin
Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: association study in 2000 Dutch Caucasians.
Molecular genetics and metabolism 2008;94(3):352-5.
2008: Anne Sofie Astrup; Lise Tarnow; Lotte Pietraszek; Casper G Schalkwijk; Coen D A Stehouwer; Hans-Henrik Parving; Peter Rossing
Markers of endothelial dysfunction and inflammation in type 1 diabetic patients with or without diabetic nephropathy followed for 10 years: association with mortality and decline of glomerular filtration rate.
Diabetes care 2008;31(6):1170-6.
2008: Maya S P Huijberts; Nicolaas C Schaper; Casper G Schalkwijk
Advanced glycation end products and diabetic foot disease.
Diabetes/metabolism research and reviews 2008;24 Suppl 1():S19-24.
2008: A W van Deutekom; Hans W M Niessen; Casper G Schalkwijk; Robert J Heine; S Simsek
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(5):655-60.
2008: Søren S Lund; Lise Tarnow; Coen D A Stehouwer; Casper G Schalkwijk; Tom Teerlink; Jørgen Gram; Kaj Winther; Merete Frandsen; Ulla M Smidt; Oluf Pedersen; Hans-Henrik Parving; Allan Vaag
Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(5):631-41.
2008: Katrien H J Gaens; Carla J H van der Kallen; Marleen M J van Greevenbroek; Edith J Feskens; Coen D A Stehouwer; Casper G Schalkwijk
Receptor for advanced glycation end product polymorphisms and type 2 diabetes: the CODAM study.
Annals of the New York Academy of Sciences 2008;1126():162-5.
2008: Olaf Brouwers; Tom Teerlink; Jan van Bezu; Rob Barto; Coen D A Stehouwer; Casper G Schalkwijk
Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase.
Annals of the New York Academy of Sciences 2008;1126():231-4.
2008: Frederik Persson; Peter Rossing; Peter Hovind; Coen D A Stehouwer; Casper G Schalkwijk; Lise Tarnow; Hans-Henrik Parving
Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study.
Scandinavian journal of clinical and laboratory investigation 2008;68(8):731-8.
2008: Martijn C G J Brouwers; Jose Govers-Riemslag; Casper G Schalkwijk; Marleen M J van Greevenbroek; Carla J H van der Kallen; Otto Bekers; Marja Van Dieijen-Visser; Jaap Ten Oever; Monique A L Bilderbeek-Beckers; Tjerk W A de Bruin; Hugo Ten Cate; Coen D A Stehouwer
Plasma PAI-1 levels are independently related to fatty liver and hypertriglyceridemia in familial combined hyperlipidemia, involvement of apolipoprotein E.
Thrombosis research 2008;122(4):466-72.
2008: Loek van Heerebeek; Nazha Hamdani; Martin Louis Handoko; Ines Falcao-Pires; René J P Musters; Koba Kupreishvili; Alexander J J IJsselmuiden; Casper G Schalkwijk; Jean G F Bronzwaer; Michaela Diamant; Attila Borbély; Jolanda van der Velden; Ger J M Stienen; Gert-Jan Laarman; Hans W M Niessen; Walter J Paulus
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension.
Circulation 2008;117(1):43-51.
2007: Jasper W L Hartog; Adriaan A Voors; Casper G Schalkwijk; Jean Scheijen; Tom D J Smilde; Kevin Damman; Stephan J L Bakker; Andries J Smit; Dirk J van Veldhuisen
Clinical and prognostic value of advanced glycation end-products in chronic heart failure.
European heart journal 2007;28(23):2879-85.
2007: O Dotsenko; Nish Chaturvedi; Simon A McG Thom; Andrew R Wright; Jamil Mayet; Angela C Shore; Casper G Schalkwijk; Alun HUGHES
Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men.
Journal of thrombosis and haemostasis : JTH 2007;5(10):2036-42.
2007: Casper G Schalkwijk
Comment on "AGEs mediated expression and secretion of TNF alpha in rat retinal microglia" by Dr Wang et al.
Experimental eye research 2007;85(4):572-3; author reply 574.
2007: Janine Hartweg; Michael Gunter; Rafael Perera; Andrew Farmer; Carole A Cull; Casper G Schalkwijk; astrid kok; Harry Twaalfhoven; Rury Holman; Andrew Neil
Stability of soluble adhesion molecules, selectins, and C-reactive protein at various temperatures: implications for epidemiological and large-scale clinical studies.
Clinical chemistry 2007;53(10):1858-60.
2007: Roger K Schindhelm; Marjan Alssema; Peter G Scheffer; Michaela Diamant; Jacqueline M Dekker; Rob Barto; Giel Nijpels; Piet J Kostense; Robert J Heine; Casper G Schalkwijk; Tom Teerlink
Fasting and postprandial glycoxidative and lipoxidative stress are increased in women with type 2 diabetes.
Diabetes care 2007;30(7):1789-94.
2007: Steven J R Meex; Marleen M J van Greevenbroek; Torik A Ayoubi; Robert Francois Vlietinck; Jana V van Vliet-Ostaptchouk; Marten H Hofker; Vicky M M-J Vermeulen; Casper G Schalkwijk; Edith J M Feskens; Judith M Boer; Coen D A Stehouwer; Carla J H van der Kallen; Tjerk W A de Bruin
Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians.
The Journal of clinical endocrinology and metabolism 2007;92(7):2720-5.
2007: Nish Chaturvedi; Emma Coady; Jamil Mayet; Andrew R Wright; Angela C Shore; Sheila Byrd; Simon A McG Thom; Jaspal S Kooner; Casper G Schalkwijk; Alun HUGHES
Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease.
Atherosclerosis 2007;193(1):204-12.
2007: John M Hughes; Esther J Kuiper; Ingeborg Klaassen; Paul Canning; Alan Stitt; Jan van Bezu; Casper G Schalkwijk; Cornelis J F Van Noorden; Reinier O Schlingemann
Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina.
Diabetologia 2007;50(5):1089-98.
2007: Anna M E Bruynzeel; Mohamed A I Abou El Hassan; Casper G Schalkwijk; Johannes Berkhof; Aalt Bast; Hans W M Niessen; Wim J F van der Vijgh
Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice.
British journal of cancer 2007;96(6):937-43.
2007: Jolita Ciapaite; Stephan J L Bakker; Gerco Van Eikenhorst; Marijke J Wagner; Tom Teerlink; Casper G Schalkwijk; Mariann Fodor; D Margriet Ouwens; Michaela Diamant; Robert J Heine; Hans V Westerhoff; Klaas Krab
Functioning of oxidative phosphorylation in liver mitochondria of high-fat diet fed rats.
Biochimica et biophysica acta 2007;1772(3):307-16.
2007: Jolita Ciapaite; Jan van Bezu; Gerco Van Eikenhorst; Stephan J L Bakker; Tom Teerlink; Michaela Diamant; Robert J Heine; Klaas Krab; Hans V Westerhoff; Casper G Schalkwijk
Palmitate and oleate have distinct effects on the inflammatory phenotype of human endothelial cells.
Biochimica et biophysica acta 2007;1771(2):147-54.
2007: Casper G Schalkwijk; Bastiaan van Dam; Coen D A Stehouwer; Victor W M van Hinsbergh
Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells.
Clinical hemorheology and microcirculation 2007;37(1-2):179-84.
2006: Casper G Schalkwijk; Coen D A Stehouwer
PAI-1 inhibition in obesity and the metabolic syndrome: a promising therapeutic strategy.
Thrombosis and haemostasis 2006;96(6):698-9.
2006: Alexi Baidoshvili; P A J Krijnen; K Kupreishvili; C Ciurana; W Bleeker; Remco Nijmeijer; Cees A Visser; Frans C Visser; C J L M Meijer; Wim Stooker; León Eijsman; Victor W M van Hinsbergh; C Erik Hack; Hans W M Niessen; Casper G Schalkwijk
N(epsilon)-(carboxymethyl)lysine depositions in intramyocardial blood vessels in human and rat acute myocardial infarction: a predictor or reflection of infarction?
Arteriosclerosis, thrombosis, and vascular biology 2006;26(11):2497-503.
2006: Troels Krarup Hansen; Mari-Anne Gall; Lise Tarnow; Steffen Thiel; Coen D Stehouwer; Casper G Schalkwijk; Hans-Henrik Parving; Allan Flyvbjerg
Mannose-binding lectin and mortality in type 2 diabetes.
Archives of internal medicine 2006;166(18):2007-13.
2006: Jeroen van Heijst; Hans W M Niessen; René J P Musters; Victor W M van Hinsbergh; Klaas Hoekman; Casper G Schalkwijk
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
Cancer letters 2006;241(2):309-19.
2006: Majoie Hemelaar; Peter Kenemans; Casper G Schalkwijk; D D M Braat; Marius J van der Mooren
No increase in C-reactive protein levels during intranasal compared to oral hormone therapy in healthy post-menopausal women.
Human reproduction (Oxford, England) 2006;21(6):1635-42.
2006: Jeroen P Kooman; Casper G Schalkwijk; Constantijn J A M Konings
The increase in plasma levels of Nepsilon-(carboxymethyl)lysine during icodextrin treatment of peritoneal dialysis patients is not associated with increased plasma levels of vascular cell adhesion molecule-1.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2006;26(3):410-1.
2006: Sabita S Soedamah-Muthu; Nish Chaturvedi; Casper G Schalkwijk; Coen D A Stehouwer; Pertti Ebeling; John H Fuller
Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients.
Journal of diabetes and its complications 2006;20(3):188-95.
2006: Casper G Schalkwijk; Jan van Bezu; Roel C Van Der Schors; Koji Uchida; Coen D A Stehouwer; Victor W M van Hinsbergh
Heat-shock protein 27 is a major methylglyoxal-modified protein in endothelial cells.
FEBS letters 2006;580(6):1565-70.
2006: Frank Stam; Casper G Schalkwijk; Coen Van Guldener; Piet M ter Wee; Coen D A Stehouwer
Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(3):677-82.
2006: Mariska L M Lieuw-a-Fa; Casper G Schalkwijk; Marten Engelse; Victor W M van Hinsbergh
Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs.
Thrombosis and haemostasis 2006;95(2):320-8.
2006: Mohammad Zareie; Eelco D Keuning; Piet M ter Wee; Casper G Schalkwijk; Robert H J Beelen; Jacob Van Den Born
Improved biocompatibility of bicarbonate/lactate-buffered PDF is not related to pH.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(1):208-16.
2006: Casper G Schalkwijk; Nish Chaturvedi; Miranda T Schram; John H Fuller; Coen D A Stehouwer
Adiponectin is inversely associated with renal function in type 1 diabetic patients.
The Journal of clinical endocrinology and metabolism 2006;91(1):129-35.
2006: Mareille Gritters; Muriel P C Grooteman; Marianne schoorl; Marianne Schoorl; Piet C M Bartels; Peter G Scheffer; Tom Teerlink; Casper G Schalkwijk; Marieke D Spreeuwenberg; Menso J Nubé
Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(1):153-9.
2005: Mohammad Zareie; Geert Jan Tangelder; Piet M ter Wee; Liesbeth Hekking; Anton A van Lambalgen; Eelco D Keuning; Inge L Schadee-Eestermans; Casper G Schalkwijk; Robert H J Beelen; Jacob Van Den Born
Beneficial effects of aminoguanidine on peritoneal microcirculation and tissue remodelling in a rat model of PD.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(12):2783-92.
2005: Muriel P C Grooteman; Mareille Gritters; Inge M P M J Wauters; Casper G Schalkwijk; Frank Stam; Jos W R Twisk; Piet M ter Wee; Menso J Nubé
Patient characteristics rather than the type of dialyser predict the variability of endothelial derived surface molecules in chronic haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(12):2751-8.
2005: Constantijn J A M Konings; Casper G Schalkwijk; Frank van der Sande; Karel M L Leunissen; Jeroen P Kooman
Influence of icodextrin on plasma and dialysate levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2005;25(6):591-5.
2005: Elbert-Jaap I Schipper; Antoinette C Bolte; Casper G Schalkwijk; Herman P van Geijn; Gustaaf A Dekker
TNF-receptor levels in preeclampsia--results of a longitudinal study in high-risk women.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2005;18(5):283-7.
2005: Prabath W B Nanayakkara; Tom Teerlink; Coen D A Stehouwer; Daud Allajar; Annemieke M W Spijkerman; Casper G Schalkwijk; Piet M ter Wee; Coen Van Guldener
Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure.
Kidney international 2005;68(5):2230-6.
2005: Majoie Hemelaar; Marius J van der Mooren; W Marchien van Baal; Casper G Schalkwijk; Peter Kenemans; Coen D A Stehouwer
Effects of transdermal and oral postmenopausal hormone therapy on vascular function: a randomized, placebo-controlled study in healthy postmenopausal women.
Menopause (New York, N.Y.) 2005;12(5):526-35.
2005: Bart C Kuenen; Giuseppe Giaccone; Rita Ruijter; astrid kok; Casper G Schalkwijk; Klaas Hoekman; HERBERT PINEDO
Dose-finding study of the multitargeted tyrosine kinase inhibitor SU6668 in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6240-6.
2005: Casper G Schalkwijk; Coen D A Stehouwer
Vascular complications in diabetes mellitus: the role of endothelial dysfunction.
Clinical science (London, England : 1979) 2005;109(2):143-59.
2005: Miranda T Schram; Casper G Schalkwijk; Aart H Bootsma; John H Fuller; Nish Chaturvedi; Coen D A Stehouwer
Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study.
Hypertension 2005;46(1):232-7.
2005: Mohammad Zareie; An S De Vriese; Liesbeth Hekking; Piet M ter Wee; Casper G Schalkwijk; Bas A J Driesprong; Inge L Schadee-Eestermans; Robert H J Beelen; Norbert Lameire; Jacob Van Den Born
Immunopathological changes in a uraemic rat model for peritoneal dialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(7):1350-61.
2005: Jeroen van Heijst; Hans W M Niessen; Klaas Hoekman; Casper G Schalkwijk
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine.
Annals of the New York Academy of Sciences 2005;1043():725-33.
2005: Casper G Schalkwijk; Piet M ter Wee; Coen D A Stehouwer
Plasma levels of AGE peptides in type 1 diabetic patients are associated with serum creatinine and not with albumin excretion rate: possible role of AGE peptide-associated endothelial dysfunction.
Annals of the New York Academy of Sciences 2005;1043():662-70.
2005: Miranda T Schram; Frans J van Ittersum; A M E Spoelstra-De Man; R A J M van Dijk; Casper G Schalkwijk; Richard G IJzerman; Jos W R Twisk; C D A Stehouwer
Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals: effects on albumin excretion, endothelial function and inflammation in a double-blind, randomized clinical trial.
Journal of human hypertension 2005;19(6):429-37.
2005: Miranda T Schram; Nish Chaturvedi; Casper G Schalkwijk; John H Fuller; C D A Stehouwer
Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes--the EURODIAB Prospective Complications Study.
Diabetologia 2005;48(2):370-8.
2005: Anne van Tellingen; Casper G Schalkwijk; Tom Teerlink; Rob Barto; Muriel P C Grooteman; Tjeerd van der Ploeg; Piet M ter Wee; Menso J Nubé
Influence of different haemodialysis modalities on AGE peptide levels: intradialytic versus long-term results.
Nephron. Clinical practice 2005;100(1):c1-7.
2005: J De Jager; Adriaan Kooy; Philippe Lehert; Daniel Bets; Michiel G Wulffelé; Tom Teerlink; Peter G Scheffer; Casper G Schalkwijk; A J M Donker; C D A Stehouwer
Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
Journal of internal medicine 2005;257(1):100-9.
2004: Tatjana E Vogelvang; Velja Mijatovic; Peter Kenemans; Casper G Schalkwijk; Marius J van der Mooren
Effect of HMR 3339, a novel selective estrogen receptor modulator, on C-reactive protein levels in healthy postmenopausal women.
The American journal of cardiology 2004;94(9):1205-8.
2004: Casper G Schalkwijk; Coen D A Stehouwer; Victor W M van Hinsbergh
Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification.
Diabetes/metabolism research and reviews 2004;20(5):369-82.
2004: Siska Mortier; Dirk Faict; Casper G Schalkwijk; Norbert H Lameire; An S De Vriese
Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane.
Kidney international 2004;66(3):1257-65.
2004: Dirkje W Sommeijer; Aida Beganovic; Casper G Schalkwijk; Hanneke Ploegmakers; Chris M van der Loos; Benien E van Aken; Hugo ten Cate; Allard C van der Wal
More fibrosis and thrombotic complications but similar expression patterns of markers for coagulation and inflammation in symptomatic plaques from DM2 patients.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2004;52(9):1141-9.
2004: Tom Teerlink; Rob Barto; Herman J Ten Brink; Casper G Schalkwijk
Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry.
Clinical chemistry 2004;50(7):1222-8.
2004: Troels Krarup Hansen; Lise Tarnow; Steffen Thiel; Rudi Steffensen; Coen D Stehouwer; Casper G Schalkwijk; Hans-Henrik Parving; Allan Flyvbjerg
Association between mannose-binding lectin and vascular complications in type 1 diabetes.
Diabetes 2004;53(6):1570-6.
2004: Alexi Baidoshvili; Hans W M Niessen; Wim Stooker; Rien A J M Huybregts; C Erik Hack; Jan A Rauwerda; Chris J L M Meijer; León Eijsman; Victor W M van Hinsbergh; Casper G Schalkwijk
N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels.
Atherosclerosis 2004;174(2):287-92.
2004: Jos van de Kerkhof; Casper G Schalkwijk; Constantijn J A M Konings; Emile C Cheriex; Frank van der Sande; Peter G Scheffer; Piet M ter Wee; Karel M L Leunissen; Jeroen P Kooman
Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine and vascular cell adhesion molecule-1 (VCAM-1) in relation to peritoneal glucose prescription and residual renal function; a study in peritoneal dialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(4):910-6.
2004: Angelique G A Welten; Mohammad Zareie; Jacob Van Den Born; Piet M ter Wee; Casper G Schalkwijk; Bas A J Driesprong; Frederik P J Mul; Peter L Hordijk; Robert H J Beelen; Liesbeth Hekking
In vitro and in vivo models for peritonitis demonstrate unchanged neutrophil migration after exposure to dialysis fluids.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(4):831-9.
2004: Casper G Schalkwijk; Alexi Baidoshvili; Coen D A Stehouwer; Victor W M van Hinsbergh; Hans W M Niessen
Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody.
Biochimica et biophysica acta 2004;1636(2-3):82-9.
2004: Mariska L M Lieuw-a-Fa; Victor W M van Hinsbergh; Tom Teerlink; Rob Barto; Jos W R Twisk; Coen D A Stehouwer; Casper G Schalkwijk
Increased levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(3):631-6.
2003: M Bourajjaj; C D A Stehouwer; Victor W M van Hinsbergh; Casper G Schalkwijk
Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus.
Biochemical Society transactions 2003;31(Pt 6):1400-2.
2003: Mohammad Zareie; Liesbeth Hekking; Angelique G A Welten; Bas A J Driesprong; Inge L Schadee-Eestermans; Dirk Faict; Anne Leyssens; Casper G Schalkwijk; Robert H J Beelen; Piet M ter Wee; Jacob Van Den Born
Contribution of lactate buffer, glucose and glucose degradation products to peritoneal injury in vivo.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(12):2629-37.
2003: Miranda T Schram; Frank Stam; Renate T de Jongh; Greetje De Vries; R A J M van Dijk; Erik H Serné; Deva Lampe; Prabath W B Nanayakkara; Maarten E Tushuizen; Peter G Scheffer; Casper G Schalkwijk; Adriaan M Kamper; Coen D A Stehouwer
The effect of calcium dobesilate on vascular endothelial function, blood pressure, and markers of oxidation in obese male smokers: a placebo-controlled randomised clinical trial.
Atherosclerosis 2003;170(1):59-72.
2003: Mohamed A I Abou El Hassan; Hendrik Verheul; Anita S Jorna; Casper G Schalkwijk; J van Bezu; Wim J F van der Vijgh; Aalt Bast
The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitro.
British journal of cancer 2003;89(2):357-62.
2003: Miranda T Schram; Nish Chaturvedi; Casper G Schalkwijk; Francesco Giorgino; Pertti Ebeling; John H Fuller; Coen D Stehouwer
Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study.
Diabetes care 2003;26(7):2165-73.
2003: Erik J J Duschek; C D A Stehouwer; Gerdien W de Valk-de Roo; Casper G Schalkwijk; J Lambert; JAN COEN NETELENBOS
Raloxifene, conjugated oestrogen and endothelial function in postmenopausal women.
Journal of internal medicine 2003;254(1):85-94.
2003: Mariska L M Lieuw-a-Fa; Casper G Schalkwijk; Victor W M van Hinsbergh
Distinct accumulation patterns of soluble forms of E-selectin, VCAM-1 and ICAM-1 upon infusion of TNFalpha in tumor patients.
Thrombosis and haemostasis 2003;89(6):1052-7.
2003: Jonathan Krakoff; Tohru Funahashi; Coen D A Stehouwer; Casper G Schalkwijk; Sachiyo Tanaka; Yuji Matsuzawa; Sayuko Kobes; P Antonio Tataranni; Robert L Hanson; William C Knowler; Robert S Lindsay
Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian.
Diabetes care 2003;26(6):1745-51.
2003: Angelique G A Welten; Casper G Schalkwijk; Piet M ter Wee; Sybren Meijer; Jacob Van Den Born; Robert J H Beelen
Single exposure of mesothelial cells to glucose degradation products (GDPs) yields early advanced glycation end-products (AGEs) and a proinflammatory response.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2003;23(3):213-21.
2003: Frank Stam; Coen Van Guldener; Casper G Schalkwijk; Piet M ter Wee; A J M Donker; Coen D A Stehouwer
Impaired renal function is associated with markers of endothelial dysfunction and increased inflammatory activity.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(5):892-8.
2003: E G J Vermeulen; Jan A Rauwerda; M van den Berg; SC de Jong; Casper G Schalkwijk; Jos W R Twisk; C D A Stehouwer
Homocysteine-lowering treatment with folic acid plus vitamin B6 lowers urinary albumin excretion but not plasma markers of endothelial function or C-reactive protein: further analysis of secondary end-points of a randomized clinical trial.
European journal of clinical investigation 2003;33(3):209-15.
2003: Bastiaan van Dam; Victor W M van Hinsbergh; Coen D A Stehouwer; Amanda Versteilen; Henk Dekker; Rien Buytenhek; Hans M G Princen; Casper G Schalkwijk
Vitamin E inhibits lipid peroxidation-induced adhesion molecule expression in endothelial cells and decreases soluble cell adhesion molecules in healthy subjects.
Cardiovascular research 2003;57(2):563-71.
2002: Nish Chaturvedi; Casper G Schalkwijk; Heidemarie Abrahamian; John H Fuller; Coen D A Stehouwer
Circulating and urinary transforming growth factor beta1, Amadori albumin, and complications of type 1 diabetes: the EURODIAB prospective complications study.
Diabetes care 2002;25(12):2320-7.
2002: Marinka S Post; Marius J van der Mooren; C D A Stehouwer; W Marchien van Baal; Velja Mijatovic; Casper G Schalkwijk; Peter Kenemans
Effects of transdermal and oral oestrogen replacement therapy on C-reactive protein levels in postmenopausal women: a randomised, placebo-controlled trial.
Thrombosis and haemostasis 2002;88(4):605-10.
2002: Helen M Colhoun; Casper G Schalkwijk; Michael B Rubens; Coen D A Stehouwer
C-reactive protein in type 1 diabetes and its relationship to coronary artery calcification.
Diabetes care 2002;25(10):1813-7.
2002: JN Patel; A Jager; Casper G Schalkwijk; Roger Corder; Julie A Douthwaite; John S Yudkin; Simon W Coppack; C D A Stehouwer
Effects of tumour necrosis factor-alpha in the human forearm: blood flow and endothelin-1 release.
Clinical science (London, England : 1979) 2002;103(4):409-15.
2002: Casper G Schalkwijk; Nish Chaturvedi; H Twaafhoven; Victor W M van Hinsbergh; C D A Stehouwer
Amadori-albumin correlates with microvascular complications and precedes nephropathy in type 1 diabetic patients.
European journal of clinical investigation 2002;32(7):500-6.
2002: Casper G Schalkwijk; Mariska L M Lieuw-a-Fa; Victor W M van Hinsbergh; Coen D A Stehouwer
Pathophysiological role of Amadori-glycated proteins in diabetic microangiopathy.
Seminars in vascular medicine 2002;2(2):191-7.
2002: Christian Weyer; John S Yudkin; Coen D A Stehouwer; Casper G Schalkwijk; Richard E Pratley; P Antonio Tataranni
Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians.
Atherosclerosis 2002;161(1):233-42.
2002: Nicole Verzijl; Jeroen DeGroot; Zaken Chaya Ben; Orit Brau-Benjamin; Alice Maroudas; Ruud A Bank; Joseph Mizrahi; Casper G Schalkwijk; Suzanne R Thorpe; John W Baynes; J W J Bijlsma; Floris P J G Lafeber; Johan teKoppele
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Arthritis and rheumatism 2002;46(1):114-23.
2001: Dennis C W Poland; Casper G Schalkwijk; Coen D A Stehouwer; Carolien A M Koeleman; Bert Van het Hof; Willem Van Dijk
Increased alpha3-fucosylation of alpha1-acid glycoprotein in Type I diabetic patients is related to vascular function.
Glycoconjugate journal 2001;18(3):261-8.
2001: N Posthuma; Piet M ter Wee; H Niessen; A J M Donker; Henri A Verbrugh; Casper G Schalkwijk
Amadori albumin and advanced glycation end-product formation in peritoneal dialysis using icodextrin.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2001;21(1):43-51.
2000: Casper G Schalkwijk; Piet M ter Wee; Tom Teerlink
Reduced 1,2-dicarbonyl compounds in bicarbonate/lactate-buffered peritoneal dialysis (PD) fluids and PD fluids based on glucose polymers or amino acids.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2000;20(6):796-8.
2000: Casper G Schalkwijk; RA Smulders; J Lambert; A J M Donker; Coen D A Stehouwer
ACE-inhibition modulates some endothelial functions in healthy subjects and in normotensive type 1 diabetic patients.
European journal of clinical investigation 2000;30(10):853-60.
2000: Erik J Giltay; Johanna C M Fonk; B M von Blomberg; Hemmo Drexhage; Casper G Schalkwijk; Louis J G Gooren
In vivo effects of sex steroids on lymphocyte responsiveness and immunoglobulin levels in humans.
The Journal of clinical endocrinology and metabolism 2000;85(4):1648-57.
1999: Casper G Schalkwijk; N Ligtvoet; H Twaalfhoven; Agnes Jager; Harriet G Blaauwgeers; Reinier O Schlingemann; Lise Tarnow; Hans-Henrik Parving; Coen D A Stehouwer; Victor W M van Hinsbergh
Amadori albumin in type 1 diabetic patients: correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries.
Diabetes 1999;48(12):2446-53.
1999: W Marchien van Baal; Jef J Emeis; Peter Kenemans; H Kessel; ER Peters-Muller; Casper G Schalkwijk; Marius J van der Mooren; Coen D A Stehouwer
Short-term hormone replacement therapy: reduced plasma levels of soluble adhesion molecules.
European journal of clinical investigation 1999;29(11):913-21.
1999: Gerdien W de Valk-de Roo; Coen D A Stehouwer; J Lambert; Casper G Schalkwijk; Marius J van der Mooren; Cornelis Kluft; JAN COEN NETELENBOS
Plasma homocysteine is weakly correlated with plasma endothelin and von Willebrand factor but not with endothelium-dependent vasodilatation in healthy postmenopausal women.
Clinical chemistry 1999;45(8 Pt 1):1200-5.
1999: Casper G Schalkwijk; N Posthuma; Herman J Ten Brink; Piet M ter Wee; Tom Teerlink
Induction of 1,2-dicarbonyl compounds, intermediates in the formation of advanced glycation end-products, during heat-sterilization of glucose-based peritoneal dialysis fluids.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1999;19(4):325-33.
1999: W Marchien van Baal; Peter Kenemans; Jef J Emeis; Casper G Schalkwijk; Velja Mijatovic; Marius J van der Mooren; Ulrich Vischer; Coen D A Stehouwer
Long-term effects of combined hormone replacement therapy on markers of endothelial function and inflammatory activity in healthy postmenopausal women.
Fertility and sterility 1999;71(4):663-70.
1999: Casper G Schalkwijk; Dennis C W Poland; Willem Van Dijk; astrid kok; Jef J Emeis; Angelika M Dräger; A Doni; Victor W M van Hinsbergh; Coen D A Stehouwer
Plasma concentration of C-reactive protein is increased in type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation.
Diabetologia 1999;42(3):351-7.
1998: Casper G Schalkwijk; Mario Vermeer; Coen D A Stehouwer; Johan teKoppele; H M Princen; Victor W M van Hinsbergh
Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein.
Biochimica et biophysica acta 1998;1394(2-3):187-98.
1998: RA Smulders; Coen D A Stehouwer; Casper G Schalkwijk; A J M Donker; Victor W M van Hinsbergh; Johan teKoppele
Distinct associations of HbA1c and the urinary excretion of pentosidine, an advanced glycosylation end-product, with markers of endothelial function in insulin-dependent diabetes mellitus.
Thrombosis and haemostasis 1998;80(1):52-7.