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Joost Schanstra

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Julien Gonzalez; Julie Klein; Joost P Schanstra; Jean-Loup Bascands; Cécile Caubet; Romain Dissard; Marie Essig; Bénédicte Buffin-Meyer
[Renal urinary shear stress: a novel actor in nephropathies].
Mathieu Miravète; Christiane Pecher; Bernard Pipy; Joost P Schanstra; Cécile Caubet; Romain Dissard; Julien Gonzalez; Julie Klein; Muriel Mercier-Bonin; Jean-Loup Bascands; Bénédicte Buffin-Meyer
Renal tubular fluid shear stress facilitates monocyte activation toward inflammatory macrophages.
Julie Klein; Panagiotis Moulos; Robert Stevens; Jean-Loup Bascands; Bénédicte Buffin-Meyer; Audrey Casemayou; Rana Chaaya; Aristidis Charonis; Myriem Fernandez; Simon Jupp; Joost P Schanstra
The KUPKB: a novel Web application to access multiomics data on kidney disease.

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2013: Julien Gonzalez; Julie Klein; Joost P Schanstra; Jean-Loup Bascands; Cécile Caubet; Romain Dissard; Marie Essig; Bénédicte Buffin-Meyer
[Renal urinary shear stress: a novel actor in nephropathies].
Médecine sciences : M/S 2013;29(3):279-85.
2012: Mathieu Miravète; Christiane Pecher; Bernard Pipy; Joost P Schanstra; Cécile Caubet; Romain Dissard; Julien Gonzalez; Julie Klein; Muriel Mercier-Bonin; Jean-Loup Bascands; Bénédicte Buffin-Meyer
Renal tubular fluid shear stress facilitates monocyte activation toward inflammatory macrophages.
American journal of physiology. Renal physiology 2012;302(11):F1409-17.
2012: Julie Klein; Panagiotis Moulos; Robert Stevens; Jean-Loup Bascands; Bénédicte Buffin-Meyer; Audrey Casemayou; Rana Chaaya; Aristidis Charonis; Myriem Fernandez; Simon Jupp; Joost P Schanstra
The KUPKB: a novel Web application to access multiomics data on kidney disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(5):2145-53.
2012: Flavio Bandin; Jean-Loup Bascands; Benjamin Breuil; Stéphane Decramer; Harald Mischak; Justyna Siwy; Joost P Schanstra
Urinary proteome analysis at 5-year followup of patients with nonoperated ureteropelvic junction obstruction suggests ongoing kidney remodeling.
The Journal of urology 2012;187(3):1006-11.
2011: Aristidis Charonis; Theo Luider; Marc Baumann; Joost P Schanstra
Is the time ripe for kidney tissue proteomics?
Proteomics. Clinical applications 2011;5(5-6):215-21.
2011: Julie Klein; Julien Gonzalez; Mathieu Miravete; Cécile Caubet; Rana Chaaya; Stéphane Decramer; Flavio Bandin; Jean-Loup Bascands; Bénédicte Buffin-Meyer; Joost P Schanstra
Congenital ureteropelvic junction obstruction: human disease and animal models.
International journal of experimental pathology 2011;92(3):168-92.
2011: Chloé Rancoule; Jean-Philippe Pradère; Julien Gonzalez; Julie Klein; Philippe Valet; Jean-Loup Bascands; Joost P Schanstra; Jean Sébastien Saulnier-Blache
Lysophosphatidic acid-1-receptor targeting agents for fibrosis.
Expert opinion on investigational drugs 2011;20(5):657-67.
2011: Mathieu Miravète; Julie Klein; Aurèle Besse-Patin; Julien Gonzalez; Christiane Pecher; Jean-Loup Bascands; Muriel Mercier-Bonin; Joost P Schanstra; Bénédicte Buffin-Meyer
Renal tubular fluid shear stress promotes endothelial cell activation.
Biochemical and biophysical research communications 2011;407(4):813-7.
2011: Harald Mischak; Joost P Schanstra
CE-MS in biomarker discovery, validation, and clinical application.
Proteomics. Clinical applications 2011;5(1-2):9-23.
2011: Julie Klein; Panagiotis Kavvadas; Niki Prakoura; Fani Karagianni; Joost P Schanstra; Jean-Loup Bascands; Aristidis Charonis
Renal fibrosis: insight from proteomics in animal models and human disease.
Proteomics 2011;11(4):805-15.
2011: Rana Chaaya; Chiara Alfarano; Céline Guilbeau-Frugier; Christelle Coatrieux; Anne-Sylvie Kesteman; Angelo Parini; Nassim Fares; Michelle Gue; Joost P Schanstra; Jean-Loup Bascands
Pargyline reduces renal damage associated with ischaemia-reperfusion and cyclosporin.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(2):489-98.
2011: Julie Klein; Mathieu Miravete; Bénédicte Buffin-Meyer; Joost P Schanstra; Jean-Loup Bascands
[Tubulo-interstitial fibrosis: an emerging major health problem].
Médecine sciences : M/S 2011;27(1):55-61.
2010: Harald Mischak; Christian Delles; Julie Klein; Joost P Schanstra
Urinary proteomics based on capillary electrophoresis-coupled mass spectrometry in kidney disease: discovery and validation of biomarkers, and clinical application.
Advances in chronic kidney disease 2010;17(6):493-506.
2010: Jens Drube; Petra Zürbig; Eric Schiffer; Esther Lau; Benno Ure; Sylvia Glüer; Martin Kirschstein; Lars Pape; Stéphane Decramer; Jean-Loup Bascands; Joost P Schanstra; Mischak Harald; Jochen H H Ehrich
Urinary proteome analysis identifies infants but not older children requiring pyeloplasty.
Pediatric nephrology (Berlin, Germany) 2010;25(9):1673-8.
2010: Julie Klein; Julien Gonzalez; Stéphane Decramer; Flavio Bandin; Eric Neau; David J Salant; Peter Heeringa; João B Pesquero; Joost P Schanstra; Jean-Loup Bascands
Blockade of the kinin B1 receptor ameloriates glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2010;21(7):1157-64.
2010: Franck Molina; Matthias Dehmer; Paul Perco; Armin Graber; Mark Girolami; Goce Spasovski; Joost P Schanstra; Antonia Vlahou
Systems biology: opening new avenues in clinical research.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(4):1015-8.
2010: Anna F Dominiczak; Stefan Herget-Rosenthal; Christian Delles; Danilo Fliser; Isabelle Fournier; Armin Graber; Mark Girolami; Elaine Holmes; Florian Lang; Franck Molina; Jeremy Nicholson; Giuseppe Remuzzi; Peter Rossing; Karl Lenhard Rudolph; Olaf Wolkenhauer; Ioannis Xenarios; Roman Zubarev; Dimitry Zubov; Antonia Vlahou; Joost P Schanstra
Systems biology to battle vascular disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(4):1019-22.
2010: Mohammed Dakna; Keith Harris; Alexandros Kalousis; Sebastien Carpentier; Walter Kolch; Joost P Schanstra; Marion Haubitz; Antonia Vlahou; Harald Mischak; Mark Girolami
Addressing the challenge of defining valid proteomic biomarkers and classifiers.
BMC bioinformatics 2010;11():594.
2010: Cécile Caubet; Chrystelle Lacroix; Stéphane Decramer; Jens Drube; Jochen H H Ehrich; Mischak Harald; Jean-Loup Bascands; Joost P Schanstra
Advances in urinary proteome analysis and biomarker discovery in pediatric renal disease.
Pediatric nephrology (Berlin, Germany) 2010;25(1):27-35.
2009: Julien Gonzalez; Julie Klein; Sharmila D Chauhan; Eric Neau; Denis Calise; Caroline Nevoit; Rana Chaaya; Mathieu Miravete; Christine Delage; Jean-Loup Bascands; Joost P Schanstra; Bénédicte Buffin-Meyer
Delayed treatment with plasminogen activator inhibitor-1 decoys reduces tubulointerstitial fibrosis.
Experimental biology and medicine (Maywood, N.J.) 2009;234(12):1511-8.
2009: Mischak Harald; Joshua Coon; Jan Novak; Eva M Weissinger; Joost P Schanstra; Anna F Dominiczak
Capillary electrophoresis-mass spectrometry as a powerful tool in biomarker discovery and clinical diagnosis: an update of recent developments.
Mass spectrometry reviews 2009;28(5):703-24.
2009: Jean-Loup Bascands; Magdalena Bachvarova; Eric Neau; Joost P Schanstra; Dimcho Bachvarov
Molecular determinants of LPS-induced acute renal inflammation: Implication of the kinin B1 receptor.
Biochemical and biophysical research communications 2009;386(2):407-12.
2009: Petra Zürbig; Stéphane Decramer; Mohammed Dakna; Justyna Jantos; David M Good; Joshua J Coon; Flavio Bandin; Mischak Harald; Jean-Loup Bascands; Joost P Schanstra
The human urinary proteome reveals high similarity between kidney aging and chronic kidney disease.
Proteomics 2009;9(8):2108-17.
2009: Jochen Metzger; Joost P Schanstra; Mischak Harald
Capillary electrophoresis-mass spectrometry in urinary proteome analysis: current applications and future developments.
Analytical and bioanalytical chemistry 2009;393(5):1431-42.
2008: Nicolle Kraenkel; Rajesh G Katare; Mauro Siragusa; Luciola S Barcelos; Paola Campagnolo; Giuseppe Mangialardi; Orazio Fortunato; Gaia Spinetti; Nguyen Tran; Kai Zacharowski; Wojciech Wojakowski; Iwona Mroz; Andrew Herman; Jocelyn E Manning Fox; Patrick E MacDonald; Joost P Schanstra; Jean-Loup Bascands; Raimondo Ascione; Gianni Angelini; Costanza Emanueli; Paolo Madeddu
Role of kinin B2 receptor signaling in the recruitment of circulating progenitor cells with neovascularization potential.
Circulation research 2008;103(11):1335-43.
2008: Stéphane Decramer; Anne Gonzalez de Peredo; Benjamin Breuil; Mischak Harald; Bernard Monsarrat; Jean-Loup Bascands; Joost P Schanstra
Urine in clinical proteomics.
Molecular & cellular proteomics : MCP 2008;7(10):1850-62.
2008: Jean Philippe Pradère; Julien Gonzalez; Julie Klein; Philippe Valet; Sandra Grès; David Salant; Jean-Loup Bascands; Jean Sébastien Saulnier-Blache; Joost P Schanstra
Lysophosphatidic acid and renal fibrosis.
Biochimica et biophysica acta 2008;1781(9):582-7.
2008: Kasper Rossing; Mischak Harald; Peter Rossing; Joost P Schanstra; Alex Wiseman; David M Maahs
The urinary proteome in diabetes and diabetes-associated complications: New ways to assess disease progression and evaluate therapy.
Proteomics. Clinical applications 2008;2(7-8):997-1007.
2008: Marcelo A Mori; Ronaldo C Araújo; Felipe C G Reis; Daniela G Sgai; Raphael G Fonseca; Carlos C Barros; Vanessa F Merino; Mariana Passadore; Ana M Barbosa; Bernard Ferrari; Pierre Carayon; Charlles H M Castro; Suma I Shimuta; Jacqueline Luz; Jean-Loup Bascands; Joost P Schanstra; Patrick C Even; Suzana M Oliveira; Michael Bader; João B Pesquero
Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.
Diabetes 2008;57(6):1491-500.
2008: Stephane Decramer; Stefan Wittke; Mischak Harald; Jean-Loup Bascands; Petra Zürbig; Joost P Schanstra
Identification of urinary biomarkers by proteomics in newborns: use in obstructive nephropathy.
Contributions to nephrology 2008;160():127-41.
2007: Jean Philippe Pradère; Julie Klein; Sandra Grès; Charlotte Guigné; Eric Neau; Philippe Valet; Denis Calise; Jerold Chun; Jean-Loup Bascands; Jean Sébastien Saulnier-Blache; Joost P Schanstra
LPA1 receptor activation promotes renal interstitial fibrosis.
Journal of the American Society of Nephrology : JASN 2007;18(12):3110-8.
2007: David Good; Visith Thongboonkerd; Jan Novak; Jean-Loup Bascands; Joost P Schanstra; Joshua J Coon; Anna Dominiczak; Mischak Harald
Body fluid proteomics for biomarker discovery: lessons from the past hold the key to success in the future.
Journal of proteome research 2007;6(12):4549-55.
2007: Stéphane Decramer; Jean-Loup Bascands; Joost P Schanstra
Non-invasive markers of ureteropelvic junction obstruction.
World journal of urology 2007;25(5):457-65.
2007: Jean-Loup Bascands; J Klein; Joost P Schanstra
A nest in renal fibrosis?
Kidney international 2007;72(3):242-4.
2007: Joost P Schanstra; Magdalena Bachvarova; Eric Neau; Jean-Loup Bascands; Dimcho Bachvarov
Gene expression profiling in the remnant kidney model of wild type and kinin B1 and B2 receptor knockout mice.
Kidney international 2007;72(4):442-54.
2007: Edson L Santos; Rosana I Reis; Ronaldo G Silva; Suma I Shimuta; Christiane Pecher; Jean-Loup Bascands; Joost P Schanstra; Laerte Oliveira; Michael Bader; Antonio C M Paiva; Claudio Costa-Neto; João B Pesquero
Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene.
Regulatory peptides 2007;141(1-3):159-67.
2007: Rosana I Reis; Edson L Santos; João B Pesquero; Laerte Oliveira; Joost P Schanstra; Jean-Loup Bascands; Christiane Pecher; Antonio C M Paiva; Claudio Costa-Neto
Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction.
Regulatory peptides 2007;140(1-2):32-6.
2007: Stéphane Decramer; Olivier Parant; Sandrine Beaufils; Séverine Clauin; Cécile Guillou; Sylvie Kessler; Jacqueline Aziza; Flavio Bandin; Joost P Schanstra; Christine Bellanné-Chantelot
Anomalies of the TCF2 gene are the main cause of fetal bilateral hyperechogenic kidneys.
Journal of the American Society of Nephrology : JASN 2007;18(3):923-33.
2006: Ronaldo C Araújo; Marcelo A Mori; Vanessa F Merino; Jean-Loup Bascands; Joost P Schanstra; Ricardo L Zollner; Conceição A Villela; Clovis R Nakaie; Antonio C M Paiva; Jorge L Pesquero; Michael Bader; João B Pesquero
Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function.
Biological chemistry 2006;387(4):431-6.
2006: Stéphane Decramer; Stefan Wittke; Mischak Harald; Petra Zürbig; Michael Walden; François Bouissou; Jean-Loup Bascands; Joost P Schanstra
Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis.
Nature medicine 2006;12(4):398-400.
2006: Dimcho Bachvarov; Magdalena Bachvarova; Rainelli Koumangaye; Julie Klein; João B Pesquero; Eric Neau; Michael Bader; Joost P Schanstra; Jean-Loup Bascands
Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes.
Biological chemistry 2006;387(1):15-22.
2005: Jean-Loup Bascands; Joost P Schanstra
Obstructive nephropathy: insights from genetically engineered animals.
Kidney international 2005;68(3):925-37.
2005: Maria Martha Campos; Brice Ongali; Hudson De Souza Buck; Joost P Schanstra; Jean-Pierre Girolami; Jean-Guy Chabot; Réjean Couture
Expression and distribution of kinin B1 receptor in the rat brain and alterations induced by diabetes in the model of streptozotocin.
Synapse (New York, N.Y.) 2005;57(1):29-37.
2005: Vanessa F Merino; Jose Silva Junior; Ronaldo C Araújo; Maria Christina W Avellar; Jean-Loup Bascands; Joost P Schanstra; Antonio C M Paiva; Michael Bader; João B Pesquero
Molecular structure and transcriptional regulation by nuclear factor-kappaB of the mouse kinin B1 receptor gene.
Biological chemistry 2005;386(6):515-22.
2005: Johan Duchene; Sharmila D Chauhan; Frédéric Lopez; Christiane Pecher; Jean-Pierre Estève; Jean-Pierre Girolami; Jean-Loup Bascands; Joost P Schanstra
Direct protein-protein interaction between PLCgamma1 and the bradykinin B2 receptor--importance of growth conditions.
Biochemical and biophysical research communications 2005;326(4):894-900.
2004: Jean-Loup Bascands; Joost P Schanstra
Bradykinin and renal fibrosis: have we ACE'd it?
Journal of the American Society of Nephrology : JASN 2004;15(9):2504-6.
2003: Jean-Loup Bascands; Joost P Schanstra; Réjean Couture; Jean-Pierre Girolami
[Bradykinin receptors: towards new pathophysiological roles].
Médecine sciences : M/S 2003;19(11):1093-100.
2003: Joost P Schanstra; Jean-Loup Bascands
[Experimental ureteral obstruction and knockout animals].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 2003;10(10):903-10.
2003: Joost P Schanstra; Johan Duchene; Françoise Praddaude; Patrick Bruneval; Ivan Tack; Jacques Chevalier; Jean-Pierre Girolami; Jean-Loup Bascands
Decreased renal NO excretion and reduced glomerular tuft area in mice lacking the bradykinin B2 receptor.
American journal of physiology. Heart and circulatory physiology 2003;284(6):H1904-8.
2003: Joost P Schanstra; Johan Duchene; Laurence Desmond; Eric Neau; Denis Calise; Serge Estaque; Jean-Pierre Girolami; Jean-Loup Bascands
The protective effect of angiotensin converting enzyme inhibition in experimental renal fibrosis in mice is not mediated by bradykinin B2 receptor activation.
Thrombosis and haemostasis 2003;89(4):735-40.
2002: Heloisa A Baptista; Maria Christina W Avellar; Ronaldo C Araujo; Jorge L Pesquero; Joost P Schanstra; Jean-Loup Bascands; Jean P Esteve; Antonio C M Paiva; Michael Bader; João B Pesquero
Transcriptional regulation of the rat bradykinin B2 receptor gene: identification of a silencer element.
Molecular pharmacology 2002;62(6):1344-55.
2002: Johan Duchene; Joost P Schanstra; Christiane Pecher; Anne Pizard; Christiane Susini; Jean-Pierre Esteve; Jean-Loup Bascands; Jean-Pierre Girolami
A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation.
The Journal of biological chemistry 2002;277(43):40375-83.
2002: Joost P Schanstra; Eric Neau; Pascale Drogoz; Miguel A Arevalo Gomez; José Lopez-Novoa; Denis Calise; Christiane Pecher; Michael Bader; Jean-Pierre Girolami; Jean-Loup Bascands
In vivo bradykinin B2 receptor activation reduces renal fibrosis.
The Journal of clinical investigation 2002;110(3):371-9.
2002: Céline Alric; Christiane Pecher; Eric Cellier; Joost P Schanstra; Bruno Poirier; Jacques Chevalier; Jean-Loup Bascands; Jean-Pierre Girolami
Inhibition of IGF-I-induced Erk 1 and 2 activation and mitogenesis in mesangial cells by bradykinin.
Kidney international 2002;62(2):412-21.
2002: Eric Cellier; Johan Duchêne; Christiane Pécher; Céline Alric; Jean-Loup Bascands; Joost P Schanstra; Jean-Pierre Girolami
B2 receptor activation reduces Erk1 and Erk2 phosphorylation induced by insulin-like growth factor-1, platelet-derived growth factor-BB, and high glucose in rat isolated glomeruli.
Canadian journal of physiology and pharmacology 2002;80(4):341-5.
2002: Marilyne Mage; Christiane Pécher; Eric Neau; Eric Cellier; Marina L Dos Reiss; Joost P Schanstra; Réjean Couture; Jean-Loup Bascands; Jean-Pierre Girolami
Induction of B1 receptors in streptozotocin diabetic rats: possible involvement in the control of hyperglycemia-induced glomerular Erk 1 and 2 phosphorylation.
Canadian journal of physiology and pharmacology 2002;80(4):328-33.
2002: Maria E Marin-Castano; Joost P Schanstra; Eric Neau; Françoise Praddaude; Christiane Pecher; Jean-Louis Ader; Jean-Pierre Girolami; Jean-Loup Bascands
Induction of functional bradykinin b(1)-receptors in normotensive rats and mice under chronic Angiotensin-converting enzyme inhibitor treatment.
Circulation 2002;105(5):627-32.
2002: Johan Duchêne; Joost P Schanstra; Eric Cellier; Jean-Loup Bascands; Jean-Pierre Girolami
[30 years: Happy birthday, GPCR. The bradykinin B2 receptor: an alternative and antiproliferative pathway].
Néphrologie 2002;23(1):39-41.
2000: Joost P Schanstra; Maria E Marin-Castano; Françoise Praddaude; Ivan Tack; Jean-Louis Ader; Jean-Pierre Girolami; Jean-Loup Bascands; B Jeunier
Bradykinin B(1) receptor-mediated changes in renal hemodynamics during endotoxin-induced inflammation.
Journal of the American Society of Nephrology : JASN 2000;11(7):1208-15.
2000: Céline Alric; Christiane Pecher; Joost P Schanstra; Jean-Loup Bascands; Jean-Pierre Girolami
Bradykinin-induced inhibition of cell proliferation and tyrosine kinase activity in rat mesangial cells.
International journal of molecular medicine 2000;5(1):85-93.
1999: Joost P Schanstra; Maria E Marin-Castano; Céline Alric; João B Pesquero; M Claire; Jean-Pierre Girolami; Jean-Loup Bascands
Homologous and heterologous induction of the human bradykinin B1-receptor and B1-receptor localisation along the rat nephron.
Immunopharmacology 1999;45(1-3):29-34.
1999: Céline Alric; Christiane Pecher; Ivan Tack; Joost P Schanstra; Jean-Loup Bascands; Jean-Pierre Girolami
Inhibition of cGMP accumulation in mesangial cells by bradykinin and tyrosine kinase inhibitors.
International journal of molecular medicine 1999;4(5):557-64.
1999: Joost P Schanstra; Céline Alric; Maria E Marin-Castano; Jean-Pierre Girolami; Jean-Loup Bascands
Renal bradykinin receptors: localisation, transduction pathways and molecular basis for a possible pathological role (review).
International journal of molecular medicine 1999;3(2):185-91.
1998: Maria E Marin-Castano; Joost P Schanstra; Françoise Praddaude; João B Pesquero; Jean-Louis Ader; Jean-Pierre Girolami; Jean-Loup Bascands
Differential induction of functional B1-bradykinin receptors along the rat nephron in endotoxin induced inflammation.
Kidney international 1998;54(6):1888-98.
1998: Joost P Schanstra; E Bataillé; Maria E Marin-Castano; Y Barascud; C Hirtz; João B Pesquero; Christiane Pecher; F Gauthier; Jean-Pierre Girolami; Jean-Loup Bascands
The B1-agonist [des-Arg10]-kallidin activates transcription factor NF-kappaB and induces homologous upregulation of the bradykinin B1-receptor in cultured human lung fibroblasts.
The Journal of clinical investigation 1998;101(10):2080-91.
1998: Maria E Marin-Castano; Joost P Schanstra; C Hirtz; João B Pesquero; Christiane Pecher; Jean-Pierre Girolami; Jean-Loup Bascands
B2 kinin receptor upregulation by cAMP is associated with BK-induced PGE2 production in rat mesangial cells.
The American journal of physiology 1998;274(3 Pt 2):F532-40.