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Matthew Scharff

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Piers E M Patten; Kanti R Rai; Sergio Roa; Matthew D Scharff; Joy (Xiao-Jie) Yan; Lu Zhang; Emilia Albesiano; Steven Allen; Jacqueline Barrientos; Charles C Chu; Rajendra N Damle; Dorothy Kim; Jonathan E Kolitz; Thomas MacCarthy; Amanda R Magli; Patricia K Mongini; Nicholas Chiorazzi
IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions.
Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Sergio Roa
AIDing antibody diversity by error-prone mismatch repair.
Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Johanna M M van Oers; Chunfang Zhao; Elena Avdievich; Sergio Roa
The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.

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All Publications

2012: Piers E M Patten; Kanti R Rai; Sergio Roa; Matthew D Scharff; Joy (Xiao-Jie) Yan; Lu Zhang; Emilia Albesiano; Steven Allen; Jacqueline Barrientos; Charles C Chu; Rajendra N Damle; Dorothy Kim; Jonathan E Kolitz; Thomas MacCarthy; Amanda R Magli; Patricia K Mongini; Nicholas Chiorazzi
IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions.
Blood 2012;120(24):4802-11.
2012: Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Sergio Roa
AIDing antibody diversity by error-prone mismatch repair.
Seminars in immunology 2012;24(4):293-300.
2012: Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Johanna M M van Oers; Chunfang Zhao; Elena Avdievich; Sergio Roa
The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.
The Journal of experimental medicine 2012;209(4):671-8.
2012: Sabrina A Volpi; Uwe Werling; Britta Will; Sanjukta Chatterjee; Winfried Edelman; Ann J Feeney; Rabih Hassan; Harry Hou; Zhongliang Ju; Sergio Roa; Matthew D Scharff; Ulrich Steidl; Jiyoti Verma-Gaur; Barbara K Birshtein
Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(6):2556-66.
2012: Jakub Sroubek; Susan Buhl; Jordan Chinai; Yamini Krishnan; Matthew D Scharff; Thomas V McDonald
The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel.
Journal of immunological methods 2012;375(1-2):215-22.
2011: Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Sergio Roa
Mismatch-mediated error prone repair at the immunoglobulin genes.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2011;65(8):529-36.
2011: Avanish Varshney; Xiao Bo Wang; Emily Cook; Kaushik Dutta; Matthew D Scharff; Michael J Goger; Bettina C Fries
Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against staphylococcal enterotoxin B-induced lethal shock.
The Journal of biological chemistry 2011;286(11):9737-47.
2011: Linda B. Baughn; Aviv Bergman; Manxia Fan; Susan L Kalis; Thomas MacCarthy; Lirong Wei; Matthew D Scharff
Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.
mBio 2011;2(5):.
2011: Carlo Calissano; Steven Allen; Rajendra N Damle; Igor M Dozmorov; Claire Emson; Gregory Hayes; Marc K Hellerstein; Ivana Ivanovic; Matthew Kaufman; Jonathan E Kolitz; Wentian Li; Sonia Marsilio; Elizabeth J Murphy; Kanti R Rai; Sergio Roa; Matthew D Scharff; Cristina Sison; Joy (Xiao-Jie) Yan; Sophia Yancopoulos; Nicholas Chiorazzi
Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells.
Molecular medicine (Cambridge, Mass.) 2011;17(11-12):1374-82.
2010: Jonathan U Peled; Rani S Sellers; Maria Iglesias de Ussel; Dong-Mi Shin; Cristina Montagna; Chunfang Zhao; Ziqiang Li; Winfried Edelmann; Herbert C Morse; Matthew D Scharff
Msh6 protects mature B cells from lymphoma by preserving genomic stability.
The American journal of pathology 2010;177(5):2597-608.
2010: Nareen Abboud; Siu-Kei Chow; Carolyn Saylor; Alena Janda; Jeffery V Ravetch; Matthew D Scharff; Arturo Casadevall
A requirement for FcγR in antibody-mediated bacterial toxin neutralization.
The Journal of experimental medicine 2010;207(11):2395-405.
2010: Johanna M M van Oers; Sergio Roa; Uwe Werling; Yiyong Liu; Jochen Genschel; Harry Hou; Rani S Sellers; Paul Modrich; Matthew D Scharff; Winfried Edelmann
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(30):13384-9.
2010: Jonathan U Peled; J Jessica Yu; Jeganathan Venkatesh; Enguang Bi; Bing-Bing Ding; Melissa Krupski-Downs; Rita Shaknovich; Piotr Sicinski; Betty Diamond; Matthew D Scharff; B Hilda Ye
Requirement for cyclin D3 in germinal center formation and function.
Cell research 2010;20(6):631-46.
2010: Shaliny Ramachandran; Richard Chahwan; Rajeev M Nepal; Darina Frieder; Stephanie Panier; Sergio Roa; Ahmad Zaheen; Daniel Durocher; Matthew D Scharff; Alberto Martin
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(2):809-14.
2010: Sergio Roa; Ziqiang Li; Jonathan U Peled; Chunfang Zhao; Winfried Edelmann; Matthew D Scharff
MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites.
PloS one 2010;5(6):e11182.
2009: Maria Iglesias de Ussel; Jiri Zavadil; Matthew D Scharff
Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro.
Journal of immunological methods 2009;350(1-2):71-8.
2009: Thomas MacCarthy; Susan L Kalis; Sergio Roa; Phuong Pham; Myron F Goodman; Matthew D Scharff; Aviv Bergman
V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8629-34.
2009: Fei Li Kuang; Zhonghui Luo; Matthew D Scharff
H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(13):5288-93.
2009: Thomas MacCarthy; Sergio Roa; Matthew D Scharff; Aviv Bergman
SHMTool: a webserver for comparative analysis of somatic hypermutation datasets.
DNA repair 2009;8(1):137-41.
2008: Sergio Roa; Elena Avdievich; Jonathan U Peled; Thomas MacCarthy; Uwe Werling; Fei Li Kuang; Rui Kan; Chunfang Zhao; Aviv Bergman; Paula E Cohen; Winfried Edelmann; Matthew D Scharff
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16248-53.
2008: Sergio Roa; Fei Li Kuang; Matthew D Scharff
Does antisense make sense of AID targeting?
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3661-2.
2008: Jonathan U Peled; Fei Li Kuang; Maria Iglesias de Ussel; Sergio Roa; Susan L Kalis; Myron F Goodman; Matthew D Scharff
The biochemistry of somatic hypermutation.
Annual review of immunology 2008;26():481-511.
2008: Iglika Batova; Czeslawa Kowal; Rena May; Matthew D Scharff; Betty Diamond
Human recombinant Fab fragments with sub-nanomolar affinities for acetylated histones.
Journal of immunological methods 2008;329(1-2):1-10.
2007: Diana Ronai; Maria Iglesias de Ussel; Manxia Fan; Ziqiang Li; Alberto Martin; Matthew D Scharff
Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation.
The Journal of experimental medicine 2007;204(1):181-90.
2007: Myron F Goodman; Matthew D Scharff; Floyd E Romesberg
AID-initiated purposeful mutations in immunoglobulin genes.
Advances in immunology 2007;94():127-55.
2007: Ziqiang Li; Zhonghui Luo; Diana Ronai; Fei Li Kuang; Jonathan U Peled; Maria Iglesias de Ussel; Matthew D Scharff
Targeting AID to the Ig genes.
Advances in experimental medicine and biology 2007;596():93-109.
2006: Maria Iglesias de Ussel; Manxia Fan; Ziqiang Li; Alberto Martin; Matthew D Scharff
Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells.
Journal of immunological methods 2006;316(1-2):59-66.
2006: Ziqiang Li; Jonathan U Peled; Chunfang Zhao; Anton Svetlanov; Diana Ronai; Paula E Cohen; Matthew D Scharff
A role for Mlh3 in somatic hypermutation.
DNA repair 2006;5(6):675-82.
2006: Ziqiang Li; Chunfang Zhao; Maria Iglesias de Ussel; Zhanna Polonskaya; Min Zhuang; Guozhe Yang; Zhonghui Luo; Winfried Edelmann; Matthew D Scharff
The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus.
Immunity 2006;24(4):393-403.
2006: Reuven Laskov; Nir Berger; Matthew D Scharff; Marshall S Horwitz
Tumor necrosis factor-alpha and CD40L modulate cell surface morphology and induce aggregation in Ramos Burkitt's lymphoma cells.
Leukemia & lymphoma 2006;47(3):507-19.
2005: Diana Ronai; Maria Iglesias de Ussel; Manxia Fan; Marc J Shulman; Matthew D Scharff
Complex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11829-34.
2005: Mani Larijani; Darina Frieder; Timothy M Sonbuchner; Ronda Bransteitter; Myron F Goodman; Eric E Bouhassira; Matthew D Scharff; Alberto Martin
Methylation protects cytidines from AID-mediated deamination.
Molecular immunology 2005;42(5):599-604.
2005: Myron F Goodman; Matthew D Scharff
Identifying protein-protein interactions in somatic hypermutation.
The Journal of experimental medicine 2005;201(4):493-6.
2005: Marcela Torres; Rena May; Matthew D Scharff; Arturo Casadevall
Variable-region-identical antibodies differing in isotype demonstrate differences in fine specificity and idiotype.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):2132-42.
2004: Ziqiang Li; Zhonghui Luo; Matthew D Scharff
Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15428-33.
2004: Zhonghui Luo; Diana Ronai; Matthew D Scharff
The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies.
The Journal of allergy and clinical immunology 2004;114(4):726-35; quiz 736.
2004: Ziqiang Li; Stefan J Scherer; Diana Ronai; Maria Iglesias de Ussel; Jonathan U Peled; Philip D Bardwell; Min Zhuang; KyeRyoung Lee; Alberto Martin; Winfried Edelmann; Matthew D Scharff
Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification.
The Journal of experimental medicine 2004;200(1):47-59.
2004: Philip D Bardwell; Caroline J Woo; Kaichun Wei; Ziqiang Li; Alberto Martin; Stephen Z Sack; Tchaiko Parris; Winfried Edelmann; Matthew D Scharff
Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.
Nature immunology 2004;5(2):224-9.
2004: Ziqiang Li; Caroline J Woo; Maria Iglesias de Ussel; Diana Ronai; Matthew D Scharff
The generation of antibody diversity through somatic hypermutation and class switch recombination.
Genes & development 2004;18(1):1-11.
2003: Rena J May; David O Beenhouwer; Matthew D Scharff
Antibodies to keyhole limpet hemocyanin cross-react with an epitope on the polysaccharide capsule of Cryptococcus neoformans and other carbohydrates: implications for vaccine development.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4905-12.
2003: Alberto Martin; Ziqiang Li; Diana P Lin; Philip D Bardwell; Maria Iglesias de Ussel; Winfried Edelmann; Matthew D Scharff
Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination.
The Journal of experimental medicine 2003;198(8):1171-8.
2003: Caroline J Woo; Alberto Martin; Matthew D Scharff
Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin.
Immunity 2003;19(4):479-89.
2003: Ziqiang Li; Caroline J Woo; Matthew D Scharff
Mutations in AID and UNG extend the function of AID.
Nature immunology 2003;4(10):945-6.
2003: Ronda Bransteitter; Phuong Pham; Matthew D Scharff; Myron F Goodman
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4102-7.
2003: Philip D Bardwell; Alberto Martin; Edmund Wong; Ziqiang Li; Winfried Edelmann; Matthew D Scharff
Cutting edge: the G-U mismatch glycosylase methyl-CpG binding domain 4 is dispensable for somatic hypermutation and class switch recombination.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1620-4.
2002: David O Beenhouwer; Rena J May; Philippe Valadon; Matthew D Scharff
High affinity mimotope of the polysaccharide capsule of Cryptococcus neoformans identified from an evolutionary phage peptide library.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):6992-9.
2002: Alberto Martin; Matthew D Scharff
Somatic hypermutation of the AID transgene in B and non-B cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12304-8.
2002: Xianyuan Song; Scott Shapiro; David Goldman; Arturo Casadevall; Matthew D Scharff; Sunhee C Lee
Fcgamma receptor I- and III-mediated macrophage inflammatory protein 1alpha induction in primary human and murine microglia.
Infection and immunity 2002;70(9):5177-84.
2002: Alberto Martin; Matthew D Scharff
AID and mismatch repair in antibody diversification.
Nature reviews. Immunology 2002;2(8):605-14.
2002: Philip D Bardwell; Alberto Martin; Matthew D Scharff
Mutation detection of immunoglobulin V-regions by DHPLC.
Journal of immunological methods 2002;266(1-2):165-73.
2002: Scott Shapiro; David O Beenhouwer; Marta Feldmesser; Carlos Taborda; Michael C Carroll; Arturo Casadevall; Matthew D Scharff
Immunoglobulin G monoclonal antibodies to Cryptococcus neoformans protect mice deficient in complement component C3.
Infection and immunity 2002;70(5):2598-604.
2002: Alberto Martin; Philip D Bardwell; Caroline J Woo; Manxia Fan; Marc J Shulman; Matthew D Scharff
Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas.
Nature 2002;415(6873):802-6.
2001: David O Beenhouwer; S Shapiro; Marta Feldmesser; Arturo Casadevall; Matthew D Scharff
Both Th1 and Th2 cytokines affect the ability of monoclonal antibodies to protect mice against Cryptococcus neoformans.
Infection and immunity 2001;69(10):6445-55.
2001: W Zhang; Philip D Bardwell; Caroline J Woo; V Poltoratsky; Matthew D Scharff; Alberto Martin
Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line.
International immunology 2001;13(9):1175-84.
2001: A Martin; Matthew D Scharff
Immunology. Antibody alterations.
Nature 2001;412(6850):870-1.
2001: S Z Sack; Philip D Bardwell; Matthew D Scharff
Testing the reverse transcriptase model of somatic mutation.
Molecular immunology 2001;38(4):303-11.
2001: V Poltoratsky; Caroline J Woo; Brigette Tippin; Alberto Martin; Myron F Goodman; Matthew D Scharff
Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7976-81.
2000: lionel zuckier; E Z Berkowitz; R J Sattenberg; QH Zhao; H F Deng; Matthew D Scharff
Influence of affinity and antigen density on antibody localization in a modifiable tumor targeting model.
Cancer research 2000;60(24):7008-13.
2000: V Poltoratsky; Myron F Goodman; Matthew D Scharff
Error-prone candidates vie for somatic mutation.
The Journal of experimental medicine 2000;192(10):F27-30.
2000: M Wiesendanger; Burkhard Kneitz; Winfried Edelmann; Matthew D Scharff
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern.
The Journal of experimental medicine 2000;191(3):579-84.
1999: G Nussbaum; S Anandasabapathy; J Mukherjee; M Fan; Arturo Casadevall; Matthew D Scharff
Molecular and idiotypic analyses of the antibody response to Cryptococcus neoformans glucuronoxylomannan-protein conjugate vaccine in autoimmune and nonautoimmune mice.
Infection and immunity 1999;67(9):4469-76.
1998: lionel zuckier; C J Chang; Matthew D Scharff; S L Morrison
Chimeric human-mouse IgG antibodies with shuffled constant region exons demonstrate that multiple domains contribute to in vivo half-life.
Cancer research 1998;58(17):3905-8.
1998: M Wiesendanger; Matthew D Scharff; Winfried Edelmann
Somatic hypermutation, transcription, and DNA mismatch repair.
Cell 1998;94(4):415-8.
1998: Philippe Valadon; G Nussbaum; J Oh; Matthew D Scharff
Aspects of antigen mimicry revealed by immunization with a peptide mimetic of Cryptococcus neoformans polysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1829-36.
1998: MM Lin; NS Green; W Zhang; Matthew D Scharff
The effects of E mu, 3'alpha (hs 1,2) and 3'kappa enhancers on mutation of an Ig-VDJ-Cgamma2a Ig heavy gene in cultured B cells.
International immunology 1998;10(8):1121-9.
1998: Arturo Casadevall; Wendy Cleare; Marta Feldmesser; Aharona Glatman-Freedman; David Goldman; Thomas R Kozel; Nikoletta Lendvai; J Mukherjee; Liise-anne Pirofski; J Rivera; AL Rosas; Matthew D Scharff; Philippe Valadon; K Westin; Z Zhong
Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies.
Antimicrobial agents and chemotherapy 1998;42(6):1437-46.
1998: NS Green; MM Lin; Matthew D Scharff
Immunoglobulin hypermutation in cultured cells.
Immunological reviews 1998;162():77-87.
1998: NS Green; MM Lin; Matthew D Scharff
Somatic hypermutation of antibody genes: a hot spot warms up.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(3):227-34.
1998: R R Yuan; Gadi Spira; J Oh; Melia Paizi; Arturo Casadevall; Matthew D Scharff
Isotype switching increases efficacy of antibody protection against Cryptococcus neoformans infection in mice.
Infection and immunity 1998;66(3):1057-62.
1998: R Yuan; Raphael Clynes; J Oh; Jeffrey V Ravetch; Matthew D Scharff
Antibody-mediated modulation of Cryptococcus neoformans infection is dependent on distinct Fc receptor functions and IgG subclasses.
The Journal of experimental medicine 1998;187(4):641-8.
1997: AC Young; Philippe Valadon; Arturo Casadevall; Matthew D Scharff; James C Sacchettini
The three-dimensional structures of a polysaccharide binding antibody to Cryptococcus neoformans and its complex with a peptide from a phage display library: implications for the identification of peptide mimotopes.
Journal of molecular biology 1997;274(4):622-34.
1997: MM Lin; M Zhu; Matthew D Scharff
Sequence dependent hypermutation of the immunoglobulin heavy chain in cultured B cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5284-9.
1997: R R Yuan; Arturo Casadevall; J Oh; Matthew D Scharff
T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2483-8.
1997: B Gaynor; Chaim Putterman; Philippe Valadon; L Spatz; Matthew D Scharff; Betty Diamond
Peptide inhibition of glomerular deposition of an anti-DNA antibody.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1955-60.
1997: G Nussbaum; Wendy Cleare; Arturo Casadevall; Matthew D Scharff; Philippe Valadon
Epitope location in the Cryptococcus neoformans capsule is a determinant of antibody efficacy.
The Journal of experimental medicine 1997;185(4):685-94.
1997: Matthew D Scharff; V Poltoratsky; NS Green
The promotion of V region hypermutation.
The Journal of experimental medicine 1997;185(2):185-8.
1996: Philippe Valadon; Matthew D Scharff
Enhancement of ELISAs for screening peptides in epitope phage display libraries.
Journal of immunological methods 1996;197(1-2):171-9.
1996: Philippe Valadon; G Nussbaum; L F Boyd; David Margulies; Matthew D Scharff
Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.
Journal of molecular biology 1996;261(1):11-22.
1996: M Lin; Gadi Spira; Matthew D Scharff
Molecular comparison of cultured hybridoma cells that switch isotypes at high and low rates.
Somatic cell and molecular genetics 1996;22(4):329-40.
1996: M Zhu; NS Green; J L Rabinowitz; Matthew D Scharff
Differential V region mutation of two transfected Ig genes and their interaction in cultured B cell lines.
The EMBO journal 1996;15(11):2738-47.
1996: G Nussbaum; R Yuan; Arturo Casadevall; Matthew D Scharff
Immunoglobulin G3 blocking antibodies to the fungal pathogen Cryptococcus neoformans.
The Journal of experimental medicine 1996;183(4):1905-9.
1995: J Mukherjee; Matthew D Scharff; Arturo Casadevall
Variable efficacy of passive antibody administration against diverse Cryptococcus neoformans strains.
Infection and immunity 1995;63(9):3353-9.
1995: NS Green; J L Rabinowitz; M Zhu; B J Kobrin; Matthew D Scharff
Immunoglobulin variable region hypermutation in hybrids derived from a pre-B- and a myeloma cell line.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6304-8.
1995: Arturo Casadevall; Matthew D Scharff
Return to the past: the case for antibody-based therapies in infectious diseases.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;21(1):150-61.
1995: J Mukherjee; Marta Feldmesser; Matthew D Scharff; Arturo Casadevall
Monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan enhance fluconazole efficacy.
Antimicrobial agents and chemotherapy 1995;39(7):1398-405.
1995: M Zhu; J L Rabinowitz; NS Green; B J Kobrin; Matthew D Scharff
A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2810-4.
1995: R Yuan; Arturo Casadevall; Gadi Spira; Matthew D Scharff
Isotype switching from IgG3 to IgG1 converts a nonprotective murine antibody to Cryptococcus neoformans into a protective antibody.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(4):1810-6.
1995: J Mukherjee; G Nussbaum; Matthew D Scharff; Arturo Casadevall
Protective and nonprotective monoclonal antibodies to Cryptococcus neoformans originating from one B cell.
The Journal of experimental medicine 1995;181(1):405-9.
1994: J Mukherjee; Matthew D Scharff; Arturo Casadevall
Cryptococcus neoformans infection can elicit protective antibodies in mice.
Canadian journal of microbiology 1994;40(10):888-92.
1994: Arturo Casadevall; Matthew D Scharff
Serum therapy revisited: animal models of infection and development of passive antibody therapy.
Antimicrobial agents and chemotherapy 1994;38(8):1695-702.
1994: B J Kobrin; C Schiff; D Zivion; Matthew D Scharff; Gadi Spira
In vitro activation of a nonproductive immunoglobulin allele by a single base pair insertion.
Hybridoma 1994;13(4):257-61.
1994: S L Zebedee; R K Koduri; J Mukherjee; S Mukherjee; Sunhee C Lee; D F Sauer; Matthew D Scharff; Arturo Casadevall
Mouse-human immunoglobulin G1 chimeric antibodies with activities against Cryptococcus neoformans.
Antimicrobial agents and chemotherapy 1994;38(7):1507-14.
1994: Gadi Spira; P Gregor; H L Aguila; Matthew D Scharff
Clonal variants of hybridoma cells that switch isotype at a high frequency.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3423-7.
1994: J Mukherjee; lionel zuckier; Matthew D Scharff; Arturo Casadevall
Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B.
Antimicrobial agents and chemotherapy 1994;38(3):580-7.
1994: S Mukherjee; Sunhee C Lee; J Mukherjee; Matthew D Scharff; Arturo Casadevall
Monoclonal antibodies to Cryptococcus neoformans capsular polysaccharide modify the course of intravenous infection in mice.
Infection and immunity 1994;62(3):1079-88.
1994: lionel zuckier; L Georgescu; C J Chang; Matthew D Scharff; S L Morrison
The use of severe combined immunodeficiency mice to study the metabolism of human immunoglobulin G.
Cancer 1994;73(3 Suppl):794-9.
1993: Gadi Spira; P D Gregor; Matthew D Scharff
The use of chemiluminescence and the ELISA spot assay to identify and enumerate rare immunoglobulin switch variants.
Journal of immunological methods 1993;165(2):263-8.
1993: J Mukherjee; Arturo Casadevall; Matthew D Scharff
Mu switch region deletion is associated with both T cell independent and T cell dependent responses.
Molecular immunology 1993;30(11):1049-55.
1993: J Mukherjee; Liise-anne Pirofski; Matthew D Scharff; Arturo Casadevall
Antibody-mediated protection in mice with lethal intracerebral Cryptococcus neoformans infection.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3636-40.
1993: J Mukherjee; Arturo Casadevall; Matthew D Scharff
Molecular characterization of the humoral responses to Cryptococcus neoformans infection and glucuronoxylomannan-tetanus toxoid conjugate immunization.
The Journal of experimental medicine 1993;177(4):1105-16.
1993: Liise-anne Pirofski; E K Thomas; Matthew D Scharff
Variable region gene utilization and mutation in a group of neutralizing murine anti-human immunodeficiency virus type 1 principal neutralizing determinant antibodies.
AIDS research and human retroviruses 1993;9(1):41-9.
1992: J Mukherjee; Matthew D Scharff; Arturo Casadevall
Protective murine monoclonal antibodies to Cryptococcus neoformans.
Infection and immunity 1992;60(11):4534-41.
1992: Arturo Casadevall; J Mukherjee; Matthew D Scharff
Monoclonal antibody based ELISAs for cryptococcal polysaccharide.
Journal of immunological methods 1992;154(1):27-35.
1992: Arturo Casadevall; J Mukherjee; S J Devi; R Schneerson; J B Robbins; Matthew D Scharff
Antibodies elicited by a Cryptococcus neoformans-tetanus toxoid conjugate vaccine have the same specificity as those elicited in infection.
The Journal of infectious diseases 1992;165(6):1086-93.
1992: Arturo Casadevall; L F Freundlich; L Marsh; Matthew D Scharff
Extensive allelic variation in Cryptococcus neoformans.
Journal of clinical microbiology 1992;30(5):1080-4.
1992: Gadi Spira; Matthew D Scharff
Identification of rare immunoglobulin switch variants using the ELISA spot assay.
Journal of immunological methods 1992;148(1-2):121-9.
1992: J L Rabinowitz; NS Green; Matthew D Scharff
How to zap a kappa.
Current biology : CB 1992;2(1):10-2.
1992: Betty Diamond; J B Katz; E Paul; Cynthia Aranow; D Lustgarten; Matthew D Scharff
The role of somatic mutation in the pathogenic anti-DNA response.
Annual review of immunology 1992;10():731-57.
1991: Arturo Casadevall; Matthew D Scharff
The mouse antibody response to infection with Cryptococcus neoformans: VH and VL usage in polysaccharide binding antibodies.
The Journal of experimental medicine 1991;174(1):151-60.
1991: Liise-anne Pirofski; M S Horwitz; Matthew D Scharff; Stephen M Factor
Murine adenovirus infection of SCID mice induces hepatic lesions that resemble human Reye syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4358-62.
1991: Seung-Uon Shin; Ronald A DePinho; Donald J Zack; S Rudikoff; Matthew D Scharff
Instability of immunoglobulin genes in S107 cell line.
Somatic cell and molecular genetics 1991;17(3):259-76.
1991: B J Kobrin; S Buhl; M J Shulman; Matthew D Scharff
A V region mutation in a phosphocholine-binding monoclonal antibody results in loss of antigen binding.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(6):2017-20.
1991: D L French; R R Pollock; H L Aguila; Matthew D Scharff
The molecular and biochemical characterization of mutant monoclonal antibodies with increased antigen binding.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(6):2010-6.
1991: S M Behar; D L Lustgarten; S Corbet; Matthew D Scharff
Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice.
The Journal of experimental medicine 1991;173(3):731-41.
1990: Liise-anne Pirofski; Arturo Casadevall; L Rodriguez; lionel zuckier; Matthew D Scharff
Current state of the hybridoma technology.
Journal of clinical immunology 1990;10(6 Suppl):5S-12S; discussion 12S-14S.
1990: R R Pollock; D L French; J P Metlay; Barbara K Birshtein; Matthew D Scharff
Intravascular metabolism of normal and mutant mouse immunoglobulin molecules.
European journal of immunology 1990;20(9):2021-7.
1989: N C Chien; Victoria A Roberts; A M Giusti; Matthew D Scharff; Elizabeth D Getzoff
Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5532-6.
1989: lionel zuckier; L D Rodriguez; Matthew D Scharff
Immunologic and pharmacologic concepts of monoclonal antibodies.
Seminars in nuclear medicine 1989;19(3):166-86.
1989: D L French; R Laskov; Matthew D Scharff
The role of somatic hypermutation in the generation of antibody diversity.
Science (New York, N.Y.) 1989;244(4909):1152-7.
1989: S M Behar; N C Chien; S Corbet; Betty Diamond; Elizabeth D Getzoff; D Lustgarten; Victoria A Roberts; Matthew D Scharff; Seung-Uon Shin
Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():921-31.
1989: S M Behar; S Corbet; Betty Diamond; Matthew D Scharff
The molecular origin of anti-DNA antibodies.
International reviews of immunology 1989;5(1):23-42.
1988: S M Behar; Matthew D Scharff
Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):3970-4.
1988: Gadi Spira; H L Aguila; Matthew D Scharff
T15 PC-binding monoclonal antibodies retain specificity when they switch from IgM to IgG.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(8):2675-80.
1988: R R Pollock; D L French; M L Gefter; Matthew D Scharff
Identification of mutant monoclonal antibodies with increased antigen binding.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2298-302.
1988: N C Chien; R R Pollock; C Desaymard; Matthew D Scharff
Point mutations cause the somatic diversification of IgM and IgG2a antiphosphorylcholine antibodies.
The Journal of experimental medicine 1988;167(3):954-73.
1988: S M Behar; B Fischer; Betty Diamond; Matthew D Scharff
Variable region gene utilization and environmental antigens in autoimmunity.
Monographs in allergy 1988;24():297-306.
1987: A M Giusti; N C Chien; Donald J Zack; Seung-Uon Shin; Matthew D Scharff
Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2926-30.
1987: Matthew D Scharff; H L Aguila; S M Behar; N C Chien; Ronald A DePinho; D L French; R R Pollock; Seung-Uon Shin
Studies on the somatic instability of immunoglobulin genes in vivo and in cultured cells.
Immunological reviews 1987;96():75-90.
1987: D French; T Kelly; S Buhl; Matthew D Scharff
Somatic cell genetic analysis of myelomas and hybridomas.
Methods in enzymology 1987;151():50-66.
1987: Scott W Burchiel; R R Pollock; D G Covell; G Fuller; Matthew D Scharff
Pharmacokinetic analysis of biosynthetically radiolabeled mouse monoclonal antibodies in normal rhesus monkeys.
International journal of immunopharmacology 1987;9(8):913-8.
1986: Matthew D Scharff; Ronald A DePinho; S Behar; C Beychok; Seung-Uon Shin; D French
The role of monoclonal antibodies and the recombinant DNA technology in studying autoantibody production.
Cellular immunology 1986;99(1):29-37.
1986: N Chien; A M Giusti; Donald J Zack; D French; Seung-Uon Shin; Betty Diamond; Matthew D Scharff
Effect of somatic mutation on antibody affinity and specificity.
The Mount Sinai journal of medicine, New York 1986;53(3):181-6.
1986: Ronald A DePinho; L B Feldman; Matthew D Scharff
Tailor-made monoclonal antibodies.
Annals of internal medicine 1986;104(2):225-33.
1985: Z Steplewski; G Spira; M Blaszczyk; M D Lubeck; Andreas Radbruch; Harald Illges; D Herlyn; K Rajewsky; Matthew D Scharff
Isolation and characterization of anti-monosialoganglioside monoclonal antibody 19-9 class-switch variants.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(24):8653-7.
1985: G Spira; R R Pollock; A Bargellesi; Matthew D Scharff
Monoclonal antibodies: a potentially powerful tool in the diagnosis and treatment of infectious diseases.
European journal of clinical microbiology 1985;4(3):251-6.
1985: Betty Diamond; N Chien; Matthew D Scharff
Somatic mutation alters affinity and specificity.
Annales de l'Institut Pasteur. Immunologie 1985;136C(2):267-71.
1985: J L Teillaud; Betty Diamond; R R Pollock; V Fajtova; Matthew D Scharff
Fc receptors on cultured myeloma and hybridoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(3):1774-9.
1984: G Spira; A Bargellesi; J L Teillaud; Matthew D Scharff
The identification of monoclonal class switch variants by sib selection and an ELISA assay.
Journal of immunological methods 1984;74(2):307-15.
1984: C Desaymard; A M Giusti; Matthew D Scharff
Rat anti-T15 monoclonal antibodies with specificity for VH- and VH-VL epitopes.
Molecular immunology 1984;21(10):961-7.
1984: Betty Diamond; Matthew D Scharff
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(18):5841-4.
1984: R R Pollock; J L Teillaud; Matthew D Scharff
Monoclonal antibodies: a powerful tool for selecting and analyzing mutations in antigens and antibodies.
Annual review of microbiology 1984;38():389-417.
1983: J L Teillaud; C Desaymard; A M Giusti; B Haseltine; R R Pollock; D E Yelton; Donald J Zack; Matthew D Scharff
Monoclonal antibodies reveal the structural basis of antibody diversity.
Science (New York, N.Y.) 1983;222(4625):721-6.
1983: P Thammana; Matthew D Scharff
Immunoglobulin heavy chain class switch from IgM to IgG in a hybridoma.
European journal of immunology 1983;13(8):614-9.
1982: Betty Diamond; Matthew D Scharff
Monoclonal antibodies.
JAMA : the journal of the American Medical Association 1982;248(23):3165-9.
1982: D E Yelton; Matthew D Scharff
Mutant monoclonal antibodies with alterations in biological functions.
The Journal of experimental medicine 1982;156(4):1131-48.
1982: S Rudikoff; A M Giusti; W D Cook; Matthew D Scharff
Single amino acid substitution altering antigen-binding specificity.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(6):1979-83.
1982: W D Cook; S Rudikoff; A M Giusti; Matthew D Scharff
Somatic mutation in a cultured mouse myeloma cell affects antigen binding.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(4):1240-4.
1982: Matthew D Scharff
Somatic cell genetics of immunoglobulin production.
Cellular immunology 1982;66(1):29-33.
1981: Matthew D Scharff; S Roberts
Present status and future prospects for the hybridoma technology.
In vitro 1981;17(12):1072-7.
1981: Donald J Zack; S L Morrison; W D Cook; W Dackowski; Matthew D Scharff
Somatically generated mouse myeloma variants synthesizing IgA half-molecules.
The Journal of experimental medicine 1981;154(5):1554-69.
1981: S P Kwan; E E Max; J G Seidman; P Leder; Matthew D Scharff
Two kappa immunoglobulin genes are expressed in the myeloma S107.
Cell 1981;26(1 Pt 1):57-66.
1981: S L Morrison; Matthew D Scharff
Mutational events in mouse myeloma cells.
Critical reviews in immunology 1981;3(1):1-22.
1981: Betty Diamond; D E Yelton; Matthew D Scharff
Monoclonal antibodies. A new technique for producing serologic reagents.
The New England journal of medicine 1981;304(22):1344-9.
1981: S P Kwan; S Rudikoff; J G Seidman; P Leder; Matthew D Scharff
Nucleic acid and protein sequences of phosphocholine-binding light chains.
The Journal of experimental medicine 1981;153(5):1366-70.
1981: Matthew D Scharff; S Roberts; P Thammana
Monoclonal antibodies.
The Journal of infectious diseases 1981;143(3):346-51.
1981: D E Yelton; C Desaymard; Matthew D Scharff
Use of monoclonal anti-mouse immunoglobulin to detect mouse antibodies.
Hybridoma 1981;1(1):5-11.
1981: D E Yelton; Matthew D Scharff
Monoclonal antibodies: a powerful new tool in biology and medicine.
Annual review of biochemistry 1981;50():657-80.
1981: P Leder; E E Max; J G Seidman; S P Kwan; Matthew D Scharff; M Nau; B Norman
Recombination events that activate, diversify, and delete immunoglobulin genes.
Cold Spring Harbor symposia on quantitative biology 1981;45 Pt 2():859-65.
1981: Matthew D Scharff; S Roberts; P Thammana
Hybridomas as a source of antibodies.
Hospital practice (Office ed.) 1981;16(1):61-6.
1980: J G Seidman; M M Nau; B Norman; S P Kwan; Matthew D Scharff; P Leder
Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):6022-6.
1980: D E Yelton; W D Cook; Matthew D Scharff
Somatic variants in mouse myeloma and hybridoma cell lines.
Transplantation proceedings 1980;12(3):439-42.
1980: D E Yelton; Matthew D Scharff
Monoclonal antibodies.
American scientist 1980;68(5):510-6.
1980: Betty Diamond; Matthew D Scharff
IgG1 and IgG2b share the Fc receptor on mouse macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1980;125(2):631-3.
1980: W Cieplinski; Matthew D Scharff
Membrane-associated ribosomes in producing and nonproducing mouse myeloma cells.
Journal of cellular physiology 1980;103(3):447-53.
1980: W D Cook; S Rudikoff; A M Giusti; Donald J Zack; T Kelly; Matthew D Scharff
Antigen binding variants of the S107 mouse myeloma cell line.
Progress in clinical and biological research 1980;42():217-30.
1979: W Newman; Betty Diamond; P Flomenberg; Matthew D Scharff; B R Bloom
Response of a continuous macrophage-like cell line to MIF.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(5):2292-7.
1979: Betty Diamond; Barbara K Birshtein; Matthew D Scharff
Site of binding of mouse IgG2b to the Fc receptor on mouse macrophages.
The Journal of experimental medicine 1979;150(3):721-6.
1979: S L Morrison; Matthew D Scharff
A mouse myeloma variant with a defect in light chain synthesis.
European journal of immunology 1979;9(6):461-5.
1978: B R Bloom; Betty Diamond; R Muschel; N Rosen; Jonathan P Schneck; G Damiani; O Rosen; Matthew D Scharff
Genetic approaches to the mechanism of macrophage functions.
Federation proceedings 1978;37(13):2765-71.
1978: J N Hurley; S M Fu; H G Kunkel; G McKenna; Matthew D Scharff
Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5706-10.
1978: Betty Diamond; B R Bloom; Matthew D Scharff
The Fc receptors of primary and cultured phagocytic cells studied with homogeneous antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1978;121(4):1329-33.
1978: T Francus; B Dharmgrongartama; R Campbell; Matthew D Scharff; Barbara K Birshtein
IgG2a-producing variants of an IgG2b-producing mouse myeloma cell line.
The Journal of experimental medicine 1978;147(6):1535-50.
1978: D E Yelton; Betty Diamond; S P Kwan; Matthew D Scharff
Fusion of mouse myeloma and spleen cells.
Current topics in microbiology and immunology 1978;81():1-7.
1977: W D Cook; Matthew D Scharff
Antigen-binding mutants of mouse myeloma cells.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(12):5687-91.
1977: S Weitzman; Stanley G Nathenson; Matthew D Scharff
Abnormalities in the glycosylation of immunoglobulin heavy chain and an h-2 transplantation antigen in a mouse myeloma mutant.
Cell 1977;10(4):679-87.
1977: M L Gefter; David Margulies; Matthew D Scharff
A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells.
Somatic cell genetics 1977;3(2):231-6.
1977: David Margulies; W Cieplinski; B Dharmgrongartama; M L Gefter; S L Morrison; T Kelly; Matthew D Scharff
Regulation of immunoglobulin expression in mouse myeloma cells.
Cold Spring Harbor symposia on quantitative biology 1977;41 Pt 2():781-91.
1976: David Margulies; W M Kuehl; Matthew D Scharff
Somatic cell hybridization of mouse myeloma cells.
Cell 1976;8(3):405-15.
1976: S Weitzman; David Margulies; Matthew D Scharff
Mutations in mouse myeloma cells: implications for human multiple myeloma and the production of immunoglobulins.
Annals of internal medicine 1976;85(1):110-6.
1976: T V Rajan; Stanley G Nathenson; Matthew D Scharff
Regulatory variants for the expression of H-2 antigens. I. Isolation and characterization.
Journal of the National Cancer Institute 1976;56(6):1221-7.
1976: A Bargellesi; G Damiani; W M Kuehl; Matthew D Scharff
Synthesis of immunoglobulin by substrate attached mouse myeloma cells.
Journal of cellular physiology 1976;88(2):247-51.
1976: S Weitzman; Matthew D Scharff
Mouse myeloma mutants blocked in the assembly, glycosylation and secretion of immunoglobulin.
Journal of molecular biology 1976;102(2):237-52.
1976: R Baumal; Matthew D Scharff
Immunoglobulin biosynthesis by the MOPC 173 mouse myeloma tumor and a variant spleen clone.
Journal of immunology (Baltimore, Md. : 1950) 1976;116(1):65-74.
1975: W M Kuehl; B A Kaplan; Matthew D Scharff
Characterization of light chain and light chain constant region fragment mRNAs in MPC 11 mouse myeloma cells and variants.
Cell 1975;5(2):139-47.
1975: J L Preud'Homme; Barbara K Birshtein; Matthew D Scharff
Variants of a mouse myeloma cell line that synthesize immunoglobulin heavy chains having an altered serotype.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(4):1427-30.
1975: S L Morrison; Matthew D Scharff
Heavy chain-producing variants of a mouse myeloma cell line.
Journal of immunology (Baltimore, Md. : 1950) 1975;114(2 Pt 1):655-9.
1974: W M Kuehl; Matthew D Scharff
Synthesis of a carboxyl-terminal (constant region) fragment of the immunoglobulin light chain by a mouse myeloma cell line.
Journal of molecular biology 1974;89(3):409-21.
1974: R Laskov; Matthew D Scharff
Independent synthesis of light and heavy chains: quantitation of light-chain production by mouse myeloma variants.
The Journal of experimental medicine 1974;140(4):1112-6.
1974: Barbara K Birshtein; J L Preud'homme; Matthew D Scharff
Variants of mouse myeloma cells that produce short immunoglobulin heavy chains.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(9):3478-82.
1974: J L Preud'homme; Matthew D Scharff
The capping of surface immunoglobulin on mouse myeloma cells.
Journal of immunology (Baltimore, Md. : 1950) 1974;113(2):702-4.
1974: J N Buxbaum; Susan Zolla-Pazner; Matthew D Scharff; E C Franklin
The synthesis and assembly of immunoglobulins by malignant human plasmacytes. 3. Heterogeneity in IgA polymer assembly.
European journal of immunology 1974;4(5):367-9.
1974: S L Morrison; R Baumal; Barbara K Birshtein; U M Kuehl; J L Preud'homme; L Frank; T Jasek; Matthew D Scharff
The identification of mouse myeloma cells which have undergone mutations in immunoglobulin production.
Society of General Physiologists series 1974;29():233-44.
1973: R Baumal; Barbara K Birshtein; Philip Coffino; Matthew D Scharff
Mutations in immunoglobulin-producing mouse myeloma cells.
Science (New York, N.Y.) 1973;182(4108):164-6.
1973: J L Prend'homme; J Buxbaum; Matthew D Scharff
Mutagenesis of mouse myeloma cells with 'Melphalan'.
Nature 1973;245(5424):320-2.
1973: R Baumal; Matthew D Scharff
Synthesis, assembly and secretion of gamma-globulin by mouse myeloma cells. V. Balanced and unbalanced synthesis of heavy and light chains by IgG-producing tumors and cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1973;111(2):448-56.
1973: J Buxbaum; Matthew D Scharff
The synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. VI. Assembly of IgM proteins.
The Journal of experimental medicine 1973;138(1):278-88.
1973: R Baumal; Matthew D Scharff
Synthesis, assembly and secretion of mouse immunoglobulin.
Transplantation reviews 1973;14():163-83.
1973: Matthew D Scharff; R Baumal; Philip Coffino; Barbara K Birshtein; W M Kuehl
The use of mouse and human cell lines in studying the regulation of immunoglobulin production.
Birth defects original article series 1973;9(1):73-89.
1973: Matthew D Scharff
The synthesis, assembly, and secretion of immunoglobulin: a biochemical and genetic approach.
Harvey lectures 1973;(69):125-42.
1972: B N Fields; R Laskov; Matthew D Scharff
Temperature-sensitive mutants of reovirus type 3: studies on the synthesis of viral peptides.
Virology 1972;50(1):209-15.
1972: Philip Coffino; R Baumal; R Laskov; Matthew D Scharff
Cloning of mouse myeloma cells and detection of rare variants.
Journal of cellular physiology 1972;79(3):429-40.
1972: A Bargellesi; P Periman; Matthew D Scharff
Synthesis, assembly, and secretion of globulin by mouse myeloma cells. IV. Assembly of IgA.
Journal of immunology (Baltimore, Md. : 1950) 1972;108(1):126-34.
1971: R Baumal; Philip Coffino; A Bargellesi; J Buxbaum; R Laskov; Matthew D Scharff
The regulation of immunoglobulin synthesis and assembly.
Annals of the New York Academy of Sciences 1971;190():235-49.
1971: R Baumal; M Potter; Matthew D Scharff
Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. 3. Assembly of the three subclasses of IgG.
The Journal of experimental medicine 1971;134(5):1316-34.
1971: Philip Coffino; B Knowles; Stanley G Nathenson; Matthew D Scharff
Suppression of immunoglobulin synthesis by cellular hybridization.
Nature: New biology 1971;231(20):87-90.
1971: J Buxbaum; Susan Zolla-Pazner; Matthew D Scharff; E C Franklin
Synthesis and assembly of immunoglobulins by malignant human plasmacytes and lymphocytes. II. Heterogeneity of assembly in cells producing IgM proteins.
The Journal of experimental medicine 1971;133(5):1118-30.
1971: R Laskov; R Lanzerotti; Matthew D Scharff
Synthesis, assembly and secretion of gamma globulin by mouse myeloma cells. II. Assembly of IgG2b immunoglobulin by MPC 11 tumor and culture cells.
Journal of molecular biology 1971;56(2):327-39.
1971: R Baumal; B Bloom; Matthew D Scharff
Induction of long term lymphocyte lines from delayed hypersensitive human donors using specific antigen plus Epstein-Barr virus.
Nature: New biology 1971;230(1):20-1.
1971: Philip Coffino; Matthew D Scharff
Rate of somatic mutation in immunoglobulin production by mouse myeloma cells.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(1):219-23.
1970: J E Darnell; L Levintow; Matthew D Scharff
Harry Eagle.
Journal of cellular physiology 1970;76(3):241-52.
1970: J V Maizel; D F Summers; Matthew D Scharff
SDS-acrylamide gel electrophoresis and its application to the proteins of poliovirus- and adenovirus-infected human cells.
Journal of cellular physiology 1970;76(3):273-87.
1970: Matthew D Scharff; A Bargellesi; R Baumal; J Buxbaum; Philip Coffino; R Laskov
Variations in the synthesis and assembly of immunoglobulins by mouse myeloma cells: a genetic and biochemical analysis.
Journal of cellular physiology 1970;76(3):331-48.
1970: M S Horwitz; J V Maizel; Matthew D Scharff
Molecular weight of Adenovirus type 2 hexon polypeptide.
Journal of virology 1970;6(4):569-71.
1970: J Buxbaum; E C Franklin; Matthew D Scharff
Immunoglobulin M heavy chain disease: intracellular origin of the mu chain fragment.
Science (New York, N.Y.) 1970;169(3947):770-3.
1970: Susan Zolla-Pazner; J Buxbaum; E C Franklin; Matthew D Scharff
Synthesis and assembly of immunoglobulins by malignant human plasmacytes. I. Myelomas producing gamma-chains and light chains.
The Journal of experimental medicine 1970;132(1):148-62.
1970: R Laskov; Matthew D Scharff
Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. I. Adaptation of the Merwin plasma cell tumor-11 to culture, cloning, and characterization of gamma globulin subunits.
The Journal of experimental medicine 1970;131(3):515-41.
1970: Philip Coffino; R Laskov; Matthew D Scharff
Immunoglobulin production: method for quantitatively detecting variant myeloma cells.
Science (New York, N.Y.) 1970;167(3915):186-8.
1970: Matthew D Scharff; R Laskov
Synthesis and assembly of immunoglobulin polypeptide chains.
Progress in allergy 1970;14():37-80.
1969: M S Horwitz; Matthew D Scharff; J V Maizel
Synthesis and assembly of adenovirus 2. I. Polypeptide synthesis, assembly of capsomeres, and morphogenesis of the virion.
Virology 1969;39(4):682-94.
1969: A L Shapiro; I M Siegel; Matthew D Scharff; E Robbins
Characteristics of cultured lens epithelium.
Investigative ophthalmology 1969;8(4):393-400.
1969: D O White; Matthew D Scharff; J V Maizel
The polypeptides of adenovirus. 3. Synthesis in infected cells.
Virology 1969;38(3):395-406.
1969: L D Hodge; Matthew D Scharff
Effect of adenovirus on host cell DNA synthesis in synchronized cells.
Virology 1969;37(4):554-64.
1969: L D Hodge; E Robbins; Matthew D Scharff
Persistence of messenger RNA through mitosis in HeLa cells.
The Journal of cell biology 1969;40(2):497-507.
1969: L D Hodge; T W Borun; E Robbins; Matthew D Scharff
Studies on the regulation of protein synthesis in synchronized HeLa cells.
Proceedings. Canadian Cancer Conference 1969;8():130-45.
1968: J V Maizel; D O White; Matthew D Scharff
The polypeptides of adenovirus. II. Soluble proteins, cores, top components and the structure of the virion.
Virology 1968;36(1):126-36.
1968: J V Maizel; D O White; Matthew D Scharff
The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12.
Virology 1968;36(1):115-25.
1967: T W Borun; Matthew D Scharff; E Robbins
Preparation of mammalian polyribosomes with the detergent Nonidet P-40.
Biochimica et biophysica acta 1967;149(1):302-4.
1967: T W Borun; Matthew D Scharff; E Robbins
Rapidly labeled, polyribosome-associated RNA having the properties of histone messenger.
Proceedings of the National Academy of Sciences of the United States of America 1967;58(5):1977-83.
1967: E Robbins; Matthew D Scharff
The absence of a detectable G1 phase in a cultured strain of Chinese hamster lung cell.
The Journal of cell biology 1967;34(2):684-6.
1966: A L Shapiro; Matthew D Scharff; J V Maizel; J W Uhr
Synthesis of excess light chains of gamma globulin by rabbit lymph node cells.
Nature 1966;211(5046):243-5.
1966: A L Shapiro; Matthew D Scharff; J V Maizel; J W Uhr
Polyribosomal synthesis and assembly of the H and L chains of gamma globulin.
Proceedings of the National Academy of Sciences of the United States of America 1966;56(1):216-21.
1966: Matthew D Scharff; E Robbins
Polyribosome disaggregation during metaphase.
Science (New York, N.Y.) 1966;151(3713):992-5.
1966: S Tawde; Matthew D Scharff; J W Uhr
Mechanisms of gamma-globulin synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1966;96(1):1-7.
1965: Matthew D Scharff; E Robbins
Synthesis of ribosomal RNA in synchronized HeLa cells.
Nature 1965;208(5009):464-6.
1965: Matthew D Scharff; D F Summers; L Levintow
Further studies on the effect of p-fluorophenylalanine and puromycin on polio virus replication.
Annals of the New York Academy of Sciences 1965;130(1):282-90.
1965: Matthew D Scharff; J W UHR
FUNCTIONAL RIBOSOMAL UNIT OF GAMMA-GLOBULIN SYNTHESIS.
Science (New York, N.Y.) 1965;148(3670):646-8.
1965: Matthew D Scharff; J W UHR
IMMUNOLOGIC DEFICIENCY DISORDERS ASSOCIATED WITH LYMPHOPROLIFERATIVE DISEASES.
Seminars in hematology 1965;2():47-67.
1964: Matthew D Scharff; J V MAIZEL; L LEVINTOW
PHYSICAL AND IMMUNOLOGICAL PROPERTIES OF A SOLUBLE PRECURSOR OF THE POLIOVIRUS CAPSID.
Proceedings of the National Academy of Sciences of the United States of America 1964;51():329-37.
1963: Matthew D Scharff; A J SHATKIN; L LEVINTOW
ASSOCIATION OF NEWLY FORMED VIRAL PROTEIN WITH SPECIFIC POLYRIBOSOMES.
Proceedings of the National Academy of Sciences of the United States of America 1963;50():686-94.
1963: Matthew D Scharff; L LEVINTOW
Quantitative study of the formation of poliovirus antigens in infected HeLa cells.
Virology 1963;19():491-500.
1963: Matthew D Scharff; M M THOREN; N F McELVAIN; L LEVINTOW
Interruption of poliovirus RNA synthesis by p-fluorophenylalanine and puromycin.
Biochemical and biophysical research communications 1963;10():127-32.
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