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Karin Scharffetter-Kochanek

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Kamayani Singh; Honglin Wang; Anca Sindrilaru; Lisa Borkner; Martina Gatzka; Adelheid Hainzl; Thorsten Peters; Karin Scharffetter-Kochanek
Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis.
Agatha Stegemann; Adriana del Rey; Beate Eckes; Bernd L Fiebich; Sergei A Grando; Alexander Heinick; Thomas A Luger; Frank U Müller; Karin Scharffetter-Kochanek; Jan S Schulte; Anca Sindrilaru; Markus Böhm
Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.
Dongsheng Jiang; Sheila MacNeil; Yu Qi; Anca Sindrilaru; Nathan G Walker; Meinhard Wlaschek; Adelheid Hainzl; Karin Scharffetter-Kochanek
The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing.

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2013: Kamayani Singh; Honglin Wang; Anca Sindrilaru; Lisa Borkner; Martina Gatzka; Adelheid Hainzl; Thorsten Peters; Karin Scharffetter-Kochanek
Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2544-53.
2013: Agatha Stegemann; Adriana del Rey; Beate Eckes; Bernd L Fiebich; Sergei A Grando; Alexander Heinick; Thomas A Luger; Frank U Müller; Karin Scharffetter-Kochanek; Jan S Schulte; Anca Sindrilaru; Markus Böhm
Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.
Arthritis and rheumatism 2013;65(3):792-804.
2013: Dongsheng Jiang; Sheila MacNeil; Yu Qi; Anca Sindrilaru; Nathan G Walker; Meinhard Wlaschek; Adelheid Hainzl; Karin Scharffetter-Kochanek
The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing.
Biomaterials 2013;34(10):2501-15.
2013: Matthias Sendler; Nico van Rooijen; Thomas Wartmann; Frank U Weiss; Ali Aghdassi; Annegret Dummer; Walter Halangk; Burkhard Krüger; Markus M Lerch; Sudarshan Ravi Malla; Karin Scharffetter-Kochanek; Julia Mayerle
Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice.
Gut 2013;62(3):430-9.
2012: Yoshiaki Sunami; Sebastian Wissel; Bernd Baumann; Sigrid Espenlaub; Katja Fiedler; Sarah Gul; Nurdan Güldiken; Nora Hipp; Karl-Heinz Holzmann; Stefan Kochanek; Florian Kreppel; Frank Leithäuser; Tom Luedde; Karin Scharffetter-Kochanek; Marion Schneider; Anca Sindrilaru; Pavel Strnad; Thomas Wirth
Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation.
Hepatology (Baltimore, Md.) 2012;56(3):1117-28.
2012: Nicolai Treiber; Meinhard Wlaschek; Florentina Ferchiu; Pallab Maity; Karmveer Singh; Karin Scharffetter-Kochanek
The role of manganese superoxide dismutase in skin aging.
Dermato-endocrinology 2012;4(3):232-5.
2012: Maria Carolina Florian; Deidre Daria; Karin Dörr; Marie-Dominique Filippi; Matthias Gunzer; Anja Hasenberg; Anja Niebel; Markus Rojewski; Karin Scharffetter-Kochanek; Hubert Schrezenmeier; Yi Zheng; Hartmut Geiger
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation.
Cell stem cell 2012;10(5):520-30.
2012: Thorsten Peters; Susanne V Schmidt; Anca Sindrilaru; Claudia Uthoff-Hachenberg; Georg Varga; Claudia Wickenhauser; Klaus Addicks; Wilhelm Bloch; Reinhold Förster; Stephan Grabbe; Daniel Kess; Werner Muller; Tsvetelina Oreshkova; Oliver Pabst; Karin Scharffetter-Kochanek
Adaptive immune response to model antigens is impaired in murine leukocyte-adhesion deficiency-1 revealing elevated activation thresholds in vivo.
Clinical & developmental immunology 2012;2012():450738.
2012: Jan Kassubek; Albert C Ludolph; Hans-Peter Müller; Elmar H Pinkhardt; Karin Scharffetter-Kochanek; Anne-Dorte Sperfeld; Alexander Unrath; Mark Berneburg
The cerebro-morphological fingerprint of a progeroid syndrome: white matter changes correlate with neurological symptoms in xeroderma pigmentosum.
PloS one 2012;7(2):e30926.
2011: Alexander Baur; Jan Henkel; Wilhelm Bloch; Nicolai Treiber; Karin Scharffetter-Kochanek; Gert-Peter Brüggemann; Anja Niehoff
Effect of exercise on bone and articular cartilage in heterozygous manganese superoxide dismutase (SOD2) deficient mice.
Free radical research 2011;45(5):550-8.
2011: Nicolai Treiber; Pallab Maity; Karmveer Singh; Matthias Kohn; Alexander F Keist; Florentina Ferchiu; Lea Sante; Sebastian Frese; Wilhelm Bloch; Florian Kreppel; Stefan Kochanek; Anca Sindrilaru; Sebastian Iben; Josef Högel; M Ohnmacht; Lutz E Claes; Anita Ignatius; Jin H Chung; Min J Lee; York Kamenisch; Mark Berneburg; Thorsten Nikolaus; Kerstin Braunstein; Anne-Dorte Sperfeld; Albert C Ludolph; Karlis Briviba; Meinhard Wlaschek; Peter Angel; Lore Florin; Karin Scharffetter-Kochanek
Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue.
Aging cell 2011;10(2):239-54.
2011: Anca Sindrilaru; Thorsten Peters; Stefan Wieschalka; Corina Baican; Adrian Baican; Henriette Peter; Adelheid Hainzl; Susanne Schatz; Yu Qi; Andrea Schlecht; Johannes M Weiss; Meinhard Wlaschek; Cord Sunderkötter; Karin Scharffetter-Kochanek
An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice.
The Journal of clinical investigation 2011;121(3):985-97.
2011: Keith B Boyle; David Gyori; Anca Sindrilaru; Karin Scharffetter-Kochanek; Philip R Taylor; Attila Mócsai; Len R Stephens; Phillip T Hawkins
Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(5):2978-89.
2011: Olivier Toussaint; Geoffroy Weemaels; Florence Debacq-Chainiaux; Karin Scharffetter-Kochanek; Meinhard Wlaschek
Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology.
Journal of cellular physiology 2011;226(2):315-21.
2010: Lubin Fang; Marko Teuchert; Friederike Huber-Abel; Dagmar Schattauer; Corinna Hendrich; Johannes Dorst; Heinz Zettlmeissel; Meinhard Wlaschek; Karin Scharffetter-Kochanek; Tamara Kapfer; Hayrettin Tumani; Albert C Ludolph; Johannes Brettschneider
MMP-2 and MMP-9 are elevated in spinal cord and skin in a mouse model of ALS.
Journal of the neurological sciences 2010;294(1-2):51-6.
2010: Magdalena Hagn; Verena Ebel; Kai Sontheimer; Elisabeth Schwesinger; Oleg Lunov; Thamara Beyer; Dorit Fabricius; Thomas F E Barth; Andreas Viardot; Stephan Stilgenbauer; Julia Hepp; Karin Scharffetter-Kochanek; Thomas Simmet; Bernd Jahrsdörfer
CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B.
European journal of immunology 2010;40(7):2060-9.
2010: Heike A Schreiber; Andreas C Renkl; Witold Lapinski; Karin Scharffetter-Kochanek; Johannes M Weiss
Myiasis after study trip to French Guiana.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2010;8(5):357-9.
2010: Honglin Wang; Julia von Rohrscheidt; Jan Roehrbein; Thorsten Peters; Anca Sindrilaru; Daniel Kess; Klaus T Preissner; Karin Scharffetter-Kochanek
Extracellular adherence protein of Staphylococcus aureus suppresses disease by inhibiting T-cell recruitment in a mouse model of psoriasis.
The Journal of investigative dermatology 2010;130(3):743-54.
2009: Lubin Fang; Friederike Huber-Abel; Marko Teuchert; Corinna Hendrich; Johannes Dorst; Dagmar Schattauer; Heinz Zettlmeissel; Meinhard Wlaschek; Karin Scharffetter-Kochanek; Hayrettin Tumani; Albert C Ludolph; Johannes Brettschneider
Linking neuron and skin: matrix metalloproteinases in amyotrophic lateral sclerosis (ALS).
Journal of the neurological sciences 2009;285(1-2):62-6.
2009: Honglin Wang; Tatiana Syrovets; Daniel Kess; Berthold Büchele; Heidi Hainzl; Oleg Lunov; Johannes M Weiss; Karin Scharffetter-Kochanek; Thomas Simmet
Targeting NF-kappa B with a natural triterpenoid alleviates skin inflammation in a mouse model of psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4755-63.
2009: Tsvetelina Oreshkova; Honglin Wang; Anne M Seier; Anca Sindrilaru; Georg Varga; Stephan Grabbe; Karin Scharffetter-Kochanek; Thorsten Peters
Beta(2) integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice.
Immunology 2009;128(2):271-86.
2009: Alexander Kreuter; Thomas Krieg; Margitta Worm; Jörg Wenzel; Thilo Gambichler; Annegret Kuhn; Elisabeth Aberer; Karin Scharffetter-Kochanek; Nicolas Hunzelmann
[AWMF Guideline no. 013/066. Diagnosis and therapy of circumscribed scleroderma].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7 Suppl 6():S1-14.
2009: Thorsten Peters; Johannes M Weiss; Anca Sindrilaru; Honglin Wang; Tsvetelina Oreshkova; Meinhard Wlaschek; Pallab Maity; Jörg Reimann; Karin Scharffetter-Kochanek
Reactive oxygen intermediate-induced pathomechanisms contribute to immunosenescence, chronic inflammation and autoimmunity.
Mechanisms of ageing and development 2009;130(9):564-87.
2009: Anca Sindrilaru; Thorsten Peters; Jürgen Schymeinsky; Tsvetelina Oreshkova; Honglin Wang; Anne Gompf; Francesca Mannella; Meinhard Wlaschek; Cord Sunderkötter; Karl Lenhard Rudolph; Barbara Walzog; Xosé R Bustelo; Klaus-Dieter Fischer; Karin Scharffetter-Kochanek
Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils.
Blood 2009;113(21):5266-76.
2009: Honglin Wang; Thorsten Peters; Anca Sindrilaru; Karin Scharffetter-Kochanek
Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis.
The Journal of investigative dermatology 2009;129(5):1100-14.
2009: V Mayer; J Maetzke; Karin Scharffetter-Kochanek
[Punctate maculae on the back of the hands of a 44-year-old woman].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2009;60(5):428-32.
2009: Nicolai Treiber; Thorsten Peters; Anca Sindrilaru; Roman Huber; Matthias Kohn; Andre Menke; Karlis Briviba; Florian Kreppel; Abhijit Basu; Pallab Maity; Mandy Koller; Sebastian Iben; Meinhard Wlaschek; Stefan Kochanek; Karin Scharffetter-Kochanek
Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: implications for ageing and hyperplastic scar formation.
Archives of dermatological research 2009;301(4):273-87.
2009: Anton Lebedev; Karin Scharffetter-Kochanek; Sebastian Iben
A novel activity enhances promoter escape of RNA polymerase I.
Biochemical and biophysical research communications 2009;380(3):695-8.
2009: Agatha Kokot; Anca Sindrilaru; Meinhard Schiller; Cord Sunderkötter; Claus Kerkhoff; Beate Eckes; Karin Scharffetter-Kochanek; Thomas A Luger; Markus Böhm
alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?
Arthritis and rheumatism 2009;60(2):592-603.
2008: Karen E Anderson; Keith B Boyle; Keith Davidson; Tamara A M Chessa; Suhasini Kulkarni; Gavin E Jarvis; Anca Sindrilaru; Karin Scharffetter-Kochanek; Oliver Rausch; Len R Stephens; Phillip T Hawkins
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.
Blood 2008;112(13):5202-11.
2008: Karin Scharffetter-Kochanek
[Wound healing disorders].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2008;59(11):885.
2008: Philip Wenzel; Swenja Schuhmacher; Joachim Kienhöfer; Johanna Müller; Marcus Hortmann; Matthias Oelze; Eberhard Schulz; Nicolai Treiber; Toshihiro Kawamoto; Karin Scharffetter-Kochanek; Thomas Münzel; Alexander Bürkle; Markus Bachschmid; Andreas Daiber
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction.
Cardiovascular research 2008;80(2):280-9.
2008: Anton Lebedev; Karin Scharffetter-Kochanek; Sebastian Iben
Truncated Cockayne syndrome B protein represses elongation by RNA polymerase I.
Journal of molecular biology 2008;382(2):266-74.
2008: Oliver Soehnlein; Ylva Kai-Larsen; Robert Frithiof; Ole E Sorensen; Ellinor Kenne; Karin Scharffetter-Kochanek; Einar E Eriksson; Heiko Herwald; Birgitta Agerberth; Lennart Lindbom
Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages.
The Journal of clinical investigation 2008;118(10):3491-502.
2008: Lars Alexander Schneider; Ralf Hinrichs; Karin Scharffetter-Kochanek
Phototherapy and photochemotherapy.
Clinics in dermatology 2008;26(5):464-76.
2008: Anna Lutomska; Anton Lebedev; Karin Scharffetter-Kochanek; Sebastian Iben
The transcriptional response to distinct growth factors is impaired in Werner syndrome cells.
Experimental gerontology 2008;43(9):820-6.
2008: Stefania Briganti; Meinhard Wlaschek; Christina Hinrichs; Barbara Bellei; Enrica Flori; Nicolai Treiber; Sebastian Iben; Mauro Picardo; Karin Scharffetter-Kochanek
Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging.
Free radical biology & medicine 2008;45(5):636-44.
2008: Honglin Wang; Thorsten Peters; Anca Sindrilaru; Daniel Kess; Tsvetelina Oreshkova; Xuezhong Yu; Anne Maria Seier; Heike Schreiber; Meinhard Wlaschek; Robert Blakytny; Jan Röhrbein; Guido Schulz; Johannes M Weiss; Karin Scharffetter-Kochanek
TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis.
The Journal of clinical investigation 2008;118(7):2629-39.
2008: Honglin Wang; Daniel Kess; Anna-Karin B Lindqvist; Thorsten Peters; Anca Sindrilaru; Meinhard Wlaschek; Robert Blakytny; Rikard Holmdahl; Karin Scharffetter-Kochanek
A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5520-9.
2008: G Hirschfeld; L Weber; Andreas C Renkl; Karin Scharffetter-Kochanek; Johannes M Weiss
Anaphylaxis after Oseltamivir (Tamiflu) therapy in a patient with sensitization to star anise and celery-carrot-mugwort-spice syndrome.
Allergy 2008;63(2):243-4.
2008: Yaming Liang; Chen Liu; Julie Y Djeu; Bin Zhong; Thorsten Peters; Karin Scharffetter-Kochanek; Claudio Anasetti; Xuezhong Yu
Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects.
Blood 2008;111(2):954-62.
2008: Gyde Staib; Karin Scharffetter-Kochanek
Bexarotene monotherapy for patients with refractory Sézary syndrome.
Dermatologic clinics 2008;26 Suppl 1():61-3.
2007: Julia Maetzke; Ralf Hinrichs; Anja Sigge; Karin Scharffetter-Kochanek
[Centrofacial granulomatous inflammation].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2007;58(11):976-8.
2007: Céline Borlon; Florence Debacq-Chainiaux; Christina Hinrichs; Karin Scharffetter-Kochanek; Olivier Toussaint; Meinhard Wlaschek
The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype.
Experimental gerontology 2007;42(9):911-23.
2007: Felix Mottaghy; Cord Sunderkötter; Roland Schubert; Petra Wohlfart; Norbert M Blumstein; Bernd Neumaier; Gerhard Glatting; Cueneyt Ozdemir; Andreas K Buck; Karin Scharffetter-Kochanek; Sven N Reske
Direct comparison of [18F]FDG PET/CT with PET alone and with side-by-side PET and CT in patients with malignant melanoma.
European journal of nuclear medicine and molecular imaging 2007;34(9):1355-64.
2007: Lars Alexander Schneider; Meinhard Wlaschek; Joachim Dissemond; Karin Scharffetter-Kochanek
Examples for the importance of radiophysical measurements in clinical phototherapy.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(5):384-9.
2007: Lars Alexander Schneider; Ralf Hinrichs; Karin Scharffetter-Kochanek
[Indications for UVB-phototherapy].
Deutsche medizinische Wochenschrift (1946) 2007;132(16):888-91.
2007: Tatjana Dorn; Ursula Kuhn; Gerd Bungartz; Sebastian Stiller; Martina Bauer; Joachim W Ellwart; Thorsten Peters; Karin Scharffetter-Kochanek; Monika Semmrich; Melanie Laschinger; Bernhard Holzmann; Wolfgang E F Klinkert; Per thor Straten; Tania Køllgaard; Michael Sixt; Cord Brakebusch
RhoH is important for positive thymocyte selection and T-cell receptor signaling.
Blood 2007;109(6):2346-55.
2007: Martin Fuchsbauer; C Ozdemir; Karin Scharffetter-Kochanek
Pincer nail: aesthetic concept in surgery.
Journal of cosmetic dermatology 2007;6(1):27-30.
2007: S Ott; K Welt; G Hirschfeld; L Weber; Karin Scharffetter-Kochanek
[Unilateral segmental keratotic papules].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2007;58(3):261-3.
2007: Peter Elsner; Erhard Hölzle; Thomas L Diepgen; Susanne Grether-Beck; Herbert Hönigsmann; Jean Krutmann; Karin Scharffetter-Kochanek; Thomas Schwarz; Thomas Luger
Recommendation: daily sun protection in the prevention of chronic UV-induced skin damage.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(2):166-73.
2007: Anca Sindrilaru; Stephan Seeliger; Jan Ehrchen; Thorsten Peters; Johannes Roth; Karin Scharffetter-Kochanek; Cord Sunderkötter
Site of blood vessel damage and relevance of CD18 in a murine model of immune complex-mediated vasculitis.
The Journal of investigative dermatology 2007;127(2):447-54.
2007: G Hirschfeld; Anne-Dorte Sperfeld; J Kassubek; Karin Scharffetter-Kochanek; Cord Sunderkötter
[Transient global amnesia (TGA) during an oral provocation test].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2007;58(2):149-52.
2007: Georg Varga; Sandra Balkow; Martin K Wild; Andrea Stadtbaeumer; Mathias B W Krummen; Tobias Rothoeft; Tetsuya Higuchi; Stefan Beissert; Klaus Wethmar; Karin Scharffetter-Kochanek; Dietmar Vestweber; Stephan Grabbe
Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation.
Blood 2007;109(2):661-9.
2007: Jürgen Schymeinsky; Cornelia Then; Anca Sindrilaru; Ronald Gerstl; Zoltan Jakus; Victor L J Tybulewicz; Karin Scharffetter-Kochanek; Barbara Walzog
Syk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytes.
PloS one 2007;2(11):e1132.
2007: J Grimmer; T Weiss; Lutz Weber; D Meixner; Karin Scharffetter-Kochanek
Successful treatment of lichen amyloidosis with combined bath PUVA photochemotherapy and oral acitretin.
Clinical and experimental dermatology 2007;32(1):39-42.
2006: Jürgen Schymeinsky; Anca Sindrilaru; David Frommhold; Markus Sperandio; Ronald Gerstl; Cornelia Then; Attila Mócsai; Karin Scharffetter-Kochanek; Barbara Walzog
The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for beta2 integrin (CD11/CD18)-mediated neutrophil migration.
Blood 2006;108(12):3919-27.
2006: Daniel Kess; Anna-Karin B Lindqvist; Thorsten Peters; Honglin Wang; Jan Zamek; Roswitha Nischt; Karl W Broman; Robert Blakytny; Thomas Krieg; Rikard Holmdahl; Karin Scharffetter-Kochanek
Identification of susceptibility loci for skin disease in a murine psoriasis model.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4612-9.
2006: J Rampf; Cord Sunderkötter; G Hirschfeld; Karin Scharffetter-Kochanek; J M Weiss
Methylenetetrahydrofolate reductase polymorphism associated with moderate hyperhomocysteinaemia in a patient with livedo vasculopathy: treatment with vitamin supplementation and low molecular weight heparin.
The British journal of dermatology 2006;155(4):850-2.
2006: Sigrun Ressler; Jirina Bartkova; Harald Niederegger; Jiri Bartek; Karin Scharffetter-Kochanek; Pidder Jansen-Dürr; Meinhard Wlaschek
p16INK4A is a robust in vivo biomarker of cellular aging in human skin.
Aging cell 2006;5(5):379-89.
2006: Lars Alexander Schneider; Joachim Dissemond; Edith Schwamborn; Meinhard Wlaschek; Peter Brenneisen; Karin Scharffetter-Kochanek
Tirilazad amelioriates extracellular effects of photooxidative stress by sealing the membrane of UVA irradiated human dermal fibroblasts.
European journal of dermatology : EJD 2006;16(5):530-6.
2006: Jackie R Bickenbach; Molly Kulesz-Martin; Richard Clark; Karin Scharffetter-Kochanek
Highlights of clinician/scientist translational discussion session.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2006;11(1):140-1.
2006: Thorsten Peters; Anca Sindrilaru; Honglin Wang; Tsvetelina Oreshkova; Andreas C Renkl; Daniel Kess; Karin Scharffetter-Kochanek
CD18 in monogenic and polygenic inflammatory processes of the skin.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2006;11(1):7-15.
2006: Thorsten Peters; Wilhelm Bloch; Claudia Wickenhauser; Samir Tawadros; Tsvetelina Oreshkova; Daniel Kess; Thomas Krieg; Werner Muller; Karin Scharffetter-Kochanek
Terminal B cell differentiation is skewed by deregulated interleukin-6 secretion in beta2 integrin-deficient mice.
Journal of leukocyte biology 2006;80(3):599-607.
2006: Honglin Wang; Thorsten Peters; Daniel Kess; Anca Sindrilaru; Tsvetelina Oreshkova; Nico van Rooijen; Athanasios Stratis; Andreas C Renkl; Cord Sunderkötter; Meinhard Wlaschek; Ingo Haase; Karin Scharffetter-Kochanek
Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation.
The Journal of clinical investigation 2006;116(8):2105-14.
2006: Athanasios Stratis; Manolis Pasparakis; Rudolf A Rupec; Doreen Markur; Karin Hartmann; Karin Scharffetter-Kochanek; Thorsten Peters; Nico van Rooijen; Thomas Krieg; Ingo Haase
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation.
The Journal of clinical investigation 2006;116(8):2094-104.
2006: K Gethöffer; Lars Alexander Schneider; T Peters; Lutz Weber; Karin Scharffetter-Kochanek
[Acneiform skin eruption in patients with metastatic colorectal carcinoma].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2006;57(7):628-31.
2006: Lars Alexander Schneider; W Bloch; K Kopp; A Hainzl; Petra Rettberg; Meinhard Wlaschek; Gerda Horneck; Karin Scharffetter-Kochanek
8-Isoprostane is a dose-related biomarker for photo-oxidative ultraviolet (UV) B damage in vivo: a pilot study with personal UV dosimetry.
The British journal of dermatology 2006;154(6):1147-54.
2006: Ralf Hinrichs; Lutz Weber; Karin Scharffetter-Kochanek
[Chronic ulceration of one side of the face].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2006;57(5):455-7.
2006: Margit A Huber; Norbert Kraut; Norbert Schweifer; Helmut Dolznig; Ralf Uwe Peter; Roland D Schubert; Karin Scharffetter-Kochanek; Hubert Pehamberger; Pilar Garin-Chesa
Expression of stromal cell markers in distinct compartments of human skin cancers.
Journal of cutaneous pathology 2006;33(2):145-55.
2006: Hanke Mollnau; Philip Wenzel; Matthias Oelze; Nicolai Treiber; Andrea Pautz; Eberhard Schulz; Swenja Schuhmacher; Kurt Reifenberg; Dirk Stalleicken; Karin Scharffetter-Kochanek; Hartmut Kleinert; Thomas Münzel; Andreas Daiber
Mitochondrial oxidative stress and nitrate tolerance--comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/- mice.
BMC cardiovascular disorders 2006;6():44.
2006: Margit A Huber; Gyde Staib; Hubert Pehamberger; Karin Scharffetter-Kochanek
Management of refractory early-stage cutaneous T-cell lymphoma.
American journal of clinical dermatology 2006;7(3):155-69.
2006: Lars Alexander Schneider; Mathias Schmid; Gyde Staib; Tina Weiss; Karin Scharffetter-Kochanek; Lutz Weber
Cutaneous infiltrations can herald an inapparent myelodysplastic syndrome.
Acta dermato-venereologica 2006;86(2):172-3.
2006: Julia Maetzke; Anne-Dorte Sperfeld; Karin Scharffetter-Kochanek; Cord Sunderkötter
Vesicular and bullous eczema in response to intravenous immunoglobulins (IVIG).
Allergy 2006;61(1):145-6.
2006: Lars Alexander Schneider; Joachim Dissemond; Peter Brenneisen; Adelheid Hainzl; Karlis Briviba; Meinhard Wlaschek; Karin Scharffetter-Kochanek
Adaptive cellular protection against UVA-1-induced lipid peroxidation in human dermal fibroblasts shows donor-to-donor variability and is glutathione dependent.
Archives of dermatological research 2006;297(7):324-8.
2006: Ralf Hinrichs; T Weiss; E Peschke; Karin Scharffetter-Kochanek; Lutz Weber
A reticular variant of elastolytic giant cell granuloma.
Clinical and experimental dermatology 2006;31(1):42-4.
2006: Ruth Schruefer; Silke Sulyok; Jürgen Schymeinsky; Thorsten Peters; Karin Scharffetter-Kochanek; Barbara Walzog
The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of CD18-deficient mice.
Journal of vascular research 2006;43(1):1-11.
2005: Lars Alexander Schneider; Lutz Weber; Julia Maetzke; Karin Scharffetter-Kochanek
A swollen face after dental surgery.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2005;3(12):987-9.
2005: Tina Weiss; Lutz Weber; Karin Scharffetter-Kochanek; Johannes M Weiss
Solitary cutaneous dendritic cell tumor in a child: role of dendritic cell markers for the diagnosis of skin Langerhans cell histiocytosis.
Journal of the American Academy of Dermatology 2005;53(5):838-44.
2005: Thorsten Peters; Anca Sindrilaru; Boris Hinz; Ralf Hinrichs; André Menke; Ezz Al Din Al-Azzeh; Katrin Holzwarth; Tsvetelina Oreshkova; Honglin Wang; Daniel Kess; Barbara Walzog; Silke Sulyok; Cord Sunderkötter; Wilhelm Friedrich; Meinhard Wlaschek; Thomas Krieg; Karin Scharffetter-Kochanek
Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation.
The EMBO journal 2005;24(19):3400-10.
2005: Meinhard Wlaschek; Karin Scharffetter-Kochanek
Oxidative stress in chronic venous leg ulcers.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2005;13(5):452-61.
2005: Susanne Grether-Beck; Meinhard Wlaschek; Jean Krutmann; Karin Scharffetter-Kochanek
[Photodamage and photoaging--prevention and treatment].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2005;3 Suppl 2():S19-25.
2005: Lars Alexander Schneider; Julia Maetzke; Gyde Staib; Karin Scharffetter-Kochanek
C1-INH and C3/C4 levels do not correlate with long-term danazole dosage and HAE-1 attack-free interval.
Allergy 2005;60(9):1214-5.
2005: Andreas Daiber; Matthias Oelze; Silke Sulyok; Meike Coldewey; Eberhard Schulz; Nicolai Treiber; Ulrich Hink; Alexander Mülsch; Karin Scharffetter-Kochanek; Thomas Münzel
Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance.
Molecular pharmacology 2005;68(3):579-88.
2005: Oliver Pabst; Thorsten Peters; Niklas Czeloth; Günter Bernhardt; Karin Scharffetter-Kochanek; Reinhold Förster
Cutting edge: egress of newly generated plasma cells from peripheral lymph nodes depends on beta 2 integrin.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7492-5.
2005: Maria Strassburger; Wilhelm Bloch; Silke Sulyok; Jutta Schüller; Alexander F Keist; Annette Schmidt; Jutta Wenk; Thorsten Peters; Meinhard Wlaschek; Jacek Lenart; Thomas Krieg; Martin Hafner; Angelika Kümin; Sabine Werner; Werner Muller; Karin Scharffetter-Kochanek
Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo.
Free radical biology & medicine 2005;38(11):1458-70.
2005: R D Schubert; T Weiss; J M Weiss; Karin Scharffetter-Kochanek; Lutz Weber
[Multiple quickly changing tumors on the head and trunk of a 47-year old man].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2005;56(6):586-9.
2005: K Welt; Ralf Hinrichs; S Ott; M Thalmann; J Dieckmännken; Lars Alexander Schneider; Gyde Staib; Karin Scharffetter-Kochanek
Anaphylaxis after the ingestion of lamb meat.
Allergy 2005;60(4):545.
2005: Julia Maetzke; Ralf Hinrichs; Lars Alexander Schneider; Karin Scharffetter-Kochanek
Unexpected delayed-type hypersensitivity skin reactions to the ultra-low-molecular-weight heparin fondaparinux.
Allergy 2005;60(3):413-5.
2005: Emmanouil Chavakis; Alexandra Aicher; Christopher Heeschen; Ken-ichiro Sasaki; Ralf Kaiser; Naual El Makhfi; Carmen Urbich; Thorsten Peters; Karin Scharffetter-Kochanek; Andreas M Zeiher; Triantafyllos Chavakis; Stefanie Dimmeler
Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells.
The Journal of experimental medicine 2005;201(1):63-72.
2005: Peter Kurschat; S Hess; Nicolas Hunzelmann; Karin Scharffetter-Kochanek
Keratoacanthoma centrifugum marginatum accompanied by extensive granulomatous foreign body reaction.
Dermatology online journal 2005;11(2):16.
2005: C Ozdemir; T Weiss; Lutz Weber; M Merkel; Karin Scharffetter-Kochanek
[Multiple hyperpigmented facial plaques].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2005;56(1):76-80.
2004: Jutta Wenk; Jutta Schüller; Christina Hinrichs; Tatiana Syrovets; Ninel Azoitei; Maurizio Podda; Meinhard Wlaschek; Peter Brenneisen; Lars Alexander Schneider; Andrea Sabiwalsky; Thorsten Peters; Silke Sulyok; Joachim Dissemond; Matthias Schauen; Thomas Krieg; Thomas Wirth; Thomas Simmet; Karin Scharffetter-Kochanek
Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release.
The Journal of biological chemistry 2004;279(44):45634-42.
2004: Lars Alexander Schneider; Lutz Weber; Andreas Viardot; R Schubert; Ralf Hinrichs; Karin Scharffetter-Kochanek
Cutaneous leukaemic infiltrations in a patient with previously undiagnosed myelodysplastic syndrome.
Clinical and experimental dermatology 2004;29(5):468-70.
2004: Jan Ehrchen; Anca Sindrilaru; Stephan Grabbe; Frank Schönlau; Christian Schlesiger; Clemens Sorg; Karin Scharffetter-Kochanek; Cord Sunderkötter
Senescent BALB/c mice are able to develop resistance to Leishmania major infection.
Infection and immunity 2004;72(9):5106-14.
2004: C Ozdemir; Lars Alexander Schneider; T Weiss; Karin Scharffetter-Kochanek
[Symmetric nodules over the lateral malleoli of a Turkish patient].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2004;55(8):757-8.
2004: Lars Alexander Schneider; C Ozdemir; Ralf Hinrichs; Karin Scharffetter-Kochanek
[Pruritic nodules in an 81-year-old patient].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2004;55(7):664-6.
2004: Martin Hafner; Jutta Wenk; Arianna Nenci; Manolis Pasparakis; Karin Scharffetter-Kochanek; Neil Smyth; Thorsten Peters; Daniel Kess; Olaf Holtkötter; Pierre Shephard; Jeffrey E Kudlow; Hans Smola; Ingo Haase; Angela Schippers; Thomas Krieg; Werner Muller
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein.
Genesis (New York, N.Y. : 2000) 2004;38(4):176-81.
2004: Margit A Huber; Karin Kunzi-Rapp; Gyde Staib; Karin Scharffetter-Kochanek
Management of refractory early-stage cutaneous T-cell lymphoma (mycosis fungoides) with a combination of oral bexarotene and psoralen plus ultraviolet bath therapy.
Journal of the American Academy of Dermatology 2004;50(3):475-6.
2004: K Welt; S Ott; J M Weiss; Karin Scharffetter-Kochanek
[Painful symmetrical ankle ulcerations. A 73-year old patient with chronic myeloid leukemia].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2004;55(2):190-3.
2004: Julia Maetzke; Ralf Hinrichs; Gyde Staib; Karin Scharffetter-Kochanek
Fondaparinux as a novel therapeutic alternative in a patient with heparin allergy.
Allergy 2004;59(2):237-8.
2004: Dorothee Eich; Karin Scharffetter-Kochanek; Julia Weihrauch; Thomas Krieg; Nicolas Hunzelmann
Calcinosis of the cutis and subcutis: an unusual nonimmunologic adverse reaction to subcutaneous injections of low-molecular-weight calcium-containing heparins.
Journal of the American Academy of Dermatology 2004;50(2):210-4.
2004: J Rampf; Andreas Essig; Ralf Hinrichs; M Merkel; Karin Scharffetter-Kochanek; Cord Sunderkötter
Lymphogranuloma venereum - a rare cause of genital ulcers in central Europe.
Dermatology (Basel, Switzerland) 2004;209(3):230-2.
2004: Sabine A Eming; Susanne Theile-Ochel; Claus Casper; Thomas Krieg; Karin Scharffetter-Kochanek; Nicolas Hunzelmann
Panniculitis induced by specific venom immunotherapy.
Dermatology (Basel, Switzerland) 2004;209(1):62-3.
2003: Daniel Kess; Thorsten Peters; Jan Zamek; Claudia Wickenhauser; Samir Tawadros; Karin Loser; Georg Varga; Stephan Grabbe; Roswitha Nischt; Cord Sunderkötter; Werner Muller; Thomas Krieg; Karin Scharffetter-Kochanek
CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5697-706.
2003: Joachim Dissemond; Lars Alexander Schneider; Meinhard Wlaschek; Tilmann C Brauns; Manfred Goos; Karin Scharffetter-Kochanek
The lazaroid tirilazad is a new inhibitor of direct and indirect UVA-induced lipid peroxidation in human dermal fibroblasts.
Archives of dermatological research 2003;295(7):287-92.
2003: Meinhard Wlaschek; Wenjian Ma; Pidder Jansen-Dürr; Karin Scharffetter-Kochanek
Photoaging as a consequence of natural and therapeutic ultraviolet irradiation--studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts.
Experimental gerontology 2003;38(11-12):1265-70.
2003: Wenjian Ma; Christina Hommel; Peter Brenneisen; Thorsten Peters; N Smit; J Sedivy; Karin Scharffetter-Kochanek; Meinhard Wlaschek
Long-term growth arrest of PUVA-treated fibroblasts in G2/M in the absence of p16(INK4a) p21(CIP1) or p53.
Experimental dermatology 2003;12(5):629-37.
2003: Joachim Dissemond; Tatjana K Weimann; Lars Alexander Schneider; Achim Schneeberger; Karin Scharffetter-Kochanek; Manfred Goos; Stephan N Wagner
Activated neutrophils exert antitumor activity against human melanoma cells: reactive oxygen species-induced mechanisms and their modulation by granulocyte-macrophage-colony-stimulating factor.
The Journal of investigative dermatology 2003;121(4):936-8.
2003: C Ozdemir; Lars Alexander Schneider; Ralf Hinrichs; Gyde Staib; Lutz Weber; J M Weiss; Karin Scharffetter-Kochanek
[Allergic contact dermatitis to common ivy (Hedera helix L.)].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2003;54(10):966-9.
2003: Joachim Dissemond; Lars Alexander Schneider; Peter Brenneisen; K Briviba; Jutta Wenk; Meinhard Wlaschek; Karin Scharffetter-Kochanek
Protective and determining factors for the overall lipid peroxidation in ultraviolet A1-irradiated fibroblasts: in vitro and in vivo investigations.
The British journal of dermatology 2003;149(2):341-9.
2003: Lars Alexander Schneider; Meinhard Wlaschek; Karin Scharffetter-Kochanek
[Skin aging--clinical aspects and pathogenesis].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(3):223-32; quiz 233-4.
2003: Pamela Weinmann; Karin Scharffetter-Kochanek; S Bradley Forlow; Thorsten Peters; Barbara Walzog
A role for apoptosis in the control of neutrophil homeostasis in the circulation: insights from CD18-deficient mice.
Blood 2003;101(2):739-46.
2003: Peter Brenneisen; Ralf Blaudschun; Jens Gille; Lars Schneider; Ralf Hinrichs; Meinhard Wlaschek; Sabine A Eming; Karin Scharffetter-Kochanek
Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes.
The Biochemical journal 2003;369(Pt 2):341-9.
2003: Karin Scharffetter-Kochanek; Jutta Schüller; Christian Meewes; Ralf Hinrichs; Dorothee Eich; Sabine A Eming; Jutta Wenk; Meinhard Wlaschek
[Chronic venous venous ulcus cruris. Pathogenesis and the significance of "aggressive micro-milieus"].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(1):58-67; quiz 68.
2002: Dorothee Eich; Karin Scharffetter-Kochanek; Hans Theodor Eich; Iliana Tantcheva-Poor; Thomas Krieg
Acral erythrodysesthesia syndrome caused by intravenous infusion of docetaxel in breast cancer.
American journal of clinical oncology 2002;25(6):599-602.
2002: Peter Brenneisen; Helmut Sies; Karin Scharffetter-Kochanek
Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events.
Annals of the New York Academy of Sciences 2002;973():31-43.
2002: Lale Naderi-Hachtroudi; Thorsten Peters; Peter Brenneisen; Christian Meewes; Christina Hommel; Ziba Razi-Wolf; Lars Alexander Schneider; Jutta Schüller; Meinhard Wlaschek; Karin Scharffetter-Kochanek
Induction of manganese superoxide dismutase in human dermal fibroblasts: a UV-B-mediated paracrine mechanism with the release of epidermal interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor alpha.
Archives of dermatology 2002;138(11):1473-9.
2002: Ralf Hinrichs; Oliver Fricke; Rengin Tütüncü; Nicolas Hunzelmann; Thomas Krieg; Karin Scharffetter-Kochanek
A patient with hyper-IgE syndrome: a multisystem disorder.
Journal of the American Academy of Dermatology 2002;47(5 Suppl):S268-9.
2002: Wenjian Ma; Meinhard Wlaschek; Christina Hommel; Lars Alexander Schneider; Karin Scharffetter-Kochanek
Psoralen plus UVA (PUVA) induced premature senescence as a model for stress-induced premature senescence.
Experimental gerontology 2002;37(10-11):1197-201.
2002: Ralf Hinrichs; Nicolas Hunzelmann; Andreas Ritzkowsky; T M Zollner; Thomas Krieg; Karin Scharffetter-Kochanek
Caffeine hypersensitivity.
Allergy 2002;57(9):859-60.
2002: Peter Brenneisen; Meinhard Wlaschek; Edith Schwamborn; Lars Alexander Schneider; Wenjian Ma; Helmut Sies; Karin Scharffetter-Kochanek
Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts.
The Biochemical journal 2002;365(Pt 1):31-40.
2002: Ralf Blaudschun; Cord Sunderkötter; Peter Brenneisen; Ralf Hinrichs; Thorsten Peters; L Schneider; Ziba Razi-Wolf; Nicolas Hunzelmann; Karin Scharffetter-Kochanek
Vascular endothelial growth factor causally contributes to the angiogenic response upon ultraviolet B irradiation in vivo.
The British journal of dermatology 2002;146(4):581-7.
2002: Wenjian Ma; Meinhard Wlaschek; Peter Brenneisen; Lars Alexander Schneider; Christina Hommel; Christine Hellweg; Heinrich Sauer; Maria Wartenberg; Gernot Herrmann; Christian Meewes; Petra Boukamp; Karin Scharffetter-Kochanek
Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation.
Experimental cell research 2002;274(2):299-309.
2002: Stephan Grabbe; Georg Varga; Stefan Beissert; Meike Steinert; Gunther Pendl; Stephan Seeliger; Wilhelm Bloch; Thorsten Peters; Thomas Schwarz; Cord Sunderkötter; Karin Scharffetter-Kochanek
Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells.
The Journal of clinical investigation 2002;109(2):183-92.
2002: Christopher Sacher; Andrea Rubbert; Cathrin König; Karin Scharffetter-Kochanek; Thomas Krieg; Nicolas Hunzelmann
Treatment of recalcitrant cicatricial pemphigoid with the tumor necrosis factor alpha antagonist etanercept.
Journal of the American Academy of Dermatology 2002;46(1):113-5.
2001: Wenjian Ma; Meinhard Wlaschek; I Tantcheva-Poór; Lars Alexander Schneider; L Naderi; Ziba Razi-Wolf; Jutta Schüller; Karin Scharffetter-Kochanek
Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue.
Clinical and experimental dermatology 2001;26(7):592-9.
2001: Karin Scharffetter-Kochanek
Skin aging.
Clinical and experimental dermatology 2001;26(7):561.
2001: Meinhard Wlaschek; I Tantcheva-Poór; L Naderi; Wenjian Ma; Lars Alexander Schneider; Ziba Razi-Wolf; Jutta Schüller; Karin Scharffetter-Kochanek
Solar UV irradiation and dermal photoaging.
Journal of photochemistry and photobiology. B, Biology 2001;63(1-3):41-51.
2001: A Jöckel; R M Kopner; Claus Casper; C Mauch; Karin Scharffetter-Kochanek; Nicolas Hunzelmann
[Persistent vulvar edema].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2001;52(8):743-5.
2001: Ralf Hinrichs; Andreas Ritzkowsky; Nicolas Hunzelmann; Thomas Krieg; Karin Scharffetter-Kochanek
Rofecoxib as an alternative in aspirin hypersensitivity.
Allergy 2001;56(8):789.
2001: I Tantcheva-Poór; M Servera-Llaneras; Karin Scharffetter-Kochanek; Uwe Fuhr
Liver cytochrome P450 CYP1A2 is markedly inhibited by systemic but not by bath PUVA in dermatological patients.
The British journal of dermatology 2001;144(6):1127-32.
2001: Jutta Wenk; A Foitzik; V Achterberg; A Sabiwalsky; Joachim Dissemond; Christian Meewes; A Reitz; Peter Brenneisen; Meinhard Wlaschek; W Meyer-Ingold; Karin Scharffetter-Kochanek
Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept.
The Journal of investigative dermatology 2001;116(6):833-9.
2001: Peter Kurschat; A Rubbert; A Poswig; Karin Scharffetter-Kochanek; Thomas Krieg; Nicolas Hunzelmann
Treatment of psoriatic arthritis with etanercept.
Journal of the American Academy of Dermatology 2001;44(6):1052.
2001: Christian Meewes; Peter Brenneisen; Jutta Wenk; L Kuhr; Wenjian Ma; J Alikoski; A Poswig; Thomas Krieg; Karin Scharffetter-Kochanek
Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity.
Free radical biology & medicine 2001;30(3):238-47.
2001: K Hartmann; N Hani; R Hinrichs; Nicolas Hunzelmann; Karin Scharffetter-Kochanek
Successful sulfasalazine treatment of severe chronic idiopathic urticaria associated with pressure urticaria.
Acta dermato-venereologica 2001;81(1):71.
2001: Thomas Willeke; Karin Scharffetter-Kochanek; P Gaehtgens; Barbara Walzog
A role for beta2 integrin (CD11/CD18)-mediated tyrosine signaling in extravasation of human polymorphonuclear neutrophils.
Biorheology 2001;38(2-3):89-100.
2001: Christopher Sacher; Cathrin König; Karin Scharffetter-Kochanek; Thomas Krieg; Nicolas Hunzelmann
Bullous pemphigoid in a patient treated with UVA-1 phototherapy for disseminated morphea.
Dermatology (Basel, Switzerland) 2001;202(1):54-7.
2001: Jutta Wenk; Peter Brenneisen; Christian Meewes; Meinhard Wlaschek; Thorsten Peters; Ralf Blaudschun; Wenjian Ma; L Kuhr; L Schneider; Karin Scharffetter-Kochanek
UV-induced oxidative stress and photoaging.
Current problems in dermatology 2001;29():83-94.
2000: Meinhard Wlaschek; Christina Hommel; Jutta Wenk; Peter Brenneisen; Wenjian Ma; Gernot Herrmann; Karin Scharffetter-Kochanek
Isolation and identification of psoralen plus ultraviolet A (PUVA)-induced genes in human dermal fibroblasts by polymerase chain reaction-based subtractive hybridization.
The Journal of investigative dermatology 2000;115(5):909-13.
2000: Peter Kurschat; A Kröger; Karin Scharffetter-Kochanek; Nicolas Hunzelmann
Acquired reactive perforating collagenosis triggered by scabies infection.
Acta dermato-venereologica 2000;80(5):384-5.
2000: Frank Schönlau; Karin Scharffetter-Kochanek; Stephan Grabbe; B Pietz; Clemens Sorg; Cord Sunderkötter
In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response.
European journal of immunology 2000;30(9):2729-40.
2000: Christian Meewes; A Poswig; Joachim Dissemond; Peter Brenneisen; Karin Scharffetter-Kochanek
Adaptive antioxidant defence in human dermal fibroblasts.
The British journal of dermatology 2000;143(3):662-3.
2000: Meinhard Wlaschek; Jutta Wenk; Peter Brenneisen; Christina Hommel; Wenjian Ma; Gernot Herrmann; Karin Scharffetter-Kochanek
PCR-based subtractive hybridization identifies repressed genes in growth-arrested human dermal fibroblasts following combined treatment with 8-methoxypsoralen and UVA irradiation (PUVA).
Experimental gerontology 2000;35(5):573-81.
2000: Thomas Willeke; S Behrens; Karin Scharffetter-Kochanek; P Gaehtgens; Barbara Walzog
Beta2 integrin (CD11/CD18)-mediated signaling involves tyrosine phosphorylation of c-Cbl in human neutrophils.
Journal of leukocyte biology 2000;68(2):284-92.
2000: Ralf Blaudschun; Peter Brenneisen; Meinhard Wlaschek; Christian Meewes; Karin Scharffetter-Kochanek
The first peak of the UVB irradiation-dependent biphasic induction of vascular endothelial growth factor (VEGF) is due to phosphorylation of the epidermal growth factor receptor and independent of autocrine transforming growth factor alpha.
FEBS letters 2000;474(2-3):195-200.
2000: A Poswig; Ralf Hinrichs; Mosaad Megahed; Nicolas Hunzelmann; K Kirchberg; Peter Brenneisen; Thomas Krieg; Karin Scharffetter-Kochanek
Discrete papular mucinosis-a rare subtype of lichen myxoedematosus.
Clinical and experimental dermatology 2000;25(4):289-92.
2000: N Hani; K Hartmann; Claus Casper; T Peters; L A Schneider; Nicolas Hunzelmann; Karin Scharffetter-Kochanek
Improvement of cold urticaria by treatment with the leukotriene receptor antagonist montelukast.
Acta dermato-venereologica 2000;80(3):229.
2000: C M Neess; Ralf Hinrichs; Joachim Dissemond; Gernot Herrmann; A Poswig; M Servera-Llanras; Nicolas Hunzelmann; Peter Brenneisen; Christian Meewes; Thomas Krieg; Karin Scharffetter-Kochanek
Treatment of pruritus by capsaicin in a patient with pityriasis rubra pilaris receiving RE-PUVA therapy.
Clinical and experimental dermatology 2000;25(3):209-11.
2000: Karin Scharffetter-Kochanek; Peter Brenneisen; Jutta Wenk; Gernot Herrmann; Wenjian Ma; L Kuhr; Christian Meewes; Meinhard Wlaschek
Photoaging of the skin from phenotype to mechanisms.
Experimental gerontology 2000;35(3):307-16.
2000: Peter Brenneisen; Jutta Wenk; Meinhard Wlaschek; Thomas Krieg; Karin Scharffetter-Kochanek
Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts.
The Journal of biological chemistry 2000;275(6):4336-44.
2000: A Kruppa; B Korge; J Lasch; Karin Scharffetter-Kochanek; Nicolas Hunzelmann
Successful treatment of Hailey-Hailey disease with a scanned carbon dioxide laser.
Acta dermato-venereologica 2000;80(1):53-4.
2000: J Gillner; K Kirchberg; Bernhard P Korge; Nicolas Hunzelmann; Thomas Krieg; Karin Scharffetter-Kochanek
[Cutaneous metastases from a leiomyosarcoma of the testicular tunica albuginea].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(1):41-5.
1999: Nicolas Hunzelmann; R Kopner; N Hani; Karin Scharffetter-Kochanek
Immediate-type reactions to cisatracurium.
Allergy 1999;54(11):1227-8.
1999: Ralf Hinrichs; K Kirchberg; Joachim Dissemond; J D Hoppe; Peter Brenneisen; Thomas Krieg; Karin Scharffetter-Kochanek
Carcinoma erysipeloides of the facial skin in a patient with metastatic breast cancer.
The British journal of dermatology 1999;141(5):940-1.
1999: Peter Brenneisen; Jutta Wenk; Meinhard Wlaschek; Ralf Blaudschun; Karin Scharffetter-Kochanek
A newly adapted pulsed-field gel electrophoresis technique allows to detect distinct types of DNA damage at low frequencies in human dermal fibroblasts upon exposure to non-toxic H2O2 concentrations.
Free radical research 1999;31(5):405-18.
1999: Barbara Walzog; Pamela Weinmann; F Jeblonski; Karin Scharffetter-Kochanek; Kurt Bommert; P Gaehtgens
A role for beta(2) integrins (CD11/CD18) in the regulation of cytokine gene expression of polymorphonuclear neutrophils during the inflammatory response.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(13):1855-65.
1999: Jutta Wenk; Peter Brenneisen; Meinhard Wlaschek; A Poswig; K Briviba; T D Oberley; Karin Scharffetter-Kochanek
Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1.
The Journal of biological chemistry 1999;274(36):25869-76.
1999: Claudia Wickenhauser; Peter Borchmann; Volker Diehl; Karin Scharffetter-Kochanek
Development of IgG lambda multiple myeloma in a patient with cutaneous CD30+ anaplastic T-cell lymphoma.
Leukemia & lymphoma 1999;35(1-2):201-6.
1999: C Casper; Karin Scharffetter-Kochanek; Heribert Bohlen; R P Linke; T Krieg; Nicolas Hunzelmann
Light chain multiple myeloma with peripheral leucocytosis presenting as scleroderma amyloidosum of the Alambda-type.
The British journal of dermatology 1999;140(6):1172-4.
1999: Barbara Walzog; Karin Scharffetter-Kochanek; P Gaehtgens
Impairment of neutrophil emigration in CD18-null mice.
The American journal of physiology 1999;276(5 Pt 1):G1125-30.
1999: Peter Brenneisen; Meinhard Wlaschek; Jutta Wenk; Ralf Blaudschun; Ralf Hinrichs; Joachim Dissemond; Thomas Krieg; Karin Scharffetter-Kochanek
Ultraviolet-B induction of interstitial collagenase and stromelyin-1 occurs in human dermal fibroblasts via an autocrine interleukin-6-dependent loop.
FEBS letters 1999;449(1):36-40.
1999: A Poswig; Jutta Wenk; Peter Brenneisen; Meinhard Wlaschek; Christina Hommel; G Quel; K Faisst; Joachim Dissemond; K Briviba; Thomas Krieg; Karin Scharffetter-Kochanek
Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation.
The Journal of investigative dermatology 1999;112(1):13-8.
1998: T Peters; N Hani; K Kirchberg; H Gold; Nicolas Hunzelmann; Karin Scharffetter-Kochanek
Occupational contact sensitivity to aluminium in a machine construction plant worker.
Contact dermatitis 1998;39(6):322-3.
1998: Peter Brenneisen; Ralf Blaudschun; M Bernards; Jutta Wenk; Meinhard Wlaschek; W Meyer-Ingold; Matthias Schauen; Thomas Krieg; Karin Scharffetter-Kochanek
Increased temperature: a potentially important side-effect of ultraviolet radiation treatment leading to induction of interstitial collagenase/matrix metalloproteinase-1.
The British journal of dermatology 1998;139(3):537-9.
1998: Nicolas Hunzelmann; H Gold; Karin Scharffetter-Kochanek
Concomitant sensitization to high and low molecular-weight heparins, heparinoid and pentosanpolysulfate.
Contact dermatitis 1998;39(2):88-9.
1998: H Smola; A Kruppa; Nicolas Hunzelmann; Thomas Krieg; Karin Scharffetter-Kochanek
Identification of dimenhydrinate as the causative agent in fixed drug eruption using patch-testing in previously affected skin.
The British journal of dermatology 1998;138(5):920-1.
1998: Nicolas Hunzelmann; Karin Scharffetter-Kochanek; CM Hager; Thomas Krieg
Management of localized scleroderma.
Seminars in cutaneous medicine and surgery 1998;17(1):34-40.
1998: Gernot Herrmann; Peter Brenneisen; Meinhard Wlaschek; Jutta Wenk; K Faisst; G Quel; Christina Hommel; G Goerz; Thomas Ruzicka; Thomas Krieg; Helmut Sies; Karin Scharffetter-Kochanek
Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence.
Journal of cell science 1998;111 ( Pt 6)():759-67.
1998: Peter Brenneisen; Jutta Wenk; Lars-Oliver Klotz; Meinhard Wlaschek; K Briviba; Thomas Krieg; H Sies; Karin Scharffetter-Kochanek
Central role of Ferrous/Ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (matrix-degrading metalloprotease (MMP)-1) and stromelysin-1 (MMP-3) mRNA levels in cultured human dermal fibroblasts.
The Journal of biological chemistry 1998;273(9):5279-87.
1998: CM Hager; H A Sobhi; Nicolas Hunzelmann; Claudia Wickenhauser; R Scharenberg; Thomas Krieg; Karin Scharffetter-Kochanek
Bath-PUVA therapy in three patients with scleredema adultorum.
Journal of the American Academy of Dermatology 1998;38(2 Pt 1):240-2.
1998: A Kruppa; Karin Scharffetter-Kochanek; Thomas Krieg; Nicolas Hunzelmann
Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin.
Dermatology (Basel, Switzerland) 1998;196(3):335-6.
1997: Karin Scharffetter-Kochanek; Meinhard Wlaschek; Peter Brenneisen; Matthias Schauen; Ralf Blaudschun; Jutta Wenk
UV-induced reactive oxygen species in photocarcinogenesis and photoaging.
Biological chemistry 1997;378(11):1247-57.
1997: Meinhard Wlaschek; D Peus; V Achterberg; W Meyer-Ingold; Karin Scharffetter-Kochanek
Protease inhibitors protect growth factor activity in chronic wounds.
The British journal of dermatology 1997;137(4):646.
1997: Meinhard Wlaschek; Jutta Wenk; Peter Brenneisen; K Briviba; A Schwarz; H Sies; Karin Scharffetter-Kochanek
Singlet oxygen is an early intermediate in cytokine-dependent ultraviolet-A induction of interstitial collagenase in human dermal fibroblasts in vitro.
FEBS letters 1997;413(2):239-42.
1997: Peter Brenneisen; K Briviba; Meinhard Wlaschek; Jutta Wenk; Karin Scharffetter-Kochanek
Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts.
Free radical biology & medicine 1997;22(3):515-24.
1996: Peter Brenneisen; J Oh; Meinhard Wlaschek; Jutta Wenk; K Briviba; Christina Hommel; G Herrmann; Helmut Sies; Karin Scharffetter-Kochanek
Ultraviolet B wavelength dependence for the regulation of two major matrix-metalloproteinases and their inhibitor TIMP-1 in human dermal fibroblasts.
Photochemistry and photobiology 1996;64(5):877-85.
1996: Peter Brenneisen; J Oh; Meinhard Wlaschek; Jutta Wenk; K Briviba; Christina Hommel; G Herrmann; Helmut Sies; Karin Scharffetter-Kochanek
Ultraviolet B wavelength dependence for the regulation of two major matrix-metalloproteinases and their inhibitor TIMP-1 in human dermal fibroblasts.
Photochemistry and photobiology 1996;64(4):649-57.
1996: G Herrmann; Meinhard Wlaschek; K Bolsen; K Prenzel; G Goerz; Karin Scharffetter-Kochanek
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
The Journal of investigative dermatology 1996;107(3):398-403.
1995: M Brunner; E Vardarman; R Goldermann; G Goerz; D Niederau; Hans F Merk; Karin Scharffetter-Kochanek
Toxic epidermal necrolysis (Lyell syndrome) following famotidine administration.
The British journal of dermatology 1995;133(5):814-5.
1995: K Kirchberg; T S Lange; E C Klein; H Jungtäubl; G Heinen; W Meyer-Ingold; Karin Scharffetter-Kochanek
Induction of beta 1 integrin synthesis by recombinant platelet-derived growth factor (PDGF-AB) correlates with an enhanced migratory response of human dermal fibroblasts to various extracellular matrix proteins.
Experimental cell research 1995;220(1):29-35.
1995: D Peus; H Jungtäubl; S Knaub; A Leuker; K Gerecht; R Ostendorf; W Meyer-Ingold; Meinhard Wlaschek; Thomas Krieg; T Ruzicka; Karin Scharffetter-Kochanek
Localization of platelet-derived growth factor receptor subunit expression in chronic venous leg ulcers.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1995;3(3):265-72.
1995: M Kiss; Meinhard Wlaschek; Peter Brenneisen; G Michel; Christina Hommel; T S Lange; D Peus; Lajos Kemeny; A Dobozy; Karin Scharffetter-Kochanek
Alpha-melanocyte stimulating hormone induces collagenase/matrix metalloproteinase-1 in human dermal fibroblasts.
Biological chemistry Hoppe-Seyler 1995;376(7):425-30.
1995: T S Lange; J Kirchberg; Anja-Katrin Bielinsky; A Leuker; I Bank; T Ruzicka; Karin Scharffetter-Kochanek
Divalent cations (Mg2+, Ca2+) differentially influence the beta 1 integrin-mediated migration of human fibroblasts and keratinocytes to different extracellular matrix proteins.
Experimental dermatology 1995;4(3):130-7.
1995: Karin Scharffetter-Kochanek; R Goldermann; P Lehmann; E Hölzle; G Goerz
PUVA therapy in disabling pansclerotic morphoea of children.
The British journal of dermatology 1995;132(5):830-1.
1995: Meinhard Wlaschek; K Briviba; G P Stricklin; Helmut Sies; Karin Scharffetter-Kochanek
Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase.
The Journal of investigative dermatology 1995;104(2):194-8.
1994: Mosaad Megahed; U Hofmann; Karin Scharffetter-Kochanek; Thomas Ruzicka
[Amelanotic polypoid malignant melanoma of the balloon cell type].
Der Pathologe 1994;15(6):350-3.
1994: Mosaad Megahed; S Reinauer; Karin Scharffetter-Kochanek; P Milde; Erhard Hölzle; G Goerz; Thomas Ruzicka
Acquired relapsing self-healing Blaschko dermatitis.
Journal of the American Academy of Dermatology 1994;31(5 Pt 2):849-52.
1994: T S Lange; Anja-Katrin Bielinsky; K Kirchberg; I Bank; K Herrmann; Thomas Krieg; Karin Scharffetter-Kochanek
Mg2+ and Ca2+ differentially regulate beta 1 integrin-mediated adhesion of dermal fibroblasts and keratinocytes to various extracellular matrix proteins.
Experimental cell research 1994;214(1):381-8.
1994: Meinhard Wlaschek; G Heinen; A Poswig; A Schwarz; Thomas Krieg; Karin Scharffetter-Kochanek
UVA-induced autocrine stimulation of fibroblast-derived collagenase/MMP-1 by interrelated loops of interleukin-1 and interleukin-6.
Photochemistry and photobiology 1994;59(5):550-6.
1994: Mosaad Megahed; Karin Scharffetter-Kochanek
Epidermolysis bullosa acquisita--successful treatment with colchicine.
Archives of dermatological research 1994;286(1):35-46.
1993: Karin Scharffetter-Kochanek; Meinhard Wlaschek; K Briviba; Helmut Sies
Singlet oxygen induces collagenase expression in human skin fibroblasts.
FEBS letters 1993;331(3):304-6.
1993: Meinhard Wlaschek; K Bolsen; G Herrmann; A Schwarz; F Wilmroth; P C Heinrich; G Goerz; Karin Scharffetter-Kochanek
UVA-induced autocrine stimulation of fibroblast-derived-collagenase by IL-6: a possible mechanism in dermal photodamage?
The Journal of investigative dermatology 1993;101(2):164-8.
1993: Mosaad Megahed; Karin Scharffetter-Kochanek
Acantholytic acanthoma.
The American Journal of dermatopathology 1993;15(3):283-5.
1993: R Goldermann; E Vardarman; Norbert J Neumann; Karin Scharffetter-Kochanek; G Goerz
Contact dermatitis from UV-A and UV-B filters in a patient with erythropoietic protoporphyria.
Contact dermatitis 1993;28(5):300-1.
1993: G Herrmann; Meinhard Wlaschek; T S Lange; K Prenzel; G Goerz; Karin Scharffetter-Kochanek
UVA irradiation stimulates the synthesis of various matrix-metalloproteinases (MMPs) in cultured human fibroblasts.
Experimental dermatology 1993;2(2):92-7.
1992: R Goldermann; Karin Scharffetter-Kochanek; M Brunner; H Merk; G Goerz
3 cases of contact dermatitis from alkylammonium amidobenzoate (Osmaron B).
Contact dermatitis 1992;27(5):337-9.
1992: Karin Scharffetter-Kochanek; CE Klein; G Heinen; Cornelia Mauch; T Schaefer; B C Adelmann-Grill; G Goerz; N E Fusenig; Thomas Krieg; G Plewig
Migration of a human keratinocyte cell line (HACAT) to interstitial collagen type I is mediated by the alpha 2 beta 1-integrin receptor.
The Journal of investigative dermatology 1992;98(1):3-11.