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Manfred Schartl

Research Profile

Living Beings

Chemicals & Drugs

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Disorders

Melanoma

Genes & Molecular Sequences

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Evolution, Molecular

Physiology

Gene Expression Regulation, Developmental

Anatomy

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Fluorescence In Situ Hybridization

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Publications

TOP 3
J A G C Laisney; Thomas D Mueller; Manfred Schartl; Svenja Meierjohann
Hyperactivation of constitutively dimerized oncogenic EGF receptors by autocrine loops.
Manfred Schartl; Steve Searle; Yingjia Shen; Jean-Nicolas Volff; Ronald B Walter; Richard K Wilson; Angel Amores; Angelo Bisazza; Jeffrey Boore; Ingo Braasch; Julian Catchen; Domitille Chalopin; Susan Fuerstenberg; Tzintzuni Garcia; Ladeana Hillier; Klaus-Peter Lesch; Patrick J Minx; John H Postlethwait; Wesley C Warren
The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits.
Yingjia Shen; Wes Warren; Ion Beldorth; Mikki Boswell; William A Cresko; Tzintzuni Garcia; Vagmita Pabuwal; Amanda Pasquali; Manfred Schartl; Ronald B Walter
Alternative strategies for development of a reference transcriptome for quantification of allele specific expression in organisms having sparse genomic resources.

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All Publications

2013: J A G C Laisney; Thomas D Mueller; Manfred Schartl; Svenja Meierjohann
Hyperactivation of constitutively dimerized oncogenic EGF receptors by autocrine loops.
Oncogene 2013;32(19):2403-11.
2013: Manfred Schartl; Steve Searle; Yingjia Shen; Jean-Nicolas Volff; Ronald B Walter; Richard K Wilson; Angel Amores; Angelo Bisazza; Jeffrey Boore; Ingo Braasch; Julian Catchen; Domitille Chalopin; Susan Fuerstenberg; Tzintzuni Garcia; Ladeana Hillier; Klaus-Peter Lesch; Patrick J Minx; John H Postlethwait; Wesley C Warren
The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits.
Nature genetics 2013;45(5):567-72.
2013: Yingjia Shen; Wes Warren; Ion Beldorth; Mikki Boswell; William A Cresko; Tzintzuni Garcia; Vagmita Pabuwal; Amanda Pasquali; Manfred Schartl; Ronald B Walter
Alternative strategies for development of a reference transcriptome for quantification of allele specific expression in organisms having sparse genomic resources.
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2013;8(1):11-6.
2013: Ni Hong; Bei Ping He; Manfred Schartl; Yunhan Hong
Medaka embryonic stem cells are capable of generating entire organs and embryo-like miniatures.
Stem cells and development 2013;22(5):750-7.
2013: Mariko Forconi; Marco Gerdol; Daisy M Makapedua; Ettore Olmo; Alberto Pallavicini; Giuseppe Scapigliati; Marco Barucca; Maria Assunta Biscotti; Francesco Buonocore; Adriana Canapa; Teresa Capriglione; Gianluca De Moro; Anna M Fausto; Manfred Schartl
Characterization of sex determination and sex differentiation genes in latimeria.
PloS one 2013;8(4):e56006.
2013: Daniela Schul; Janine Regneri; Manfred Schartl; Alexandra Schmitt; Toni Wagner
Bursted BMP triggered receptor kinase activity drives Smad1 mediated long-term target gene oscillation in c2c12 cells.
PloS one 2013;8(4):e59442.
2013: Yan Yan; Songlin Chen; Tiansheng Chen; Guijun Guan; Ni Hong; Chang-Ming Li; Mingyou Li; Yongkang Qiao; Manfred Schartl; Tiansu Wang; Yunhan Hong
p53 gene targeting by homologous recombination in fish ES cells.
PloS one 2013;8(3):e59400.
2013: Ji Hyoun Kang; Manfred Schartl; Ronald B Walter; Axel Meyer
Comprehensive phylogenetic analysis of all species of swordtails and platies (Pisces: Genus Xiphophorus) uncovers a hybrid origin of a swordtail fish, Xiphophorus monticolus, and demonstrates that the sexually selected sword originated in the ancestral lineage of the genus, but was lost again secondarily.
BMC evolutionary biology 2013;13():25.
2012: Luciana A Menescal; Daniel Liedtke; Cornelia Schmidt; Manfred Schartl
Liver hyperplasia after tamoxifen induction of Myc in a transgenic medaka model.
Disease models & mechanisms 2012;5(4):492-502.
2012: Kathrin P Lampert; Benjamin P Ngatunga; Katrin Blassmann; Hans Fricke; Karen Hissmann; Jürgen Schauer; Manfred Schartl
Population divergence in East African coelacanths.
Current biology : CB 2012;22(11):R439-40.
2012: Matthias Stöck; Jana Ustinova; Caroline Betto-Colliard; Craig Moritz; Manfred Schartl; Nicolas Perrin
Simultaneous Mendelian and clonal genome transmission in a sexually reproducing, all-triploid vertebrate.
Proceedings. Biological sciences / The Royal Society 2012;279(1732):1293-9.
2012: Eva C Thoma; Toni Wagner; Katja Maurus; Manfred Schartl
Parallel differentiation of embryonic stem cells into different cell types by a single gene-based differentiation system.
Cellular reprogramming 2012;14(2):106-11.
2012: Zhen Li; Svenja Meierjohann; Manfred Schartl; Jan M Spitsbergen; Zhiqiang Zeng; Huiqing Zhan; Xiaoqian Huang; Caixia Li; Zhiyuan Gong
Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish.
Journal of hepatology 2012;56(2):419-25.
2012: Astrid Böhne; Amandine Darras; Delphine Galiana-Arnoux; Manfred Schartl; Cornelia Schmidt; Qingchun Zhou; Jean-Nicolas Volff
Zisupton--a novel superfamily of DNA transposable elements recently active in fish.
Molecular biology and evolution 2012;29(2):631-45.
2012: Eva C Thoma; Erhard Wischmeyer; Katja Maurus; Nils Offen; Manfred Schartl; Anna-Leena Sirén; Toni Wagner
Ectopic expression of neurogenin 2 alone is sufficient to induce differentiation of embryonic stem cells into mature neurons.
PloS one 2012;7(6):e38651.
2012: Manfred Schartl; Herman P Spaink; Toni Wagner; Brigitta Wilde; Christiaan V Henkel; Susanne Kneitz; Svenja Meierjohann
Conserved expression signatures between medaka and human pigment cell tumors.
PloS one 2012;7(5):e37880.
2012: T I Garcia; John Postlethwait; Manfred Schartl; Y Shen; Angel Amores; J Catchen; R B Walter
Effects of short read quality and quantity on a de novo vertebrate transcriptome assembly.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2012;155(1):95-101.
2012: Janine Regneri; Manfred Schartl
Expression regulation triggers oncogenicity of xmrk alleles in the Xiphophorus melanoma system.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2012;155(1):71-80.
2012: Yingjia Shen; Jonathan Wagner; Wes Warren; Ziping Zhang; Angel Amores; Ion Beldorth; Julian Catchen; Tzintzuni Garcia; John Postlethwait; Manfred Schartl; Ronald B Walter
Identification of transcriptome SNPs between Xiphophorus lines and species for assessing allele specific gene expression within F₁ interspecies hybrids.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2012;155(1):102-8.
2011: Xinjun He; Amaury Herpin; Manfred Schartl; Toni U Wagner; Yi-Lin Yan; Johann K Eberhart; John H Postlethwait
miR-196 regulates axial patterning and pectoral appendage initiation.
Developmental biology 2011;357(2):463-77.
2011: Amaury Herpin; Manfred Schartl
Sex determination: switch and suppress.
Current biology : CB 2011;21(17):R656-9.
2011: Eva C Thoma; Toni Wagner; Isabell P Weber; Andreas Fischer; Amaury Herpin; Manfred Schartl
Ectopic expression of single transcription factors directs differentiation of a medaka spermatogonial cell line.
Stem cells and development 2011;20(8):1425-38.
2011: Lindsey McFarlane; Terje Svingen; Ingo Braasch; Peter Koopman; Manfred Schartl; Dagmar Wilhelm
Expansion of the Ago gene family in the teleost clade.
Development genes and evolution 2011;221(2):95-104.
2011: Amaury Herpin; Manfred Schartl
Vertebrate sex determination: questioning the hierarchy.
The FEBS journal 2011;278(7):1001.
2011: Amaury Herpin; Manfred Schartl
Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in fish.
The FEBS journal 2011;278(7):1010-9.
2011: Daniel Liedtke; Isabell Erhard; Manfred Schartl
snail gene expression in the medaka, Oryzias latipes.
Gene expression patterns : GEP 2011;11(3-4):181-9.
2011: Isa Matos; Manfred Schartl; Elio Sucena; Rui Gardner; Angela Inácio; Miguel P Machado; Maria Manuela Coelho
Ploidy mosaicism and allele-specific gene expression differences in the allopolyploid Squalius alburnoides.
BMC genetics 2011;12():101.
2011: Dunja K Lamatsch; Michael Schmid; S Schories; V Trifonov; Jörg T Epplen; Manfred Schartl
Isolation of a cancer-associated microchromosome in the sperm-dependent parthenogen Poecilia formosa.
Cytogenetic and genome research 2011;135(2):135-42.
2011: E Elizabeth Patton; Marie E Mathers; Manfred Schartl
Generating and analyzing fish models of melanoma.
Methods in cell biology 2011;105():339-66.
2011: Michael Kraeussling; Toni Wagner; Manfred Schartl
Highly asynchronous and asymmetric cleavage divisions accompany early transcriptional activity in pre-blastula medaka embryos.
PloS one 2011;6(7):e21741.
2010: Matthias Stöck; Kathrin P Lampert; Dirk Möller; Ingo Schlupp; Manfred Schartl
Monophyletic origin of multiple clonal lineages in an asexual fish (Poecilia formosa).
Molecular ecology 2010;19(23):5204-15.
2010: Irene Pala; Manfred Schartl; Miguel Brito; Joana Malta Vacas; Maria Manuela Coelho
Gene expression regulation and lineage evolution: the North and South tale of the hybrid polyploid Squalius alburnoides complex.
Proceedings. Biological sciences / The Royal Society 2010;277(1699):3519-25.
2010: Dunja K Lamatsch; M Stöck; R Fuchs; M Döbler; R Wacker; J Parzefall; I Schlupp; Manfred Schartl
Morphology, testes development and behaviour of unusual triploid males in microchromosome-carrying clones of Poecilia formosa.
Journal of fish biology 2010;77(7):1459-87.
2010: Kathrin P Lampert; Cornelia Schmidt; Petra Fischer; Jean-Nicolas Volff; Carsten Hoffmann; Jenny Muck; Martin J Lohse; Michael J Ryan; Manfred Schartl
Determination of onset of sexual maturation and mating behavior by melanocortin receptor 4 polymorphisms.
Current biology : CB 2010;20(19):1729-34.
2010: Ni Hong; Mingyou Li; Zhiqiang Zeng; Meisheng Yi; Jiaorong Deng; Jianfang Gui; Christoph Winkler; Manfred Schartl; Yunhan Hong
Accessibility of host cell lineages to medaka stem cells depends on genetic background and irradiation of recipient embryos.
Cellular and molecular life sciences : CMLS 2010;67(7):1189-1202.
2010: Matthias Stöck; Jana Ustinova; Dunja K Lamatsch; Manfred Schartl; Nicolas Perrin; Craig Moritz
A vertebrate reproductive system involving three ploidy levels: hybrid origin of triploids in a contact zone of diploid and tetraploid palearctic green toads (Bufo viridis subgroup).
Evolution; international journal of organic evolution 2010;64(4):944-59.
2010: Qingchun Zhou; Ingo Braasch; Alexander Froschauer; Astrid Böhne; Christina Schultheis; Manfred Schartl; Jean-Nicolas Volff
A novel marker for the platyfish (Xiphophorus maculatus) W chromosome is derived from a Polinton transposon.
Journal of genetics and genomics = Yi chuan xue bao 2010;37(3):181-8.
2010: Amaury Herpin; Ingo Braasch; Michael Kraeussling; Cornelia Schmidt; Eva C Thoma; Shuhei Nakamura; Minoru Tanaka; Manfred Schartl
Transcriptional rewiring of the sex determining dmrt1 gene duplicate by transposable elements.
PLoS genetics 2010;6(2):e1000844.
2010: Kathrin P Lampert; Manfred Schartl
A little bit is better than nothing: the incomplete parthenogenesis of salamanders, frogs and fish.
BMC biology 2010;8():78.
2010: Svenja Meierjohann; Anita Hufnagel; Elisabeth Wende; Markus Kleinschmidt; Katarina Wolf; Peter Friedl; Stefan Gaubatz; Manfred Schartl
MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.
Molecular cancer 2010;9():201.
2010: Janka Teutschbein; Johannes M Haydn; Birgit Samans; Michael Krause; Martin Eilers; Manfred Schartl; Svenja Meierjohann
Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins.
BMC cancer 2010;10():386.
2010: Isa Matos; M P Machado; E Sucena; Maria João Collares-Pereira; Manfred Schartl; Maria Manuela Coelho
Evidence for hermaphroditism in the Squalius alburnoides allopolyploid fish complex.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2010;4(3):170-5.
2010: Juliette A G C Laisney; Ingo Braasch; Ronald B Walter; Svenja Meierjohann; Manfred Schartl
Lineage-specific co-evolution of the Egf receptor/ligand signaling system.
BMC evolutionary biology 2010;10():27.
2010: Manfred Schartl; Brigitta Wilde; Juliette A G C Laisney; Yoshihito Taniguchi; Shunichi Takeda; Svenja Meierjohann
A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies.
The Journal of investigative dermatology 2010;130(1):249-58.
2009: Ingo Braasch; Daniel Liedtke; Jean-Nicolas Volff; Manfred Schartl
Pigmentary function and evolution of tyrp1 gene duplicates in fish.
Pigment cell & melanoma research 2009;22(6):839-50.
2009: Astrid Böhne; Christina Schultheis; Delphine Galiana-Arnoux; Alexander Froschauer; Qingchun Zhou; Cornelia Schmidt; Yvonne Selz; Catherine Ozouf-Costaz; Agnès Dettai; Béatrice Segurens; Arnaud Couloux; Sylvie Bernard-Samain; Valérie Barbe; Stefan Chilmonczyk; Frédéric Brunet; Amandine Darras; Marta Tomaszkiewicz; Marie Semon; Manfred Schartl; Jean-Nicolas Volff
Molecular analysis of the sex chromosomes of the platyfish Xiphophorus maculatus: Towards the identification of a new type of master sexual regulator in vertebrates.
Integrative zoology 2009;4(3):277-84.
2009: Amaury Herpin; Manfred Schartl
Molecular mechanisms of sex determination and evolution of the Y-chromosome: insights from the medakafish (Oryzias latipes).
Molecular and cellular endocrinology 2009;306(1-2):51-8.
2009: Katrin Lokaj; Svenja Meierjohann; Claudia Schütz; Janka Teutschbein; Manfred Schartl; Albert Sickmann
Quantitative differential proteome analysis in an animal model for human melanoma.
Journal of proteome research 2009;8(4):1818-27.
2009: Ingo Braasch; Jean-Nicolas Volff; Manfred Schartl
The endothelin system: evolution of vertebrate-specific ligand-receptor interactions by three rounds of genome duplication.
Molecular biology and evolution 2009;26(4):783-99.
2009: Amaury Herpin; Shuhei Nakamura; Toni U Wagner; Shuhei Nakamura; Manfred Schartl
A highly conserved cis-regulatory motif directs differential gonadal synexpression of Dmrt1 transcripts during gonad development.
Nucleic acids research 2009;37(5):1510-20.
2009: Kathrin P Lampert; Petra Fischer; Manfred Schartl
Major histocompatibility complex variability in the clonal Amazon molly, Poecilia formosa: is copy number less important than genotype?
Molecular ecology 2009;18(6):1124-36.
2009: Janka Teutschbein; Manfred Schartl; Svenja Meierjohann
Interaction of Xiphophorus and murine Fyn with focal adhesion kinase.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2009;149(2):168-74.
2009: Ingo Braasch; Frédéric Brunet; Jean-Nicolas Volff; Manfred Schartl
Pigmentation pathway evolution after whole-genome duplication in fish.
Genome biology and evolution 2009;1():479-93.
2009: T Hansmann; Indrajit Nanda; V Volobouev; F Yang; Manfred Schartl; Thomas Haaf; Michael Schmid
Cross-species chromosome painting corroborates microchromosome fusion during karyotype evolution of birds.
Cytogenetic and genome research 2009;126(3):281-304.
2009: Christina Schultheis; A Böhne; Manfred Schartl; Jean-Nicolas Volff; Delphine Galiana-Arnoux
Sex determination diversity and sex chromosome evolution in poeciliid fish.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2009;3(2-3):68-77.
2009: Irene Pala; Manfred Schartl; Sólveig Thorsteinsdóttir; Maria Manuela Coelho
Sex determination in the Squalius alburnoides complex: an initial characterization of sex cascade elements in the context of a hybrid polyploid genome.
PloS one 2009;4(7):e6401.
2009: Kathrin Reichwald; Chris Lauber; Indrajit Nanda; Jeanette Kirschner; Nils Hartmann; Susanne Schories; Ulrike Gausmann; Stefan Taudien; Markus B Schilhabel; Karol Szafranski; Gernot Glöckner; Michael Schmid; Alessandro Cellerino; Manfred Schartl; Christoph Englert; Matthias Platzer
High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research.
Genome biology 2009;10(2):R16.
2009: Nils Klüver; Amaury Herpin; Ingo Braasch; Julia Driessle; Manfred Schartl
Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance.
Developmental biology 2009;325(1):179-88.
2009: Toni Wagner; M Kraeussling; Lev Fedorov; C Reiss; Burkhard Kneitz; Manfred Schartl
STAT3 and SMAD1 signaling in Medaka embryonic stem-like cells and blastula embryos.
Stem cells and development 2009;18(1):151-60.
2008: C Leikam; A Hufnagel; Manfred Schartl; Svenja Meierjohann
Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence.
Oncogene 2008;27(56):7070-82.
2008: Amaury Herpin; Manfred Schartl
Regulatory putsches create new ways of determining sexual development.
EMBO reports 2008;9(10):966-8.
2008: Kathrin P Lampert; Manfred Schartl
The origin and evolution of a unisexual hybrid: Poecilia formosa.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1505):2901-9.
2008: Irene Pala; Maria M Coelho; Manfred Schartl
Dosage compensation by gene-copy silencing in a triploid hybrid fish.
Current biology : CB 2008;18(17):1344-8.
2008: Manfred Schartl
Evolution of Xmrk: an oncogene, but also a speciation gene?
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(9):822-32.
2008: Amaury Herpin; Peter Fischer; Daniel Liedtke; Nils Kluever; Cordula Neuner; erez raz; Manfred Schartl
Sequential SDF1a and b-induced mobility guides Medaka PGC migration.
Developmental biology 2008;320(2):319-27.
2008: Kathrin P Lampert; Dunja K Lamatsch; Petra Fischer; Manfred Schartl
A tetraploid Amazon molly, Poecilia formosa.
The Journal of heredity 2008;99(2):223-6.
2008: Indrajit Nanda; K Schlegelmilch; Thomas Haaf; Manfred Schartl; Michael Schmid
Synteny conservation of the Z chromosome in 14 avian species (11 families) supports a role for Z dosage in avian sex determination.
Cytogenetic and genome research 2008;122(2):150-6.
2007: Kathrin P Lampert; Dunja K Lamatsch; Petra Fischer; Jörg T Epplen; Indrajit Nanda; Michael Schmid; Manfred Schartl
Automictic reproduction in interspecific hybrids of poeciliid fish.
Current biology : CB 2007;17(22):1948-53.
2007: Yvonne Selz; Ingo Braasch; Carsten Hoffmann; Cornelia Schmidt; Christina Schultheis; Manfred Schartl; Jean-Nicolas Volff
Evolution of melanocortin receptors in teleost fish: the melanocortin type 1 receptor.
Gene 2007;401(1-2):114-22.
2007: Indrajit Nanda; Ingo Schlupp; Dunja K Lamatsch; Kathrin P Lampert; Michael Schmid; Manfred Schartl
Stable inheritance of host species-derived microchromosomes in the gynogenetic fish Poecilia formosa.
Genetics 2007;177(2):917-26.
2007: S M Maier; Stefan J Scherer; Markus Seifert; Rainer G Hanselmann; Y Schleehuber; L Edelmann; Jörg Reichrath; Georg Krohne; U Rescher; W Seidl; W Mutschler; L Claes; Cornelius Welter; Manfred Schartl
1[alpha],25-dihydroxyvitamin D(3) enhances annexin II dependent proliferation of osteoblasts.
Journal of cellular biochemistry 2007;100(3):679-92.
2007: Ute Hornung; Amaury Herpin; Manfred Schartl
Expression of the male determining gene dmrt1bY and its autosomal coorthologue dmrt1a in medaka.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2007;1(3):197-206.
2007: Jean-Nicolas Volff; Indrajit Nanda; Michael Schmid; Manfred Schartl
Governing sex determination in fish: regulatory putsches and ephemeral dictators.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2007;1(2):85-99.
2007: Kathrin P Lampert; Claus Steinlein; Michael Schmid; Petra Fischer; Manfred Schartl
A haploid-diploid-triploid mosaic of the Amazon molly, Poecilia formosa.
Cytogenetic and genome research 2007;119(1-2):131-4.
2007: Amaury Herpin; Detlev Schindler; Anita Kraiss; Ute Hornung; Christoph Winkler; Manfred Schartl
Inhibition of primordial germ cell proliferation by the medaka male determining gene Dmrt I bY.
BMC developmental biology 2007;7():99.
2007: Indrajit Nanda; E Karl; Darren K Griffin; Manfred Schartl; Michael Schmid
Chromosome repatterning in three representative parrots (Psittaciformes) inferred from comparative chromosome painting.
Cytogenetic and genome research 2007;117(1-4):43-53.
2007: Susanne Schories; Kathrin P Lampert; Dunja K Lamatsch; Francisco J García de León; Manfred Schartl
Analysis of a possible independent origin of triploid P. formosa outside of the Río Purificación river system.
Frontiers in zoology 2007;4():13.
2007: Ingo Braasch; Manfred Schartl; Jean-Nicolas Volff
Evolution of pigment synthesis pathways by gene and genome duplication in fish.
BMC evolutionary biology 2007;7():74.
2007: Amaury Herpin; Stefan Rohr; Dietmar Riedel; Nils Kluever; erez raz; Manfred Schartl
Specification of primordial germ cells in medaka (Oryzias latipes).
BMC developmental biology 2007;7():3.
2007: Nils Klüver; Frank Pfennig; Irene Pala; Katja Storch; Marlen Schlieder; Alexander Froschauer; Herwig O Gutzeit; Manfred Schartl
Differential expression of anti-Müllerian hormone (amh) and anti-Müllerian hormone receptor type II (amhrII) in the teleost medaka.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(1):271-81.
2007: Takashi Sasaki; Atsushi Shimizu; Sabine K Ishikawa; Shuichiro Imai; Shuichi Asakawa; Yuji Murayama; Maryam Zadeh Khorasani; Hiroshi Mitani; Makoto Furutani-Seiki; Hisato Kondoh; Indrajit Nanda; Michael Schmid; Manfred Schartl; Masaru Nonaka; Hiroyuki Takeda; Hiroshi Hori; Heinz Himmelbauer; Akihiro Shima; Nobuyoshi Shimizu
The DNA sequence of medaka chromosome LG22.
Genomics 2007;89(1):124-33.
2006: Jörg Renn; Christoph Winkler; Manfred Schartl; Rainer Fischer; Roland Goerlich
Zebrafish and medaka as models for bone research including implications regarding space-related issues.
Protoplasma 2006;229(2-4):209-14.
2006: Svenja Meierjohann; Manfred Schartl
From Mendelian to molecular genetics: the Xiphophorus melanoma model.
Trends in genetics : TIG 2006;22(12):654-61.
2006: Mariko Kondo; Ute Hornung; Indrajit Nanda; Shuichiro Imai; Takashi Sasaki; Atsushi Shimizu; Shuichi Asakawa; Hiroshi Hori; Michael Schmid; Nobuyoshi Shimizu; Manfred Schartl
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka.
Genome research 2006;16(7):815-26.
2006: Jörg Renn; Marianne Schaedel; Jean-Nicolas Volff; Roland Goerlich; Manfred Schartl; Christoph Winkler
Dynamic expression of sparc precedes formation of skeletal elements in the Medaka (Oryzias latipes).
Gene 2006;372():208-18.
2006: Kathrin P Lampert; Dunja K Lamatsch; Susanne Schories; Armin Hopf; Francisco J García de León; Manfred Schartl
Microsatellites for the gynogenetic Amazon molly, Poecilia formosa: useful tools for detection of mutation rate, ploidy determination and overall genetic diversity.
Journal of genetics 2006;85(1):67-71.
2006: Katrin Zunker; Jörg T Epplen; Manfred Schartl
Genomic stability in malignant melanoma of Xiphophorus.
Melanoma research 2006;16(2):105-13.
2006: Svenja Meierjohann; Elisabeth Wende; Anita Kraiss; Claudia Wellbrock; Manfred Schartl
The oncogenic epidermal growth factor receptor variant Xiphophorus melanoma receptor kinase induces motility in melanocytes by modulation of focal adhesions.
Cancer research 2006;66(6):3145-52.
2006: Nobuyoshi Shimizu; Takashi Sasaki; Shuichi Asakawa; Atsushi Shimizu; Sabine K Ishikawa; Shuichiro Imai; Yuji Murayama; Heinz Himmelbauer; Hiroshi Mitani; Makoto Furutani-Seiki; Hisato Kondoh; Manfred Schartl; Masaru Nonaka; Hiroyuki Takeda; Hiroshi Hori; Akihiro Shima
Comparative genomics of medaka and fugu.
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2006;1(1):6-12.
2006: Axel Meyer; Walter Salzburger; Manfred Schartl
Hybrid origin of a swordtail species (Teleostei: Xiphophorus clemenciae) driven by sexual selection.
Molecular ecology 2006;15(3):721-30.
2006: Frank Bollig; Rebecca Mehringer; Birgit Perner; Christina Hartung; Matthias Schäfer; Manfred Schartl; Jean-Nicolas Volff; Christoph Winkler; Christoph Englert
Identification and comparative expression analysis of a second wt1 gene in zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(2):554-61.
2006: Svenja Meierjohann; Thomas Mueller; Manfred Schartl; Manfred Buehner
A structural model of the extracellular domain of the oncogenic EGFR variant Xmrk.
Zebrafish 2006;3(3):359-69.
2006: Anne-Marie Veith; Matthias Schäfer; Nils Klüver; Cornelia Schmidt; Christina Schultheis; Manfred Schartl; Christoph Winkler; Jean-Nicolas Volff
Tissue-specific expression of dmrt genes in embryos and adults of the platyfish Xiphophorus maculatus.
Zebrafish 2006;3(3):325-37.
2006: Christina Schultheis; Qingchun Zhou; Alexander Froschauer; Indrajit Nanda; Yvonne Selz; Cornelia Schmidt; Sabine Matschl; Marina Wenning; Anne-Marie Veith; Mariam Naciri; Reinhold Hanel; Ingo Braasch; Agnes Dettai; Astrid Böhne; Catherine Ozouf-Costaz; Stefan Chilmonczyk; Béatrice Ségurens; Arnaud Couloux; Sylvie Bernard-Samain; Michael Schmid; Manfred Schartl; Jean-Nicolas Volff
Molecular analysis of the sex-determining region of the platyfish Xiphophorus maculatus.
Zebrafish 2006;3(3):299-309.
2006: Yunhan Hong; Manfred Schartl
Isolation and differentiation of medaka embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2006;329():3-16.
2006: Michael Schmid; CG Ziegler; Claus Steinlein; Indrajit Nanda; Manfred Schartl
Cytogenetics of the bleak (Alburnus alburnus), with special emphasis on the B chromosomes.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2006;14(3):231-42.
2006: Indrajit Nanda; E Karl; V Volobouev; Darren K Griffin; Manfred Schartl; Michael Schmid
Extensive gross genomic rearrangements between chicken and Old World vultures (Falconiformes: Accipitridae).
Cytogenetic and genome research 2006;112(3-4):286-95.
2005: Dirk Winnemoeller; Claudia Wellbrock; Manfred Schartl
Activating mutations in the extracellular domain of the melanoma inducing receptor Xmrk are tumorigenic in vivo.
International journal of cancer. Journal international du cancer 2005;117(5):723-9.
2005: Claudia Wellbrock; Christin Weisser; Jessica C Hassel; Petra Fischer; Jürgen Becker; Claudia S Vetter; Iris Behrmann; Marcin Kortylewski; Peter C Heinrich; Manfred Schartl
STAT5 contributes to interferon resistance of melanoma cells.
Current biology : CB 2005;15(18):1629-39.
2005: Matthias Stöck; Claus Steinlein; Dunja K Lamatsch; Manfred Schartl; Michael Schmid
Multiple origins of tetraploid taxa in the Eurasian Bufo viridis subgroup.
Genetica 2005;124(2-3):255-72.
2005: J Luo; Matthias Sanetra; Manfred Schartl; Axel Meyer
Strong reproductive skew among males in the multiply mated swordtail Xiphophorus multilineatus (Teleostei).
The Journal of heredity 2005;96(4):346-55.
2005: Manfred Schartl; Ute Hornung; Karen Hissmann; Jürgen Schauer; Hans Fricke
Genetics: relatedness among east African coelacanths.
Nature 2005;435(7044):901.
2005: Nils Klüver; Mariko Kondo; Amaury Herpin; Hiroshi Mitani; Manfred Schartl
Divergent expression patterns of Sox9 duplicates in teleosts indicate a lineage specific subfunctionalization.
Development genes and evolution 2005;215(6):297-305.
2005: Matthias Schäfer; Martina Rembold; Joachim Wittbrodt; Manfred Schartl; Christoph Winkler
Medial floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a.
Genes & development 2005;19(8):897-902.
2005: Kathrin P Lampert; Dunja K Lamatsch; Jörg T Epplen; Manfred Schartl
Evidence for a monophyletic origin of triploid clones of the Amazon molly, Poecilia formosa.
Evolution; international journal of organic evolution 2005;59(4):881-9.
2005: Matthias Schäfer; Doris Kinzel; Cordula Neuner; Manfred Schartl; Jean-Nicolas Volff; Christoph Winkler
Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk.
Mechanisms of development 2005;122(1):43-56.
2004: Manfred Schartl
Sex chromosome evolution in non-mammalian vertebrates.
Current opinion in genetics & development 2004;14(6):634-41.
2004: Mariko Kondo; Indrajit Nanda; Ute Hornung; Michael Schmid; Manfred Schartl
Evolutionary origin of the medaka Y chromosome.
Current biology : CB 2004;14(18):1664-9.
2004: Svenja Meierjohann; Manfred Schartl; Jean-Nicolas Volff
Genetic, biochemical and evolutionary facets of Xmrk-induced melanoma formation in the fish Xiphophorus.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;138(3):281-9.
2004: Christoph Winkler; Ute Hornung; Mariko Kondo; Cordula Neuner; Jutta Duschl; Akihiro Shima; Manfred Schartl
Developmentally regulated and non-sex-specific expression of autosomal dmrt genes in embryos of the Medaka fish (Oryzias latipes).
Mechanisms of development 2004;121(7-8):997-1005.
2004: Yunhan Hong; Christoph Winkler; Tongming Liu; Guixuan Chai; Manfred Schartl
Activation of the mouse Oct4 promoter in medaka embryonic stem cells and its use for ablation of spontaneous differentiation.
Mechanisms of development 2004;121(7-8):933-43.
2004: Manfred Schartl
A comparative view on sex determination in medaka.
Mechanisms of development 2004;121(7-8):639-45.
2004: Yunhan Hong; Songlin Chen; Jianfang Gui; Manfred Schartl
Retention of the developmental pluripotency in medaka embryonic stem cells after gene transfer and long-term drug selection for gene targeting in fish.
Transgenic research 2004;13(1):41-50.
2004: Ana Gómez; Jean-Nicolas Volff; Ute Hornung; Manfred Schartl; Claudia Wellbrock
Identification of a second egfr gene in Xiphophorus uncovers an expansion of the epidermal growth factor receptor family in fish.
Molecular biology and evolution 2004;21(2):266-75.
2004: Steven Kazianis; Rodney S Nairn; Ronald B Walter; Dennis A Johnston; Jay Kumar; David Trono; L Della Coletta; I Gimenez-Conti; J Douglas Rains; Earlanda Williams; Brian M Pino; Madonna M Mamerow; Kelli J Kochan; Manfred Schartl; Juergen Vielkind; Jean-Nicolas Volff; Bruce Woolcock; Donald C Morizot
The genetic map of Xiphophorus fishes represented by 24 multipoint linkage groups.
Zebrafish 2004;1(3):287-304.
2004: Manfred Schartl; Indrajit Nanda; Mariko Kondo; Michael Schmid; Shuichi Asakawa; Takashi Sasaki; Nobuyoshi Shimizu; Thorsten Henrich; Joachim Wittbrodt; Makoto Furutani-Seiki; Hisato Kondoh; Heinz Himmelbauer; Yunhan Hong; Akihiko Koga; Masaru Nonaka; Hiroshi Mitani; Akihiro Shima
Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI).
Methods in cell biology 2004;77():173-99.
2004: Dunja K Lamatsch; Indrajit Nanda; Ingo Schlupp; Jörg T Epplen; Michael Schmid; Manfred Schartl
Distribution and stability of supernumerary microchromosomes in natural populations of the Amazon molly, Poecilia formosa.
Cytogenetic and genome research 2004;106(2-4):189-94.
2003: Julia Béjar; Yunhan Hong; Manfred Schartl
Mitf expression is sufficient to direct differentiation of medaka blastula derived stem cells to melanocytes.
Development (Cambridge, England) 2003;130(26):6545-53.
2003: Jacqueline Delfgaauw; Jutta Duschl; Claudia Wellbrock; Christin Froschauer; Manfred Schartl; Joachim Altschmied
MITF-M plays an essential role in transcriptional activation and signal transduction in Xiphophorus melanoma.
Gene 2003;320():117-26.
2003: Anne-Marie Veith; Alexander Froschauer; Cornelia Körting; Indrajit Nanda; Reinhold Hanel; Michael Schmid; Manfred Schartl; Jean-Nicolas Volff
Cloning of the dmrt1 gene of Xiphophorus maculatus: dmY/dmrt1Y is not the master sex-determining gene in the platyfish.
Gene 2003;317(1-2):59-66.
2003: Jean-Nicolas Volff; Cornelia Körting; Alexander Froschauer; Qingchun Zhou; Brigitta Wilde; Christina Schultheis; Yvonne Selz; Kimberley Sweeney; Jutta Duschl; Katrin Wichert; Joachim Altschmied; Manfred Schartl
The Xmrk oncogene can escape nonfunctionalization in a highly unstable subtelomeric region of the genome of the fish Xiphophorus.
Genomics 2003;82(4):470-9.
2003: Stefan Scholz; Sabine Rösler; Michael Schäffer; Ute Hornung; Manfred Schartl; Herwig O Gutzeit
Hormonal induction and stability of monosex populations in the medaka (Oryzias latipes): expression of sex-specific marker genes.
Biology of reproduction 2003;69(2):673-8.
2003: Christoph Winkler; Matthias Schafer; Jutta Duschl; Manfred Schartl; Jean-Nicolas Volff
Functional divergence of two zebrafish midkine growth factors following fish-specific gene duplication.
Genome research 2003;13(6A):1067-81.
2003: Jean-Nicolas Volff; Mariko Kondo; Manfred Schartl
Medaka dmY/dmrt1Y is not the universal primary sex-determining gene in fish.
Trends in genetics : TIG 2003;19(4):196-9.
2003: Mariko Kondo; Indrajit Nanda; Ute Hornung; Shuichi Asakawa; Nobuyoshi Shimizu; Hiroshi Mitani; Michael Schmid; Akihiro Shima; Manfred Schartl
Absence of the candidate male sex-determining gene dmrt1b(Y) of medaka from other fish species.
Current biology : CB 2003;13(5):416-20.
2003: Akihiro Shima; Heinz Himmelbauer; Hiroshi Mitani; Makoto Furutani-Seiki; Joachim Wittbrodt; Manfred Schartl
Fish genomes flying. Symposium on Medaka Genomics.
EMBO reports 2003;4(2):121-5.
2003: Jean-Nicolas Volff; David Zarkower; Vivian J Bardwell; Manfred Schartl
Evolutionary dynamics of the DM domain gene family in metazoans.
Journal of molecular evolution 2003;57 Suppl 1():S241-9.
2003: Toni Wagner; Jörg Renn; T Riemensperger; Jean-Nicolas Volff; Reinhard W Köster; Roland Goerlich; Manfred Schartl; Christoph Winkler
The teleost fish medaka (Oryzias latipes) as genetic model to study gravity dependent bone homeostasis in vivo.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) 2003;32(8):1459-65.
2003: Jean-Nicolas Volff; Manfred Schartl
Evolution of signal transduction by gene and genome duplication in fish.
Journal of structural and functional genomics 2003;3(1-4):139-50.
2003: CG Ziegler; Dunja K Lamatsch; Claus Steinlein; W Engel; Manfred Schartl; Michael Schmid
The giant B chromosome of the cyprinid fish Alburnus alburnus harbours a retrotransposon-derived repetitive DNA sequence.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2003;11(1):23-35.
2003: Indrajit Nanda; Ute Hornung; Mariko Kondo; Michael Schmid; Manfred Schartl
Common spontaneous sex-reversed XX males of the medaka Oryzias latipes.
Genetics 2003;163(1):245-51.
2002: Indrajit Nanda; David Schrama; Wolfgang Feichtinger; Thomas Haaf; Manfred Schartl; Michael Schmid
Distribution of telomeric (TTAGGG)(n) sequences in avian chromosomes.
Chromosoma 2002;111(4):215-27.
2002: Claudia Wellbrock; Ana Gómez; Manfred Schartl
Melanoma development and pigment cell transformation in xiphophorus.
Microscopy research and technique 2002;58(6):456-63.
2002: Indrajit Nanda; Mariko Kondo; Ute Hornung; Shuichi Asakawa; Christoph Winkler; Atsushi Shimizu; Zhihong Shan; Thomas Haaf; Nobuyoshi Shimizu; Akihiro Shima; Michael Schmid; Manfred Schartl
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11778-83.
2002: Enchshargal Zend-Ajusch; Ute Hornung; Carola Burgtorf; Götz Lütjens; Zhihong Shan; Manfred Schartl; Thomas Haaf
Isolation and characterization of cold-shock domain protein genes, Oryzias latipes Y-box protein 2 (OlaYP2) and Fugu rubripes Y-box protein 1 (FruYP1), in medakafish and pufferfish.
Gene 2002;296(1-2):111-9.
2002: Eva Geissinger; Christin Weisser; Petra Fischer; Manfred Schartl; Claudia Wellbrock
Autocrine stimulation by osteopontin contributes to antiapoptotic signalling of melanocytes in dermal collagen.
Cancer research 2002;62(16):4820-8.
2002: Alexander Froschauer; Cornelia Körting; Takayuki Katagiri; Takashi Aoki; Shuichi Asakawa; Nobuyoshi Shimizu; Manfred Schartl; Jean-Nicolas Volff
Construction and initial analysis of bacterial artificial chromosome (BAC) contigs from the sex-determining region of the platyfish Xiphophorus maculatus.
Gene 2002;295(2):247-54.
2002: Mariko Kondo; Alexander Froschauer; Akiko Kitano; Indrajit Nanda; Ute Hornung; Jean-Nicolas Volff; Shuichi Asakawa; Hiroshi Mitani; Kiyoshi Naruse; Minoru Tanaka; Michael Schmid; Nobuyoshi Shimizu; Manfred Schartl; Akihiro Shima
Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculatus.
Gene 2002;295(2):213-22.
2002: Joachim Altschmied; Jacqueline Delfgaauw; Brigitta Wilde; Jutta Duschl; Laurence Bouneau; Jean-Nicolas Volff; Manfred Schartl
Subfunctionalization of duplicate mitf genes associated with differential degeneration of alternative exons in fish.
Genetics 2002;161(1):259-67.
2002: Jessica C Morcinek; Christin Weisser; Eva Geissinger; Manfred Schartl; Claudia Wellbrock
Activation of STAT5 triggers proliferation and contributes to anti-apoptotic signalling mediated by the oncogenic Xmrk kinase.
Oncogene 2002;21(11):1668-78.
2002: Matthias Stöck; Dunja K Lamatsch; Claus Steinlein; Jörg T Epplen; Wolf-Rüdiger Grosse; Robert Hock; Thomas Klapperstück; Kathrin P Lampert; Ulrich Scheer; Michael Schmid; Manfred Schartl
A bisexually reproducing all-triploid vertebrate.
Nature genetics 2002;30(3):325-8.
2002: Claudia Wellbrock; Christin Weisser; Eva Geissinger; Jakob Troppmair; Manfred Schartl
Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling.
The Journal of biological chemistry 2002;277(8):6443-54.
2002: Nina K Lauer; Sandra M Maier; Martin Oberringer; Michael Schulte; Wolf Mutschler; Rainer G Hanselmann; Manfred Schartl; Stefan J Scherer; Reiner J Wirbel
Absence of telomerase activity in malignant bone tumors and soft-tissue sarcomas.
Sarcoma 2002;6(1):43-6.
2002: Michael Schmid; Wolfgang Feichtinger; Claus Steinlein; Thomas Haaf; Manfred Schartl; R Visbal García; J Manzanilla Pupo; A Fernández Badillo
Chromosome banding in Amphibia. XXVI. Coexistence of homomorphic XY sex chromosomes and a derived Y-autosome translocation in Eleutherodactylus maussi (Anura, Leptodactylidae).
Cytogenetic and genome research 2002;99(1-4):330-43.
2002: Jean-Nicolas Volff; Manfred Schartl
Sex determination and sex chromosome evolution in the medaka, Oryzias latipes, and the platyfish, Xiphophorus maculatus.
Cytogenetic and genome research 2002;99(1-4):170-7.
2002: Joachim Wittbrodt; Akihiro Shima; Manfred Schartl
Medaka--a model organism from the far East.
Nature reviews. Genetics 2002;3(1):53-64.
2001: B Brunner; Ute Hornung; Zhihong Shan; Indrajit Nanda; Mariko Kondo; Enchshargal Zend-Ajusch; Thomas Haaf; Hans-Hilger Ropers; Akihiro Shima; Michael Schmid; Vera Kalscheuer; Manfred Schartl
Genomic organization and expression of the doublesex-related gene cluster in vertebrates and detection of putative regulatory regions for DMRT1.
Genomics 2001;77(1-2):8-17.
2001: Alexander Froschauer; Cornelia Körting; W Bernhardt; Indrajit Nanda; Michael Schmid; Manfred Schartl; Jean-Nicolas Volff
Genomic plasticity and melanoma formation in the fish Xiphophorus.
Marine biotechnology (New York, N.Y.) 2001;3(Supplement 1):S72-80.
2001: Jean-Nicolas Volff; Ute Hornung; Manfred Schartl
Fish retroposons related to the Penelope element of Drosophila virilis define a new group of retrotransposable elements.
Molecular genetics and genomics : MGG 2001;265(4):711-20.
2001: Jean-Nicolas Volff; Cornelia Körting; Alexander Froschauer; Kimberley Sweeney; Manfred Schartl
Non-LTR retrotransposons encoding a restriction enzyme-like endonuclease in vertebrates.
Journal of molecular evolution 2001;52(4):351-60.
2001: Jean-Nicolas Volff; Cornelia Körting; A Meyer; Manfred Schartl
Evolution and discontinuous distribution of Rex3 retrotransposons in fish.
Molecular biology and evolution 2001;18(3):427-31.
2001: S Chen; Yunhan Hong; Stefan J Scherer; Manfred Schartl
Lack of ultraviolet-light inducibility of the medakafish (Oryzias latipes) tumor suppressor gene p53.
Gene 2001;264(2):197-203.
2001: Ana Gómez; Claudia Wellbrock; H Gutbrod; N Dimitrijevic; Manfred Schartl
Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain.
The Journal of biological chemistry 2001;276(5):3333-40.
2001: Jean-Nicolas Volff; Cornelia Körting; Joachim Altschmied; Jutta Duschl; Kimberley Sweeney; Katrin Wichert; Alexander Froschauer; Manfred Schartl
Jule from the fish Xiphophorus is the first complete vertebrate Ty3/Gypsy retrotransposon from the Mag family.
Molecular biology and evolution 2001;18(2):101-11.
2001: Jean-Nicolas Volff; Manfred Schartl
Variability of genetic sex determination in poeciliid fishes.
Genetica 2001;111(1-3):101-10.
2000: Stefan J Scherer; S M Maier; Markus Seifert; Rainer G Hanselmann; KD Zang; H K Muller-Hermelink; P Angel; Cornelius Welter; Manfred Schartl
p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV.
The Journal of biological chemistry 2000;275(48):37469-73.
2000: Jean-Nicolas Volff; Cornelia Körting; Manfred Schartl
Multiple lineages of the non-LTR retrotransposon Rex1 with varying success in invading fish genomes.
Molecular biology and evolution 2000;17(11):1673-84.
2000: Indrajit Nanda; Jean-Nicolas Volff; S Weis; Cornelia Körting; Alexander Froschauer; Michael Schmid; Manfred Schartl
Amplification of a long terminal repeat-like element on the Y chromosome of the platyfish, Xiphophorus maculatus.
Chromosoma 2000;109(3):173-80.
2000: Claudia Wellbrock; Manfred Schartl
Activation of phosphatidylinositol 3-kinase by a complex of p59fyn and the receptor tyrosine kinase Xmrk is involved in malignant transformation of pigment cells.
European journal of biochemistry / FEBS 2000;267(12):3513-22.
2000: Joachim Altschmied; Jean-Nicolas Volff; Christoph Winkler; H Gutbrod; Cornelia Körting; M Pagany; Manfred Schartl
Primary structure and expression of the xiphophorus DNA-(cytosine-5)-methyltransferase XDNMT-1.
Gene 2000;249(1-2):75-82.
2000: Dunja K Lamatsch; Claus Steinlein; Michael Schmid; Manfred Schartl
Noninvasive determination of genome size and ploidy level in fishes by flow cytometry: detection of triploid Poecilia formosa.
Cytometry 2000;39(2):91-5.
2000: Dunja K Lamatsch; Indrajit Nanda; Jörg T Epplen; Michael Schmid; Manfred Schartl
Unusual triploid males in a microchromosome-carrying clone of the Amazon molly, Poecilia formosa.
Cytogenetics and cell genetics 2000;91(1-4):148-56.
2000: Indrajit Nanda; Enchshargal Zend-Ajusch; Zhihong Shan; Frank Grützner; Manfred Schartl; David W Burt; MR Koehler; V M Fowler; G Goodwin; W J Schneider; S Mizuno; G Dechant; Thomas Haaf; Michael Schmid
Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination.
Cytogenetics and cell genetics 2000;89(1-2):67-78.
1999: Axel Meyer; Manfred Schartl
Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions.
Current opinion in cell biology 1999;11(6):699-704.
1999: Jean-Nicolas Volff; Cornelia Körting; Kimberley Sweeney; Manfred Schartl
The non-LTR retrotransposon Rex3 from the fish Xiphophorus is widespread among teleosts.
Molecular biology and evolution 1999;16(11):1427-38.
1999: Manfred Schartl; Ute Hornung; H Gutbrod; Jean-Nicolas Volff; Joachim Wittbrodt
Melanoma loss-of-function mutants in Xiphophorus caused by Xmrk-oncogene deletion and gene disruption by a transposable element.
Genetics 1999;153(3):1385-94.
1999: Claudia Wellbrock; Petra Fischer; Manfred Schartl
PI3-kinase is involved in mitogenic signaling by the oncogenic receptor tyrosine kinase Xiphophorus melanoma receptor kinase in fish melanoma.
Experimental cell research 1999;251(2):340-9.
1999: M Baudler; Manfred Schartl; Joachim Altschmied
Specific activation of a STAT family member in Xiphophorus melanoma cells.
Experimental cell research 1999;249(2):212-20.
1999: Indrajit Nanda; Zhihong Shan; Manfred Schartl; David W Burt; MR Koehler; H Nothwang; Frank Grützner; Ian R Paton; D Windsor; I Dunn; Wolfgang Engel; P Staeheli; S Mizuno; Thomas Haaf; Michael Schmid
300 million years of conserved synteny between chicken Z and human chromosome 9.
Nature genetics 1999;21(3):258-9.
1999: Claudia Wellbrock; Manfred Schartl
Multiple binding sites in the growth factor receptor Xmrk mediate binding to p59fyn, GRB2 and Shc.
European journal of biochemistry / FEBS 1999;260(1):275-83.
1999: H Gutbrod; Manfred Schartl
Intragenic sex-chromosomal crossovers of Xmrk oncogene alleles affect pigment pattern formation and the severity of melanoma in Xiphophorus.
Genetics 1999;151(2):773-83.
1998: Manfred Schartl; Brigitta Wilde; Ute Hornung
Triplet repeat variability in the signal peptide sequence of the Xmrk receptor tyrosine kinase gene in Xiphophorus fish.
Gene 1998;224(1-2):17-21.
1998: Yunhan Hong; Christoph Winkler; Manfred Schartl
Efficiency of cell culture derivation from blastula embryos and of chimera formation in the medaka (Oryzias latipes) depends on donor genotype and passage number.
Development genes and evolution 1998;208(10):595-602.
1998: S Weis; Manfred Schartl
The macromelanophore locus and the melanoma oncogene Xmrk are separate genetic entities in the genome of Xiphophorus.
Genetics 1998;149(4):1909-20.
1998: Claudia Wellbrock; Eva Geissinger; Ana Gómez; Petra Fischer; Karlheinz Friedrich; Manfred Schartl
Signalling by the oncogenic receptor tyrosine kinase Xmrk leads to activation of STAT5 in Xiphophorus melanoma.
Oncogene 1998;16(23):3047-56.
1998: Indrajit Nanda; C Sick; Uwe Münster; Bernd Kaspers; Manfred Schartl; Peter Staeheli; Michael Schmid
Sex chromosome linkage of chicken and duck type I interferon genes: further evidence of evolutionary conservation of the Z chromosome in birds.
Chromosoma 1998;107(3):204-10.
1998: Claudia Wellbrock; Petra Fischer; Manfred Schartl
Receptor tyrosine kinase Xmrk mediates proliferation in Xiphophorus melanoma cells.
International journal of cancer. Journal international du cancer 1998;76(3):437-42.
1998: N Dimitrijevic; Christoph Winkler; Claudia Wellbrock; Ana Gómez; Jutta Duschl; Joachim Altschmied; Manfred Schartl
Activation of the Xmrk proto-oncogene of Xiphophorus by overexpression and mutational alterations.
Oncogene 1998;16(13):1681-90.
1998: Yunhan Hong; Christoph Winkler; Manfred Schartl
Production of medakafish chimeras from a stable embryonic stem cell line.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3679-84.
1998: Ingo Schlupp; Indrajit Nanda; M Döbler; Dunja K Lamatsch; Jörg T Epplen; J Parzefall; Michael Schmid; Manfred Schartl
Dispensable and indispensable genes in an ameiotic fish, the Amazon molly Poecilia formosa.
Cytogenetics and cell genetics 1998;80(1-4):193-8.
1997: Joachim Altschmied; L Ditzel; Manfred Schartl
Hypomethylation of the Xmrk oncogene promoter in melanoma cells of Xiphophorus.
Biological chemistry 1997;378(12):1457-66.
1997: MR Koehler; Thomas Haaf; M Guttenbach; Manfred Schartl; Michael Schmid
Cytogenetics of the genus Leporinus (Pisces, Anostomidae). II. Molecular cytogenetics, organization and evolutionary conservation of a chromosome-specific satellite DNA from Leporinus obtusidens.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1997;5(5):325-31.
1997: Joachim Altschmied; Ute Hornung; Ingo Schlupp; Jürgen Gadau; R Kolb; Manfred Schartl
Isolation of DNA suitable for PCR for field and laboratory work.
BioTechniques 1997;23(2):228-9.
1997: A Schartl; Ute Hornung; Indrajit Nanda; R Wacker; H K Müller-Hermelink; Ingo Schlupp; J Parzefall; Michael Schmid; Manfred Schartl
Susceptibility to the development of pigment cell tumors in a clone of the Amazon molly, Poecilia formosa, introduced through a microchromosome.
Cancer research 1997;57(14):2993-3000.
1997: Claudia Wellbrock; Ana Gómez; Manfred Schartl
Signal transduction by the oncogenic receptor tyrosine kinase Xmrk in melanoma formation of Xiphophorus.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1997;10(1-2):34-40.
1997: M Baudler; Jutta Duschl; Christoph Winkler; Manfred Schartl; Joachim Altschmied
Activation of transcription of the melanoma inducing Xmrk oncogene by a GC box element.
The Journal of biological chemistry 1997;272(1):131-7.
1997: A Schartl; M Pagany; M Engler; Manfred Schartl
Analysis of genetic factors and molecular mechanisms in the development of hereditary and carcinogen-induced tumors of Xiphophorus.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1997;143():225-35.
1996: Y Hong; Christoph Winkler; Manfred Schartl
Pluripotency and differentiation of embryonic stem cell lines from the medakafish (Oryzias latipes).
Mechanisms of development 1996;60(1):33-44.
1996: Indrajit Nanda; S Weis; D Förnzler; Joachim Altschmied; Manfred Schartl; Michael Schmid
Clustered organization and conservation of the Xiphophorus maculatus D locus, which includes two distinct gene sequences.
Chromosoma 1996;105(4):242-9.
1996: A Schartl; Manfred Schartl
Tumor induction and tumor regression in Xiphophorus.
In vivo (Athens, Greece) 1996;10(2):179-84.
1996: D Förnzler; Joachim Altschmied; Indrajit Nanda; R Kolb; M Baudler; Michael Schmid; Manfred Schartl
The Xmrk oncogene promoter is derived from a novel amplified locus of unusual organization.
Genome research 1996;6(2):102-13.
1995: B Malitschek; D Förnzler; Manfred Schartl
Melanoma formation in Xiphophorus: a model system for the role of receptor tyrosine kinases in tumorigenesis.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(12):1017-23.
1995: Claudia Wellbrock; Reiner Lammers; A Ullrich; Manfred Schartl
Association between the melanoma-inducing receptor tyrosine kinase Xmrk and src family tyrosine kinases in Xiphophorus.
Oncogene 1995;10(11):2135-43.
1995: Manfred Schartl
Platyfish and swordtails: a genetic system for the analysis of molecular mechanisms in tumor formation.
Trends in genetics : TIG 1995;11(5):185-9.
1995: A Schartl; B Malitschek; Steven Kazianis; R Borowsky; Manfred Schartl
Spontaneous melanoma formation in nonhybrid Xiphophorus.
Cancer research 1995;55(1):159-65.
1994: A Schartl; N Dimitrijevic; Manfred Schartl
Evolutionary origin and molecular biology of the melanoma-inducing oncogene of Xiphophorus.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1994;7(6):428-32.
1994: R Götz; Reinhard W Köster; C Winkler; F Raulf; F Lottspeich; Manfred Schartl; H Thoenen
Neurotrophin-6 is a new member of the nerve growth factor family.
Nature 1994;372(6503):266-9.
1994: Christoph Winkler; J Wittbrodt; Reiner Lammers; A Ullrich; Manfred Schartl
Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene.
Oncogene 1994;9(6):1517-25.
1994: B Malitschek; J Wittbrodt; Petra Fischer; Reiner Lammers; A Ullrich; Manfred Schartl
Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand.
The Journal of biological chemistry 1994;269(14):10423-30.
1993: W Mäueler; A Schartl; Manfred Schartl
Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of Xiphophorus.
International journal of cancer. Journal international du cancer 1993;55(2):288-96.
1993: Manfred Schartl; C Erbelding-Denk; S Hölter; Indrajit Nanda; M Schmid; J H Schröder; J T Epplen
Reproductive failure of dominant males in the poeciliid fish Limia perugiae determined by DNA fingerprinting.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7064-8.
1993: Indrajit Nanda; Manfred Schartl; J T Epplen; W Feichtinger; Michael Schmid
Primitive sex chromosomes in poeciliid fishes harbor simple repetitive DNA sequences.
The Journal of experimental zoology 1993;265(3):301-8.
1993: D Adam; N Dimitrijevic; Manfred Schartl
Tumor suppression in Xiphophorus by an accidentally acquired promoter.
Science (New York, N.Y.) 1993;259(5096):816-9.
1992: J Wittbrodt; Reiner Lammers; B Malitschek; A Ullrich; Manfred Schartl
The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma.
The EMBO journal 1992;11(11):4239-46.
1992: Y Hong; Manfred Schartl
Structure of the rainbow trout metallothionein A gene.
Gene 1992;120(2):277-9.
1992: R Götz; F Raulf; Manfred Schartl
Brain-derived neurotrophic factor is more highly conserved in structure and function than nerve growth factor during vertebrate evolution.
Journal of neurochemistry 1992;59(2):432-42.
1992: S Ottilie; F Raulf; A Barnekow; G Hannig; Manfred Schartl
Multiple src-related kinase genes, srk1-4, in the fresh water sponge Spongilla lacustris.
Oncogene 1992;7(8):1625-30.
1992: Christoph Winkler; Y Hong; J Wittbrodt; Manfred Schartl
Analysis of heterologous and homologous promoters and enhancers in vitro and in vivo by gene transfer into Japanese medaka (Oryzias latipes) Xiphophorus.
Molecular marine biology and biotechnology 1992;1(4-5):326-37.
1992: Indrajit Nanda; Manfred Schartl; W Feichtinger; J T Epplen; Michael Schmid
Early stages of sex chromosome differentiation in fish as analysed by simple repetitive DNA sequences.
Chromosoma 1992;101(5-6):301-10.
1992: Manfred Schartl; D Adam
Molecular cloning, structural characterization, and analysis of transcription of the melanoma oncogene of xiphophorus.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1992;Suppl 2():173-80.
1991: D Förnzler; J Wittbrodt; Manfred Schartl
Analysis of an esterase linked to a locus involved in the regulation of the melanoma oncogene and isolation of polymorphic marker sequences in Xiphophorus.
Biochemical genetics 1991;29(11-12):509-24.
1991: Manfred Schartl; Ingo Schlupp; A Schartl; M K Meyer; Indrajit Nanda; M Schmid; J T Epplen; J Parzefall
On the stability of dispensable constituents of the eukaryotic genome: stability of coding sequences versus truly hypervariable sequences in a clonal vertebrate, the amazon molly, Poecilia formosa.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8759-63.
1991: B Malitschek; Manfred Schartl
Rapid identification of recombinant baculoviruses using PCR.
BioTechniques 1991;11(2):177-8.
1991: Christoph Winkler; J R Vielkind; Manfred Schartl
Transient expression of foreign DNA during embryonic and larval development of the medaka fish (Oryzias latipes).
Molecular & general genetics : MGG 1991;226(1-2):129-40.
1991: G Hannig; S Ottilie; Manfred Schartl
Conservation of structure and expression of the c-yes and fyn genes in lower vertebrates.
Oncogene 1991;6(3):361-9.
1991: D Adam; W Mäueler; Manfred Schartl
Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus.
Oncogene 1991;6(1):73-80.
1990: Manfred Schartl
Homology of melanoma-inducing loci in the genus Xiphophorus.
Genetics 1990;126(4):1083-91.
1990: H Friedenreich; Manfred Schartl
Transient expression directed by homologous and heterologous promoter and enhancer sequences in fish cells.
Nucleic acids research 1990;18(11):3299-305.
1989: J Wittbrodt; D Adam; B Malitschek; W Mäueler; F Raulf; A Telling; S M Robertson; Manfred Schartl
Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus.
Nature 1989;341(6241):415-21.
1989: Manfred Schartl; T Holstein; S M Robertson; A Barnekow
Preferential expression of a pp60c-src related protein tyrosine kinase activity in nerve cells of the early metazoan Hydra (Coelenterates).
Oncogene 1989;4(10):1185-91.
1989: F Raulf; S M Robertson; Manfred Schartl
Evolution of the neuron-specific alternative splicing product of the c-src proto-oncogene.
Journal of neuroscience research 1989;24(1):81-8.
1989: F Raulf; W Mäueler; S M Robertson; Manfred Schartl
Localization of cellular src mRNA during development and in the differentiated bipolar neurons of the adult neural retina in Xiphophorus.
Oncogene research 1989;5(1):39-47.
1988: D Adam; J Wittbrodt; A Telling; Manfred Schartl
RFLP for an EGF-receptor related gene associated with the melanoma oncogene locus of Xiphophorus maculatus.
Nucleic acids research 1988;16(14B):7212.
1988: Manfred Schartl
A sex chromosomal restriction-fragment-length marker linked to melanoma-determining Tu loci in Xiphophorus.
Genetics 1988;119(3):679-85.
1988: W Mäueler; F Raulf; Manfred Schartl
Expression of proto-oncogenes in embryonic, adult, and transformed tissue of Xiphophorus (Teleostei: Poeciliidae).
Oncogene 1988;2(5):421-30.
1988: Manfred Schartl; R U Peter
Progressive growth of fish tumors after transplantation into thymus-aplastic (nu/nu) mice.
Cancer research 1988;48(3):741-4.
1988: Manfred Schartl; W Mäueler; F Raulf; S M Robertson
Molecular aspects of melanoma formation in Xiphophorus.
Progress in clinical and biological research 1988;256():283-96.