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Alan Schechter

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Vladan P Čokić; Reginald D Smith; Angélique Biancotto; Constance T Noguchi; Raj K Puri; Alan N Schechter
Globin gene expression in correlation with G protein-related genes during erythroid differentiation.
Ji Won Park; Barbora Piknova; Paul L Huang; Constance T Noguchi; Alan N Schechter
Effect of blood nitrite and nitrate levels on murine platelet function.
Ji Won Park; Barbora Piknova; Alan N Schechter
In reply.

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All Publications

2013: Vladan P Čokić; Reginald D Smith; Angélique Biancotto; Constance T Noguchi; Raj K Puri; Alan N Schechter
Globin gene expression in correlation with G protein-related genes during erythroid differentiation.
BMC genomics 2013;14():116.
2013: Ji Won Park; Barbora Piknova; Paul L Huang; Constance T Noguchi; Alan N Schechter
Effect of blood nitrite and nitrate levels on murine platelet function.
PloS one 2013;8(2):e55699.
2013: Ji Won Park; Barbora Piknova; Alan N Schechter
In reply.
Transfusion 2013;53(1):235.
2012: Ajay Machha; Alan N Schechter
Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables?
Nutrition reviews 2012;70(6):367-72.
2012: Vladan P Cokic; Constance T Noguchi; Raj K Puri; Bojana B Beleslin-Cokic; Bhaskar Bhattacharya; Alan N Schechter
JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny.
Journal of translational medicine 2012;10():116.
2012: Sirada Srihirun; Thanaporn Sriwantana; Supeenun Unchern; Suthat Fucharoen; Dusadee Kittikool; Egarit Noulsri; Kovit Pattanapanyasat; Barbora Piknova; Alan N Schechter; Nathawut Sibmooh
Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation.
PloS one 2012;7(1):e30380.
2011: Ajay Machha; Alan N Schechter
Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits.
European journal of nutrition 2011;50(5):293-303.
2011: Ruifeng Teng; John W Calvert; Nathawut Sibmooh; Barbora Piknova; Norio Suzuki; Junhui Sun; Kevin Martinez; Masayuki Yamamoto; Alan N Schechter; David J Lefer; Constance Tom Noguchi
Acute erythropoietin cardioprotection is mediated by endothelial response.
Basic research in cardiology 2011;106(3):343-54.
2011: Bojana B Beleslin-Čokić; Vladan P Cokić; Li Wang; Barbora Piknova; Ruifeng Teng; Alan N Schechter; Constance T Noguchi
Erythropoietin and hypoxia increase erythropoietin receptor and nitric oxide levels in lung microvascular endothelial cells.
Cytokine 2011;54(2):129-35.
2011: Barbora Piknova; Alan N Schechter
Measurement of nitrite in blood samples using the ferricyanide-based hemoglobin oxidation assay.
Methods in molecular biology (Clifton, N.J.) 2011;704():39-56.
2009: Vladan P Cokić; Bojana B Beleslin-Cokić; Reginald D Smith; Antaeus P Economou; Larry M Wahl; Constance Tom Noguchi; Alan N Schechter
Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production.
Experimental hematology 2009;37(10):1230-7.
2009: Barbora Piknova; Agnes Keszler; Neil Hogg; Alan N Schechter
The reaction of cell-free oxyhemoglobin with nitrite under physiologically relevant conditions: Implications for nitrite-based therapies.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2009;20(2):88-94.
2008: Alan N Schechter
Hemoglobin research and the origins of molecular medicine.
Blood 2008;112(10):3927-38.
2008: Agnes Keszler; Barbora Piknova; Alan N Schechter; Neil Hogg
The reaction between nitrite and oxyhemoglobin: a mechanistic study.
The Journal of biological chemistry 2008;283(15):9615-22.
2008: Nathawut Sibmooh; Barbora Piknova; Fabiola Rizzatti; Alan N Schechter
Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes.
Biochemistry 2008;47(9):2989-96.
2008: Vladan P Cokic; Silvana A Andric; Stanko S Stojilkovic; Constance Tom Noguchi; Alan N Schechter
Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells.
Blood 2008;111(3):1117-23.
2008: Vladan P Cokić; Alan N Schechter
Effects of nitric oxide on red blood cell development and phenotype.
Current topics in developmental biology 2008;82():169-215.
2007: André Dejam; Christian Hunter; Carole Tremonti; Ryszard M Pluta; Yuen Yi Hon; George Grimes; Kristine S Partovi; Mildred M Pelletier; Edward H Oldfield; Richard O Cannon; Alan N Schechter; Mark T Gladwin
Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation.
Circulation 2007;116(16):1821-31.
2007: Katherine J Deans; Peter C Minneci; Anthony F Suffredini; Robert L Danner; William D Hoffman; Xizhong Ciu; HARVEY KLEIN; Alan N Schechter; Steven M Banks; Peter Q Eichacker; Charles Natanson
Randomization in clinical trials of titrated therapies: unintended consequences of using fixed treatment protocols.
Critical care medicine 2007;35(6):1509-16.
2007: Vladan P Cokic; Bojana B Beleslin-Cokic; Constance Tom Noguchi; Alan N Schechter
Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;16(3):371-8.
2007: Lewis Hsu; Hunter C Champion; Sally A Campbell-Lee; Trinity J Bivalacqua; Elizabeth A Manci; Bhalchandra A Diwan; Daniel M Schimel; Audrey E Cochard; Xunde Wang; Alan N Schechter; Constance T Noguchi; Mark T Gladwin
Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.
Blood 2007;109(7):3088-98.
2006: Patricia A Oneal; Nicole M Gantt; Joseph D Schwartz; Natarajan V Bhanu; Y Terry Lee; John W Moroney; Christopher H Reed; Alan N Schechter; Naomi L C Luban; Jeffery L Miller
Fetal hemoglobin silencing in humans.
Blood 2006;108(6):2081-6.
2006: Mildred M Pelletier; Petra Kleinbongard; Lorna A Ringwood; Rania Hito; Christian Hunter; Alan N Schechter; Mark T Gladwin; André Dejam
The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions.
Free radical biology & medicine 2006;41(4):541-8.
2006: Mikaela K Holly; James W Dear; Xuzhen Hu; Alan N Schechter; Mark T Gladwin; Stephen M Hewitt; Peter S T Yuen; robert star
Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure.
Kidney international 2006;70(3):496-506.
2006: Vladan P Cokic; Bojana B Beleslin-Cokic; Melanija Tomic; Stanko S Stojilkovic; Constance Tom Noguchi; Alan N Schechter
Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells.
Blood 2006;108(1):184-91.
2006: Daniel B Kim-Shapiro; Alan N Schechter; Mark T Gladwin
Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):697-705.
2006: Petra Kleinbongard; André Dejam; Thomas Lauer; Thomas Jax; Stefan Kerber; Putrika Gharini; Jan Balzer; Rainer B Zotz; Rüdiger E Scharf; Reinhart Willers; Alan N Schechter; Martin Feelisch; Malte Kelm
Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans.
Free radical biology & medicine 2006;40(2):295-302.
2006: Jack H Crawford; T Scott Isbell; Zhi Huang; Sruti Shiva; Balu K Chacko; Alan N Schechter; Victor Darley-Usmar; Jeffrey D Kerby; John D Lang; David Kraus; Chien Ho; Mark T Gladwin; Rakesh P Patel
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation.
Blood 2006;107(2):566-74.
2005: Peter C Minneci; Katherine J Deans; Huang Zhi; Peter S T Yuen; robert star; Steven M Banks; Alan N Schechter; Charles Natanson; Mark T Gladwin; Steven B Solomon
Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin.
The Journal of clinical investigation 2005;115(12):3409-17.
2005: Mark T Gladwin; Alan N Schechter; Daniel B Kim-Shapiro; Rakesh P Patel; Neil Hogg; Sruti Shiva; Richard O Cannon; Malte Kelm; David A Wink; Michael G Espey; Edward H Oldfield; Ryszard M Pluta; Bruce Freeman; Jack R Lancaster; Martin Feelisch; Jon O Lundberg
The emerging biology of the nitrite anion.
Nature chemical biology 2005;1(6):308-14.
2005: Zhi Huang; Sruti Shiva; Daniel B Kim-Shapiro; Rakesh P Patel; Lorna A Ringwood; Cynthia E Irby; Kris T Huang; Chien Ho; Neil Hogg; Alan N Schechter; Mark T Gladwin
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control.
The Journal of clinical investigation 2005;115(8):2099-107.
2005: André Dejam; Christian Hunter; Mildred M Pelletier; Lewis Hsu; Roberto Machado; Sruti Shiva; Gordon G Power; Malte Kelm; Mark T Gladwin; Alan N Schechter
Erythrocytes are the major intravascular storage sites of nitrite in human blood.
Blood 2005;106(2):734-9.
2004: Christian Hunter; André Dejam; Arlin Blood; Howard Shields; Daniel B Kim-Shapiro; Roberto Machado; Selamawit Tarekegn; Neda Mulla; Andrew O Hopper; Alan N Schechter; Gordon G Power; Mark T Gladwin
Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator.
Nature medicine 2004;10(10):1122-7.
2004: Bojana B Beleslin-Cokic; Vladan P Cokic; Xiaobing Yu; Babette B Weksler; Alan N Schechter; Constance Tom Noguchi
Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.
Blood 2004;104(7):2073-80.
2004: David F Stroncek; Karen M Byrne; Constance Tom Noguchi; Alan N Schechter; Susan F Leitman
Increasing hemoglobin oxygen saturation levels in sickle trait donor whole blood prevents hemoglobin S polymerization and allows effective white blood cell reduction by filtration.
Transfusion 2004;44(9):1293-9.
2004: Hiroshi Taniuchi; Alan N Schechter; Joseph Shiloach
Linderstrom-Lang-Schellman's model for protein stabilization revisited.
Current protein & peptide science 2004;5(4):275-86.
2004: André Dejam; Christian Hunter; Alan N Schechter; Mark T Gladwin
Emerging role of nitrite in human biology.
Blood cells, molecules & diseases 2004;32(3):423-9.
2004: Mark T Gladwin; Vandana Sachdev; Maria L Jison; Yukitaka Shizukuda; Jonathan F Plehn; Karin Minter; Bernice Brown; Wynona A Coles; James S Nichols; Inez Ernst; Lori A Hunter; William C Blackwelder; Alan N Schechter; Griffin P Rodgers; Oswaldo Castro; Frederick P Ognibene
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
The New England journal of medicine 2004;350(9):886-95.
2004: Alan N Schechter; Robert L Perlman; Richard A Rettig
Why is revitalizing clinical research so important, yet so difficult?
Perspectives in biology and medicine 2004;47(4):476-86.
2003: Kenyatta Cosby; Kristine S Partovi; Jack H Crawford; Rakesh P Patel; Christopher D Reiter; Sabrina Martyr; Benjamin K Yang; Myron A Waclawiw; Gloria Zalos; Xiuli Xu; Kris T Huang; Howard Shields; Daniel B Kim-Shapiro; Alan N Schechter; Richard O Cannon; Mark T Gladwin
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.
Nature medicine 2003;9(12):1498-505.
2003: Karen M Byrne; Susan F Leitman; Alan N Schechter; David F Stroncek
Increasing oxygen tension improves filtration of sickle trait donor blood.
British journal of haematology 2003;122(4):678-81.
2003: Mark T Gladwin; Jack R Lancaster; Bruce Freeman; Alan N Schechter
Nitric oxide's reactions with hemoglobin: a view through the SNO-storm.
Nature medicine 2003;9(5):496-500.
2003: Mark T Gladwin; Alan N Schechter; Frederick P Ognibene; Wynona A Coles; Christopher D Reiter; William H Schenke; Gyorgy Csako; Myron A Waclawiw; Julio A Panza; Richard O Cannon
Divergent nitric oxide bioavailability in men and women with sickle cell disease.
Circulation 2003;107(2):271-8.
2003: Reginald D Smith; Benjamin Brown; Pranvera Ikonomi; Alan N Schechter
Exogenous reference RNA for normalization of real-time quantitative PCR.
BioTechniques 2003;34(1):88-91.
2003: Vladan P Cokic; Reginald D Smith; Bojana B Beleslin-Cokic; Joyce M Njoroge; Jeffery L Miller; Mark T Gladwin; Alan N Schechter
Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase.
The Journal of clinical investigation 2003;111(2):231-9.
2002: Christopher D Reiter; Xunde Wang; Jose E Tanus-Santos; Neil Hogg; Richard O Cannon; Alan N Schechter; Mark T Gladwin
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.
Nature medicine 2002;8(12):1383-9.
2002: David F Stroncek; Tobie Rainer; Victoria Sharon; Karen M Byrne; Constance Tom Noguchi; HARVEY KLEIN; Alan N Schechter; Susan F Leitman
Sickle Hb polymerization in RBC components from donors with sickle cell trait prevents effective WBC reduction by filtration.
Transfusion 2002;42(11):1466-72.
2002: Xiuli Xu; Virginia L Lockamy; Kejing Chen; Zhi Huang; Howard Shields; S Bruce King; Samir K Ballas; James S Nichols; Mark T Gladwin; Constance Tom Noguchi; Alan N Schechter; Daniel B Kim-Shapiro
Effects of iron nitrosylation on sickle cell hemoglobin solubility.
The Journal of biological chemistry 2002;277(39):36787-92.
2002: Alan N Schechter; Richard A Rettig
Funding priorities for medical research.
JAMA : the journal of the American Medical Association 2002;288(7):832; author reply 832.
2002: Mark T Gladwin; Xunde Wang; Christopher D Reiter; Benjamin K Yang; Esther X Vivas; Celia Bonaventura; Alan N Schechter
S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function.
The Journal of biological chemistry 2002;277(31):27818-28.
2002: Alan N Schechter; Mark T Gladwin; Richard O Cannon
NO solutions?
The Journal of clinical investigation 2002;109(9):1149-51.
2002: Alan N Schechter
Prematurity in gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(3):217-9.
2002: Mark T Gladwin; James H Shelhamer; Frederick P Ognibene; Margaret E Pease-Fye; James S Nichols; Beth Link; Daksesh B Patel; Marcin A Jankowski; Lewis K Pannell; Alan N Schechter; Griffin P Rodgers
Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease.
British journal of haematology 2002;116(2):436-44.
2001: Constance Tom Noguchi; Mark T Gladwin; B Diwan; P Merciris; R Smith; Xiaobing Yu; Gregory S Buzard; Anthony L Fitzhugh; Larry K Keefer; Alan N Schechter; N Mohandas
Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele.
Blood cells, molecules & diseases 2001;27(6):971-7.
2001: Mark T Gladwin; Frederick P Ognibene; James H Shelhamer; Margaret E Pease-Fye; Constance Tom Noguchi; Griffin P Rodgers; Alan N Schechter
Nitric oxide transport on sickle cell hemoglobin: where does it bind?
Free radical research 2001;35(2):175-80.
2001: Richard O Cannon; Alan N Schechter; Julio A Panza; Frederick P Ognibene; Margaret E Pease-Fye; Myron A Waclawiw; James H Shelhamer; Mark T Gladwin
Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery.
The Journal of clinical investigation 2001;108(2):279-87.
2001: Hiroshi Taniuchi; Y Shi; G I San Miguel; James A Ferretti; James W Mack; A Fisher; M Shah; Alan N Schechter; Joseph Shiloach
A study of the influence of the hydrophobic core residues of yeast iso-2-cytochrome c on phosphate binding: a probe of the hydrophobic core-surface charge interactions.
Journal of protein chemistry 2001;20(3):203-15.
2001: Sukru Tuzmen; Alan N Schechter
Genetic diseases of hemoglobin: diagnostic methods for elucidating beta-thalassemia mutations.
Blood reviews 2001;15(1):19-29.
2001: Traci Heath Mondoro; B B Ryan; BW Hrinczenko; Alan N Schechter; Jaroslav G Vostal; Abdu I Alayash
Biological action of nitric oxide donor compounds on platelets from patients with sickle cell disease.
British journal of haematology 2001;112(4):1048-54.
2000: Pranvera Ikonomi; Constance Tom Noguchi; W Miller; H Kassahun; Ross C Hardison; Alan N Schechter
Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins.
Gene 2000;261(2):277-87.
2000: Reginald D Smith; J D Malley; Alan N Schechter
Quantitative analysis of globin gene induction in single human erythroleukemic cells.
Nucleic acids research 2000;28(24):4998-5004.
2000: Pranvera Ikonomi; C E Rivera; M Riordan; G Washington; Alan N Schechter; Constance Tom Noguchi
Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation.
Experimental hematology 2000;28(12):1423-31.
2000: Mark T Gladwin; James H Shelhamer; Alan N Schechter; Margaret E Pease-Fye; Myron A Waclawiw; Julio A Panza; Frederick P Ognibene; Richard O Cannon
Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11482-7.
2000: BW Hrinczenko; Alan N Schechter; T L Wojtkowski; Lewis K Pannell; RE Cashon; Abdu I Alayash
Nitric oxide-mediated heme oxidation and selective beta-globin nitrosation of hemoglobin from normal and sickle erythrocytes.
Biochemical and biophysical research communications 2000;275(3):962-7.
2000: Mark T Gladwin; Frederick P Ognibene; Lewis K Pannell; James S Nichols; Margaret E Pease-Fye; James H Shelhamer; Alan N Schechter
Relative role of heme nitrosylation and beta-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):9943-8.
2000: BW Hrinczenko; Abdu I Alayash; D A Wink; Mark T Gladwin; Griffin P Rodgers; Alan N Schechter
Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport.
British journal of haematology 2000;110(2):412-9.
2000: Reginald D Smith; J Li; Constance Tom Noguchi; Alan N Schechter
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
Blood 2000;95(3):863-9.
1999: Mark T Gladwin; Alan N Schechter; James H Shelhamer; Lewis K Pannell; D A Conway; BW Hrinczenko; James S Nichols; Margaret E Pease-Fye; Constance Tom Noguchi; Griffin P Rodgers; Frederick P Ognibene
Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity.
The Journal of clinical investigation 1999;104(7):937-45.
1999: Mark T Gladwin; Alan N Schechter; James H Shelhamer; Frederick P Ognibene
The acute chest syndrome in sickle cell disease. Possible role of nitric oxide in its pathophysiology and treatment.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1368-76.
1998: J Li; Constance Tom Noguchi; W Miller; Ross C Hardison; Alan N Schechter
Multiple regulatory elements in the 5'-flanking sequence of the human epsilon-globin gene.
The Journal of biological chemistry 1998;273(17):10202-9.
1998: S Hasegawa; Griffin P Rodgers; Nancy K Dwyer; Constance Tom Noguchi; E Joan Blanchette-Mackie; N Uyesaka; Alan N Schechter; Eitan Fibach
Sickling of nucleated erythroid precursors from patients with sickle cell anemia.
Experimental hematology 1998;26(4):314-9.
1996: Panagoula Kollia; E Fibach; Sonia M Najjar; Alan N Schechter; C T Noguchi
Modifications of RNA processing modulate the expression of hemoglobin genes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):5693-8.
1995: S Hasegawa; H Hiruma; Nobuhiro Uyesaka; Constance Tom Noguchi; Alan N Schechter; Griffin P Rodgers
Filterability of mixtures of sickle and normal erythrocytes.
American journal of hematology 1995;50(2):91-7.
1995: Y T Zeng; S Z Huang; Z R Ren; Z H Lu; Fu-Yue Zeng; Alan N Schechter; Griffin P Rodgers
Hydroxyurea therapy in beta-thalassaemia intermedia: improvement in haematological parameters due to enhanced beta-globin synthesis.
British journal of haematology 1995;90(3):557-63.
1995: Eitan Fibach; Panagoula Kollia; Alan N Schechter; C T Noguchi; G P Rodgers
Hemin-induced acceleration of hemoglobin production in immature cultured erythroid cells: preferential enhancement of fetal hemoglobin.
Blood 1995;85(10):2967-74.
1995: H Hiruma; Constance Tom Noguchi; Nobuhiro Uyesaka; Alan N Schechter; Griffin P Rodgers
Contributions of sickle hemoglobin polymer and sickle cell membranes to impaired filterability.
The American journal of physiology 1995;268(5 Pt 2):H2003-8.
1995: H Hiruma; Constance Tom Noguchi; Nobuhiro Uyesaka; S Hasegawa; E J Blanchette-Mackie; Alan N Schechter; Griffin P Rodgers
Sickle cell rheology is determined by polymer fraction--not cell morphology.
American journal of hematology 1995;48(1):19-28.
1994: S Z Huang; Z R Ren; M J Chen; H P Xu; Y T Zeng; Griffin P Rodgers; Fu-Yue Zeng; Alan N Schechter
Treatment of beta-thalassemia with hydroxyurea (HU)--effects of HU on globin gene expression.
Science in China. Series B, Chemistry, life sciences & earth sciences 1994;37(11):1350-9.
1994: S Z Huang; Fu-Yue Zeng; Z R Ren; Z H Lu; Griffin P Rodgers; Alan N Schechter; Y T Zeng
RNA transcripts of the beta-thalassaemia allele IVS-2-654 C-->T: a small amount of normally processed beta-globin mRNA is still produced from the mutant gene.
British journal of haematology 1994;88(3):541-6.
1994: Eitan Fibach; Alan N Schechter; C T Noguchi; G P Rodgers
Reducing erythropoietin in cultures of human erythroid precursors elevates the proportion of fetal haemoglobin.
British journal of haematology 1994;88(1):39-45.
1994: Fu-Yue Zeng; Griffin P Rodgers; S Z Huang; Alan N Schechter; M Salamah; S Perrine; P E Berg
Sequence of the -530 region of the beta-globin gene of sickle cell anemia patients with the Arabian haplotype.
Human mutation 1994;3(2):163-5.
1993: S Hasegawa; Griffin P Rodgers; H Shio; Alan N Schechter; Nobuhiro Uyesaka
Impaired deformability of Heinz body-forming red cells.
Biorheology 1993;30(3-4):275-86.
1993: Eitan Fibach; L P Burke; Alan N Schechter; C T Noguchi; G P Rodgers
Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia.
Blood 1993;81(6):1630-5.
1993: Constance Tom Noguchi; Alan N Schechter; Griffin P Rodgers
Sickle cell disease pathophysiology.
Baillière's clinical haematology 1993;6(1):57-91.
1993: Griffin P Rodgers; George J Dover; Nobuhiro Uyesaka; Constance Tom Noguchi; Alan N Schechter; A W Nienhuis
Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease.
The New England journal of medicine 1993;328(2):73-80.
1992: C Dong; R S Chadwick; Alan N Schechter
Influence of sickle hemoglobin polymerization and membrane properties on deformability of sickle erythrocytes in the microcirculation.
Biophysical journal 1992;63(3):774-83.
1992: S Z Huang; Griffin P Rodgers; Fu-Yue Zeng; Y T Zeng; Alan N Schechter
Diagnosis of thalassemia using cDNA amplification of circulating erythroid cell mRNA with the polymerase chain reaction.
Blood 1992;79(12):3397.
1992: Nobuhiro Uyesaka; S Hasegawa; N Ishioka; R Ishioka; H Shio; Alan N Schechter
Effects of superoxide anions on red cell deformability and membrane proteins.
Biorheology 1992;29(2-3):217-29.
1992: Jacques Elion; P E Berg; Claudine Lapouméroulie; G Trabuchet; M Mittelman; Rajagopal Krishnamoorthy; Alan N Schechter; Dominique Labie
DNA sequence variation in a negative control region 5' to the beta-globin gene correlates with the phenotypic expression of the beta s mutation.
Blood 1992;79(3):787-92.
1992: P D Gutman; S X Cao; H P Dave; M Mittelman; Alan N Schechter
Binding of erythroid and non-erythroid nuclear proteins to the silencer of the human epsilon-globin-encoding gene.
Gene 1992;110(2):197-203.
1992: P E Berg; Alan N Schechter
The impact of molecular biology on the diagnosis and treatment of hemoglobin disorders.
Molecular genetic medicine 1992;2():1-38.
1991: Constance Tom Noguchi; K S Bae; K Chin; Y Wada; Alan N Schechter; William David Hankins
Cloning of the human erythropoietin receptor gene.
Blood 1991;78(10):2548-56.
1991: S Z Huang; Griffin P Rodgers; Fu-Yue Zeng; Y T Zeng; Alan N Schechter
Diagnosis of thalassemia using cDNA amplification of circulating erythroid cell mRNA with the polymerase chain reaction.
Blood 1991;78(9):2433-7.
1991: P E Berg; M Mittelman; Jacques Elion; Dominique Labie; Alan N Schechter
Increased protein binding to a -530 mutation of the human beta-globin gene associated with decreased beta-globin synthesis.
American journal of hematology 1991;36(1):42-7.
1990: Griffin P Rodgers; George J Dover; Constance Tom Noguchi; Alan N Schechter; A W Nienhuis
Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea.
The New England journal of medicine 1990;322(15):1037-45.
1990: Griffin P Rodgers; Alan N Schechter; Constance Tom Noguchi; HARVEY KLEIN; A W Nienhuis; Robert F Bonner
Microcirculatory adaptations in sickle cell anemia: reactive hyperemia response.
The American journal of physiology 1990;258(1 Pt 2):H113-20.
1989: H B Fox; P D Gutman; H P Dave; S X Cao; M Mittelman; P E Berg; Alan N Schechter
Trans-activation of human globin genes by HTLV-I tax1.
Blood 1989;74(8):2749-54.
1989: P E Berg; D M Williams; R L Qian; R B Cohen; S X Cao; M Mittelman; Alan N Schechter
A common protein binds to two silencers 5' to the human beta-globin gene.
Nucleic acids research 1989;17(21):8833-52.
1989: S X Cao; P D Gutman; H P Dave; Alan N Schechter
Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5306-9.
1989: S X Cao; H Mishoe; Jacques Elion; P E Berg; Alan N Schechter
Activation of the human epsilon- and beta-globin promoters by SV40 T antigen.
The Biochemical journal 1989;258(3):769-76.
1989: Griffin P Rodgers; Constance Tom Noguchi; Alan N Schechter
Hemodynamic studies in sickle cell disease.
Annals of the New York Academy of Sciences 1989;565():338-46.
1989: H P Dave; P D Gutman; S X Cao; Alan N Schechter
Induction of hemoglobin synthesis in the human leukemia cell line, SPI-802.
Progress in clinical and biological research 1989;316B():209-18.
1989: S X Cao; P D Gutman; H P Dave; Alan N Schechter
Negative control of the human epsilon-globin gene.
Progress in clinical and biological research 1989;316A():279-89.
1989: P E Berg; D M Williams; R L Qian; R B Cohen; M Mittelman; Alan N Schechter
Proteins binding to regulatory elements 5' to the human beta-globin gene.
Progress in clinical and biological research 1989;316A():193-202.
1989: Griffin P Rodgers; George J Dover; Constance Tom Noguchi; Alan N Schechter; A W Nienhuis
Induction of fetal hemoglobin in sickle cell patients by hydroxyurea: the N.I.H. experience.
Progress in clinical and biological research 1989;316B():281-93.
1989: Constance Tom Noguchi; Griffin P Rodgers; Alan N Schechter
Intracellular polymerization. Disease severity and therapeutic predictions.
Annals of the New York Academy of Sciences 1989;565():75-82.
1988: S X Cao; Alan N Schechter
Nuclease hypersensitivity in the beta-globin gene region of K562 cells.
European journal of biochemistry / FEBS 1988;173(3):517-22.
1988: Griffin P Rodgers; M S Roy; Constance Tom Noguchi; Alan N Schechter
Is there a role for selective vasodilation in the management of sickle cell disease?
Blood 1988;71(3):597-602.
1988: Constance Tom Noguchi; Griffin P Rodgers; G Serjeant; Alan N Schechter
Levels of fetal hemoglobin necessary for treatment of sickle cell disease.
The New England journal of medicine 1988;318(2):96-9.
1988: C Acquaye; E J Blanchette-Mackie; C Reindorf; S Edelstein; Alan N Schechter
Electron microscopic studies of the intracellular polymerization of sickle hemoglobin.
Blood cells 1988;13(3):359-76.
1988: Griffin P Rodgers; M S Roy; Constance Tom Noguchi; Alan N Schechter
Use of selective vasodilation in treatment of sickle cell disease.
The American journal of pediatric hematology/oncology 1988;10(4):351-6.
1987: Constance Tom Noguchi; Griffin P Rodgers; G Serjeant; Alan N Schechter
Predicting therapeutic efficacy for sickle cell anemia.
Progress in clinical and biological research 1987;251():497-505.