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JW Scheeren

Research Profile

Disorders

Chemicals & Drugs

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Tumor Cells, Cultured

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Publications

TOP 3
PH Houba; Epie Boven; Ida H van der Meulen-Muileman; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.
PH Houba; Epie Boven; Ida H van der Meulen-Muileman; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer.
PH Houba; Epie Boven; Ida H van der Meulen-Muileman; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts.

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All Publications

2001: PH Houba; Epie Boven; Ida H van der Meulen-Muileman; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.
International journal of cancer. Journal international du cancer 2001;91(4):550-4.
2001: PH Houba; Epie Boven; Ida H van der Meulen-Muileman; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer.
British journal of cancer 2001;84(4):550-7.
1999: PH Houba; Epie Boven; Ida H van der Meulen-Muileman; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts.
Biochemical pharmacology 1999;57(6):673-80.
1998: PH Houba; Epie Boven; C A M Erkelens; RG Leenders; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
The efficacy of the anthracycline prodrug daunorubicin-GA3 in human ovarian cancer xenografts.
British journal of cancer 1998;78(12):1600-6.
1996: PH Houba; RG Leenders; Epie Boven; JW Scheeren; HERBERT PINEDO; Hidde J Haisma
Characterization of novel anthracycline prodrugs activated by human beta-glucuronidase for use in antibody-directed enzyme prodrug therapy.
Biochemical pharmacology 1996;52(3):455-63.

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