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Randy Schekman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Living Beings

Saccharomyces cerevisiae

Chemicals & Drugs

Physiology

Genes & Molecular Sequences

Concepts & Ideas

Molecular Sequence Data

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Co-Publications
Name
22
Hamamoto, Susan
16
Orci, Lelio
11
Ravazzola, Mariella
6
Amherdt, Mylene
5
Feldheim, David
5
Fromme, Christopher
5
Matsuoka, K
5
Hicke, Linda
5
Lee, Marcus
5
Malkus, Per
5
Spang, Anne
4
Perrelet, Alain
4
Springer, Sebastian
4
Kim, Jinoh
4
Antonny, Bruno

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Publications

TOP 3
Schekman Randy
Change is good: life outside the nucleus.
Schindler Adam J; Schekman Randy
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles.
Tran John H; Chen Ching-Jen; Emr Scott; Schekman Randy
Cargo sorting into multivesicular bodies in vitro.

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All Publications

2009: Schekman Randy
Change is good: life outside the nucleus.
Nature cell biology 2009;11(11):1274.
2009: Schindler Adam J; Schekman Randy
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17775-80.
2009: Tran John H; Chen Ching-Jen; Emr Scott; Schekman Randy
Cargo sorting into multivesicular bodies in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17395-400.
2009: Schekman Randy
PNAS takes action regarding breach of NIH embargo policy on a PNAS paper.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(40):16893.
2009: Saito Kota; Chen Mei; Bard Fred; Chen Shenghong; Zhou Huilin; Woodley David; Polischuk Roman; Schekman Randy; Malhotra Vivek
TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites.
Cell 2009;136(5):891-902.
2008: Wickner William; Schekman Randy
Membrane fusion.
Nature structural & molecular biology 2008;15(7):658-64.
2008: Fromme J Christopher; Orci Lelio; Schekman Randy
Coordination of COPII vesicle trafficking by Sec23.
Trends in cell biology 2008;18(7):330-6.
2008: Schekman Randy
Expression of concern.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7893.
2008: Schekman Randy
Expression of concern.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7893.
2008: Schekman Randy
Expression of concern.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7893.
2008: Scott Daniel C; Schekman Randy
Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins.
The Journal of cell biology 2008;181(7):1095-105.
2007: Kim Jinoh; Kleizen Bertrand; Choy Regina; Thinakaran Gopal; Sisodia Sangram S; Schekman Randy W
Biogenesis of gamma-secretase early in the secretory pathway.
The Journal of cell biology 2007;179(5):951-63.
2007: Fromme J Christopher; Ravazzola Mariella; Hamamoto Susan; Al-Balwi Mohammed; Eyaid Wafaa; Boyadjiev Simeon A; Cosson Pierre; Schekman Randy; Orci Lelio
The genetic basis of a craniofacial disease provides insight into COPII coat assembly.
Developmental cell 2007;13(5):623-34.
2007: Kim Jinoh; Thanabalasuriar Ajitha; Chaworth-Musters Tessa; Fromme J Chris; Frey Elizabeth A; Lario Paula I; Metalnikov Pavel; Rizg Keyrillos; Thomas Nikhil A; Lee Sau Fung; Hartland Elizabeth L; Hardwidge Philip R; Pawson Tony; Strynadka Natalie C; Finlay B Brett; Schekman Randy; Gruenheid Samantha
The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function.
Cell host & microbe 2007;2(3):160-71.
2007: Schekman Randy
The nine lives of Daniel E. Koshland, Jr. (1920-2007).
Proceedings of the National Academy of Sciences of the United States of America 2007;104(37):14551-2.
2007: Copic Alenka; Starr Trevor L; Schekman Randy
Ent3p and Ent5p exhibit cargo-specific functions in trafficking proteins between the trans-Golgi network and the endosomes in yeast.
Molecular biology of the cell 2007;18(5):1803-15.
2007: Schekman Randy
How sterols regulate protein sorting and traffic.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6496-7.
2007: Harsay Edina; Schekman Randy
Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway.
Molecular biology of the cell 2007;18(4):1203-19.
2006: Schekman Randy
QnAs with Randy Schekman. [Interview by Nick Zagorski]
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):18881.
2006: Boyadjiev Simeon A; Fromme J Christopher; Ben Jin; Chong Samuel S; Nauta Christopher; Hur David J; Zhang George; Hamamoto Susan; Schekman Randy; Ravazzola Mariella; Orci Lelio; Eyaid Wafaa
Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking.
Nature genetics 2006;38(10):1192-7.
2006: Sanchatjate Siraprapha; Schekman Randy
Chs5/6 complex: a multiprotein complex that interacts with and conveys chitin synthase III from the trans-Golgi network to the cell surface.
Molecular biology of the cell 2006;17(10):4157-66.
2006: Wang Chao-Wen; Hamamoto Susan; Orci Lelio; Schekman Randy
Exomer: A coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.
The Journal of cell biology 2006;174(7):973-83.
2005: Wickner William; Schekman Randy
Protein translocation across biological membranes.
Science (New York, N.Y.) 2005;310(5753):1452-6.
2005: Lee Marcus C S; Orci Lelio; Hamamoto Susan; Futai Eugene; Ravazzola Mariella; Schekman Randy
Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle.
Cell 2005;122(4):605-17.
2005: Fromme J Christopher; Schekman Randy
COPII-coated vesicles: flexible enough for large cargo?
Current opinion in cell biology 2005;17(4):345-52.
2005: Miller Elizabeth A; Liu Yiting; Barlowe Charles; Schekman Randy
ER-Golgi transport defects are associated with mutations in the Sed5p-binding domain of the COPII coat subunit, Sec24p.
Molecular biology of the cell 2005;16(8):3719-26.
2005: Schekman Randy
Peroxisomes: another branch of the secretory pathway?
Cell 2005;122(1):1-2.
2005: Kim Jinoh; Hamamoto Susan; Ravazzola Mariella; Orci Lelio; Schekman Randy
Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles.
The Journal of biological chemistry 2005;280(9):7758-68.
2005: Sun Yidi; Kaksonen Marko; Madden David T; Schekman Randy; Drubin David G
Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization.
Molecular biology of the cell 2005;16(2):717-30.
2005: Futai Eugene; Schekman Randy
Purification and functional properties of yeast Sec12 GEF.
Methods in enzymology 2005;404():74-82.
2004: Malkus Per; Graham Laurie A; Stevens Tom H; Schekman Randy
Role of Vma21p in assembly and transport of the yeast vacuolar ATPase.
Molecular biology of the cell 2004;15(11):5075-91.
2004: Futai Eugene; Hamamoto Susan; Orci Lelio; Schekman Randy
GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes.
The EMBO journal 2004;23(21):4146-55.
2004: Schekman Randy
Cell biology: a channel for protein waste.
Nature 2004;429(6994):817-8.
2004: Schekman Randy
Merging cultures in the study of membrane traffic.
Nature cell biology 2004;6(6):483-6.
2004: Schekman Randy; Novick Peter
23 genes, 23 years later.
Cell 2004;116(2 Suppl):S13-5, 1 p following S19.
2004: Lee Marcus C S; Schekman Randy
Cell biology. BAR domains go on a bender.
Science (New York, N.Y.) 2004;303(5657):479-80.
2004: Kim Jinoh; Schekman Randy
The ins and outs of presenilin 1 membrane topology.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(4):905-6.
2004: Lee Marcus C S; Miller Elizabeth A; Goldberg Jonathan; Orci Lelio; Schekman Randy
Bi-directional protein transport between the ER and Golgi.
Annual review of cell and developmental biology 2004;20():87-123.
2003: Valdivia Raphael H; Schekman Randy
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10287-92.
2003: Miller Elizabeth A; Beilharz Traude H; Malkus Per N; Lee Marcus C S; Hamamoto Susan; Orci Lelio; Schekman Randy
Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles.
Cell 2003;114(4):497-509.
2003: Antonny Bruno; Gounon Pierre; Schekman Randy; Orci Lelio
Self-assembly of minimal COPII cages.
EMBO reports 2003;4(4):419-24.
2002: Malkus Per; Jiang Feng; Schekman Randy
Concentrative sorting of secretory cargo proteins into COPII-coated vesicles.
The Journal of cell biology 2002;159(6):915-21.
2002: Deloche Olivier; Schekman Randy W
Vps10p cycles between the TGN and the late endosome via the plasma membrane in clathrin mutants.
Molecular biology of the cell 2002;13(12):4296-307.
2002: Miller Elizabeth; Antonny Bruno; Hamamoto Susan; Schekman Randy
Cargo selection into COPII vesicles is driven by the Sec24p subunit.
The EMBO journal 2002;21(22):6105-13.
2002: Schekman Randy
Lasker Basic Medical Research Award. SEC mutants and the secretory apparatus.
Nature medicine 2002;8(10):1055-8.
2002: Supek Frantisek; Madden David T; Hamamoto Susan; Orci Lelio; Schekman Randy
Sec16p potentiates the action of COPII proteins to bud transport vesicles.
The Journal of cell biology 2002;158(6):1029-38.
2002: Lee Marcus C S; Hamamoto Susan; Schekman Randy
Ceramide biosynthesis is required for the formation of the oligomeric H+-ATPase Pma1p in the yeast endoplasmic reticulum.
The Journal of biological chemistry 2002;277(25):22395-401.
2002: Valdivia Raphael H; Baggott Daniel; Chuang John S; Schekman Randy W
The yeast clathrin adaptor protein complex 1 is required for the efficient retention of a subset of late Golgi membrane proteins.
Developmental cell 2002;2(3):283-94.
2002: Harsay Edina; Schekman Randy
A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway.
The Journal of cell biology 2002;156(2):271-85.
2002: Shimoni Yuval; Schekman Randy
Vesicle budding from endoplasmic reticulum.
Methods in enzymology 2002;351():258-78.
2001: Matsuoka K; Schekman R; Orci L; Heuser J E
Surface structure of the COPII-coated vesicle.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13705-9.
2001: Lederkremer G Z; Cheng Y; Petre B M; Vogan E; Springer S; Schekman R; Walz T; Kirchhausen T
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10704-9.
2001: Antonny B; Schekman R
ER export: public transportation by the COPII coach.
Current opinion in cell biology 2001;13(4):438-43.
2001: Antonny B; Madden D; Hamamoto S; Orci L; Schekman R
Dynamics of the COPII coat with GTP and stable analogues.
Nature cell biology 2001;3(6):531-7.
2001: Spang A; Herrmann J M; Hamamoto S; Schekman R
The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum.
Molecular biology of the cell 2001;12(4):1035-45.
2001: Deloche O; Yeung B G; Payne G S; Schekman R
Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesicles.
Molecular biology of the cell 2001;12(2):475-85.
2000: Todorow Z; Spang A; Carmack E; Yates J; Schekman R
Active recycling of yeast Golgi mannosyltransferase complexes through the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13643-8.
2000: Shimoni Y; Kurihara T; Ravazzola M; Amherdt M; Orci L; Schekman R
Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae.
The Journal of cell biology 2000;151(5):973-84.
2000: Springer S; Chen E; Duden R; Marzioch M; Rowley A; Hamamoto S; Merchant S; Schekman R
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4034-9.
2000: Matsuoka K; Schekman R
The use of liposomes to study COPII- and COPI-coated vesicle formation and membrane protein sorting.
Methods (San Diego, Calif.) 2000;20(4):417-28.
2000: Kurihara T; Hamamoto S; Gimeno R E; Kaiser C A; Schekman R; Yoshihisa T
Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae.
Molecular biology of the cell 2000;11(3):983-98.
2000: Lau W T; Howson R W; Malkus P; Schekman R; O'Shea E K
Pho86p, an endoplasmic reticulum (ER) resident protein in Saccharomyces cerevisiae, is required for ER exit of the high-affinity phosphate transporter Pho84p.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1107-12.
1999: Zhou M; Schekman R
The engagement of Sec61p in the ER dislocation process.
Molecular cell 1999;4(6):925-34.
1999: Springer S; Spang A; Schekman R
A primer on vesicle budding.
Cell 1999;97(2):145-8.
1999: Herrmann J M; Malkus P; Schekman R
Out of the ER--outfitters, escorts and guides.
Trends in cell biology 1999;9(1):5-7.
1998: Pilon M; Römisch K; Quach D; Schekman R
Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane.
Molecular biology of the cell 1998;9(12):3455-73.
1998: Matsuoka K; Morimitsu Y; Uchida K; Schekman R
Coat assembly directs v-SNARE concentration into synthetic COPII vesicles.
Molecular cell 1998;2(5):703-8.
1998: Spang A; Schekman R
Reconstitution of retrograde transport from the Golgi to the ER in vitro.
The Journal of cell biology 1998;143(3):589-99.
1998: Spang A; Matsuoka K; Hamamoto S; Schekman R; Orci L
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11199-204.
1998: Springer S; Schekman R
Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs.
Science (New York, N.Y.) 1998;281(5377):698-700.
1998: Ziman M; Chuang J S; Tsung M; Hamamoto S; Schekman R
Chs6p-dependent anterograde transport of Chs3p from the chitosome to the plasma membrane in Saccharomyces cerevisiae.
Molecular biology of the cell 1998;9(6):1565-76.
1998: Matsuoka K; Orci L; Amherdt M; Bednarek S Y; Hamamoto S; Schekman R; Yeung T
COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes.
Cell 1998;93(2):263-75.
1998: Duden R; Kajikawa L; Wuestehube L; Schekman R
epsilon-COP is a structural component of coatomer that functions to stabilize alpha-COP.
The EMBO journal 1998;17(4):985-95.
1998: Kuehn M J; Herrmann J M; Schekman R
COPII-cargo interactions direct protein sorting into ER-derived transport vesicles.
Nature 1998;391(6663):187-90.
1997: Doering T L; Schekman R
Glycosyl-phosphatidylinositol anchor attachment in a yeast in vitro system.
The Biochemical journal 1997;328 ( Pt 2)():669-75.
1997: Pilon M; Schekman R; Römisch K
Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation.
The EMBO journal 1997;16(15):4540-8.
1997: Kuehn M J; Schekman R
COPII and secretory cargo capture into transport vesicles.
Current opinion in cell biology 1997;9(4):477-83.
1997: Schekman R; Mellman I
Does COPI go both ways?
Cell 1997;90(2):197-200.
1997: Corsi A K; Schekman R
The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiae.
The Journal of cell biology 1997;137(7):1483-93.
1997: Salama N R; Chuang J S; Schekman R W
Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum.
Molecular biology of the cell 1997;8(2):205-17.
1997: Campbell J L; Schekman R
Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):837-42.
1997: Lyman S K; Schekman R
Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP.
Cell 1997;88(1):85-96.
1996: Bednarek S Y; Orci L; Schekman R
Traffic COPs and the formation of vesicle coats.
Trends in cell biology 1996;6(12):468-73.
1996: Lyman S K; Schekman R
Polypeptide translocation machinery of the yeast endoplasmic reticulum.
Experientia 1996;52(12):1042-9.
1996: Ziman M; Chuang J S; Schekman R W
Chs1p and Chs3p, two proteins involved in chitin synthesis, populate a compartment of the Saccharomyces cerevisiae endocytic pathway.
Molecular biology of the cell 1996;7(12):1909-19.
1996: Corsi A K; Schekman R
Mechanism of polypeptide translocation into the endoplasmic reticulum.
The Journal of biological chemistry 1996;271(48):30299-302.
1996: Schekman R
Polypeptide translocation: a pretty picture is worth a thousand words.
Cell 1996;87(4):593-5.
1996: Chuang J S; Schekman R W
Differential trafficking and timed localization of two chitin synthase proteins, Chs2p and Chs3p.
The Journal of cell biology 1996;135(3):597-610.
1996: Kuehn M J; Schekman R; Ljungdahl P O
Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.
The Journal of cell biology 1996;135(3):585-95.
1996: Paccaud J P; Reith W; Carpentier J L; Ravazzola M; Amherdt M; Schekman R; Orci L
Cloning and functional characterization of mammalian homologues of the COPII component Sec23.
Molecular biology of the cell 1996;7(10):1535-46.
1996: Orci L; Schekman R; Perrelet A
Interleaflet clear space is reduced in the membrane of COP I and COP II-coated buds/vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):8968-70.
1996: Schekman R; Orci L
Coat proteins and vesicle budding.
Science (New York, N.Y.) 1996;271(5255):1526-33.
1996: Wuestehube L J; Duden R; Eun A; Hamamoto S; Korn P; Ram R; Schekman R
New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex.
Genetics 1996;142(2):393-406.
1996: Lupashin V V; Hamamoto S; Schekman R W
Biochemical requirements for the targeting and fusion of ER-derived transport vesicles with purified yeast Golgi membranes.
The Journal of cell biology 1996;132(3):277-89.
1996: Doering T L; Schekman R
GPI anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles.
The EMBO journal 1996;15(1):182-91.
1995: Bednarek S Y; Ravazzola M; Hosobuchi M; Amherdt M; Perrelet A; Schekman R; Orci L
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast.
Cell 1995;83(7):1183-96.
1995: Yeung T; Barlowe C; Schekman R
Uncoupled packaging of targeting and cargo molecules during transport vesicle budding from the endoplasmic reticulum.
The Journal of biological chemistry 1995;270(51):30567-70.
1995: Lyman S K; Schekman R
Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae.
The Journal of cell biology 1995;131(5):1163-71.
1995: Latterich M; Fröhlich K U; Schekman R
Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes.
Cell 1995;82(6):885-93.
1995: Salama N R; Schekman R W
The role of coat proteins in the biosynthesis of secretory proteins.
Current opinion in cell biology 1995;7(4):536-43.
1995: Schekman R; Barlowe C; Bednarek S; Campbell J; Doering T; Duden R; Kuehn M; Rexach M; Yeung T; Orci L
Coat proteins and selective protein packaging into transport vesicles.
Cold Spring Harbor symposia on quantitative biology 1995;60():11-21.
1995: Yeung T; Yoshihisa T; Schekman R
Purification of Sec23p-Sec24p complex.
Methods in enzymology 1995;257():145-51.
1994: Orci L; Perrelet A; Ravazzola M; Amherdt M; Rothman J E; Schekman R
Coatomer-rich endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):11924-8.
1994: Rexach M F; Latterich M; Schekman R W
Characteristics of endoplasmic reticulum-derived transport vesicles.
The Journal of cell biology 1994;126(5):1133-48.
1994: Duden R; Hosobuchi M; Hamamoto S; Winey M; Byers B; Schekman R
Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic.
The Journal of biological chemistry 1994;269(39):24486-95.
1994: Schekman R
Translocation gets a push.
Cell 1994;78(6):911-3.
1994: Feldheim D; Schekman R
Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex.
The Journal of cell biology 1994;126(4):935-43.
1994: Latterich M; Schekman R
The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion.
Cell 1994;78(1):87-98.
1994: Barlowe C; Orci L; Yeung T; Hosobuchi M; Hamamoto S; Salama N; Rexach M F; Ravazzola M; Amherdt M; Schekman R
COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum.
Cell 1994;77(6):895-907.
1993: Brodsky J L; Schekman R
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome.
The Journal of cell biology 1993;123(6 Pt 1):1355-63.
1993: Orci L; Perrelet A; Ravazzola M; Wieland F T; Schekman R; Rothman J E
"BFA bodies": a subcompartment of the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11089-93.
1993: Salama N R; Yeung T; Schekman R W
The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins.
The EMBO journal 1993;12(11):4073-82.
1993: Barlowe C; Schekman R
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER.
Nature 1993;365(6444):347-9.
1993: Feldheim D; Yoshimura K; Admon A; Schekman R
Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum.
Molecular biology of the cell 1993;4(9):931-9.
1993: Yoshihisa T; Barlowe C; Schekman R
Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum.
Science (New York, N.Y.) 1993;259(5100):1466-8.
1993: Pryer N K; Salama N R; Schekman R; Kaiser C A
Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.
The Journal of cell biology 1993;120(4):865-75.
1993: Barlowe C; d'Enfert C; Schekman R
Purification and characterization of SAR1p, a small GTP-binding protein required for transport vesicle formation from the endoplasmic reticulum.
The Journal of biological chemistry 1993;268(2):873-9.
1993: Brodsky J L; Hamamoto S; Feldheim D; Schekman R
Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70.
The Journal of cell biology 1993;120(1):95-102.
1992: Hosobuchi M; Kreis T; Schekman R
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer.
Nature 1992;360(6404):603-5.
1992: Römisch K; Schekman R
Distinct processes mediate glycoprotein and glycopeptide export from the endoplasmic reticulum in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7227-31.
1992: Schekman R
Genetic and biochemical analysis of vesicular traffic in yeast.
Current opinion in cell biology 1992;4(4):587-92.
1992: Feldheim D; Rothblatt J; Schekman R
Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation.
Molecular and cellular biology 1992;12(7):3288-96.
1992: Sanders S L; Schekman R
Polypeptide translocation across the endoplasmic reticulum membrane.
The Journal of biological chemistry 1992;267(20):13791-4.
1992: Hicke L; Yoshihisa T; Schekman R
Sec23p and a novel 105-kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the endoplasmic reticulum.
Molecular biology of the cell 1992;3(6):667-76.
1992: Sanders S L; Whitfield K M; Vogel J P; Rose M D; Schekman R W
Sec61p and BiP directly facilitate polypeptide translocation into the ER.
Cell 1992;69(2):353-65.
1992: Rexach M; d'Enfert C; Wuestehube L; Schekman R
Genes and proteins required for vesicular transport from the endoplasmic reticulum.
Antonie van Leeuwenhoek 1992;61(2):87-92.
1992: Stirling C J; Rothblatt J; Hosobuchi M; Deshaies R; Schekman R
Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum.
Molecular biology of the cell 1992;3(2):129-42.
1992: Pryer N K; Wuestehube L J; Schekman R
Vesicle-mediated protein sorting.
Annual review of biochemistry 1992;61():471-516.
1992: Hicke L; Yoshihisa T; Schekman R W
Purification of yeast Sec23 protein by complementation of mutant cell lysates deficient in endoplasmic reticulum-to-Golgi transport.
Methods in enzymology 1992;219():338-52.
1992: Rexach M F; Schekman R W
Use of sec mutants to define intermediates in protein transport from endoplasmic reticulum.
Methods in enzymology 1992;219():267-86.
1992: Wuestehube L J; Schekman R W
Reconstitution of transport from endoplasmic reticulum to Golgi complex using endoplasmic reticulum-enriched membrane fraction from yeast.
Methods in enzymology 1992;219():124-36.
1991: d'Enfert C; Barlowe C; Nishikawa S; Nakano A; Schekman R
Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum.
Molecular and cellular biology 1991;11(11):5727-34.
1991: Orci L; Ravazzola M; Meda P; Holcomb C; Moore H P; Hicke L; Schekman R
Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8611-5.
1991: d'Enfert C; Wuestehube L J; Lila T; Schekman R
Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER.
The Journal of cell biology 1991;114(4):663-70.
1991: Rexach M F; Schekman R W
Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles.
The Journal of cell biology 1991;114(2):219-29.
1991: Chiang H L; Schekman R
Regulated import and degradation of a cytosolic protein in the yeast vacuole.
Nature 1991;350(6316):313-8.
1991: Deshaies R J; Sanders S L; Feldheim D A; Schekman R
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex.
Nature 1991;349(6312):806-8.
1990: Deshaies R J; Schekman R
Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery.
Molecular and cellular biology 1990;10(11):6024-35.
1990: Silveira L A; Wong D H; Masiarz F R; Schekman R
Yeast clathrin has a distinctive light chain that is important for cell growth.
The Journal of cell biology 1990;111(4):1437-49.
1990: Hicke L; Schekman R
Molecular machinery required for protein transport from the endoplasmic reticulum to the Golgi complex.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(6):253-8.
1990: Kaiser C A; Schekman R
Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway.
Cell 1990;61(4):723-33.
1990: Sengstag C; Stirling C; Schekman R; Rine J
Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Molecular and cellular biology 1990;10(2):672-80.
1990: Baker D; Wuestehube L; Schekman R; Botstein D; Segev N
GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(1):355-9.
1989: Deshaies R J; Schekman R
SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum.
The Journal of cell biology 1989;109(6 Pt 1):2653-64.
1989: Rothblatt J A; Deshaies R J; Sanders S L; Daum G; Schekman R
Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast.
The Journal of cell biology 1989;109(6 Pt 1):2641-52.
1989: Franzusoff A; Schekman R
Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation.
The EMBO journal 1989;8(9):2695-702.
1989: Hicke L; Schekman R
Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro.
The EMBO journal 1989;8(6):1677-84.
1989: Bernstein M; Kepes F; Schekman R
Sec59 encodes a membrane protein required for core glycosylation in Saccharomyces cerevisiae.
Molecular and cellular biology 1989;9(3):1191-9.
1989: Rothblatt J; Schekman R
A hitchhiker's guide to analysis of the secretory pathway in yeast.
Methods in cell biology 1989;32():3-36.
1989: Baker D; Schekman R
Reconstitution of protein transport using broken yeast spheroplasts.
Methods in cell biology 1989;31():127-41.
1988: Nakano A; Brada D; Schekman R
A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast.
The Journal of cell biology 1988;107(3):851-63.
1988: Achstetter T; Franzusoff A; Field C; Schekman R
SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.
The Journal of biological chemistry 1988;263(24):11711-7.
1988: Baker D; Hicke L; Rexach M; Schleyer M; Schekman R
Reconstitution of SEC gene product-dependent intercompartmental protein transport.
Cell 1988;54(3):335-44.
1988: Kepes F; Schekman R
The yeast SEC53 gene encodes phosphomannomutase.
The Journal of biological chemistry 1988;263(19):9155-61.
1988: Brada D; Schekman R
Coincident localization of secretory and plasma membrane proteins in organelles of the yeast secretory pathway.
Journal of bacteriology 1988;170(6):2775-83.
1988: Payne G S; Baker D; van Tuinen E; Schekman R
Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast.
The Journal of cell biology 1988;106(5):1453-61.
1988: Böhni P C; Deshaies R J; Schekman R W
SEC11 is required for signal peptide processing and yeast cell growth.
The Journal of cell biology 1988;106(4):1035-42.
1988: Deshaies R J; Koch B D; Werner-Washburne M; Craig E A; Schekman R
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides.
Nature 1988;332(6167):800-5.
1988: Holcomb C L; Hansen W J; Etcheverry T; Schekman R
Secretory vesicles externalize the major plasma membrane ATPase in yeast.
The Journal of cell biology 1988;106(3):641-8.
1987: Holcomb C L; Etcheverry T; Schekman R
Isolation of secretory vesicles from Saccharomyces cerevisiae.
Analytical biochemistry 1987;166(2):328-34.
1987: Payne G S; Hasson T B; Hasson M S; Schekman R
Genetic and biochemical characterization of clathrin-deficient Saccharomyces cerevisiae.
Molecular and cellular biology 1987;7(11):3888-98.

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