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Michael Schelle

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Publications

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Sarah A Gilmore; Cynthia M Holsclaw; Madhulika Jain; Julie A Leary; Clifton D Leigh; Michael W Schelle; Jeffery S Cox; Carolyn R Bertozzi
Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages.
Jessica C Seeliger; Sarah E Tully; Zsofia Botyanszki; Benjamin F Cravatt; Sarah A Gilmore; Cynthia M Holsclaw; Julie A Leary; Michael Niederweis; Michael W Schelle; Carolyn R Bertozzi
Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis.
Stavroula K Hatzios; Cynthia M Holsclaw; Gerald L Newton; Michael W Schelle; Kimberly M Sogi; Robert C Fahey; Carolyn R Bertozzi
The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth.

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All Publications

2012: Sarah A Gilmore; Cynthia M Holsclaw; Madhulika Jain; Julie A Leary; Clifton D Leigh; Michael W Schelle; Jeffery S Cox; Carolyn R Bertozzi
Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages.
ACS chemical biology 2012;7(5):863-70.
2012: Jessica C Seeliger; Sarah E Tully; Zsofia Botyanszki; Benjamin F Cravatt; Sarah A Gilmore; Cynthia M Holsclaw; Julie A Leary; Michael Niederweis; Michael W Schelle; Carolyn R Bertozzi
Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis.
The Journal of biological chemistry 2012;287(11):7990-8000.
2011: Stavroula K Hatzios; Cynthia M Holsclaw; Gerald L Newton; Michael W Schelle; Kimberly M Sogi; Robert C Fahey; Carolyn R Bertozzi
The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth.
Bioorganic & medicinal chemistry letters 2011;21(17):4956-9.
2009: Gregory T Crimmins; Michael W Schelle; Anat Herskovits; Peggy P Ni; Benjamin C Kline; Nicole Meyer-Morse; Anthony T Iavarone; Daniel A Portnoy
Listeria monocytogenes 6-Phosphogluconolactonase mutants induce increased activation of a host cytosolic surveillance pathway.
Infection and immunity 2009;77(7):3014-22.
2009: Stavroula K Hatzios; Michael W Schelle; Cynthia M Holsclaw; Christopher R Behrens; Zsofia Botyanszki; Fiona L Lin; Brian L Carlson; Pawan Kumar; Julie A Leary; Carolyn R Bertozzi
PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis.
The Journal of biological chemistry 2009;284(19):12745-51.
2008: Jennifer L Czlapinski; Michael W Schelle; Lawrence Miller; Scott T Laughlin; Jennifer Kohler; Virginia W Cornish; Carolyn R Bertozzi
Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization.
Journal of the American Chemical Society 2008;130(40):13186-7.
2007: Pawan Kumar; Michael W Schelle; Madhulika Jain; Fiona L Lin; Christopher J Petzold; Michael D Leavell; Julie A Leary; Jeffery S Cox; Carolyn R Bertozzi
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11221-6.
2007: Madhulika Jain; Christopher J Petzold; Michael W Schelle; Michael D Leavell; Joseph D Mougous; Carolyn R Bertozzi; Julie A Leary; Jeffery S Cox
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5133-8.
2006: Michael W Schelle; Carolyn R Bertozzi
Sulfate metabolism in mycobacteria.
Chembiochem : a European journal of chemical biology 2006;7(10):1516-24.
2006: Joseph D Mougous; Ryan Senaratne; Christopher J Petzold; Madhulika Jain; Dong H Lee; Michael W Schelle; Michael D Leavell; Jeffery S Cox; Julie A Leary; Lee W Riley; Carolyn R Bertozzi
A sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):4258-63.
2006: Joseph D Mougous; Dong H Lee; Sarah C Hubbard; Michael W Schelle; David J Vocadlo; James M Berger; Carolyn R Bertozzi
Molecular basis for G protein control of the prokaryotic ATP sulfurylase.
Molecular cell 2006;21(1):109-22.
2004: Jennifer Kohler; Jennifer L Czlapinski; Scott T Laughlin; Michael W Schelle; Christopher L De Graffenried; Carolyn R Bertozzi
Directing flux in glycan biosynthetic pathways with a small molecule switch.
Chembiochem : a European journal of chemical biology 2004;5(10):1455-8.