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Elizabeth Blackburn

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
10
McEachern, Michael J.
8
Gilley, David
7
Greider, Carol
6
Li, Shang
6
Tzfati, Yehuda
5
Xu, Lifeng
5
Krauskopf, Anat
5
Makovets, Svetlana
5
Fulton, TB
4
Cawthon, Richard
4
Lin, Jue
4
Parslow, Tristram
4
Roy, Jagoree
4
Wang, Haiyang
4
Ly, Hinh

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Publications

TOP 3
Makovets Svetlana; Blackburn Elizabeth H
DNA damage signalling prevents deleterious telomere addition at DNA breaks.
Njajou Omer T; Hsueh Wen-Chi; Blackburn Elizabeth H; Newman Anne B; Wu Shih-Hsuan; Li Rongling; Simonsick Eleanor M; Harris Tamara M; Cummings Steve R; Cawthon Richard M;
Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study.
O'Donovan A; Lin J; Dhabhar F S; Wolkowitz O; Tillie J M; Blackburn E; Epel E
Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women.

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All Publications

2009: Makovets Svetlana; Blackburn Elizabeth H
DNA damage signalling prevents deleterious telomere addition at DNA breaks.
Nature cell biology 2009;11(11):1383-6.
2009: Njajou Omer T; Hsueh Wen-Chi; Blackburn Elizabeth H; Newman Anne B; Wu Shih-Hsuan; Li Rongling; Simonsick Eleanor M; Harris Tamara M; Cummings Steve R; Cawthon Richard M;
Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(8):860-4.
2009: O'Donovan A; Lin J; Dhabhar F S; Wolkowitz O; Tillie J M; Blackburn E; Epel E
Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women.
Brain, behavior, and immunity 2009;23(4):446-9.
2009: Li Shang; Makovets Svetlana; Matsuguchi Tetsuya; Blethrow Justin D; Shokat Kevan M; Blackburn Elizabeth H
Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.
Cell 2009;136(1):50-61.
2008: Ornish Dean; Lin Jue; Daubenmier Jennifer; Weidner Gerdi; Epel Elissa; Kemp Colleen; Magbanua Mark Jesus M; Marlin Ruth; Yglecias Loren; Carroll Peter R; Blackburn Elizabeth H
Increased telomerase activity and comprehensive lifestyle changes: a pilot study.
The lancet oncology 2008;9(11):1048-57.
2008: Seidel Jeffrey J; Anderson Carol M; Blackburn Elizabeth H
A novel Tel1/ATM N-terminal motif, TAN, is essential for telomere length maintenance and a DNA damage response.
Molecular and cellular biology 2008;28(18):5736-46.
2008: Stohr Bradley A; Blackburn Elizabeth H
ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells.
Cancer research 2008;68(13):5309-17.
2008: Anderson Carol M; Korkin Dmitry; Smith Dana L; Makovets Svetlana; Seidel Jeffrey J; Sali Andrej; Blackburn Elizabeth H
Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.
Genes & development 2008;22(7):854-9.
2008: Blackburn Elizabeth
Elizabeth Blackburn: because science is worth it. Interview by Ruth Williams.
The Journal of cell biology 2008;180(6):1056-7.
2008: Makovets Svetlana; Williams Tanya L; Blackburn Elizabeth H
The telotype defines the telomere state in Saccharomyces cerevisiae and is inherited as a dominant non-Mendelian characteristic in cells lacking telomerase.
Genetics 2008;178(1):245-57.
2008: Wang Xueying; Kam Zvi; Carlton Peter M; Xu Lifeng; Sedat John W; Blackburn Elizabeth H
Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy.
Epigenetics & chromatin 2008;1(1):4.
2007: Xu Lifeng; Blackburn Elizabeth H
Human cancer cells harbor T-stumps, a distinct class of extremely short telomeres.
Molecular cell 2007;28(2):315-27.
2007: Njajou Omer T; Cawthon Richard M; Damcott Coleen M; Wu Shih-Hsuan; Ott Sandy; Garant Michael J; Blackburn Elizabeth H; Mitchell Braxton D; Shuldiner Alan R; Hsueh Wen-Chi
Telomere length is paternally inherited and is associated with parental lifespan.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12135-9.
2007: Hsu Min; McEachern Michael J; Dandjinou Alain T; Tzfati Yehuda; Orr Erica; Blackburn Elizabeth H; Lue Neal F
Telomerase core components protect Candida telomeres from aberrant overhang accumulation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(28):11682-7.
2006: Blackburn Elizabeth H; Greider Carol W; Szostak Jack W
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.
Nature medicine 2006;12(10):1133-8.
2006: Blackburn E; Hiess A; Bernhoeft N; Rheinstädter M C; Häussler W; Lander G H
Fermi surface topology and the superconducting gap function in UPd2Al3: a neutron spin-echo study.
Physical review letters 2006;97(5):057002.
2006: Bagheri Sepideh; Nosrati Mehdi; Li Shang; Fong Sylvia; Torabian Sima; Rangel Javier; Moore Dan H; Federman Scot; Laposa Rebecca R; Baehner Frederick L; Sagebiel Richard W; Cleaver James E; Haqq Christopher; Debs Robert J; Blackburn Elizabeth H; Kashani-Sabet Mohammed
Genes and pathways downstream of telomerase in melanoma metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11306-11.
2006: Goldkorn Amir; Blackburn Elizabeth H
Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
Cancer research 2006;66(11):5763-71.
2006: Epel Elissa S; Lin Jue; Wilhelm Frank H; Wolkowitz Owen M; Cawthon Richard; Adler Nancy E; Dolbier Christyn; Mendes Wendy B; Blackburn Elizabeth H
Cell aging in relation to stress arousal and cardiovascular disease risk factors.
Psychoneuroendocrinology 2006;31(3):277-87.
2006: Li S; Blackburn E H
Expression and suppression of human telomerase RNA.
Cold Spring Harbor symposia on quantitative biology 2006;71():211-5.
2005: Blackburn Elizabeth H
Telomerase and Cancer: Kirk A. Landon--AACR prize for basic cancer research lecture.
Molecular cancer research : MCR 2005;3(9):477-82.
2005: Blackburn Elizabeth H
Cell biology: Shaggy mouse tales.
Nature 2005;436(7053):922-3.
2005: Ly Hinh; Schertzer Mike; Jastaniah Wasil; Davis Jeff; Yong Siu Li; Ouyang Qin; Blackburn Elizabeth H; Parslow Tristram G; Lansdorp Peter M
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita.
Blood 2005;106(4):1246-52.
2005: Li Shang; Crothers Julia; Haqq Christopher M; Blackburn Elizabeth H
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.
The Journal of biological chemistry 2005;280(25):23709-17.
2005: Blackburn Elizabeth H
Telomeres and telomerase: their mechanisms of action and the effects of altering their functions.
FEBS letters 2005;579(4):859-62.
2005: Blackburn Elizabeth
Stem cell science and politics: a talk with Elizabeth Blackburn.
Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees 2005;14(2):214-7.
2005: Blackburn Elizabeth
Thoughts of a former Council member.
Perspectives in biology and medicine 2005;48(2):172-80.
2004: Xu Lifeng; Blackburn Elizabeth H
Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules.
The Journal of cell biology 2004;167(5):819-30.
2004: Epel Elissa S; Blackburn Elizabeth H; Lin Jue; Dhabhar Firdaus S; Adler Nancy E; Morrow Jason D; Cawthon Richard M
Accelerated telomere shortening in response to life stress.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17312-5.
2004: Levy Daniel L; Blackburn Elizabeth H
Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length.
Molecular and cellular biology 2004;24(24):10857-67.
2004: Rivera Melissa A; Blackburn Elizabeth H
Processive utilization of the human telomerase template: lack of a requirement for template switching.
The Journal of biological chemistry 2004;279(51):53770-81.
2004: Lin Jue; Ly Hinh; Hussain Arif; Abraham Mira; Pearl Sivan; Tzfati Yehuda; Parslow Tristram G; Blackburn Elizabeth H
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(41):14713-8.
2004: Nosrati Mehdi; Li Shang; Bagheri Sepideh; Ginzinger David; Blackburn Elizabeth H; Debs Robert J; Kashani-Sabet Mohammed
Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):4983-90.
2004: Li Shang; Rosenberg Jonathan E; Donjacour Annemarie A; Botchkina Inna L; Hom Yun Kit; Cunha Gerald R; Blackburn Elizabeth H
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA.
Cancer research 2004;64(14):4833-40.
2004: Makovets Svetlana; Herskowitz Ira; Blackburn Elizabeth H
Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions.
Molecular and cellular biology 2004;24(9):4019-31.
2004: Blackburn Elizabeth
Bioethics and the political distortion of biomedical science.
The New England journal of medicine 2004;350(14):1379-80.
2004: Blackburn Elizabeth; Rowley Janet
Reason as our guide.
PLoS biology 2004;2(4):E116.
2004: Lin Jue; Smith Dana L; Blackburn Elizabeth H
Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response.
Molecular biology of the cell 2004;15(4):1623-34.
2004: Blackburn Elizabeth H
A 'full range' of bioethical views just got narrower.
Washington post (Washington, D.C. : 1974) 2004;():B2.
2004: Lin Jue; Blackburn Elizabeth H
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA.
Genes & development 2004;18(4):387-96.
2004: Chan Simon R W L; Blackburn Elizabeth H
Telomeres and telomerase.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1441):109-21.
2004: Greider Carol W; Blackburn Elizabeth H
Tracking telomerase.
Cell 2004;116(2 Suppl):S83-6, 1 p following S86.
2003: Seto Anita G; Umansky Kfir; Tzfati Yehuda; Zaug Arthur J; Blackburn Elizabeth H; Cech Thomas R
A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity.
RNA (New York, N.Y.) 2003;9(11):1323-32.
2003: Ly Hinh; Blackburn Elizabeth H; Parslow Tristram G
Comprehensive structure-function analysis of the core domain of human telomerase RNA.
Molecular and cellular biology 2003;23(19):6849-56.
2003: Kim Moses; Xu Lifeng; Blackburn Elizabeth H
Catalytically active human telomerase mutants with allele-specific biological properties.
Experimental cell research 2003;288(2):277-87.
2003: Tzfati Yehuda; Knight Zachary; Roy Jagoree; Blackburn Elizabeth H
A novel pseudoknot element is essential for the action of a yeast telomerase.
Genes & development 2003;17(14):1779-88.
2003: Chan Simon W-L; Blackburn Elizabeth H
Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining.
Molecular cell 2003;11(5):1379-87.
2003: Ly Hinh; Xu Lifeng; Rivera Melissa A; Parslow Tristram G; Blackburn Elizabeth H
A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase.
Genes & development 2003;17(9):1078-83.
2003: Smith C D; Smith D L; DeRisi J L; Blackburn E H
Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae.
Molecular biology of the cell 2003;14(2):556-70.
2002: Comolli Luis R; Smirnov Ivan; Xu Lifeng; Blackburn Elizabeth H; James Thomas L
A molecular switch underlies a human telomerase disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16998-7003.
2002: Seto Anita G; Livengood April J; Tzfati Yehuda; Blackburn Elizabeth H; Cech Thomas R
A bulged stem tethers Est1p to telomerase RNA in budding yeast.
Genes & development 2002;16(21):2800-12.
2002: Rowley Janet D; Blackburn Elizabeth; Gazzaniga Michael S; Foster Daniel W
Harmful moratorium on stem cell research.
Science (New York, N.Y.) 2002;297(5589):1957.
2002: Nautiyal Shivani; DeRisi Joseph L; Blackburn Elizabeth H
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9316-21.
2002: Chan Simon W-L; Blackburn Elizabeth H
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin.
Oncogene 2002;21(4):553-63.
2002: McEachern Michael J; Underwood Dana Hager; Blackburn Elizabeth H
Dynamics of telomeric DNA turnover in yeast.
Genetics 2002;160(1):63-73.
2002: Cano Maria Isabel N; Blake Julie Johnson; Blackburn Elizabeth H; Agabian Nina
A Trypanosoma brucei protein complex that binds G-overhangs and co-purifies with telomerase activity.
The Journal of biological chemistry 2002;277(2):896-906.
2001: Blackburn E H
Switching and signaling at the telomere.
Cell 2001;106(6):661-73.
2001: Chan S W; Chang J; Prescott J; Blackburn E H
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases.
Current biology : CB 2001;11(16):1240-50.
2001: Kim M M; Rivera M A; Botchkina I L; Shalaby R; Thor A D; Blackburn E H
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7982-7.
2000: Blackburn E H
Telomere states and cell fates.
Nature 2000;408(6808):53-6.
2000: Blackburn E H
The end of the (DNA) line.
Nature structural biology 2000;7(10):847-50.
2000: McEachern M J; Iyer S; Fulton T B; Blackburn E H
Telomere fusions caused by mutating the terminal region of telomeric DNA.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11409-14.
2000: Blackburn E H
Telomeres and telomerase.
The Keio journal of medicine 2000;49(2):59-65.
2000: Ware T L; Wang H; Blackburn E H
Three telomerases with completely non-telomeric template replacements are catalytically active.
The EMBO journal 2000;19(12):3119-31.
2000: Tzfati Y; Fulton T B; Roy J; Blackburn E H
Template boundary in a yeast telomerase specified by RNA structure.
Science (New York, N.Y.) 2000;288(5467):863-7.
2000: Prescott J C; Blackburn E H
Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres.
Molecular and cellular biology 2000;20(8):2941-8.
2000: Blackburn E H; Chan S; Chang J; Fulton T B; Krauskopf A; McEachern M; Prescott J; Roy J; Smith C; Wang H
Molecular manifestations and molecular determinants of telomere capping.
Cold Spring Harbor symposia on quantitative biology 2000;65():253-63.
2000: McEachern M J; Krauskopf A; Blackburn E H
Telomeres and their control.
Annual review of genetics 2000;34():331-358.
2000: Blackburn E; Gilley D; Ware T; Bhattacharyya A; Kirk K; Wang H
Studying the telomerase RNA in Tetrahymena.
Methods in cell biology 2000;62():417-32.
1999: Blackburn E
The telomere and telomerase: how Do they interact?
The Mount Sinai journal of medicine, New York 1999;66(5-6):292-300.
1999: Hsu H L; Gilley D; Blackburn E H; Chen D J
Ku is associated with the telomere in mammals.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12454-8.
1999: Prescott J C; Blackburn E H
Telomerase: Dr Jekyll or Mr Hyde?
Current opinion in genetics & development 1999;9(3):368-73.
1999: Gilley D; Blackburn E H
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6621-5.
1999: Smith C D; Blackburn E H
Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast.
The Journal of cell biology 1999;145(2):203-14.
1999: Zhu J; Wang H; Bishop J M; Blackburn E H
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3723-8.
1999: Cano M I; Dungan J M; Agabian N; Blackburn E H
Telomerase in kinetoplastid parasitic protozoa.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3616-21.
1998: Roy J; Fulton T B; Blackburn E H
Specific telomerase RNA residues distant from the template are essential for telomerase function.
Genes & development 1998;12(20):3286-300.
1998: Krauskopf A; Blackburn E H
Rap1 protein regulates telomere turnover in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12486-91.
1998: Fulton T B; Blackburn E H
Identification of Kluyveromyces lactis telomerase: discontinuous synthesis along the 30-nucleotide-long templating domain.
Molecular and cellular biology 1998;18(9):4961-70.
1998: Cohen P; Blackburn E H
Two types of telomeric chromatin in Tetrahymena thermophila.
Journal of molecular biology 1998;280(3):327-44.
1998: Frenck R W; Blackburn E H; Shannon K M
The rate of telomere sequence loss in human leukocytes varies with age.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5607-10.
1998: Gallagher R C; Blackburn E H
A promoter region mutation affecting replication of the Tetrahymena ribosomal DNA minichromosome.
Molecular and cellular biology 1998;18(5):3021-33.
1998: Hiraoka Y; Henderson E; Blackburn E H
Not so peculiar: fission yeast telomere repeats.
Trends in biochemical sciences 1998;23(4):126.
1998: Cohn M; McEachern M J; Blackburn E H
Telomeric sequence diversity within the genus Saccharomyces.
Current genetics 1998;33(2):83-91.
1998: Wang H; Gilley D; Blackburn E H
A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase.
The EMBO journal 1998;17(4):1152-60.
1997: Blackburn E H
The telomere and telomerase: nucleic acid-protein complexes acting in a telomere homeostasis system. A review.
Biochemistry. Biokhimii?a 1997;62(11):1196-201.
1997: Prescott J; Blackburn E H
Functionally interacting telomerase RNAs in the yeast telomerase complex.
Genes & development 1997;11(21):2790-800.
1997: Bhattacharyya A; Blackburn E H
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):2823-7.
1997: Bhattacharyya A; Blackburn E H
Aspergillus nidulans maintains short telomeres throughout development.
Nucleic acids research 1997;25(7):1426-31.
1997: Kirk K E; Harmon B P; Reichardt I K; Sedat J W; Blackburn E H
Block in anaphase chromosome separation caused by a telomerase template mutation.
Science (New York, N.Y.) 1997;275(5305):1478-81.
1997: Wang H; Blackburn E H
De novo telomere addition by Tetrahymena telomerase in vitro.
The EMBO journal 1997;16(4):866-79.
1997: Prescott J; Blackburn E H
Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro.
Genes & development 1997;11(4):528-40.
1997: Blackburn E; Bhattacharyya A; Gilley D; Kirk K; Krauskopf A; McEachern M; Prescott J; Ware T
The telomere and telomerase: how do they interact?
Ciba Foundation symposium 1997;211():2-13; discussion 15-9.
1996: Krauskopf A; Blackburn E H
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats.
Nature 1996;383(6598):354-7.
1996: McEachern M J; Blackburn E H
Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase.
Genes & development 1996;10(14):1822-34.
1996: Greider C W; Blackburn E H
Telomeres, telomerase and cancer.
Scientific American 1996;274(2):92-7.
1996: Gilley D; Blackburn E H
Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase.
Molecular and cellular biology 1996;16(1):66-75.
1996: Strahl C; Blackburn E H
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.
Molecular and cellular biology 1996;16(1):53-65.
1995: Gilley D; Lee M S; Blackburn E H
Altering specific telomerase RNA template residues affects active site function.
Genes & development 1995;9(18):2214-26.
1995: McEachern M J; Blackburn E H
Runaway telomere elongation caused by telomerase RNA gene mutations.
Nature 1995;376(6539):403-9.
1995: Cohn M; Blackburn E H
Telomerase in yeast.
Science (New York, N.Y.) 1995;269(5222):396-400.
1995: Pan W J; Gallagher R C; Blackburn E H
Replication of an rRNA gene origin plasmid in the Tetrahymena thermophila macronucleus is prevented by transcription through the origin from an RNA polymerase I promoter.
Molecular and cellular biology 1995;15(6):3372-81.
1995: Pan W J; Blackburn E H
Tandem repeats of the 5' non-transcribed spacer of Tetrahymena rDNA function as high copy number autonomous replicons in the macronucleus but do not prevent rRNA gene dosage regulation.
Nucleic acids research 1995;23(9):1561-9.
1995: Kirk K E; Blackburn E H
An unusual sequence arrangement in the telomeres of the germ-line micronucleus in Tetrahymena thermophila.
Genes & development 1995;9(1):59-71.
1995: Romero D P; Blackburn E H
Circular rDNA replicons persist in Tetrahymena thermophila transformants synthesizing GGGGTC telomeric repeats.
The Journal of eukaryotic microbiology 1995;42(1):32-43.
1994: Bhattacharyya A; Blackburn E H
Architecture of telomerase RNA.
The EMBO journal 1994;13(23):5721-31.
1994: Blackburn E H
Telomeres: no end in sight.
Cell 1994;77(5):621-3.
1994: Kapler G M; Orias E; Blackburn E H
Tetrahymena thermophila mutants defective in the developmentally programmed maturation and maintenance of the rDNA minichromosome.
Genetics 1994;137(2):455-66.
1994: McEachern M J; Blackburn E H
A conserved sequence motif within the exceptionally diverse telomeric sequences of budding yeasts.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3453-7.
1994: Strahl C; Blackburn E H
The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena.
Nucleic acids research 1994;22(6):893-900.
1994: Gilley D; Blackburn E H
Lack of telomere shortening during senescence in Paramecium.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1955-8.
1994: Kapler G M; Blackburn E H
A weak germ-line excision mutation blocks developmentally controlled amplification of the rDNA minichromosome of Tetrahymena thermophila.
Genes & development 1994;8(1):84-95.
1994: Shippen D E; Blackburn E H; Price C M
DNA bound by the Oxytricha telomere protein is accessible to telomerase and other DNA polymerases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):405-9.
1993: Lee M S; Blackburn E H
Sequence-specific DNA primer effects on telomerase polymerization activity.
Molecular and cellular biology 1993;13(10):6586-99.
1993: Lundblad V; Blackburn E H
An alternative pathway for yeast telomere maintenance rescues est1- senescence.
Cell 1993;73(2):347-60.
1993: Lee M S; Gallagher R C; Bradley J; Blackburn E H
In vivo and in vitro studies of telomeres and telomerase.
Cold Spring Harbor symposia on quantitative biology 1993;58():707-18.
1992: Blackburn E H
Telomerases.
Annual review of biochemistry 1992;61():113-29.
1991: Yu G L; Blackburn E H
Developmentally programmed healing of chromosomes by telomerase in Tetrahymena.
Cell 1991;67(4):823-32.
1991: Romero D P; Blackburn E H
A conserved secondary structure for telomerase RNA.
Cell 1991;67(2):343-53.
1991: Blackburn E H
Telomeres.
Trends in biochemical sciences 1991;16(10):378-81.
1991: Wyman C; Blackburn E H
Tel-1 transposon-like elements of Tetrahymena thermophila are associated with micronuclear genome rearrangements.
Genetics 1991;129(1):57-67.
1991: Blackburn E H
Structure and function of telomeres.
Nature 1991;350(6319):569-73.
1990: Blackburn E H
Telomeres and their synthesis.
Science (New York, N.Y.) 1990;249(4968):489-90.
1990: Blackburn E H
RNA editing. Copy editing--what's the U's?
Nature 1990;346(6285):609-10.
1990: Yu G L; Blackburn E H
Amplification of tandemly repeated origin control sequences confers a replication advantage on rDNA replicons in Tetrahymena thermophila.
Molecular and cellular biology 1990;10(5):2070-80.
1990: Blackburn E H
Telomeres: structure and synthesis.
The Journal of biological chemistry 1990;265(11):5919-21.
1990: Yu G L; Bradley J D; Attardi L D; Blackburn E H
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs.
Nature 1990;344(6262):126-32.
1990: Lundblad V; Blackburn E H
RNA-dependent polymerase motifs in EST1: tentative identification of a protein component of an essential yeast telomerase.
Cell 1990;60(4):529-30.
1990: Shippen-Lentz D; Blackburn E H
Functional evidence for an RNA template in telomerase.
Science (New York, N.Y.) 1990;247(4942):546-52.
1990: Blackburn E H
Cell biology: telomeres sans frontières.
Nature 1990;343(6254):122.
1990: Blackburn E H
Telomeres and their synthesis.
Harvey lectures 1990;86():1-18.
1989: Yu G L; Blackburn E H
Transformation of Tetrahymena thermophila with a mutated circular ribosomal DNA plasmid vector.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8487-91.
1989: Robinson E K; Cohen P D; Blackburn E H
A novel DNA deletion-ligation reaction catalyzed in vitro by a developmentally controlled activity from Tetrahymena cells.
Cell 1989;58(5):887-900.
1989: Phan H L; Forney J; Blackburn E H
Analysis of Paramecium macronuclear DNA using pulsed field gel electrophoresis.
The Journal of protozoology 1989;36(4):402-8.
1989: Shippen-Lentz D; Blackburn E H
Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers.
Molecular and cellular biology 1989;9(6):2761-4.
1989: Shampay J; Blackburn E H
Tetrahymena micronuclear sequences that function as telomeres in yeast.
Nucleic acids research 1989;17(8):3247-60.
1989: Yaeger P C; Orias E; Shaiu W L; Larson D D; Blackburn E H
The replication advantage of a free linear rRNA gene is restored by somatic recombination in Tetrahymena thermophila.
Molecular and cellular biology 1989;9(2):452-60.
1989: Henderson E R; Blackburn E H
An overhanging 3' terminus is a conserved feature of telomeres.
Molecular and cellular biology 1989;9(1):345-8.
1989: Greider C W; Blackburn E H
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis.
Nature 1989;337(6205):331-7.
1989: Blackburn E H; Greider C W; Henderson E; Lee M S; Shampay J; Shippen-Lentz D
Recognition and elongation of telomeres by telomerase.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;31(2):553-60.
1988: Orias E; Larson D; Hu Y F; Yu G L; Karttunen J; Løvlie A; Haller B; Blackburn E H
Replacement of the macronuclear ribosomal RNA genes of a mutant Tetrahymena using electroporation.
Gene 1988;70(2):295-301.
1988: Yu G L; Hasson M; Blackburn E H
Circular ribosomal DNA plasmids transform Tetrahymena thermophila by homologous recombination with endogenous macronuclear ribosomal DNA.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(14):5151-5.
1988: Spangler E A; Ryan T; Blackburn E H
Developmentally regulated telomere addition in Tetrahymena thermophila.
Nucleic acids research 1988;16(12):5569-85.
1988: Forney J D; Blackburn E H
Developmentally controlled telomere addition in wild-type and mutant paramecia.
Molecular and cellular biology 1988;8(1):251-8.
1988: Shampay J; Blackburn E H
Generation of telomere-length heterogeneity in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):534-8.
1987: Henderson E; Hardin C C; Walk S K; Tinoco I; Blackburn E H
Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs.
Cell 1987;51(6):899-908.
1987: Greider C W; Blackburn E H
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity.
Cell 1987;51(6):887-98.
1987: Forney J; Henderson E R; Blackburn E H
Identification of the telomeric sequence of the acellular slime molds Didymium iridis and Physarum polycephalum.
Nucleic acids research 1987;15(22):9143-52.
1987: Larson D D; Spangler E A; Blackburn E H
Dynamics of telomere length variation in Tetrahymena thermophila.
Cell 1987;50(3):477-83.
1986: Larson D D; Blackburn E H; Yaeger P C; Orias E
Control of rDNA replication in Tetrahymena involves a cis-acting upstream repeat of a promoter element.
Cell 1986;47(2):229-40.
1986: Challoner P B; Blackburn E H
Conservation of sequences adjacent to the telomeric C4A2 repeats of ciliate macronuclear ribosomal RNA gene molecules.
Nucleic acids research 1986;14(15):6299-311.
1986: Budarf M L; Blackburn E H
Chromatin structure of the telomeric region and 3'-nontranscribed spacer of Tetrahymena ribosomal RNA genes.
The Journal of biological chemistry 1986;261(1):363-9.
1986: Blackburn E H; Karrer K M
Genomic reorganization in ciliated protozoans.
Annual review of genetics 1986;20():501-21.
1985: Greider C W; Blackburn E H
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
Cell 1985;43(2 Pt 1):405-13.
1985: Cherry J M; Blackburn E H
The internally located telomeric sequences in the germ-line chromosomes of Tetrahymena are at the ends of transposon-like elements.
Cell 1985;43(3 Pt 2):747-58.
1985: Howard E A; Blackburn E H
Reproducible and variable genomic rearrangements occur in the developing somatic nucleus of the ciliate Tetrahymena thermophila.
Molecular and cellular biology 1985;5(8):2039-50.
1985: Spangler E A; Blackburn E H
The nucleotide sequence of the 17S ribosomal RNA gene of Tetrahymena thermophila and the identification of point mutations resulting in resistance to the antibiotics paromomycin and hygromycin.
The Journal of biological chemistry 1985;260(10):6334-40.
1985: Bruns P J; Katzen A L; Martin L; Blackburn E H
A drug-resistant mutation in the ribosomal DNA of Tetrahymena.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):2844-6.
1985: Challoner P B; Amin A A; Pearlman R E; Blackburn E H
Conserved arrangements of repeated DNA sequences in nontranscribed spacers of ciliate ribosomal RNA genes: evidence for molecular coevolution.
Nucleic acids research 1985;13(7):2661-80.
1984: Shampay J; Szostak J W; Blackburn E H
DNA sequences of telomeres maintained in yeast.
Nature 1984;310(5973):154-7.
1984: Blackburn E H
Telomeres: do the ends justify the means?
Cell 1984;37(1):7-8.
1984: Blackburn E H; Challoner P B
Identification of a telomeric DNA sequence in Trypanosoma brucei.
Cell 1984;36(2):447-57.
1984: Blackburn E H
The molecular structure of centromeres and telomeres.
Annual review of biochemistry 1984;53():163-94.
1983: Blackburn E H; Pan W C; Johnson C C
Methylation of ribosomal RNA genes in the macronucleus of Tetrahymena thermophila.
Nucleic acids research 1983;11(15):5131-45.
1983: Blackburn E H; Budarf M L; Challoner P B; Cherry J M; Howard E A; Katzen A L; Pan W C; Ryan T
DNA termini in ciliate macronuclei.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 2():1195-207.
1982: Szostak J W; Blackburn E H
Cloning yeast telomeres on linear plasmid vectors.
Cell 1982;29(1):245-55.
1982: Pan W C; Orias E; Flacks M; Blackburn E H
Allele-specific, selective amplification of a ribosomal RNA gene in Tetrahymena thermophila.
Cell 1982;28(3):595-604.
1981: Katzen A L; Cann G M; Blackburn E H
Sequence-specific fragmentation of macronuclear DNA in a holotrichous ciliate.
Cell 1981;24(2):313-20.
1981: Blackburn E H; Chiou S S
Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2263-7.
1981: Pan W C; Blackburn E H
Single extrachromosomal ribosomal RNA gene copies are synthesized during amplification of the rDNA in Tetrahymena.
Cell 1981;23(2):459-66.
1978: Blackburn E H; Gall J G
A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena.
Journal of molecular biology 1978;120(1):33-53.
1976: Air G M; Blackburn E H; Coulson A R; Galibert F; Sanger F; Sedat J W; Ziff E B
Gene F of bacteriophage phiX174. Correlation of nucleotide sequences from the DNA and amino acid sequences from the gene product.
Journal of molecular biology 1976;107(4):445-58.
1976: Blackburn E H
Transcription and sequence analysis of a fragment of bacteriophage phiX174 DNA.
Journal of molecular biology 1976;107(4):417-31.
1975: Air G M; Blackburn E H; Sanger F; Coulson A R
The nucleotide and amino acid sequences of the N (5') terminal region of gene G of bacteriophage phiphiX 174.
Journal of molecular biology 1975;96(4):703-19.
1975: Blackburn E H
Transcription by Escherichia coli RNA polymerase of a single-stranded fragment by bacteriophage phiX174 DNA 48 residues in length.
Journal of molecular biology 1975;93(3):367-74.
1972: Blackburn E H; Hird F J; Jones I K
Metabolism of glutamine and ammonia in rat liver: the effects of N-acetylglutamate and phosphate.
Archives of biochemistry and biophysics 1972;152(1):265-71.
1972: Blackburn E H; Hird F J
Metabolism of glutamine and glutamate by rat liver mitochondria.
Archives of biochemistry and biophysics 1972;152(1):258-64.
1972: Davidson B E; Blackburn E H; Dopheide T A
Chorismate mutase-prephenate dehydratase from Escherichia coli K-12. I. Purification, molecular weight, and amino acid composition.
The Journal of biological chemistry 1972;247(14):4441-6.
1967: Blackburn E C
Fat absorption studies using triolein I-131 and Oleic Acid I-125 simultaneously.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1967;8(5):356.

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