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Jan Schepens

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Chemicals & Drugs

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Mouse

Anatomy

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Publications

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Yvet E Noordman; Eveline D Augustus; Jan Schepens; Renato G S Chirivi; Pablo Ríos; Rafael Pulido; Wiljan Hendriks
Multimerisation of receptor-type protein tyrosine phosphatases PTPBR7 and PTP-SL attenuates enzymatic activity.
Céline Tárrega; Pablo Ríos; Rocío Cejudo-Marín; Carmen Blanco-Aparicio; Lieke van den Berk; Jan Schepens; Wiljan Hendriks; Lydia Tabernero; Rafael Pulido
ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1.
Renato G S Chirivi; Gönül Dilaver; Rinske van de Vorstenbosch; Bas Wanschers; Jan Schepens; Huib Croes; Jack Fransen; Wiljan Hendriks
Characterization of multiple transcripts and isoforms derived from the mouse protein tyrosine phosphatase gene Ptprr.

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All Publications

2008: Yvet E Noordman; Eveline D Augustus; Jan Schepens; Renato G S Chirivi; Pablo Ríos; Rafael Pulido; Wiljan Hendriks
Multimerisation of receptor-type protein tyrosine phosphatases PTPBR7 and PTP-SL attenuates enzymatic activity.
Biochimica et biophysica acta 2008;1783(2):275-86.
2005: Céline Tárrega; Pablo Ríos; Rocío Cejudo-Marín; Carmen Blanco-Aparicio; Lieke van den Berk; Jan Schepens; Wiljan Hendriks; Lydia Tabernero; Rafael Pulido
ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1.
The Journal of biological chemistry 2005;280(45):37885-94.
2004: Renato G S Chirivi; Gönül Dilaver; Rinske van de Vorstenbosch; Bas Wanschers; Jan Schepens; Huib Croes; Jack Fransen; Wiljan Hendriks
Characterization of multiple transcripts and isoforms derived from the mouse protein tyrosine phosphatase gene Ptprr.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(10):919-33.
2003: Marco van Ham; Huib Croes; Jan Schepens; Jack Fransen; Bé Wieringa; Wiljan Hendriks
Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(7):631-44.
2003: Gönül Dilaver; Jan Schepens; Arn van den Maagdenberg; Mietske Wijers; Barry A Pepers; Jack Fransen; Wiljan Hendriks
Colocalisation of the protein tyrosine phosphatases PTP-SL and PTPBR7 with beta4-adaptin in neuronal cells.
Histochemistry and cell biology 2003;119(1):1-13.
2002: Steffen Gross; Christophe Blanchetot; Jan Schepens; Sabrina Albet; Reiner Lammers; Jeroen den Hertog; Wiljan Hendriks
Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity.
The Journal of biological chemistry 2002;277(50):48139-45.
2002: tine walma; Chris A E M Spronk; Marco Tessari; Jan Aelen; Jan Schepens; Wiljan Hendriks; Geerten W Vuister
Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL.
Journal of molecular biology 2002;316(5):1101-10.
1999: Arn van den Maagdenberg; D Bächner; Jan Schepens; W Peters; J A Fransen; Bé Wieringa; Wiljan Hendriks
The mouse Ptprr gene encodes two protein tyrosine phosphatases, PTP-SL and PTPBR7, that display distinct patterns of expression during neural development.
The European journal of neuroscience 1999;11(11):3832-44.
1999: Edwin Cuppen; Mietske Wijers; Jan Schepens; Jack Fransen; Bé Wieringa; Wiljan Hendriks
A FERM domain governs apical confinement of PTP-BL in epithelial cells.
Journal of cell science 1999;112 ( Pt 19)():3299-308.
1999: Arn van den Maagdenberg; Jan Schepens; M T Schepens; Gerard F M Merkx; F Darroudi; Bé Wieringa; Ad Geurts van Kessel; Wiljan Hendriks
Assignment1 of the PTP-SL/PTPBR7 gene (Ptprr/PTPRR) to mouse chromosome region 8A2 by in situ hybridization.
Cytogenetics and cell genetics 1999;84(3-4):243-4.
1998: RQ Schaapveld; Jan Schepens; D Bächner; Jisk J Attema; Bé Wieringa; PH Jap; Wiljan Hendriks
Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.
Mechanisms of development 1998;77(1):59-62.
1998: Arn van den Maagdenberg; Jan Schepens; M T Schepens; Barry A Pepers; Bé Wieringa; A G van Kessel; Wiljan Hendriks
Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in insulin-dependent diabetes mellitus, to mouse chromosome region 12F.
Cytogenetics and cell genetics 1998;82(3-4):153-5.
1997: RQ Schaapveld; Jan Schepens; G W Robinson; Jisk J Attema; Frank Oerlemans; J A Fransen; M Streuli; Bé Wieringa; L Hennighausen; Wiljan Hendriks
Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity.
Developmental biology 1997;188(1):134-46.
1997: Jan Schepens; Edwin Cuppen; Bé Wieringa; Wiljan Hendriks
The neuronal nitric oxide synthase PDZ motif binds to -G(D,E)XV* carboxyterminal sequences.
FEBS letters 1997;409(1):53-6.
1996: Wiljan Hendriks; C Brugman; K H Richter; Candida A E M van Hooijdonk; Jan Schepens; Joost Schalkwijk; Bé Wieringa
Protein-tyrosine phosphatases expressed in mouse epidermal keratinocytes.
The Journal of investigative dermatology 1996;106(5):972-6.
1995: Wiljan Hendriks; Jan Schepens; D Bächner; JP Rijss; Patrick L J M Zeeuwen; U Zechner; H Hameister; Bé Wieringa
Molecular cloning of a mouse epithelial protein-tyrosine phosphatase with similarities to submembranous proteins.
Journal of cellular biochemistry 1995;59(4):418-30.
1995: R Q Schaapveld; Arn van den Maagdenberg; Jan Schepens; D O Weghuis; Ad Geurts van Kessel; Bé Wieringa; Wiljan Hendriks
The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.
Genomics 1995;27(1):124-30.
1995: Wiljan Hendriks; Jan Schepens; C Brugman; Patrick L J M Zeeuwen; Bé Wieringa
A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.
The Biochemical journal 1995;305 ( Pt 2)():499-504.
1994: Wiljan Hendriks; C Brugman; Jan Schepens; Bé Wieringa
Rapid assessment of protein-tyrosine phosphatase expression levels by RT-PCR with degenerate primers.
Molecular biology reports 1994;19(2):105-8.
1992: Jan Schepens; Patrick L J M Zeeuwen; Bé Wieringa; Wiljan Hendriks
Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.
Molecular biology reports 1992;16(4):241-8.
1992: Jan M A van Deursen; Jan Schepens; W Peters; Dies Meijer; Gerard C Grosveld; Wiljan Hendriks; Bé Wieringa
Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice.
Genomics 1992;12(2):340-9.
1991: Jan M A van Deursen; R Lovell-Badge; Frank Oerlemans; Jan Schepens; Bé Wieringa
Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells.
Nucleic acids research 1991;19(10):2637-43.
1990: H J M Smeets; L Bachinski; M Coerwinkel; Jan Schepens; J Hoeijmakers; M van Duin; K H Grzeschik; C A Weber; P de Jong; M J Siciliano
A long-range restriction map of the human chromosome 19q13 region: close physical linkage between CKMM and the ERCC1 and ERCC2 genes.
American journal of human genetics 1990;46(3):492-501.
1989: Edwin C M Mariman; Jan Schepens; Bé Wieringa
Complete nucleotide sequence of the human creatine kinase B gene.
Nucleic acids research 1989;17(15):6385.
1989: H J M Smeets; M Coerwinkel; Jan Schepens; H Brunner; D Schonk; Hans-Hilger Ropers; Bé Wieringa
EcoRI RFLP at 19q13.1 identified by the anonymous DNA sequence p58B18 [D19S32].
Nucleic acids research 1989;17(9):3628.
1989: H J M Smeets; M Coerwinkel; Jan Schepens; H Brunner; D Schonk; Hans-Hilger Ropers; Bé Wieringa
MspI RFLP at 19q12-q13.1 identified by the anonymous DNA sequence p30B18 [D19S31].
Nucleic acids research 1989;17(9):3627.
1989: H J M Smeets; Jan Schepens; M Coerwinkel; H Brunner; D Schonk; Hans-Hilger Ropers; Bé Wieringa
TaqI RFLP at 19q13.1 identified by the anonymous DNA sequence p5B18 [D19S28].
Nucleic acids research 1989;17(8):3325.
1989: H J M Smeets; Jan Schepens; M Coerwinkel; H Brunner; D Schonk; Hans-Hilger Ropers; Bé Wieringa
MspI RFLP at 19q12-q13.1 identified by the anonymous DNA sequence p20B18 [D19S30].
Nucleic acids research 1989;17(8):3323.
1989: D Schonk; M Coerwinkel-Driessen; I van Dalen; Frank Oerlemans; B Smeets; Jan Schepens; T Hulsebos; D Cockburn; Y Boyd; M Davis
Definition of subchromosomal intervals around the myotonic dystrophy gene region at 19q.
Genomics 1989;4(3):384-96.
1989: H Brunner; M Coerwinkel-Driessen; B Smeets; D Schonk; Jan Schepens; Frank Oerlemans; B Hamel; Hans-Hilger Ropers; Bé Wieringa
Definition of subchromosomal intervals around the myotonic dystrophy locus at 19q.
Progress in clinical and biological research 1989;306():107-14.
1988: M Coerwinkel-Driessen; Jan Schepens; P van Zandvoort; BA van Oost; Edwin C M Mariman; Bé Wieringa
NcoI RFLP at the creatine kinase-muscle type gene locus (CKMM, chromosome 19).
Nucleic acids research 1988;16(17):8743.
1988: T Hulsebos; D Schonk; I van Dalen; M Coerwinkel-Driessen; Jan Schepens; Hans-Hilger Ropers; Bé Wieringa
Isolation and characterization of alphoid DNA sequences specific for the pericentric regions of chromosomes 4, 5, 9, and 19.
Cytogenetics and cell genetics 1988;47(3):144-8.
1987: Edwin C M Mariman; Jan Schepens; A Geurts van Kessel; B Wieringa
EcoRI RFLP at the creatine kinase-brain type gene locus (CKBB, chromosome 14).
Nucleic acids research 1987;15(13):5502.
1987: Jan Schepens; T Hulsebos; H J M Smeets; M Coerwinkel; H Brunner; Hans-Hilger Ropers; Bé Wieringa
A locus at 19cen-19q13.2 (D19S15) containing three RFLPs linked to myotonic dystrophy (DM) is recognized by probe pJSB6.
Nucleic acids research 1987;15(7):3193.
1987: Jan Schepens; H J M Smeets; T Hulsebos; H Brunner; Bé Wieringa
Isolation of a polymorphic DNA sequence pJSB11 (D19S16) from the human chromosome 19cen-q13.2 region linked to the myotonic dystrophy (DM) gene.
Nucleic acids research 1987;15(7):3192.
1986: T Hulsebos; Bé Wieringa; R Hochstenbach; D Smeets; Jan Schepens; Frank Oerlemans; J Zimmer; Hans-Hilger Ropers
Toward early diagnosis of myotonic dystrophy: construction and characterization of a somatic cell hybrid with a single human der(19) chromosome.
Cytogenetics and cell genetics 1986;43(1-2):47-56.