FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Gert Scheper

Research Profile

Chemicals & Drugs

Physiology

Disorders

Concepts & Ideas

Phenomena

Phosphorylation

Anatomy

Procedures

DNA Mutational Analysis

Co-author Network

Publications

TOP 3
Laura van Berge; Marjo S van der Knaap; Marie Sissler; Catherine Florentz; Agnès Gaudry; Josta Kevenaar; Emiel Polder; Gert C Scheper
Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways.
Rogerio A de Almeida; Anne Fogli; Marina Gaillard; Odile Boesflug-Tanguy; Gert C Scheper; Graham D Pavitt
A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease.
M E Steenweg; I K Temple; G Uziel; L van Berge; Carola G M van Berkel; S Vojta; S Blaser; Knut Brockmann; L Carr; I F M de Coo; A Feigenbaum; A Kolk; C I P Mendonça; D Peck; Gert C Scheper; Marjo S van der Knaap
Early-onset LBSL: how severe does it get?

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Gert Scheper (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Laura van Berge; Marjo S van der Knaap; Marie Sissler; Catherine Florentz; Agnès Gaudry; Josta Kevenaar; Emiel Polder; Gert C Scheper
Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways.
The Biochemical journal 2013;450(2):345-50.
2013: Rogerio A de Almeida; Anne Fogli; Marina Gaillard; Odile Boesflug-Tanguy; Gert C Scheper; Graham D Pavitt
A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease.
PloS one 2013;8(1):e53958.
2012: M E Steenweg; I K Temple; G Uziel; L van Berge; Carola G M van Berkel; S Vojta; S Blaser; Knut Brockmann; L Carr; I F M de Coo; A Feigenbaum; A Kolk; C I P Mendonça; D Peck; Gert C Scheper; Marjo S van der Knaap
Early-onset LBSL: how severe does it get?
Neuropediatrics 2012;43(6):332-8.
2012: István Valálik; Marjo S van der Knaap; Akos Jobbágy; Zoltán Liptai; Gert C Scheper; András Csókay
Long-term tremor control with bilateral Vim-DBS in vanishing white matter disease.
Parkinsonism & related disorders 2012;18(9):1048-50.
2012: Laura van Berge; Carola G M van Berkel; Marjo S van der Knaap; Stephanie Dooves; Emiel Polder; Gert C Scheper
Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA.
The Biochemical journal 2012;441(3):955-62.
2011: Margreet C Ridder; Gert C Scheper; Ilja Boor; Arjen B Brussaard; Xavier Capdevila-Nortes; Anna Duarri; Raúl Estévez; Johannes C Lodder; Huibert D Mansvelder; Nienke L Postma; Marjo S van der Knaap
Megalencephalic leucoencephalopathy with cysts: defect in chloride currents and cell volume regulation.
Brain : a journal of neurology 2011;134(Pt 11):3342-54.
2011: Hanna Mierzewska; Gert C Scheper; Elzbieta Szczepanik; Marjo S van der Knaap; Monika Bekiesinska-Figatowska; Elzbieta Jurkiewicz
Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation in the first Polish patient.
Brain & development 2011;33(9):713-7.
2010: Marianna Bugiani; Ilja Boor; James M Powers; Gert C Scheper; Marjo S van der Knaap
Leukoencephalopathy with vanishing white matter: a review.
Journal of neuropathology and experimental neurology 2010;69(10):987-96.
2010: Marjo S van der Knaap; Vincent Lai; Wolfgang Köhler; Mustafa A Salih; Maria-José Fonseca; Tim A Benke; Callum Wilson; Parul Jayakar; Marjo-riitta Aine; Lina Dom; Bryan Lynch; Rozalia Kálmánchey; Peter Pietsch; a Errami; Gert C Scheper
Megalencephalic leukoencephalopathy with cysts without MLC1 defect.
Annals of neurology 2010;67(6):834-7.
2010: Gert C Scheper; Carola G M van Berkel; Lilia Leisle; Koen E de Groot; a Errami; Thomas J Jentsch; Marjo S van der Knaap
Analysis of CLCN2 as candidate gene for megalencephalic leukoencephalopathy with subcortical cysts.
Genetic testing and molecular biomarkers 2010;14(2):255-7.
2010: Uluç Yiş; Gert C Scheper; Nedret Uran; Aycan Unalp; Handan Cakmakçi; Semra Hiz-Kurul; Eray Dirik; Marjo S van der Knaap
Two cases with megalencephalic leukoencephalopathy with subcortical cysts and MLC1 mutations in the Turkish population.
The Turkish journal of pediatrics 2010;52(2):179-83.
2008: Anna Duarri; Oscar Teijido; Tania López-Hernández; Gert C Scheper; Herve Barriere; Ilja Boor; Fernando Aguado; Antonio Zorzano; Manuel Palacín; Albert Martínez; Gergely L Lukacs; Marjo S van der Knaap; Virginia Nunes; Raúl Estévez
Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects.
Human molecular genetics 2008;17(23):3728-39.
2008: Stéphane Mathis; Gert C Scheper; Nicole Baumann; Elodie Petit; Roger Gil; Marjo S van der Knaap; J Ph Neau
The ovarioleukodystrophy.
Clinical neurology and neurosurgery 2008;110(10):1035-7.
2008: Lucia Maria da Costa Fontenelle; Gert C Scheper; Lara Brandão; Marjo S van der Knaap
Atypical presentation of vanishing white matter disease.
Arquivos de neuro-psiquiatria 2008;66(3A):549-51.
2008: Sheila S N Wong; David C K Luk; Virginia C N Wong; Gert C Scheper; Marjo S van der Knaap
Vanishing white matter disease: the first reported chinese patient.
Journal of child neurology 2008;23(6):710-4.
2007: Ilja Boor; Machiel Nagtegaal; Wouter Kamphorst; Paul Van Der Valk; Jan C Pronk; Jack van Horssen; Argirios Dinopoulos; Kevin E Bove; Ignacio Pascual-Castroviejo; Francesco Muntoni; Raúl Estévez; Gert C Scheper; Marjo S van der Knaap
MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet.
Acta neuropathologica 2007;114(4):403-10.
2007: Gert C Scheper; Marjo S van der Knaap; Christopher G Proud
Translation matters: protein synthesis defects in inherited disease.
Nature reviews. Genetics 2007;8(9):711-23.
2007: Gert C Scheper; Thom van der Klok; Rob J van Andel; Carola G M van Berkel; Marie Sissler; Joél Smet; Tatjana I Muravina; Sergey V Serkov; Graziella Uziel; Marianna Bugiani; Raphael Schiffmann; Ingeborg Krägeloh-Mann; Jan A M Smeitink; Catherine Florentz; Rudy Van Coster; Jan C Pronk; Marjo S van der Knaap
Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation.
Nature genetics 2007;39(4):534-9.
2006: Magdalena Kaczorowska; Dariusz Kuczynski; Elzbieta Jurkiewicz; Gert C Scheper; Marjo S van der Knaap; Sergiusz Jozwiak
Acute fright induces onset of symptoms in vanishing white matter disease-case report.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2006;10(4):192-3.
2006: Barbara van Kollenburg; Jantine van Dijk; James Y Garbern; Adri A M Thomas; Gert C Scheper; James M Powers; Marjo S van der Knaap
Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease.
Journal of neuropathology and experimental neurology 2006;65(7):707-15.
2006: P K Ilja Boor; Koen de Groot; Vlatka Mejaski-Bosnjak; Christiana Brenner; Marjo S van der Knaap; Gert C Scheper; Jan C Pronk
Megalencephalic leukoencephalopathy with subcortical cysts: an update and extended mutation analysis of MLC1.
Human mutation 2006;27(6):505-12.
2006: Marjo S van der Knaap; Jan C Pronk; Gert C Scheper
Vanishing white matter disease.
Lancet neurology 2006;5(5):413-23.
2006: Marjo S van der Knaap; Gert C Scheper
Non-eIF2B-related cystic leukoencephalopathy of unknown origin.
Annals of neurology 2006;59(4):724.
2006: Gert C Scheper; Christopher G Proud; Marjo S van der Knaap
Defective translation initiation causes vanishing of cerebral white matter.
Trends in molecular medicine 2006;12(4):159-66.
2006: Barbara van Kollenburg; Adri A M Thomas; Gerre Vermeulen; Gesina A M Bertrand; Carola G M van Berkel; Jan C Pronk; Christopher G Proud; Marjo S van der Knaap; Gert C Scheper
Regulation of protein synthesis in lymphoblasts from vanishing white matter patients.
Neurobiology of disease 2006;21(3):496-504.
2006: Hanna Mierzewska; Marjo S van der Knaap; Gert C Scheper; Elzbieta Jurkiewicz; Bogna Schmidt-Sidor; Krystyna Szymańska
Leukoencephalopathy with vanishing white matter due to homozygous EIF2B2 gene mutation. First Polish cases.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2006;44(2):144-8.
2006: Jan C Pronk; Barbara van Kollenburg; Gert C Scheper; Marjo S van der Knaap
Vanishing white matter disease: a review with focus on its genetics.
Mental retardation and developmental disabilities research reviews 2006;12(2):123-8.
2005: Elzbieta Jurkiewicz; Hanna Mierzewska; Monika Bekiesińska-Figatowska; Iwona Pakua-Kościesza; Tomasz Kmieć; Gert C Scheper; Marjo S van der Knaap; Ewa Pronicka
MRI of a family with leukoencephalypathy with vanishing white matter.
Pediatric radiology 2005;35(10):1027-30.
2005: J Patrick van der Voorn; Barbara van Kollenburg; Gesina Bertrand; Keith Van Haren; Gert C Scheper; James M Powers; Marjo S van der Knaap
The unfolded protein response in vanishing white matter disease.
Journal of neuropathology and experimental neurology 2005;64(9):770-5.
2005: P K Ilja Boor; Koen de Groot; Quinten Waisfisz; Wouter Kamphorst; Cees B M Oudejans; James M Powers; Jan C Pronk; Gert C Scheper; Marjo S van der Knaap
MLC1: a novel protein in distal astroglial processes.
Journal of neuropathology and experimental neurology 2005;64(5):412-9.
2005: Gerre Vermeulen; Rainer Seidl; Saadet Mercimek-Mahmutoglu; Jan J Rotteveel; Gert C Scheper; Marjo S van der Knaap
Fright is a provoking factor in vanishing white matter disease.
Annals of neurology 2005;57(4):560-3.
2005: Josep L Parra-Palau; Gert C Scheper; Daniel E Harper; Christopher G Proud
The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo.
The Biochemical journal 2005;385(Pt 3):695-702.
2003: Josep-Lluis Parra-Palau; Gert C Scheper; Mary L Wilson; Christopher G Proud
Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling.
The Journal of biological chemistry 2003;278(45):44197-204.
2003: Marjo S van der Knaap; Carola G M van Berkel; Jochen Herms; Rudy Van Coster; Martina Baethmann; Sakkubai Naidu; Eugen Boltshauser; Michèl A A P Willemsen; Barbara Plecko; Georg F Hoffmann; Christopher G Proud; Gert C Scheper; Jan C Pronk
eIF2B-related disorders: antenatal onset and involvement of multiple organs.
American journal of human genetics 2003;73(5):1199-207.
2003: Gert C Scheper; Josep Lluis Parra; Mary Wilson; Barbara van Kollenburg; Alfred C O Vertegaal; Ze-Guang Han; Christopher G Proud
The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization.
Molecular and cellular biology 2003;23(16):5692-705.
2002: Miranda Kleijn; Gert C Scheper; Mary L Wilson; Andrew R Tee; Christopher G Proud
Localisation and regulation of the eIF4E-binding protein 4E-BP3.
FEBS letters 2002;532(3):319-23.
2002: Gert C Scheper; Christopher G Proud
Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?
European journal of biochemistry / FEBS 2002;269(22):5350-9.
2002: Gert C Scheper; Barbara van Kollenburg; Jianzhong HU; Yunjing Luo; Dixie J Goss; Christopher G Proud
Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.
The Journal of biological chemistry 2002;277(5):3303-9.
2001: Gert C Scheper; Nick A Morrice; Miranda Kleijn; Christopher G Proud
The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells.
Molecular and cellular biology 2001;21(3):743-54.
2001: Gert C Scheper; Roeland Van Wijk; A M Thomas
Regulation of the activity of eukaryotic initiation factors in stressed cells.
Progress in molecular and subcellular biology 2001;27():40-56.
1998: Gert C Scheper; Adri A M Thomas; Roeland Van Wijk
Inactivation of eukaryotic initiation factor 2B in vitro by heat shock.
The Biochemical journal 1998;334 ( Pt 2)():463-7.
1998: Miranda Kleijn; Gert C Scheper; Harry O Voorma; Adri A M Thomas
Regulation of translation initiation factors by signal transduction.
European journal of biochemistry / FEBS 1998;253(3):531-44.
1998: Miranda Kleijn; G I Welsh; Gert C Scheper; Harry O Voorma; Christopher G Proud; Adri A M Thomas
Nerve and epidermal growth factor induce protein synthesis and eIF2B activation in PC12 cells.
The Journal of biological chemistry 1998;273(10):5536-41.
1997: Gert C Scheper; Jacqueline Mulder; Miranda Kleijn; Harry O Voorma; Adri A M Thomas; Roeland Van Wijk
Inactivation of eIF2B and phosphorylation of PHAS-I in heat-shocked rat hepatoma cells.
The Journal of biological chemistry 1997;272(43):26850-6.
1997: Gert C Scheper; R G Vries; M Broere; Magda Usmany; Harry O Voorma; Just M Vlak; Adri A M Thomas
Translational properties of the untranslated regions of the p10 messenger RNA of Autographa californica multicapsid nucleopolyhedrovirus.
The Journal of general virology 1997;78 ( Pt 3)():687-96.
1994: Gert C Scheper; Harry O Voorma; Adri A M Thomas
Basepairing with 18S ribosomal RNA in internal initiation of translation.
FEBS letters 1994;352(3):271-5.
1994: Gert C Scheper; Harry O Voorma; Adri A M Thomas
Binding of eukaryotic initiation factor-2 and trans-acting factors to the 5' untranslated region of encephalomyocarditis virus RNA.
Biochimie 1994;76(8):801-9.
1992: Adri A M Thomas; Gert C Scheper; Miranda Kleijn; M De Boer; Harry O Voorma
Dependence of the adenovirus tripartite leader on the p220 subunit of eukaryotic initiation factor 4F during in vitro translation. Effect of p220 cleavage by foot-and-mouth-disease-virus L-protease on in vitro translation.
European journal of biochemistry / FEBS 1992;207(2):471-7.
1992: Gert C Scheper; Harry O Voorma; Adri A M Thomas
Eukaryotic initiation factors-4E and -4F stimulate 5' cap-dependent as well as internal initiation of protein synthesis.
The Journal of biological chemistry 1992;267(11):7269-74.
1992: Adri A M Thomas; Gert C Scheper; Harry O Voorma
Hypothesis: is eukaryotic initiation factor 2 the scanning factor?
The New biologist 1992;4(4):404-7.
1991: Gert C Scheper; Adri A M Thomas; Harry O Voorma
The 5' untranslated region of encephalomyocarditis virus contains a sequence for very efficient binding of eukaryotic initiation factor eIF-2/2B.
Biochimica et biophysica acta 1991;1089(2):220-6.
1990: P Oudshoorn; A Thomas; Gert C Scheper; Harry O Voorma
An initiation signal in the 5' untranslated leader sequence of encephalomyocarditis virus RNA.
Biochimica et biophysica acta 1990;1050(1-3):124-8.