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Gerrit Scherphof

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Piotr S Kowalski; Niek G J Leus; Marcel H J Ruiters; Gerrit L Scherphof; Jan A A M Kamps; Grietje Molema
Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts.
Alida H Weeke-Klimp; Martin Bartsch; Henriëtte W M Morselt; Ingrid Van Veen-Hof; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Targeting of stabilized plasmid lipid particles to hepatocytes in vivo by means of coupled lactoferrin.
Joanna E Adrian; Jan A A M Kamps; Gerrit L Scherphof; Dirk K F Meijer; Anne-miek Van Loenen-Weemaes; Catharina Reker-Smit; Peter Terpstra; Klaas Poelstra
A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats.

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2011: Piotr S Kowalski; Niek G J Leus; Marcel H J Ruiters; Gerrit L Scherphof; Jan A A M Kamps; Grietje Molema
Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts.
IUBMB life 2011;63(8):648-58.
2007: Alida H Weeke-Klimp; Martin Bartsch; Henriëtte W M Morselt; Ingrid Van Veen-Hof; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Targeting of stabilized plasmid lipid particles to hepatocytes in vivo by means of coupled lactoferrin.
Journal of drug targeting 2007;15(9):585-94.
2007: Joanna E Adrian; Jan A A M Kamps; Gerrit L Scherphof; Dirk K F Meijer; Anne-miek Van Loenen-Weemaes; Catharina Reker-Smit; Peter Terpstra; Klaas Poelstra
A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats.
Biochimica et biophysica acta 2007;1768(6):1430-9.
2007: Joanna E Adrian; Klaas Poelstra; Gerrit L Scherphof; Dirk K F Meijer; Anne-miek Van Loenen-Weemaes; Catharina Reker-Smit; Henriëtte W M Morselt; Peter Zwiers; Jan A A M Kamps
Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
The Journal of pharmacology and experimental therapeutics 2007;321(2):536-43.
2007: Joanna E Adrian; Jan A A M Kamps; Klaas Poelstra; Gerrit L Scherphof; Dirk K F Meijer; Yasufumi Kaneda
Delivery of viral vectors to hepatic stellate cells in fibrotic livers using HVJ envelopes fused with targeted liposomes.
Journal of drug targeting 2007;15(1):75-82.
2006: Joanna E Adrian; Klaas Poelstra; Gerrit L Scherphof; Grietje Molema; Dirk K F Meijer; Catharina Reker-Smit; Henriëtte W M Morselt; Jan A A M Kamps
Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems.
Journal of hepatology 2006;44(3):560-7.
2005: Xuedong Yan; Folkert Kuipers; Louis M Havekes; Rick Havinga; Bert Dontje; Klaas Poelstra; Gerrit L Scherphof; Jan A A M Kamps
The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse.
Biochemical and biophysical research communications 2005;328(1):57-62.
2005: Martin Bartsch; Alida H Weeke-Klimp; Henriëtte W M Morselt; Andrea Kimpfler; Sigridur A Asgeirsdóttir; Rolf Schubert; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells.
Molecular pharmacology 2005;67(3):883-90.
2005: C Rothkopf; Alfred Fahr; Gert Fricker; Gerrit L Scherphof; Jan A A M Kamps
Uptake of phosphatidylserine-containing liposomes by liver sinusoidal endothelial cells in the serum-free perfused rat liver.
Biochimica et biophysica acta 2005;1668(1):10-6.
2005: Xuedong Yan; Gerrit L Scherphof; Jan A A M Kamps
Liposome opsonization.
Journal of liposome research 2005;15(1-2):109-39.
2005: Martin Bartsch; Alida H Weeke-Klimp; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Cell-specific targeting of lipid-based carriers for ODN and DNA.
Journal of liposome research 2005;15(1-2):59-92.
2004: X Yan; Klaas Poelstra; Gerrit L Scherphof; Jan A A M Kamps
A role for scavenger receptor B-I in selective transfer of rhodamine-PE from liposomes to cells.
Biochemical and biophysical research communications 2004;325(3):908-14.
2004: X Yan; Henriëtte W M Morselt; Gerrit L Scherphof; Klaas Poelstra; Jan A A M Kamps
The role of beta2-glycoprotein I in liposome-hepatocyte interaction.
Biochimica et biophysica acta 2004;1667(2):208-14.
2004: Martin Bartsch; Alida H Weeke-Klimp; Evelien P D Hoenselaar; Marc Stuart; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Stabilized lipid coated lipoplexes for the delivery of antisense oligonucleotides to liver endothelial cells in vitro and in vivo.
Journal of drug targeting 2004;12(9-10):613-21.
2004: Jan A A M Kamps; Gerrit L Scherphof
Biodistribution and uptake of liposomes in vivo.
Methods in enzymology 2004;387():257-66.
2003: Gerben A Koning; Henriëtte W M Morselt; Arko Gorter; Theresa M Allen; Samuel Zalipsky; Gerrit L Scherphof; Jan A A M Kamps
Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison.
Pharmaceutical research 2003;20(8):1249-57.
2003: Gerd Bendas; Ulrich Rothe; Gerrit L Scherphof; Jan A A M Kamps
The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stabilized immunoliposomes.
Biochimica et biophysica acta 2003;1609(1):63-70.
2002: AH Klimp; E G E de Vries; Gerrit L Scherphof; Toos Daemen
A potential role of macrophage activation in the treatment of cancer.
Critical reviews in oncology/hematology 2002;44(2):143-61.
2002: Martin Bartsch; Alida H Weeke-Klimp; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Massive and selective delivery of lipid-coated cationic lipoplexes of oligonucleotides targeted in vivo to hepatic endothelial cells.
Pharmaceutical research 2002;19(5):676-80.
2002: Gerben A Koning; Jan A A M Kamps; Gerrit L Scherphof
Interference of macrophages with immunotargeting of liposomes.
Journal of liposome research 2002;12(1-2):107-19.
2002: Gerben A Koning; Jan A A M Kamps; Gerrit L Scherphof
Efficient intracellular delivery of 5-fluorodeoxyuridine into colon cancer cells by targeted immunoliposomes.
Cancer detection and prevention 2002;26(4):299-307.
2002: Ewa Zant-Przeworska; Jan A A M Kamps; Anton J M Roks; Wiek H Gilst; Gerrit L Scherphof
Development of liposomal gene targeting for therapeutic intervention or prevention of restenosis.
Cellular & molecular biology letters 2002;7(2):268-9.
2002: Gerrit L Scherphof; Gerben A Koning; Martin Bartsch; Xuedong Yan; Jan A A M Kamps
Targeting liposomes and lipoplexes to cells in the liver.
Cellular & molecular biology letters 2002;7(2):251-4.
2001: Gerben A Koning; Henriëtte W M Morselt; Arko Gorter; Theresa M Allen; Samuel Zalipsky; Jan A A M Kamps; Gerrit L Scherphof
Pharmacokinetics of differently designed immunoliposome formulations in rats with or without hepatic colon cancer metastases.
Pharmaceutical research 2001;18(9):1291-8.
2001: Gerrit L Scherphof; Jan A A M Kamps
The role of hepatocytes in the clearance of liposomes from the blood circulation.
Progress in lipid research 2001;40(3):149-66.
2001: AH Klimp; E van der Vaart; P O Lansink; Sebo Withoff; Elisabeth G E de Vries; Gerrit L Scherphof; Jan Wilschut; Toos Daemen
Activation of peritoneal cells upon in vivo transfection with a recombinant alphavirus expressing GM-CSF.
Gene therapy 2001;8(4):300-7.
2001: Gerben A Koning; H W Morselt; J A Kamps; Gerrit L Scherphof
Uptake and intracellular processing of PEG-liposomes and PEG-immunoliposomes by kupffer cells in vitro 1 *.
Journal of liposome research 2001;11(2-3):195-209.
2000: AH Klimp; Elisabeth G E de Vries; Gerrit L Scherphof; Toos Daemen
Chemo-immunotherapy of ovarian cancer in a murine tumour model.
Anticancer research 2000;20(4):2585-92.
2000: Jan A A M Kamps; Gerben A Koning; Maria J Velinova; Henriëtte W M Morselt; M Wilkens; Arko Gorter; J Donga; Gerrit L Scherphof
Uptake of long-circulating immunoliposomes, directed against colon adenocarcinoma cells, by liver metastases of colon cancer.
Journal of drug targeting 2000;8(4):235-45.
1999: K P de Jong; M Brinker; ML van Veen; Toos Daemen; Gerrit L Scherphof; Maarten J H Slooff
[3H]thymidine incorporation into whole liver as an alternative to [3H]thymidine incorporation into DNA as a parameter of cell proliferation in regenerating liver tissue in rats.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1999;21(6):498-504.
1999: Gerben A Koning; Henriëtte W M Morselt; Maria J Velinova; J Donga; Arko Gorter; Theresa M Allen; Samuel Zalipsky; Jan A A M Kamps; Gerrit L Scherphof
Selective transfer of a lipophilic prodrug of 5-fluorodeoxyuridine from immunoliposomes to colon cancer cells.
Biochimica et biophysica acta 1999;1420(1-2):153-67.
1999: Gerben A Koning; Arko Gorter; Gerrit L Scherphof; Jan A A M Kamps
Antiproliferative effect of immunoliposomes containing 5-fluorodeoxyuridine-dipalmitate on colon cancer cells.
British journal of cancer 1999;80(11):1718-25.
1999: Eder Lilia Romero; Maria Jose Morilla; Joke Regts; Gerben A Koning; Gerrit L Scherphof
On the mechanism of hepatic transendothelial passage of large liposomes.
FEBS letters 1999;448(1):193-6.
1999: Jan A A M Kamps; Henriëtte W M Morselt; Gerrit L Scherphof
Uptake of liposomes containing phosphatidylserine by liver cells in vivo and by sinusoidal liver cells in primary culture: in vivo-in vitro differences.
Biochemical and biophysical research communications 1999;256(1):57-62.
1999: AH Klimp; Joke Regts; Gerrit L Scherphof; Elisabeth G E de Vries; Toos Daemen
Effect of intraperitoneally administered recombinant murine granulocyte-macrophage colony-stimulating factor (rmGM-CSF) on the cytotoxic potential of murine peritoneal cells.
British journal of cancer 1999;79(1):89-94.
1998: M van Borssum Waalkes; H Goris; B H Dontje; Reto Schwendener; Gerrit L Scherphof; willem nijhof
Toxicity of liposomal 3'-5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine in mice.
Anti-cancer drug design 1998;13(4):291-305.
1998: Christien Oussoren; Maria J Velinova; Gerrit L Scherphof; Johannes van der Want; Nico van Rooijen; Gert Storm
Lymphatic uptake and biodistribution of liposomes after subcutaneous injection . IV. Fate of liposomes in regional lymph nodes.
Biochimica et biophysica acta 1998;1370(2):259-72.
1998: K P de Jong; M A Brouwers; ML van Veen; M Brinker; Elisabeth G E de Vries; Toos Daemen; Gerrit L Scherphof; Maarten J H Slooff
Serum obtained from rats after partial hepatectomy enhances growth of cultured colon carcinoma cells.
Invasion & metastasis 1998;18(3):155-64.
1997: Jan A A M Kamps; Henriëtte W M Morselt; P J Swart; Dirk K F Meijer; Gerrit L Scherphof
Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11681-5.
1997: Toos Daemen; Maria J Velinova; Joke Regts; Marina H de Jager; R Kalicharan; J Donga; Johannes van der Want; Gerrit L Scherphof
Different intrahepatic distribution of phosphatidylglycerol and phosphatidylserine liposomes in the rat.
Hepatology (Baltimore, Md.) 1997;26(2):416-23.
1997: K Shimada; Jan A A M Kamps; Joke Regts; K Ikeda; T Shiozawa; S Hirota; Gerrit L Scherphof
Biodistribution of liposomes containing synthetic galactose-terminated diacylglyceryl-poly(ethyleneglycol)s.
Biochimica et biophysica acta 1997;1326(2):329-41.
1996: Toos Daemen; Joke Regts; Gerrit L Scherphof
Liposomal phosphatidylserine inhibits tumor cytotoxicity of liver macrophages induced by muramyl dipeptide and lipopolysaccharide.
Biochimica et biophysica acta 1996;1285(2):219-28.
1996: Jan A A M Kamps; Pieter J Swart; Henriëtte W M Morselt; R Pauwels; Marie-Pierre de Bethune; E De Clercq; Dirk K F Meijer; Gerrit L Scherphof
Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity.
Biochimica et biophysica acta 1996;1278(2):183-90.
1995: R M Hoedemakers; Henriëtte W M Morselt; Gerrit L Scherphof; Toos Daemen
Heterogeneity in secretory responses of rat liver macrophages of different size.
Liver 1995;15(6):313-9.
1995: K Thomas; A M Nijenhuis; Bert Dontje; Toos Daemen; Gerrit L Scherphof
Antitumor reactivity induced by liposomal MTP-PE in a liver metastasis model of colon cancer in the rat.
Clinical & experimental metastasis 1995;13(5):328-36.
1995: R M Hoedemakers; J E Atmosoerodjo-Briggs; Henriëtte W M Morselt; Toos Daemen; Gerrit L Scherphof; M J Hardonk
Histochemical and electron microscopic characterization of hepatic macrophage subfractions isolated from normal and liposomal muramyl dipeptide treated rats.
Liver 1995;15(3):113-20.
1995: Toos Daemen; G Hofstede; Marian T ten Kate; Irma A J M Bakker-Woudenberg; Gerrit L Scherphof
Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages.
International journal of cancer. Journal international du cancer 1995;61(5):716-21.
1995: C Thomas; A M Nijenhuis; Bert Dontje; Toos Daemen; Gerrit L Scherphof
Tumoricidal response of liver macrophages isolated from rats bearing liver metastases of colon adenocarcinoma.
Journal of leukocyte biology 1995;57(4):617-23.
1995: A Mori; S J Kennel; M van Borssum Waalkes; Gerrit L Scherphof; Leaf Huang
Characterization of organ-specific immunoliposomes for delivery of 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine in a mouse lung-metastasis model.
Cancer chemotherapy and pharmacology 1995;35(6):447-56.
1994: R M Hoedemakers; Henriëtte W M Morselt; Gerrit L Scherphof; Toos Daemen
Secretion pattern of the rat liver macrophage population following activation with liposomal muramyl dipeptide in vivo and in vitro.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;15(4):265-72.
1994: R M Hoedemakers; Gerrit L Scherphof; Toos Daemen
Proliferation of rat liver macrophages in vitro: influence of hemopoietic growth factors.
Hepatology (Baltimore, Md.) 1994;19(3):666-74.
1994: M J Smit; Henkjan J Verkade; Rick Havinga; roel vonk; Gerrit L Scherphof; G In 't Veld; Folkert Kuipers
Dietary fish oil potentiates bile acid-induced cholesterol secretion into bile in rats.
Journal of lipid research 1994;35(2):301-10.
1993: M van Borssum Waalkes; M van Galen; Henriëtte W M Morselt; B Sternberg; Gerrit L Scherphof
In-vitro stability and cytostatic activity of liposomal formulations of 5-fluoro-2'-deoxyuridine and its diacylated derivatives.
Biochimica et biophysica acta 1993;1148(1):161-72.
1993: R M Hoedemakers; P J Vossebeld; Toos Daemen; Gerrit L Scherphof
Functional characteristics of the rat liver macrophage population after a single intravenous injection of liposome-encapsulated muramyl peptides.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;13(4):252-60.
1993: M van Borssum Waalkes; F Kuipers; Rick Havinga; Gerrit L Scherphof
Conversion of liposomal 5-fluoro-2'-deoxyuridine and its dipalmitoyl derivative to bile acid conjugates of alpha-fluoro-beta-alanine and their excretion into rat bile.
Biochimica et biophysica acta 1993;1176(1-2):43-50.
1993: Toos Daemen; Bert Dontje; Joke Regts; Gerrit L Scherphof
Chemoimmunotherapy of murine liver metastases with 5-fluorouracil in combination with liposome-encapsulated muramyl dipeptide.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;13(1):31-5.
1993: C Thomas; A M Nijenhuis; Wim Timens; Peter Kuppen; Toos Daemen; Gerrit L Scherphof
Liver metastasis model of colon cancer in the rat: immunohistochemical characterization.
Invasion & metastasis 1993;13(2):102-12.
1992: M Van Borssum Waalkes; Iduna Fichtner; Bert Dontje; M Lemm; M Becker; Dieter Arndt; Gerrit L Scherphof
In vivo distribution and antitumour activity of liposomal 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine.
Journal of microencapsulation 1992;9(3):335-46.
1992: Toos Daemen; Joke Regts; Henriëtte W M Morselt; Gerrit L Scherphof
The effect of liver macrophages on in vitro cytolytic activity of 5FU and FUdR on colon carcinoma cells: evidence of macrophage activation.
International journal of immunopharmacology 1992;14(5):857-64.
1992: Henkjan J Verkade; K J Zaal; J T Derksen; roel vonk; Dick Hoekstra; Folkert Kuipers; Gerrit L Scherphof
Processing of the phospholipid analogue phosphatidyl(N-sulphorhodamine B sulphonyl)ethanolamine by rat hepatocytes in vitro and in vivo.
The Biochemical journal 1992;284 ( Pt 1)():259-65.
1991: Toos Daemen; A Veninga; Joke Regts; Gerrit L Scherphof
Maintenance of tumoricidal activity and susceptibility to reactivation of subpopulations of rat liver macrophages.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(3):200-6.
1991: Henkjan J Verkade; J T Derksen; A Gerding; Gerrit L Scherphof; roel vonk; Folkert Kuipers
Differential hepatic processing and biliary secretion of head-group and acyl chains of liposomal phosphatidylcholines.
The Biochemical journal 1991;275 ( Pt 1)():139-44.
1990: J Willem; M ter Beest; Gerrit L Scherphof; Dick Hoekstra
A non-exchangeable fluorescent phospholipid analog as a membrane traffic marker of the endocytic pathway.
European journal of cell biology 1990;53(1):173-84.
1990: Toos Daemen; Bert Dontje; A Veninga; Gerrit L Scherphof; W L Oosterhuis
Therapy of murine liver metastases by administration of MDP encapsulated in liposomes.
Selective cancer therapeutics 1990;6(2):63-71.
1990: M Van Borssum Waalkes; Gerrit L Scherphof
Liposome-incorporated 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine as a slow-release anti-tumor drug depot in rat liver macrophages.
Selective cancer therapeutics 1990;6(1):15-22.
1989: G Lázár; M van Galen; Gerrit L Scherphof
Gadolinium chloride-induced shifts in intrahepatic distributions of liposomes.
Biochimica et biophysica acta 1989;1011(2-3):97-101.
1989: Toos Daemen; A Veninga; F H Roerdink; Gerrit L Scherphof
Conditions controlling tumor cytotoxicity of rat liver macrophages mediated by liposomal muramyl dipeptide.
Biochimica et biophysica acta 1989;991(1):145-51.
1989: F H Roerdink; Joke Regts; T Handel; S M Sullivan; J D Baldeschwieler; Gerrit L Scherphof
Effect of cholesterol on the uptake and intracellular degradation of liposomes by liver and spleen; a combined biochemical and gamma-ray perturbed angular correlation study.
Biochimica et biophysica acta 1989;980(2):234-40.
1989: Toos Daemen; A Veninga; J Dijkstra; Gerrit L Scherphof
Differential effects of liposome-incorporation on liver macrophage activating potencies of rough lipopolysaccharide, lipid A, and muramyl dipeptide. Differences in susceptibility to lysosomal enzymes.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(7):2469-74.
1989: Gerrit L Scherphof; H H Spanjer; J T Derksen; G Lázár; F H Roerdink
Targeting of liposomes to liver cells.
Horizons in biochemistry and biophysics 1989;9():281-91.
1989: Toos Daemen; A Veninga; F H Roerdink; Gerrit L Scherphof
Endocytic and tumoricidal heterogeneity of rat liver macrophage populations.
Selective cancer therapeutics 1989;5(4):157-67.
1988: J T Derksen; J D Baldeschwieler; Gerrit L Scherphof
In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9768-72.
1988: J T Derksen; Henriëtte W M Morselt; Gerrit L Scherphof
Uptake and processing of immunoglobulin-coated liposomes by subpopulations of rat liver macrophages.
Biochimica et biophysica acta 1988;971(2):127-36.
1987: Gerrit L Scherphof; Folkert Kuipers; J T Derksen; H H Spanjer; roel vonk
Liposomes in vivo; conversion of liposomal cholesterol to bile salts.
Biochemical Society transactions 1987;15 Suppl():62S-68S.
1987: Folkert Kuipers; J P Derksen; A Gerding; Gerrit L Scherphof; roel vonk
Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid.
Biochimica et biophysica acta 1987;922(2):136-44.
1987: Gerrit L Scherphof; Toos Daemen; H H Spanjer; F H Roerdink
Liposomes in chemo- and immunotherapy of cancer.
Lipids 1987;22(11):891-6.
1987: J T Derksen; Henriëtte W M Morselt; Gerrit L Scherphof
Processing of different liposome markers after in vitro uptake of immunoglobulin-coated liposomes by rat liver macrophages.
Biochimica et biophysica acta 1987;931(1):33-40.
1987: Toon Stegmann; Henriëtte W M Morselt; frank booy; JF van Breemen; Gerrit L Scherphof; Jan Wilschut
Functional reconstitution of influenza virus envelopes.
The EMBO journal 1987;6(9):2651-9.
1987: Gerrit L Scherphof; H H Spanjer; J T Derksen; Folkert Kuipers; roel vonk; Toos Daemen; F H Roerdink
Delivery of liposome-associated drugs to liver cells.
Biochemical Society transactions 1987;15(3):345-8.
1987: J T Derksen; Henriëtte W M Morselt; Dharamdajal Kalicharan; C E Hulstaert; Gerrit L Scherphof
Interaction of immunoglobulin-coupled liposomes with rat liver macrophages in vitro.
Experimental cell research 1987;168(1):105-15.
1986: H H Spanjer; M van Galen; F H Roerdink; Joke Regts; Gerrit L Scherphof
Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition.
Biochimica et biophysica acta 1986;863(2):224-30.
1986: Toos Daemen; A Veninga; F H Roerdink; Gerrit L Scherphof
In vitro activation of rat liver macrophages to tumoricidal activity by free or liposome-encapsulated muramyl dipeptide.
Cancer research 1986;46(9):4330-5.
1986: Toon Stegmann; D Hoekstra; Gerrit L Scherphof; Jan Wilschut
Fusion activity of influenza virus. A comparison between biological and artificial target membrane vesicles.
The Journal of biological chemistry 1986;261(24):10966-9.
1986: Folkert Kuipers; H H Spanjer; Rick Havinga; Gerrit L Scherphof; roel vonk
Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids.
Biochimica et biophysica acta 1986;876(3):559-66.
1985: A J Driessen; Dick Hoekstra; Gerrit L Scherphof; R D Kalicharan; Jan Wilschut
Low pH-induced fusion of liposomes with membrane vesicles derived from Bacillus subtilis.
The Journal of biological chemistry 1985;260(19):10880-7.
1985: H H Spanjer; Theo Van berkel; Gerrit L Scherphof; H J Kempen
The effect of a water-soluble tris-galactoside terminated cholesterol derivative on the in vivo fate of small unilamellar vesicles in rats.
Biochimica et biophysica acta 1985;816(2):396-402.
1985: J Dijkstra; M van Galen; Gerrit L Scherphof
Effects of (dihydro)cytochalasin B, colchicine, monensin and trifluoperazine on uptake and processing of liposomes by Kupffer cells in culture.
Biochimica et biophysica acta 1985;845(1):34-42.
1985: J Dijkstra; M van Galen; D Regts; Gerrit L Scherphof
Uptake and processing of liposomal phospholipids by Kupffer cells in vitro.
European journal of biochemistry / FEBS 1985;148(2):391-7.
1985: J Dijkstra; M van Galen; Gerrit L Scherphof
Influence of liposome charge on the association of liposomes with Kupffer cells in vitro. Effects of divalent cations and competition with latex particles.
Biochimica et biophysica acta 1985;813(2):287-97.
1985: Gerrit L Scherphof; J Dijkstra; H H Spanjer; J T Derksen; F H Roerdink
Uptake and intracellular processing of targeted and nontargeted liposomes by rat Kupffer cells in vivo and in vitro.
Annals of the New York Academy of Sciences 1985;446():368-84.
1984: Gerrit L Scherphof; Henriëtte W M Morselt
On the size-dependent disintegration of small unilamellar phosphatidylcholine vesicles in rat plasma. Evidence of complete loss of vesicle structure.
The Biochemical journal 1984;221(2):423-9.
1984: H H Spanjer; Henriëtte W M Morselt; Gerrit L Scherphof
Lactosylceramide-induced stimulation of liposome uptake by Kupffer cells in vivo.
Biochimica et biophysica acta 1984;774(1):49-55.
1984: J Dijkstra; M Van Galen; Gerrit L Scherphof
Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro.
Biochimica et biophysica acta 1984;804(1):58-67.
1984: F H Roerdink; J Dijkstra; H H Spanjer; Gerrit L Scherphof
Interaction of liposomes with hepatocytes and Kupffer cells in vivo and in vitro.
Biochemical Society transactions 1984;12(2):335-6.
1984: F Roerdink; J Regts; B Van Leeuwen; Gerrit L Scherphof
Intrahepatic uptake and processing of intravenously injected small unilamellar phospholipid vesicles in rats.
Biochimica et biophysica acta 1984;770(2):195-202.
1984: J Dijkstra; W J van Galen; C E Hulstaert; Dharamdajal Kalicharan; F H Roerdink; Gerrit L Scherphof
Interaction of liposomes with Kupffer cells in vitro.
Experimental cell research 1984;150(1):161-76.
1983: P Soriano; J Dijkstra; A Legrand; H Spanjer; D Londos-Gagliardi; F Roerdink; Gerrit L Scherphof; C Nicolau
Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(23):7128-31.
1983: H H Spanjer; Gerrit L Scherphof
Targeting of lactosylceramide-containing liposomes to hepatocytes in vivo.
Biochimica et biophysica acta 1983;734(1):40-7.
1983: H Ellens; Henriëtte W M Morselt; Bert Dontje; Dharamdajal Kalicharan; C E Hulstaert; Gerrit L Scherphof
Effects of liposome dose and the presence of lymphosarcoma cells on blood clearance and tissue distribution of large unilamellar liposomes in mice.
Cancer research 1983;43(6):2927-34.
1982: J Damen; J Regts; Gerrit L Scherphof
Transfer of [14C]phosphatidylcholine between liposomes and human plasma high density lipoprotein. Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay.
Biochimica et biophysica acta 1982;712(3):444-52.
1981: J Damen; J Regts; Gerrit L Scherphof
Transfer and exchange of phospholipid between small unilamellar liposomes and rat plasma high density lipoproteins. Dependence on cholesterol content and phospholipid composition.
Biochimica et biophysica acta 1981;665(3):538-45.
1981: F Roerdink; J Dijkstra; G Hartman; B Bolscher; Gerrit L Scherphof
The involvement of parenchymal, Kupffer and endothelial liver cells in the hepatic uptake of intravenously injected liposomes. Effects of lanthanum and gadolinium salts.
Biochimica et biophysica acta 1981;677(1):79-89.
1981: P M Lippiello; J Dijkstra; M van Galen; Gerrit L Scherphof; B M Waite
The uptake and metabolism of chylomicron-remnant lipids by nonparenchymal cells in perfused liver and by Kupffer cells in culture.
The Journal of biological chemistry 1981;256(14):7454-60.
1981: H Ellens; Henriëtte W M Morselt; Gerrit L Scherphof
In vivo fate of large unilamellar sphingomyelin-cholesterol liposomes after intraperitoneal and intravenous injection into rats.
Biochimica et biophysica acta 1981;674(1):10-8.
1980: J Damen; J Dijkstra; J Regts; Gerrit L Scherphof
Effect of lipoprotein-free plasma on the interaction of human plasma high density lipoprotein with egg yolk phosphatidylcholine liposomes.
Biochimica et biophysica acta 1980;620(1):90-9.