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Georg Schett

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Carina Scholtysek; Michael Stock; Cornelia Stoll; Jan P Tuckermann; Stefan Uderhardt; Mario M Zaiss; Georg Schett; Christina Böhm; Jean-Pierre David; Béatrice Desvergne; Farida Djouad; Laura Donhauser; Klaus Engelke; He Fu; Andreas Hess; Natacha Ipseiz; Julia Katzenbeisser; Arnd Kleyer; Gerhard Krönke
PPARβ/δ governs Wnt signaling and bone turnover.
Theo S Plantinga; Georg Schett; Wim B van den Berg; Annette H M Van Der Helm-Van Mil; Jos W M van der Meer; Piet L van Riel; Jochen Zwerina; Jaap Fransen; Monique M A Helsen; Rachel Knevel; Mihai G Netea; Leo A B Joosten
Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis.
Tomás Dallos; Christian Datz; Matthias Englbrecht; Enijad Sahinbegovic; Georg Schett; Andreas Stadlmayr; Tanja Stamm; Elmar Aigner; Roland Axmann; Jochen Zwerina
Idiopathic hand osteoarthritis vs haemochromatosis arthropathy--a clinical, functional and radiographic study.

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2013: Carina Scholtysek; Michael Stock; Cornelia Stoll; Jan P Tuckermann; Stefan Uderhardt; Mario M Zaiss; Georg Schett; Christina Böhm; Jean-Pierre David; Béatrice Desvergne; Farida Djouad; Laura Donhauser; Klaus Engelke; He Fu; Andreas Hess; Natacha Ipseiz; Julia Katzenbeisser; Arnd Kleyer; Gerhard Krönke
PPARβ/δ governs Wnt signaling and bone turnover.
Nature medicine 2013;19(5):608-13.
2013: Theo S Plantinga; Georg Schett; Wim B van den Berg; Annette H M Van Der Helm-Van Mil; Jos W M van der Meer; Piet L van Riel; Jochen Zwerina; Jaap Fransen; Monique M A Helsen; Rachel Knevel; Mihai G Netea; Leo A B Joosten
Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis.
Rheumatology (Oxford, England) 2013;52(5):806-14.
2013: Tomás Dallos; Christian Datz; Matthias Englbrecht; Enijad Sahinbegovic; Georg Schett; Andreas Stadlmayr; Tanja Stamm; Elmar Aigner; Roland Axmann; Jochen Zwerina
Idiopathic hand osteoarthritis vs haemochromatosis arthropathy--a clinical, functional and radiographic study.
Rheumatology (Oxford, England) 2013;52(5):910-5.
2013: Neng-Yu Lin; Luis Enrique Munoz; Georg Schett; Carina Scholtysek; Brian Spencer; Stefan Uderhardt; Stefan Wirtz; Christian Beyer; Clara Dees; Alfiya Distler; Oliver Distler; Andreas Giessl; Trayana Kireva; Gerhard Krönke; Jörg H W Distler
Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.
Annals of the rheumatic diseases 2013;72(5):761-8.
2013: Matthias Englbrecht; Madeleine Kruckow; Jürgen Rech; Elizabeth Araujo; Georg Schett
The Interaction of Physical Function and Emotional Well-being in Rheumatoid Arthritis-What is the Impact on Disease Activity and Coping?
Seminars in arthritis and rheumatism 2013;42(5):482-91.
2013: Christian Beyer; Clara Dees; Alfiya Distler; Oliver Distler; Jan Leipe; Louis Munoz; Helena Reichert; Georg Schett; Hendrik Schulze-Koops; Alla Skapenko; Jörg H W Distler
Activation of pregnane X receptor inhibits experimental dermal fibrosis.
Annals of the rheumatic diseases 2013;72(4):621-5.
2013: Tobias Braun; Jörg H W Distler; Matthias Gaestel; Willy Hofstetter; Klaus Klaushofer; Johannes Lepper; Patrick Lezuo; Gisela Ruiz Heiland; Monika Rumpler; Georg Schett; Mark Siegrist; Roman Thaler; Jochen Zwerina
Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013;28(4):936-47.
2013: Günter Weiss; Georg Schett
Anaemia in inflammatory rheumatic diseases.
Nature reviews. Rheumatology 2013;9(4):205-15.
2013: Marlene Krämer; Victor E Marquez; Katrin Palumbo-Zerr; Georg Schett; Inga Schlottmann; Pawel Zerr; Christian Beyer; Clara Dees; Alfiya Distler; Oliver Distler; Kolja Gelse; Jingang Huang; Jörg H W Distler
Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis.
Annals of the rheumatic diseases 2013;72(4):614-20.
2013: Stefan Kiechl; Trayana Kireva; Michael Knoflach; Florian Kronenberg; Julia Luther; Agnes Mayr; James B Meigs; Dirk Mielenz; Alexander R Moschen; Giovanna Muscogiuri; Friedrich Oberhollenzer; Michael Orthofer; Josef M Penninger; Ulrike Billmeier; Enzo Bonora; Aline Bozec; Georg Egger; Andrea Giaccari; Gian Pio Sorice; Monika Summerer; Herbert Tilg; Johann Willeit; Peter Willeit; Stefan Wirtz; Jürgen Wittmann; Georg Schett
Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus.
Nature medicine 2013;19(3):358-63.
2013: Stephanie Finzel; Jürgen Rech; Klaus Engelke; Matthias Englbrecht; Sarah Schmidt; Georg Schett
Interleukin-6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study.
Annals of the rheumatic diseases 2013;72(3):396-400.
2013: Cord Huchzermeyer; Christian Mardin; Georg Schett; Jochen Zwerina; Leonard Holbach; Jürgen Rech
Successful remission induction with a combination therapy of rituximab, cyclophosphamide, and steroids in a patient with refractory optic neuritis in Wegener's granulomatosis.
Clinical rheumatology 2013;32 Suppl 1():S97-101.
2013: Enijad Sahinbegovic; Georg Schett; Christoph Schörner; Stephan Söder; Gunther Arco; Alexander Cavallaro; Thomas Harrer; Jochen Zwerina
A typically atypical tenosynovitis.
Clinical rheumatology 2013;32 Suppl 1():S87-8.
2013: Ulrike Harre; Georg Schett
Bone research in 2012: the ups and downs of bone in health and rheumatic disease.
Nature reviews. Rheumatology 2013;9(2):67-8.
2013: Juergen Rech; Marc Saake; Marina Sergeeva; Arnd Doerfler; Matthias Englbrecht; Stephanie Finzel; Andreas Hess; Silke Kreitz; Georg Schett
Association of brain functional magnetic resonance activity with response to tumor necrosis factor inhibition in rheumatoid arthritis.
Arthritis and rheumatism 2013;65(2):325-33.
2013: Georg Schett; Johann Willeit; Jochen Zwerina; Franz Aschenbrenner; Francis Berenbaum; Maria-Antonietta D'Agostino; Annamaria Iagnocco; Arndt Kleyer; Rolando Lorenzini; Carlo Perricone; Enijad Sahinbegovic; Stefan Kiechl
Diabetes is an independent predictor for severe osteoarthritis: results from a longitudinal cohort study.
Diabetes care 2013;36(2):403-9.
2013: Emma Husar-Memmer; Bernhard Manger; Georg Schett; Heinrich Sticht; Ali Al-Kaissi; Arif Ekici; Jochen Zwerina
Premature osteoarthritis as presenting sign of type II collagenopathy: a case report and literature review.
Seminars in arthritis and rheumatism 2013;42(4):355-60.
2013: Sebastian H Unizony; Jochen Zwerina; Bhaskar Dasgupta; Elena Fisheleva; Olivier Harari; Lucy Rowell; Georg Schett; Robert Spiera; John H Stone
Design of the tocilizumab in giant cell arteritis trial.
International journal of rheumatology 2013;2013():912562.
2013: Ralf Müller; Georg Schett; Betty van der Veen; Kerstin Amann; Tobias Braun; Christoph Daniel; Karlhans Endlich; Peter Heeringa; Christian Hugo; Dirk Mielenz; Jochen Zwerina
The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis.
PloS one 2013;8(2):e56316.
2013: Dominique Baeten; Maxime Breban; Rik Lories; Georg Schett; Joachim Sieper
Are spondylarthritides related but distinct conditions or a single disease with a heterogeneous phenotype?
Arthritis and rheumatism 2013;65(1):12-20.
2013: Philipp Stockmann; Falk Wehrhan; Bernd Wullich; Matthias W Beckmann; Matthias Englbrecht; Peter A Fasching; Thomas Kreusch; Andreas Mackensen; Emeka Nkenke; Claudia Rauh; Georg Schett; Tilo Schlittenbauer; Bernd M Spriewald
Major histocompatibility complex class II polymorphisms are associated with the development of anti-resorptive agent-induced osteonecrosis of the jaw.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2013;41(1):71-5.
2013: Kerstin Sarter; Georg Schett; Martin Schiller; Christine Schorn; Silke Winkler; Sabine André; Laura Andreoli; Martin Herrmann; David A Isenberg; Christina Janko; Herbert Kaltner; Hanns-Martin Lorenz; Angelo A Manfredi; Luis E Muñoz; Jürgen Rech; Hans-Joachim Gabius
Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
Glycobiology 2013;23(1):12-22.
2013: Maxime Dougados; Antony Hou; Karsten Kissel; Emilio Martín Mola; Federico Navarro-Sarabia; Georg Schett; Tom Sheeran; Paul P Tak; Howard Amital; Corrado Bernasconi; Philip Conaghan; T W J Huizinga
Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY).
Annals of the rheumatic diseases 2013;72(1):43-50.
2012: Ulrike Harre; Martin Herrmann; Natacha Ipseiz; Hildegard Keppeler; Michael Aigner; Anja Derer; Kerstin Poller; Georg Schett; Kirsten Lauber
Moonlighting osteoclasts as undertakers of apoptotic cells.
Autoimmunity 2012;45(8):612-9.
2012: Katrin Palumbo-Zerr; Georg Schett; Enrico Selvi; Pawel Zerr; Christian Beyer; Benjamin F Cravatt; Clara Dees; Alfiya Distler; Oliver Distler; Angelika Horn; Jörg H W Distler
Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1.
Annals of the rheumatic diseases 2012;71(12):2051-4.
2012: Arnd Kleyer; Georg Schett; Carina Scholtysek; Jan P Tuckermann; Christian Beyer; Edith Bottesch; Jörg Hw Distler; Ulrike Hillienhof; Gerhard Krönke
Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(12):2442-51.
2012: Benjamin Rhodes; Amy L Roberts; Georg Schett; Tim D Spector; George Tzircotis; Barbara G Fürnrohr; Timothy J Vyse
The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes.
Annals of the rheumatic diseases 2012;71(12):2028-34.
2012: Georg Schett; Ellen Gravallese
Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment.
Nature reviews. Rheumatology 2012;8(11):656-64.
2012: Pawel Zerr; Clara Dees; francesco del galdo; Alfiya Distler; Oliver Distler; Friederike Egberts; Katrin Palumbo-Zerr; Georg Schett; Bernd M Spriewald; Ilaria Tinazzi; Michal Tomcik; Stefan Vollath; Jörg H W Distler
Combined inhibition of c-Abl and PDGF receptors for prevention and treatment of murine sclerodermatous chronic graft-versus-host disease.
The American journal of pathology 2012;181(5):1672-80.
2012: Aisa Khodzhigorova; Veronika Lang; Georg Schett; Holm Schneider; Christian Beyer; Clara Dees; Alfiya Distler; Oliver Distler; Kolja Gelse; Jörg H W Distler
Inhibition of sumoylation prevents experimental fibrosis.
Annals of the rheumatic diseases 2012;71(11):1904-8.
2012: Simon Weingärtner; Pawel Zerr; Christian Beyer; Dorota Cedzik; Clara Dees; Alfiya Distler; Oliver Distler; Katrin Palumbo-Zerr; Peter H Schafer; Georg Schett; Sai L Shankar; Michal Tomcik; Jörg H W Distler
Pomalidomide is effective for prevention and treatment of experimental skin fibrosis.
Annals of the rheumatic diseases 2012;71(11):1895-9.
2012: Dorette Raaz-Schrauder; André Reis; Georg Schett; Jan G J van de Winkel; Reinhard E Voll; Arif B Ekici; Christoph D Garlichs; Lutz Klinghammer; Jeanette H W Leusen; Luis E Munoz; Martin Herrmann
Patients with unstable angina pectoris show an increased frequency of the Fc gamma RIIa R131 allele.
Autoimmunity 2012;45(7):556-64.
2012: Anne-Christine Bay-Jensen; Arndt Kleyer; Diana J Leeming; Georg Schett; Sanne S Veidal; Morten A Karsdal
Ankylosing spondylitis is characterized by an increased turnover of several different metalloproteinase-derived collagen species: a cross-sectional study.
Rheumatology international 2012;32(11):3565-72.
2012: Pawel Zerr; Christian Beyer; Clara Dees; francesco del galdo; Alfiya Distler; Oliver Distler; Friederike Egberts; Luis E Munoz; Katrin Palumbo-Zerr; Georg Schett; Bernd M Spriewald; Ilaria Tinazzi; Michal Tomcik; Stefan Vollath; Jörg H W Distler
Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease.
Blood 2012;120(14):2909-17.
2012: Rüdiger B Müller; Luis E Muñoz; Georg Schett; Ahmed Sheriff; Birgit Vogt; Johannes von Kempis; Silke Winkler; Sandra Franz; Peter Kern; Christian Maihöfner; Martin Herrmann
Detection of low level cryoglobulins by flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012;81(10):883-7.
2012: Georg Schett; Randall Stevens; Adele R Vessey; Jurgen Wollenhaupt; ChiaChi Hu; Rik Joos; Kim Papp; Jude F Rodrigues; Kurt L de Vlam
Oral apremilast in the treatment of active psoriatic arthritis: results of a multicenter, randomized, double-blind, placebo-controlled study.
Arthritis and rheumatism 2012;64(10):3156-67.
2012: Morten A Karsdal; Andy Kenwright; Georg Schett; Anne-Christine Bay-Jensen; Inger Byrjalsen; Paul Emery; Olivier Harari; Adam Platt
IL-6 receptor inhibition positively modulates bone balance in rheumatoid arthritis patients with an inadequate response to anti-tumor necrosis factor therapy: biochemical marker analysis of bone metabolism in the tocilizumab RADIATE study (NCT00106522).
Seminars in arthritis and rheumatism 2012;42(2):131-9.
2012: Christian Beyer; Jörg H W Distler; Adreas Giessl; Georg Schett; Nancy A Stearns; David S Pisetsky
The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death.
Innate immunity 2012;18(5):727-37.
2012: Clara Dees; Alfiya Distler; Christian Beyer; Oliver Distler; Kolja Gelse; Angelika Horn; Veronika Lang; Katrin Palumbo-Zerr; Georg Schett; Michal Tomcik; Pawel Zerr; Jochen Zwerina; Jörg H W Distler
JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.
Arthritis and rheumatism 2012;64(9):3006-15.
2012: Rik J U Lories; Georg Schett
Pathophysiology of new bone formation and ankylosis in spondyloarthritis.
Rheumatic diseases clinics of North America 2012;38(3):555-67.
2012: Britta Maurer; Beat A Michel; Nicole Reich; Georg Schett; Renate E Gay; Steffen GAY; Astrid Juengel; Jörg Kriegsmann; Jörg H W Distler; Oliver Distler
Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis.
Annals of the rheumatic diseases 2012;71(8):1382-7.
2012: Stefan W H Dandorfer; Bernhard Manger; Jürgen Rech; Georg Schett; Matthias Englbrecht
Differences in the patient's and the physician's perspective of disease in psoriatic arthritis.
Seminars in arthritis and rheumatism 2012;42(1):32-41.
2012: Angelika Horn; Katrin Palumbo; Hermine Roudaut; Martial Ruat; Georg Schett; Michal Tomcik; Elisabeth Traiffort; Pawel Zerr; Jochen Zwerina; Alfiya Akhmetshina; Jérome Avouac; Cinzia Cordazzo; Clara Dees; Oliver Distler; J Gusinde; Jörg H W Distler
Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.
Arthritis and rheumatism 2012;64(8):2724-33.
2012: Anna Zampetaki; Chantal M Boulanger; Philip J Chowienczyk; Ignat Drozdov; Stefan Kiechl; Agnes Mayr; Marianna Prokopi; Jean-Marie Renard; Georg Schett; Ajay Shah; Lindsey Tilling; Siegfried Weger; Johann Willeit; Peter Willeit; Manuel Mayr
Prospective study on circulating MicroRNAs and risk of myocardial infarction.
Journal of the American College of Cardiology 2012;60(4):290-9.
2012: C Janko; A A Manfredi; S Muller; L E Munoz; Georg Schett; M Schiller; C Schorn; S Winkler; Sabine André; L Andreoli; J P Briand; Hans-Joachim Gabius; D A Isenberg; Martin Herrmann
Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome.
Lupus 2012;21(7):781-3.
2012: Tobias Braun; Georg Schett
Pathways for bone loss in inflammatory disease.
Current osteoporosis reports 2012;10(2):101-8.
2012: Walter P Maksymowych; Dirk Elewaut; Georg Schett
Motion for debate: the development of ankylosis in ankylosing spondylitis is largely dependent on inflammation.
Arthritis and rheumatism 2012;64(6):1713-9.
2012: Christian Beyer; Clara Dees; Alfiya Akhmetshina; Oliver Distler; Claudia Hirth-Dietrich; Nicole Reich; Peter Sandner; Georg Schett; Sonia C Schindler; Michal Tomcik; Georges von Degenfeld; Jörg H W Distler
Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis.
Annals of the rheumatic diseases 2012;71(6):1019-26.
2012: Carina Scholtysek; Gerhard Krönke; Georg Schett
Inflammation-associated changes in bone homeostasis.
Inflammation & allergy drug targets 2012;11(3):188-95.
2012: Gerhard Krönke; Veronika Lang; Katrin Palumbo; Nicole Reich; Georg Schett; Carina Scholtysek; Stefan Uderhardt; Pawel Zerr; Alfiya Akhmetshina; Clara Dees; Oliver Distler; Jörg H W Distler
The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis.
Annals of the rheumatic diseases 2012;71(6):1081-7.
2012: Adelheid Korb-Pap; Katja Mühlenberg; Birgit Niederreiter; Thomas Pap; Hermann Pavenstädt; Georg Schett; Josef S Smolen; Richard Stange; Athanasios Stratis; Jochen Zwerina; Frank Echtermeyer; Silvia Hayer; Kurt Redlich
Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis.
Annals of the rheumatic diseases 2012;71(6):1004-11.
2012: J Rech; Georg Schett; M Wilhelm; B Lang; Bernhard Manger; Josef Birkmann
Adult-onset Still's disease and chronic recurrent multifocal osteomyelitis: a hitherto undescribed manifestation of autoinflammation.
Rheumatology international 2012;32(6):1827-9.
2012: Stefan Uderhardt; Reinhard E Voll; Susanne Aschermann; Wolfgang Bicker; Valery N Bochkov; Benjamin Frey; Martin Herrmann; Natacha Ipseiz; Falk Nimmerjahn; Olga V Oskolkova; Tobias Rothe; Kerstin Sarter; Georg Schett; Gerhard Krönke
12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance.
Immunity 2012;36(5):834-46.
2012: Ulrike Harre; Per-Johan Jakobsson; Pierre Jurdic; Lars Klareskog; Grit Krumbholz; Elena Neumann; Falk Nimmerjahn; Elena Ossipova; Gabriella Sarmay; Hans-Ulrich Scherer; Roland Axmann; Holger Bang; Wolfgang Baum; Aline Bozec; Anca Irinel Catrina; Dan Georgess; Eszter Szarka; Rene Toes; Georg Schett
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin.
The Journal of clinical investigation 2012;122(5):1791-802.
2012: Angelika Horn; Trayana Kireva; Katrin Palumbo-Zerr; Martial Ruat; Georg Schett; Michal Tomcik; Pawel Zerr; Alfiya Akhmetshina; Christian Beyer; Cinzia Cordazzo; Clara Dees; Oliver Distler; Jörg H W Distler
Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis.
Annals of the rheumatic diseases 2012;71(5):785-9.
2012: Danielle M Gerlag; Johanna M Hazes; Tom W J Huizinga; Lars Klareskog; Tore K Kvien; Cathryn Lewis; Klaus P Machold; Karim Raza; Johan Rönnelid; Georg Schett; Josef S Smolen; Elisabeth Brouwer; Christopher D Buckley; Gerd R Burmester; Anca I Catrina; Andrew P Cope; François Cornelis; Solbritt Rantapää Dahlqvist; Paul Emery; Stephen Eyre; Axel Finckh; Cem Gabay; Steffen Gay; Sue Thomas; Lisa G M van Baarsen; Annette van der Helm-van Mil; Jane Worthington; Dirkjan van Schaardenburg; Paul P Tak
EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis.
Annals of the rheumatic diseases 2012;71(5):638-41.
2012: Christina Böhm; Roland Axmann; Anja Derer; Klaus Engelke; Andreas Hess; Ulrike Hillienhoff; Julia Luther; Georg Schett; Carina Scholtysek; Michael Stock; Jan P Tuckermann; Mario M Zaiss; Christine Zech; Jean-Pierre David
RSK2 protects mice against TNF-induced bone loss.
Journal of cell science 2012;125(Pt 9):2160-71.
2012: H Skjøt-Arkil; Y Wang; C Zhang; Q Zheng; Peter Alexandersen; Anne-Christine Bay-Jensen; Claus Christiansen; Kim Henriksen; D V Larsen; M R Larsen; Diana J Leeming; A Nawrocki; Georg Schett; M A Karsdal
Investigation of two novel biochemical markers of inflammation, matrix metalloproteinase and cathepsin generated fragments of C-reactive protein, in patients with ankylosing spondylitis.
Clinical and experimental rheumatology 2012;30(3):371-9.
2012: Christian Beyer; Benoit de Crombrugghe; Clara Dees; Oliver Distler; Kolja Gelse; Trayana Kireva; Georg Schett; Amelie Schramm; Sonali Sonnylal; Makoto Mark Taketo; Alfiya Akhmetshina; Jörg H W Distler
β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.
Annals of the rheumatic diseases 2012;71(5):761-7.
2012: Christian Beyer; Helmut Klaus; Bernhard Manger; Georg Schett; Michael Vieth; Jochen Zwerina
Strawberry gingivitis.
Joint, bone, spine : revue du rhumatisme 2012;79(3):322.
2012: Nicole Reich; Georg Schett; Michal Tomcik; Weilin Xie; Pawel Zerr; Alfiya Akhmetshina; Jérome Avouac; Brydon L Bennett; Christian Beyer; Clara Dees; Oliver Distler; Angelika Horn; Veronika Lang; Katrin Palumbo; Jörg H W Distler
Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis.
Annals of the rheumatic diseases 2012;71(5):737-45.
2012: Jérôme Avouac; Christian Beyer; Clara Dees; Alfiya Akhmetshina; Yannick Allanore; Oliver Distler; Angelika Horn; Britta Maurer; Katrin Palumbo; Anika Sadowski; Georg Schett; Holm Schneider; Shunichi Shiozawa; Michal Tomcik; Pawel Zerr; Jörg H W Distler
Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
Arthritis and rheumatism 2012;64(5):1642-52.
2012: Cordula Surmann-Schmitt; Klaus von der Mark; Nicole Eitzinger; Takako Hattori; Takako Sasaki; Georg Schett; Michael Stock
The Wnt antagonist Wif-1 interacts with CTGF and inhibits CTGF activity.
Journal of cellular physiology 2012;227(5):2207-16.
2012: Veronika R Lang; Bernhard Manger; Karin Manger; Hubert Nüsslein; Jürgen Rech; Georg Schett; Florian Schuch; Hans-Peter Tony; Matthias Englbrecht; Martin Fleck; Jochen Zwerina
Risk of infections in rheumatoid arthritis patients treated with tocilizumab.
Rheumatology (Oxford, England) 2012;51(5):852-7.
2012: Inessa Schwab; Georg Schett; Markus Biburger; Gerhard Krönke; Falk Nimmerjahn
IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.
European journal of immunology 2012;42(4):826-30.
2012: Gisela Ruiz Heiland; Axel Hueber; Joachim Listing; Denis Poddubnyy; Martin Rudwaleit; Georg Schett; Heiner Appel; Xenofon Baraliakos; Hildrun Haibel; Jochen Zwerina; Joachim Sieper
High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis.
Annals of the rheumatic diseases 2012;71(4):572-4.
2012: Luis E Munoz; Georg Schett; Martin Schiller; Reinhard E Voll; Yi Zhao; Martin Herrmann
Do low vitamin D levels cause problems of waste removal in patients with SLE?
Rheumatology (Oxford, England) 2012;51(4):585-7.
2012: Gisela Ruiz-Heiland; Georg Schett; Michael Stock; Pawel Zerr; Wolfgang Baum; Jörg H Distler; Willy Hofstetter; Angelika Horn; Falk Nimmerjahn; Jochen Zwerina
Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis.
Annals of the rheumatic diseases 2012;71(3):400-7.
2012: Martina Rauner; Georg Schett; Thorsten Schinke; Jochen Schulze; Nicola Stein; Maria Winzer; Jochen Zwerina; Joachim Albers; Martin Bornhäuser; Jörg H W Distler; Claudia Goettsch; Uwe Platzbecker; Lorenz C Hofbauer
WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(3):575-85.
2012: Nicole Eitzinger; Klaus Engelke; Andreas Hess; Georg Schett; Cordula Surmann-Schmitt; Klaus von der Mark; Michael R Bösl; Michael Stock
Ucma is not necessary for normal development of the mouse skeleton.
Bone 2012;50(3):670-80.
2012: Augusto Vaglio; Federico Alberici; Luisita Battistelli; Christian Beyer; Francesco Bonatti; Jörg H W Distler; Bernhard Manger; Federica Maritati; Jürgen Rech; Georg Schett; Renato A Sinico; Johanna D Strehl; Jochen Zwerina
IgG4 immune response in Churg-Strauss syndrome.
Annals of the rheumatic diseases 2012;71(3):390-3.
2012: Bernhard Manger; Georg Schett; J Wacker; M Lell; Jürgen Rech
Detection of periarticular urate deposits with dual energy CT in patients with acute gouty arthritis.
Annals of the rheumatic diseases 2012;71(3):470-2.
2012: Eleni Douni; Elias Eliopoulos; Eleni Makrinou; Josef M Penninger; Vagelis Rinotas; Georg Schett; Jochen Zwerina; George Kollias
A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF.
Human molecular genetics 2012;21(4):784-98.
2012: Matthias Englbrecht; Laure Gossec ; Tore K Kvien; Marieke Scholte-Voshaar; Tuulikki Sokka; Anita Delongis; Georg Schett
The impact of coping strategies on mental and physical well-being in patients with rheumatoid arthritis.
Seminars in arthritis and rheumatism 2012;41(4):545-55.
2012: Karin Zwerina; Wim van den Berg; Mario Zaiss; Jochen Zwerina; Wolfgang Baum; Gisela Ruiz Heiland; Axel Hueber; Leo Joosten; Marije I Koenders; Renoud J Marijnissen; Iain McLnnes; Georg Schett
Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance.
European journal of immunology 2012;42(2):413-23.
2012: Nasim A Khan; Ieda Maria Magalhaes Laurindo; Maria Majdan; Antonio Naranjo; Sapan Pandya; Christof Pohl; Georg Schett; Zahraa I Selim; Esam Abda; Amita Aggarwal; RIEKE ALTEN; Codrina Ancuta; Daina Andersone; Martin Bergman; Jurgen Craig-Muller; Jacqueline Detert; Lia Georgescu; Laure Gossec ; Hisham Hamoud; Johannes W G Jacobs; Horace Spencer; Sergio Toloza; Hisahi Yamanaka; Tuulikki Sokka
Determinants of discordance in patients' and physicians' rating of rheumatoid arthritis disease activity.
Arthritis care & research 2012;64(2):206-14.
2012: Christine Schorn; Yi Zhao; Christina Janko; Veit Krenn; Luis E Munoz; Georg Schett; Martin Herrmann
Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals.
Frontiers in immunology 2012;3():376.
2012: Christine Schorn; Ricardo Chaurio; Christina Janko; Melanie Latzko; Georg Schett; Martin Herrmann
Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells.
Frontiers in immunology 2012;3():277.
2012: Alfiya Akhmetshina; Christina Bergmann; Christian Beyer; Clara Dees; Oliver Distler; Angelika Horn; Trayana Kireva; Ormond A MacDougald; Katrin Palumbo; Marc-Oliver Riener; Anika Sadowski; Georg Schett; Holm Schneider; Paulius Venalis; Pawel Zerr; Jochen Zwerina; Jörg H W Distler
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis.
Nature communications 2012;3():735.
2012: Zsuzsanna Kertész; Katalin Kis-Toth; Szandra Körmendi; Csaba Dobó-Nagy; Tünde Fekete; Dávid Gyori; Zoltan Jakus; Eva Rajnavölgyi; Georg Schett; Attila Mócsai
Phospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption.
European journal of clinical investigation 2012;42(1):49-60.
2011: Georg Schett
Rheumatoid arthritis and multiple sclerosis: direful siblings, different strategies.
FEBS letters 2011;585(23):3601-2.
2011: Christina Bergmann; Christian Beyer; Clara Dees; Oliver Distler; Katrin Palumbo; Georg Schett; Pawel Zerr; Jochen Zwerina; Alfiya Akhmetshina; Jörg H W Distler
Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway.
Annals of the rheumatic diseases 2011;70(12):2191-8.
2011: Georg Schett
Effects of inflammatory and anti-inflammatory cytokines on the bone.
European journal of clinical investigation 2011;41(12):1361-6.
2011: Monika Ronneberger; Georg Schett
Pathophysiology of spondyloarthritis.
Current rheumatology reports 2011;13(5):416-20.
2011: Christian Beyer; Jörg H W Distler; Bernhard Manger; Enijad Sahinbegovic; Georg Schett; Roland Axmann; Jochen Zwerina
Anti-interleukin 6 receptor therapy as rescue treatment for giant cell arteritis.
Annals of the rheumatic diseases 2011;70(10):1874-5.
2011: Jochen Zwerina; Stefan Wieczorek; Christian Bach; Jan Bremer; Guido Hegasy; Maria Jatzwauk; davide martorana; Frank Moosig; Alexander Moschen; Thomas Neumann; Georg Schett; Bernd M Spriewald; Herbert Tilg; Augusto Vaglio
Eotaxin-3 in Churg-Strauss syndrome: a clinical and immunogenetic study.
Rheumatology (Oxford, England) 2011;50(10):1823-7.
2011: George Kollias; Iain McInnes; Piyi Papadaki; Ioannis Ragoussis; Georg Schett; Paul P Tak; Rene Toes; Wim van den Berg; Margriet J Vervoordeldonk; Wolfgang Wurst; Florence Apparailly; Vera Baumans; Christian Desaintes; James Di Santo; Jörg Distler; Paul Garside; Bert 't Hart; Martin Hegen; Rikard Holmdahl; Tom W J Huizinga; Astrid Jüngel; Lars Klareskog; Steffen Gay
Animal models for arthritis: innovative tools for prevention and treatment.
Annals of the rheumatic diseases 2011;70(8):1357-62.
2011: Jörg H W Distler; Tobias Strapatsas; Dörte Huscher; Clara Dees; Alfiya Akhmetshina; Hans P Kiener; Ingo H Tarner; Britta Maurer; Marcel Walder; Beat Michel; Steffen Gay; Josef S Smolen; Ulf Müller-Ladner; Georg Schett; Oliver Distler
Dysbalance of angiogenic and angiostatic mediators in patients with mixed connective tissue disease.
Annals of the rheumatic diseases 2011;70(7):1197-202.
2011: Katrin Palumbo; Pawel Zerr; Michal Tomcik; Stefan Vollath; Clara Dees; Alfiya Akhmetshina; Jerome Avouac; Moshe Yaniv; Oliver Distler; Georg Schett; Jörg H W Distler
The transcription factor JunD mediates transforming growth factor {beta}-induced fibroblast activation and fibrosis in systemic sclerosis.
Annals of the rheumatic diseases 2011;70(7):1320-6.
2011: Charlotte Starke; Vilma Urbonaviciute; Ute Wellmann; Thomas Winkler; Kerstin Amann; Silke Frey; Martin Herrmann; Georg Schett; Reinhard E Voll
High frequency of autoantibody-secreting cells and long-lived plasma cells within inflamed kidneys of NZB/W F1 lupus mice.
European journal of immunology 2011;41(7):2107-12.
2011: Daniel Aeberli; Prisca Eser; Georg Schett; Michael Seitz; Peter M Villiger
Serum Dkk-1 levels of DISH patients are not different from healthy controls.
Joint, bone, spine : revue du rhumatisme 2011;78(4):422-3.
2011: Clara Dees; Michal Tomcik; Pawel Zerr; Alfiya Akhmetshina; Angelika Horn; Katrin Palumbo; Christian Beyer; Jochen Zwerina; Oliver Distler; Georg Schett; Jörg H W Distler
Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis.
Annals of the rheumatic diseases 2011;70(7):1304-10.
2011: Jörg H W Distler; Alfiya Akhmetshina; Clara Dees; Steffen Gay; Astrid Jüngel; David S Pisetsky; Georg Schett; Michael Stürzl; Oliver Distler
Induction of apoptosis in circulating angiogenic cells by microparticles.
Arthritis and rheumatism 2011;63(7):2067-77.
2011: E Sahinbegovic; Georg Schett
[Therapeutic strategies in erosive digital polyarthrosis].
Der Internist 2011;52(6):682-7.
2011: Mario M Zaiss; Mariola Kurowska-Stolarska; Christina Böhm; Regina Gary; Carina Scholtysek; Bartosz Stolarski; James Reilly; Shauna Kerr; Neal L Millar; Thomas Kamradt; Iain B McInnes; Padraic G Fallon; Jean-Pierre David; Foo Y Liew; Georg Schett
IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6097-105.
2011: Karin Zwerina; Wolfgang Baum; Roland Axmann; Gisela Ruiz Heiland; Jörg H W Distler; Josef Smolen; Silvia Hayer; Jochen Zwerina; Georg Schett
Vitamin D receptor regulates TNF-mediated arthritis.
Annals of the rheumatic diseases 2011;70(6):1122-9.
2011: Clara Dees; Alfiya Akhmetshina; Pawel Zerr; Nicole Reich; Katrin Palumbo; Angelika Horn; Astrid Jüngel; Christian Beyer; Gerhard Krönke; Jochen Zwerina; Rudolf Reiter; Natalia Alenina; Luc Maroteaux; Steffen Gay; Georg Schett; Oliver Distler; Jörg H W Distler
Platelet-derived serotonin links vascular disease and tissue fibrosis.
The Journal of experimental medicine 2011;208(5):961-72.
2011: Stephanie Finzel; Sarah Ohrndorf; Matthias Englbrecht; Christian Stach; Janin Messerschmidt; Georg Schett; Marina Backhaus
A detailed comparative study of high-resolution ultrasound and micro-computed tomography for detection of arthritic bone erosions.
Arthritis and rheumatism 2011;63(5):1231-6.
2011: Julia Luther; Frank Driessler; Matthias Megges; Andreas Hess; Bettina Herbort; Vice Mandic; Mario M Zaiss; Anne Reichardt; Christine Zech; Jan P Tuckermann; Cornelis F Calkhoven; Erwin F Wagner; Georg Schett; Jean-Pierre David
Elevated Fra-1 expression causes severe lipodystrophy.
Journal of cell science 2011;124(Pt 9):1465-76.
2011: Clara Dees; Pawel Zerr; Michal Tomcik; Christian Beyer; Angelika Horn; Alfiya Akhmetshina; Katrin Palumbo; Nicole Reich; Jochen Zwerina; Michael Sticherling; Mark P Mattson; Oliver Distler; Georg Schett; Jörg H W Distler
Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis.
Arthritis and rheumatism 2011;63(5):1396-404.
2011: Trayana Kireva; Annette Erhardt; Gisa Tiegs; Herbert Tilg; Helmut Denk; Johannes Haybaeck; Elmar Aigner; Alexander Moschen; Jörg H Distler; Georg Schett; Jochen Zwerina
Transcription factor Fra-1 induces cholangitis and liver fibrosis.
Hepatology (Baltimore, Md.) 2011;53(4):1259-69.
2011: Georg Schett
Structural bone changes in spondyloarthritis: mechanisms, clinical impact and therapeutic considerations.
The American journal of the medical sciences 2011;341(4):269-71.
2011: Bernhard Manger; Jochen Wacker; Daniela Schmidt; Torsten Kuwert; Alexander Cavallaro; Georg Schett
Clinical Images: Hippokrates confirmed by positron emission tomography.
Arthritis and rheumatism 2011;63(4):1150.
2011: Jochen Schulze; Thomas Bickert; Frank Timo Beil; Mario M Zaiss; Joachim Albers; Kristofer Wintges; Thomas Streichert; Kristin Klaetschke; Johannes Keller; Tim-Nicolas Hissnauer; Alexander S Spiro; Andre Gessner; Georg Schett; Michael Amling; Andrew N J McKenzie; Andrea Kristina Horst; Thorsten Schinke
Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(4):704-17.
2011: Nicole Reich; Christian Beyer; Kolja Gelse; Alfiya Akhmetshina; Clara Dees; Jochen Zwerina; Georg Schett; Oliver Distler; Jörg H W Distler
Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts.
Journal of cellular and molecular medicine 2011;15(4):756-62.
2011: Jérôme Avouac; Barbara G Fürnrohr; Michal Tomcik; Katrin Palumbo; Pawel Zerr; Angelika Horn; Clara Dees; Alfiya Akhmetshina; Christian Beyer; Oliver Distler; Georg Schett; Yannick Allanore; Jörg H W Distler
Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis.
Arthritis and rheumatism 2011;63(3):800-9.
2011: Karin Polzer; Kirsten Neubert; Silke Meister; Benjamin Frey; Wolfgang Baum; Jörg H Distler; Eva Gückel; Georg Schett; Reinhard E Voll; Jochen Zwerina
Proteasome inhibition aggravates tumor necrosis factor-mediated bone resorption in a mouse model of inflammatory arthritis.
Arthritis and rheumatism 2011;63(3):670-80.
2011: Andreas Hess; Roland Axmann; Juergen Rech; Stefanie Finzel; Cornelia Heindl; Silke Kreitz; Marina Sergeeva; Marc Saake; Meritxell Garcia; george kollias; Rainer H Straub; Olaf Sporns; Arnd Doerfler; Kay Brune; Georg Schett
Blockade of TNF-α rapidly inhibits pain responses in the central nervous system.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3731-6.
2011: Rita Rugienė; Jolanta Dadonienė; Eduardas Aleknavičius; Renatas Tikuišis; Jörg Distler; Georg Schett; Paulius Venalis; Algirdas Venalis
Prevalence of paraneoplastic rheumatic syndromes and their antibody profile among patients with solid tumours.
Clinical rheumatology 2011;30(3):373-80.
2011: Juergen Rech; Monika Ronneberger; Matthias Englbrecht; Stephanie Finzel; Julia Katzenbeisser; Karin Manger; Bernhard Manger; Georg Schett
Successful treatment of adult-onset Still's disease refractory to TNF and IL-1 blockade by IL-6 receptor blockade.
Annals of the rheumatic diseases 2011;70(2):390-2.
2011: Christine Schorn; Benjamin Frey; Kirsten Lauber; Christina Janko; Moritz Strysio; Hildegard Keppeler; Udo S Gaipl; Reinhard E Voll; Eva Springer; Luis E Munoz; Georg Schett; Martin Herrmann
Sodium overload and water influx activate the NALP3 inflammasome.
The Journal of biological chemistry 2011;286(1):35-41.
2011: Christina Janko; Kirsten Lauber; Luis E Munoz; Georg Schett; Ahmed Sheriff; Stefan Siebig; Johan Van der Vlag; Silke Winkler; Sandra Franz; Martin Herrmann
CRP/anti-CRP antibodies assembly on the surfaces of cell remnants switches their phagocytic clearance toward inflammation.
Frontiers in immunology 2011;2():70.
2011: Ulrike Harre; Georg Schett; Christine Schorn; Anja Derer; Martin Herrmann
T cells as key players for bone destruction in gouty arthritis?
Arthritis research & therapy 2011;13(6):135.
2011: Eva Gückel; Silke Frey; Mario M Zaiss; Georg Schett; Sankar Ghosh; Reinhard E Voll
Cell-intrinsic NF-κB activation is critical for the development of natural regulatory T cells in mice.
PloS one 2011;6(5):e20003.
2011: Georg Schett; Laura C Coates; Zoe R Ash; Stefanie Finzel; Phillip G Conaghan
Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future.
Arthritis research & therapy 2011;13 Suppl 1():S4.
2011: Morten A Karsdal; Walter P Maksymowych; Adam Platt; Per Qvist; Georg Schett; Tanja Schubert; Philippe Vergnaud; Thasia Woodworth; Claus Christiansen; Harry Genant; Kim Henriksen; Anne-Christine Bay-Jensen
Biochemical markers of ongoing joint damage in rheumatoid arthritis--current and future applications, limitations and opportunities.
Arthritis research & therapy 2011;13(2):215.
2011: Stephanie Finzel; Matthias Englbrecht; Klaus Engelke; Christian Stach; Georg Schett
A comparative study of periarticular bone lesions in rheumatoid arthritis and psoriatic arthritis.
Annals of the rheumatic diseases 2011;70(1):122-7.
2010: Georg Schett; Jean-Pierre David
The multiple faces of autoimmune-mediated bone loss.
Nature reviews. Endocrinology 2010;6(12):698-706.
2010: Gisela Ruiz Heiland; Karin Zwerina; Wolfgang Baum; Trayana Kireva; Jörg H Distler; Mario Grisanti; Frank Asuncion; Xiadong Li; Michael Ominsky; William Richards; Georg Schett; Jochen Zwerina
Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression.
Annals of the rheumatic diseases 2010;69(12):2152-9.
2010: Enijad Sahinbegovic; Tomáš Dallos; Elmar Aigner; Roland Axmann; Bernhard Manger; Matthias Englbrecht; Maximilian Schöniger-Hekele; Thomas Karonitsch; Tanja Stamm; Martin Farkas; Thomas Karger; Ulrich Stölzel; Gernot Keysser; Christian Datz; Georg Schett; Jochen Zwerina
Musculoskeletal disease burden of hereditary hemochromatosis.
Arthritis and rheumatism 2010;62(12):3792-8.
2010: Christian K Weber; Martin Haslbeck; Matthias Englbrecht; Bettina Sehnert; Dirk Mielenz; Daniela Graef; Jörg H W Distler; Ruediger B Mueller; Harald Burkhardt; Georg Schett; Reinhard E Voll; Barbara G Fürnrohr
Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus.
Rheumatology (Oxford, England) 2010;49(12):2255-63.
2010: Tomás Dallos; Enijad Sahinbegovic; Elmar Aigner; Roland Axmann; Maximilian Schöniger-Hekele; Thomas Karonitsch; Tanja Stamm; Martin Farkas; Thomas Karger; Alexander Cavallaro; Ulrich Stölzel; Gernot Keysser; Christian Datz; Georg Schett; Bernhard Manger; Jochen Zwerina
Validation of a radiographic scoring system for haemochromatosis arthropathy.
Annals of the rheumatic diseases 2010;69(12):2145-51.
2010: Daniel Schramek; Andreas Leibbrandt; Verena Sigl; Lukas Kenner; J Andrew Pospisilik; Heather J Lee; Reiko Hanada; Purna A Joshi; Antonios Aliprantis; Laurie Glimcher; Manolis Pasparakis; Rama Khokha; Christopher J Ormandy; Martin Widschwendter; Georg Schett; Josef M Penninger
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.
Nature 2010;468(7320):98-102.
2010: Veronika R Lang; Dirk Mielenz; Kirsten Neubert; Christina Böhm; Georg Schett; Hans-Martin Jäck; Reinhard E Voll; Silke Meister
The early marginal zone B cell-initiated T-independent type 2 response resists the proteasome inhibitor bortezomib.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5637-47.
2010: Luis E Muñoz; Christina Janko; Connie Schulze; Christine Schorn; Kerstin Sarter; Georg Schett; Martin Herrmann
Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE.
Autoimmunity reviews 2010;10(1):38-42.
2010: Tomáš Dallos; Gisela Ruiz Heiland; Johanna Strehl; Thomas Karonitsch; Wolfgang L Gross; Frank Moosig; Constanze Holl-Ulrich; Jörg H W Distler; Bernhard Manger; Georg Schett; Jochen Zwerina
CCL17/thymus and activation-related chemokine in Churg-Strauss syndrome.
Arthritis and rheumatism 2010;62(11):3496-503.
2010: Sieglinde Marquart; Pawel Zerr; Alfiya Akhmetshina; Katrin Palumbo; Nicole Reich; Michal Tomcik; Angelika Horn; Clara Dees; Matthias Engel; Jochen Zwerina; Oliver Distler; Georg Schett; Jörg H W Distler
Inactivation of the cannabinoid receptor CB1 prevents leukocyte infiltration and experimental fibrosis.
Arthritis and rheumatism 2010;62(11):3467-76.
2010: Barbara G Fürnrohr; Sven Wach; Jennifer A Kelly; Martin Haslbeck; Christian K Weber; Christian M Stach; Axel J Hueber; Daniela Graef; Bernd M Spriewald; Karin Manger; Martin Herrmann; Kenneth M Kaufman; Summer G Frank; Ellen Goodmon; Judith A James; Georg Schett; Thomas H Winkler; John B Harley; Reinhard E Voll
Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus.
Annals of the rheumatic diseases 2010;69(11):1983-9.
2010: Georg Schett; Victor S Sloan; Randall M Stevens; Peter Schafer
Apremilast: a novel PDE4 inhibitor in the treatment of autoimmune and inflammatory diseases.
Therapeutic advances in musculoskeletal disease 2010;2(5):271-8.
2010: Christian Beyer; Georg Schett; Oliver Distler; Jörg H W Distler
Animal models of systemic sclerosis: prospects and limitations.
Arthritis and rheumatism 2010;62(10):2831-44.
2010: Bernhard Manger; J Rech; Georg Schett
Use of methotrexate in adult-onset Still's disease.
Clinical and experimental rheumatology 2010;28(5 Suppl 61):S168-71.
2010: Kristin Kruse; Christina Janko; Vilma Urbonaviciute; Claudia T Mierke; Thomas H Winkler; Reinhard E Voll; Georg Schett; Luis E Muñoz; Martin Herrmann
Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.
Apoptosis : an international journal on programmed cell death 2010;15(9):1098-113.
2010: Christian Beyer; Georg Schett
Pharmacotherapy: concepts of pathogenesis and emerging treatments. Novel targets in bone and cartilage.
Best practice & research. Clinical rheumatology 2010;24(4):489-96.
2010: Georg Schett; Kenneth G Saag; Johannes W J Bijlsma
From bone biology to clinical outcome: state of the art and future perspectives.
Annals of the rheumatic diseases 2010;69(8):1415-9.
2010: Gerhard Krönke; Stefan Uderhardt; Kyung-Ah Kim; Michael Stock; Carina Scholtysek; Mario M Zaiss; Cordula Surmann-Schmitt; Julia Luther; Julia Katzenbeisser; Jean-Pierre David; Shahla Abdollahi-Roodsaz; Karolyn Tran; Jessica M Bright; Minke E Binnerts; Alfiya Akhmetshina; Christina Böhm; Jörg H Distler; Leo A B Joosten; Georg Schett; Arie Abo
R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway.
Arthritis and rheumatism 2010;62(8):2303-12.
2010: Mario M Zaiss; Kerstin Sarter; Andreas Hess; Klaus Engelke; Christina Böhm; Falk Nimmerjahn; Reinhard E Voll; Georg Schett; Jean-Pierre David
Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation.
Arthritis and rheumatism 2010;62(8):2328-38.
2010: Daniel Cejka; Silvia Hayer; Birgit Niederreiter; Wolfgang Sieghart; Thorsten Fuereder; Jochen Zwerina; Georg Schett
Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis.
Arthritis and rheumatism 2010;62(8):2294-302.
2010: Georg Schett; Jochen Zwerina; Roland Axmann; Johann Willeit; Kiechl Stefan
Risk prediction for severe osteoarthritis.
Annals of the rheumatic diseases 2010;69(8):1573-4.
2010: Silke Meister; Benjamin Frey; Veronika R Lang; Udo S Gaipl; Georg Schett; Ursula Schlötzer-Schrehardt; Reinhard E Voll
Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells.
Neoplasia (New York, N.Y.) 2010;12(7):550-61.
2010: Enijad Sahinbegovic; Tomás Dallos; Elmar Aigner; Roland Axmann; Matthias Engelbrecht; Maximilian Schöniger-Hekele; Thomas Karonitsch; Martin Farkas; Thomas Karger; Johann Willeit; Ulrich Stölzel; Gernot Keysser; Christian Datz; Stefan Kiechl; Georg Schett; Jochen Zwerina
Hereditary hemochromatosis as a risk factor for joint replacement surgery.
The American journal of medicine 2010;123(7):659-62.
2010: Friederike D Von Loewenich; Walter Geissdörfer; Claudia Disqué; Jens Matten; Georg Schett; Samir G Sakka; Christian Bogdan
Detection of "Candidatus Neoehrlichia mikurensis" in two patients with severe febrile illnesses: evidence for a European sequence variant.
Journal of clinical microbiology 2010;48(7):2630-5.
2010: Oleg Museyko; Fabian Eisa; Andreas Hess; Georg Schett; Willi A Kalender; Klaus Engelke
Binary segmentation masks can improve intrasubject registration accuracy of bone structures in CT images.
Annals of biomedical engineering 2010;38(7):2464-72.
2010: M Englbrecht; Y Wang; M Ronneberger; Bernhard Manger; N Vastesaeger; douglas veale; Georg Schett
Measuring joint involvement in polyarticular psoriatic arthritis: an introduction of alternatives.
Arthritis care & research 2010;62(7):977-83.
2010: Mario M Zaiss; Benjamin Frey; Andreas Hess; Jochen Zwerina; Julia Luther; Falk Nimmerjahn; Klaus Engelke; George Kollias; Thomas Hünig; Georg Schett; Jean-Pierre David
Regulatory T cells protect from local and systemic bone destruction in arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):7238-46.
2010: Georg Schett; Martin Rudwaleit
Can we stop progression of ankylosing spondylitis?
Best practice & research. Clinical rheumatology 2010;24(3):363-71.
2010: Stephan Blüml; Nikolaus B Binder; Birgit Niederreiter; Karin Polzer; Silvia Hayer; Stefanie Tauber; Georg Schett; Clemens Scheinecker; George Kollias; Edgar Selzer; Martin Bilban; Josef S Smolen; Giulio Superti-Furga; Kurt Redlich
Antiinflammatory effects of tumor necrosis factor on hematopoietic cells in a murine model of erosive arthritis.
Arthritis and rheumatism 2010;62(6):1608-19.
2010: Gisela Ruiz Heiland; Elmar Aigner; Tomás Dallos; Enijad Sahinbegovic; Veit Krenn; Christoph Thaler; Günter Weiss; Jörg H W Distler; Christian Datz; Georg Schett; Jochen Zwerina
Synovial immunopathology in haemochromatosis arthropathy.
Annals of the rheumatic diseases 2010;69(6):1214-9.
2010: Alfiya Akhmetshina; Jürgen Beer; Karin Zwerina; Matthias Englbrecht; Katrin Palumbo; Clara Dees; Nicole Reich; Jochen Zwerina; Gabriella Szucs; J Gusinde; Tatiana Nevskaya; Oliver Distler; Dontscho Kerjaschki; Georg Schett; Jörg H W Distler
Decreased lymphatic vessel counts in patients with systemic sclerosis: association with fingertip ulcers.
Arthritis and rheumatism 2010;62(5):1513-22.
2010: Luis E Munoz; Christina Janko; Ricardo A Chaurio; Georg Schett; Udo S Gaipl; Martin Herrmann
IgG opsonized nuclear remnants from dead cells cause systemic inflammation in SLE.
Autoimmunity 2010;43(3):232-5.
2010: Christine Schorn; Moritz Strysio; Christina Janko; Luis E Munoz; Georg Schett; Martin Herrmann
The uptake by blood-borne phagocytes of monosodium urate is dependent on heat-labile serum factor(s) and divalent cations.
Autoimmunity 2010;43(3):236-8.
2010: Mathias Grunke; Christian E Antoni; Arthur Kavanaugh; Verena Hildebrand; Claudia Dechant; Georg Schett; Bernhard Manger; Monika Ronneberger
Standardization of joint examination technique leads to a significant decrease in variability among different examiners.
The Journal of rheumatology 2010;37(4):860-4.
2010: S Uderhardt; D Diarra; J Katzenbeisser; Jean-Pierre David; Jochen Zwerina; W Richards; G Kronke; Georg Schett
Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints.
Annals of the rheumatic diseases 2010;69(3):592-7.
2010: Christian Stach; Michael Bäuerle; Matthias Englbrecht; Gerhard Kronke; Klaus Engelke; Bernhard Manger; Georg Schett
Periarticular bone structure in rheumatoid arthritis patients and healthy individuals assessed by high-resolution computed tomography.
Arthritis and rheumatism 2010;62(2):330-9.
2010: Cornelia Heindl-Erdmann; Roland Axmann; Silke Kreitz; Jochen Zwerina; Josef Penninger; Georg Schett; Kay Brune; Andreas Hess
Combining functional magnetic resonance imaging with mouse genomics: new options in pain research.
Neuroreport 2010;21(1):29-33.
2010: Jean-Pierre David; Georg Schett
TNF and bone.
Current directions in autoimmunity 2010;11():135-44.
2010: Nicole Reich; Britta Maurer; Alfiya Akhmetshina; Paulius Venalis; Clara Dees; Pawel Zerr; Katrin Palumbo; Jochen Zwerina; Tatiana Nevskaya; Steffen Gay; Oliver Distler; Georg Schett; Jörg H W Distler
The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.
Arthritis and rheumatism 2010;62(1):280-90.
2010: Karin Polzer; Leo A B Joosten; J Gasser; Jörg H W Distler; G Ruiz; W Baum; Kurt Redlich; K Bobacz; Josef S Smolen; W van den Berg; Georg Schett; Jochen Zwerina
Interleukin-1 is essential for systemic inflammatory bone loss.
Annals of the rheumatic diseases 2010;69(1):284-90.
2009: Britta Maurer; Nicole Busch; Astrid Jüngel; Margarita Pileckyte; Renate E Gay; Beat A Michel; Georg Schett; Steffen GAY; Jörg Distler; Oliver Distler
Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis.
Circulation 2009;120(23):2367-76.
2009: Silvia Hayer; Noreen Pundt; Marvin A Peters; Christina Wunrau; Inga Kühnel; Katja Neugebauer; Simon Strietholt; Jochen Zwerina; Adelheid Korb; Josef Penninger; Leo A B Joosten; Steffen Gay; Thomas Rückle; Georg Schett; Thomas Pap
PI3Kgamma regulates cartilage damage in chronic inflammatory arthritis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(12):4288-98.
2009: Maria Elena Manea; Ruediger B Mueller; Doru Dejica; Ahmed Sheriff; Georg Schett; Martin Herrmann; Peter Kern
Increased expression of CD154 and FAS in SLE patients' lymphocytes.
Rheumatology international 2009;30(2):181-5.
2009: Stefan Kiechl; Johann Willeit; Georg Schett
Denosumab, osteoporosis, and prevention of fractures.
The New England journal of medicine 2009;361(22):2188-9; author reply 2190-1.
2009: Heiner Appel; Gisela Ruiz-Heiland; Joachim Listing; Jochen Zwerina; Martin Herrmann; Ruediger Mueller; Hildrun Haibel; Xenofon Baraliakos; Axel Hempfing; Martin Rudwaleit; Joachim Sieper; Georg Schett
Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis.
Arthritis and rheumatism 2009;60(11):3257-62.
2009: Camilla I Svensson; Tomoyuki Inoue; Deepa Hammaker; Akihisa Fukushima; Salvatore Papa; Guido Franzoso; Georg Schett; Maripat Corr; David L Boyle; Gary S Firestein
Gadd45beta deficiency in rheumatoid arthritis: enhanced synovitis through JNK signaling.
Arthritis and rheumatism 2009;60(11):3229-40.
2009: Jörg H W Distler; Christian Beyer; Georg Schett; Thomas F Lüscher; Steffen Gay; Oliver Distler
Endothelial progenitor cells: novel players in the pathogenesis of rheumatic diseases.
Arthritis and rheumatism 2009;60(11):3168-79.
2009: Christina Böhm; Silvia Hayer; Anita Kilian; Mario M Zaiss; Susann Finger; Andreas Hess; Klaus Engelke; George Kollias; Gerhard Krönke; Jochen Zwerina; Georg Schett; Jean-Pierre David
The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(9):5938-47.
2009: Cordula Surmann-Schmitt; Nathalie Widmann; Uwe Dietz; Bernhard Saeger; Nicole Eitzinger; Yukio Nakamura; Marianne Rattel; Richard Latham; Christine Hartmann; Helga von der Mark; Georg Schett; Klaus von der Mark; Michael Stock
Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis.
Journal of cell science 2009;122(Pt 20):3627-37.
2009: Paulius Venalis; Britta Maurer; Alfiya Akhmetshina; Nicole Busch; Clara Dees; Michael Stürzl; Jochen Zwerina; Astrid Jüngel; Steffen Gay; Georg Schett; Oliver Distler; Jörg H W Distler
Lack of inhibitory effects of the anti-fibrotic drug imatinib on endothelial cell functions in vitro and in vivo.
Journal of cellular and molecular medicine 2009;13(10):4185-91.
2009: Jochen Zwerina; Gerhard Eger; Matthias Englbrecht; Bernhard Manger; Georg Schett
Churg-Strauss syndrome in childhood: a systematic literature review and clinical comparison with adult patients.
Seminars in arthritis and rheumatism 2009;39(2):108-15.
2009: Georg Schett; Marina Stolina; Denise Dwyer; Debra Zack; Stefan Uderhardt; Gerhard Krönke; Paul Kostenuik; Ulrich Feige
Tumor necrosis factor alpha and RANKL blockade cannot halt bony spur formation in experimental inflammatory arthritis.
Arthritis and rheumatism 2009;60(9):2644-54.
2009: Roland Axmann; Christina Böhm; Gerhard Krönke; Jochen Zwerina; Josef Smolen; Georg Schett
Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo.
Arthritis and rheumatism 2009;60(9):2747-56.
2009: Gerhard Krönke; Julia Katzenbeisser; Stefan Uderhardt; Mario M Zaiss; Carina Scholtysek; Gernot Schabbauer; Alexander Zarbock; Marije I Koenders; Roland Axmann; Jochen Zwerina; Hans W Baenckler; Wim van den Berg; Reinhard E Voll; Hartmut Kühn; Leo A B Joosten; Georg Schett
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):3383-9.
2009: Jochen Wacker; Rene Handschu; Bernhard Manger; Georg Schett; Jochen Zwerina
Sudden visual loss in a patient with microscopic polyangiitis.
Rheumatology (Oxford, England) 2009;48(9):1173-4.
2009: Georg Schett; Stefan Kiechl; Enzo Bonora; Jochen Zwerina; Agnes Mayr; Roland Axmann; Siegfried Weger; Friedrich Oberhollenzer; Rolando Lorenzini; Johann Willeit
Vascular cell adhesion molecule 1 as a predictor of severe osteoarthritis of the hip and knee joints.
Arthritis and rheumatism 2009;60(8):2381-9.
2009: Toshio Yoshizawa; Deepa Hammaker; David L Boyle; Maripat Corr; Richard Flavell; Roger Davis; Georg Schett; Gary S Firestein
Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1360-7.
2009: Georg Schett; J Sieper
Inflammation and repair mechanisms.
Clinical and experimental rheumatology 2009;27(4 Suppl 55):S33-5.
2009: Thomas Neumann; Bernhard Manger; Michael Schmid; Claus Kroegel; Andreas Hansch; Werner A Kaiser; Dirk Reinhardt; Gunter Wolf; Gert Hein; Gerhard Mall; Georg Schett; Jochen Zwerina
Cardiac involvement in Churg-Strauss syndrome: impact of endomyocarditis.
Medicine 2009;88(4):236-43.
2009: Robert A Colbert; Atulya A Deodhar; David Fox; Ellen M Gravallese; Muhammad Asim Khan; Dennis McGonagle; John D Reveille; Georg Schett; Michael Weisman; Daniel O Clegg
Entheses and bones in spondyloarthritis: 2008 Annual Research and Education Meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN).
The Journal of rheumatology 2009;36(7):1527-31.
2009: Georg Schett; Steven L Teitelbaum
Osteoclasts and arthritis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(7):1142-6.
2009: Luis E Muñoz; Christina Janko; Gerhard E Grossmayer; Benjamin Frey; Reinhard E Voll; Peter Kern; Joachim R Kalden; Georg Schett; Rainer Fietkau; Martin Herrmann; Udo S Gaipl
Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus.
Arthritis and rheumatism 2009;60(6):1733-42.
2009: Gerhard Krönke; Stefan Uderhardt; Julia Katzenbeisser; Georg Schett
The 12/15-lipoxygenase pathway promotes osteoclast development and differentiation.
Autoimmunity 2009;42(4):383-5.
2009: Jochen Zwerina; Roland Axmann; Maria Jatzwauk; Enijad Sahinbegovic; Karin Polzer; Georg Schett
Pathogenesis of Churg-Strauss syndrome: recent insights.
Autoimmunity 2009;42(4):376-9.
2009: Benjamin Frey; Udo S Gaipl; Kerstin Sarter; M M Zaiss; W Stillkrieg; Franz Rödel; Georg Schett; Martin Herrmann; Rainer Fietkau; Ludwig Keilholz
Whole body low dose irradiation improves the course of beginning polyarthritis in human TNF-transgenic mice.
Autoimmunity 2009;42(4):346-8.
2009: Christine Schorn; Christina Janko; Luis E Munoz; Connie Schulze; Moritz Strysio; Georg Schett; Martin Herrmann
Sodium and potassium urate crystals differ in their inflammatory potential.
Autoimmunity 2009;42(4):314-6.
2009: Vilma Urbonaviciute; Silke Meister; Barbara G Fürnrohr; Benjamin Frey; Eva Gückel; Georg Schett; Martin Herrmann; Reinhard E Voll
Oxidation of the alarmin high-mobility group box 1 protein (HMGB1) during apoptosis.
Autoimmunity 2009;42(4):305-7.
2009: Christina Janko; Christine Schorn; Daniela Weidner; Kerstin Sarter; Ricardo Chaurio; Ahmed Sheriff; Georg Schett; Luis E Munoz
Treatment with DNAse I fosters binding to nec PBMC of CRP.
Autoimmunity 2009;42(4):286-8.
2009: Luis E Muñoz; Ricardo A Chaurio; Udo S Gaipl; Georg Schett; Peter Kern
MoMa from patients with systemic lupus erythematosus show altered adhesive activity.
Autoimmunity 2009;42(4):269-71.
2009: Georg Schett; Hélène Dumortier; E Hoefler; Sylviane Muller; Günter Steiner
B cell epitopes of the heterogeneous nuclear ribonucleoprotein A2: identification of a new specific antibody marker for active lupus disease.
Annals of the rheumatic diseases 2009;68(5):729-35.
2009: Alfiya Akhmetshina; Clara Dees; Nicole Busch; Jürgen Beer; Kerstin Sarter; Jochen Zwerina; Andreas Zimmer; Oliver Distler; Georg Schett; Jörg H W Distler
The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis.
Arthritis and rheumatism 2009;60(4):1129-36.
2009: Georg Schett
Bone marrow edema.
Annals of the New York Academy of Sciences 2009;1154():35-40.
2009: Jochen Zwerina; Roland Axmann; Bernhard Manger; Georg Schett
The emergence of antineutrophil cytoplasmic antibodies may precede the clinical onset of Churg-Strauss syndrome.
Arthritis and rheumatism 2009;60(2):626-7.
2009: Jörg H W Distler; A Akhmetshina; Georg Schett; Oliver Distler
Monocyte chemoattractant proteins in the pathogenesis of systemic sclerosis.
Rheumatology (Oxford, England) 2009;48(2):98-103.
2009: Kerstin Sarter; Sabine André; Herbert Kaltner; Martin Lensch; Connie Schulze; Vilma Urbonaviciute; Georg Schett; Martin Herrmann; Hans-Joachim Gabius
Detection and chromatographic removal of lipopolysaccharide in preparations of multifunctional galectins.
Biochemical and biophysical research communications 2009;379(1):155-9.
2009: Marina Stolina; Georg Schett; Denise Dwyer; Steven Vonderfecht; Scot Middleton; Diane Duryea; Efrain Pacheco; Gwyneth Van; Brad Bolon; Ulrich Feige; Debra Zack; Paul J Kostenuik
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies.
Arthritis research & therapy 2009;11(6):R187.
2009: Georg Schett
Bone formation versus bone resorption in ankylosing spondylitis.
Advances in experimental medicine and biology 2009;649():114-21.
2009: Christian Beyer; Georg Schett; Steffen Gay; Oliver Distler; Jörg H W Distler
Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis.
Arthritis research & therapy 2009;11(2):220.
2009: Georg Schett
Osteoimmunology in rheumatic diseases.
Arthritis research & therapy 2009;11(1):210.
2009: Alfiya Akhmetshina; Paulius Venalis; Clara Dees; Nicole Busch; Jochen Zwerina; Georg Schett; Oliver Distler; Jörg H W Distler
Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis.
Arthritis and rheumatism 2009;60(1):219-24.
2008: Vilma Urbonaviciute; Barbara G Fürnrohr; Silke Meister; Luis Munoz; Petra Heyder; Francesco De Marchis; Marco E Bianchi; Carsten Kirschning; Hermann Wagner; angelo manfredi; Joachim R Kalden; Georg Schett; Patrizia Rovere-Querini; Martin Herrmann; Reinhard E Voll
Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE.
The Journal of experimental medicine 2008;205(13):3007-18.
2008: Georg Schett; Jean-Pierre David
Denosumab--a novel strategy to prevent structural joint damage in patients with RA?
Nature clinical practice. Rheumatology 2008;4(12):634-5.
2008: Roland Axmann; S Herman; M Zaiss; Sandra Franz; Karin Polzer; Jochen Zwerina; Martin Herrmann; Josef Smolen; Georg Schett
CTLA-4 directly inhibits osteoclast formation.
Annals of the rheumatic diseases 2008;67(11):1603-9.
2008: Karin Polzer; D Baeten; A Soleiman; Jörg H W Distler; D M Gerlag; P P Tak; Georg Schett; Jochen Zwerina
Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints.
Annals of the rheumatic diseases 2008;67(11):1610-6.
2008: G E Grossmayer; Luis E Munoz; C K Weber; Sandra Franz; Reinhard E Voll; Peter M Kern; Joachim R Kalden; Georg Schett; Martin Herrmann; Udo S Gaipl
IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera.
Annals of the rheumatic diseases 2008;67(11):1626-32.
2008: Jürgen Rech; Axel J Hueber; Jan Leipe; Bernhard Manger; Georg Schett; Stefan Kallert
A case report of plasma exchange, steroids, mycophenolate mofetil and cyclophosphamide in acquired factor VIII inhibitors.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2008;12(5):406-8.
2008: Georg Schett; Christian Stach; Jochen Zwerina; Reinhard E Voll; Bernhard Manger
How antirheumatic drugs protect joints from damage in rheumatoid arthritis.
Arthritis and rheumatism 2008;58(10):2936-48.
2008: Sonja Herman; Ruediger B Müller; Gerhard Krönke; Jochen Zwerina; Kurt Redlich; Axel J Hueber; Holger Gelse; Elena Neumann; Ulf Müller-Ladner; Georg Schett
Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis.
Arthritis and rheumatism 2008;58(10):3041-50.
2008: Silvia Hayer; Karin Polzer; Andreas Brandl; Jochen Zwerina; Trayana Kireva; Josef S Smolen; Georg Schett
B-cell infiltrates induce endosteal bone formation in inflammatory arthritis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(10):1650-60.
2008: Georg Schett; Jochen Zwerina; Jean-Pierre David
The role of Wnt proteins in arthritis.
Nature clinical practice. Rheumatology 2008;4(9):473-80.
2008: Jörg H W Distler; Georg Schett; Steffen Gay; Oliver Distler
The controversial role of tumor necrosis factor alpha in fibrotic diseases.
Arthritis and rheumatism 2008;58(8):2228-35.
2008: Alfiya Akhmetshina; Clara Dees; Margarita Pileckyte; Gabriella Szucs; Bernd M Spriewald; Jochen Zwerina; Oliver Distler; Georg Schett; Jörg H W Distler
Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.
Arthritis and rheumatism 2008;58(8):2553-64.
2008: Jörg H W Distler; Bernhard Manger; Bernd M Spriewald; Georg Schett; Oliver Distler
Treatment of pulmonary fibrosis for twenty weeks with imatinib mesylate in a patient with mixed connective tissue disease.
Arthritis and rheumatism 2008;58(8):2538-42.
2008: Alfiya Akhmetshina; Clara Dees; Margarita Pileckyte; Britta Maurer; Roland Axmann; Astrid Jüngel; Jochen Zwerina; Steffen Gay; Georg Schett; Oliver Distler; Jörg H W Distler
Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(7):2214-22.
2008: Georg Schett; Jochen Zwerina; Gary S Firestein
The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis.
Annals of the rheumatic diseases 2008;67(7):909-16.
2008: Jürgen Rech; Axel J Hueber; Stefan Kallert; Jan Leipe; Jochen R Kalden; Marcus Beck; Georg Schett; Hendrik Schulze-Koops
Remission of demyelinating polyneuropathy with immunoadsorption, low dose corticosteroids and anti-CD20 monoclonal antibody.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2008;12(3):205-8.
2008: Sonja Herman; Gerhard Krönke; Georg Schett
Molecular mechanisms of inflammatory bone damage: emerging targets for therapy.
Trends in molecular medicine 2008;14(6):245-53.
2008: Wolfgang Sipos; Martina Rauner; Monika Skalicky; Andrus Viidik; Günther Hofbauer; Georg Schett; Kurt Redlich; Susanna Lang; Peter Pietschmann
Running has a negative effect on bone metabolism and proinflammatory status in male aged rats.
Experimental gerontology 2008;43(6):578-83.
2008: Karin Polzer; T Karonitsch; T Neumann; G Eger; C Haberler; A Soleiman; B Hellmich; E Csernok; J Distler; Bernhard Manger; Kurt Redlich; Georg Schett; Jochen Zwerina
Eotaxin-3 is involved in Churg-Strauss syndrome--a serum marker closely correlating with disease activity.
Rheumatology (Oxford, England) 2008;47(6):804-8.
2008: Catherine Skhirtladze; Oliver Distler; Clara Dees; Alfiya Akhmetshina; Nicole Busch; Paulius Venalis; Jochen Zwerina; Bernd M Spriewald; Margarita Pileckyte; Georg Schett; Jörg H W Distler
Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis.
Arthritis and rheumatism 2008;58(5):1475-84.
2008: Esther Jimenez-Boj; Nancy Kedersha; Makiyeh Tohidast-Akrad; Franz M Karlhofer; Georg Stummvoll; Christof Zimmermann; Walter Ulrich; Serena Guiducci; Elisabeth Hoefler; Martin Aringer; Georg Schett; Marco Matucci-Cerinic; Josef S Smolen; Günter Steiner
Autoantibodies to the translational suppressors T cell intracytoplasmic antigen 1 and T cell intracytoplasmic antigen 1-related protein in patients with rheumatic diseases: increased prevalence in systemic lupus erythematosus and systemic sclerosis and correlation with clinical features.
Arthritis and rheumatism 2008;58(5):1226-36.
2008: Karin Polzer; A Soleiman; W Baum; R Axmann; J Distler; K Redlich; A Kilian; G Krönke; Georg Schett; Jochen Zwerina
Selective p38MAPK isoform expression and activation in antineutrophil cytoplasmatic antibody-associated crescentic glomerulonephritis: role of p38MAPKalpha.
Annals of the rheumatic diseases 2008;67(5):602-8.
2008: Georg Schett
Review: Immune cells and mediators of inflammatory arthritis.
Autoimmunity 2008;41(3):224-9.
2008: Georg Schett
[Early rheumatoid arthritis].
Der Internist 2008;49(3):263-70.
2008: Uta Schurigt; Klaus M Hummel; Peter Petrow; Mieczyslaw Gajda; Renate Stöckigt; Peter Middel; Jochen Zwerina; Tobias Janik; Ricardo Bernhardt; Susann Schüler; Dieter Scharnweber; Felix Beckmann; Paul Saftig; george kollias; Georg Schett; Bernd Wiederanders; Rolf Bräuer
Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.
Arthritis and rheumatism 2008;58(2):422-34.
2008: Klaus Bobacz; Ilse-Gerlinde Sunk; Silvia Hayer; Love Amoyo; Makiyeh Tohidast-Akrad; george kollias; Josef S Smolen; Georg Schett
Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: potential importance for cartilage breakdown and synovial hypertrophy.
Arthritis and rheumatism 2008;58(1):109-18.
2007: Jörg H W Distler; Astrid Jüngel; Margarita Pileckyte; Jochen Zwerina; Beat A Michel; Renate E Gay; Otylia Kowal-Bielecka; Marco Matucci-Cerinic; Georg Schett; Hugo H Marti; Steffen Gay; Oliver Distler
Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis.
Arthritis and rheumatism 2007;56(12):4203-15.
2007: Mario M Zaiss; Roland Axmann; Jochen Zwerina; Karin Polzer; Eva Gückel; Alla Skapenko; Hendrik Schulze-Koops; Nikki Horwood; Andrew Cope; Georg Schett
Treg cells suppress osteoclast formation: a new link between the immune system and bone.
Arthritis and rheumatism 2007;56(12):4104-12.
2007: Markus H Hoffmann; Jonatan Tuncel; Karl Skriner; Makiyeh Tohidast-Akrad; Birgit Türk; Serafin Pinol-Roma; Guy Serre; Georg Schett; Josef S Smolen; Rikard Holmdahl; Günter Steiner
The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7568-76.
2007: Georg Schett
Joint remodelling in inflammatory disease.
Annals of the rheumatic diseases 2007;66 Suppl 3():iii42-4.
2007: E Aigner; I Schmid; Christoph H Osterreicher; Jochen Zwerina; Georg Schett; M Strasser; F Niksic; Florian Hohla; Thomas Ramsauer; Ulrich Dorn; Wolfgang Patsch; Christian Datz
Contribution of anti-cyclic citrullinated peptide antibody and rheumatoid factor to the diagnosis of arthropathy in haemochromatosis.
Annals of the rheumatic diseases 2007;66(9):1249-51.
2007: Stefan Kiechl; Georg Schett; Judith Schwaiger; Klaus Seppi; Paula Eder; Georg Egger; Peter Santer; Andreas J Mayr; Qingbo Xu; Johann Willeit
Soluble receptor activator of nuclear factor-kappa B ligand and risk for cardiovascular disease.
Circulation 2007;116(4):385-91.
2007: Jochen Zwerina; Kurt Redlich; Karin Polzer; Leo Joosten; Gerhard Krönke; Jörg H W Distler; Andreas Hess; Noreen Pundt; Thomas Pap; Oskar Hoffmann; Juerg Gasser; Clemens Scheinecker; Josef S Smolen; Wim van den Berg; Georg Schett
TNF-induced structural joint damage is mediated by IL-1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(28):11742-7.
2007: Axel J Hueber; Andac Tunc; Georg Schett; Bernhard Manger
Anti-tumour necrosis factor alpha therapy in patients with impaired renal function.
Annals of the rheumatic diseases 2007;66(7):981-2.
2007: Iain B McInnes; Georg Schett
Cytokines in the pathogenesis of rheumatoid arthritis.
Nature reviews. Immunology 2007;7(6):429-42.
2007: Karin Polzer; Georg Schett; Jochen Zwerina
The lonely death: chondrocyte apoptosis in TNF-induced arthritis.
Autoimmunity 2007;40(4):333-6.
2007: Georg Schett; Robert Landewé; Désirée van der Heijde
Tumour necrosis factor blockers and structural remodelling in ankylosing spondylitis: what is reality and what is fiction?
Annals of the rheumatic diseases 2007;66(6):709-11.
2007: Jochen Zwerina; Enijad Sahimbegovic; Bernhard Manger; Georg Schett
Clinical images: rheumatologic irony.
Arthritis and rheumatism 2007;56(5):1463.
2007: Georg Schett
How does joint remodeling work?: new insights in the molecular regulation of the architecture of joints.
Cell adhesion & migration 2007;1(2):102-3.
2007: Esther Jimenez-Boj; Iris Nöbauer-Huhmann; Beatrice Hanslik-Schnabel; Ronald Dorotka; Axel Wanivenhaus; Franz Kainberger; Siegfried Trattnig; Roland Axmann; Wayne Tsuji; Sonja Hermann; Josef Smolen; Georg Schett
Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis.
Arthritis and rheumatism 2007;56(4):1118-24.
2007: Stefan Wöhrer; Marlene Troch; Jochen Zwerina; Georg Schett; Cathrin Skrabs; Alexander Gaiger; Ulrich Jaeger; Christoph C Zielinski; Markus Raderer
Influence of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone on serologic parameters and clinical course in lymphoma patients with autoimmune diseases.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(4):647-51.
2007: Danielle Diarra; Marina Stolina; Karin Polzer; Jochen Zwerina; Michael Ominsky; Denise Dwyer; Adelheid Korb; Josef Smolen; Markus Hoffmann; Clemens Scheinecker; Desiree van der Heide; Robert Landewe; Dave Lacey; William G Richards; Georg Schett
Dickkopf-1 is a master regulator of joint remodeling.
Nature medicine 2007;13(2):156-63.
2007: Georg Schett; Birgit Tuerk
Bone histomorphometry in arthritis models.
Methods in molecular medicine 2007;135():269-83.
2007: Georg Schett
Erosive arthritis.
Arthritis research & therapy 2007;9 Suppl 1():S2.
2007: Georg Schett
Cells of the synovium in rheumatoid arthritis. Osteoclasts.
Arthritis research & therapy 2007;9(1):203.
2007: Jörg H W Distler; Astrid Jüngel; Lars C Huber; Ursula Schulze-Horsel; Jochen Zwerina; Renate E Gay; Beat A Michel; Thomas Hauser; Georg Schett; Steffen Gay; Oliver Distler
Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.
Arthritis and rheumatism 2007;56(1):311-22.
2007: Silvia Hayer; Kurt Redlich; Adelheid Korb; Sonja Hermann; Josef Smolen; Georg Schett
Tenosynovitis and osteoclast formation as the initial preclinical changes in a murine model of inflammatory arthritis.
Arthritis and rheumatism 2007;56(1):79-88.
2006: Georg Schett; Stefan Kiechl; Siegfried Weger; Angelo Pederiva; Andreas J Mayr; Manuele Petrangeli; Friedrich Oberhollenzer; Rolando Lorenzini; Kurt Redlich; Roland Axmann; Jochen Zwerina; Johann Willeit
High-sensitivity C-reactive protein and risk of nontraumatic fractures in the Bruneck study.
Archives of internal medicine 2006;166(22):2495-501.
2006: Stefan Kiechl; Philipp Werner; Michael Knoflach; Martin Furtner; Johann Willeit; Georg Schett
The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease.
Expert review of cardiovascular therapy 2006;4(6):801-11.
2006: Adelheid Korb; Makiyeh Tohidast-Akrad; Erdal Cetin; Roland Axmann; Josef Smolen; Georg Schett
Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis.
Arthritis and rheumatism 2006;54(9):2745-56.
2006: Jochen Zwerina; E Feierl; I Noebauer; A Soleiman; J S Smolen; Kurt Redlich; Georg Schett
Against the current--when primary pericardial disease causes rheumatic disease.
Rheumatology (Oxford, England) 2006;45(8):1042-3.
2006: Georg Schett
Arthritis -- a nightmare for bone.
Wiener klinische Wochenschrift 2006;118(1-2):11-5.
2006: Jochen Zwerina; Silvia Hayer; Kurt Redlich; Klaus Bobacz; george kollias; Josef S Smolen; Georg Schett
Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction.
Arthritis and rheumatism 2006;54(2):463-72.
2006: Kimberly J Hamilton; Georg Schett; Charles F Reich; Josef S Smolen; David S Pisetsky
The binding of sera of patients with SLE to bacterial and mammalian DNA.
Clinical immunology (Orlando, Fla.) 2006;118(2-3):209-18.
2006: Jochen Zwerina; Birgit Tuerk; Kurt Redlich; Josef S Smolen; Georg Schett
Imbalance of local bone metabolism in inflammatory arthritis and its reversal upon tumor necrosis factor blockade: direct analysis of bone turnover in murine arthritis.
Arthritis research & therapy 2006;8(1):R22.
2006: Georg Schett
Rheumatoid arthritis: inflammation and bone loss.
Wiener medizinische Wochenschrift (1946) 2006;156(1-2):34-41.
2005: Silvia Hayer; Makiyeh Tohidast-Akrad; Sylva Haralambous; Beatrice Jahn-Schmid; Karl Skriner; Sylvie Trembleau; Hélène Dumortier; Serafin Pinol-Roma; Kurt Redlich; Georg Schett; Sylviane Muller; george kollias; Josef Smolen; Günter Steiner
Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):8327-36.
2005: Qingzhong Xiao; Kaushik Mandal; Georg Schett; Manuel Mayr; Georg Wick; Friedrich Oberhollenzer; Johann Willeit; Stefan Kiechl; Qingbo Xu
Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study.
Stroke; a journal of cerebral circulation 2005;36(12):2571-6.
2005: Jochen Zwerina; sotiria tzima; Silvia Hayer; Kurt Redlich; Oskar Hoffmann; Beatrice Hanslik-Schnabel; Josef S Smolen; george kollias; Georg Schett
Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2011-3.
2005: Georg Schett; Silvia Hayer; Jochen Zwerina; Kurt Redlich; Josef S Smolen
Mechanisms of Disease: the link between RANKL and arthritic bone disease.
Nature clinical practice. Rheumatology 2005;1(1):47-54.
2005: Georg Schett; Marina Stolina; Brad Bolon; Scot Middleton; Matthew Adlam; Heather Brown; Li Zhu; Ulrich Feige; Debra Zack
Analysis of the kinetics of osteoclastogenesis in arthritic rats.
Arthritis and rheumatism 2005;52(10):3192-201.
2005: Marina Stolina; Stephen Adamu; Michael Ominsky; Denise Dwyer; Frank Asuncion; Zhaopo Geng; Scot Middleton; Heather Brown; Jim Pretorius; Georg Schett; Brad Bolon; Ulrich Feige; Debra Zack; Paul J Kostenuik
RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(10):1756-65.
2005: Esther Jimenez-Boj; Kurt Redlich; Birgit Türk; Beatrice Hanslik-Schnabel; Axel Wanivenhaus; Andreas Chott; Josef S Smolen; Georg Schett
Interaction between synovial inflammatory tissue and bone marrow in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2579-88.
2005: Josef S Smolen; Kurt Redlich; Jochen Zwerina; Daniel Aletaha; Günter Steiner; Georg Schett
Pro-inflammatory cytokines in rheumatoid arthritis: pathogenetic and therapeutic aspects.
Clinical reviews in allergy & immunology 2005;28(3):239-48.
2005: Jochen Zwerina; Kurt Redlich; Georg Schett; Josef S Smolen
Pathogenesis of rheumatoid arthritis: targeting cytokines.
Annals of the New York Academy of Sciences 2005;1051():716-29.
2005: Maria Grazia Ruocco; Shin Maeda; Jin Mo Park; Toby Lawrence; Li-Chung Hsu; Yixue Cao; Georg Schett; Erwin F Wagner; Michael Karin
I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss.
The Journal of experimental medicine 2005;201(10):1677-87.
2005: Georg Schett; Scot Middleton; Brad Bolon; Marina Stolina; Heather Brown; Li Zhu; Jim Pretorius; Debra Zack; Paul J Kostenuik; Ulrich Feige
Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models.
Arthritis and rheumatism 2005;52(5):1604-11.
2005: Georg Schett; Petra Herak; Wolfgang Graninger; Josef S Smolen; Martin Aringer
Listeria-associated arthritis in a patient undergoing etanercept therapy: case report and review of the literature.
Journal of clinical microbiology 2005;43(5):2537-41.
2005: Teiji Wada; Tomoki Nakashima; Antonio J Oliveira-dos-Santos; Juerg Gasser; Hiromitsu Hara; Georg Schett; Josef M Penninger
The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis.
Nature medicine 2005;11(4):394-9.
2005: Silvia Hayer; Günter Steiner; Birgit Görtz; Erika Reiter; Makiyeh Tohidast-Akrad; Michael Amling; Oskar Hoffmann; Kurt Redlich; Jochen Zwerina; Karl Skriner; Frank Hilberg; Erwin F Wagner; Josef S Smolen; Georg Schett
CD44 is a determinant of inflammatory bone loss.
The Journal of experimental medicine 2005;201(6):903-14.
2005: Birgit Görtz; Silvia Hayer; Birgit Tuerck; Jochen Zwerina; Josef S Smolen; Georg Schett
Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo.
Arthritis research & therapy 2005;7(5):R1140-7.
2005: Georg Schett; Josef S Smolen
New insights in the mechanism of bone loss in arthritis.
Current pharmaceutical design 2005;11(23):3039-49.
2005: Marcus Köller; Silvia Hayer; Kurt Redlich; Romeo Ricci; Jean-Pierre David; Günter Steiner; Josef S Smolen; Erwin F Wagner; Georg Schett
JNK1 is not essential for TNF-mediated joint disease.
Arthritis research & therapy 2005;7(1):R166-73.
2004: Georg Schett; Stefan Kiechl; Enzo Bonora; Kurt Redlich; Wolfgang Woloszczuk; Friedrich Oberhollenzer; Josef Jocher; Romolo Dorizzi; Michele Muggeo; Josef Smolen; Johann Willeit
Serum leptin level and the risk of nontraumatic fracture.
The American journal of medicine 2004;117(12):952-6.
2004: Petra Herrak; Birgit Görtz; Silvia Hayer; Kurt Redlich; Erika Reiter; Jürg Gasser; Helga Bergmeister; george kollias; Josef S Smolen; Georg Schett
Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis.
Arthritis and rheumatism 2004;50(7):2327-37.
2004: J S Smolen; Silvia Hayer; Georg Schett; Kurt Redlich; Martin Aringer; george kollias; E Wagner; Günter Steiner
Autoimmunity and rheumatoid arthritis.
Autoimmunity reviews 2004;3 Suppl 1():S23.
2004: Peter Faybik; D Wachauer; Hubert Hetz; T Bachleitner; Heinz Steltzer; Georg Schett; Claus G Krenn
Perioperative kinetics of heat shock protein 60 in serum during orthotopic liver transplantation.
Transplantation proceedings 2004;36(5):1469-72.
2004: Birgit Görtz; Silvia Hayer; Kurt Redlich; Jochen Zwerina; Makiyeh Tohidast-Akrad; Birgit Tuerk; Christine Hartmann; george kollias; Günter Steiner; Josef S Smolen; Georg Schett
Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(6):990-8.
2004: Stefan Kiechl; Georg Schett; Gregor Wenning; Kurt Redlich; Martin Oberhollenzer; Andreas J Mayr; Peter Santer; Josef Smolen; Werner Poewe; Johann Willeit
Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease.
Circulation 2004;109(18):2175-80.
2004: Georg Schett; Stefan Kiechl; Kurt Redlich; Friedrich Oberhollenzer; Siegfried Weger; Georg Egger; Andreas J Mayr; Josef Jocher; Qingbo Xu; Peter Pietschmann; Steven Teitelbaum; Josef Smolen; Johann Willeit
Soluble RANKL and risk of nontraumatic fracture.
JAMA : the journal of the American Medical Association 2004;291(9):1108-13.
2004: Kurt Redlich; Birgit Görtz; Silvia Hayer; Jochen Zwerina; george kollias; Günter Steiner; Josef S Smolen; Georg Schett
Overexpression of tumor necrosis factor causes bilateral sacroiliitis.
Arthritis and rheumatism 2004;50(3):1001-5.
2004: Kurt Redlich; Birgit Görtz; Silvia Hayer; Jochen Zwerina; Nicholas Doerr; Paul J Kostenuik; Helga Bergmeister; george kollias; Günter Steiner; Josef S Smolen; Georg Schett
Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.
The American journal of pathology 2004;164(2):543-55.
2004: Jochen Zwerina; Silvia Hayer; Makiyeh Tohidast-Akrad; Helga Bergmeister; Kurt Redlich; Ulrich Feige; Colin Dunstan; george kollias; Günter Steiner; Josef Smolen; Georg Schett
Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction.
Arthritis and rheumatism 2004;50(1):277-90.
2003: Kurt Redlich; Georg Schett; Günter Steiner; Silvia Hayer; Erwin F Wagner; Josef S Smolen
Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade.
Arthritis and rheumatism 2003;48(12):3308-19.
2003: Georg Schett; Carl Walter STEINER; Qingbo Xu; Josef S Smolen; Günter Steiner
TNFalpha mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response.
Cell death and differentiation 2003;10(10):1126-36.
2003: Georg Schett; Kurt Redlich; Silvia Hayer; Jochen Zwerina; Brad Bolon; Colin Dunstan; Birgit Görtz; Andreas Schulz; Helga Bergmeister; george kollias; Günter Steiner; Josef S Smolen
Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice.
Arthritis and rheumatism 2003;48(7):2042-51.
2003: Georg Schett; Kurt Redlich; Josef S Smolen
The role of osteoprotegerin in arthritis.
Arthritis research & therapy 2003;5(5):239-45.
2002: Kurt Redlich; Silvia Hayer; Romeo Ricci; Jean-Pierre David; Makiyeh Tohidast-Akrad; george kollias; Günter Steiner; Josef S Smolen; Erwin F Wagner; Georg Schett
Osteoclasts are essential for TNF-alpha-mediated joint destruction.
The Journal of clinical investigation 2002;110(10):1419-27.
2002: Georg Schett; S Winkler; Ursula Hollenstein; Gabriele Amann; M Willheim; M Prokop; W Klepetko; Alexander Becherer; Josef Smolen; Wolfgang Graninger
Obstruction of the pulmonary artery by granulomatous vasculitis: a clinical, morphological, and immunological analysis.
Annals of the rheumatic diseases 2002;61(5):463-7.
2002: Kurt Redlich; Silvia Hayer; Andrea Maier; Colin Dunstan; Makiyeh Tohidast-Akrad; Susanne Lang; Birgit Türk; Peter Pietschmann; Wolfgang Woloszczuk; Sylva Haralambous; george kollias; Günter Steiner; Josef S Smolen; Georg Schett
Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin.
Arthritis and rheumatism 2002;46(3):785-92.
2002: Georg Schett; J Smole; C Zimmermann; H Hiesberger; E Hoefler; S Fournel; S Muller; R L Rubin; Günter Steiner
The autoimmune response to chromatin antigens in systemic lupus erythematosus: autoantibodies against histone H1 are a highly specific marker for SLE associated with increased disease activity.
Lupus 2002;11(11):704-15.
2002: Wolfgang Füreder; U Firbas; Janet L Nichol; J Pistillo; S Winkler; H Hiesberger; Wolfgang R Sperr; Josef Smolen; Georg Schett
Serum thrombopoietin levels and anti-thrombopoietin antibodies in systemic lupus erythematosus.
Lupus 2002;11(4):221-6.
2001: Georg Schett; Silvia Hayer; Makiyeh Tohidast-Akrad; B J Schmid; Susanne Lang; Birgit Türk; Franz Kainberger; Sylva Haralambous; george kollias; A C Newby; Qingbo Xu; Günter Steiner; Josef Smolen
Adenovirus-based overexpression of tissue inhibitor of metalloproteinases 1 reduces tissue damage in the joints of tumor necrosis factor alpha transgenic mice.
Arthritis and rheumatism 2001;44(12):2888-98.
2001: Georg Schett; U Firbas; Wolfgang Füreder; H Hiesberger; S Winkler; D Wachauer; Marcus Köller; Stylianos Kapiotis; Josef Smolen
Decreased serum erythropoietin and its relation to anti-erythropoietin antibodies in anaemia of systemic lupus erythematosus.
Rheumatology (Oxford, England) 2001;40(4):424-31.
2001: Kurt Redlich; Hans P Kiener; Georg Schett; Makiyeh Tohidast-Akrad; Edgar Selzer; I Radda; Georg H Stummvoll; Carl Walter STEINER; Marion Gröger; Peter Bitzan; P Zenz; Josef S Smolen; Günter Steiner
Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha.
Arthritis and rheumatism 2001;44(2):266-74.
2001: Georg Schett; Makiyeh Tohidast-Akrad; Günter Steiner; Josef Smolen
The stressed synovium.
Arthritis research 2001;3(2):80-6.
2000: Georg Schett; Makiyeh Tohidast-Akrad; Josef S Smolen; B J Schmid; Carl Walter STEINER; Peter Bitzan; P Zenz; Kurt Redlich; Qingbo Xu; Günter Steiner
Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(11):2501-12.
2000: Qingbo Xu; Georg Schett; Hannes Perschinka; Manuel Mayr; Georg Egger; Friedrich Oberhollenzer; Johann Willeit; Stefan Kiechl; Georg Wick
Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population.
Circulation 2000;102(1):14-20.
2000: Georg Schett; R L Rubin; Günter Steiner; H Hiesberger; S Muller; Josef Smolen
The lupus erythematosus cell phenomenon: comparative analysis of antichromatin antibody specificity in lupus erythematosus cell-positive and -negative sera.
Arthritis and rheumatism 2000;43(2):420-8.
2000: Georg Schett; Carl Walter STEINER; S Winkler; Wolfgang Graninger; Josef Smolen; Q Xu; Günter Steiner
[Reciprocal modification of Fas activation and stress protein response decides apoptosis or resistance development of cells].
Acta medica Austriaca 2000;27(3):94-8.
1999: Georg Schett; Bernhard Metzler; R Kleindienst; Albert Amberger; H Recheis; Qingbo Xu; Georg Wick
Myocardial injury leads to a release of heat shock protein (hsp) 60 and a suppression of the anti-hsp65 immune response.
Cardiovascular research 1999;42(3):685-95.
1999: Georg Schett; Carl Walter STEINER; Marion Gröger; S Winkler; Wolfgang Graninger; Josef Smolen; Qingbo Xu; Günter Steiner
Activation of Fas inhibits heat-induced activation of HSF1 and up-regulation of hsp70.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):833-42.
1999: Manuel Mayr; Bernhard Metzler; Stefan Kiechl; Johann Willeit; Georg Schett; Qingbo Xu; Georg Wick
Endothelial cytotoxicity mediated by serum antibodies to heat shock proteins of Escherichia coli and Chlamydia pneumoniae: immune reactions to heat shock proteins as a possible link between infection and atherosclerosis.
Circulation 1999;99(12):1560-6.
1998: Georg Schett; Günter Steiner; Josef S Smolen
Nuclear antigen histone H1 is primarily involved in lupus erythematosus cell formation.
Arthritis and rheumatism 1998;41(8):1446-55.
1998: Georg Schett; Kurt Redlich; Qingbo Xu; P Bizan; Marion Gröger; Makiyeh Tohidast-Akrad; Hans P Kiener; Josef Smolen; Günter Steiner
Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs.
The Journal of clinical investigation 1998;102(2):302-11.
1997: Georg Schett; Bernhard Metzler; R Kleindienst; I Moschèn; R Hattmannsdorfer; H Wolf; T Ottenhoff; Qingbo Xu; Georg Wick
Salivary anti-hsp65 antibodies as a diagnostic marker for gingivitis and a possible link to atherosclerosis.
International archives of allergy and immunology 1997;114(3):246-50.
1997: Albert Amberger; C Maczek; G Jürgens; D Michaelis; Georg Schett; K Trieb; T Eberl; S Jindal; Qingbo Xu; Georg Wick
Co-expression of ICAM-1, VCAM-1, ELAM-1 and Hsp60 in human arterial and venous endothelial cells in response to cytokines and oxidized low-density lipoproteins.
Cell stress & chaperones 1997;2(2):94-103.
1997: Bernhard Metzler; Georg Schett; R Kleindienst; Ruurd van der Zee; T Ottenhoff; Al Hajeer; R Bernstein; Qingbo Xu; Georg Wick
Epitope specificity of anti-heat shock protein 65/60 serum antibodies in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(3):536-41.
1997: Georg Schett; Bernhard Metzler; Manuel Mayr; Albert Amberger; Dietger Niederwieser; R S Gupta; L Mizzen; Qingbo Xu; Georg Wick
Macrophage-lysis mediated by autoantibodies to heat shock protein 65/60.
Atherosclerosis 1997;128(1):27-38.
1996: Qingbo Xu; R Kleindienst; Georg Schett; W Waitz; S Jindal; R S Gupta; Hermann Dietrich; Georg Wick
Regression of arteriosclerotic lesions induced by immunization with heat shock protein 65-containing material in normocholesterolemic, but not hypercholesterolemic, rabbits.
Atherosclerosis 1996;123(1-2):145-55.
1995: Georg Schett; Qingbo Xu; Albert Amberger; R Van der Zee; H Recheis; Johann Willeit; Georg Wick
Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity.
The Journal of clinical investigation 1995;96(6):2569-77.
1995: R Kleindienst; Georg Schett; Albert Amberger; C S Seitz; D Michaelis; Bernhard Metzler; Hermann Dietrich; Qingbo Xu; Georg Wick
Atherosclerosis as an autoimmune condition.
Israel journal of medical sciences 1995;31(10):596-9.
1995: Georg Wick; R Kleindienst; Georg Schett; Albert Amberger; Qingbo Xu
Role of heat shock protein 65/60 in the pathogenesis of atherosclerosis.
International archives of allergy and immunology 1995;107(1-3):130-1.
1995: Georg Wick; Georg Schett; Albert Amberger; R Kleindienst; Qingbo Xu
Is atherosclerosis an immunologically mediated disease?
Immunology today 1995;16(1):27-33.
1994: Qingbo Xu; Georg Schett; C S Seitz; Yanhua Hu; R S Gupta; Georg Wick
Surface staining and cytotoxic activity of heat-shock protein 60 antibody in stressed aortic endothelial cells.
Circulation research 1994;75(6):1078-85.