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Todd Scheuer

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Franck Kalume; John C Oakley; Todd Scheuer; Ruth E Westenbroek; Frank H Yu; Christine S Cheah; William A Catterall
Sudden unexpected death in a mouse model of Dravet syndrome.
Sylvain Brunet; Todd Scheuer; William A Catterall
Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel.
Karina Leal; Sumiko Mochida; Todd Scheuer; William A Catterall
Fine-tuning synaptic plasticity by modulation of Ca(V)2.1 channels with Ca2+ sensor proteins.

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2013: Franck Kalume; John C Oakley; Todd Scheuer; Ruth E Westenbroek; Frank H Yu; Christine S Cheah; William A Catterall
Sudden unexpected death in a mouse model of Dravet syndrome.
The Journal of clinical investigation 2013;123(4):1798-808.
2013: Sylvain Brunet; Todd Scheuer; William A Catterall
Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel.
The Journal of general physiology 2013;141(1):85-94.
2012: Karina Leal; Sumiko Mochida; Todd Scheuer; William A Catterall
Fine-tuning synaptic plasticity by modulation of Ca(V)2.1 channels with Ca2+ sensor proteins.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(42):17069-74.
2012: Sung Han; Gregory B Potter; John L Rubenstein; Todd Scheuer; Chao Tai; Ruth E Westenbroek; Frank H Yu; Christine S Cheah; Horacio O de la Iglesia; William A Catterall
Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.
Nature 2012;489(7416):385-90.
2012: Joel Z Zhang; Lior Cohen; Dalia Gordon; Michael Gurevitz; Izhar Karbat; Todd Scheuer; Vladimir Yarov-Yarovoy; William A Catterall
Mapping the interaction site for a β-scorpion toxin in the pore module of domain III of voltage-gated Na(+) channels.
The Journal of biological chemistry 2012;287(36):30719-28.
2012: Jian Payandeh; Todd Scheuer; Ning Zheng; Tamer Gamal El-Din; William A Catterall
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.
Nature 2012;486(7401):135-9.
2012: Alexandra P Few; Evanthia Nanou; Todd Scheuer; Jane M Sullivan; Hirofumi Watari; William A Catterall
Asynchronous Ca2+ current conducted by voltage-gated Ca2+ (CaV)-2.1 and CaV2.2 channels and its implications for asynchronous neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):E452-60.
2011: Paul G DeCaen; Todd Scheuer; Vladimir Yarov-Yarovoy; William A Catterall
Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(46):18825-30.
2011: Joel Z Zhang; Lior Cohen; Dalia Gordon; Michael Gurevitz; Izhar Karbat; Todd Scheuer; Vladimir Yarov-Yarovoy; William A Catterall
Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels.
The Journal of biological chemistry 2011;286(38):33641-51.
2011: Jinti Wang; Vladimir Yarov-Yarovoy; Dalia Gordon; Michael Gurevitz; Roy Kahn; Todd Scheuer; William A Catterall
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15426-31.
2011: Jian Payandeh; Todd Scheuer; Ning Zheng; William A Catterall
The crystal structure of a voltage-gated sodium channel.
Nature 2011;475(7356):353-8.
2011: Todd Scheuer
Regulation of sodium channel activity by phosphorylation.
Seminars in cell & developmental biology 2011;22(2):160-5.
2010: Stanislav Sokolov; Todd Scheuer; William A Catterall
Ion permeation and block of the gating pore in the voltage sensor of NaV1.4 channels with hypokalemic periodic paralysis mutations.
The Journal of general physiology 2010;136(2):225-36.
2010: Matthew D Fuller; Michelle A Emrick; Martin Sadilek; Todd Scheuer; William A Catterall
Molecular mechanism of calcium channel regulation in the fight-or-flight response.
Science signaling 2010;3(141):ra70.
2010: Susann G Kaufmann; Ruth E Westenbroek; Christoph Zechner; Alexander H Maass; Sebastian Bischoff; Jenny Muck; Erhard Wischmeyer; Todd Scheuer; Sebastian K G Maier
Functional protein expression of multiple sodium channel alpha- and beta-subunit isoforms in neonatal cardiomyocytes.
Journal of molecular and cellular cardiology 2010;48(1):261-9.
2009: Paul G DeCaen; Vladimir Yarov-Yarovoy; Elizabeth M Sharp; Todd Scheuer; William A Catterall
Sequential formation of ion pairs during activation of a sodium channel voltage sensor.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(52):22498-503.
2009: Sylvain Brunet; Todd Scheuer; William A Catterall
Cooperative regulation of Ca(v)1.2 channels by intracellular Mg(2+), the proximal C-terminal EF-hand, and the distal C-terminal domain.
The Journal of general physiology 2009;134(2):81-94.
2009: John C Oakley; Franck Kalume; Frank H Yu; Todd Scheuer; William A Catterall
Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3994-9.
2008: Paul G DeCaen; Vladimir Yarov-Yarovoy; Yong Zhao; Todd Scheuer; William A Catterall
Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15142-7.
2008: Yuan Chen; Frank H Yu; Elizabeth M Sharp; Daniel Beacham; Todd Scheuer; William A Catterall
Functional properties and differential neuromodulation of Na(v)1.6 channels.
Molecular and cellular neurosciences 2008;38(4):607-15.
2008: Stanislav Sokolov; Richard L Kraus; Todd Scheuer; William A Catterall
Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II.
Molecular pharmacology 2008;73(3):1020-8.
2008: Mochida Sumiko; Alexandra P Few; Todd Scheuer; William A Catterall
Regulation of presynaptic Ca(V)2.1 channels by Ca2+ sensor proteins mediates short-term synaptic plasticity.
Neuron 2008;57(2):210-6.
2008: Xin Jiang; Nathan J Lautermilch; Hirofumi Watari; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Modulation of CaV2.1 channels by Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):341-6.
2007: Daniel Beacham; Misol Ahn; William A Catterall; Todd Scheuer
Sites and molecular mechanisms of modulation of Na(v)1.2 channels by Fyn tyrosine kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(43):11543-51.
2007: Misol Ahn; Daniel Beacham; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Regulation of Na(v)1.2 channels by brain-derived neurotrophic factor, TrkB, and associated Fyn kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(43):11533-42.
2007: Franck Kalume; Frank H Yu; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(41):11065-74.
2007: Todd Scheuer
Local anaesthetic block of sodium channels: raising the barrier.
The Journal of physiology 2007;581(Pt 2):423.
2007: W Preston Few; Todd Scheuer; William A Catterall
Dopamine modulation of neuronal Na(+) channels requires binding of A kinase-anchoring protein 15 and PKA by a modified leucine zipper motif.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5187-92.
2007: Stanislav Sokolov; Todd Scheuer; William A Catterall
Gating pore current in an inherited ion channelopathy.
Nature 2007;446(7131):76-8.
2007: William A Catterall; Sandrine Cestèle; Vladimir Yarov-Yarovoy; Frank H Yu; Keiichi Konoki; Todd Scheuer
Voltage-gated ion channels and gating modifier toxins.
Toxicon : official journal of the International Society on Toxinology 2007;49(2):124-41.
2006: Todd Scheuer; William A Catterall
Control of neuronal excitability by phosphorylation and dephosphorylation of sodium channels.
Biochemical Society transactions 2006;34(Pt 6):1299-302.
2006: Joanne T Hulme; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16574-9.
2006: Joanne T Hulme; Vladimir Yarov-Yarovoy; Teddy W-C Lin; Todd Scheuer; William A Catterall
Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C-terminal domain.
The Journal of physiology 2006;576(Pt 1):87-102.
2006: Frank H Yu; Massimo Mantegazza; Ruth E Westenbroek; Carol A Robbins; Franck Kalume; Kimberly A Burton; William J Spain; G Stanley McKnight; Todd Scheuer; William A Catterall
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy.
Nature neuroscience 2006;9(9):1142-9.
2006: Sandrine Cestèle; Vladimir Yarov-Yarovoy; Yusheng Qu; François Sampieri; Todd Scheuer; William A Catterall
Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.
The Journal of biological chemistry 2006;281(30):21332-44.
2006: Yuan Chen; Frank H Yu; Dalton Surmeier; Todd Scheuer; William A Catterall
Neuromodulation of Na+ channel slow inactivation via cAMP-dependent protein kinase and protein kinase C.
Neuron 2006;49(3):409-20.
2005: Sylvain Brunet; Todd Scheuer; Rachel E Klevit; William A Catterall
Modulation of CaV1.2 channels by Mg2+ acting at an EF-hand motif in the COOH-terminal domain.
The Journal of general physiology 2005;126(4):311-23.
2005: Alexandra P Few; Nathan J Lautermilch; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Differential regulation of CaV2.1 channels by calcium-binding protein 1 and visinin-like protein-2 requires N-terminal myristoylation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(30):7071-80.
2005: Nathan J Lautermilch; Alexandra P Few; Todd Scheuer; William A Catterall
Modulation of CaV2.1 channels by the neuronal calcium-binding protein visinin-like protein-2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(30):7062-70.
2005: Stanislav Sokolov; Todd Scheuer; William A Catterall
Ion permeation through a voltage- sensitive gating pore in brain sodium channels having voltage sensor mutations.
Neuron 2005;47(2):183-9.
2005: V Monica Bricelj; Laurie Connell; Keiichi Konoki; Scott P Macquarrie; Todd Scheuer; William A Catterall; Vera L Trainer
Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP.
Nature 2005;434(7034):763-7.
2005: Massimo Mantegazza; Frank H Yu; Andrew J Powell; Jeffrey J Clare; William A Catterall; Todd Scheuer
Molecular determinants for modulation of persistent sodium current by G-protein betagamma subunits.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(13):3341-9.
2005: Barry D Johnson; Todd Scheuer; William A Catterall
Convergent regulation of skeletal muscle Ca2+ channels by dystrophin, the actin cytoskeleton, and cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4191-6.
2005: Yuan Chen; Angela R Cantrell; Robert O Messing; Todd Scheuer; William A Catterall
Specific modulation of Na+ channels in hippocampal neurons by protein kinase C epsilon.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(2):507-13.
2005: Charles T Yokoyama; Scott J Myers; Jian Fu; Susan M Mockus; Todd Scheuer; William A Catterall
Mechanism of SNARE protein binding and regulation of Cav2 channels by phosphorylation of the synaptic protein interaction site.
Molecular and cellular neurosciences 2005;28(1):1-17.
2004: Yong Zhao; Todd Scheuer; William A Catterall
Reversed voltage-dependent gating of a bacterial sodium channel with proline substitutions in the S6 transmembrane segment.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17873-8.
2004: Joanne T Hulme; Todd Scheuer; William A Catterall
Regulation of cardiac ion channels by signaling complexes: role of modified leucine zipper motifs.
Journal of molecular and cellular cardiology 2004;37(3):625-31.
2004: Bin Li; Huijun Zhong; Todd Scheuer; William A Catterall
Functional role of a C-terminal Gbetagamma-binding domain of Ca(v)2.2 channels.
Molecular pharmacology 2004;66(3):761-9.
2004: Chunling Chen; Ruth E Westenbroek; Xiaorong Xu; Chris A Edwards; Dorothy R Sorenson; Yuan Chen; Dyke P McEwen; Heather A O'Malley; Vandana Bharucha; Laurence S Meadows; Gabriel A Knudsen; Alex Vilaythong; Jeffrey L Noebels; Thomas L Saunders; Todd Scheuer; Peter Shrager; William A Catterall; Lori L Isom
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(16):4030-42.
2004: Yong Zhao; Vladimir Yarov-Yarovoy; Todd Scheuer; William A Catterall
A gating hinge in Na+ channels; a molecular switch for electrical signaling.
Neuron 2004;41(6):859-65.
2004: Sebastian K G Maier; Ruth E Westenbroek; Kimberly A McCormick; Rory Curtis; Todd Scheuer; William A Catterall
Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart.
Circulation 2004;109(11):1421-7.
2003: Amy Lee; Hong Zhou; Todd Scheuer; William A Catterall
Molecular determinants of Ca(2+)/calmodulin-dependent regulation of Ca(v)2.1 channels.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):16059-64.
2003: Joanne T Hulme; Teddy W-C Lin; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):13093-8.
2003: David B. Carr; Michelle Day; Angela R Cantrell; Joshua Held; Todd Scheuer; William A Catterall; Dalton Surmeier
Transmitter modulation of slow, activity-dependent alterations in sodium channel availability endows neurons with a novel form of cellular plasticity.
Neuron 2003;39(5):793-806.
2003: Frank H Yu; Ruth E Westenbroek; Inmaculada Silos-Santiago; Kimberly A McCormick; Deborah Lawson; Pei Ge; Holly Ferriera; Jeremiah Lilly; Peter S DiStefano; William A Catterall; Todd Scheuer; Rory Curtis
Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(20):7577-85.
2003: Sebastian K G Maier; Ruth E Westenbroek; Tomoko T Yamanushi; Halina Dobrzynski; Mark R Boyett; William A Catterall; Todd Scheuer
An unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3507-12.
2003: Mochida Sumiko; Ruth E Westenbroek; Charles T Yokoyama; Huijun Zhong; Scott J Myers; Todd Scheuer; Kanako Itoh; William A Catterall
Requirement for the synaptic protein interaction site for reconstitution of synaptic transmission by P/Q-type calcium channels.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2819-24.
2003: G Liu; Vladimir Yarov-Yarovoy; M Nobbs; Jeffrey J Clare; Todd Scheuer; William A Catterall
Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels.
Neuropharmacology 2003;44(3):413-22.
2002: Chunling Chen; Vandana Bharucha; Yuan Chen; Ruth E Westenbroek; Angus Brown; Jyoti D Malhotra; Dorothy Jones; Christy Avery; Patrick J Gillespie; Kristin A Kazen-Gillespie; Katie Kazarinova-Noyes; Peter Shrager; Thomas L Saunders; Robert L Macdonald; Bruce R Ransom; Todd Scheuer; William A Catterall; Lori L Isom
Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):17072-7.
2002: Vladimir Yarov-Yarovoy; Jancy C McPhee; Diane Idsvoog; Caroline Pate; Todd Scheuer; William A Catterall
Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.
The Journal of biological chemistry 2002;277(38):35393-401.
2002: Angela R Cantrell; Victoria C Tibbs; Frank H Yu; Brian J Murphy; Elizabeth M Sharp; Yusheng Qu; William A Catterall; Todd Scheuer
Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15.
Molecular and cellular neurosciences 2002;21(1):63-80.
2002: Sebastian K G Maier; Ruth E Westenbroek; Kenneth A Schenkman; Eric O Feigl; Todd Scheuer; William A Catterall
An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):4073-8.
2002: Amy Lee; Ruth E Westenbroek; Francoise Haeseleer; Krzysztof Palczewski; Todd Scheuer; William A Catterall
Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1.
Nature neuroscience 2002;5(3):210-7.
2002: Joanne T Hulme; Misol Ahn; Stephen D Hauschka; Todd Scheuer; William A Catterall
A novel leucine zipper targets AKAP15 and cyclic AMP-dependent protein kinase to the C terminus of the skeletal muscle Ca2+ channel and modulates its function.
The Journal of biological chemistry 2002;277(6):4079-87.
2001: Massimo Mantegazza; Frank H Yu; William A Catterall; Todd Scheuer
Role of the C-terminal domain in inactivation of brain and cardiac sodium channels.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15348-53.
2001: Yusheng Qu; Rory Curtis; Deborah Lawson; Kevin Gilbride; Pei Ge; Peter S DiStefano; Inmaculada Silos-Santiago; William A Catterall; Todd Scheuer
Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits.
Molecular and cellular neurosciences 2001;18(5):570-80.
2001: Sandrine Cestèle; Todd Scheuer; Massimo Mantegazza; Hervé Rochat; William A Catterall
Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxin.
The Journal of general physiology 2001;118(3):291-302.
2001: Huijun Zhong; Bin Li; Todd Scheuer; William A Catterall
Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2+ channel.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4705-9.
2001: S Herlitze; Huijun Zhong; Todd Scheuer; William A Catterall
Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4699-704.
2001: Vladimir Yarov-Yarovoy; J Brown; Elizabeth M Sharp; Jeffrey J Clare; Todd Scheuer; William A Catterall
Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.
The Journal of biological chemistry 2001;276(1):20-7.
2000: Gregory H Hockerman; Nejmi Dilmac; Todd Scheuer; William A Catterall
Molecular determinants of diltiazem block in domains IIIS6 and IVS6 of L-type Ca(2+) channels.
Molecular pharmacology 2000;58(6):1264-70.
2000: D McHugh; Elizabeth M Sharp; Todd Scheuer; William A Catterall
Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12334-8.
2000: Amy Lee; Todd Scheuer; William A Catterall
Ca2+/calmodulin-dependent facilitation and inactivation of P/Q-type Ca2+ channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6830-8.
2000: C F Ratcliffe; Y Qu; K A McCormick; Victoria C Tibbs; J E Dixon; Todd Scheuer; William A Catterall
A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta.
Nature neuroscience 2000;3(5):437-44.
2000: Adrian J Carter; Matthias Grauert; U Pschorn; Wolf D Bechtel; C Bartmann-Lindholm; Yusheng Qu; Todd Scheuer; William A Catterall; Thomas Weiser
Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4944-9.
1999: Thomas Weiser; Yusheng Qu; William A Catterall; Todd Scheuer
Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits.
Molecular pharmacology 1999;56(6):1238-44.
1999: Yusheng Qu; J C Rogers; S F Chen; KA McCormick; Todd Scheuer; William A Catterall
Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits.
The Journal of biological chemistry 1999;274(46):32647-54.
1999: KA McCormick; J Srinivasan; K White; Todd Scheuer; William A Catterall
The extracellular domain of the beta1 subunit is both necessary and sufficient for beta1-like modulation of sodium channel gating.
The Journal of biological chemistry 1999;274(46):32638-46.
1999: H Zhong; C T Yokoyama; Todd Scheuer; William A Catterall
Reciprocal regulation of P/Q-type Ca2+ channels by SNAP-25, syntaxin and synaptotagmin.
Nature neuroscience 1999;2(11):939-41.
1999: Angela R Cantrell; Victoria C Tibbs; Ruth E Westenbroek; Todd Scheuer; William A Catterall
Dopaminergic modulation of voltage-gated Na+ current in rat hippocampal neurons requires anchoring of cAMP-dependent protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(17):RC21.
1999: Angela R Cantrell; Todd Scheuer; William A Catterall
Voltage-dependent neuromodulation of Na+ channels by D1-like dopamine receptors in rat hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(13):5301-10.
1999: Amy Lee; S T Wong; D Gallagher; Bin Li; D R Storm; Todd Scheuer; William A Catterall
Ca2+/calmodulin binds to and modulates P/Q-type calcium channels.
Nature 1999;399(6732):155-9.
1999: Carol A Rohl; F A Boeckman; C Baker; Todd Scheuer; William A Catterall; Rachel E Klevit
Solution structure of the sodium channel inactivation gate.
Biochemistry 1999;38(3):855-61.
1998: Nancy J Linford; Angela R Cantrell; Yusheng Qu; Todd Scheuer; William A Catterall
Interaction of batrachotoxin with the local anesthetic receptor site in transmembrane segment IVS6 of the voltage-gated sodium channel.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13947-52.
1998: Sandrine Cestèle; Yusheng Qu; J C Rogers; Hervé Rochat; Todd Scheuer; William A Catterall
Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.
Neuron 1998;21(4):919-31.
1998: Peter Gray; B D Johnson; Ruth E Westenbroek; L G Hays; J R Yates; Todd Scheuer; William A Catterall; Brian J Murphy
Primary structure and function of an A kinase anchoring protein associated with calcium channels.
Neuron 1998;20(5):1017-26.
1998: KA McCormick; Lori L Isom; David S Ragsdale; D Smith; Todd Scheuer; William A Catterall
Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunit.
The Journal of biological chemistry 1998;273(7):3954-62.
1998: J C McPhee; David S Ragsdale; Todd Scheuer; William A Catterall
A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation.
The Journal of biological chemistry 1998;273(2):1121-9.
1997: Gregory H Hockerman; BZ Peterson; Elizabeth M Sharp; T N Tanada; Todd Scheuer; William A Catterall
Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non-L-type Ca2+ channel.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14906-11.
1997: Angela R Cantrell; R D Smith; Alan L Goldin; Todd Scheuer; William A Catterall
Dopaminergic modulation of sodium current in hippocampal neurons via cAMP-dependent phosphorylation of specific sites in the sodium channel alpha subunit.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(19):7330-8.
1997: Kimberly A Burton; B D Johnson; Z E Hausken; Ruth E Westenbroek; Rejean L Idzerda; Todd Scheuer; John D Scott; William A Catterall; G Stanley McKnight
Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):11067-72.
1997: J Y Ma; William A Catterall; Todd Scheuer
Persistent sodium currents through brain sodium channels induced by G protein betagamma subunits.
Neuron 1997;19(2):443-52.
1997: BD Johnson; W Zheng; K S Korach; Todd Scheuer; William A Catterall; G M Rubanyi
Increased expression of the cardiac L-type calcium channel in estrogen receptor-deficient mice.
The Journal of general physiology 1997;110(2):135-40.
1997: Gregory H Hockerman; BD Johnson; M R Abbott; Todd Scheuer; William A Catterall
Molecular determinants of high affinity phenylalkylamine block of L-type calcium channels in transmembrane segment IIIS6 and the pore region of the alpha1 subunit.
The Journal of biological chemistry 1997;272(30):18759-65.
1997: BZ Peterson; BD Johnson; Gregory H Hockerman; M Acheson; Todd Scheuer; William A Catterall
Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis.
The Journal of biological chemistry 1997;272(30):18752-8.
1997: S Kellenberger; J W West; William A Catterall; Todd Scheuer
Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channels.
The Journal of general physiology 1997;109(5):607-17.
1997: S Kellenberger; J W West; Todd Scheuer; William A Catterall
Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels.
The Journal of general physiology 1997;109(5):589-605.
1997: V L Trainer; J C McPhee; H Boutelet-Bochan; C Baker; Todd Scheuer; D Babin; J P Demoute; D Guedin; William A Catterall
High affinity binding of pyrethroids to the alpha subunit of brain sodium channels.
Molecular pharmacology 1997;51(4):651-7.
1997: S Herlitze; Gregory H Hockerman; Todd Scheuer; William A Catterall
Molecular determinants of inactivation and G protein modulation in the intracellular loop connecting domains I and II of the calcium channel alpha1A subunit.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1512-6.
1997: BD Johnson; J P Brousal; BZ Peterson; P A Gallombardo; Gregory H Hockerman; Y Lai; Todd Scheuer; William A Catterall
Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(4):1243-55.
1996: S Kellenberger; Todd Scheuer; William A Catterall
Movement of the Na+ channel inactivation gate during inactivation.
The Journal of biological chemistry 1996;271(48):30971-9.
1996: Yusheng Qu; J C Rogers; T N Tanada; William A Catterall; Todd Scheuer
Phosphorylation of S1505 in the cardiac Na+ channel inactivation gate is required for modulation by protein kinase C.
The Journal of general physiology 1996;108(5):375-9.
1996: BD Johnson; Gregory H Hockerman; Todd Scheuer; William A Catterall
Distinct effects of mutations in transmembrane segment IVS6 on block of L-type calcium channels by structurally similar phenylalkylamines.
Molecular pharmacology 1996;50(5):1388-400.
1996: David S Ragsdale; J C McPhee; Todd Scheuer; William A Catterall
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9270-5.
1996: J C Rogers; Yusheng Qu; T N Tanada; Todd Scheuer; William A Catterall
Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit.
The Journal of biological chemistry 1996;271(27):15950-62.
1996: Angela R Cantrell; J Y Ma; Todd Scheuer; William A Catterall
Muscarinic modulation of sodium current by activation of protein kinase C in rat hippocampal neurons.
Neuron 1996;16(5):1019-26.
1996: S Herlitze; D E Garcia; Ken Mackie; Bertil Hille; Todd Scheuer; William A Catterall
Modulation of Ca2+ channels by G-protein beta gamma subunits.
Nature 1996;380(6571):258-62.
1995: Yusheng Qu; J Rogers; T Tanada; Todd Scheuer; William A Catterall
Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11839-43.
1995: Lori L Isom; David S Ragsdale; K S De Jongh; Ruth E Westenbroek; B F Reber; Todd Scheuer; William A Catterall
Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif.
Cell 1995;83(3):433-42.
1995: Yusheng Qu; Lori L Isom; Ruth E Westenbroek; J C Rogers; T N Tanada; K A McCormick; Todd Scheuer; William A Catterall
Modulation of cardiac Na+ channel expression in Xenopus oocytes by beta 1 subunits.
The Journal of biological chemistry 1995;270(43):25696-701.
1995: Gregory H Hockerman; BD Johnson; Todd Scheuer; William A Catterall
Molecular determinants of high affinity phenylalkylamine block of L-type calcium channels.
The Journal of biological chemistry 1995;270(38):22119-22.
1995: J C McPhee; David S Ragsdale; Todd Scheuer; William A Catterall
A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation.
The Journal of biological chemistry 1995;270(20):12025-34.
1995: Lori L Isom; Todd Scheuer; A B Brownstein; David S Ragsdale; Brian J Murphy; William A Catterall
Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line.
The Journal of biological chemistry 1995;270(7):3306-12.
1994: J Y Ma; M Li; William A Catterall; Todd Scheuer
Modulation of brain Na+ channels by a G-protein-coupled pathway.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12351-5.
1994: J C McPhee; David S Ragsdale; Todd Scheuer; William A Catterall
A mutation in segment IVS6 disrupts fast inactivation of sodium channels.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12346-50.
1994: B D Johnson; Todd Scheuer; William A Catterall
Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11492-6.
1994: David S Ragsdale; J C McPhee; Todd Scheuer; William A Catterall
Molecular determinants of state-dependent block of Na+ channels by local anesthetics.
Science (New York, N.Y.) 1994;265(5179):1724-8.
1994: R Numann; S D Hauschka; William A Catterall; Todd Scheuer
Modulation of skeletal muscle sodium channels in a satellite cell line by protein kinase C.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(7):4226-36.
1994: G Eaholtz; Todd Scheuer; William A Catterall
Restoration of inactivation and block of open sodium channels by an inactivation gate peptide.
Neuron 1994;12(5):1041-8.
1994: Yusheng Qu; J Rogers; T Tanada; Todd Scheuer; William A Catterall
Modulation of cardiac Na+ channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3289-93.
1993: A Sculptoreanu; E Rotman; M Takahashi; Todd Scheuer; William A Catterall
Voltage-dependent potentiation of the activity of cardiac L-type calcium channel alpha 1 subunits due to phosphorylation by cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10135-9.
1993: M Li; J W West; R Numann; B J Murphy; Todd Scheuer; William A Catterall
Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase.
Science (New York, N.Y.) 1993;261(5127):1439-42.
1993: A Sculptoreanu; Todd Scheuer; William A Catterall
Voltage-dependent potentiation of L-type Ca2+ channels due to phosphorylation by cAMP-dependent protein kinase.
Nature 1993;364(6434):240-3.
1993: David S Ragsdale; R Numann; William A Catterall; Todd Scheuer
Inhibition of Na+ channels by the novel blocker PD85,639.
Molecular pharmacology 1993;43(6):949-54.
1992: J W West; D E Patton; Todd Scheuer; Y Wang; Alan L Goldin; William A Catterall
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10910-4.
1992: M Li; J W West; Y Lai; Todd Scheuer; William A Catterall
Functional modulation of brain sodium channels by cAMP-dependent phosphorylation.
Neuron 1992;8(6):1151-9.
1992: J W West; R Numann; B J Murphy; Todd Scheuer; William A Catterall
Phosphorylation of a conserved protein kinase C site is required for modulation of Na+ currents in transfected Chinese hamster ovary cells.
Biophysical journal 1992;62(1):31-3.
1992: A Sculptoreanu; M Morton; C L Gartside; Stephen D Hauschka; William A Catterall; Todd Scheuer
Tetrodotoxin-insensitive sodium channels in a cardiac cell line from a transgenic mouse.
The American journal of physiology 1992;262(3 Pt 1):C724-30.
1992: J W West; Todd Scheuer; L Maechler; William A Catterall
Efficient expression of rat brain type IIA Na+ channel alpha subunits in a somatic cell line.
Neuron 1992;8(1):59-70.
1991: J W West; R Numann; B J Murphy; Todd Scheuer; William A Catterall
A phosphorylation site in the Na+ channel required for modulation by protein kinase C.
Science (New York, N.Y.) 1991;254(5033):866-8.
1991: David S Ragsdale; Todd Scheuer; William A Catterall
Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs.
Molecular pharmacology 1991;40(5):756-65.
1991: R Numann; William A Catterall; Todd Scheuer
Functional modulation of brain sodium channels by protein kinase C phosphorylation.
Science (New York, N.Y.) 1991;254(5028):115-8.
1991: William A Catterall; Todd Scheuer; W Thomsen; S Rossie
Structure and modulation of voltage-gated ion channels.
Annals of the New York Academy of Sciences 1991;625():174-80.
1990: Todd Scheuer; V J Auld; S Boyd; J Offord; R Dunn; William A Catterall
Functional properties of rat brain sodium channels expressed in a somatic cell line.
Science (New York, N.Y.) 1990;247(4944):854-8.
1989: P Vassilev; Todd Scheuer; William A Catterall
Inhibition of inactivation of single sodium channels by a site-directed antibody.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8147-51.
1988: P M Vassilev; Todd Scheuer; William A Catterall
Identification of an intracellular peptide segment involved in sodium channel inactivation.
Science (New York, N.Y.) 1988;241(4873):1658-61.